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Results for "

hydroxyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (1) ADC Linker (1) Adrenergic Receptor (1) Aldehyde Dehydrogenase (ALDH) (1) Antibiotic (2) Apoptosis (5) Autophagy (4) Bacterial (3) Bcl-2 Family (1) Biochemical Assay Reagents (39) Caspase (1) Cytochrome P450 (2) DNA/RNA Synthesis (3) Drug Metabolite (2) Endogenous Metabolite (13) Endonuclease (1) Ferroptosis (2) Fluorescent Dye (9) Fungal (2) Glutathione Peroxidase (1) Histone Methyltransferase (1) Isotope-Labeled Compounds (3) Ligands for Target Protein for PROTAC (1) Liposome (2) mAChR (1) MAGL (1) Na+/K+ ATPase (1) NF-κB (1) p38 MAPK (1) Parasite (3) PARP (1) Phospholipase (2) Prostaglandin Receptor (4) PROTACs (1) Reactive Oxygen Species (12) VD/VDR (2)
By Research Areas:	Cancer (34) Cardiovascular Disease (5) Endocrinology (6) Infection (7) Inflammation/Immunology (15) Metabolic Disease (19) Neurological Disease (6)
Click Chemistry:	Labeling and Fluorescence Imaging (1) DBCO (1) Azide (2)
Oligonucleotides:	Pegylated Lipids (1) Cationic Lipids (1) Polymers (5)

143

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0674B

*Dehydrocorydaline (hydroxyl)* 25+ Cited Publications 13-Methylpalmatine (hydroxyl)	Bcl-2 Family Caspase PARP p38 MAPK Parasite Autophagy	Infection Inflammation/Immunology Cancer
Dehydrocorydaline (13-Methylpalmatine) hydroxyl is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline hydroxyl elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline hydroxyl shows strong anti-malarial effects (IC50=38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.

HY-N9961

*2-Hydroxyl* emodin-1-methyl ether**	Others	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-132180A

Seco-DUBA	ADC Cytotoxin	Inflammation/Immunology Cancer
Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups, which can each be used for coupling to an antibody via a linker. Seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-N7014

Hydroxyl-γ-isosanshool	Others	Neurological Disease
Hydroxyl-γ-isosanshool is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils. Hydroxyl-γ-isosanshoo induces a numbing sensation .

HY-161973

Hydroxyl-ML-210	Ligands for Target Protein for PROTAC	Cancer
Hydroxyl-ML-210 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Hydroxyl-ML-210 can be used for synthesis ZX782 (HY-161972) .

HY-144245S

*5-Hydroxyl* ZLN005-d13**	Isotope-Labeled Compounds	Others
5-Hydroxyl ZLN005-d₁₃ is the deuterium labeled 5-Hydroxyl ZLN005[1]。

HY-N3289

Methyl 3,4,5-trimethoxycinnamate	Others	Others
Methyl 3,4,5-trimethoxycinnamate (Compound III) is a natural compound with hydroxyl radical-scavenging effects .

HY-W590547

(6-(4-Hydroxybutylamino)hexyl)carbamic undecyl	Biochemical Assay Reagents	Others
(6-(4-Hydroxybutylamino)hexyl)carbamic undecyl is a lipid with a terminal hydroxyl group, which is used to construct or modify lipid nanoparticles (LNP). (6-(4-Hydroxybutylamino)hexyl)carbamic undecyl can be used in drug delivery research .

HY-D0113

*7-Hydroxy-4-methyl-2(1H)-quinolone*	Reactive Oxygen Species	Others
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage .

HY-D1067

NIR dye-1	Fluorescent Dye	Others
NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .

HY-107259

*23S-Hydroxyl-11,15-dioxo-ganoderic acid DM* 23S-Hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic	Others	Others
23S-Hydroxyl-11,15-dioxo-ganoderic acid DM is a compound isolated from the fruit bodies of Ganoderma lucidum .

HY-121137

BMPO BocMPO	Others	Others
BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals .

HY-135152

CYPMPO	Reactive Oxygen Species	Cancer
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor?activity .

HY-N9095

Curculigoside C	Others	Neurological Disease
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Others	Metabolic Disease
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants of Ginkgo biloba leaves .

HY-Y0958

Methoxyamine hydrochloride O-Methylhydroxylamine hydrochloride	DNA/RNA Synthesis Apoptosis	Cancer
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents .

HY-113490

15-KETE	Others	Metabolic Disease
15-OxoETE is produced by oxidation of the 15-hydroxyl of 15-HETE.

HY-Y0958R

Methoxyamine hydrochloride (Standard)	DNA/RNA Synthesis Apoptosis	Cancer
Methoxyamine (hydrochloride) (Standard) is the analytical standard of Methoxyamine (hydrochloride). This product is intended for research and analytical applications. Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents .

HY-D1159

HKOH-1r 4 Publications Verification	Reactive Oxygen Species Fluorescent Dye	Others
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-18408

5S rRNA modificator FAI	Biochemical Assay Reagents	Others
5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification.

HY-D0913

1-Methyl-7-nitroisatoic anhydride 2 Publications Verification 1M7	Fluorescent Dye	Others
1-methyl-7-nitroisatoic anhydride (1M7) is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity, can be used for RNA structure analysis .

HY-P2863

Deoxyribonuclease II DNase II	Endonuclease	Others
Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research .

HY-100592

Nicaraven 2 Publications Verification	Others	Cancer
Nicaraven is a novel chemically synthesized hydroxyl radical-specific scavenger.

HY-E70241

3-Hydroxypropionyl-CoA	Others	Others
3-Hydroxypropionyl-CoA is a derivative of coenzyme A containing a hydroxyl group .

HY-P2844

Polynucleotide kinase	DNA/RNA Synthesis	Metabolic Disease
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .

HY-W440891

DSPE-PEG-OH (MW 1000)	Biochemical Assay Reagents	Others
DSPE-PEG-OH, MW 1000 is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound. Reagent grade, for research use only.

HY-D1395

RH-EDA	Reactive Oxygen Species	Others
RH-EDA is a rhodamine-based turn-on fluorescent probe for detecting hydroxyl radicals in living systems.

HY-P4280

Arg-Tyr	Reactive Oxygen Species	Others
Arg-Tyr is a dipeptide which has strong hydroxyl-radical and hydrogen-peroxide scavenging activity .

HY-N9497

Galactinol	Biochemical Assay Reagents	Others
Galactinol is a biochemical reagent. Galactinol scavenges hydroxyl radicals and protects plant cells from oxidative damage .

HY-135580

Raloxifene Bismethyl Ether	Drug Metabolite	Endocrinology
Raloxifene Bismethyl Ether is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent .

HY-135580A

Raloxifene Bismethyl Ether hydrochloride	Drug Metabolite	Endocrinology
Raloxifene Bismethyl Ether hydrochloride is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent .

HY-W683499

Lauryl hydroxysultaine LHSB	Biochemical Assay Reagents	Others
Lauryl hydroxysultaine (LHSB), a surfactant, is comprised of a core Sultaine structure with a sulphopropyl quaternary ammonium salt, an alkyl group and a hydroxyl group .

HY-D1151

HKOH-1	Reactive Oxygen Species Fluorescent Dye	Others
HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-N8737

Desrhamnosylmartynoside	Others	Others
Desrhamnosylmartynosideis extracted from the root of Scutellaria prostrata. Desrhamnosylmartynoside has absorption bands assignable to hydroxyl,α,β-unsanturate carbonyl groups .

HY-15157

Calcitetrol 1α, 24, 25-Trihydroxy VD3	VD/VDR	Metabolic Disease
Calcitetrol(1α, 24, 25-Trihydroxy VD3) is the hormonally active form of vitamin D with three hydroxyl groups.

HY-125607

Tetranor-PGJM	Prostaglandin Receptor	Inflammation/Immunology
Tetranor-PGJM is a metabolite of prostaglandin-D2, which formed by the elimination of the C-9 hydroxyl group, is related to the inflammatory efficacy of curcuma .

HY-151822

Hydroxy-PEG3-DBCO	ADC Linker	Others
Hydroxy-PEG3-DBCO is a click chemistry reagent containing an azide group. Hydroxy-PEG3-DBCO is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .

HY-130025

HKOCl-3 2 Publications Verification	Fluorescent Dye	Others
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.E_x: 490 nm; E_m 527 nm .

HY-122761

Quifenadine	mAChR	Neurological Disease
Quifenadine (Compound 3a), the hydroxyl-(diphenyl)methyl quinuclidine derivative, is a M3 receptor antagonist with an IC₅₀ value > 1000 nM. Quifenadine can be used for the research of neurological disease .

HY-N9332

Kalopanax saponin G	Others	Others
Kalopanax saponin G is an ester glycoside of oleanolic acid possessing no sugar moiety at the C-3 hydroxyl group. Kalopanax saponin G is isolated from the bark of Kalopanax pictus .

HY-135258

Galactinol dihydrate	Others	Others
Galactinol dihydrate is a marker for seed longevity. Galactinol dihydrate can scavenge hydroxyl radicals and protect plant cells from oxidative damage caused by MV treatment, salinity, or chilling .

HY-N13179

Wilforic acid A	Others	Others
Wilforic acid A is a triterpene compound that can be isolated from the Tripterygium wilfordii. Wilforic acid A shows a hydroxyl absorption band at 3402 cm ^-1 and a carbonyl absorption band at 1702 cm ^-1 .

HY-103006

NAI-N3 5 Publications Verification	Biochemical Assay Reagents	Others
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-116141

7-Hydroxycoumarinyl arachidonate 7-HCA; Umbelliferyl Arachidonate; 7-HC-arachidonate	Phospholipase MAGL	Others
7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer .

HY-118830

13,14-Dihydro-15-keto prostaglandin D2 DK-PGD2; 15-Oxo-13,14-dihydro-PGD2; 13,14-Dihydro-15-keto-PGD2	Prostaglandin Receptor	Endocrinology
13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation .

HY-164071

Carboxymethyl Dextran (CM-Dextran)	Biochemical Assay Reagents	Others
Carboxymethyl Dextran (CM-Dextran) is a dextran with carboxymethyl substituted hydroxyl groups. It has good hydrophilicity and ionic properties and can be used as a biomaterial or organic compound for life science related research .

HY-165078

(±)11(12)-EpETE (±)11,12-EEQ; (±)11,12-Epoxyeicosatetraenoic acid	Others	Others
(±)11(12)-EpETE ((±)11,12-EEQ) is an EPA hydroxyl product. EPA is a major component of Omega-3 polyunsaturated fatty acids (PUFAs) .

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

HY-B0684

Iopamidol 3 Publications Verification B-15000; SQ-13396	Biochemical Assay Reagents	Cancer
Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .

HY-E70040

Endoglycoceramidase I (EGCase I)	Endogenous Metabolite	Metabolic Disease
Endoglycoceramidase I (EGCase I) is a glycosidase, is often used in biochemical studies. Endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of GSLs to the primary hydroxyl group of several 1-alkanols .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0674B

*Dehydrocorydaline (hydroxyl)* 25+ Cited Publications 13-Methylpalmatine (hydroxyl)	Structural Classification Alkaloids Corydalis yanhusuo W. T. Wang Source classification Plants Papaveraceae	Bcl-2 Family Caspase PARP p38 MAPK Parasite Autophagy
Dehydrocorydaline (13-Methylpalmatine) hydroxyl is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline hydroxyl elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline hydroxyl shows strong anti-malarial effects (IC50=38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.

HY-N9961

*2-Hydroxyl* emodin-1-methyl ether**	Quinones Structural Classification Cassia obtusifolia L. Anthraquinones Source classification Caesalpiniaceae Plants	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Flavonols Flavonoids Classification of Application Fields Ginkgoaceae Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Ginkgo biloba	Others
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants of Ginkgo biloba leaves .

HY-N7014

Hydroxyl-γ-isosanshool	Natural Products Source classification Myrtaceae Plants Syzygium aromaticum	Others
Hydroxyl-γ-isosanshool is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils. Hydroxyl-γ-isosanshoo induces a numbing sensation .

HY-N3289

Methyl 3,4,5-trimethoxycinnamate	Structural Classification Natural Products Source classification Plants Brassicaceae Mutarda nigra (L.) Bernh.	Others
Methyl 3,4,5-trimethoxycinnamate (Compound III) is a natural compound with hydroxyl radical-scavenging effects .

HY-107259

*23S-Hydroxyl-11,15-dioxo-ganoderic acid DM* 23S-Hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic	Triterpenes Classification of Application Fields Terpenoids Source classification Polyporaceae Other Diseases Plants Disease Research Fields	Others
23S-Hydroxyl-11,15-dioxo-ganoderic acid DM is a compound isolated from the fruit bodies of Ganoderma lucidum .

HY-N9095

Curculigoside C	Curculigo orchioides Gaertn. Structural Classification Source classification Phenols Polyphenols Plants Amaryllidaceae	Others
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-N8737

Desrhamnosylmartynoside	Structural Classification Monophenols Labiatae Source classification Phenols Plants Seriphidium transiliense	Others
Desrhamnosylmartynosideis extracted from the root of Scutellaria prostrata. Desrhamnosylmartynoside has absorption bands assignable to hydroxyl,α,β-unsanturate carbonyl groups .

HY-N9332

Kalopanax saponin G	Structural Classification Polysaccharides Classification of Application Fields Kalopanax septemlobus (Thunb.) Koidz. Source classification Other Diseases Plants Disease Research Fields Saccharides Araliaceae	Others
Kalopanax saponin G is an ester glycoside of oleanolic acid possessing no sugar moiety at the C-3 hydroxyl group. Kalopanax saponin G is isolated from the bark of Kalopanax pictus .

HY-N13179

Wilforic acid A	Triterpenes Structural Classification Terpenoids Source classification Celastraceae Tripterygium wilfordii Hook. f. Plants	Others
Wilforic acid A is a triterpene compound that can be isolated from the Tripterygium wilfordii. Wilforic acid A shows a hydroxyl absorption band at 3402 cm ^-1 and a carbonyl absorption band at 1702 cm ^-1 .

HY-136933

Gitoxin	Digitalis purpurea Linn. Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Scrophulariaceae Plants Disease Research Fields Steroids	Na+/K+ ATPase
Gitoxin, a Na ⁺/K ⁺-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably .

HY-N2627

Isorhamnetin 3-O-robinobioside	Structural Classification Flavonoids Cactaceae Flavones Source classification Opuntia ficus-indica (L.) Mill. Plants	Others
Isorhamnetin 3-O-robinobioside is a flavonoid compound. Isorhamnetin shows a protective effect against lipid peroxidation induced by H₂O₂. Isorhamnetin 3-O-robinobioside also inhibits the genotoxicity induced by hydroxyl radicals .

HY-N2625A

Harmalol hydrochloride	Alkaloids Structural Classification Monophenols Classification of Application Fields Zygophyllaceae Peganum harmala Linn. Source classification Other Diseases Phenols Pyridine Alkaloids Plants Disease Research Fields	Cytochrome P450
Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties .

HY-107486

Nosiheptide Multhiomycin; RP 9671	Infection Structural Classification Microorganisms Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .

HY-151852

9AzNue5Ac	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
9AzNue5Ac, 9-azido-9-deoxy-N-acetylneuraminic acid, is a click chemistry reagent and a Neu5Ac analogue with the substitution of 9-hydroxyl group with an azide. 9AzNue5Ac could be metabolized and incorporated into sialoglycans in living cells and mice. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-137566

Cucumarioside H	Triterpenes Structural Classification Animals Terpenoids Source classification	Others
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.

HY-N0828

Pterostilbene 5 Publications Verification	Structural Classification Monophenols other families Stilbenes Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Autophagy
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

HY-N2625AR

Harmalol hydrochloride (Standard)	Alkaloids Structural Classification Monophenols Zygophyllaceae Peganum harmala Linn. Source classification Phenols Pyridine Alkaloids Plants	Cytochrome P450
Harmalol (hydrochloride) (Standard) is the analytical standard of Harmalol (hydrochloride). This product is intended for research and analytical applications. Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties .

HY-107486R

Nosiheptide (Standard)	Structural Classification Microorganisms Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Other Antibiotics	Bacterial Antibiotic
Nosiheptide (Standard) is the analytical standard of Nosiheptide. This product is intended for research and analytical applications. Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .

HY-W027951

N,N'-Dimethylthiourea DMTU	Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Allium sativum Linn. Plants Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species
N,N'-Dimethylthiourea (DMTU), isolated from Allium sativum, is an orally active scavenger of hydroxyl radical (•OH) and blocks •OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats by exerting its antioxidant action including •OH scavenging and anti-inflammatory action .

HY-134493

Butyrate-Vitamin D3 Butyrate-Cholecalciferol; Butyrate-Colecalciferol	Structural Classification Natural Products Source classification Endogenous metabolite	VD/VDR
Butyrate-Vitamin D3 (Butyrate-Cholecalciferol) is a derivative of vitamin D3 in which a hydroxyl group in the vitamin D3 molecule is replaced by a butyric acid group. Butyrate-Vitamin D3 affects gene expression and cell function and has certain anti-inflammatory effects. Butyrate-Vitamin D3 can be used in the study of immune regulation, metabolic diseases and cancer .

HY-125400

Zaragozic acid C L-697350	Structural Classification Natural Products Microorganisms Source classification	Endogenous Metabolite
Zaragozic acid C (L-697350) is a potent sterol synthase inhibitor with potential antitumor activity. Zaragozic acid C contains multiple hydroxyl and alkyl substituents in its chemical structure, demonstrating complex functionalization capabilities. The synthesis of zaragozic acid C involves a photochemical C(sp3)-H acylation reaction, which resolves the challenging carbon substitution problem in the synthesis .

HY-W015788

1-Phenylethane-1,2-diol Styrene Glycol	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields	Others
1-Phenylethane-1,2-diol is a typical benzyl diol compound. 1-Phenylethane-1,2-diol can be oxidized to hydroxyl ketone (2-hydroxy-1-phenylethan-1-one) selectively with variety of catalysts, including organocatalysts, metal complexes, non-noble metal oxides, bimetallics .

HY-E70007

Catechol O-methyltransferase, porcine liver COMT	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Catechol O-methyltransferase, porcine liver (COMT), the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain .

HY-118118

Phlebiakauranol aldehyde	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .

HY-N0828R

Pterostilbene (Standard)	Structural Classification Monophenols other families Stilbenes Source classification Phenols Plants	Autophagy
Pterostilbene (Standard) is the analytical standard of Pterostilbene. This product is intended for research and analytical applications. Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

HY-W021265

Cyclohexane-1,2,3,4,5,6-hexaol Cyclohexane-1,2,3,4,5,6-hexol	Microorganisms Source classification	Biochemical Assay Reagents
Cyclohexane-1,2,3,4,5,6-hexaol, also known as inositol or inositol, is a cyclic sugar alcohol consisting of a six-carbon ring with six hydroxyl groups. This compound is important for its biological activity and is widely distributed in nature, especially in plant and animal tissues. It plays a role in various physiological processes such as signal transduction, osmoregulation and lipid metabolism. In addition, Cyclohexane-1,2,3,4,5,6-hexaol has potential investigational effects, including improving conditions related to insulin resistance, polycystic ovary syndrome, and mental health conditions. It can also be used as a supplement in animal feed and human nutritional products.

HY-N13081

3-Oxo-cinobufagin	Structural Classification Microorganisms Source classification Steroids	Others
3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagin's cytotoxicity against cancer cells are: 71.3 μM (HepG2), 90.2 μM (SMMC-7221), 0.11 μM (BEL-7402), 72.5 μM (K562), 5.3 μM (HL-60), and 12 nM (HEL) .

HY-W015229R

3-Indolepropionic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Reactive Oxygen Species
3-Indolepropionic acid (Standard) is the analytical standard of 3-Indolepropionic acid. This product is intended for research and analytical applications. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. In Vitro: 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease . 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds . It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function .

Cat. No.	Product Name	Chemical Structure

HY-144245S

*5-Hydroxyl* ZLN005-d13**
5-Hydroxyl ZLN005-d₁₃ is the deuterium labeled 5-Hydroxyl ZLN005[1]。

HY-112537S2

D-Glucose 6-phosphate-13C
D-Glucose 6-phosphate-13C is ¹³C labeled D-Glucose 6-phosphate (HY-112537). D-Glucose 6-phosphate is glucose phosphorylated with a hydroxyl group on carbon 6 .

HY-B0684S

Iopamidol-d8
Iopamidol-d₈ (B-15000-d8) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast[1].

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