2. Gene
  3. CDC37 - cell division cycle 37, HSP90 cochaperone Gene

CDC37 - cell division cycle 37, HSP90 cochaperone Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as P50CDC37

Gene ID: 11140 | Gene type: protein coding

About CDC37

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:10,391,133-10,403,542 (from NCBI)

This gene has 10 transcripts (splice variants), 241 orthologues and 1 paralogue. Ubiquitous expression in fat (RPKM 70.6), spleen (RPKM 61.9) and 25 other tissues.

Summary

The protein encoded by this gene is highly similar to CDC 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with HSP90 and a variety of protein kinases including CDK4, CDK6, Src, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing HSP90 to its target kinases. [provided by RefSeq, Jul 2008]

CDC37 Products(1)

mRNA Protein Name
NM_007065.4 NP_008996.1 hsp90 co-chaperone Cdc37
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables heat shock protein binding IPI
IPI: Inferred from physical interaction
9660753 GOA
enables kinase binding IPI
IPI: Inferred from physical interaction
21855797 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9150368 GOA
enables scaffold protein binding IPI
IPI: Inferred from physical interaction
10409742 GOA
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within regulation of type I interferon-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
16280321 GOA
acts upstream of or within regulation of type II interferon-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
16280321 GOA
Cellular Component GO Annotation Evidence Reference Source
part of HSP90-CDC37 chaperone complex IDA
IDA: Inferred from direct assay
21855797 GOA
part of protein folding chaperone complex IDA
IDA: Inferred from direct assay
29127155 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDC37 Protein Structure

CDC37_N

CDC37_N: Cdc37 N terminal kinase binding (1 - 75)

CDC37_N

CDC37_N: Cdc37 N terminal kinase binding (77 - 127)

CDC37_M

CDC37_M: Cdc37 Hsp90 binding domain (135 - 282)

CDC37_C

CDC37_C: Cdc37 C terminal domain (286 - 357)

  • 0
  • 100
  • 200
  • 300
  • 378 a.a.
Protein Preferred Names Protein Names

hsp90 co-chaperone Cdc37

CDC37 (cell division cycle 37, S. cerevisiae, homolog)

CDC37 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CDC37 Q16543 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 NECAB2 Homo sapiens Q7Z6G3-2
Validated Y2H
32296183
Intra
CDC37 Q16543 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Array
32296183
Intra
CDC37 Q16543 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 FAM9B Homo sapiens Q8IZU0
Validated Y2H
32296183
Intra
CDC37 Q16543 FAM9B Homo sapiens Q8IZU0
Y2H Array
32296183
Intra
CDC37 Q16543 CCHCR1 Homo sapiens Q8TD31-3
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CCHCR1 Homo sapiens Q8TD31-3
Validated Y2H
32296183
Intra
CDC37 Q16543 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
32296183
Intra
CDC37 Q16543 BEND7 Homo sapiens Q8N7W2-2
Y2H Array
32296183
Intra
CDC37 Q16543 BEND7 Homo sapiens Q8N7W2-2
Validated Y2H
32296183
Intra
CDC37 Q16543 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 NRIP3 Homo sapiens Q9NQ35
Validated Y2H
32296183
Intra
CDC37 Q16543 NRIP3 Homo sapiens Q9NQ35
Y2H Array
32296183
Intra
CDC37 Q16543 NRIP3 Homo sapiens Q9NQ35
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 NT5C1A Homo sapiens Q9BXI3
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 NT5C1A Homo sapiens Q9BXI3
Validated Y2H
32296183
Intra
CDC37 Q16543 NT5C1A Homo sapiens Q9BXI3
Y2H Array
32296183
Intra
CDC37 Q16543 FKBP4 Homo sapiens Q02790
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 CDK15 Homo sapiens Q96Q40
Lumier
25036637
Intra
CDC37 Q16543 GAS8 Homo sapiens O95995
Y2H Array
32296183
Intra
CDC37 Q16543 GAS8 Homo sapiens O95995
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CCDC138 Homo sapiens Q96M89-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CCDC138 Homo sapiens Q96M89-2
Validated Y2H
32296183
Intra
CDC37 Q16543 CCDC138 Homo sapiens Q96M89-2
Y2H Array
32296183
Intra
CDC37 Q16543 GPRASP3 Homo sapiens Q6PI77
Validated Y2H
32296183
Intra
CDC37 Q16543 GPRASP3 Homo sapiens Q6PI77
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 GPRASP3 Homo sapiens Q6PI77
Y2H Array
32296183
Intra
CDC37 Q16543 CAMK2B Homo sapiens Q13554-3
Y2H Array
32296183
Intra
CDC37 Q16543 CAMK2B Homo sapiens Q13554-3
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PDE9A Homo sapiens O76083-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PDE9A Homo sapiens O76083-2
Y2H Array
32296183
Intra
CDC37 Q16543 CBY2 Homo sapiens Q8NA61-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CBY2 Homo sapiens Q8NA61-2
Validated Y2H
32296183
Intra
CDC37 Q16543 CBY2 Homo sapiens Q8NA61-2
Y2H Array
32296183
Intra
CDC37 Q16543 CARD9 Homo sapiens Q9H257-2
Y2H Array
32296183
Intra
CDC37 Q16543 CARD9 Homo sapiens Q9H257-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CARD9 Homo sapiens Q9H257-2
Validated Y2H
32296183
Intra
CDC37 Q16543 GAS7 Homo sapiens O60861-1
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 GAS7 Homo sapiens O60861-1
Y2H Array
32296183
Intra
CDC37 Q16543 CTAG1A Homo sapiens P78358
Y2H Array
32296183
Intra
CDC37 Q16543 CTAG1A Homo sapiens P78358
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 NECAB1 Homo sapiens Q8N987
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 NECAB1 Homo sapiens Q8N987
Validated Y2H
32296183
Intra
CDC37 Q16543 NECAB1 Homo sapiens Q8N987
Y2H Array
32296183
Intra
CDC37 Q16543 SYCE2 Homo sapiens Q6PIF2
Y2H Array
32296183
Intra
CDC37 Q16543 SYCE2 Homo sapiens Q6PIF2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 SYCE2 Homo sapiens Q6PIF2
Validated Y2H
32296183
Intra
CDC37 Q16543 ZNF837 Homo sapiens Q96EG3
Y2H Array
32296183
Intra
CDC37 Q16543 ZNF837 Homo sapiens Q96EG3
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ZNF837 Homo sapiens Q96EG3
Validated Y2H
32296183
Intra
CDC37 Q16543 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra
CDC37 Q16543 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra
CDC37 Q16543 CCDC91 Homo sapiens Q7Z6B0-2
Validated Y2H
32296183
Intra
CDC37 Q16543 CCDC91 Homo sapiens Q7Z6B0-2
Y2H Array
32296183
Intra
CDC37 Q16543 CCDC91 Homo sapiens Q7Z6B0-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CAMK2G Homo sapiens Q13555-5
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CAMK2G Homo sapiens Q13555-5
Y2H Array
32296183
Intra
CDC37 Q16543 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 POU6F2 Homo sapiens P78424
Y2H Array
32296183
Intra
CDC37 Q16543 CT45A1 Homo sapiens Q5HYN5
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CT45A1 Homo sapiens Q5HYN5
Validated Y2H
32296183
Intra
CDC37 Q16543 CT45A1 Homo sapiens Q5HYN5
Y2H Array
32296183
Intra
CDC37 Q16543 LZTS1 Homo sapiens Q9Y250
Validated Y2H
32296183
Intra
CDC37 Q16543 LZTS1 Homo sapiens Q9Y250
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 LZTS1 Homo sapiens Q9Y250
Y2H Array
32296183
Intra
CDC37 Q16543 APOE Homo sapiens P02649
Anti Bait CoIP
21163940
Intra
CDC37 Q16543 PRR20D Homo sapiens P86480
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PRR20D Homo sapiens P86480
Y2H Array
32296183
Intra
CDC37 Q16543 STK32A Homo sapiens Q8WU08-2
Validated Y2H
32296183
Intra
CDC37 Q16543 STK32A Homo sapiens Q8WU08-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 STK32A Homo sapiens Q8WU08-2
Y2H Array
32296183
Intra
CDC37 Q16543 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra
CDC37 Q16543 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ROPN1 Homo sapiens Q9HAT0
Validated Y2H
32296183
Intra
CDC37 Q16543 ROPN1 Homo sapiens Q9HAT0
Y2H Array
32296183
Intra
CDC37 Q16543 ROPN1 Homo sapiens Q9HAT0
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 FER Homo sapiens P16591
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 FER Homo sapiens P16591
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 CDK9 Homo sapiens P50750
TAP
24189400
Intra
CDC37 Q16543 CDK9 Homo sapiens P50750
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 ULK3 Homo sapiens Q6PHR2
Lumier
25036637
Intra
CDC37 Q16543 CAMK2A Homo sapiens Q9UQM7
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CAMK2A Homo sapiens Q9UQM7
Validated Y2H
32296183
Intra
CDC37 Q16543 CAMK2A Homo sapiens Q9UQM7
Y2H Array
32296183
Intra
CDC37 Q16543 LIMK2 Homo sapiens P53671
Lumier
25036637
Intra
CDC37 Q16543 NOS3 Homo sapiens P29474
Anti Bait CoIP
21163940
Intra
CDC37 Q16543 NOS3 Homo sapiens P29474
Pull Down
21163940
Intra
CDC37 Q16543 NOS3 Homo sapiens P29474
Y2H Array
21163940
Intra
CDC37 Q16543 REEP6 Homo sapiens Q96HR9-2
Y2H Array
32296183
Intra
CDC37 Q16543 REEP6 Homo sapiens Q96HR9-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 REEP6 Homo sapiens Q96HR9-2
Validated Y2H
32296183
Intra
CDC37 Q16543 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PIBF1 Homo sapiens Q4G0R1
Validated Y2H
32296183
Intra
CDC37 Q16543 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
CDC37 Q16543 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra
CDC37 Q16543 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra
CDC37 Q16543 RABGEF1 Homo sapiens Q9UJ41-4
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 RABGEF1 Homo sapiens Q9UJ41-4
Y2H Array
32296183
Intra
CDC37 Q16543 RABGEF1 Homo sapiens Q9UJ41-4
Validated Y2H
32296183
Intra
CDC37 Q16543 PRMT1 Homo sapiens Q99873-3
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PRMT1 Homo sapiens Q99873-3
Validated Y2H
32296183
Intra
CDC37 Q16543 PRMT1 Homo sapiens Q99873-3
Y2H Array
32296183
Intra
CDC37 Q16543 JRK Homo sapiens O75564-2
Y2H Array
32296183
Intra
CDC37 Q16543 JRK Homo sapiens O75564-2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 MOS Homo sapiens P00540
Lumier
25036637
Intra
CDC37 Q16543 CCDC152 Homo sapiens Q4G0S7
Validated Y2H
32296183
Intra
CDC37 Q16543 CCDC152 Homo sapiens Q4G0S7
Y2H Array
32296183
Intra
CDC37 Q16543 CCDC152 Homo sapiens Q4G0S7
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
CDC37 Q16543 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra
CDC37 Q16543 MID1 Homo sapiens O15344
Y2H Array
32296183
Intra
CDC37 Q16543 MID1 Homo sapiens O15344
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 TNFAIP1 Homo sapiens Q13829
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 TNFAIP1 Homo sapiens Q13829
Y2H Array
32296183
Intra
CDC37 Q16543 SSNA1 Homo sapiens O43805
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 SSNA1 Homo sapiens O43805
Y2H Array
32296183
Intra
CDC37 Q16543 BLZF1 Homo sapiens Q9H2G9
Validated Y2H
32296183
Intra
CDC37 Q16543 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra
CDC37 Q16543 GMCL1 Homo sapiens Q96IK5
Y2H Array
32296183
Intra
CDC37 Q16543 GMCL1 Homo sapiens Q96IK5
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 GMCL1 Homo sapiens Q96IK5
Validated Y2H
32296183
Intra
CDC37 Q16543 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 MIPOL1 Homo sapiens Q8TD10
Validated Y2H
32296183
Intra
CDC37 Q16543 MIPOL1 Homo sapiens Q8TD10
Y2H Array
32296183
Intra
CDC37 Q16543 CAVIN1 Homo sapiens Q6NZI2
Y2H Array
32296183
Intra
CDC37 Q16543 CAVIN1 Homo sapiens Q6NZI2
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CAVIN1 Homo sapiens Q6NZI2
Validated Y2H
32296183
Intra
CDC37 Q16543 PRKAR1B Homo sapiens P31321
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PRKAR1B Homo sapiens P31321
Y2H Array
32296183
Intra
CDC37 Q16543 LMNB2 Homo sapiens Q03252
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 LMNB2 Homo sapiens Q03252
Y2H Array
32296183
Intra
CDC37 Q16543 GRAMD2B Homo sapiens Q96HH9
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 GRAMD2B Homo sapiens Q96HH9
Validated Y2H
32296183
Intra
CDC37 Q16543 GRAMD2B Homo sapiens Q96HH9
Y2H Array
32296183
Intra
CDC37 Q16543 KRT75 Homo sapiens O95678
Y2H Array
32296183
Intra
CDC37 Q16543 KRT75 Homo sapiens O95678
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 KRT76 Homo sapiens Q01546
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 KRT76 Homo sapiens Q01546
Y2H Array
32296183
Intra
CDC37 Q16543 CDK4 Homo sapiens P11802
Anti Bait CoIP
21871133
Intra
CDC37 Q16543 CDK4 Homo sapiens P11802
GMS
27339980
Intra
CDC37 Q16543 CDK4 Homo sapiens P11802
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 CDK4 Homo sapiens P11802
3D-EM
27339980
Intra
CDC37 Q16543 CDK4 Homo sapiens P11802
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 CDK4 Homo sapiens P11802
TAP
24189400
Intra
CDC37 Q16543 CDK4 Homo sapiens P11802
Y2H
9150368
Intra
CDC37 Q16543 CDK6 Homo sapiens Q00534
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 HSP90AA1 Homo sapiens P07900
Anti Bait CoIP
21871133
Intra
CDC37 Q16543 HSP90AA1 Homo sapiens P07900
CoIP
12176997
Intra
CDC37 Q16543 HSP90AA1 Homo sapiens P07900
TAP
24189400
Intra
CDC37 Q16543 HSP90AA1 Homo sapiens P07900
Lumier
25036637
Intra
CDC37 Q16543 HSP90AA1 Homo sapiens P07900
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 AKT1 Homo sapiens P31749
CoIP
12176997
Intra
CDC37 Q16543 AKT3 Homo sapiens Q9Y243
Lumier
25036637
Intra
CDC37 Q16543 AKT3 Homo sapiens Q9Y243
CoIP
12176997
Intra
CDC37 Q16543 PSEN1 Homo sapiens P49768
Anti Bait CoIP
21163940
Intra
CDC37 Q16543 PSEN1 Homo sapiens P49768
Y2H Array
21163940
Intra
CDC37 Q16543 EGFR Homo sapiens P00533
TAP
24189400
Intra
CDC37 Q16543 EGFR Homo sapiens P00533
Lumier
25036637
Intra
CDC37 Q16543 PNMA2 Homo sapiens Q9UL42
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PNMA2 Homo sapiens Q9UL42
Validated Y2H
32296183
Intra
CDC37 Q16543 PNMA2 Homo sapiens Q9UL42
Y2H Array
32296183
Intra
CDC37 Q16543 STK11 Homo sapiens Q15831
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 SQSTM1 Homo sapiens Q13501
TAP
24189400
Intra
CDC37 Q16543 SQSTM1 Homo sapiens Q13501
Y2H Array
32296183
Intra
CDC37 Q16543 SQSTM1 Homo sapiens Q13501
Y2H
21900206
Intra
CDC37 Q16543 SQSTM1 Homo sapiens Q13501
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 IKBKE Homo sapiens Q14164
Anti Bait CoIP
17353931
Intra
CDC37 Q16543 IKBKE Homo sapiens Q14164
TAP
14743216
Intra
CDC37 Q16543 BTBD3 Homo sapiens Q9Y2F9
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 BTBD3 Homo sapiens Q9Y2F9
Validated Y2H
32296183
Intra
CDC37 Q16543 BTBD3 Homo sapiens Q9Y2F9
Y2H Array
32296183
Intra
CDC37 Q16543 FGFR3 Homo sapiens P22607
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 PRMT5 Homo sapiens O14744
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PRMT5 Homo sapiens O14744
Y2H Array
32296183
Intra
CDC37 Q16543 ACTG1 Homo sapiens P63261
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ACTG1 Homo sapiens P63261
Y2H Array
32296183
Intra
CDC37 Q16543 HSP90AB1 Homo sapiens P08238
3D-EM
27339980
Intra
CDC37 Q16543 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
22939624
Intra
CDC37 Q16543 HSP90AB1 Homo sapiens P08238
GMS
27339980
Intra
CDC37 Q16543 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 HSP90AB1 Homo sapiens P08238
TAP
24189400
Intra
CDC37 Q16543 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
26496610
Intra
CDC37 Q16543 HSP90AB1 Homo sapiens P08238
Anti Bait CoIP
11036079
Intra
CDC37 Q16543 ACTB Homo sapiens P60709
Y2H Array
32296183
Intra
CDC37 Q16543 ACTB Homo sapiens P60709
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
CDC37 Q16543 DNAJB1 Homo sapiens P25685
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 TRAF3 Homo sapiens Q13114
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 TRAF3 Homo sapiens Q13114
Y2H Array
32296183
Intra
CDC37 Q16543 PSMC6 Homo sapiens P62333
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PSMC6 Homo sapiens P62333
Y2H Array
32296183
Intra
CDC37 Q16543 TNIP1 Homo sapiens Q15025
Y2H Array
32296183
Intra
CDC37 Q16543 TNIP1 Homo sapiens Q15025
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 MAP3K14 Homo sapiens Q99558
TAP
14743216
Intra
CDC37 Q16543 MAP3K7 Homo sapiens O43318
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 MAP3K7 Homo sapiens O43318-2
TAP
14743216
Intra
CDC37 Q16543 RAF1 Homo sapiens P04049
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 RAF1 Homo sapiens P04049
Lumier
25036637
Intra
CDC37 Q16543 RAF1 Homo sapiens P04049
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 RAF1 Homo sapiens P04049
TAP
24189400
Intra
CDC37 Q16543 CARD10 Homo sapiens Q9BWT7
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CARD10 Homo sapiens Q9BWT7
Validated Y2H
32296183
Intra
CDC37 Q16543 CARD10 Homo sapiens Q9BWT7
Y2H Array
32296183
Intra
CDC37 Q16543 SRRM4 Homo sapiens A7MD48
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 SRRM4 Homo sapiens A7MD48
Y2H Array
32296183
Intra
CDC37 Q16543 ZBTB26 Homo sapiens Q9HCK0
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ZBTB26 Homo sapiens Q9HCK0
Validated Y2H
32296183
Intra
CDC37 Q16543 ZBTB26 Homo sapiens Q9HCK0
Y2H Array
32296183
Intra
CDC37 Q16543 KCTD9 Homo sapiens Q7L273
Y2H Array
32296183
Intra
CDC37 Q16543 KCTD9 Homo sapiens Q7L273
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 KCTD9 Homo sapiens Q7L273
Validated Y2H
32296183
Intra
CDC37 Q16543 CUL4B Homo sapiens Q13620
Lumier
25036637
Intra
CDC37 Q16543 FYN Homo sapiens P06241
Lumier
25036637
Intra
CDC37 Q16543 YES1 Homo sapiens P07947
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 YES1 Homo sapiens P07947
Lumier
25036637
Intra
CDC37 Q16543 TRAF5 Homo sapiens O00463
Y2H Array
32296183
Intra
CDC37 Q16543 TRAF5 Homo sapiens O00463
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 LRRK2 Homo sapiens Q5S007
Anti Tag CoIP
22612223
Intra
CDC37 Q16543 LRRK2 Homo sapiens Q5S007
Anti Tag CoIP
18367605
Intra
CDC37 Q16543 LRRK2 Homo sapiens Q5S007
TAP
16321986
Intra
CDC37 Q16543 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
CDC37 Q16543 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
CDC37 Q16543 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 SRC Homo sapiens P12931
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 AURKB Homo sapiens Q96GD4
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 AURKB Homo sapiens Q96GD4
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 ZNF655 Homo sapiens Q8N720
Validated Y2H
32296183
Intra
CDC37 Q16543 ZNF655 Homo sapiens Q8N720
Y2H Array
32296183
Intra
CDC37 Q16543 ZNF655 Homo sapiens Q8N720
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ERBB2 Homo sapiens P04626
Lumier
25036637
Intra
CDC37 Q16543 ERBB2 Homo sapiens P04626
TAP
24189400
Intra
CDC37 Q16543 MUSK Homo sapiens O15146
Lumier
25036637
Intra
CDC37 Q16543 AMHR2 Homo sapiens Q16671
Lumier
25036637
Intra
CDC37 Q16543 PSKH2 Homo sapiens Q96QS6
Lumier
25036637
Intra
CDC37 Q16543 ZNF843 Homo sapiens Q8N446
Lumier
22939624
Intra
CDC37 Q16543 ZNF843 Homo sapiens Q8N446
Lumier
25036637
Intra
CDC37 Q16543 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
CDC37 Q16543 PAICS Homo sapiens P22234
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PAICS Homo sapiens P22234
Y2H Array
32296183
Intra
CDC37 Q16543 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 STX1A Homo sapiens Q16623
Validated Y2H
32296183
Intra
CDC37 Q16543 STX1A Homo sapiens Q16623
Y2H Array
32296183
Intra
CDC37 Q16543 CUTC Homo sapiens Q9NTM9
Y2H Array
32296183
Intra
CDC37 Q16543 CUTC Homo sapiens Q9NTM9
Validated Y2H
32296183
Intra
CDC37 Q16543 CUTC Homo sapiens Q9NTM9
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 KATNBL1 Homo sapiens Q9H079
Y2H Array
32296183
Intra
CDC37 Q16543 KATNBL1 Homo sapiens Q9H079
Validated Y2H
32296183
Intra
CDC37 Q16543 KATNBL1 Homo sapiens Q9H079
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PPP5C Homo sapiens P53041
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 GRIPAP1 Homo sapiens Q4V328
Validated Y2H
32296183
Intra
CDC37 Q16543 GRIPAP1 Homo sapiens Q4V328
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 GRIPAP1 Homo sapiens Q4V328
Y2H Array
32296183
Intra
CDC37 Q16543 CGGBP1 Homo sapiens Q9UFW8
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CGGBP1 Homo sapiens Q9UFW8
Validated Y2H
32296183
Intra
CDC37 Q16543 CGGBP1 Homo sapiens Q9UFW8
Y2H Array
32296183
Intra
CDC37 Q16543 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
CDC37 Q16543 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
CDC37 Q16543 MRPL9 Homo sapiens Q9BYD2
Validated Y2H
32296183
Intra
CDC37 Q16543 SEPTIN3 Homo sapiens Q9UH03
Validated Y2H
32296183
Intra
CDC37 Q16543 SEPTIN3 Homo sapiens Q9UH03
Y2H Array
32296183
Intra
CDC37 Q16543 SEPTIN3 Homo sapiens Q9UH03
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
CDC37 Q16543 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
32296183
Intra
CDC37 Q16543 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra
CDC37 Q16543 USHBP1 Homo sapiens Q8N6Y0
Y2H Array
32296183
Intra
CDC37 Q16543 USHBP1 Homo sapiens Q8N6Y0
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ZBED1 Homo sapiens O96006
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ZBED1 Homo sapiens O96006
Y2H Array
32296183
Intra
CDC37 Q16543 THAP7 Homo sapiens Q9BT49
Validated Y2H
32296183
Intra
CDC37 Q16543 THAP7 Homo sapiens Q9BT49
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 THAP7 Homo sapiens Q9BT49
Y2H Array
32296183
Intra
CDC37 Q16543 THAP1 Homo sapiens Q9NVV9
Validated Y2H
32296183
Intra
CDC37 Q16543 THAP1 Homo sapiens Q9NVV9
Y2H Array
32296183
Intra
CDC37 Q16543 THAP1 Homo sapiens Q9NVV9
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 MAD1L1 Homo sapiens Q9Y6D9
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 MAD1L1 Homo sapiens Q9Y6D9
Validated Y2H
32296183
Intra
CDC37 Q16543 MAD1L1 Homo sapiens Q9Y6D9
Y2H Array
32296183
Intra
CDC37 Q16543 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
Intra
CDC37 Q16543 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ZBTB8A Homo sapiens Q96BR9
Validated Y2H
32296183
Intra
CDC37 Q16543 KCTD13 Homo sapiens Q8WZ19
Y2H Array
32296183
Intra
CDC37 Q16543 KCTD13 Homo sapiens Q8WZ19
Validated Y2H
32296183
Intra
CDC37 Q16543 KCTD13 Homo sapiens Q8WZ19
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 FATE1 Homo sapiens Q969F0
Validated Y2H
32296183
Intra
CDC37 Q16543 FATE1 Homo sapiens Q969F0
Y2H Array
32296183
Intra
CDC37 Q16543 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 GFAP Homo sapiens P14136
Y2H Array
32296183
Intra
CDC37 Q16543 GFAP Homo sapiens P14136
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 IFIT3 Homo sapiens O14879
Pull Down
21163940
Intra
CDC37 Q16543 IFIT3 Homo sapiens O14879
Y2H Array
21163940
Intra
CDC37 Q16543 IFIT3 Homo sapiens O14879
Anti Bait CoIP
21163940
Intra
CDC37 Q16543 AMOTL2 Homo sapiens Q9Y2J4
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 AMOTL2 Homo sapiens Q9Y2J4
Validated Y2H
32296183
Intra
CDC37 Q16543 AMOTL2 Homo sapiens Q9Y2J4
Y2H Array
32296183
Intra
CDC37 Q16543 KLHL2 Homo sapiens O95198
Y2H Array
32296183
Intra
CDC37 Q16543 KLHL2 Homo sapiens O95198
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
32296183
Intra
CDC37 Q16543 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra
CDC37 Q16543 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 CEP55 Homo sapiens Q53EZ4
Validated Y2H
32296183
Intra
CDC37 Q16543 CEP55 Homo sapiens Q53EZ4
Y2H Array
32296183
Intra
CDC37 Q16543 CEP55 Homo sapiens Q53EZ4
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 HOMER3 Homo sapiens Q9NSC5
Validated Y2H
32296183
Intra
CDC37 Q16543 HOMER3 Homo sapiens Q9NSC5
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 HOMER3 Homo sapiens Q9NSC5
Y2H Array
32296183
Intra
CDC37 Q16543 ZNF276 Homo sapiens Q8N554
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 ZNF276 Homo sapiens Q8N554
Validated Y2H
32296183
Intra
CDC37 Q16543 ZNF276 Homo sapiens Q8N554
Y2H Array
32296183
Intra
CDC37 Q16543 PRPH Homo sapiens P41219
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 PRPH Homo sapiens P41219
Y2H Array
32296183
Intra
CDC37 Q16543 SYCP3 Homo sapiens Q8IZU3
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 SYCP3 Homo sapiens Q8IZU3
Validated Y2H
32296183
Intra
CDC37 Q16543 SYCP3 Homo sapiens Q8IZU3
Y2H Array
32296183
Intra
CDC37 Q16543 CHUK Homo sapiens O15111
TAP
24189400
Intra
CDC37 Q16543 CHUK Homo sapiens O15111
TAP
14743216
Intra
CDC37 Q16543 CHUK Homo sapiens O15111
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 CHUK Homo sapiens O15111
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 IKBKB Homo sapiens O14920
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 IKBKB Homo sapiens O14920
TAP
14743216
Intra
CDC37 Q16543 IKBKB Homo sapiens O14920
Anti Tag CoIP
26496610
Intra
CDC37 Q16543 IKBKB Homo sapiens O14920
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 IKBKG Homo sapiens Q9Y6K9
Anti Tag CoIP
26496610
Intra
CDC37 Q16543 IKBKG Homo sapiens Q9Y6K9
TAP
14743216
Intra
CDC37 Q16543 IKBKG Homo sapiens Q9Y6K9
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 IKBKG Homo sapiens Q9Y6K9
Anti Tag CoIP
25036637
Intra
CDC37 Q16543 IKBKG Homo sapiens Q9Y6K9
TAP
24189400
Intra
CDC37 Q16543 TSSK6 Homo sapiens Q9BXA6
Lumier
25036637
Intra
CDC37 Q16543 FAM118A Homo sapiens Q9NWS6
Y2H Prey Pooling
32296183
Intra
CDC37 Q16543 FAM118A Homo sapiens Q9NWS6
Validated Y2H
32296183
Intra
CDC37 Q16543 FAM118A Homo sapiens Q9NWS6
Y2H Array
32296183
Intra
CDC37 Q16543 FBXW2 Homo sapiens Q9UKT8
Lumier
22939624
Intra
CDC37 Q16543 FBXW2 Homo sapiens Q9UKT8
Lumier
25036637
Intra
CDC37 Q16543 RPS6KA1 Homo sapiens Q15418
Anti Tag CoIP
33961781
Intra
CDC37 Q16543 RPS6KA1 Homo sapiens Q15418
TAP
24189400
Intra
CDC37 Q16543 CDK13 Homo sapiens Q14004
Lumier
25036637
Intra
CDC37 Q16543 STK38L Homo sapiens Q9Y2H1
Lumier
25036637
Cross
CDC37 Q16543 EIF2AK1 Oryctolagus cuniculus P33279
Pull Down
11036079
Cross
CDC37 Q16543 hsp90_rabit Oryctolagus cuniculus P11500
Anti Tag CoIP
11036079
Cross
CDC37 Q16543 hsp90_rabit Oryctolagus cuniculus P11500
Pull Down
11036079
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CDC37 Proteins

Cat. No. Product Name Accession Purity
HY-P75364 CDC37 Protein, Human (sf9, GST) Q16543 (M1-V378) ≥95%

Related Diseases

Diseases Alias
Macular Degeneration, Age-Related, 15

Age Related Macular Degeneration 15

ARMD15

Macular Degeneration, Age-Related, 15, Susceptibility To

Macular Degeneration, Age-Related, Type 15
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N1986 Cucurbitacin D 99.91% Unkown
HY-139301 DDO-5936 Inhibitor 99.20% Unkown
HY-144650 Hsp90-Cdc37-IN-3 98.09% Unkown
HY-N3417 Kongensin A ≥98.0% Unkown
HY-111414 Hsp90-Cdc37-IN-1 Inhibitor 99.66% Unkown
HY-119906 Conglobatin 95.48% Unkown
HY-130624 Hsp90-Cdc37-IN-2 / Unkown
HY-RS02297 CDC37 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02298 CDC37L1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CDC37 VGNC VGNC:38994
Rattus norvegicus CDC37 RGD RGD:71006
Bos taurus CDC37 VGNC VGNC:106679
Mus musculus CDC37 MGD MGI:109531
Macaca mulatta CDC37 VGNC VGNC:108494
Others CDC37 NCBI