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Isoforms Recommended: Bcl-2
Results for "

Bcl-2

" in MedChemExpress (MCE) Product Catalog:

302

Inhibitors & Agonists

1

Screening Libraries

15

Peptides

2

Inhibitory Antibodies

65

Natural
Products

17

Recombinant Proteins

7

Isotope-Labeled Compounds

18

Antibodies

27

Oligonucleotides

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Cat. No. Compare Product Name Species Source
  • HY-P72101
    BCL2 Protein, Mouse (His)
    1 Publications Verification

    Bcl2; Bcl-2; Apoptosis regulator Bcl-2

    		 Mouse E. coli
    BCL2 protein crucially regulates cell death by controlling mitochondrial membrane permeability. It interacts with caspases in a feedback loop, inhibiting their activity. BCL2 prevents cytochrome c release from mitochondria and binds to apoptosis-activating factor (APAF-1). BCL2 Protein, Mouse (His) is the recombinant mouse-derived BCL2 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P7537
    BCL2 Protein, Human (His)

    rHuApoptosis Regulator Bcl-2, His; B-cell Lymphoma 2; Apoptosis Regulator Bcl-2

    		 Human E. coli
    BCL2 Protein, Human (His) expresses in E. coli with a His tag at the N-terminus. Proteins of the Bcl-2 family are important regulators of apoptosis in many tissues of the embryo and adult.
  • HY-P75590
    BCL2A1 Protein, Human (His)

    Bcl-2-related protein A1; Protein BFL-1; Bcl2L5; BFL1; GRS; HBPA1

    		 Human E. coli
    The BCL2A1 protein plays a critical role in resisting apoptosis triggered by IL-3 deprivation, suggesting its importance in the response of hematopoietic cells to external signals and may be involved in protecting endothelial cell survival during infection. It also inhibits serum starvation-induced apoptosis in mammary epithelial cells (HC11). BCL2A1 Protein, Human (His) is the recombinant human-derived BCL2A1 protein, expressed by E. coli , with N-His labeled tag. The total length of BCL2A1 Protein, Human (His) is 152 a.a., with molecular weight of 16-17 kDa.
  • HY-P7650
    Bcl-2-like protein 1 Protein, Human (His)

    rHuBcl-2-like protein 1, His; Bcl-2-Like Protein 1; Apoptosis Regulator Bcl-X; Bcl2L

    		 Human E. coli
    Bcl-2-like protein 1 Protein, Human (His) is an important apoptosis regulating gene that codes for both an anti-apoptotic (Bcl-xL) and a pro-apoptotic (Bcl-xS) splice variant.
  • HY-P7653
    Bcl-2-like protein 2 Protein, Human (His)

    rHuBcl-2-like protein 2, His; Bcl-2-Like Protein 2; Apoptosis Regulator Bcl-W; Bcl2L2; KIAA0271

    		 Human E. coli
    Bcl-2-like protein 2 is a key regulator that promotes cell survival and prevents dexamethasone-induced apoptosis, which is critical for postmitotic Sertoli cells. It inhibits BAX, emphasizing its role in survival mechanisms. Bcl-2-like protein 2 Protein, Human (His) is the recombinant human-derived Bcl-2-like protein 2 protein, expressed by E. coli , with C-6*His labeled tag. The total length of Bcl-2-like protein 2 Protein, Human (His) is 171 a.a., with molecular weight of ~18.0 kDa.
  • HY-P700303
    Bcl-2-like Protein 11 Protein, Human (His)

    rHuBcl-2-like Protein 11, His; Bcl-2-like protein 11; BIML

    		 Human E. coli
    Bcl-2-like protein 11 (BCL2L11), despite its classification, does not interact with humanin. This unique feature distinguishes BCL2L11 from expected protein-protein interactions typically associated with Bcl-2 family members. Bcl-2-like Protein 11 Protein, Human (His) is the recombinant human-derived Bcl-2-like Protein 11 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P72846
    Bcl-XL Protein, Mouse (His)

    Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X; Bclx

    		 Mouse E. coli
    Bcl-XL protein forms heterodimers with BAX, BAK, or BCL2, but its antiapoptotic activity does not require heterodimerization with BAX. Bcl-XL Protein, Mouse (His) is the recombinant mouse-derived Bcl-XL protein, expressed by E. coli , with C-His labeled tag. The total length of Bcl-XL Protein, Mouse (His) is 212 a.a., with molecular weight of ~33 kDa.
  • HY-P72846A
    Bcl-XL Protein, Mouse (C-His)

    Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X; Bclx

    		 Mouse E. coli
    Bcl-XL protein forms heterodimers with BAX, BAK, or BCL2, but its antiapoptotic activity does not require heterodimerization with BAX. Bcl-XL Protein, Mouse (C-His) is the recombinant mouse-derived Bcl-XL, expressed by E. coli , with C-6*His labeled tag. The total length of Bcl-XL Protein, Mouse (C-His) is 212 a.a.,
  • HY-P76165
    BCL2L12 Protein, Human (GST)

    Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein; BPR

    		 Human E. coli
    BCL2-like 12 (BCL2L12) is a new member of the apoptosis-related BCL2 gene family. BCL2L12 contains a highly conserved BH2 domain, a BH3-like domain and a proline-rich region. BCL2L12 exhibits pro-apoptotic activity in breast tumor and gastric cancer. BCL2L12 is an inhibitor of post-mitochondrial effector caspase activation, as it binds to and inhibits caspase-7 and upregulates the caspase-3-specific inhibitor 伪B-crystallin (CRYAB). BCL2L12 attenuates endogenous p53-directed transcriptomic changes after genotoxic stress and inhibits p53-dependent DNA damage-induced apoptosis. BCL2L12 Protein, Human (GST) is the recombinant human-derived BCL2L12 protein, expressed by E. coli , with N-GST labeled tag.
  • HY-P75473
    BMF Protein, Human (His)

    Bcl-2-modifying factor; BMF

    		 Human E. coli
    BMF proteins may play a key role in apoptosis, with isoform 1 being the major promoter. It interacts with anti-apoptotic proteins (including MCL1, BCL2, BCL2L1/BCL-Xl, BCL2A1 and BCL2L2/BCL-w), suggesting involvement in the regulatory network of cell death. BMF Protein, Human (His) is the recombinant human-derived BMF protein, expressed by E. coli , with N-His labeled tag.
  • HY-P703089
    BAK1 Protein, Human

    BAK; Bcl2L7; CDN1

    		 Human E. coli
    BAK1 Protein, Human is the recombinant human-derived BAK1, expressed by E. coli , with tag Free labeled tag. The total length of BAK1 Protein, Human is 185 a.a.,
  • HY-P702614
    Bax Protein, Human (Cell-Free, His)

    rHuBcl2L4, His; Apoptosis Regulator BAX; Bcl-2-Like Protein 4; Bcl2L4; BAX

    		 Human E. coli Cell-free
    Bax Protein, Human (Cell-Free, His) is the recombinant human-derived Bax, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of Bax Protein, Human (Cell-Free, His) is 192 a.a.,
  • HY-P702954
    BAD Protein, Human (sf9, GST)

    BBC6; Bcl2L8

    		 Human Sf9 insect cells
    BAD Protein, Human (sf9, GST) is the recombinant human-derived BAD, expressed by Sf9 insect cells , with GST labeled tag. The total length of BAD Protein, Human (sf9, GST) is 168 a.a.,
  • HY-P71848
    BAG-3 Protein, Mouse (P.pastoris, His)

    Bag3; Bis; MNCb-2243BAG family molecular chaperone regulator 3; BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis

    		 Mouse P. pastoris
    The BAG-3 protein is a co-chaperone of HSP70 and HSC70, acting as a nucleotide exchange factor to promote the release of ADP from these partners, thus triggering substrate release. BAG-3 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived BAG-3 protein, expressed by P. pastoris , with N-His labeled tag. The total length of BAG-3 Protein, Mouse (P.pastoris, His) is 576 a.a., with molecular weight of ~63.7 kDa.
  • HY-P7647
    BAG-2 Protein, Human (His)

    rHuBAG2, His; BAG Family Molecular Chaperone Regulator 2; BAG-2; Bcl-2-Associated Athanogene 2; BAG2

    		 Human E. coli
    BAG2 Protein, Human (His) promotes tumorigenesis through enhancing mutant p53 protein levels and function. BAG2 is a target of the c-Myc gene and is involved in cellular senescence via the p21CIP1 pathway.
  • HY-P7670
    BNIP3/NIP3 Protein, Human (His)

    rHuBNIP3, His; BNIP3; NIP3; Bcl2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3

    		 Human E. coli
    BNIP3/NIP3 Protein, Human (His) expresses in E. coliwith a His tag. BNIP3 belongs to the Bcl-2 protein family that regulates programmed cell death.
  • HY-P75471
    BNIP3L Protein, Human

    Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3-like; NIP3L; BNIP3L; BNIP3A; BNIP3H; NIX

    		 Human E. coli
    BNIP3L, a pro-apoptotic member of the Bcl-2 family, possesses a BH3 domain and binds to Bcl-2. It directly targets mitochondria, inducing apoptotic changes like membrane potential loss and cytochrome c release. With ubiquitous expression, especially in fat and ovary, the gene suggests involvement in diverse physiological processes across multiple organs, emphasizing its potential significance. BNIP3L Protein, Human is the recombinant human-derived BNIP3L protein, expressed by E. coli , with tag free. The total length of BNIP3L Protein, Human is 186 a.a., with molecular weight of ~32-36 kDa.

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