Search Result

Isoforms Recommended:	IL-17

Results for "

il17

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (1) Apoptosis (1) Calcium Channel (3) DNA/RNA Synthesis (2) Epigenetic Reader Domain (1) Histone Acetyltransferase (1) IFNAR (2) Interleukin Related (52) Lipoxygenase (1) MMP (1) NF-κB (1) Platelet-activating Factor Receptor (PAFR) (1) ROR (22) Small Interfering RNA (siRNA) (13) STAT (1) TNF Receptor (5) Toll-like Receptor (TLR) (3) TRP Channel (3)
By Research Areas:	Cancer (19) Infection (3) Inflammation/Immunology (79) Neurological Disease (7)
Oligonucleotides:	Pre-designed siRNA Sets (13) Antisense Oligonucleotides (2) siRNAs (13)

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141692

IL-17 modulator 4	Interleukin Related	Inflammation/Immunology Cancer
IL-17 modulator 4 is a proagent of IL-17 modulator 1 (HY-141535). IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator. IL-17 modulator 4 is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome .

HY-139203

IL-17 modulator 3	Interleukin Related	Inflammation/Immunology Cancer
IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases .

HY-141535A

IL-17 modulator 1 disodium	Interleukin Related	Infection Inflammation/Immunology
IL-17 modulator 1 (disodium) is an orally active, highly efficacious IL-17 modulator extracted from patent WO 2020127685. IL-17 modulator 1 (disodium) can be used for the research of diseases including psoriasis, ankylosing spondylitis and psoriatic arthritis .

HY-134371

IL-17 modulator 2	Interleukin Related	Inflammation/Immunology
IL-17 modulator 2 (compound 159) is an orally active modulator of *IL-17. IL-17* modulator 2 significantly reduces IL-6, IFN-γ, and edema. IL-17 modulator 2 can used in study arthritis .

HY-160026

IL-17 modulator 8	Interleukin Related	Inflammation/Immunology
IL-17 modulator 8 (compound 286) is an orally active modulator of *IL-17. IL-17* modulator 8 significantly reduces IL-6, IFN-γ, and edema. IL-17 modulator 8 can used in study arthritis .

HY-160028

IL-17 modulator 9	Interleukin Related	Inflammation/Immunology
IL-17 modulator 9 (compound 453) is an orally active modulator of *IL-17. IL-17* modulator 9 significantly reduces IL-6, IFN-γ, and edema. IL-17 modulator 9 can used in study inflammation .

HY-144373

IL-17 modulator 6	Interleukin Related	Inflammation/Immunology
IL-17 modulator 6 (compound 61) is a potent *Interleukin 17 (IL-17)* modulator (pIC₅₀=9.1). IL-17 modulator 6 has the ability to inhibit IL-17 and can be used for the research of inflammatory and autoimmune diseases .**

HY-141692A

IL-17 modulator 4 sulfate	Interleukin Related	Inflammation/Immunology
IL-17 modulator 4 sulfate is a proagent of IL-17 modulator 1 (HY-141535). IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator .

HY-145434

IL-17 modulator 5	Interleukin Related	Inflammation/Immunology
IL-17 modulator 5 (compound 26) is a *IL-17* inhibitor, with an IC₅₀ of 1 nM .

HY-141535

IL-17 modulator 1	Interleukin Related	Infection Inflammation/Immunology
IL-17 modulator 1 is an orally active, highly efficacious small molecule IL-17 modulators extracted from patent WO 2020127685. IL-17 modulator 1 can be used for the research of preventing, researching or ameliorating a variety of diseases including psoriasis, ankylosing spondylitis and psoriatic arthritis .

HY-168582

IL-17-IN-2	Interleukin Related	Inflammation/Immunology
IL-17-IN-2 (Example 51) is a potent inhibitor of *IL-17, with the IC₅₀* of < 0.4 μM in HTRF and NHK assay .

HY-168084

IL-17-IN-1	Interleukin Related	Inflammation/Immunology
IL-17-IN-1 (26) is an orally active *IL-17* inhibitor, with IC₅₀ values of 0.013 μM and 0.004 μM for IL-17A and IL-6 release, respectively. IL-17-IN-1 (26) effectively reduces knee swelling in a rat arthritis model .

HY-148272

IL-17A modulator-3	Interleukin Related	Inflammation/Immunology Cancer
IL-17A modulator-3 (compound 253) is a *IL-17A* modulator. IL-17A modulator-3 inhibits IL-17A/A with an IC₅₀ value ＜10 μM. IL-17A modulator-3 can be used for the research of inflammation, cancer and autoimmune disease .

HY-145429

IL-17A modulator-2	Interleukin Related	Neurological Disease Inflammation/Immunology Cancer
IL-17A modulator-2 is a *IL-17A* modulator, extracted from patent WO2021239743+A1, example 27. IL-17A modulator-2 inhibits the biological action of IL-17A with a pIC₅₀ of 8.3. IL-17A modulator-2 can be used for the research of diseases or disorders associated with modulation of IL-17A activity including diseases with an immune component or autoimmune pathol, cancer and neurodegenerative disorders .

HY-145430

IL-17A modulator-1	Interleukin Related	Neurological Disease Inflammation/Immunology Cancer
IL-17A modulator-1 is a *IL-17A* modulator, extracted from patent WO2021239743+A1, example 9. IL-17A modulator-1 inhibits the biological action of IL-17A with a pIC₅₀ of 8.2. IL-17A modulator-1 can be used for the research of diseases or disorders associated with modulation of IL-17A activity including diseases with an immune component or autoimmune pathol, cancer and neurodegenerative disorders .

HY-101915

IL-17A antagonist 3	Interleukin Related	Inflammation/Immunology
IL-17A antagonist 3 is an *IL-17A* antagonist, compound 3 .

HY-139686

IL-17A inhibitor 2	Interleukin Related	Inflammation/Immunology
IL-17A inhibitor 2 is an *IL-17A* inhibitor for researching psoriasis, rheumatoid arthritis, and multiple sclerosis.

HY-169306

IL-17A inhibitor 4	Interleukin Related	Inflammation/Immunology
IL-17A inhibitor 4 (Example 449) is a potent *IL-17A* inhibitor. IL-17A inhibitor 4 inhibits HTRF and NHK cells viability with IC₅₀s of 0.028 and 0.0047 μM, respectively .

HY-158159

IL17A-IN-1	Interleukin Related	Inflammation/Immunology Cancer
IL17A-IN-1 (compound 72) is an orally active Interleukin 17A inhibitor. IL17A-IN-1 can be used in the study of inflammatory and autoimmune diseases (plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis, etc.), as well as cancer .

HY-101913

IL-17A antagonist 1 1 Publications Verification	Interleukin Related	Inflammation/Immunology
IL-17A antagonist 1 (compound 1) is an *IL-17A* antagonist, with a K_d of 0.66 μM and an IC₅₀ of 1.14 μM .

HY-139206

LY3509754 2 Publications Verification il-17A inhibitor 1	Interleukin Related	Inflammation/Immunology
LY3509754 (IL-17A inhibitor 1) is a *IL-17A* inhibitor, with IC₅₀ values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells .

HY-RS06695

IL17A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17A Human Pre-designed siRNA Set A contains three designed siRNAs for IL17A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17A Human Pre-designed siRNA Set A IL17A Human Pre-designed siRNA Set A

HY-RS06696

Il17a Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il17a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il17a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il17a Mouse Pre-designed siRNA Set A Il17a Mouse Pre-designed siRNA Set A

HY-RS06697

Il17a Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il17a Rat Pre-designed siRNA Set A contains three designed siRNAs for Il17a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il17a Rat Pre-designed siRNA Set A Il17a Rat Pre-designed siRNA Set A

HY-RS06698

IL17B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17B Human Pre-designed siRNA Set A contains three designed siRNAs for IL17B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17B Human Pre-designed siRNA Set A IL17B Human Pre-designed siRNA Set A

HY-RS06699

IL17C Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17C Human Pre-designed siRNA Set A contains three designed siRNAs for IL17C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17C Human Pre-designed siRNA Set A IL17C Human Pre-designed siRNA Set A

HY-RS06700

IL17D Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17D Human Pre-designed siRNA Set A contains three designed siRNAs for IL17D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17D Human Pre-designed siRNA Set A IL17D Human Pre-designed siRNA Set A

HY-RS06701

IL17F Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17F Human Pre-designed siRNA Set A contains three designed siRNAs for IL17F gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17F Human Pre-designed siRNA Set A IL17F Human Pre-designed siRNA Set A

HY-RS06702

IL17RA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17RA Human Pre-designed siRNA Set A contains three designed siRNAs for IL17RA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17RA Human Pre-designed siRNA Set A IL17RA Human Pre-designed siRNA Set A

HY-RS06703

IL17RB Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17RB Human Pre-designed siRNA Set A contains three designed siRNAs for IL17RB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17RB Human Pre-designed siRNA Set A IL17RB Human Pre-designed siRNA Set A

HY-RS06704

IL17RC Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17RC Human Pre-designed siRNA Set A contains three designed siRNAs for IL17RC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17RC Human Pre-designed siRNA Set A IL17RC Human Pre-designed siRNA Set A

HY-RS06705

IL17RD Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17RD Human Pre-designed siRNA Set A contains three designed siRNAs for IL17RD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17RD Human Pre-designed siRNA Set A IL17RD Human Pre-designed siRNA Set A

HY-RS06706

IL17RE Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17RE Human Pre-designed siRNA Set A contains three designed siRNAs for IL17RE gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17RE Human Pre-designed siRNA Set A IL17RE Human Pre-designed siRNA Set A

HY-RS06707

IL17REL Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17REL Human Pre-designed siRNA Set A contains three designed siRNAs for IL17REL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17REL Human Pre-designed siRNA Set A IL17REL Human Pre-designed siRNA Set A

HY-141692B

*(R)-IL-17* modulator 4**	Interleukin Related	Inflammation/Immunology
(R)-IL-17 modulator 4 is the R-configure of IL-17 modulator 4 (HY-141692). IL-17 modulator 4 is a proagent of IL-17 modulator 1 (HY-141535). IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator .

HY-P99335

Vunakizumab Anti-Human il17A Recombinant Antibody	Interleukin Related	Inflammation/Immunology
Vunakizumab (Anti-Human IL17A Recombinant Antibody) is a recombinant human IgGκ monoclonal antibody that targets IL-17A and inhibits its interaction with the IL-17 receptor. Vunakizumab can be used to study autoimmune diseases such as psoriatic arthritis, ankylosing spondylitis, multiple sclerosis and inflammatory arthritis .

HY-19770

GSK2981278 3 Publications Verification	ROR	Inflammation/Immunology
GSK2981278 is a potent and selective RORγ inverse agonist. GSK2981278 inhibits activation of the il17 promoter and interferes RORγ-DNA binding .

HY-123505

Dersalazine sodium UR-12746 sodium	Platelet-activating Factor Receptor (PAFR) Interleukin Related	Inflammation/Immunology
Dersalazine (sodium) is a platelet-activating factor (PAF) antagonist. Dersalazine (sodium) can exert intestinal anti-inflammatory activity in rodent colitis models by downregulating *IL-17* expression .

HY-19775

GNE-6468	ROR	Inflammation/Immunology
GNE-6468 is a highly potent and selective RORγ (RORc) inverse agonist with an EC₅₀ value of 13 nM for HEK-293 cell. GNE-6468 exhibits an EC₅₀ of 30 nM for IL-17 PBMC .

HY-131397

Docosahexaenoyl serotonin DHA-5-HT	Interleukin Related	Inflammation/Immunology
Docosahexaenoyl serotonin (DHA-5-HT) is an endogenous n-3 fatty acid-serotonin conjugate. Docosahexaenoyl serotonin is an inhibitor of *IL-17*. Docosahexaenoyl serotonin has anti-inflammatory activity .

HY-P9924

Ixekizumab LY2439821	Interleukin Related	Inflammation/Immunology
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin *IL-17A* (K_D<3 pM). Ixekizumab directly blocks IL-17A binding to IL-17RA (IL-17A receptor) but does not bind to other IL-17 family members. Ixekizumab is used for the research of moderate-to-severe plaque psoriasis .

HY-111366

CD12681	ROR	Inflammation/Immunology
CD12681 (compound 14) is a potent and selective RORγ inverse agonist with IC₅₀ of 19 nM and 10 nM for RORγ GAL4 and CD4-IL-17 cells, respectively. CD12681 decreases the IL-17 inflammatory cell recruitment. CD12681 has the potential for the research of psoriasis .

HY-160040

Cobitolimod	Toll-like Receptor (TLR)	Inflammation/Immunology
Cobitolimod is a DNA oligonucleotide agonist of TLR-9 with anti-inflammatory activity. Cobitolimod suppresses Th17 cells and induces anti-inflammatory FoxP3 and IL-10 expression, inhibiting the IL-17 signaling pathway .

HY-160040A

Cobitolimod sodium	Toll-like Receptor (TLR)	Inflammation/Immunology
Cobitolimod sodium is a DNA oligonucleotide agonist of TLR-9 with anti-inflammatory activity. Cobitolimod sodium inhibits Th17 cells and induces anti-inflammatory FoxP3 and IL-10 expression, inhibiting the IL-17 signaling pathway .

HY-128573

RORγt Inverse agonist 3	ROR	Neurological Disease
RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC₅₀s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively .

HY-101454

SR0987 2 Publications Verification	ROR	Inflammation/Immunology Cancer
SR0987, a SR1078 analog, is a RORγt agonist, with an EC₅₀ of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1 .

HY-142806

RORγt inverse agonist 26	ROR	Inflammation/Immunology
RORγt inverse agonist 26 is a potent reverse agonist of RORγt. RORγt inverse agonist 26 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 26 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 1) .

HY-142703

RORγt inverse agonist 28	ROR	Inflammation/Immunology
RORγt inverse agonist 28 is a potent reverse agonist of RORγt. RORγt inverse agonist 28 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 28 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 6) .

HY-120785

SR1555	ROR	Inflammation/Immunology
SR1555 is a specific retinoic acid receptor-related orphan nuclear receptor γ (RORγ) inverse agonist with an IC₅₀ value of 1 μM. SR1555 not only inhibits TH17 cell development and function but also increases the frequency of T regulatory cells, as well as inhibits the expression of IL-17. SR1555 can be used for researching autoimmune diseases .

HY-N9965

2'-Fucosyllactose 2'-FL	TNF Receptor Interleukin Related	Infection Inflammation/Immunology
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines .

Cat. No.	Product Name

HY-L156

Autoimmune Disease Compound Library

500 compounds

Autoimmune disease is a pathological disease characterized by inflammatory disorders targeting autoantigens. The routine treatment of autoimmune diseases suppresses general immune function to regulate uncontrolled inflammation. The current targeted immunotherapy suppresses the main pro-inflammatory signaling pathways by blocking inflammatory cytokines, cell surface molecules, and intracellular kinases. As key participants in innate immunity, macrophages and dendritic cells (DCs) are crucial for Ag presentation and pro-inflammatory cytokine production, such as TNF and IL-1 β、 IL-6, IL-23, B cell activating factor (BAFF), and the proliferation-inducing ligand (APRIL, also known as TNFSF13A).

MCE designs a unique collection of 500 autoimmune disease-related compounds, covering multiple targets and subtypes, such as TNF Receptor, IFNAR, JAK, Btk, TLR, IL-6, IL-17, IL-23, etc. It is a useful tool for screening autoimmune disease drugs.

Cat. No.	Product Name	Target	Research Area

HY-P99335

Vunakizumab Anti-Human il17A Recombinant Antibody	Interleukin Related	Inflammation/Immunology
Vunakizumab (Anti-Human IL17A Recombinant Antibody) is a recombinant human IgGκ monoclonal antibody that targets IL-17A and inhibits its interaction with the IL-17 receptor. Vunakizumab can be used to study autoimmune diseases such as psoriatic arthritis, ankylosing spondylitis, multiple sclerosis and inflammatory arthritis .

HY-P9924

Ixekizumab LY2439821	Interleukin Related	Inflammation/Immunology
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin *IL-17A* (K_D<3 pM). Ixekizumab directly blocks IL-17A binding to IL-17RA (IL-17A receptor) but does not bind to other IL-17 family members. Ixekizumab is used for the research of moderate-to-severe plaque psoriasis .

HY-P99248

Risankizumab Risankizumab rzaa; BI 655066	Interleukin Related	Inflammation/Immunology
Risankizumab (BI 655066) is a humanised IgG monoclonal antibody, targeting IL-23 p19 subunit (K_d <10 pM) and inhibiting IL-17 production induced by human IL-23 in mouse splenocytes (IC₅₀ = 2 pM). Risankizumab can be used to research immunological and inflammatory disorders such as psoriasis vulgaris, psoriatic arthritis, generalized pustular psoriasis and erythrodermic psoriasis .

HY-P99280

Bimekizumab 1 Publications Verification Anti-Human il17A/il-17F Recombinant Antibody	Interleukin Related	Inflammation/Immunology
Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralises *IL-17A* and *IL-17F*. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation .

HY-P9927A

*Secukinumab (Anti-Human IL-17A)*	Interleukin Related	Inflammation/Immunology Cancer
Secukinumab (Anti-Human IL-17A) is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis .

HY-P990222

*Anti-Mouse IL-17A Antibody (17F3)*	Inhibitory Antibodies	Others
Anti-Mouse IL-17A Antibody (17F3) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to mouse IL-17A.

HY-P99652

Gumokimab AK 111	Interleukin Related	Inflammation/Immunology
Gumokimab (AK 111) is a monoclonal antibody targeting *IL-17A, which can be used in the study of psoriasis, ankylosing spondylitis. Gumokimab competitively blocks the binding of human IL-17A* to *IL-17R*.

HY-P99424

Afasevikumab RG 7624; RO 5553110; NI-1401	Interleukin Related	Inflammation/Immunology
Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities .

HY-P990221

*Anti-Mouse IL-17F Antibody (MM17F8F5.1A9)*	Inhibitory Antibodies	Others
Anti-Mouse IL-17F Antibody (MM17F8F5.1A9) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to mouse IL-17F.

HY-P990741

Galvokimig	Interleukin Related	Inflammation/Immunology
Galvokimig is an anti-IL13/IL17A/ALB/IL17B monoclonal antibody .

HY-P99940

Remtolumab ABT-122	TNF Receptor Interleukin Related	Inflammation/Immunology
Remtolumab (ABT-122) is a dual-variable domain immunoglobulin that neutralises both tumor necrosis factor α (TNFα) and *IL-17A. Remtolumab shows dual inhibition of TNFα and IL-17*A. Remtolumab can be used for rheumatoid arthritis (RA) research .

HY-P99397

Sonelokimab ALX 0761; M 1095	Interleukin Related MMP	Inflammation/Immunology
Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized *IL-17F* antibodies, *IL-17A/F* antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis .

HY-P9927

Secukinumab 2 Publications Verification AIN457	Interleukin Related	Inflammation/Immunology Cancer
Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis .

HY-P99515

Xeligekimab GR 1501	Interleukin Related	Inflammation/Immunology
Xeligekimab (GR 1501) is an anti-human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade .

HY-P99310

Perakizumab RG4934	Interleukin Related	Inflammation/Immunology
Perakizumab (RG4934) is a humanized IgG1κ monoclonal antibody against *IL-17A* (Interleukin Related). Perakizumab can be uesd for the research of autoimmune diseases, such as psoriatic arthritis .

HY-P99563

Tibulizumab LY 3090106	TNF Receptor Interleukin Related	Inflammation/Immunology
Tibulizumab (LY 3090106) is a tetravalent bispecific monoclonal antibody targeting B-cell activating factor (BAFF) and IL-17A with Kd values of 60 pM and 14 pM, respectively. Tibulizumab can be used for autoimmune disease research .

HY-P990562

CAT-2200	Inhibitory Antibodies	Inflammation/Immunology
CAT-2200 is a humanized antibody expressed in CHO, targeting *CTLA-8/IL-17a*. CAT-2200 is equipped with huIgG1 heavy chain and huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for CAT-2200 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990386

*Anti-CTLA-8/IL-17a Antibody*	Inhibitory Antibodies	Inflammation/Immunology

HY-P99754

Netakimab	Interleukin Related	Inflammation/Immunology
Netakimab is an anti-IL-17 monoclonal antibody. Nerelimomab can be used for research of ankylosing spondylitis, psoriatic arthritis, moderate-to-severe plaque psoriasis .

HY-P990761

Roconkibart	Interleukin Related	Inflammation/Immunology
Roconkibart is an anti-IL17A human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

Recombinant Proteins Recommended:

IL-17

Species:	Human (36) Marmoset (1) Rhesus Macaque (6) Mouse (28) Rat (7) Cynomolgus (3) Rabbit (3) Canine (4) Pig (2)
Tag:	His (54) Tag Free (17) Avi (14) Myc (1) Fc (18)
Source:	HEK293 (53) CHO (5) Sf9 insect cells (8) E. coli (24)

Cat. No.	Compare	Product Name	Species	Source

HY-P76418

	IL-17A Protein, Marmoset Interleukin-17A; il-17; il-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; il17A; CTLA8; il17	Marmoset	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Marmoset is a recombinant marmoset IL-17A protein is expressed in E. coli. It consists of 134 amino acids (I20-A153).

HY-P70527

	IL-17A Protein, Human (HEK293, His) 2 Publications Verification Interleukin-17A; il-17; il-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; il17A; CTLA8; il17	Human	HEK293
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Human (HEK293, His) is a recombinant human IL-17A protein with His tag at the C-terminus and is expressed in HEK293 cells. It consists of 132 amino acids (G24-A155).

HY-P70753

	IL-17A Protein, Mouse (HEK293, His) 1 Publications Verification Interleukin-17A; il-17; il-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; il17A; CTLA8; il17	Mouse	HEK293
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Mouse (HEK293, His) is a recombinant mouse IL-17A protein with His tag at the C-terminus and is expressed in HEK293 cells. It consists of 137 amino acids (T22-A158).

HY-P73170

	IL-17A Protein, Canine CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Canine	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Canine is a recombinant canine IL-17A protein and is expressed in E. coli. It consists of 130 amino acids (G26-A155).

HY-P73174

	IL-17A Protein, Mouse 5 Publications Verification CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Mouse	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Mouse is a recombinant mouse IL-17A protein and is expressed in E. coli. It consists of 137 amino acids (T22-A158).

HY-P73171

	IL-17A Protein, Human (CHO) CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Human	CHO
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Human (CHO) is a recombinant human IL-17A protein and is expressed in CHO cells. It consists of 155 amino acids (M1-A155).

HY-P73175

	IL-17A Protein, Rabbit (solution) CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Rabbit	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Rabbit (solution) is a recombinant rabbit IL-17A protein and is expressed in E. coli. It consists of 130 amino acids (G24-A153).

HY-P74833

	IL-17A Protein, Cynomolgus (sf9) CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Cynomolgus	Sf9 insect cells
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Cynomolgus (sf9) is a recombinant cynomolgus IL-17A protein and is expressed in sf9 insect cells. It consists of 155 amino acids (M1-A155).

HY-P71963

	IL-17RA Protein, Human (HEK293, hFc) CANDF5; CD217; CD217 antigen; CDw217; CTLA8; Hil 17R; hil17R; I17RA_HUMAN; il 17 receptor A; il 17 receptor; il 17RA; il-17 receptor A; il-17RA; il17; il17A receptor; il17R; il17RA; IMD51; Interleukin 17 receptor A; Interleukin-17 receptor A; MGC10262	Human	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (HEK 293, hFc) is produced in HEK293 cells with a C-Terminal hFc-tag.

HY-P72772

	IL-17A Protein, Cynomolgus (HEK293, His) Interleukin-17A; il-17; il-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; il17A; CTLA8; il17	Cynomolgus	HEK293
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus IL-17A protein with His tag at the C-terminus and is expressed in HEK293 cells. It consists of 132 amino acids (G24A155).

HY-P73176

	IL-17A Protein, Rabbit (sf9, His) CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Rabbit	Sf9 insect cells
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Rabbit (sf9, His) is a recombinant rabbit IL-17A protein with His tag at the N-terminus and is expressed in sf9 insect cells. It consists of 130 amino acids (G24-A153).

HY-P73177

	IL-17A Protein, Rhesus macaque (sf9) CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Rhesus Macaque	Sf9 insect cells
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Rhesus macaque (sf9) is a recombinant rhesus macaque IL-17A protein and is expressed in sf9 insect cells.

HY-P78320

	IL-17A Protein, Mouse (HEK293, His-Avi) CTLA-8; il17; il17A; il-17CTLA-8; interleukin 17A	Mouse	HEK293
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Mouse (HEK293, His-Avi) is a recombinant mouse IL-17A protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 133 amino acids (A26-A158).

HY-P700632

	IL-17A Protein, Pig (N-His, C-Myc) Interleukin-17A; il-17; il-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; il17A; CTLA8; il17	Pig	E. coli
	In summary, IL-17A participates in multiple immune responses and plays a critical role in maintaining epithelial barrier integrity, promoting neutrophil recruitment, and enhancing host defense against bacterial, fungal, and viral infections. IL-17A Protein, Pig (N-His, C-Myc) is the recombinant pig-derived IL-17A protein, expressed by E. coli , with C-Myc, N-10*His labeled tag. The total length of IL-17A Protein, Pig (N-His, C-Myc) is 130 a.a., with molecular weight of 22.4 kDa.

HY-P73172

	IL-17A Protein, Human (T26A, sf9, His) CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Human	Sf9 insect cells
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Human (sf9, His) is a recombinant human IL-17A protein with His tag at the N-terminus and is expressed in sf9 insect cells. It consists of 132 amino acids (G24-A155).

HY-P72576

	IL-17RE Protein, Human (HEK293, Fc) il-17 RE; il-17 receptor E; il17RE; Interleukin 17 receptor E	Human	HEK293
	Interleukin 17 receptor E (IL-17RE) is a specific functional receptor for IL-17C, and primarily expressed by epithelial cells and lymphocytes, such a Th17 cells. IL-17C/IL-17RE-axis plays a role in many inflammatory and immune diseases. IL-17RE Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P72577

	IL-17RE Protein, Mouse (HEK293, His) il-17 RE; il-17 receptor E; il17RE; Interleukin 17 receptor E	Mouse	HEK293
	Interleukin 17 receptor E (IL-17RE) is a specific functional receptor for IL-17C, and primarily expressed by epithelial cells and lymphocytes, such a Th17 cells. IL-17C/IL-17RE-axis plays a role in many inflammatory and immune diseases. IL-17RE Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 300 amino acids (A115-H414).

HY-P78157

	IL-17A Protein, Human (Biotinylated, HEK293, His-Avi) CTLA-8; il17; il17A; il-17CTLA-8; interleukin 17A	Human	HEK293
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-17A protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P78158

	IL-17A Protein, Mouse (Biotinylated, HEK293, His-Avi) CTLA-8; il17; il17A; il-17CTLA-8; interleukin 17A	Mouse	HEK293
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Mouse (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant mouse IL-17A protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 133 amino acids (A26-A158).

HY-P74832

	IL-17A/F Heterodimer Protein, Rhesus Macaque (HEK293, His) CTLA-8; il-17; Interleukin-17A; il17A; Interleukin-17F; il-17F; Cytokine ML-1	Rhesus Macaque	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F.IL-17A/F Heterodimer Protein, Rhesus Macaque (HEK293, His) is a recombinant rhesus macaque IL-17A-17F heterodimer protein with His tag at the C-terminus and is expressed in HEK293 cells.

HY-P79326

	IL-17A Protein, Rat (CHO) 1 Publications Verification il17a; interleukin 17A; il17; il-17; CTLA-8; il-17A; interleukin-17A; Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); cytotoxic T-lymphocyte-associated antigen 8; Interleukin 17	Rat	CHO
	The IL-17A protein has important heterodimerization and homodimerization activities and is involved in a variety of processes, including responses to glucocorticoid stimulation and the regulation of cell death and transcription. IL-17A is present in the cytoplasm and extracellular space and has been implicated in diseases such as pancreatitis, inflammatory bowel disease, renal disease, and periodontal disease, and may serve as a biomarker. IL-17A Protein, Rat (CHO) is the recombinant rat-derived IL-17A protein, expressed by CHO , with tag free.

HY-P73175A

	IL-17A Protein, Rabbit CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Rabbit	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Rabbit is a recombinant rabbit IL-17A protein and is expressed in E. coli. It consists of 130 amino acids (G24-A153).

HY-P78556

	IL-17A Protein, Rat (His) CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Rat	E. coli
	The IL-17A protein has important heterodimerization and homodimerization activities and is involved in a variety of processes, including responses to glucocorticoid stimulation and the regulation of cell death and transcription. IL-17A is present in the cytoplasm and extracellular space and has been implicated in diseases such as pancreatitis, inflammatory bowel disease, renal disease, and periodontal disease, and may serve as a biomarker. IL-17A Protein, Rat is the recombinant rat-derived IL-17A protein, expressed by E. coli , with tag free.

HY-P73174A

	IL-17A Protein, Mouse (E. coli) CTLA8; CTLA-8; il-17; Interleukin-17A; il17A	Mouse	E. coli
	IL-17A protein is an important effector cytokine that activates the NF-kappa-B and MAPkinase pathways through the IL17RA-IL17RC receptor complex to protect host tissues from microbial threats. As a key Th17 cytokine, IL-17A mediates neutrophil activation, chemotaxis, and contributes to germinal center formation. IL-17A Protein, Mouse (E. coli) is the recombinant mouse-derived IL-17A protein, expressed by E. coli , with tag free.

HY-P72794

	IL-17RD Protein, Mouse (CHO) Interleukin-17 receptor D; il-17 receptor D; il-17RD; mSef; il17rd; Sef	Mouse	CHO
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Mouse (CHO) is produced in CHO cells, and consists of 2713 amino acids (G29-R299).

HY-P72580

	IL-17RC Protein, Human (HEK293, Fc) Interleukin-17 receptor C; il-17 receptor C; il17RC; il17Rhom; il-17RL; ZcytoR14	Human	HEK293
	IL-17RC (Interleukin 17 receptor C), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed on a variety of nonhematopoietic cell types, and plays a role in inflammatory diseases, including autoimmunity and certain cancers. IL-17RC associates with IL-17RA to form a signaling receptor complex for IL-17A and IL-17F.IL-17RC Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P75837

	IL-17RC Protein, Human (sf9, His) Interleukin-17 receptor C; il-17 receptor C; il17RC; il17Rhom; il-17RL; ZcytoR14	Human	Sf9 insect cells
	IL-17RC (Interleukin 17 receptor C), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed on a variety of nonhematopoietic cell types, and plays a role in inflammatory diseases, including autoimmunity and certain cancers. IL-17RC associates with IL-17RA to form a signaling receptor complex for IL-17A and IL-17F. IL-17RC Protein, Human (sf9, His) is produced in Sf9 insect cells with a C-Terminal His-tag.

HY-P72583

	IL-17RA Protein, Mouse (HEK293, Fc) Interleukin-17 receptor A; il-17 receptor A; CDw217; CD217; il17RA; il17R	Mouse	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 291 amino acids (S32-W322).

HY-P77707

	IL-17A/F Heterodimer Protein, Mouse (HEK293, His-Avi) il-17A; Interleukin-17A; CTLA-8; il-17; il-17F; il24; ML-1; Interleukin-17F	Mouse	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F. IL-17A/F Heterodimer Protein, Mouse (HEK293, His-Avi) is a recombinant mouse IL-17A-17F heterodimer protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P77708

	IL-17A/F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi) il-17A; Interleukin-17A; CTLA-8; il-17; il-17F; il24; ML-1; Interleukin-17F	Mouse	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F. IL-17A/F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant mouse IL-17A-17F heterodimer protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P77713

	IL-17A/F Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi) il-17A; Interleukin-17A; CTLA-8; il-17; il-17F; il24; ML-1; Interleukin-17F	Human	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F. IL-17A/F Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-17A-17F heterodimer protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P7036

	IL-17A Protein, Human 1 Publications Verification rHuil-17; il-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8	Human	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Human is a recombinant human IL-17A protein and is expressed in E. coli. It consists of 137 amino acids (I19-A155).

HY-P70587

	IL-17D Protein, Human Interleukin-17D; il-17D; il17D	Human	E. coli
	IL-17D protein acts as a potent inducer, effectively triggering endothelial cells to express key inflammatory mediators such as IL6, CXCL8/IL8, and CSF2/GM-CSF. The ability of this cytokine to stimulate the production of pro-inflammatory signals emphasizes its importance in orchestrating immune responses, particularly in the context of endothelial cell activation. IL-17D Protein, Human is the recombinant human-derived IL-17D protein, expressed by E. coli , with tag free. The total length of IL-17D Protein, Human is 185 a.a., with molecular weight of ~20.0 kDa.

HY-P72589

	IL-17A/F Heterodimer Protein, Human (HEK293, His) il-17A/F Heterodimer; il-17A&il-17F Heterodimer	Human	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F. IL-17A/F Heterodimer Protein, Human (HEK293, His) is a recombinant human IL-17A-17F heterodimer protein with His tag at the C-terminus and is expressed in HEK293 cells.

HY-P72578

	IL-17RD Protein, Human (HEK293, His) Interleukin-17 receptor D; il-17RD; il17Rhom; hSef; il17RLM; SEF	Human	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

HY-P72579

	IL-17RD Protein, Mouse (HEK293, His) Interleukin-17 receptor D; il-17RD; il17Rhom; hSef; il17RLM; SEF	Mouse	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

HY-P75839

	IL-17RD Protein, Canine (HEK293, Fc) Interleukin-17 receptor D; il-17RD; il17Rhom; hSef; il17RLM; SEF	Canine	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P75840

	IL-17RD Protein, Canine (HEK293, His) Interleukin-17 receptor D; il-17RD; il17Rhom; hSef; il17RLM; SEF	Canine	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Canine (HEK293, His) is produced in HEK293 cells with a His-Terminal Fc-tag.

HY-P78469

	IL-17C Protein, Human (HEK293, His-Avi) CX2; Cytokine CX2; il17C; il-17C; il-17CMGC126884	Human	HEK293
	IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides.IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections.IL-17C Protein, Human (HEK293, His-Avi) is a recombinant human IL-17C protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P72581

	IL-17RB Protein, Human (HEK293, His) Interleukin-17 receptor B; il-17RB; il-17Rh1; il-17B receptor; CRL4; EVI27	Human	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

HY-P72582

	IL-17RB Protein, Mouse (HEK293, His) Interleukin-17 receptor B; il-17RB; il-17Rh1; il-17B receptor; CRL4; EVI27	Mouse	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 269 amino acids (R18-G286).

HY-P76419

	IL-17RB Protein, Human (HEK293, Fc) Interleukin-17 receptor B; il-17RB; il-17Rh1; il-17B receptor; CRL4; EVI27	Human	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P76421

	IL-17RB Protein, Mouse (HEK293, Fc) Interleukin-17 receptor B; il-17RB; il-17Rh1; il-17B receptor; CRL4; EVI27	Mouse	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 286 amino acids (M1-G286).

HY-P77404

	IL-17RB Protein, Rhesus Macaque (HEK293, His) Interleukin-17 receptor B; il-17RB; il-17Rh1; il-17B receptor; CRL4; EVI27	Rhesus Macaque	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag.

HY-P77405

	IL-17RB Protein, Rhesus Macaque (HEK293, Fc) Interleukin-17 receptor B; il-17RB; il-17Rh1; il-17B receptor; CRL4; EVI27	Rhesus Macaque	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Rhesus Macaque (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P78321

	IL-17F Protein, Mouse (HEK293, His-Avi) Cytokine ML-1; il17F; il-17F; il24; il-24; CANDF6; il-17F; ML1	Mouse	HEK293
	IL-17F is an inflammatory homodimeric cytokine that induces many proinflammatory cytokines and chemokines. IL-17F also induces antimicrobial peptides. IL-17F plays a protective role in colon cancer development and can be used for the research of autoimmune diseases, infection and cancer. IL-17F Protein, Mouse (HEK293, His-Avi) is a recombinant mouse IL-17F protein with His and Avi tags at the C-terminus and is expressed in HEK293 cells. It consists of 133 amino acids (R29-A161).

HY-P78159

	IL-17F Protein, Human (Biotinylated, HEK293, His-Avi) Cytokine ML-1; il17F; il-17F; il24; il-24; CANDF6; il-17F; ML1	Human	HEK293
	IL-17F is an inflammatory homodimeric cytokine that induces many proinflammatory cytokines and chemokines. IL-17F also induces antimicrobial peptides. IL-17F plays a protective role in colon cancer development and can be used for the research of autoimmune diseases, infection and cancer. IL-17F Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-17F protein with His and Avi tags at the C-terminus and is expressed in HEK293 cells. It consists of 133 amino acids (R31-Q163).

HY-P78160

	IL-17F Protein, Mouse (Biotinylated, HEK293, His-Avi) Cytokine ML-1; il17F; il-17F; il24; il-24; CANDF6; il-17F; ML1	Mouse	HEK293
	IL-17F is an inflammatory homodimeric cytokine that induces many proinflammatory cytokines and chemokines. IL-17F also induces antimicrobial peptides. IL-17F plays a protective role in colon cancer development and can be used for the research of autoimmune diseases, infection and cancer. IL-17F Protein, Mouse (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant mouse IL-17F protein with His and Avi tags at the C-terminus and is expressed in HEK293 cells. It consists of 133 amino acids (R29-A161).

HY-P74825

	IL-17RA Protein, Rat (HEK293, His) Interleukin-17 receptor A; il-17RA; CDw217; CD217; il17R	Rat	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Rat (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 320 amino acids (M1-P320).

HY-P74826

	IL-17RA Protein, Rat (HEK293, hFc) Interleukin-17 receptor A; il-17RA; CDw217; CD217; il17R	Rat	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Rat (HEK293, hFc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 320 amino acids (M1-P320).

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81114

	IL17A Antibody Interleukin-17A; CTLA-8; CTLA 8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated serine esterase 8; il 17A; il-17A; il-17; Interleukin 17; Interleukin-17; Interleukin 17A; Interleukin17; Interleukin17A; il17_HUMAN; il17_MOUSE.	WB, ELISA, IHC-P, IHC-F, ICC/IF	Mouse, Rat,
	IL17A Antibody is an unconjugated, approximately 15 kDa, rabbit-derived, anti-IL17A polyclonal antibody. IL17A Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in mouse, rat, background without labeling.

HY-P82900

	IL-17 Receptor A Antibody (YA2645) il17RA; il17R; Interleukin-17 receptor A; il-17 receptor A; il-17RA; CDw217; CD antigen CD217	WB, IP	Human
	IL-17 Receptor A Antibody (YA2645) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2645), targeting IL-17 Receptor A, with a predicted molecular weight of 96 kDa (observed band size: 160 kDa). IL-17 Receptor A Antibody (YA2645) can be used for WB, IP experiment in human background.

HY-P81634

	IL-17RA Antibody (YA1379) il17RA; il17R; Interleukin-17 receptor A; il-17 receptor A; il-17RA; CDw217; CD antigen CD217	FC, ELISA	Human
	IL-17RA Antibody (YA1379) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1379), targeting IL-17RA. IL-17RA Antibody (YA1379) can be used for FC, ELISA experiment in human background.