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Results for "

-SH

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) ADC Linker (1) Adenosine Receptor (1) Akt (1) Amyloid-β (12) Anaplastic lymphoma kinase (ALK) (1) Antibiotic (2) Apoptosis (19) Arenavirus (2) Atg8/LC3 (2) Autophagy (10) Bacterial (3) Bcl-2 Family (1) Bcr-Abl (1) Beta-secretase (1) Biochemical Assay Reagents (12) BMI1 (1) Carbonic Anhydrase (1) Casein Kinase (1) Caspase (2) CCR (1) CDK (1) Cholinesterase (ChE) (11) Deubiquitinase (1) DNA Stain (1) Dopamine Receptor (1) Drug-Linker Conjugates for ADC (1) EGFR (2) Endogenous Metabolite (5) ERK (3) Estrogen Receptor/ERR (1) FAAH (2) Fluorescent Dye (6) Fungal (3) Glycosidases (1) GSK-3 (2) HDAC (1) Histamine Receptor (1) HIV (2) IFNAR (2) iGluR (1) Interleukin Related (2) Isocitrate Dehydrogenase (IDH) (1) Keap1-Nrf2 (4) Ligands for Target Protein for PROTAC (1) Liposome (1) MAGL (1) Mitochondrial Metabolism (2) Monoamine Oxidase (6) mTOR (2) Na+/Ca2+ Exchanger (3) NAMPT (1) Necroptosis (2) Neuropeptide Y Receptor (1) OGA (1) Oxidative Phosphorylation (1) p62 (2) Parasite (1) PARP (2) Phosphatase (5) Phosphodiesterase (PDE) (1) PI3K (4) PIN1 (1) Polo-like Kinase (PLK) (1) PROTAC Linkers (22) PROTACs (1) Reactive Oxygen Species (2) SHP2 (3) Sigma Receptor (2) Sirtuin (1) Small Interfering RNA (siRNA) (32) Src (7) STAT (20) Syk (1) Tau Protein (2) Thyroid Hormone Receptor (2) TNF Receptor (4) Tyrosinase (1) γ-secretase (2)
By Research Areas:	Cancer (85) Cardiovascular Disease (6) Endocrinology (4) Infection (6) Inflammation/Immunology (17) Metabolic Disease (8) Neurological Disease (55)
Click Chemistry:	DBCO (1) PROTAC Synthesis (4) Alkynes (5)
Oligonucleotides:	Pegylated Lipids (1) Pre-designed siRNA Sets (32) Polymers (5) siRNAs (32)

207

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
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Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-143228

SH-42	Others	Cardiovascular Disease Inflammation/Immunology Cancer
SH-42 is a potent and selective inhibitor of human Δ ²⁴-dehydrocholesterol reductase (DHCR24), with an IC₅₀ of 42 nM. SH-42 can lead to a significant increase in plasma desmosterol levels of mice .

HY-16975

SH-4-54 10+ Cited Publications	STAT	Cancer
SH-4-54 is a STAT inhibitor that binds to STAT3 and STAT5 with K_Ds of 300, 464 nM, respectively.

HY-100494

SH5-07 1 Publications Verification	STAT	Cancer
SH5-07 is a hydroxamic acid based Stat3 inhibitor with an IC₅₀ of 3.9 μM in in vitro assay .

HY-124758

SH-BC-893	Mitochondrial Metabolism	Metabolic Disease Cancer
SH-BC-893 is an orally active anti-neoplastic sphingolipid analog. SH-BC-893 also protects from ceramide-induced mitochondrial dysfunction and corrects diet-induced obesity. SH-BC-893 can be used for the research of cancer and obesity .

HY-100702

SH-5	Akt Apoptosis	Cancer
SH-5 is a potent AKT inhibitor. SH-5 potentiates the apoptosis induced by tumor necrosis factor. SH-5 blocks NF-kB activation induced by TNF-a, lipopolysaccharide (HY-D1056), phorbol ester (HY-18739), and cigarette smoke .

HY-139920A

Oritinib mesylate SH-1028 mesylate	EGFR	Cancer
Oritinib (SH-1028) mesylate is a selective, orally active, and pyrimidine-based irreversible inhibitor of EGFR with an IC₅₀ of 18 nM. Oritinib (SH-1028) mesylate exhibits potent activity against EGFR sensitive and resistant (T790 M) mutations. Oritinib (SH-1028) mesylate significantly inhibits proliferation of tumor cells with EGFR sensitive and resistant mutation .

HY-143656

SH379	Autophagy	Endocrinology
SH379 is the derivative of 2-methylpyrimidine-fused tricyclic diterpene. SH379 is a potent and orally active anti-late-onset hypogonadism agent. SH379 significantly promotes the expression of the key testosterone synthesis-related enzymes StAR and 3β-HSD. SH379 stimulates autophagy through regulating AMPK/mTOR signaling pathway .

HY-155960

SH491	Others	Inflammation/Immunology
SH491 (Compound 33) is an antiosteoporosis agent. SH491 inhibits RANKL-induced osteoclast differentiation on bone-marrow-derived monocytes (BMMs) (IC₅₀: 11.8 nM). SH491 inhibits the expression of osteoclastogenesis-related marker genes (TRAP, CTSK, MMP-9, and ATPase v0d2) and proteins (TRAP, CTSK, MMP-9) .

HY-164526

SH1573	Isocitrate Dehydrogenase (IDH)	Cancer
SH1573 is an orally active mIDH2 inhibitor. SH1573 has a strong and selective inhibitory effect on mIDH2 R140Q protein (IC₅₀=4.78 nmol/L), and can effectively reduce the production of the carcinogenic metabolite 2-hydroxyglutarate (2-HG) in animal models, cell lines, serum and tumors. SH1573 can be used for the study of acute myeloid leukemia (AML) .

HY-159982

SH7s	Carbonic Anhydrase	Cancer
SH7s is a potent carbonic anhydrases inhibitor, with K_is of 15.9 and 55.2 nM for hCA IX and hCA XII, respectively. SH7s is also a hypoxia-mediated chemo-sensitizing agent in colorectal cancer cells .

HY-143658

SH498	BMI1 Autophagy	Cancer
SH498, a novel Bmi-1-mediated antitumor agent, shows potent antiproliferative activity.

HY-115857

SH-053-S-CH3-2'F	Others	Neurological Disease
SH-053-S-CH3-2'F is a selective positive allosteric modulator that produces mild to partial agonistic activity at α(1) GABA(A) receptors. SH-053-S-CH3-2'F showed anxiety-relieving effects at a dose of 30 mg/kg. SH-053-S-CH3-2'F completely avoids the memory impairment commonly caused by benzodiazepine site agonists. SH-053-S-CH3-2'F shows strong selectivity at GABA(A) receptors, which could potentially be used to develop more selective anti-anxiety drugs .

HY-139920

Oritinib SH-1028	EGFR	Cancer
Oritinib (SH-1028), an irreversible third-generation EGFR TKI, overcomes T790M-mediated resistance in non-small cell lung cancer. Oritinib (SH-1028), a mutant-selective inhibitor of EGFR kinase activity, inhibits EGFR ^WT, EGFR ^L858R, EGFR ^L861Q, EGFR ^L858R/T790M, EGFR ^d746-750 and EGFR ^{d746-750/T790M} kinases, with IC₅₀s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM, respectively .

HY-13558

Atamestane SH 489	Estrogen Receptor/ERR	Endocrinology
Atamestane (SH 489) is a specific aromatase inhibitor, which selectively blocks the estrogen biosynthesis resulting from the aromatization of androstenedione and testosterone. Atamestane is a competitive and irreversible inhibitor of estrogen biosynthesis. Atamestane can be used for the research of benign prostatic hyperplasia (BPH) .

HY-RS12826

SH3BGR Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3BGR Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BGR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3BGR Human Pre-designed siRNA Set A SH3BGR Human Pre-designed siRNA Set A

HY-RS12827

SH3BGRL Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3BGRL Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BGRL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3BGRL Human Pre-designed siRNA Set A SH3BGRL Human Pre-designed siRNA Set A

HY-161910

SH-E4A-66	Anaplastic lymphoma kinase (ALK)	Cancer
SH-E4A-66 is a C ²-COUPLr (COvalent Protein Ligator) with carbazole scaffold barring heterogeneous cysteine reactive warheads (acrylamide and chloroacetamide). SH-E4A-66 is capable of coupling with EML4-ALK (EC₅₀=1.5 μM) and inhibiting the activity of EML4-ALK kinase (IC₅₀=2.3 µM) .

HY-RS12818

SH2B1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH2B1 Human Pre-designed siRNA Set A contains three designed siRNAs for SH2B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH2B1 Human Pre-designed siRNA Set A SH2B1 Human Pre-designed siRNA Set A

HY-RS12819

SH2B2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH2B2 Human Pre-designed siRNA Set A contains three designed siRNAs for SH2B2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH2B2 Human Pre-designed siRNA Set A SH2B2 Human Pre-designed siRNA Set A

HY-RS12820

SH2B3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH2B3 Human Pre-designed siRNA Set A contains three designed siRNAs for SH2B3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH2B3 Human Pre-designed siRNA Set A SH2B3 Human Pre-designed siRNA Set A

HY-RS12828

SH3BGRL2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3BGRL2 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BGRL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3BGRL2 Human Pre-designed siRNA Set A SH3BGRL2 Human Pre-designed siRNA Set A

HY-RS12829

SH3BGRL3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3BGRL3 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BGRL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3BGRL3 Human Pre-designed siRNA Set A SH3BGRL3 Human Pre-designed siRNA Set A

HY-RS12830

SH3BP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3BP1 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3BP1 Human Pre-designed siRNA Set A SH3BP1 Human Pre-designed siRNA Set A

HY-RS12831

SH3BP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3BP2 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3BP2 Human Pre-designed siRNA Set A SH3BP2 Human Pre-designed siRNA Set A

HY-RS12832

SH3BP4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3BP4 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3BP4 Human Pre-designed siRNA Set A SH3BP4 Human Pre-designed siRNA Set A

HY-RS12833

SH3BP5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3BP5 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3BP5 Human Pre-designed siRNA Set A SH3BP5 Human Pre-designed siRNA Set A

HY-RS12834

SH3D19 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3D19 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3D19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3D19 Human Pre-designed siRNA Set A SH3D19 Human Pre-designed siRNA Set A

HY-RS12835

SH3D21 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3D21 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3D21 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3D21 Human Pre-designed siRNA Set A SH3D21 Human Pre-designed siRNA Set A

HY-RS12836

SH3GL1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3GL1 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3GL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3GL1 Human Pre-designed siRNA Set A SH3GL1 Human Pre-designed siRNA Set A

HY-RS12837

SH3GL2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3GL2 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3GL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3GL2 Human Pre-designed siRNA Set A SH3GL2 Human Pre-designed siRNA Set A

HY-RS12838

SH3GL3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3GL3 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3GL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3GL3 Human Pre-designed siRNA Set A SH3GL3 Human Pre-designed siRNA Set A

HY-RS12839

SH3GLB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3GLB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3GLB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3GLB1 Human Pre-designed siRNA Set A SH3GLB1 Human Pre-designed siRNA Set A

HY-RS12840

SH3GLB2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3GLB2 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3GLB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3GLB2 Human Pre-designed siRNA Set A SH3GLB2 Human Pre-designed siRNA Set A

HY-RS12841

SH3KBP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3KBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3KBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3KBP1 Human Pre-designed siRNA Set A SH3KBP1 Human Pre-designed siRNA Set A

HY-RS12844

SH3RF1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3RF1 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3RF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3RF1 Human Pre-designed siRNA Set A SH3RF1 Human Pre-designed siRNA Set A

HY-RS12845

SH3RF2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3RF2 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3RF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3RF2 Human Pre-designed siRNA Set A SH3RF2 Human Pre-designed siRNA Set A

HY-RS12846

SH3RF3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3RF3 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3RF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3RF3 Human Pre-designed siRNA Set A SH3RF3 Human Pre-designed siRNA Set A

HY-RS12847

SH3TC1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3TC1 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3TC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3TC1 Human Pre-designed siRNA Set A SH3TC1 Human Pre-designed siRNA Set A

HY-RS12848

SH3TC2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3TC2 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3TC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3TC2 Human Pre-designed siRNA Set A SH3TC2 Human Pre-designed siRNA Set A

HY-RS12849

SH3YL1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3YL1 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3YL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3YL1 Human Pre-designed siRNA Set A SH3YL1 Human Pre-designed siRNA Set A

HY-RS12821

SH2D1A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH2D1A Human Pre-designed siRNA Set A contains three designed siRNAs for SH2D1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH2D1A Human Pre-designed siRNA Set A SH2D1A Human Pre-designed siRNA Set A

HY-RS12823

SH2D2A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH2D2A Human Pre-designed siRNA Set A contains three designed siRNAs for SH2D2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH2D2A Human Pre-designed siRNA Set A SH2D2A Human Pre-designed siRNA Set A

HY-RS12825

SH2D4A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH2D4A Human Pre-designed siRNA Set A contains three designed siRNAs for SH2D4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH2D4A Human Pre-designed siRNA Set A SH2D4A Human Pre-designed siRNA Set A

HY-RS12842

SH3PXD2A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3PXD2A Human Pre-designed siRNA Set A contains three designed siRNAs for SH3PXD2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3PXD2A Human Pre-designed siRNA Set A SH3PXD2A Human Pre-designed siRNA Set A

HY-RS12822

SH2D1B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH2D1B Human Pre-designed siRNA Set A contains three designed siRNAs for SH2D1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH2D1B Human Pre-designed siRNA Set A SH2D1B Human Pre-designed siRNA Set A

HY-RS12824

SH2D3C Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH2D3C Human Pre-designed siRNA Set A contains three designed siRNAs for SH2D3C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH2D3C Human Pre-designed siRNA Set A SH2D3C Human Pre-designed siRNA Set A

HY-RS12843

SH3PXD2B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SH3PXD2B Human Pre-designed siRNA Set A contains three designed siRNAs for SH3PXD2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SH3PXD2B Human Pre-designed siRNA Set A SH3PXD2B Human Pre-designed siRNA Set A

HY-105825

Sermetacin SH-G 318AB	Endogenous Metabolite	Inflammation/Immunology
Sermetacin (SH-G 318AB) is an anti-inflammatory agent with biocompatibility and anti-inflammatory activity. Sermetacin is stable in saline and suitable for compound delivery. Sermetacin exhibits good biocompatibility in the RAW 264.7 mouse macrophage cell line. The anti-inflammatory response of sermetacin is comparable to that of its parent compound, indomethacin. Sermetacin may show potential in future applications of self-delivery of compound delivery .

HY-162355

SHP2-IN-27	SHP2	Cancer
SHP2-IN-27 (compound 28) is an allosteric inhibitor of tyrosine phosphatase *SH2* .

HY-113817

SHIP1 activator 1	Phosphatase	Inflammation/Immunology
SHIP1 activator 1 is an SH3 domain-containing inositol 5-phosphatase regulator with SHIP1 activating activity. SHIP1 activator 1 retains its SHIA-1 activating ability by removing unnecessary functional groups. SHIP1 activator 1 is able to activate SHIP1 in vitro, inhibit Akt phosphorylation in MOLT-4 cells, and show dose-dependent activity in a mouse model of inflammation. SHIP1 activator 1 is an important chemical tool for evaluating the potential of SHIP1 activators as inhibitors of hematopoietic diseases involving abnormal PI3K cell signaling .

Cat. No.	Product Name	Type

HY-D1543

Pyronin B	Fluorescent Dyes/Probes
Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor .

HY-D2381

AF 488 maleimide	Fluorescent Dyes/Probes
AF 488 maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach AF 488 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-D2246

ICG-SH	Fluorescent Dyes/Probes
ICG-SH?is a negatively charged polymethylcyanine dye.

HY-D0122

6-Iodoacetamidofluorescein	Fluorescent Dyes/Probes
6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins .

HY-D2306

DBCO-PEG-SH

Dyes

DBCO-PEG-SH is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D1869

800CW maleimide	Fluorescent Dyes/Probes
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .

Cat. No.	Product Name	Type

HY-W591476

m-PEG-thiol (MW 1000) mPEG-SH (MW 1000)	Drug Delivery
m-PEG-thiol (MW 1000) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.

HY-W591476B

m-PEG-thiol (MW 750) mPEG-SH (MW 750)	Drug Delivery
m-PEG-thiol (MW 750) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.

HY-W440896

DSPE-PEG-SH, MW 2000	Drug Delivery
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.

HY-W440897

DSPE-PEG-SH (MW 3400)	Drug Delivery
DSPE-PEG-SH, MW 3400 is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA. Reagent grade, for research use only.

HY-W440895

DSPE-PEG-SH (MW 1000)	Drug Delivery
DSPE-PEG-SH (MW 1000) is an amphiphilic poly-PEG that can form lipid bilayers in water. This amphiphilic polymer can form lipid bilayers in aqueous solution and can be used to embed active molecules for drug delivery systems such as mRNA vaccines.

HY-W591476A

m-PEG-thiol (MW 3400) mPEG-SH (MW 3400)	Drug Delivery
m-PEG-thiol (MW 3400) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.

HY-W591476C

m-PEG-thiol (MW 550) mPEG-SH (MW 550)	Drug Delivery
m-PEG-thiol (MW 550) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.

HY-W591476D

m-PEG-thiol (MW 350) mPEG-SH (MW 350)	Drug Delivery
m-PEG-thiol (MW 350) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.

HY-W440898

DSPE-PEG-SH (MW 5000)	Drug Delivery
DSPE-PEG-SH, MW 5000 is a polyPEG attached DSPE molecule. The lipid tails allow formation of lipid bilayer in water and can be used to solubilize hydrophobic drugs while the hydrophilic core can encapsulate therapeutic agents, such as nuclein acid (mRNA/DNA), protein or peptide. Reagent grade, for research use only.

HY-W698574

Dansylamidoethyl mercaptan	Indicators
Dansylamidoethyl mercaptan is a molecule that reacts with -SH groups of proteins and other sulfhydryl-containing molecules and has activity for detecting SS bonds in proteins.

Cat. No.	Product Name	Target	Research Area

HY-146127A

Grb2 SH2 domain inhibitor 1 TFA	Peptides	Others
Grb2 SH2 domain inhibitor 1 TFA is a conformationally restricted cyclic cell penetrating peptide (CPP) containing d-pro-l-pro motif ring (AF Φ Rpprrfq) (where Φ It is L-naphthylalanine, R is D-arginine, P is D-proline), which is mainly used as a cyclic peptide inhibitor.

HY-P3279

EPQpYEEIPIYL 1 Publications Verification	Src	Cancer
EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains .

HY-P5293

Acetyl sh-heptapeptide-1	Peptides	Others
Acetyl sh-heptapeptide-1 is a polypeptide. Acetyl sh-heptapeptide-1 is effective against facial aging .

HY-146127

Grb2 SH2 domain inhibitor 1	Peptides	Others
Grb2 SH2 domain inhibitor 1 is a conformationally restricted cyclic cell penetrating peptide (CPP) containing d-pro-l-pro motif ring (AF Φ Rpprrfq) (where Φ It is L-naphthylalanine, R is D-arginine, P is D-proline), which is mainly used as a cyclic peptide inhibitor.

HY-P5984

Thioether-cyclized helix B peptide, CHBP	mTOR	Others
Thioether-cyclized helix B peptide, CHBP can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2 .

HY-P5984A

Thioether-cyclized helix B peptide, CHBP TFA	mTOR	Others
Thioether-cyclized helix B peptide, CHBP (TFA) is the TFA form of Thioether-cyclized helix B peptide, CHBP (HY-P5984). Thioether-cyclized helix B peptide, CHBP (TFA) can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2 .

HY-P1200

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH	Src	Cancer
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC₅₀≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions .

HY-P1200A

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA	Src	Cancer
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC₅₀≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions .

HY-P3787

Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2	Peptides	Metabolic Disease
Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 is the SH2 domain ligand. SH2 domains participate in protein tyrosine kinase (PTK)-mediated cellular signal .

HY-P1377

Caffeic acid-pYEEIE	Src	Inflammation/Immunology
Caffeic acid-pYEEIE, a non-phosphopeptide inhibitor, exhibits potent binding affinity for the GST-Lck-SH2 domain .

HY-P1377A

Caffeic acid-pYEEIE TFA	Src	Inflammation/Immunology
Caffeic acid-pYEEIE TFA, a non-phosphopeptide inhibitor, exhibits potent binding affinity for the GST-Lck-SH2 domain .

HY-P10224

G7-18NATE	Peptides	Cancer
G7-18NATE is a peptide inhibitor of Grb7. HY-P10224 binds to the Grb7-SH2 domain with micromolar affinity (K_D = 18.1 μM). G7-18NATE inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines .

HY-P10224A

G7-18NATE TFA	Peptides	Cancer
G7-18NATE TFA is a peptide inhibitor of Grb7. G7-18NATE TFA binds to the Grb7-SH2 domain with micromolar affinity (K_d = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines .

HY-P10665

pYEEI	Src	Cancer
pYEEI is a phosphotyrosine-containing tetrapeptide binds to Src SH2 domain with the K_d of 100 nM and with the IC₅₀ of 6.5 μM. pYEEI plays an important role in cancer research .

HY-P5433

IRS1-derived peptide	Peptides	Others
IRS1-derived peptide is a biological active peptide. (This is a peptide fragment (979-989) of the insulin receptor substrate-1 containing the sequence motif YMXM known to bind to the two domains of SH2 on the 85kDa subunit of phosphoinositide 3-kinase.)

HY-P0175A

740 Y-P TFA 740YPDGFR TFA; PDGFR 740Y-P TFA	PI3K Autophagy	Cancer
740 Y-P TFA is a potent and cell-permeable PI3K activator. 740 Y-P TFA readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .

HY-P0175

740 Y-P Maximum Cited Publications 157 Publications Verification 740YPDGFR; PDGFR 740Y-P	PI3K Autophagy	Cancer
740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .

HY-P3275

β-Amyloid (17-40) Aβ(17-40)	Amyloid-β	Neurological Disease
β-Amyloid (17-40) (Aβ(17-40)) is a fragment of Amyloid-β peptide that has shown neurotoxic activities in SH-SY5Y and IMR-32 cells. β-Amyloid (17-40) can be used for the research of neurological disease .

HY-P5894

human GALP (3-32) Galanin-like peptide (3-32)	Neuropeptide Y Receptor	Neurological Disease
human GALP (3-32) (Galanin-like peptide (3-32)) is a potent galanin receptor agonist with high affinity for both GalR1 (IC₅₀=33 nM) and GalR2 (IC₅₀=15 nM) in a competitive binding study. human GALP (3-32) exhibits the high potency in altering the extracellular acidification rate of SH-SY5Y cells transfected with GalR2 (EC₅₀=360 nM) .

Species:	Human (19) Mouse (1)
Tag:	His (17) T7 (1) Tag Free (2) Strep (1) Myc (1) GST (2)
Source:	HEK293 (2) Sf9 insect cells (1) P. pastoris (1) E. coli (16)

Cat. No.	Compare	Product Name	Species	Source

HY-P71038

	SH2D1A Protein, Human (His) SH2 Domain-Containing Protein 1A; Duncan Disease SH2-Protein; Signaling Lymphocytic Activation Molecule-Associated Protein; SLAM-Associated Protein; T-Cell Signal Transduction Molecule SAP; SH2D1A; DSHP; SAP	Human	E. coli
	SH2D1A protein regulates receptors of the SLAM family (SLAMF1, CD244, LY9, CD84, SLAMF6, and SLAMF7). SH2D1A Protein, Human (His) is the recombinant human-derived SH2D1A protein, expressed by E. coli , with N-6*His labeled tag. The total length of SH2D1A Protein, Human (His) is 128 a.a., with molecular weight of ~16.0 kDa.

HY-P74549

	SHP-2 Protein, Mouse (HEK293, His) Tyrosine-protein phosphatase non-receptor type 11; SH-PTP2; SHP-2; Ptpn11	Mouse	HEK293
	SHP-2 Protein functions downstream of diverse receptor and cytoplasmic tyrosine kinases, participating in signal transduction from the cell surface to the nucleus.It positively regulates the MAPK pathway and dephosphorylates key proteins like GAB1, ARHGAP35, EGFR, ROCK2, CDC73, and SOX9.Additionally, SHP-2 dephosphorylates NEDD9/CAS-L to modulate cellular processes.SHP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SHP-2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700618

	SHP-2 Protein, Human (T253M, Q257L, His) protein tyrosine phosphatase, non-receptor type 11; Noonan syndrome 1 , NS1; tyrosine-protein phosphatase non-receptor type 11; BPTP3; PTP2C; SH PTP2; SHP 2; SHP2; PTP-2C; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; CFC; NS1; PTP-1D; SH-PTP2; SH-PTP3; MGC14433	Human	E. coli
	The SHP-2 protein is a key player downstream of the receptor and cytoplasmic protein tyrosine kinases, facilitating signal transduction from the cell surface to the nucleus. It actively regulates the MAPK pathway and dephosphorylates key substrates, including GAB1, ARHGAP35, EGFR, ROCK2 ("Tyr-722"), and CDC73. SHP-2 Protein, Human (T253M, Q257L, His) is the recombinant human-derived SHP-2 protein, expressed by E. coli , with N-6*His labeled tag and T253M, Q257L, , , mutation. The total length of SHP-2 Protein, Human (T253M, Q257L, His) is 592 a.a., with molecular weight of 70-75 kDa.

HY-P71141

	SHP-1 Protein, Human (His) Tyrosine-Protein Phosphatase Non-Receptor Type 6; Hematopoietic Cell Protein-Tyrosine Phosphatase; Protein-Tyrosine Phosphatase 1C; PTP-1C; Protein-Tyrosine Phosphatase SHP-1; SH-PTP1; PTPN6; HCP; PTP1C	Human	E. coli
	SHP-1 Protein modulates signaling from tyrosine-phosphorylated cell surface receptors, including KIT and EGFR. It enhances the inhibition of mast cell activation via the Lilrb4a receptor. The SH2 regions interact with cellular components to regulate its phosphatase activity. In collaboration with MTUS1, it induces UBE2V2 expression upon angiotensin II stimulation. SHP-1 plays a crucial role in hematopoiesis. SHP-1 Protein, Human (His) is the recombinant human-derived SHP-1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of SHP-1 Protein, Human (His) is 299 a.a., with molecular weight of ~33.0 kDa.

HY-P70396

	Grb2 Protein, Human (His) rHuGrowth factor receptor-bound protein 2/GRB2, His; Growth Factor Receptor-Bound Protein 2; Adapter Protein GRB2; Protein ASH; SH2/SH3 Adapter GRB2; GRB2; ASH	Human	E. coli
	Grb2, an adapter protein, crucially connects cell surface growth factor receptors to the Ras signaling pathway. Despite no direct binding to phosphorylated EGFR, Grb2 inhibits EGF-induced transactivation of a RAS-responsive element. It acts as a dominant negative relative to GRB2, suppressing proliferative signals and potentially initiating programmed cell death. Grb2 Protein, Human (His) is the recombinant human-derived Grb2 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P701568

	SH3RF3 Protein, Human SH3RF3; E3 ubiquitin-protein ligase SH3RF3; Plenty of SH3s 2; SH3 domain-containing RING finger protein 3; SH3 multiple domains protein 4	Human	E. coli
	SH3RF3 protein is an E3 ubiquitin protein ligase that plays a key role in mediating the transfer of ubiquitin to target proteins, affecting protein degradation, cell signaling, and various biological processes. As an E3 ligase, SH3RF3 may promote ubiquitin-mediated proteasomal degradation of specific substrate proteins, thereby affecting their cellular levels and activity. SH3RF3 Protein, Human is the recombinant human-derived SH3RF3 protein, expressed by E. coli , with tag free. The total length of SH3RF3 Protein, Human is 881 a.a., .

HY-P701569

	SH3RF3 Protein, Human (His) SH3RF3; E3 ubiquitin-protein ligase SH3RF3; Plenty of SH3s 2; SH3 domain-containing RING finger protein 3; SH3 multiple domains protein 4	Human	E. coli
	SH3RF3 protein is an E3 ubiquitin protein ligase that plays a key role in mediating the transfer of ubiquitin to target proteins, affecting protein degradation, cell signaling, and various biological processes. As an E3 ligase, SH3RF3 may promote ubiquitin-mediated proteasomal degradation of specific substrate proteins, thereby affecting their cellular levels and activity. SH3RF3 Protein, Human (His) is the recombinant human-derived SH3RF3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SH3RF3 Protein, Human (His) is 881 a.a., .

HY-P71572

	SH3PXD2A Protein, Human (Myc, His) Adapter protein TKS5; Five SH3 domain-containing protein; SH3 and PX domain-containing protein 2A; SH3 multiple domains protein 1; SH3md1; SH3pxd2a; SPD2A_HUMAN; TKs5; Tyrosine kinase substrate with five SH3 domains	Human	E. coli
	SH3PXD2A is an adapter protein that plays a crucial role in the formation of invadopodia and podosomes, thereby enhancing the invasiveness of cancer cells. It interacts with ADAM, NOX and phosphoinositides and contributes to a variety of cellular processes. SH3PXD2A Protein, Human (Myc, His) is the recombinant human-derived SH3PXD2A protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of SH3PXD2A Protein, Human (Myc, His) is 85 a.a., with molecular weight of ~14.0 kDa.

HY-P703318

	DBNL Protein, Human (HEK293, His, Strep) CMAP; SH3P7	Human	HEK293
	DBNL Protein, Human (HEK293, His, Strep) is the recombinant human-derived DBNL, expressed by HEK293 , with Strep, His labeled tag. The total length of DBNL Protein, Human (HEK293, His, Strep) is 430 a.a.,

HY-P70304

	NCK1 Protein, Human (His) rHuCytoplasmic protein NCK1/NCK1, His; Cytoplasmic Protein NCK1; NCK adaptor Protein 1; Nck-1; SH2/SH3 Adaptor Protein NCK-Alpha; NCK1; NCK	Human	E. coli
	NCK1 protein is an adapter protein that binds to tyrosine phosphorylated receptors (KDR, PDGFRB) and cellular substrates and plays a key role in the dephosphorylation of EIF2S1 by PP1. It contributes to the efficient activation of DNA damage response effector (CHEK2) and ELK1-dependent transcriptional activation in Ras signaling. NCK1 Protein, Human (His) is the recombinant human-derived NCK1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P77099

	NCKIPSD Protein, Human (His) NCK-interacting protein with SH3 domain; VIP54; WISH; AF3P21; SPIN90	Human	E. coli
	NCKIPSD Protein, vital for stress fiber formation induced by active DRF1, stimulates N-WASP-induced ARP2/3 complex activation, independent of CDC42. Implicated in sarcomere maintenance, myofibril assembly, actin polymerization, and angiogenesis. Associates with vimentin, desmin, NCK, GRB2, and interacts with Helicobacter pylori toxin vacA, FHOD1, FASLG, and TMIGD2, showcasing its diverse cellular interactions. NCKIPSD Protein, Human (His) is the recombinant human-derived NCKIPSD protein, expressed by E. coli, with N-His labeled tag. The total length of NCKIPSD Protein, Human (His) is 244 a.a., with molecular weight of ~33-45 kDa.

HY-P701458

	AMSH Protein, Human STAMBP; STAM-binding protein; Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase	Human	E. coli
	AMSH is a zinc metalloprotease that selectively cleaves "Lys-63"-linked polyubiquitin chains, but not "Lys-48"-linked chains. It plays a critical regulatory role in signaling in IL-2 and GM-CSF mediated pathways, acting as a positive BMP signaling modulator against SMAD6 and SMAD7 inhibition. AMSH Protein, Human is the recombinant human-derived AMSH protein, expressed by E. coli , with tag free. The total length of AMSH Protein, Human is 423 a.a., .

HY-P76687

	UBASH3A Protein, Human (His) Ubiquitin-associated and SH3 domain-containing protein A; CLIP4; STS-2; TULA-1	Human	E. coli
	UBASH3A interferes with CBL-mediated downregulation and degradation of receptor-type tyrosine kinases and promotes the accumulation of activating receptors such as T cell receptors, EGFR and PDGFRB on the cell surface. It exhibits minimal protein tyrosine phosphatase activity and may act as a dominant negative regulator of UBASH3B-dependent dephosphorylation. UBASH3A Protein, Human (His) is the recombinant human-derived UBASH3A protein, expressed by E. coli , with N-His labeled tag.

HY-P701459

	AMSHLP Protein, Human (His) STAMBP; STAM-binding protein; Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase	Human	E. coli
	AMSHLP is a zinc metalloprotease that selectively cleaves "Lys-63" linked polyubiquitin chains and acts as a positive regulator of the TORC1 signaling pathway. It specifically deubiquitinates SESN2, disrupts its interaction with the GATOR2 complex and inhibits SESN2-mediated regulation of TORC1. AMSHLP Protein, Human (His) is the recombinant human-derived AMSHLP protein, expressed by E. coli , with N-6*His labeled tag. The total length of AMSHLP Protein, Human (His) is 435 a.a., .

HY-P74484

	UBASH3B/STS1 Protein, Human (His) Ubiquitin-associated and SH3 domain-containing protein B; STS-1; TULA-2; UBASH3B	Human	E. coli
	UBASH3B/STS1 protein blocks CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases, leading to the accumulation of activating receptors such as T cell receptors and EGFR on the cell surface. It exhibits tyrosine phosphatase activity against substrates such as EGFR, FAK, SYK and ZAP70. UBASH3B/STS1 Protein, Human (His) is the recombinant human-derived UBASH3B/STS1 protein, expressed by E. coli , with N-His, N-6*His labeled tag. The total length of UBASH3B/STS1 Protein, Human (His) is 268 a.a., with molecular weight of ~30 kDa.

HY-P702856

	G3BP1 Protein, Human (His) G3BP-1; ATP-dependent DNA helicase VIII; hDH VIII; GAP SH3 domain-binding protein 1	Human	E. coli
	G3BP1 Protein, Human (His) is the recombinant human-derived G3BP1, expressed by E. coli , with N-6*His labeled tag. The total length of G3BP1 Protein, Human (His) is 466 a.a.,

HY-P71320

	SLP-76 Protein, Human (His-T7) Lymphocyte cytosolic protein 2; SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein; SLP76; LCP2	Human	E. coli
	The SLP-76 protein is critical in T cell antigen receptor-mediated signaling and participates in multiple molecular interactions. Its association with SLA coordinates T cell signaling, whereas its interaction with CBLB emphasizes regulatory effects. SLP-76 Protein, Human (His-T7) is the recombinant human-derived SLP-76 protein, expressed by E. coli , with N-T7, C-6*His labeled tag. The total length of SLP-76 Protein, Human (His-T7) is 533 a.a., with molecular weight of ~70.0 kDa.

HY-P701776

	SBK3 Protein, Human (Sf9, His, GST) SBK3; Uncharacterized serine/threonine-protein kinase SBK3; SH3-binding domain kinase family member 3; Sugen kinase 110	Human	Sf9 insect cells
	SBK3 Protein, Human (Sf9, His, GST) is the recombinant human-derived SBK3 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of SBK3 Protein, Human (Sf9, His, GST) is 358 a.a., .

HY-P71785

	SOCS1 Protein, Human (P.pastoris, His) CISH 1; CISH1; Cytokine inducible SH2 protein 1; JAB; JAK binding protein; JAK-binding protein; Janus kinase binding protein ; SOCS 1; TEC interacting protein 3; Tec-interacting protein 3; TIP 3	Human	P. pastoris
	The SOCS1 protein is an important negative regulator that inhibits type I and type II interferon signaling as well as cytokines such as IL2, IL4, IL6, and LIF. It downregulates the signaling of the JAK/STAT pathway by inhibiting JAK proteins and IFNGR1. SOCS1 Protein, Human (P.pastoris, His) is the recombinant human-derived SOCS1 protein, expressed by P. pastoris , with N-His labeled tag. The total length of SOCS1 Protein, Human (P.pastoris, His) is 211 a.a., with molecular weight of ~25.6 kDa.

HY-P70290

	Neutrophil cytosol factor 1 Protein, Human (His) rHuNeutrophil cytosol factor 1/NCF1, His; NCF-1; 47 kDa autosomal chronic granulomatous disease protein/47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2/SH3 and PX domain-containing protein 1A; p47-phox	Human	E. coli
	Neutrophil cytoplasmic factor 1 (NCF1) is essential for activation of the NADPH oxidase complex, which is essential for superoxide production. It cooperates with NCF2 to form a core association in the complex, interacting with NCF4, CYBB and CYBA. Neutrophil cytosol factor 1 Protein, Human (His) is the recombinant human-derived Neutrophil cytosol factor 1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of Neutrophil cytosol factor 1 Protein, Human (His) is 390 a.a., with molecular weight of 45-50 kDa.

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82205

	SH2D1A Antibody (YA1950) LYP; SAP; XLP; DSHP; EBVS; IMD5; XLPD; MTCP1; XLPD1; SAP/SH2D1A	WB	Human, Mouse, Rat
	SH2D1A Antibody (YA1950) is a biotin-conjugated non-conjugated IgG antibody, targeting SH2D1A, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). SH2D1A Antibody (YA1950) can be used for WB experiment in human, mouse, rat background.

HY-P81898

	SHP2 Antibody (YA1643) PTPN11; PTP2C; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; SHp2; SH-PTP3	WB, IHC-P, IP	Human
	SHP2 Antibody (YA1643) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1643), targeting SHP2, with a predicted molecular weight of 68 kDa (observed band size: 68 kDa). SHP2 Antibody (YA1643) can be used for WB, IHC-P, IP experiment in human background.

HY-P83087

	SHIP1 Antibody (YA2832) INPP5D; SHIP; SHIP1; Phosphatidylinositol 3; 4; 5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1	WB, IHC-P, IP, FC	Human
	SHIP1 Antibody (YA2832) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2832), targeting SHIP1, with a predicted molecular weight of 133 kDa (observed band size: 140 kDa). SHIP1 Antibody (YA2832) can be used for WB, IHC-P, IP, FC experiment in human background.

HY-P81307

	SHP1 Antibody (YA1044) PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IP	Human
	SHP1 Antibody (YA1044) is a mouse-derived non-conjugated IgG2a antibody (Clone NO.: YA1044), targeting SHP1, with a predicted molecular weight of 68 kDa (observed band size: 68 kDa). SHP1 Antibody (YA1044) can be used for WB, IP experiment in human background.

HY-P81307A

	SHP1 Antibody (YA1045) PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IHC-P	Human
	SHP1 Antibody (YA1045) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1045), targeting SHP1, with a predicted molecular weight of 68 kDa (observed band size: 68 kDa). SHP1 Antibody (YA1045) can be used for WB, IHC-P experiment in human background.

HY-P82649

	SHC Antibody (YA2394) SHC1; SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	SHC Antibody (YA2394) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2394), targeting SHC, with a predicted molecular weight of 63 kDa (observed band size: 46, 52, 66 kDa). SHC Antibody (YA2394) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

HY-P82208

	SNX9 Antibody (YA1953) SDP1; WISP; SH3PX1; SH3PXD3A	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse
	SNX9 Antibody (YA1953) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1953), targeting SNX9, with a predicted molecular weight of 67 kDa (observed band size: 67 kDa). SNX9 Antibody (YA1953) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.

HY-P80695

	GRB2 Antibody (YA748) GRB2; ASH; Growth factor receptor-bound protein 2; Adapter protein GRB2; Protein ASH; SH2/SH3 adapter GRB2	WB	Human, Mouse, Rat
	GRB2 Antibody (YA748) is a non-conjugated and Mouse origined monoclonal antibody about 25 kDa, targeting to GRB2 (5G3). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P83394

	NCF4 Antibody (YA3139) NCF; CGD3; P40PHOX; SH3PXD4	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	NCF4 Antibody (YA3139) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3139), targeting NCF4, with a predicted molecular weight of 39 kDa (observed band size: 39 kDa). NCF4 Antibody (YA3139) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

HY-P83548

	NCK2 Antibody (YA3293) NCK2; GRB4; Cytoplasmic protein NCK2; Growth factor receptor-bound protein 4; NCK adaptor protein 2; Nck-2; SH2/SH3 adaptor protein NCK-beta	WB, ICC/IF	Human, Mouse, Rat
	NCK2 Antibody (YA3293) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3293), targeting NCK2, with a predicted molecular weight of 43 kDa (observed band size: 43 kDa). NCK2 Antibody (YA3293) can be used for WB, ICC/IF experiment in human, mouse, rat background.

HY-P82830

	NCF1 Antibody (YA2575) NCF1; NCF1A; NOXO2; SH3PXD1A; p47phox	WB, IP	Human
	NCF1 Antibody (YA2575) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2575), targeting NCF1, with a predicted molecular weight of 45 kDa (observed band size: 45 kDa). NCF1 Antibody (YA2575) can be used for WB, IP experiment in human background.

HY-P83344

	Phospho-SHIP1 (Tyr1020) Antibody (YA3089) INPP5D; SHIP; SHIP1; Phosphatidylinositol 3; 4; 5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1	WB, ICC/IF, IP	Human
	Phospho-SHIP1 (Tyr1020) Antibody (YA3089) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3089), targeting Phospho-SHIP1 (Tyr1020), with a predicted molecular weight of 133 kDa (observed band size: 145 kDa). Phospho-SHIP1 (Tyr1020) Antibody (YA3089) can be used for WB, ICC/IF, IP experiment in human background.

HY-P82687

	G3BP Antibody (YA2432) G3BP1; G3BP; Ras GTPase-activating protein-binding protein 1; G3BP-1; ATP-dependent DNA helicase VIII; hDH VIII; GAP SH3 domain-binding protein 1	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	G3BP Antibody (YA2432) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2432), targeting G3BP, with a predicted molecular weight of 52 kDa (observed band size: 68 kDa). G3BP Antibody (YA2432) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P82537

	BLNK Antibody (YA2282) BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa	WB, IP	Human, Mouse, Rat
	BLNK Antibody (YA2282) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2282), targeting BLNK, with a predicted molecular weight of 50 kDa (observed band size: 70 kDa). BLNK Antibody (YA2282) can be used for WB, IP experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-130900

Propargyl-PEG3-SH		PROTAC Synthesis Alkynes
Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135917

Propargyl-PEG6-SH		Alkynes PROTAC Synthesis
Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130910

Propargyl-PEG8-SH		PROTAC Synthesis Alkynes
Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG8-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130911

Propargyl-PEG12-SH		PROTAC Synthesis Alkynes
Propargyl-PEG12-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG12-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.