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Results for "

fluorogenic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Amino Acid Derivatives (2) Aminopeptidase (1) Angiotensin Receptor (2) Angiotensin-converting Enzyme (ACE) (3) Apoptosis (1) Bacterial (2) Biochemical Assay Reagents (9) Caspase (13) Cathepsin (6) Cholinesterase (ChE) (4) CRISPR/Cas9 (1) Cytochrome P450 (3) DNA Stain (1) EGFR (1) Endogenous Metabolite (1) Endothelin Receptor (1) Factor Xa (1) Fluorescent Dye (120) Furin (1) Glycosidase (1) HIV (1) HIV Protease (1) MAGL (1) MMP (6) Parasite (1) Phosphatase (3) Phospholipase (3) Protease Activated Receptor (PAR) (1) Proteasome (8) Reactive Oxygen Species (1) SARS-CoV (1) Ser/Thr Protease (5) Sirtuin (2) Virus Protease (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (4) Endocrinology (1) Infection (4) Inflammation/Immunology (9) Metabolic Disease (9) Neurological Disease (5)
Click Chemistry:	Labeling and Fluorescence Imaging (2) Azide (7)

202

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

115

Peptides

Natural
Products

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-134961

Z-Ala-Arg-Arg-AMC fluorogenic Proteasome Substrate; Z-ARR-AMC	Proteasome	Others
Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome .

HY-155002

*hCYP3A4 Fluorogenic* substrate 1**	Cytochrome P450	Metabolic Disease
hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an K_m value of 0.36 μM. hCYP3A4 Fluorogenic substrate 1 can be used for cell and in vivo imaging .

HY-P10189

α-Secretase Substrate, Fluorogenic	Biochemical Assay Reagents	Others
α-Secretase Substrate, Fluorogenic is α-secretase fluorogenic substrate that can be used to test α-secretase activity .

HY-P2179

MMP-1/MMP-9 Substrate, Fluorogenic	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm

HY-P10163

α-Secretase Substrate II, Fluorogenic	Fluorescent Dye	Others
α-Secretase Substrate II, Fluorogenic is an internally quenched fluorogenic peptide substrate for α-Secretase that contains the α-secretase cleavage site of β-Amyloid precursor protein (APP) .Ex/Em = 340/490 nm

HY-D2284

*SGPL1 fluorogenic* substrate** Sphingosine-1-phosphate lyase fluorogenic substrate	Fluorescent Dye	Cancer
SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .

HY-P10008

Cathepsin D/E Substrate, Fluorogenic	Cathepsin	Cancer
Cathepsin D/E Substrate, Fluorogenic, 11 amino acid peptide, is a selective substrate for cathepsins D and E. Cathepsin D/E Substrate, Fluorogenic does not act as a substrate for cathepsins B, H, or L .

HY-P2682

*MMP-8/MMP-26 Fluorogenic* substrate**	MMP	Metabolic Disease
MMP-8/MMP-26 Fluorogenic substrate (DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg) is a matrix metalloproteinase-8 (MMP-8) fluorogenic substrate. MMP-8/MMP-26 Fluorogenic substrate can be used for the research of atherosclerosis, pulmonary fibrosis, and sepsis .

HY-P10073

Calpain-1 substrate, fluorogenic	Fluorescent Dye	Others
Calpain-1 substrate, fluorogenic serves as a sensitive and specific substrate for calpain-1 that cleaves Tyr-Gly bond and results in enhanced fluorescence .(Ex/Em = 490 nm/518 nm)

HY-P4366

Tos-Gly-Pro-Lys-AMC	Ser/Thr Protease	Others
Tos-Gly-Pro-Lys-AMC is a fluorogenic peptide substrate of tryptase .

HY-W719799

Suc-Ala-Leu-Pro-Phe-AMC	Fluorescent Dye	Others
Suc-Ala-Leu-Pro-Phe-AMC is a PPIase fluorogenic substrate .

HY-116583

Resorufin butyrate	Cholinesterase (ChE)	Metabolic Disease
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm) .

HY-D2287

CalFluor 555 azide	Fluorescent Dye	Others
CalFluor 555 azide is a fluorogenic azide probe. CalFluor 555 azide is not fluorescent until it is reacted with alkynes (Ex=555 nm) .

HY-D2287A

CalFluor 555 azide chloride	Fluorescent Dye	Others
CalFluor 555 azide (chloride) is a fluorogenic azide probe. CalFluor 555 azide (chloride) is not fluorescent until it is reacted with alkynes (Ex=555 nm) .

HY-P5993

MeOSuc-Ala-Ala-Pro-Val-4-MNA	Fluorescent Dye	Others
MeOSuc-Ala-Ala-Pro-Val-4-MNA is a elastase fluorogenic substrate that can be detected at 425 nm (with excitation at 340 nm) .

HY-W286423

L-Pyroglutamic acid 7-amido-4-methylcoumarin	Fluorescent Dye Aminopeptidase	Inflammation/Immunology
L-Pyroglutamic acid 7-amido-4-methylcoumarin is a fluorogenic substrate for pyroglutamate aminopeptidase 1 (PGP-1) .

HY-D0063

6,7-Diethoxy-4-methylcoumarin	Fluorescent Dye	Others
6,7-Diethoxy-4-methylcoumarin is a fluorogenic substrate and is also a metabolite of Cordyceps militaris .

HY-137928

H-Ala-4MβNA hydrochloride	Fluorescent Dye	Others
H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M .

HY-P4334

Bz-RGFFL-4MβNA Bz-Arg-Gly-Phe-Phe-Leu-4MβNA	Fluorescent Dye	Others
Bz-RGFFL-4MβNA (Bz-Arg-Gly-Phe-Phe-Leu-4MβNA) is a peptide and can be used fluorogenic substrate .

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	MMP	Cancer
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) .

HY-123052

Ac-PAL-AMC	Proteasome	Inflammation/Immunology
Ac-PAL-AMC is a fluorogenic substrate specific for 20S proteasome LMP2/β1i activity .

HY-P3699

TNO003	Fluorescent Dye	Others
TNO003 is a selective fluorogenic substrate. TNO003 can be used for the research of various biochemical .

HY-134432A

Boc-Gln-Ala-Arg-AMC hydrochloride	Ser/Thr Protease	Others
Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-134432B

Boc-Gln-Ala-Arg-AMC acetate	Ser/Thr Protease	Others
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-155667A

Z-Nle-Lys-Arg-AMC acetate	Cathepsin	Others
Z-Nle-Lys-Arg-AMC acetate is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .

HY-P3475

Mca-VDQMDGW-K(Dnp)-NH2	Fluorescent Dye	Others
Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .

HY-P2617

Ac-WEHD-AFC	Caspase	Inflammation/Immunology Cancer
Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .

HY-D1705

Ac-ANW-AMC	Proteasome	Inflammation/Immunology
Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .

HY-P2617A

Ac-WEHD-AFC TFA	Caspase	Inflammation/Immunology Cancer
Ac-WEHD-AFC TFA is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC TFA can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .

HY-P4427

Z-VAN-AMC	Fluorescent Dye	Others
Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity .

HY-123051

Ac-WLA-AMC	Proteasome	Inflammation/Immunology
Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate .

HY-D0994

4-Methylumbelliferyl phosphate 4-MUP; MUP	Phosphatase	Others
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

HY-134435

Z-Arg-AMC hydrochloride	Fluorescent Dye	Others
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .

HY-D1689

Rf470DL	Bacterial	Infection
Rf470DL is a rotor-fluorogenic D-amino acid (RfDAA). Rf470DL can be used for labeling bacteria (Ex=470 nm, Em=640 nm) .

HY-155667

Z-Nle-Lys-Arg-AMC	Others	Others
Z-Nle-Lys-Arg-AMC is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .

HY-119791

NBD-amine	Fluorescent Dye	Others
NBD-amine is a fluorogenic amine. NBD-amine displays the property of fluorescing weakly in water and strongly in organic solvents, membranes or hydrophobic environments .

HY-P3477

Mca-PLA-Nva-Dap(Dnp)-AR-NH2	Fluorescent Dye	Others
Mca-PLA-Nva-Dap(Dnp)-AR-NH2 is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) .

HY-136865

MeOSuc-AAPV-AMC	Fluorescent Dye	Others
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (K_m: 362 μM, Ex=380 nm, Em=460 nm) .

HY-P5996

MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2	Fluorescent Dye	Others
MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2 is a protein tyrosine phosphatase fluorogenic substrate that can be detected at 393 nm (with excitation at 325 nm) .

HY-D1386

JF526-Taxol TFA	Fluorescent Dye	Others
JF526-Taxol (TFA) is a versatile scaffold for fluorogenic probes including ligands for self-labeling tags, stains for endogenous structures, and spontaneously blinking labels for super-resolution immunofluorescence .

HY-P2620

Ac-LETD-AFC	Fluorescent Dye	Metabolic Disease Cancer
Ac-LETD-AFC is a *caspase-8 fluorogenic* substrate*. Ac-LETD-AFC can measure caspase-8 fluorogenic* activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism .

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Caspase	Others
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-P3362

Ac-IETD-AMC	Fluorescent Dye	Others
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

HY-D1252

Fast-TRFS 2 Publications Verification	Fluorescent Dye	Others
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells .

HY-W357142

3-Acetylumbelliferyl β-D-Glucopyranoside	Fluorescent Dye	Metabolic Disease Inflammation/Immunology
3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase .

HY-P2498

Cathepsin D and E FRET Substrate	Cathepsin	Others
Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .

HY-P2498A

Cathepsin D and E FRET Substrate acetate	Cathepsin	Cancer
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .

HY-120166

DiFMUP 1 Publications Verification 6,8-Difluoro-4-methylumbelliferyl phosphate	Phosphatase	Others
DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader .

HY-W354821

4-Methylumbelliferyl Decanoate 4-MUD	Fluorescent Dye	Metabolic Disease
4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases .

HY-W275616

4-Methylumbelliferyl nonanoate	Others	Others
4-Methylumbelliferyl nonanoate is a fluorogenic substrate of esterases. 4-Methylumbelliferyl nonanoate can be hydrolyzed to 4-methylumbelliferone with bright blue fluorescence .

Cat. No.	Product Name	Type

HY-D0719

Fluorescein Diacetate 4 Publications Verification 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein	Dyes Enzyme Substrates
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-W286423

L-Pyroglutamic acid 7-amido-4-methylcoumarin	Enzyme Substrates
L-Pyroglutamic acid 7-amido-4-methylcoumarin is a fluorogenic substrate for pyroglutamate aminopeptidase 1 (PGP-1) .

HY-137164

Ala-Ala-Phe-AMC	Biochemical Assay Reagents
Ala-Ala-Phe-AMC serves as a fluorogenic substrate that exhibits positively charged properties, making it suitable for assessing proteolytic activity.

HY-D0719R

Fluorescein Diacetate (Standard)	Dyes Enzyme Substrates
Fluorescein Diacetate (Standard) is the analytical standard of Fluorescein Diacetate. This product is intended for research and analytical applications. Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-D0935

4-Methylumbelliferyl-β-D-glucuronide	Biochemical Assay Reagents
4-Methylumbelliferyl-β-D-glucuronide is a fluorogenic substrat (λ_ex=362 nm, λ_em=445 nm). 4-Methylumbelliferyl-β-D-glucuronide has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .

HY-W776853

4-Methylumbelliferyl β-D-N,N',N'',N'''-tetraacetylchitotetraoside

Enzyme Substrates

4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside is a fluorogenic substrate with activity for lysozyme assays. 4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside can be used to study enzyme activity and its applications in biomedicine. 4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside exhibits high sensitivity in analyzing enzyme reactions in biological samples.

HY-123000

4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside

Enzyme Substrates

4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is a fluorogenic substrate for studying the enzymatic activity of α-galactosidase. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is used to analyze enzyme activity in various biological samples, helping scientists gain insight into the function of the enzyme in vivo. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside can also be used to screen potential compounds to inhibit or activate this enzyme.

Cat. No.	Product Name		Classification

HY-131027

*Janelia Fluor® 646, Azide* JF646, Azide		Azide Labeling and Fluorescence Imaging
Janelia Fluor 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor 646, Azide can be used for live-cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D2287

CalFluor 555 azide		Azide
CalFluor 555 azide is a fluorogenic azide probe. CalFluor 555 azide is not fluorescent until it is reacted with alkynes (Ex=555 nm) .

HY-D2287A

CalFluor 555 azide chloride		Azide
CalFluor 555 azide (chloride) is a fluorogenic azide probe. CalFluor 555 azide (chloride) is not fluorescent until it is reacted with alkynes (Ex=555 nm) .

HY-D2288

CalFluor 580 azide		Azide
CalFluor 580 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 580 azide is not fluorescent until it is reacted with alkynes .

HY-D2289

CalFluor 647 azide		Azide
CalFluor 647 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 647 azide is not fluorescent until it is reacted with alkynes .

HY-151708

CalFluor 488 Azide		Azide
CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151710

Sulfo-Cy3 Azide		Labeling and Fluorescence Imaging Azide
Sulfo-Cy3 Azide is a water-soluble fluorogenic dye containing an azide group, which enables Click Chemistry. Sulfo-Cy3 Azide can be used for the labeling of sensitive molecules such as proteins . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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