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Results for "

Antiviral Agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (55) Apoptosis (27) Arenavirus (2) ATP Synthase (1) Autophagy (6) Bacterial (27) Bcl-2 Family (6) Biochemical Assay Reagents (2) Btk (1) Calcium Channel (1) CDK (7) CMV (14) Cytochrome P450 (3) Dengue virus (9) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (15) Drug Metabolite (1) E1/E2/E3 Enzyme (2) EBV (3) Endogenous Metabolite (9) Enterovirus (9) Filovirus (4) Flavivirus (14) Fungal (13) Glucosidase (4) HBV (19) HCV (13) HCV Protease (3) HDAC (1) HIV (25) HIV Integrase (1) HPV (3) HSP (2) HSV (41) Influenza Virus (43) Isotope-Labeled Compounds (13) Mitophagy (2) MMP (2) NF-κB (4) NO Synthase (1) Nucleoside Antimetabolite/Analog (18) Opioid Receptor (1) Orthopoxvirus (22) Parasite (4) Phosphatase (3) PI4K (1) PKC (1) PROTAC Linkers (3) Reactive Oxygen Species (2) Reverse Transcriptase (6) RSV (8) SARS-CoV (40) Tau Protein (1) Thymidylate Synthase (3) TMV (5) Topoisomerase (1) Virus Protease (13)
By Research Areas:	Cancer (68) Cardiovascular Disease (3) Infection (263) Inflammation/Immunology (29) Metabolic Disease (9) Neurological Disease (12)
Click Chemistry:	Azide (2)
Oligonucleotides:	Nucleosides and their Analogs (4) Nucleoside Phosphoramidites (2) Antisense Oligonucleotides (1)

281

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-146344

Antiviral agent 17	Antibiotic	Infection
Antiviral agent 17 (Compound 4) is an anti-infection agent. Antiviral agent 17 retains its antiviral effect in a human replicon assay (EC₅₀ = 0.015 μM). Antiviral agent 17 results in good antiviral activity against murine norovirus. Antiviral agent 17 has the potential for the research of infectious and malignant diseases .

HY-153758

Antiviral agent 30	HCV RSV	Infection
Antiviral agent 30 (Example 118) is an antiviral agent. Antiviral agent 30 is active against HCV and RSV (IC₅₀: > 25μM) .

HY-164139

Antiviral agent 57	Others	Infection
Antiviral agent 57 (compound 81) is an antiviral agent.Antiviral agent 57 shows > 60% inhibition aganist ANO6 at the 50 nM .

HY-157454

Antiviral agent 48	Others	Infection
Antiviral agent 48 (compound 9m) is a pan-antiviral agent. Antiviral agent 48 has anti-HEV activity and cytotoxicity (EC₉₀=30.6 nM; CC₅₀=13.8 nM) .

HY-161047

Antiviral agent 45	HIV	Infection
Antiviral agent 45 (compound 9a) is an antiviral agent. Antiviral agent 45 inhibits HIV-1 andHIV-2 with IC₅₀s of 35 and 3.1 nM, respectively .

HY-157291

Antiviral agent 44	Antibiotic HCV	Infection
Antiviral agent 44 (compound 7b) is an antiviral agent that has *anti-HCV* activity in vitro .

HY-N12691

Antiviral agent 51	Dengue virus	Infection
Antiviral agent 51 (compound a) is a potent antiviral agent. Antiviral agent 51 is a fucoidan. Antiviral agent 51 interacts with DENV-2 RNA Dependant RNA polymerase (RdRp) .

HY-161454

Antiviral agent 54	Virus Protease Influenza Virus SARS-CoV	Infection
Antiviral agent 54 (compound 33) is a broad-spectrum and orally active antiviral agent. Antiviral agent 54 shows antiviral activity for ZIKV, HCoV-OC43 and influenza A virus (IVA). Antiviral agent 54 decreases the ZIKV RNA and protein level .

HY-146345

Antiviral agent 18	Antibiotic	Infection
Antiviral agent 18 (Compound 5) is an anti-infection agent. Antiviral agent 18 results in good antiviral activity against murine norovirus. Antiviral agent 18 has the potential for the research of infectious and malignant diseases .

HY-149468

Antiviral agent 38	HBV	Infection
Antiviral agent 38 (compound 2.1-1) is a potent antiviral agent. Antiviral agent 38 can be used for hepatitis B virus (HBV) research .

HY-161264

Antiviral agent 49	Bacterial	Infection
Antiviral agent 49 (compound 4q) is dual antiviral and antibacterial agent. Antiviral agent 49 shows anti-enterococcus activity and anti-staphylococcal activity .

HY-115848

Antiviral agent 12	Filovirus	Infection
Antiviral agent 12 is a antiviral compound. Antiviral agent 12 inhibits Ebola virus entry into host cells by binding to surface glycoprotein, EC₅₀ is 3.9 μM. Antiviral agent 12 can be used in the study of Ebola virus .

HY-151924

Antiviral agent 23	Enterovirus	Infection
Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC₅₀ value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection .

HY-164122

Antiviral agent 56	HIV	Infection
Antiviral agent 56 (Compound 4) is an antiviral agent that has anti-HIV activity .

HY-142009

Antiviral agent 10	RSV	Infection
Antiviral agent 10 is an anti-viral agent that can inhibit respiratory syncytial virus (RSV) .

HY-N12362

Antiviral agent 41	Influenza Virus	Infection
Antiviral agent 41 (compound 5) is a diarylheptanoid isolated from Alpinia officinarum. Antiviral agent 41 exhibits potential antiviral activity against influenza virus in vitro .

HY-155110

Antiviral agent 34	Influenza Virus	Infection
Antiviral agent 34 is a potent and orally active antiviral agent against influenza A and B subtypes with an EC₅₀ value of 0.8 nM for H1N1 proliferation. Antiviral agent 34 derivatives inhibited influenza virus proliferation by targeting influenza virus RNA-dependent RNA polymerase. Antiviral agent 34 can be used for influenza virus research .

HY-145324

Antiviral agent 14	TMV	Infection
Antiviral agent 14 is an antiviral agent against the tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). The EC50 values of Antiviral agent 14 against TMV and CMV with EC₅₀ values of 135.5 μg/mL and 178.6 μg/mL, respectively .

HY-139683

Antiviral agent 5	SARS-CoV	Infection
Antiviral agent 5 is an intermediate used in antiviral agents targeting 3C and 3CL proteases including SARS-CoV-2 M ^pro.

HY-169281

Antiviral agent 61	Others	Infection
Antiviral agent 61 (compound Z40) is a potent antiviral agent. Antiviral agent 61 shows anti tomato spotted wilt virus (TSWV) activity with an EC₅₀ value of 252 µg/mL. Antiviral agent 61 increases the RNA expression of Ndufb9, COX6B, 7.1.2.2, E, COX5B, Ndufs4, and SDHB, decreases the RNA expression of Ndufb7, Ndufa5, and G .

HY-151926

Antiviral agent 24	Enterovirus	Infection
Antiviral agent 24 is a potent *antiviral* agent with EC₅₀ values of 0.101, 19.9, 91.2 µM for EV71, CVA21, EV68, respectively. Antiviral agent 24 inhibits METTL3/METTL14 activity in a dose-dependent manner .

HY-161956

Antiviral agent 59	Filovirus	Infection
Antiviral agent 59 (compound 58) is an *antiviral* agent with selective and drug-like properties that inhibits a broad spectrum of filoviruses. Antiviral agent 59 exhibits low off-target activity and inhibition against replication-competent Ebola virus (EBOV), Sudan virus (SUDV), and Marburg virus (MARV/b>) .

HY-169291

Antiviral agent 62	HIV	Infection
Antiviral agent 62 (Compound 16 h) is an orally active antiviral agent that inhibits the activity of HIV with an IC₅₀ value of 8 nM against HIV (MJ4) .

HY-146417

Antiviral agent 19	Flavivirus	Infection
Antiviral agent 19 (Compound 3) is a selective inhibitor against Zika virus infection with an EC₅₀ of 1.3 µM. Antiviral agent 19 has low cytotoxicity .

HY-162069

Antiviral agent 47	HSV	Infection
Antiviral agent 47 (Compound 26) is an antiviral agent, which inhibits HSV-1 with ID₅₀ of 16 μM, through suppression of herpes virus replication .

HY-139817

Antiviral agent 8	Antibiotic	Infection
Antiviral agent 8 with significantly higher antiviral activities than lead compounds (crocin-1 and crocin-2) emerges as a new antiviral candidate.

HY-144623

Antiviral agent 15	SARS-CoV	Infection
Antiviral agent 15 (Compound 15f) is a Clofazimine derivative with antiviral effects. Antiviral agent 15 inhibits both rabies virus and pseudo-typed SARS-CoV-2 with EC₅₀ values of 1.45 μM and 14.6 μM, respectively .

HY-146418

Antiviral agent 20	Flavivirus	Infection
Antiviral agent 20 (Compound 17b) is a selective inhibitor against Zika virus infection with an EC₅₀ of 4.5 µM. Antiviral agent 20 has low cytotoxicity .

HY-162403

Antiviral agent 53	Others	Infection
Antiviral agent 53 (Compound (S)-4v) is an antiviral agent that can inhibit the activity of Potato virus Y (PVY) and exhibit excellent curative and protective effects against PVY with EC₅₀ values of 328.6 and 256.1 μg/mL, respectively. Antiviral agent 53 can be used in the research and development of novel pesticides .

HY-147700

Antiviral agent 21	Enterovirus	Infection
Antiviral agent 21 (Compound 4) is an anti-EV71 agent .

HY-113860

Antiviral agent 52	HCV	Infection
Antiviral agent 52 (Compound 30) is a Chlorcyclizine (HY-112067) derivative that exhibits antiviral activity against hepatitic C virus (HCV) with an EC₅₀ of 17 nM. Antiviral agent 52 reveals cytotoxicity in cell Huh7.5.1 with CC₅₀ of 21.3 μM .

HY-158258

Antiviral agent 55	HIV	Infection
Antiviral agent 55 (Compound 95) is an inhibitor for human immunodeficiency virus 1 and 2 (HIV 1 and HIV 2), and exhibits antiviral activity .

HY-152589

Antiviral agent 25	SARS-CoV	Infection
Antiviral agent 25 (compound 6g) is a new non-peptide analog covalent inhibitor of SARS-CoV-2 3CL ^pro. Antiviral agent 25 has a strong inhibitory effect on SARS-CoV-2 3CL ^pro and SARS-CoV-2 PL ^pro with IC₅₀ values of 0.118 µM, 0.448 µM, respectively. Antiviral agent 25 has antiviral effect on SARS-CoV-2 with an EC₅₀ value of 7.249 µM .

HY-132916

Antiviral agent 7	Others	Infection
Antiviral agent 7 is a peptide-based coating that can kill viruses.

HY-149900

Antiviral agent 33	Biochemical Assay Reagents	Infection
Antiviral agent 33 (compound 1c) is a double-stranded DNA (dsDNA) virus inhibitor with IC₅₀ values of 0.0790 and 0.1572 µM for VACV and AdV5, respectively. Antiviral agent 33 also has potential for oral administration .

HY-162701

Antiviral agent 58	SARS-CoV Influenza Virus RSV HSV	Infection
Antiviral agent 58 (Compound J1) is an orally active antiviral agent with broad-spectrum antiviral activity against enveloped viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human coronavirus OC43 (HCoV-OC43), herpes simplex virus type 1 (HSV-1), and HSV-2 .

HY-132911

Antiviral agent 6	Others	Infection
Antiviral agent 6 shows excellent anti-TSWV activity in vivo, and the EC₅₀ value is 188 mg/L.

HY-155129

Antiviral agent 36	DNA/RNA Synthesis	Infection
Antiviral agent 36 (compound 27) is a potent dengue (DENV) and Zika (ZIKV) viruses inhibitor. Antiviral agent 36 inhibits replication of Zika and dengue virus with EC₅₀s of 100 nM, 90 nM, 210 nM, and 120 nM for ZIKV-FLR, ZIKV-HN16, DENV-2, and DENV-3, respectively .

HY-149217

Antiviral agent 27	Others	Infection
Antiviral agent 27 (Compound 12) has notable activity against the Ebola virus (EC₅₀: 14 nM) .

HY-155731

Antiviral agent 35	Influenza Virus	Infection
Antiviral agent 35 (compound 4d) is an orally active and potent influenza virus inhibitor, acting function in the early stage of virus replication. Antiviral agent 35 inhibits ROS accumulation, autophagy and apoptosis induced by influenza virus, and also inhibits inflammatory response mediated by RIG-1 pathway in mouse model with pulmonary infection. Antiviral agent 35 shows little cytotoxicity with CC₅₀ >800 μM in MDCK cells, and anti-H1N1 (A/Weiss/43) activity with EC₅₀ of 2.28 μM .

HY-157249

Antiviral agent 43	Influenza Virus	Infection
Antiviral agent 43 (compound 16) is a potent and orally active influenza A viruses entry inhibitor. Antiviral agent 43 inhibits replications of influenza A strains VH04-H5N1 and PR8-H1N1 with EC₅₀s of 240 nM and 72 nM, respectively .

HY-161070

Antiviral agent 46	SARS-CoV Angiotensin-converting Enzyme (ACE)	Infection
Antiviral agent 46 (compound 4) is a derivative of cannabidiol (CBD) with anti-SARS-CoV-2 (IC₅₀: 1.90 μM) and ACE2 activity (IC₅₀: 1.37 μM) .

HY-139845

Antiviral agent 9	HIV	Infection
Antiviral agent 9 reaches a single-digit picomolar EC₅₀ value (0.006 nM) against HIV-1 and nearly 300-fold higher selectivity index (SI) compared to tenofovir alafenamide fumarate (TAF).

HY-W269306

Bonaphthone	DNA/RNA Synthesis Influenza Virus	Infection
Bonaphthone is an antiviral agent with anti-DNA and -RNA viral activities .

HY-122356A

Ambazone	Bacterial	Cancer
Ambazone is an orally active membrane active antitumor agent. Ambazone also shows antibacterial and weak antiviral activities .

HY-122356

Ambazone monohydrate	Bacterial	Cancer
Ambazone monohydrate is an orally active membrane active antitumor agent. Ambazone monohydrate also shows antibacterial and weak antiviral activities .

HY-155045

TMV-IN-6	TMV	Infection
TMV-IN-6 (Compound 4g) is a novel antiviral and fungicidal agent. TMV-IN-6 inhibits virus assembly by binding totobacco mosaic virus (TMV) CP and interfere with the assembly process of TMV CP and RNA .

HY-150581

CYP3A4-IN-3	Cytochrome P450	Infection Inflammation/Immunology
CYP3A4-IN-3 is a high-affinity specific inhibitor of cytochrome P450 3A4 (CYP3A4) with the IC₅₀ value of 0.075 μM. CYP3A4-IN-3 is a ritonavir analogue, but with a simpler structure and twice the inhibitory effect of ritonavir. CYP3A4-IN-3 is used as an antiviral agent and immunosuppressant .

HY-163754

TMV-IN-9	TMV	Infection
TMV-IN-9 (compound A6) is an antiviral agent that displays excellent inactivating against tobacco mosaic virus (TMV) with an EC₅₀ of 62.8 μg/mL. TMV-IN-9 shows strong binding capacity to TMV coat protein with a binding affinity value of 1.862 μM. TMV-IN-9 obviously destroys the integrity of the TMV particles and blocked the virus from infecting the host .

HY-150580

CYP3A4-IN-2	Cytochrome P450	Inflammation/Immunology Cancer
CYP3A4-IN-2 is a specific inhibitor of cytochrome P450 3A4 (CYP3A4) with the IC₅₀ value of 0.055 μM. CYP3A4-IN-2 is a ritonavir analogue with increased hydrophobicity of the R2 side group and stronger inhibitory effect compared to ritonavir. CYP3A4-IN-2 can be used as an antiviral agent and immunosuppressants .

Cat. No.	Product Name

HY-L002

Anti-Infection Compound Library

3,074 compounds

An infection occurs when another organism enters a person’s body and causes disease. The organisms that cause infections are very diverse and can include things like viruses, bacteria, fungi, and parasites. The immune system is an effective barrier against infectious agents.

MCE provides a unique collection of 3,074 anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities that can be used for drug screening and other research in anti-microbial area.

HY-L073

Anti-Hepatitis C Virus Compound Library

295 compounds

Hepatitis C virus (HCV) is a hepatotropic enveloped positive- strand RNA virus (family Flaviviridae) that infects the parenchymal cells of the liver. HCV infection is a significant public health burden. Globally, an estimated 71 million people have chronic hepatitis C virus infection. A significant number of those who are chronically infected will develop cirrhosis or liver cancer. To date, there is no vaccine against HCV, and combination pegylated alpha interferon (pIFN-) and ribavirin, the main standard-of-care treatment for HCV, is effective in only a subset of patients and is associated with a wide spectrum of toxic side effects and complications. More recently, new therapeutic approaches that target essential components of the HCV life cycle have been developed, including direct-acting antiviral (DAA) that specifically block a viral enzyme or functional protein and host-targeted agents (HTA) that block interactions between host proteins and viral components that are essential to the viral life cycle. However, the genetic diversity of HCV viruses and the stage of liver disease (i.e., cirrhosis) are revealing themselves as obstacles for effective, pan-genotypic treatments. There still exists a need for the discovery and development of new HCV inhibitors. In particular, since the future of HCV therapy will likely consist of a cocktail approach using multiple inhibitors that target different steps of infection, new antivirals targeting all steps of the viral infection cycle.

MCE offers a unique collection of 295 compounds with identified and potential anti-HCV activity. MCE Anti- Hepatitis C Virus Compound Library is a useful tool for discovery new anti-HCV drugs and other anti-infection research.

Cat. No.	Product Name	Type

HY-128382

Brilliant Black BN E 151	Dyes
Brilliant black BN (E151) is an azo dye and a food colorant . Brilliant black BN is a promising **antiviral agent against EV71** infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. Brilliant black BN has the potential for the investigation of contagious disease .

HY-D0214

Rose Bengal sodium 1 Publications Verification	Fluorescent Dyes/Probes
Rose Bengal sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities .

HY-B0434G

Ribavirin (GMP) Ribasphere (GMP); ICN-1229 (GMP)	Fluorescent Dye
Ribavirin (GMP) is Ribavirin (HY-B0434) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.

HY-D0214R

Rose Bengal sodium (Standard)

Fluorescent Dyes/Probes

Rose Bengal (sodium) (Standard) is the analytical standard of Rose Bengal (sodium). This product is intended for research and analytical applications. Rose Bengal sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities .

Cat. No.	Product Name	Type

HY-41343

Triacetyl-ganciclovir	Microbial Culture
Triacetyl-ganciclovir is a Ganciclovir derivative. Ganciclovir is an orally active antiviral agent with activity against cytomegalovirus (CMV) .

HY-B0434G

Ribavirin (GMP) Ribasphere (GMP); ICN-1229 (GMP)	Biochemical Assay Reagents
Ribavirin (GMP) is Ribavirin (HY-B0434) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.

Cat. No.	Product Name	Target	Research Area

HY-16050

Plitidepsin 2 Publications Verification Aplidine; PM90001	DNA/RNA Synthesis SARS-CoV	Infection Cancer
Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( K_D=80 nM) . Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC₉₀ of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research .

HY-P4307

Antioxidant agent-9	SARS-CoV	Infection
Antioxidant agent-9 is a peptide with the sequence Asp-Trp. Antioxidant agent-9 shows antioxidant activity. Antioxidant agent-9 also is potential as SARS-CoV-2 antiviral, with an affinity strength equal to Chloroquine (HY-17589A) and Favipiravir (HY-14768) .

HY-P2015

Berlopentin Diacetylsplenopentine	Peptides	Infection Inflammation/Immunology
Berlopentin (Diacetylsplenopentine) is an antiviral agent, and protects guinea pigs from foot-and-mouth disease (FMD) infection. Berlopentin has immunostimulatory properties .

HY-P3223

Biphalin TFA	Opioid Receptor	Neurological Disease
Biphalin TFA, a BBB-penetrable opioid peptide analog, contains two active enkephalin pharmacophores. Biphalin TFA has high affinity for opioid receptors. Biphalin TFA shows analgesic effect in acute, neuropathic, and chronic animal pain models. Biphalin TFA is also an antiviral, antiproliferative, anti-inflammatory, and neuroprotective agent .

HY-P3626

Astodrimer SPL7013 free base	Bacterial HCV SARS-CoV	Infection
Astodrimer (SPL7013 free base) is a large (3-4 nm, ~ 16.5 kDa), negatively charged, highly-branched dendrimer, is a potent virucidal agent. Astodrimer shows antiviral and virucidal activity against a broad spectrum of viruses, including SARS-CoV-2, HIV-1, HSV-1, HSV-2, HPV. Astodrimer also has antibacterial properties .

HY-16050R

Plitidepsin (Standard)	DNA/RNA Synthesis SARS-CoV	Infection Cancer
Plitidepsin (Standard) is the analytical standard of Plitidepsin. This product is intended for research and analytical applications. Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( K_D=80 nM) . Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC₉₀ of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0359

Cynarin 2 Publications Verification Cynarine	Phyllodium pulchellum (L.) Desv. Structural Classification Classification of Application Fields Source classification Other Phenylpropanoids Phenols Polyphenols Phenylpropanoids Plants Compositae Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species Influenza Virus
Cynarin is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities.

HY-I0660

Picolinic acid PCL 016	Infection Structural Classification Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite Virus Protease
Picolinic acid (PCL 016) is a topical antiviral agent, which inhibits adenovirus replication in rabbits.

HY-N2268

Gymnemagenin	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Asclepiadaceae Metabolic Disease Plants Disease Research Fields Gymnema sylvestre (Retz.) Schult.	Antibiotic
Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties .

HY-17427

Emtricitabine 5 Publications Verification BW1592	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	HIV Reverse Transcriptase Endogenous Metabolite
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC₅₀ of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.

HY-N12691

Antiviral agent 51	Structural Classification Marine natural products Source classification Saccharides Monosaccharides	Dengue virus
Antiviral agent 51 (compound a) is a potent antiviral agent. Antiviral agent 51 is a fucoidan. Antiviral agent 51 interacts with DENV-2 RNA Dependant RNA polymerase (RdRp) .

HY-N12362

Antiviral agent 41	Structural Classification Monophenols Source classification Phenols Alpinia officinarum Hance Plants Zingiberaceae	Influenza Virus
Antiviral agent 41 (compound 5) is a diarylheptanoid isolated from Alpinia officinarum. Antiviral agent 41 exhibits potential antiviral activity against influenza virus in vitro .

HY-119748

Sageone	Structural Classification Labiatae Source classification Phenols Polyphenols Plants Pteris semipinnata L. Sp.	Others
Sageone, a diterpene that can be isolated from Rosmarinus officinalis, is a antiviral and anticancer agent .

HY-119458

Luotonin A	Structural Classification Alkaloids Peganum nigellastrum Bunge Zygophyllaceae Source classification Quinoline Alkaloids Plants	Topoisomerase TMV Fungal
Luotonin A is an *antiviral* and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV). Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity .

HY-N0191A

14-epi-Andrographolide 14-Epiandrographolide	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	Others
14-epi-andrographolide is a diterpene analog of Andrographolide (HY-N0191), which is an NF-κB inhibitor and antiviral agent .

HY-N0359R

Cynarin (Standard)	Phyllodium pulchellum (L.) Desv. Structural Classification Source classification Other Phenylpropanoids Phenols Polyphenols Phenylpropanoids Plants Compositae	Reactive Oxygen Species Influenza Virus
Cynarin (Standard) is the analytical standard of Cynarin. This product is intended for research and analytical applications. Cynarin is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities.

HY-N8265

Abyssinone V	Structural Classification Flavonoids Leguminosae Flavonones Source classification Erythrina melanacantha Taub. ex Harms Plants	HSV DNA/RNA Synthesis ATP Synthase
Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity .

HY-N2268R

Gymnemagenin (Standard)	Triterpenes Structural Classification Terpenoids Source classification Asclepiadaceae Plants Gymnema sylvestre (Retz.) Schult.	Antibiotic
Gymnemagenin (Standard) is the analytical standard of Gymnemagenin. This product is intended for research and analytical applications. Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties .

HY-17427R

Emtricitabine (Standard) BW1592 (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	HIV Reverse Transcriptase Endogenous Metabolite
Emtricitabine (Standard) is the analytical standard of Emtricitabine. This product is intended for research and analytical applications. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC₅₀ of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.

HY-114275

Justicidin B	Structural Classification Acanthaceae Source classification Lignans Justicia procumbens Linnaeus Phenylpropanoids Plants	Fungal Parasite Apoptosis
Justicidin B is a potent anticancer lignan and proapoptotic agent. Justicidin B is also a bone resorption inhibitor, and has strong antiviral, fungicidal, antiprotozoal effects. Justicidin B significantly inhibits platelet aggregation .

HY-B0421

Mycophenolic acid 5+ Cited Publications Mycophenolate	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Dengue virus Apoptosis Bacterial Fungal Endogenous Metabolite Antibiotic Flavivirus
Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC₅₀ of 0.24 µM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects .

HY-N7677

Isookanin	Structural Classification Classification of Application Fields Source classification Plants Compositae Infection Flavonoids Deguelia rufescens (Benth.) R.A.Camargo & A.M.G.Azevedo Flavonones Phenols Polyphenols Inflammation/Immunology Disease Research Fields	HSV
Isookanin can be used for the research of various illnesses including cancers, skin rashes, snake and insects bites, diabetes mellitus, diarrhoea. Isookanin acts as an anti-viral agent against HSV and varicella-zoster virus (VZV). Antioxidant activity .

HY-B0421A

Mycophenolic acid sodium 5+ Cited Publications Mycophenolate sodium	Infection Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	Dengue virus Apoptosis Bacterial Fungal Antibiotic Endogenous Metabolite Flavivirus
Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC₅₀ of 0.24 µM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects .

HY-N0035

Arctigenin 5+ Cited Publications (-)-Arctigenin	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Lignans Metabolic Disease Plants Compositae Caesalpinia magnifoliolata Metc. Endogenous metabolite Infection Human Gut Microbiota Metabolites Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	MMP Influenza Virus Autophagy Apoptosis
Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .

HY-17425A

Valacyclovir hydrochloride 1 Publications Verification Valaciclovir hydrochloride	Infection Classification of Application Fields Disease Research Fields	HSV Antibiotic Bacterial
Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active *antiviral* agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (₅₀=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) .

HY-W012634

Benzothiazole	Microorganisms Source classification	Bacterial
Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent ^[1][2][3][4].

HY-N11097

FK-3000	Structural Classification Alkaloids Piperidine Alkaloids Source classification Plants Stephania delavayi Diels Menispermaceae	Apoptosis HSV HIV
FK-3000 is a potent anti-tumor agent that inhibits the growth of carcinoma cells through apoptosis and induction cell cycle arrest. FK-3000 also exhibit antiviral effects against HSV-1 and HIV-1 .

HY-119728

FR198248	Structural Classification Microorganisms Source classification Phenols Polyphenols	Influenza Virus
FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC₅₀ of 3.6 µM. FR198248 can be used for antiviral and antibacterial research .

HY-N6715

Tenuazonic acid	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Biological Pesticide Research Agricultural Research	Influenza Virus Bacterial Enterovirus
Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a *photosystem II (PSII)* inhibitor that can act as a potential herbicide. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid induces fungal poisoning in mice. Tenuazonic acid has an inhibitory effect on skin cancer .

HY-B0277

Vidarabine 5 Publications Verification Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine	Infection Structural Classification Microorganisms Antibiotics Source classification Antiviral Antibacterial Disease Research Disease Research Fields	HSV Nucleoside Antimetabolite/Analog Orthopoxvirus Antibiotic
Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses . Vidarabine has IC₅₀s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2 . Vidarabine also has anti-orthopoxvirus activity .

HY-N12697A

Polycarpine hydrochloride	Structural Classification Alkaloids Animals Other Alkaloids Source classification	SARS-CoV Virus Protease Influenza Virus Fungal
Polycarpine hydrochloride (1a) is a broad-spectrum Mpro inhibitor (IC₅₀ = 30 nM) that can be isolated from the Polycarpa aurata and also serves as an anti-coronaviral agent. Polycarpine hydrochloride possesses antiviral and antifungal activities, with IC₅₀ values of 30.0 nM and 0.12 μM against SARS-CoV-2 Mpro and PEDV Mpro, respectively .

HY-B0421R

Mycophenolic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Dengue virus Apoptosis Bacterial Fungal Endogenous Metabolite Antibiotic Flavivirus
Mycophenolic acid (Standard) is the analytical standard of Mycophenolic acid. This product is intended for research and analytical applications. Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM.?Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects .

HY-B0421AR

Mycophenolic acid sodium (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite	Dengue virus Apoptosis Bacterial Fungal Antibiotic Endogenous Metabolite Flavivirus
Mycophenolic acid (sodium) (Standard) is the analytical standard of Mycophenolic acid (sodium). This product is intended for research and analytical applications. Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects .

HY-16050

Plitidepsin 2 Publications Verification Aplidine; PM90001	Structural Classification Microorganisms Marine natural products Source classification Other marine organisms	DNA/RNA Synthesis SARS-CoV
Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( K_D=80 nM) . Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC₉₀ of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research .

HY-N0035R

Arctigenin (Standard)	Structural Classification Human Gut Microbiota Metabolites Source classification Lignans Phenylpropanoids Plants Compositae Caesalpinia magnifoliolata Metc. Endogenous metabolite	MMP Influenza Virus Autophagy Apoptosis
Arctigenin (Standard) is the analytical standard of Arctigenin. This product is intended for research and analytical applications. Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .

HY-W012634R

Benzothiazole (Standard)	Microorganisms Source classification	Bacterial
Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .

HY-B0277R

Vidarabine (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antiviral Antibacterial Disease Research	HSV Nucleoside Antimetabolite/Analog Orthopoxvirus Antibiotic
Vidarabine (Standard) is the analytical standard of Vidarabine. This product is intended for research and analytical applications. Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses . Vidarabine has IC₅₀s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2 . Vidarabine also has anti-orthopoxvirus activity .

HY-16050R

Plitidepsin (Standard)	Structural Classification Microorganisms Marine natural products Source classification Other marine organisms	DNA/RNA Synthesis SARS-CoV
Plitidepsin (Standard) is the analytical standard of Plitidepsin. This product is intended for research and analytical applications. Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( K_D=80 nM) . Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC₉₀ of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research .

HY-W010649

Isoxazole	Classification of Application Fields Disease Research Fields Cancer	Antibiotic HSP
Isoxazole possesses broad biological activities with low cytotoxicity (e.g. anti-microbial, antibacterial, antifungal, anti-viral, anti-cancer, anti-inflammatory, immunomodulatory, analgesic, antituberculous or anti-diabetic properties), which is a member of five-membered heterocycles for a agent scaffold. Isoxazole with reversed ring can be used as HSP90 inhibitor. Isoxazole has been explored as BET bromodomain inhibitor and tricyclic Isoxazole is a promising for selective multidrug resistance protein (MRP1) inhibitors. Isoxazole is promising for research of various inhibitors and diseases .

HY-N1992

Theaflavin 3,3'-digallate 5 Publications Verification TF-3; ZP10	Infection Structural Classification Flavonoids Classification of Application Fields Flavanols Source classification Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Disease Research Fields Theaceae	Virus Protease HSV HIV Flavivirus
Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC₅₀ of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (K_d=8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1 . Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent .

HY-15310

Ivermectin Maximum Cited Publications 24 Publications Verification MK-933; CD-5024; K-237	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antiviral Anti-parasitic Disease Research Disease Research Fields Cancer	Flavivirus Dengue virus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

HY-N1992R

Theaflavin 3,3'-digallate (Standard)	Structural Classification Flavonoids Flavanols Source classification Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Theaceae	Virus Protease HSV HIV Flavivirus
Theaflavin 3,3'-digallate (Standard) is the analytical standard of Theaflavin 3,3'-digallate. This product is intended for research and analytical applications. Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC₅₀ of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (Kd=8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1 . Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent .

HY-15310R

Ivermectin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Antiviral Anti-parasitic Disease Research	Dengue virus Flavivirus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial
Ivermectin (Standard) is the analytical standard of Ivermectin. This product is intended for research and analytical applications. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

Cat. No.	Product Name	Chemical Structure

HY-N0453S

Hypericin-d10
Hypericin-d₁₀ is the deuterium labeled Hypericin. Hypericin is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum. It can inhibit tyrosine kinases with IC50 of 7.5 μM.

HY-B0402S

Amantadine-d15
Amantadine-d₁₅ is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent[1][2].

HY-17427S

Emtricitabine-15N,d2
Emtricitabine- ¹⁵N,d₂ is a ¹⁵N-labeled and deuterium labeled Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.

HY-17425AS

Valacyclovir-d8 hydrochloride
Valacyclovir-d₈ (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) [1][2][3][4][5].

HY-17426S

Famciclovir-d4
Famciclovir-d₄ is the deuterium labeled Famciclovir. Famciclovir (BRL 42810) is a guanine analogue antiviral agent used for the treatment of various herpesvirus infections[1][2].

HY-B0434S

Ribavirin-13C5
Ribavirin- ¹³C₅ is the ¹³C-labeled Ribavirin. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV.

HY-B1826S2

Adefovir-d4
Adefovir-d₄ is the deuterium labeled Adefovir. Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses[1][2][3].

HY-W008351S

L-Ribose-13C
L-Ribose- ¹³C is the ¹³C labeled L-Ribose. L-Ribose, a non-naturally occurring pentose, is an ideal starting material for use in synthesizing L-nucleosides analogues. Many anticancer and antiviral agents are synthesized based on a backbone of L-Ribose and i

HY-B0434S1

Ribavirin-15N, d2
Ribavirin- ¹⁵N, d2 is ¹⁵N and deuterated labeled Ribavirin (HY-B0434). Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.

HY-17425AS1

Valacyclovir-d4 hydrochloride
Valacyclovir-d₄ (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422)[1][2][3][4][5].

HY-17427S2

Emtricitabine-13C,15N2
Emtricitabine- ¹³C, ¹⁵N₂ (BW1592- ¹³C, ¹⁵N₂) is a ¹³C- and ¹⁵N-labeled Emtricitabine (HY-17427). Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC₅₀ of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.

HY-A0061S

Trifluridine-13C,15N2
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].

HY-14904AS

Umifenovir-d6 hydrochloride

Umifenovir-d₆ (hydrochloride) is the deuterium labeled Umifenovir hydrochloride. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3].

HY-B0421S2

Mycophenolic acid-13C17

Mycophenolic acid-13C17 (Mycophenolate-13C17) is the 13C labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects.

HY-106161S1

Rupintrivir-d7

Rupintrivir-d7 is a deuterated labeled Rupintrivir . Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀ of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

HY-W653905

Amantadine-d15 hydrochloride

Amantadine-d₁₅ hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .

HY-B0402S1

Amantadine-d6

Amantadine-d₆ is the deuterium labeled Amantadine[1]. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research[2][3][4][5][6][7].

HY-16305S1

Maribavir-d6 TFA
Maribavir-d6 TFA (1263W94-d6 TFA; BW1263W94-d6 TFA; GW257406X-d6 TFA) is a deuterium labeled Maribavir (HY-16305). Maribavir is an orally active antiviral agent for cytomegalovirus (CMV) through inhibition of protein kinase UL97 and the following CMV DNA replication .

HY-17422S1

Acyclovir-d4

Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

HY-13637S

Ganciclovir-d5

Ganciclovir-d₅ is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1)[1][2][3].

Cat. No.	Product Name		Classification

HY-149057

Neuraminidase-IN-12		Azide
NDV-IN-1 is an antiviral agent with high neuraminidase inhibitory activity. NDV-IN-1 exhibits in vitro inhibitory activity against Newcastle disease virus (NDV). NDV-IN-1 significantly inhibits NDV infection of Vero cells by preventing the release of virus particles from infected cells . Neuraminidase-IN-12 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-145273

EB-0150		Azide
EB-0150 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC₅₀s of 0.73 and 0.0337 μM, respectively. EB-0150 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0150 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses . EB-0150 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-121513

Torcitabine 2'-Deoxy-L-cytidine; L-dC		Nucleosides and their Analogs
Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine has the potential for chronic hepatitis B virus infection treatment .

HY-109528

Fomivirsen sodium ISIS-2922		Antisense Oligonucleotides
Fomivirsen (ISIS-2922) sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen sodium is an **antiviral agent that is used cytomegalovirus retinitis (CMV)** research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein, thus inhibiting virus proliferation .

HY-138577

2'-F-Bz-dC Phosphoramidite		Nucleoside Phosphoramidites
2'-F-Bz-dC Phosphoramidite can be used in the synthesis of oligoribonucleotide (such as DNA and RNA). 2'-F-Bz-dC Phosphoramidite also used for synthesis antiviral agent to inhibit the replication of virus. 2'-F-Bz-dC Phosphoramidite contains a phosphorothioate backbone, to synthesise antisense oligonucleotide analogs to induce apoptosis in cancer cells .

HY-147321

3'-DMTr-dG(iBu)		Nucleosides and their Analogs
3'-DMTr-dG(iBu) is a nucleoside for the synthesis of nucleic acid, such as antiviral agents used in the research of viral infection (HBV, HDV), and oligonucleotides against Alzheimer’s disease and other tauopathies .

HY-141893

3-Cyanovinylcarbazole phosphoramidite		Nucleoside Phosphoramidites
3-Cyanovinylcarbazole phosphoramidite is an antiviral agent that inhibits the synthesis of viral DNA. The modified nucleoside in the compound is synthesized by modifying the ribonucleotide with cyano group at the C-3 position, and can be used as a phosphoric acid amide for DNA synthesis .

HY-152437

3’-Amino-3’-deoxy-5-methyl uridine		Nucleosides and their Analogs
3’-Amino-3’-deoxy-5-methyl uridine, Anticancer antiviral agent is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-148170

L-I-OddU		Nucleosides and their Analogs
L-I-OddU, a L-5'-halo- dioxolane nucleoside analogue, is a potent and selective anti-Epstein-Barr virus (EBV) agent with an EC₅₀ value of 0.03μM. L-I-OddU has low cytotoxicity with a CC₅₀ value of 1000 nM. L-I-OddU has antiviral activity by suppressing replicative EBV DNA and viral protein synthesis .

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