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Isoforms Recommended:	CDK2

Results for "

CDK2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AAK1 (1) Akt (3) Anaplastic lymphoma kinase (ALK) (2) Angiotensin-converting Enzyme (ACE) (1) Apoptosis (57) ATM/ATR (1) Aurora Kinase (2) Autophagy (7) Bacterial (1) Bcl-2 Family (1) c-Kit (1) Calcium Channel (1) Carbonic Anhydrase (4) Casein Kinase (1) Caspase (2) CDK (187) CFTR (1) Checkpoint Kinase (Chk) (8) Cholinesterase (ChE) (1) COX (1) CXCR (2) Cyclin G-associated Kinase (GAK) (1) DNA/RNA Synthesis (3) E1/E2/E3 Enzyme (1) E3 Ligase Ligand-Linker Conjugates (1) EGFR (10) Endogenous Metabolite (1) Enterovirus (1) ERK (2) FAK (1) FGFR (1) FLT3 (6) GLUT (1) GSK-3 (17) HDAC (2) HIV (2) IKK (1) JAK (6) JNK (3) Ligands for Target Protein for PROTAC (1) LIM Kinase (LIMK) (1) MAPKAPK2 (MK2) (2) MDM-2/p53 (1) MEK (2) Microtubule/Tubulin (2) Molecular Glues (3) mTOR (2) Necroptosis (1) NEKs (1) P-glycoprotein (1) Parasite (1) PARP (1) Phosphatase (1) PI3K (5) Pim (1) PKA (1) PKC (6) PKD (1) PROTAC Linkers (2) PROTACs (9) Reactive Oxygen Species (1) Reverse Transcriptase (1) ROS Kinase (1) Salt-inducible Kinase (SIK) (1) Small Interfering RNA (siRNA) (5) SphK (2) Src (2) Topoisomerase (2) Trk Receptor (1) VEGFR (5) Wee1 (2)
By Research Areas:	Cancer (203) Cardiovascular Disease (2) Infection (3) Inflammation/Immunology (10) Metabolic Disease (3) Neurological Disease (13)
Click Chemistry:	Alkynes (2)
Oligonucleotides:	Pre-designed siRNA Sets (5) siRNAs (5)

225

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

CDK2 degrader 2	PROTACs CDK	Others
CDK2 degrader 2 is a PROTAC class *CDK2* degrader. The CDK2 binding moiety (CBM) binds to the *CDK2* protein and subsequently undergoes ubiquitination, leading to the degradation of *CDK2* through the ubiquitin proteasome pathway (UPP). CDK2 degrader 2 can cause degradation of *CDK2* in MKN1 cells, with a DC₅₀ value less than 100 nM and an average D_max value greater than 75%. (Red: CBM; Blue: DIM; Black: linker)

CVT-313 5+ Cited Publications CDK2 Inhibitor III	CDK	Cancer
CVT-313 (Cdk2 Inhibitor III) is a potent, selective, reversible, and ATP-competitive inhibitor of *CDK2* with IC₅₀ of 0.5 μM. CVT-313 inhibits CDC5L phosphorylation .

CDK2 degrader 1	PROTACs CDK	Cancer
CDK2 degrader 1 (Compound 3) is an orally active cyclin-dependent kinase 2 (CDK2) degrader based on PROTAC technology. CDK2 degrader 1 binds to cereblon to induce ubiquitination and subsequent proteasomal degradation of the *CDK2. CDK2* degrader 1 is used in the research of a wide range of cancers (Red: spiro[3.3]heptan-2- ylmethyl carbonochloridate; Blue: N,N-diisopropylethylamine; Black: linker) .

CDK2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) CDK	Others
CDK2 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cdk2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA) CDK	Others
Cdk2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdk2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cdk2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA) CDK	Others
Cdk2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdk2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

CDK2-IN-15	CDK	Cardiovascular Disease Cancer
CDK2-IN-15 (Compound 19) is an inhibitor of *CDK2* with an IC₅₀ of 2.9 μM. CDK2-IN-15 can be used for cancer research .

CDK2-IN-20	CDK	Cancer
CDK2-IN-20 (compound 3b) is an inhibitor of *CDK2. CDK2-IN-20 has cytotoxicity* on tumor cells presenting an IC₅₀ range of 5.52-17.09 µM. CDK2-IN-20 arrests the MCF-7 cell cycle at the S phase and induces apoptosis .

CDK2/4-IN-2	CDK	Cancer
CDK2/4-IN-2 (compound 56) is a *CDK2* and *CDK4* dual inhibitor with IC₅₀s less than 100 nM. CDK2/4-IN-2 can be used in the study of cancer .

CDK2/MDM2-IN-1	CDK MDM-2/p53	Cancer
CDK2/MDM2-IN-1 (III-13) is a dual inhibitor of CDK2/MDM2 with an IC₅₀ value of 2.60 nM for CDK2. CDK2/MDM2-IN-1 has antitumor activity .

CDK2/4/6-IN-1	CDK	Cancer
CDK2/4/6-IN-1(example 29) is a *CDK2/4/6* inhibitor with IC₅₀ values of 2.5, 23.7 and 44.3 nM for CDK2, CDK4 and CDK6, respectively. CDK2/4/6-IN-1 can be used in cancer research . CDK2/4/6-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CDK2-IN-11	CDK Carbonic Anhydrase	Cancer
CDK2-IN-11 (compound 9d) is a potent *CDK2* inhibitor with an IC₅₀ of 6.4 μM, and K_I values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer .

CDK2-IN-24	CDK	Cancer
CDK2-IN-24 (compound 3f) is an inhibitor of cyclin-dependent kinase 2 with an elevated binding energy value .

CDK2-IN-22	CDK	Cancer
CDK2-IN-22 (compound 7I) is a potent *CDK2* inhibitor with an IC₅₀ of 64.42 nM. CDK2-IN-22 presents a broad antiproliferative efficacy toward diverse cancer cells MV4-11, HT-29, MCF-7, and HeLa with IC₅₀ values of 0.83 μM, 2.12 μM, 3.12 μM, and 8.61 μM, respectively .

CDK2-IN-8	CDK	Cancer
CDK2-IN-8 is a potent *CDK2* inhibitor with an IC₅₀ of 1.74 µM. CDK2-IN-8 shows antiproliferative activity. CDK2-IN-8 has the potential for the research of melanoma .

CDK2-IN-27	CDK	Cancer
CDK2-IN-27 (compound 1) is a potent *CDK2* inhibitor with IC₅₀ values of <10, >10-20 nM for CDK2/cyclin E1, CDK2/cyclin B1, respectively .

CDK2-IN-23	CDK	Cancer
CDK2-IN-23 (Compound 17) is a kinase selective and highly potent *CDK2* inhibitor (IC₅₀ = 0.29 nM). CDK2-IN-23 shows the pharmacodynamic inhibition of CDK2 in CCNE1-amplified mouse models. CDK2-IN-23 can be used for the research of cancer .

CDK2-IN-9	CDK Apoptosis	Cancer
CDK2-IN-9 is a potent *CDK2* inhibitor with an IC₅₀ of 0.63 µM. CDK2-IN-9 shows antiproliferative activity. CDK2-IN-9 induces apoptosis and cell cycle arrest at S and G2/M phase. CDK2-IN-9 has the potential for the research of melanoma .

CDK2-IN-13	CDK	Cancer
CDK2-IN-13 (Compound 15) is a *CDK2* inhibitor with an IC₅₀ of 12 µM. CDK2-IN-13 can be used in research of cancer .

CDK2-IN-14	CDK	Cancer
CDK2-IN-14 (compound 4f) is a highly selective *CDK2* inhibitor. CDK2-IN-14 can be used in research of cancer .

CDK2-IN-30	CDK	Cancer
CDK2-IN-30 (Formula (I)) is a *CDK2* inhibitor with an IC₅₀ value ≤20 nM. CDK2-IN-30 can be used in tumor research .

CDK2-IN-31	CDK	Cancer
CDK2-IN-31 (compound I-125A) is a *CDK2* inhibitor. CDK2-IN-31 can be used in cancer research .

CDK2-IN-7	CDK	Cancer
CDK2-IN-7 is a *CDK2* inhibitor for researching cancer (IC₅₀ < 50 nM).

CDK2-IN-26	CDK	Cancer
CDK2-IN-26 (compound 9) is a potent inhibitor of CDK2 .

CDK2-IN-19	CDK	Cancer
CDK2-IN-19 (Compound 32) is a selective and orally active *CDK2* inhibitor (K_i: 0.18 nM). CDK2-IN-19 shows anticancer activity in mice bearing OVCAR3 tumors .

CDK2-IN-12	CDK Carbonic Anhydrase	Cancer
CDK2-IN-12 (compound 10b) is a potent *CDK2* inhibitor, with an IC₅₀ of 11.6 μM. CDK2-IN-12 inhibits hCA (carbonic anhydrase) isoforms I, II, IX and XII, with K_I values of 3534, 638.4, 44.3, and 48.8 nM. CDK2-IN-12 shows anticancer activity .

CDK2-IN-3	CDK	Cancer
CDK2-IN-3 (compound 3) is a potent and selective *CDK2* inhibitor with an IC₅₀ of 60 nM .

CDK2-IN-32	CDK Apoptosis	Cancer
CDK2-IN-32 (Compound 5g) is a selective *CDK2* inhibitor with an IC₅₀ of 0.21 μM. CDK2-IN-32 shows cytotoxicity against Vero cells with an IC₅₀ of 28.52 μM .

CDK2-IN-25	CDK	Cancer
CDK2-IN-25 (compound 7e) is a CDK2 inhibitor with an IC₅₀ of 0.149 μM .

CDK2-IN-28	CDK	Cancer
CDK2-IN-28 (compound 22) is a *CDK2* inhibitor with good selectivity and cellular effects against other CDKs. CDK2-IN-28 has anti-proliferative effects on MKN1 cells (EC50: 0.31 μM) .

CDK2-IN-18	CDK	Cancer
CDK2-IN-18 (compound 8q) is a potent inhibitor of *CDK2/E* and *CDK4/D1, with IC₅₀s of 8 nM and 46 nM, respectively. CDK2*-IN-18 inhibits the proliferation of tumor cells .

CDK2-IN-4 2 Publications Verification	CDK	Cancer
CDK2-IN-4 (compound 73) is a potent and selective *CDK2* inhibitor with an IC₅₀ of 44 nM for CDK2/cyclin A, shows 2,000-fold selectivity over CDK1/cyclin B (IC₅₀=86 uM) .

CDK2/4-IN-1	CDK Microtubule/Tubulin	Cancer
CDK2/4-IN-1 (compound B-4a) is a *CDK2/4* inhibitor and a tubulin polymerization inhibitor. CDK2/4-IN-1 can be used in cancer research .

Cdk2/Cyclin Inhibitory Peptide I	CDK	Cancer
Cdk2/Cyclin Inhibitory Peptide I (Tat-LFG), a *CDK2* inhibitor, kills U2OS osteosarcoma cells in a dose-dependent manner .

Cdk2/Cyclin Inhibitory Peptide II	CDK	Cancer
Cdk2/Cyclin Inhibitory Peptide II (Tat-LDL), a *CDK2* inhibitor, kills U2OS osteosarcoma cells in a dose-dependent manner .

CDK2/Bcl2-IN-1	CDK	Cancer
CDK2/Bcl2-IN-1 (compound 1), a saponin and a CDK-2 inhibitor (IC₅₀=117.6 nM) with promising cytotoxicity against cancer cells. CDK2/Bcl2-IN-1 also inhibits Bcl-2, and induces apoptosis in A549 lung cancer cells .

CDK2-IN-29	CDK	Cancer
CDK2-IN-29 (Compound 13q) is an inhibitor for cyclin-dependent kinase (CDK), with IC₅₀ of 96 nM and 360 nM, for *CDK 2* and CDK 4, respectively .

CDK2/4/6-IN-2	CDK	Cancer
CDK2/4/6-IN-2 is a *CKD2/4/6* inhibitor, with IC₅₀ values less than 1 μM, 10 nM, 100 nM respectively .

CDK2AP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CDK2AP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK2AP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CDK2AP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CDK2AP2 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK2AP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

*PROTAC CDK2* Degrader-1**	PROTACs CDK	Cancer
PROTAC CDK2 Degrader-1 (Compound 41) is a PROTAC degrader for cyclin-dependent kinase 2 (CDK2). PROTAC CDK2 Degrader-1 inhibits the phosphorylation of RB protein in CDK2 dependent cell line OVCAR3 with an IC₅₀ of 100-500 nM .

*GSK-3/CDK5/CDK2-IN-1*	CDK GSK-3	Neurological Disease Cancer
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of *cdk5, cdk2, and GSK-3* extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases .

*EGFR/CDK2-IN-1*	EGFR CDK	Cancer
EGFR/CDK2-IN-1 (Compound 3b) is an *EGFR/CDK2* inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research .

*EGFR/CDK2-IN-2*	EGFR CDK	Cancer
EGFR/CDK2-IN-2 (compound 6a) is a dual inhibitor of EGFR and CDK-2 with IC₅₀s of 19.6 and 87.9 nM, respectively. EGFR/CDK2-IN-2 induces apoptosis in MCF-7 cells and arrests the cell cycle in the S phase. EGFR/CDK2-IN-2 has significant anti-cancer cell toxicity and inhibits MCF-7 with an IC₅₀ of 0.39 μM .

*EGFR/CDK2-IN-3*	EGFR CDK	Cancer
EGFR/CDK2-IN-3 (compound 4b) is a dual inhibitor of EGFR and CDK-2 with IC₅₀s of 71.7 and 113.7 nM, respectively. EGFR/CDK2-IN-3 induces apoptosis in MCF-7 cells and arrests the cell cycle in the S phase. EGFR/CDK2-IN-3 has significant anti-cancer cell toxicity and inhibits MCF-7 with an IC₅₀ of 3.16 μM .

Cat. No.	Product Name	Target	Research Area

HY-P0235

*CDK2*	Peptides	Cancer
CDK2 is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S₀/T₀) in a protein substrate.

HY-P3730

Cdk2/Cyclin Inhibitory Peptide I	CDK	Cancer
Cdk2/Cyclin Inhibitory Peptide I (Tat-LFG), a *CDK2* inhibitor, kills U2OS osteosarcoma cells in a dose-dependent manner .

HY-P10324

TAT-p16 p16^INK4a peptide	Peptides	Cancer
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .

Recombinant Proteins Recommended:

Cyclin-Dependent Kinase 2 (CDK2)

Species:	Human (8)
Tag:	His (10) SUMO (1) GST (7) Flag (6)
Source:	HEK293 (1) Sf9 insect cells (7) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P70014

	CDK2 Protein, Human (His) rHuCyclin-dependent kinase 2/CDK2, His; Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2	Human	E. coli
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2 Protein, Human (His) is the recombinant human-derived CDK2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDK2 Protein, Human (His) is 298 a.a., with molecular weight of 32-35 kDa.

HY-P702676

	CDK2-CCND1 Protein, Human (sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCND1 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK2-CCND1, expressed by Sf9 insect cells , with N-His, N-GST, N-Flag labeled tag. ,

HY-P71531

	SKP2 Protein, Human (His-SUMO) CDK2/Cyclin A associated protein p45; Cyclin A/CDK2 associated protein p45; Cyclin-A/CDK2-associated protein p45; F box protein Skp2; F box/LRR repeat protein 1; F-box protein Skp2; F-box/LRR-repeat protein 1; FBL 1; FBL1; FBXL 1; FBXL1; FLB 1; FLB1; MGC1366; p45; p45skp2	Human	E. coli
	SKP2 serves as a substrate recognition component in the SCF E3 ubiquitin-protein ligase complex, directing ubiquitination and proteasomal degradation of key proteins in the cell cycle, signaling, and transcription. It crucially recognizes phosphorylated CDKN1B/p27kip and regulates the G1/S transition. SKP2 Protein, Human (His-SUMO) is the recombinant human-derived SKP2 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of SKP2 Protein, Human (His-SUMO) is 424 a.a., with molecular weight of ~63.8 kDa.

HY-P702675

	CDK2-CCNA2 Protein, Human (sf9, GST, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNA2 Protein, Human (sf9, GST, His) is the recombinant human-derived CDK2-CCNA2, expressed by Sf9 insect cells , with N-6*His, N-GST labeled tag. ,

HY-P702677

	CDK2-CCNE1 Protein, Human (sf9, GST, His, Flag) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNE1 Protein, Human (sf9, GST, His, Flag) is the recombinant human-derived CDK2-CCNE1, expressed by Sf9 insect cells , with N-His, N-GST, N-Flag labeled tag. ,

HY-P702678

	CDK2-CCNE2 Protein, Human (sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNE2 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK2-CCNE2, expressed by Sf9 insect cells , with N-His, N-GST, N-Flag labeled tag. ,

HY-P702679

	CDK2-CCNO Protein, Human (sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNO Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK2-CCNO, expressed by Sf9 insect cells , with N-GST, N-Flag, N-His labeled tag. ,

HY-P703459

	CDK2/CCNE2 Protein, Sus scrofa (Active, Sf9, GST, His, Flag) Cyclin-dependent kinase 2; Cell division protein kinase 2; CDK2; Sus scrofa; Pig; Kinase; Serine/threonine-protein kinase; Transferase; 2.7.11.22	Others	Sf9 insect cells
	CDK2/CCNE2 Protein, Sus scrofa (Active, Sf9, GST, His, Flag) is the recombinant CDK2/CCNE2, expressed by Sf9 insect cells , with His, GST, Flag labeled tag. ,

HY-P703475

	CDK2-CCNE1 Protein, Sus scrofa (Active, Sf9, GST, His, Flag) Cyclin-dependent kinase 2; Cell division protein kinase 2; CDK2; Sus scrofa; Pig; Kinase; Serine/threonine-protein kinase; Transferase; 2.7.11.22	Others	Sf9 insect cells

HY-P7850

	CDK2AP2 Protein, Human (HEK293, His) rHuCyclin-dependent kinase 2-associated protein 2/CDK2AP2, His; Cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; DOC-1R; CDK2AP2; DOC1R	Human	HEK293
	CDK2AP2 protein, a vital component of the NuRD complex, actively engages in chromatin remodeling. It inhibits G1/S phase transition by suppressing CDK2, impeding CDK2's interaction with cyclin E or A. Beyond cell cycle control, CDK2AP2 is crucial for ESC self-renewal, ensuring survival during differentiation, and regulates microtubule organization in metaphase II oocytes. Part of the NuRD complex, CDK2AP2 collaborates with proteins like MTA1, MTA2, HDAC1, and others, showcasing its multifaceted regulatory functions. CDK2AP2 Protein, Human (HEK293, His) is the recombinant human-derived CDK2AP2 protein, expressed by HEK293, with C-6*His labeled tag. The total length of CDK2AP2 Protein, Human (HEK293, His) is 126 a.a., with molecular weight of ~26.0 kDa.

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Source
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Cat. No.	Product Name	Chemical Structure

HY-151580S

CDK2-IN-14-d3
CDK2-IN-14-d₃ is a potent and selective CDK2 inhibitor. CDK2-IN-14-d₃ can be used in research of cancer[1].

HY-P10324

TAT-p16
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80076

	Cdk2 Antibody Cdc2 related protein kinase; CDC28; CDC2A; CDK 2; CDK1; CDK2; CDK2_HUMAN ; CDKN2; MPF; p33(CDK2) antibody	WB, ICC/IF, IHC-P, IP, FC	Human, Mouse, Rat
	Cdk2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 34 kDa, targeting to Cdk2. It can be used for WB,ICC/IF,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse,Rat.

HY-P80798

	*Phospho-CDK2* (Tyr15) Antibody** CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase	WB, IP	Human, Hamster, Rat
	Phospho-CDK2 (Tyr15) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 34 kDa, targeting to Phospho-CDK2 (Tyr15). It can be used for WB,IP assays with tag free, in the background of Human, Hamster, Rat.

HY-P81587

	SKP2 Antibody (YA1332) SKP2; FBXL1; S-phase kinase-associated protein 2; Cyclin-A/CDK2-associated protein p45; F-box protein Skp2; F-box/LRR-repeat protein 1; p45skp2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	SKP2 Antibody (YA1332) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1332), targeting SKP2, with a predicted molecular weight of 48 kDa (observed band size: 48 kDa). SKP2 Antibody (YA1332) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

HY-P82827

	*Phospho-CDK1/2 (Thr14) Antibody (YA2572)* CDKN2; p33(CDK2)	WB, IHC-P, IP	Human
	Phospho-CDK1/2 (Thr14) Antibody (YA2572) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2572), targeting Phospho-CDK1/2 (Thr14), with a predicted molecular weight of 34 kDa (observed band size: 34 kDa). Phospho-CDK1/2 (Thr14) Antibody (YA2572) can be used for WB, IHC-P, IP experiment in human background.

HY-P82229

	SKP1 Antibody (YA1974) SKP1; EMC19; OCP2; SKP1A; TCEB1L; S-phase kinase-associated protein 1; Cyclin-A/CDK2-associated protein p19; Organ of Corti protein 2; OCP-2; Organ of Corti protein II; OCP-II; RNA polymerase II elongation factor-like protein; SIII; Transcr	WB, ICC/IF	Human, Mouse, Rat
	SKP1 Antibody (YA1974) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1974), targeting SKP1, with a predicted molecular weight of 19 kDa (observed band size: 19 kDa). SKP1 Antibody (YA1974) can be used for WB, ICC/IF experiment in human, mouse, rat background.

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Free Sample	Yes No
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Cat. No.	Product Name		Classification

HY-122609

XO44 PF-6808472		Alkynes
XO44 (PF-6808472) is a broad-spectrum covalent kinase probe. XO44 can bind in *CDK2 and CDK*1 .

HY-148213

CDK2/4/6-IN-1		Alkynes
CDK2/4/6-IN-1(example 29) is a *CDK2/4/6* inhibitor with IC₅₀ values of 2.5, 23.7 and 44.3 nM for CDK2, CDK4 and CDK6, respectively. CDK2/4/6-IN-1 can be used in cancer research . CDK2/4/6-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-RS02374

CDK2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
CDK2 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02375

Cdk2 Mouse Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
Cdk2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdk2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02376

Cdk2 Rat Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
Cdk2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdk2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02378

CDK2AP1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
CDK2AP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK2AP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02379

CDK2AP2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
CDK2AP2 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK2AP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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