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solid

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320

Inhibitors & Agonists

2

Screening Libraries

25

Fluorescent Dye

28

Biochemical Assay Reagents

16

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43

Inhibitory Antibodies

17

Natural
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6

Isotope-Labeled Compounds

2

Click Chemistry

5

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111786

    Toll-like Receptor (TLR) Cancer
    LHC-165 is a TLR7 agonist. LHC-165 has potential to used in study of solid tumors .
    LHC-165
  • HY-137435
    Cirtuvivint
    1 Publications Verification

    SM08502

    CDK Cancer
    Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor. Cirtuvivint can be used for solid tumors research .
    Cirtuvivint
  • HY-P99271

    Anti-Human F3 Recombinant Antibody

    ADC Antibody Cancer
    Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody and ADC antibody. Tisotumab targets tissue factor (TF). Tisotumab can be used for the research of solid tumors .
    Tisotumab
  • HY-23408

    PROTAC Linkers Cancer
    Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports .
    Tos-PEG3
  • HY-137457A

    IDX-1197 hydrochloride

    PARP Cancer
    Venadaparib (IDX-1197) hydrochloride is a potent and selective PARP inhibitor with anticancer activities. Venadaparib hydrochloride can be used for solid tumors research .
    Venadaparib hydrochloride
  • HY-168392

    Biochemical Assay Reagents Others
    Propylene glycol monopalmitate can be used to synthesize solid lipid nanoparticles (SLNs) for the delivery of bioactive compounds .
    Propylene glycol monopalmitate
  • HY-P99887

    JTX-4014

    PD-1/PD-L1 Cancer
    Pimivalimab (JTX-4014) is a PD-1 inhibitor. Pimivalimab can be used for the research of solid tumor .
    Pimivalimab
  • HY-105529

    (+)-Indicine N-oxide; NSC 132319

    Microtubule/Tubulin Cancer
    Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research .
    Indicine N-oxide
  • HY-161249

    Pantetheinase Inflammation/Immunology
    Vanin-1-IN-4 (compound (S)-1) is vanin-1 inhibitor with a chiral methyl substituent, with profils as potent drug-candidate but exist as an amorphous solid .
    Vanin-1-IN-4
  • HY-112516

    Amino Acid Derivatives Others
    Fmoc-Lys(amino aldehyde)-Boc is a lysine derivative, and is very sensitive to acid and heat. Fmoc-Lys(amino aldehyde)-Boc and can be used in solid phase synthesis .
    Fmoc-Lys(amino aldehyde)-Boc
  • HY-P10893

    Drug Derivative Cancer
    BCY8234 is a mono-methylauristatin E (MMAE)-free analogue of BT8009. BT8009 is a nectin-4 targeting bicycle toxin conjugate for the treatment of solid tumors. BCY8234 attenuates the response to BT8009 .
    BCY8234
  • HY-W016413

    Biochemical Assay Reagents Others
    4-(Hydroxymethyl)phenoxyacetic acid is an acid-labile resin linkage agent for use in solid phase peptide synthesis .
    4-(Hydroxymethyl)phenoxyacetic acid
  • HY-P3448

    CEND-1; iRGD; LSTA1

    Integrin Complement System Cancer
    Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors .
    Certepetide
  • HY-169129

    ILX-295501

    Drug Derivative Cancer
    LY-295501 is a sulfonylurea compound that has demonstrated in-vivo antitumor activity against a broad spectrum of solid tumors. LY-295501 can be utilized in cancer research .
    LY-295501
  • HY-P99489

    ABBV 181; PR 1648817

    PD-1/PD-L1 Cancer
    Budigalimab (ABBV 181; PR 1648817) is a humanized, recombinant IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. Budigalimab has an Fc mutation that reduces the inhibition of Fc receptor interactions and effector factors. Budigalimab can block the binding of PD-1 and PD-L1, which has anti-tumor activity. Budigalimab can be used in the study of solid tumors .
    Budigalimab
  • HY-137457
    Venadaparib
    1 Publications Verification

    IDX-1197

    PARP Cancer
    Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research .
    Venadaparib
  • HY-160289

    Proteasome Cancer
    ARI-3144 is an excellent substrate for fibroblast activation protein (FAP). ARI-3144 is a FAP-activated proteasome inhibitor that can be used for the research of solid tumors .
    ARI-3144
  • HY-153243

    c-Fms Cancer
    IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research .
    IACS-9439
  • HY-N10300

    Fungal Infection
    Guignardone K is a meroterpene compound isolated from solid cultures of the endophytic fungus Guignardia sp.. Guignardone K has antifungal activity .
    Guignardone K
  • HY-117220

    Others Cancer
    Aspochalasin M is a colorless solid. Aspochalasin M shows modest activity against HL-60 cells with an IC50 of 20.0 μM. Aspochalasin M has the potential for the research of leukemic disease .
    Aspochalasin M
  • HY-P99708

    ABBV-151; ARGX-115

    TGF-beta/Smad Cancer
    Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors .
    Livmoniplimab
  • HY-170393

    JAK STAT Cancer
    iBFAR2, a BFAR inhibitor, restores the CD8+ TRM cell subset against solid tumors. iBFAR2 promotes JAK2-STAT1 association and STAT1 phosphorylation .
    iBFAR2
  • HY-128587
    Mevociclib
    4 Publications Verification

    SY-1365

    CDK Cancer
    Mevociclib (SY-1365) is a potent and first-in-class selective CDK7 inhibitor, with a Ki of 17.4 nM. Mevociclib exhibits anti-proliferative and apoptotic effects in solid tumor cell lines. Mevociclib possesses anti-tumor activity in hematological and multiple aggressive solid tumors .
    Mevociclib
  • HY-D0177

    Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

    Biochemical Assay Reagents Others
    (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and can be utilized in solid phase synthesis test .
    (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
  • HY-P99785

    HLX20

    PD-1/PD-L1 Cancer
    Opucolimab is an anti-PD-L1 recombinant human monoclonal antibody. Opucolimab can be used to synthesis antibody agent conjugates. Opucolimab can be used for the research of advanced solid tumors .
    Opucolimab
  • HY-128470

    GR-30921

    Drug Derivative Cancer
    Mitoquidone (GR-30921) is is the first member of a group of pentacyclic pyrroloquinones. Mitoquidone shows good activity in a range of experimental solid tumour models. Mitoquidone can be used for the research of anti-cancer .
    Mitoquidone
  • HY-19095

    Antifolate Cancer
    TNP-351 is an antifolate. TNP-351, a dihydrofolate reductase (DHFR) inhibitor, has potent antitumor activity against not only leukemia cells but also solid tumor cells in vitro and in vivo .
    TNP-351
  • HY-13554

    Antibiotic Infection Cancer
    Annamycin is an antibiotic, that has high affinity for lipid membranes and can bypass the multidrug resistance protein-1 (MDR-1 ) mechanism of cellular drug resistance. Annamycin exhibits antitumor efficacy in multilamellar vesicles against solid tumor .
    Annamycin
  • HY-139453A

    DNA Alkylator/Crosslinker Cancer
    LP-284 is a potent DNA alkylating agent that kills solid tumours. LP-284 can be used in the studies of hematologic cancers with compromised DNA repair, such as mantle cell lymphoma (MCL) .
    LP-284
  • HY-16110

    UFT; BMS-200604

    Thymidylate Synthase Cancer
    Tegafur-Uracil (UFT; BMS-200604) is an effective oral chemotherapy drug based on fluoropyrimidine. Tegafur-Uracil inhibits thymidylate synthase. Tegafur-Uracil can be used in combination with leucovorin (LV) and polysaccharide K (PSK) for research on solid tumors .
    Tegafur-Uracil
  • HY-125924
    DSPE-PEG-Amine, MW 2000 ammonium
    1 Publications Verification

    DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium

    Liposome Others
    DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
    DSPE-PEG-Amine, MW 2000 ammonium
  • HY-10058

    JAK Aurora Kinase Bcr-Abl FLT3 Apoptosis Autophagy Cancer
    AT9283 lactic acid is a multi-targeted kinase inhibitor with potent activity against Aurora A/B, JAK2/3, Abl (T315I) and Flt3 (IC50s ranging from 1 to 30 nM). AT9283 lactic acid inhibits growth and survival of multiple solid tumors in vitro and in vivo .
    AT9283 lactic acid
  • HY-101266B
    Milademetan tosylate hydrate
    5 Publications Verification

    DS-3032b; DS-3032 tosylate hydrate

    MDM-2/p53 E1/E2/E3 Enzyme Apoptosis Cancer
    Milademetan (DS-3032) tosylate hydrate is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis .
    Milademetan tosylate hydrate
  • HY-101266
    Milademetan
    5 Publications Verification

    DS-3032

    MDM-2/p53 E1/E2/E3 Enzyme Apoptosis Cancer
    Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis .
    Milademetan
  • HY-13892

    CHIR-258 dilactic acid; TKI258 dilactic acid

    VEGFR Cancer
    Dovitinib (dilactic acid) is an orally active inhibitor of VEGF kinase. Dovitinib (dilactic acid) inhibits receptor tyrosine kinases (RTKs) involved in solid and hematologic cancers and tumor angiogenesis .
    Dovitinib dilactic acid
  • HY-142118A

    AP 12009 sodium

    TGF-beta/Smad Cancer
    Trabedersen sodium is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen sodium can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon .
    Trabedersen sodium
  • HY-135737
    Dicaprylyl carbonate
    1 Publications Verification

    Dioctyl carbonate

    Biochemical Assay Reagents Others
    Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .
    Dicaprylyl carbonate
  • HY-142118

    AP 12009

    TGF-beta/Smad Cancer
    Trabedersen (AP 12009) is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon .
    Trabedersen
  • HY-W164451

    Fungal Infection
    N-(2-hydroxy-2-phenylethyl)acetamide is isolated from the solid rice cultures of the endophytic fungus Diaporthe eucalyptorum KY-9. N-(2-hydroxy-2-phenylethyl)acetamide exhibits antifungal activities against Alternaria solani .
    N-(2-hydroxy-2-phenylethyl)acetamide
  • HY-P99450

    IPH 5401; Anti-C5aR1 mAb

    Complement System Inflammation/Immunology Cancer
    Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research .
    Avdoralimab
  • HY-P99475

    MSB-2311

    PD-1/PD-L1 Cancer
    Betifisolimab (MSB-2311) is a humanized monoclonal antibody directed against the immunosuppressive ligand PD-L1. Betifisolimab has the potential for advanced solid tumors and hematological malignancies research .
    Betifisolimab
  • HY-P99827

    TSR-022; GSK4069889

    Tim3 Cancer
    Cobolimab (TSR-022) is an anti-TIM-3 monoclonal antibody. Cobolimab mediates the internalization of TIM3 with an IC50 value of 0.4464 nM. Cobolimab has potential application in solid tumors and non-small cell lung cancer (NSCLC) .
    Cobolimab
  • HY-162858

    Caspase Cancer
    BRD-810 is a highly selective MCL1 inhibitor. BRD-810 can bind to the BH3 groove of MCL1 and block the sequestration of pro-apoptotic proteins, quickly inducing caspase activation in MCL1-dependent cell lines. BRD-810 shows anti-tumor activity in models of blood cancers and solid tumors .
    BRD-810
  • HY-W012184

    Biochemical Assay Reagents Inflammation/Immunology
    CDAP is an organic cyanylating reagent that can be used for preparation of solid phase affinity reagents, modification of protein thiols and nucleotide delivery. CDAP also activates polysaccharides with a variety of chemical properties. CDAP can be used to prepare conjugate vaccines and other immune reagents .
    CDAP
  • HY-144424

    Trk Receptor Cancer
    Trk-IN-11 (Compound 14h) is a potent inhibitor of TRK (IC50 = 1.4, 1.8 nM, against TrkA, TrkA G595R, respectively). As a receptor tyrosine kinase (RTK), tropomyosin receptor kinase (Trk) is a key agent target in solid tumors. Trk-IN-11 has the potential for the research of cancer disease .
    Trk-IN-11
  • HY-164493

    Ras Cancer
    KRASG12C IN-13 (LY3499446) is a potent KRAS G12C inhibitor. KRASG12C IN-13 is promising for research of advanced solid tumors including non-small cell lung cancer and colorectal cancer .
    KRASG12C IN-13
  • HY-101566A
    Elimusertib hydrochloride
    5+ Cited Publications

    BAY 1895344 hydrochloride

    ATM/ATR Cancer
    Elimusertib (BAY 1895344) hydrochloride is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib hydrochloride has anti-tumor activity . Elimusertib hydrochloride can be used for the research of solid tumors and lymphomas .
    Elimusertib hydrochloride
  • HY-101566
    Elimusertib
    5+ Cited Publications

    BAY 1895344

    ATM/ATR Cancer
    Elimusertib (BAY-1895344) is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib has anti-tumor activity . Elimusertib can be used for the research of solid tumors and lymphomas .
    Elimusertib
  • HY-106218

    5-Fluorocyclocytidine; 5'-Fluorocyclocytidine

    Nucleoside Antimetabolite/Analog Cancer
    Flurocitabine (5-Fluorocyclocytidine) is a fluorinated anlydride analog of cytosine arabinoside, partially hydrolysecl in vivo into two active antitumor substances (arabinosyl-tluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU)). Flurocitabine (5-Fluorocyclocytidine) has antitumor activity during phase I studies in acute leukemia and solid tumors .
    Flurocitabine
  • HY-P99217

    AMG 102

    c-Met/HGFR Cancer
    Rilotumumab (AMG 102) is an anti-HGF (anti-hepatocyte growth factor) monoclonal antibody, inhibits HGF/MET-driven signaling. Rilotumumab shows anti-tumor activity, and can be used in castration-resistant prostate cancer (CRPC) and solid tumor research .
    Rilotumumab

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