Search Result

Results for "

peptidase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Dipeptidyl Peptidase (70) Amino Acid Derivatives (1) Aminopeptidase (3) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (6) Apoptosis (9) Autophagy (1) Bacterial (11) Biochemical Assay Reagents (10) Carbonic Anhydrase (1) Cathepsin (1) ClpP (1) Deubiquitinase (7) DNA Alkylator/Crosslinker (1) Elastase (2) Endogenous Metabolite (1) Ferroptosis (5) Fluorescent Dye (4) FXR (1) GCGR (2) GLP Receptor (1) Glucosidase (2) Glutathione Peroxidase (2) GPR119 (2) HIV (1) Insulin Receptor (2) Interleukin Related (2) Isotope-Labeled Compounds (4) mGluR (2) Mitophagy (1) MMP (5) Neuropeptide Y Receptor (1) NOD-like Receptor (NLR) (1) Nuclear Hormone Receptor 4A/NR4A (1) Opioid Receptor (1) P-glycoprotein (1) Phospholipase (1) Potassium Channel (1) Proteasome (1) Reactive Oxygen Species (1) Ser/Thr Protease (4) TNF Receptor (2) γ-secretase (1)
By Research Areas:	Cancer (24) Cardiovascular Disease (7) Endocrinology (3) Infection (13) Inflammation/Immunology (18) Metabolic Disease (63) Neurological Disease (9)

By Targets:

Dipeptidyl Peptidase (70)

Amino Acid Derivatives (1)

Aminopeptidase (3)

Angiotensin-converting Enzyme (ACE) (1)

Antibiotic (6)

Apoptosis (9)

Autophagy (1)

Bacterial (11)

Biochemical Assay Reagents (10)

Carbonic Anhydrase (1)

Cathepsin (1)

ClpP (1)

Deubiquitinase (7)

DNA Alkylator/Crosslinker (1)

Elastase (2)

Endogenous Metabolite (1)

Ferroptosis (5)

Fluorescent Dye (4)

FXR (1)

GCGR (2)

GLP Receptor (1)

Glucosidase (2)

Glutathione Peroxidase (2)

GPR119 (2)

HIV (1)

Insulin Receptor (2)

Interleukin Related (2)

Isotope-Labeled Compounds (4)

mGluR (2)

Mitophagy (1)

MMP (5)

Neuropeptide Y Receptor (1)

NOD-like Receptor (NLR) (1)

Nuclear Hormone Receptor 4A/NR4A (1)

Opioid Receptor (1)

P-glycoprotein (1)

Phospholipase (1)

Potassium Channel (1)

Proteasome (1)

Reactive Oxygen Species (1)

Ser/Thr Protease (4)

TNF Receptor (2)

γ-secretase (1)

By Research Areas:

Cancer (24)

Cardiovascular Disease (7)

Endocrinology (3)

Infection (13)

Inflammation/Immunology (18)

Metabolic Disease (63)

Neurological Disease (9)

153

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Dipeptidyl Peptidase Kallikrein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-E70017

Peptidase, microorganism Erepsin; peptidase (IMPa)	Others	Others
Peptidase (IMPa) (Erepsin) is catalytically active enzyme that cleaves peptide bonds in proteins and peptides by hydrolysis .

HY-E70397

*Dipeptidyl peptidase* IV** DPP-IV	Others	Metabolic Disease Cancer
Dipeptidyl peptidase IV (DPP-IV) is a protease that inactivates insulin stimulating hormones such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulin-like polypeptide (GIP). Dipeptidyl peptidase IV can be used as a binding protein and ligand for various extracellular molecules. Dipeptidyl peptidase IV can be used in diabetes research .

HY-P4470

Phe-Pro-Ala-pNA	Ser/Thr Protease	Cancer
Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .

HY-E70432

*Dipeptidyl peptidase* VII (human)**	Biochemical Assay Reagents	Others
Dipeptidyl peptidase VII (human) is a peptidase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-P4464

Ala-Phe-Pro-pNA	Ser/Thr Protease	Cancer
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .

HY-W764737

Methylboronic acid pinacol ester-d3	Isotope-Labeled Compounds	Cancer
Methylboronic acid pinacol ester is an orally administered compound that inhibits the activity of peptidases and imidazole derivatives. Methylboronic acid pinacol ester is used as a medicinal preparation for cancer .

HY-E70427

*Dipeptidyl peptidase* IX (human)**	Biochemical Assay Reagents	Others
Dipeptidyl peptidase IX (human) is a hydrolase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-E70434

*Dipeptidyl peptidase* III (human)**	Biochemical Assay Reagents	Others
Dipeptidyl peptidase III (human) is a hydrolase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-137199

Pro-Phe-Arg-AMC	Biochemical Assay Reagents	Others
Pro-Phe-Arg-AMC is a synthetic peptide substrate of Cysteine peptidases (CPs) .

HY-137164A

Ala-Ala-Phe-AMC TFA	Fluorescent Dye	Others
Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination .

HY-W010955

Z-Phe-Leu-OH NSC 334018	Biochemical Assay Reagents	Others
Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity .

HY-E70005A

Collagenase, Type I 2 Publications Verification EC 3.4.24.3	MMP	Others
Collagenase, Type I is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type I breaks down collagens 1, 3, 7, 8, 10, gelatin, proteoglycans, aggrecan .

HY-E70005B

Collagenase, Type II 2 Publications Verification	MMP	Others
Collagenase, Type II is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type II breaksdown collagens1, 3, 5, 7, 8, 10, fibronectin, gelatin, aggrecann .

HY-E70005E

Collagenase, Type V	MMP	Others
Collagenase, Type V is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type V breaksdown collagens1, 3, 5, 7, 8, 10, fibronectin, gelatin, aggrecann .

HY-E70005C

Collagenase, Type III	MMP	Others
Collagenase, Type III is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type III breaksdown collagens1, 4, 9, 10, 14, fibronectin, MMP-9, gelatin, plasminogen, aggrecan,perlecan osteonectin

HY-14293

NVP-DPP728 dihydrochloride	Dipeptidyl Peptidase	Metabolic Disease
NVP-DPP728 dihydrochloride is a potent, selective and orally active dipeptidyl peptidase IV (DPP-IV) inhibitor with a K_i of 11 nM. NVP-DPP728 dihydrochloride can be used for the research of diabetes mellitus .

HY-137870

γ-Glutamyl-β-naphthylamide gamma-Glutamyl-beta-naphthylamide	Biochemical Assay Reagents	Others
γ-Glutamyl-β-naphthylamide is a substrate for γ-glutamine peptidase. γ-Glutamyl-β-naphthylamide is specifically recognized and the peptide chain is cleaved. γ-Glutamyl-β-naphthylamide can be used to distinguish between gonococci and meningococci .

HY-E70005D

Collagenase IV, Clostridium histolytica Collagenase, Type IV	MMP	Others
Collagenase, Type IV (EC 3.4.24.3) is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type IV degrades type IV collagen and type VII collagen, the main components of the basement membrane, and can also decompose basement matrix and elastin.

HY-14291

Vildagliptin 4 Publications Verification LAF237; NVP-LAF 237	Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease Cancer
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-14291A

Vildagliptin dihydrate LAF237 dihydrate; NVP-LAF 237 dihydrate	Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease Cancer
Vildagliptin dihydrate (LAF237 dihydrate) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin dihydrate possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-150070

Butabindide UCL-1397	Others	Neurological Disease
Butabindide (UCL-1397) is a potent, selective *tripeptidvl peptidase* II (TPP II) inhibitor with K_i** values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide inhibits TPP II to protect CCK-8 against inactivation .

HY-14291R

Vildagliptin (Standard)	Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease
Vildagliptin (Standard) is the analytical standard of Vildagliptin. This product is intended for research and analytical applications. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-107759

Butabindide oxalate UCL-1397 oxalate	Others	Neurological Disease
Butabindide (UCL-1397) oxalate is a potent, selective *tripeptidvl peptidase* II (TPP II) inhibitor with K_i** values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide oxalate inhibits TPP II to protect CCK-8 against inactivation .

HY-14291B

(2R)-Vildagliptin (2R)-LAF237; (2R)-NVP-LAF 237	Others	Metabolic Disease
(2R)-Vildagliptin is the isomer of Vildagliptin (HY-14291), and can be used as an experimental control. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-D2327

DPP-8/9 probe-1	Dipeptidyl Peptidase	Others
DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC₅₀ of 210 nM and 15 nM, respectively) .

HY-18522

AA26-9	Phospholipase	Metabolic Disease
AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. AA26-9 shows inhibitory activity against approximately 1/3 of the 40+ serine hydrolases detected in immortalized T cell lines .

HY-129736A

P32/98	Dipeptidyl Peptidase	Metabolic Disease
P32/98 a potent inhibitor of *dipeptidyl peptidase* IV** with a K_i value of 130 nM. P32/98 improves glucose tolerance, insulin sensitivity and β-cell responsiveness in fatty Zucker rat model .

HY-14291S2

Vildagliptin-13C5,15N LAF237-¹³C₅,¹⁵N; NVP-LAF 237-¹³C₅,¹⁵N	Isotope-Labeled Compounds	Metabolic Disease
Vildagliptin- ¹³C₅, ¹⁵N (LAF237- ¹³C₅, ¹⁵N; NVP-LAF 237- ¹³C₅, ¹⁵N) is a ¹³C- and ¹⁵N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-129736

P32/98 hemifumarate	Dipeptidyl Peptidase	Metabolic Disease
P32/98 hemifumarateis a potent inhibitor of *dipeptidyl peptidase* IV** with a K_i value of 130 nM. P32/98 hemifumarate improves glucose tolerance, insulin sensitivity and β-cell responsiveness in fatty Zucker rat model .

HY-P4920

Mca-SEVNLDAEFK(Dnp)-NH2	Fluorescent Dye	Others
Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 .

HY-14292

NVP-DPP728	Dipeptidyl Peptidase	Metabolic Disease
NVP-DPP728 is a potent, reversible and nitrile-dependent *dipeptidyl peptidase* IV (DPP-IV) inhibitor. NVP-DPP728 can inhibit human DPP-IV amidolytic activity with a K_i** of 11 nM. NVP-DPP728 inhibits degradation of glucagon-like peptide-1 (GLP-1) and thereby potentiates insulin release in response to glucose intake. NVP-DPP728 can be used for researching diabetes .

HY-129407

AAF-CMK TFA Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl peptidase inhibitor II	Others	Infection
AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.

HY-10289

Carmegliptin RO-4876904	Dipeptidyl Peptidase P-glycoprotein	Cardiovascular Disease Metabolic Disease
Carmegliptin (RO-4876904) is an orally active, potent and long-acting *dipeptidyl peptidase* IV inhibitor. Carmegliptin is also a substrate of P-glycoprotein** that synergizes with Verapamil (HY-14275). Carmegliptin improves insulin sensitivity and reduces hepatic glucose production in hyperglycemic mice. Carmegliptin is promising for research of type 2 diabetes, hypertension and cardiovascular disease .

HY-P4460

AAA-pNA	Ser/Thr Protease	Cancer
AAA-pNA is a chromogenic substrate of *Tripeptidyl-peptidase* II*. AAA-pNA can be used to test Tripeptidyl-peptidase* II activity .

HY-151871

ICeD-2	Dipeptidyl Peptidase HIV	Infection
ICeD-2 is a inducer of cell death, can induce HIV-1 infected cell kill. ICeD-2-mediated HIV-1 infected cell kill is dependent on HIV-1 protease activity. ICeD-2 potently blocks hydrolysis of Gly-Pro-AMC by *dipeptidyl peptidase* DPP8 and DPP9**. ICeD-2 shows strong stabilization of DPP9 in PBMCs .

HY-P2543

Neuropeptide Y (3-36) (human, rat)	Neuropeptide Y Receptor	Metabolic Disease
Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor .

HY-10286A

Dutogliptin tartrate PHX-1149	Dipeptidyl Peptidase	Metabolic Disease
Dutogliptin tartrate (PHX-1149) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.

HY-10286

Dutogliptin PHX-1149 free base	Dipeptidyl Peptidase	Metabolic Disease
Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.

HY-N10362

Ellipyrone B	Dipeptidyl Peptidase	Metabolic Disease
Ellipyrone B, an antihyperglycemic γ-pyrone enclosed macrocyclic polyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC₅₀=0.48 mM) .

HY-112668

Retagliptin phosphate 1 Publications Verification SP2086 phosphate	Dipeptidyl Peptidase	Metabolic Disease
Retagliptin phosphate (SP2086 phosphate) is a selective, competitive and orally active *dipeptidyl peptidase-4 (DPP-4)* inhibitor. Retagliptin phosphate can be used for type 2 diabetes mellitus (T2DM) research .

HY-112668A

Retagliptin 1 Publications Verification SP2086	Dipeptidyl Peptidase	Metabolic Disease
Retagliptin (SP2086) is a selective, competitive and orally active *dipeptidyl peptidase-4 (DPP-4)* inhibitor. Retagliptin can be used for type 2 diabetes mellitus (T2DM) research .

HY-P2233

Globomycin	Bacterial Antibiotic	Infection
Globomycin is a lipopeptide antibiotic and a *signal peptidase* II (LspA)** inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute *Spiroplasma melliferum* with a MIC in the range 6.25-12.5 μM .

HY-10287

Gosogliptin 1 Publications Verification PF-00734200; PF-734200	Dipeptidyl Peptidase	Metabolic Disease
Gosogliptin is a potent and selective inhibitor of dipeptidyl peptidase-IV (DPP-IV).

HY-139440

DL-Leucyl-DL-phenylalanine	Others	Others
DL-Leucyl-DL-phenylalanine is a dipeptide and can be used as a substrate to detecte two regions of dipeptidase staining on a gel in Drosophila simulans as well as in Drosophila melanogaster .

HY-10285

Saxagliptin 5 Publications Verification BMS-477118	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active *dipeptidyl peptidase-4 (DPP-4)* (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-10285A

Saxagliptin hydrate 5 Publications Verification BMS-477118 hydrate	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active *dipeptidyl peptidase-4 (DPP-4)* (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research .

HY-16448

Saxagliptin hydrochloride 5 Publications Verification BMS-477118 hydrochloride	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active *dipeptidyl peptidase-4 (DPP-4)* (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research .

HY-111174

Diprotin A Ile-Pro-Ile	Dipeptidyl Peptidase	Metabolic Disease
Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV) .

HY-163335

MPO-IN-7	Glutathione Peroxidase Dipeptidyl Peptidase Glucosidase	Cardiovascular Disease Inflammation/Immunology
MPO-IN-7 (compound MDC) is a myeloperoxidase inhibitor with the IC₅₀ values of 41 μM, 25 μM and 4.5 μM towards α-Glucosidase, dipeptidyl peptidase-4 and myeloperoxidase, respectively. MPO-IN-7 shows antioxidant and anti-inflammatory activity in vitro .

HY-101769

UAMC00039 dihydrochloride 1 Publications Verification	Dipeptidyl Peptidase	Cancer
UAMC00039 dihydrochloride is a potent, reversible and competitive *dipeptidyl peptidase* II inhibitor with an IC₅₀** of 0.48 nM.

Cat. No.	Product Name

HY-L040

Anti-diabetic Compound Library

780 compounds

Diabetes mellitus, usually called diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. The most common types are Type I and Type II. Type I diabetes (T1D), also called juvenile onset diabetes mellitus or insulin-dependent diabetes mellitus, is characterized by destruction of the β-cells of the pancreas and insulin is not produced, whereas type II diabetes (T2D), also called non-insulin-dependent diabetes mellitus, is characterized by a progressive impairment of insulin secretion and relative decreased sensitivity of target tissues to the action of this hormone. Type 2 diabetes accounts for the vast majority of all diabetes mellitus. Diabetes of all types can lead to complications in many parts of the body and can increase the overall risk of dying prematurely. Possible complications include kidney failure, leg amputation, vision loss and nerve damage.

The pathogenesis of diabetes is complicated, and development of the safe and effective drugs against diabetes is full of challenge. Increasing studies have confirmed that the pathogenesis of diabetes is related to various signaling pathways, such as insulin signaling pathway, AMPK pathway, PPAR regulation and chromatin modification pathways. These signaling pathways have thus become the major source of the promising novel drug targets to treat metabolic diseases and diabetes.

MCE Anti-diabetic Compound Library owns a unique collection of 780 compounds, which mainly target SGLT, PPAR, DPP-4, AMPK, Dipeptidyl Peptidase, Glucagon Receptor, etc. This library is a useful tool for discovery anti-diabetes drugs.

HY-L189

Amino Acid Metabolism Compound Library

227 compounds

Amino acids, as one of the most fundamental organic compounds in living organisms, serve not only as the basic building blocks of proteins but also but also undertake the functions of energy supply, neurotransmitter synthesis, and maintenance of internal environment stability.Amino acid metabolic enzymes are a class of enzymes involved in the metabolic processes of amino acids, catalyzing their synthesis, breakdown, transformation, and interactions with other metabolic pathways. Abnormalities in amino acid metabolic enzymes can lead to various metabolic diseases, such as phenylketonuria and hyperammonemia, etc. Therefore, actively exploring and regulating the processes of amino acid metabolism is crucial for the development of drugs related to these diseases.

MCE designs a unique collection of 227 small molecules target amino acid metabolizing enzymes, which is an important tool for studying studying amino acid metabolism processes or metabolism-related drug development.

HY-L147

Protease Inhibitor Library

598 compounds

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. Proteases play important roles in regulating multiple biological processes in all living organisms, such as regulating the fate, localization, and activity of many proteins, modulating protein-protein interactions, creating new bioactive molecules, contributing to the processing of cellular information, and generating, transducing, and amplifying molecular signals.

Proteases are important targets in drug discovery. Some protease inhibitors are often used as anti-virus drugs and anti-cancer drugs. MCE offers a unique collection of 598 protease inhibitors. MCE Protease Inhibitor Library is critical for drug discovery and development.

Cat. No.	Product Name	Type

HY-137834

Gly-Pro-AMC hydrobromide 1 Publications Verification	Fluorescent Dyes/Probes
Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .

HY-D2327

DPP-8/9 probe-1	Fluorescent Dyes/Probes
DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC₅₀ of 210 nM and 15 nM, respectively) .

Cat. No.	Product Name	Type

HY-40421

(R)-3-Fluoropyrrolidine hydrochloride	Biochemical Assay Reagents
(R)-3-Fluoropyrrolidine hydrochloride is a derivative of fluorinated pyrrolidines. The amide series of fluorinated pyrrolidines are inhibitors of dipeptidyl peptidase DP-IV. Novel α4β2 receptor ligands characterized by a 3-Fluoropyrrolidine core .

HY-137870

γ-Glutamyl-β-naphthylamide gamma-Glutamyl-beta-naphthylamide	Cell Assay Reagents
γ-Glutamyl-β-naphthylamide is a substrate for γ-glutamine peptidase. γ-Glutamyl-β-naphthylamide is specifically recognized and the peptide chain is cleaved. γ-Glutamyl-β-naphthylamide can be used to distinguish between gonococci and meningococci .

HY-W699926

(R)-Naproxen acyl-β-D-glucuronide (R)-Naproxen-β-D-glucuronide	Cell Assay Reagents
(R)-Naproxen acyl-β-D-glucuronide ((R)-Naproxen-β-D-glucuronide) is a compound metabolite with anti-inflammatory activity. (R)-Naproxen acyl-β-D-glucuronide can serve as a sensitive fluorescent substrate for proglutamyl peptidase 1, which produces a blue reaction after cleavage.

Cat. No.	Product Name	Target	Research Area

HY-P4470

Phe-Pro-Ala-pNA	Ser/Thr Protease	Cancer
Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .

HY-P4920

Mca-SEVNLDAEFK(Dnp)-NH2	Fluorescent Dye	Others
Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 .

HY-P4706

Boc-Ala-Ala-pNA	Peptides	Others
Boc-Ala-Ala-pNA is a serine peptidase

HY-P4464

Ala-Phe-Pro-pNA	Ser/Thr Protease	Cancer
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .

HY-137199

Pro-Phe-Arg-AMC	Biochemical Assay Reagents	Others
Pro-Phe-Arg-AMC is a synthetic peptide substrate of Cysteine peptidases (CPs) .

HY-P4488

H-Pro-Pro-Gln-OH	Peptides	Others
H-Pro-Pro-Gln-OH is a oligopeptide with excellent *dipeptidyl peptidase-IV (DPP-IV)* inhibitory activity .

HY-137164A

Ala-Ala-Phe-AMC TFA	Fluorescent Dye	Others
Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination .

HY-W010955

Z-Phe-Leu-OH NSC 334018	Biochemical Assay Reagents	Others
Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity .

HY-P4460

AAA-pNA	Ser/Thr Protease	Cancer
AAA-pNA is a chromogenic substrate of *Tripeptidyl-peptidase* II*. AAA-pNA can be used to test Tripeptidyl-peptidase* II activity .

HY-P4285

β-Aspartylalanine	Peptides	Others
β-Aspartylalanine is a substrate for β-aspartyl peptidase and used to measure β-aspartyl peptidase activity in fecal supernatants .

HY-P2543

Neuropeptide Y (3-36) (human, rat)	Neuropeptide Y Receptor	Metabolic Disease
Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor .

HY-P2233

Globomycin	Bacterial Antibiotic	Infection
Globomycin is a lipopeptide antibiotic and a *signal peptidase* II (LspA)** inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute *Spiroplasma melliferum* with a MIC in the range 6.25-12.5 μM .

HY-P4363

Suc-GPLGP-AMC	Peptides	Others
Suc-GPLGP-AMC is a peptide substrate of collagenase-like peptidases .

HY-111174

Diprotin A Ile-Pro-Ile	Dipeptidyl Peptidase	Metabolic Disease
Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV) .

HY-P4468

Lys-Ala-pNA	Dipeptidyl Peptidase	Others
Lys-Ala-pNA is hydrolytic substrate the of dipeptidyl peptidase (DPP) II with K_m of 0.42 mM .

HY-111174A

Diprotin A TFA Ile-Pro-Ile TFA	Dipeptidyl Peptidase	Metabolic Disease
Diprotin A TFA (Ile-Pro-Ile TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV) .

HY-P4346

MeOSuc-Ala-Ala-Pro-Met-AMC	Elastase	Others
MeOSuc-Ala-Ala-Pro-Met-AMC is a peptide substrate of elastases and chymotrypsin-like serine peptidases .

HY-P1141

GLP-1(9-36)amide	GCGR	Metabolic Disease
GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor .

HY-P1141A

GLP-1(9-36)amide TFA	GCGR	Metabolic Disease
GLP-1(9-36)amide TFA is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide TFA acts as an antagonist to the human pancreatic GLP-1 receptor .

HY-P3884

Arylomycin A2	Bacterial Antibiotic	Infection
Arylomycin A2, an antibiotic (Antibiotic), is a lipopeptide *type I signal peptidase* (SPase I)** inhibitor. Arylomycin A2 has antibacterial effects .

HY-W436471

H-Ala-Pro-AFC	Peptides	Others
H-Ala-Pro-AFC is a biological active peptide. (This is a fluorescent peptide, Abs/Em=380/500nm. It is a substrate for dipeptidyl peptidase IV (DPP IV) and Xaa-Pro dipeptidase.)

HY-P4633

γ-Glu-Tyr	Dipeptidyl Peptidase	Metabolic Disease
γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC₅₀=6.77 mM), is a potentially functional component of the type 2 diabetes diet .

HY-P3985

Bradykinin potentiator B Bradykinin potentiating peptide B	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease Others
Bradykinin potentiator B (Bradykinin potentiating peptide B) is venom of Agkistrodon halys blomhoffi. Bradykinin potentiator B is a potent ACE inhibitor. Bradykinin potentiator inhibits the activity of bradykinin inhibitory peptidase .

HY-P5826

Dynorphin B (1-9)	Opioid Receptor	Neurological Disease
Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. The formation of dynorphin B (1-9) is blocked by N-ethylmaleimide (NEM), a non-selective inhibitor of cysteine peptidases .

HY-P10389

Globomycin derivative G2A	Bacterial	Infection
Globomycin derivative G2A (Compound G2A) is an inhibitor for lipoprotein signal peptidase II (LspA), with an IC₅₀ of 604 nM. Globomycin derivative G2A inhibits E. coli, P. aeruginosa and A. baumannii, with MIC ranging from 12.5 to 32 μg/mL .

HY-P4669

LM-030 BPR277	Elastase	Inflammation/Immunology
LM-030 (BPR277) is a potent *kallikrein-related peptidase* 7 (KLK7) and epidermal elastase 2 (ELA2) inhibitor with IC₅₀**s of 6 nM and 55 nM, respectively(Example 4) . LM-030 can be used for the study of Netherton syndrome .

HY-P5323

Dabcyl-AGHDAHASET-Edans	Peptides	Others
Dabcyl-AGHDAHASET-Edans is a biological active peptide. (This is a type I signal peptidase (SPase1) substrate peptide labeled with EDANS/ DABCYL FRET pair, and contains a crucial cleavage site derived from the C-terminal region of the Staphylococcus epidermidis pre-SceD protein. Abs/Em = 340/490 nm.)

HY-P5296

Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans	Fluorescent Dye	Others
Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a fluorophore Dabsyl-labeled peptide. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans can be used to test the peptidase activity of the LasA protease of Pseudomonas aeruginosa. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans has enzyme specificity and has application value .

HY-20841

Boc-(2S)-Gly-4-pyranoyl (S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-4-Pyranoyl-Gly-OH	Amino Acid Derivatives	Others
Boc-(2S)-Gly-4-pyranoyl ((S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid) is an amino-terminally protected glycine derivative that can be used to synthesize dipeptidyl peptidase IV with antidiabetic activity .

HY-P1230

HAEGT	Dipeptidyl Peptidase GLP Receptor	Metabolic Disease
HAEGT is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide, and the sequence is His-Ala-Glu-Gly-Thr. HAEGT acts as a competitive substrate for probing prime substrate binding sites of human *dipeptidyl peptidase-IV (DPP-IV) 1, in which the N-terminal His-Ala* is catalyzed cleavage by DPP-IV. HAEGT can be used in the research of diabetes, obesity .

HY-P1624A

Teduglutide TFA ALX-0600 TFA	Nuclear Hormone Receptor 4A/NR4A FXR	Inflammation/Immunology
Teduglutide TFA is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide TFA can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide TFA can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis .

HY-P10416

Q14 Q14 peptide	Deubiquitinase Mitophagy	Others Neurological Disease
Q14 is a polypeptide derived from the USP30 (ubiquitin specific peptidase 30) transmembrane (TM) domain with the ability to inhibit the deubiquitination activity of USP30 (IC₅₀=57.2 nM). Q14 reduces USP30 activity by inhibiting the interaction between the USP30 transmembrane domain and its catalytic domain. Q14 peptide contains the LC3 interaction region (LIR) motif, which enables it to bind to the LC3 and accelerate the formation of autophagosomes, thereby promoting mitophagy. Q14 can be used in the study of neurodegenerative diseases as well as mitochondrial quality control and cell metabolism .

HY-P3580

Acetyl Gastric Inhibitory Peptide (human) Human N-acetyl GIP	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity .

HY-P3580A

Acetyl Gastric Inhibitory Peptide (human) (TFA) Human N-acetyl GIP TFA	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research of diabetes, insulin resistance and obesity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-111174

Diprotin A Ile-Pro-Ile	Microorganisms Source classification	Dipeptidyl Peptidase
Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV) .

HY-P1645

Papain 5+ Cited Publications	Carica papaya L. Structural Classification Natural Products Classification of Application Fields Source classification Caricaceae Plants Inflammation/Immunology Disease Research Fields	Cathepsin
Papain is a cysteine protease of the peptidase C1 family, which is used in food, pharmaceutical, textile, and cosmetic industries.

HY-N6584

Saikogenin A 1 Publications Verification	Triterpenes other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Inflammation/Immunology	Dipeptidyl Peptidase
Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor.

HY-N7653

Azaleatin	Flavonols Structural Classification Flavonoids Classification of Application Fields Carthamus tinctorius L. Source classification Phenols Polyphenols Metabolic Disease Plants Compositae Disease Research Fields	Dipeptidyl Peptidase
Azaleatin is an O-methylated flavonol isolated from Rhododendron species. Azaleatin is a dipeptidyl peptidase-IV inhibitor. Azaleatin can be used for the research of type-2 diabetes and obesity .

HY-N10362

Ellipyrone B	Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Metabolic Disease Disease Research Fields	Dipeptidyl Peptidase
Ellipyrone B, an antihyperglycemic γ-pyrone enclosed macrocyclic polyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC₅₀=0.48 mM) .

HY-N10360

Ellipyrone A	Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Metabolic Disease Disease Research Fields	Dipeptidyl Peptidase
Ellipyrone A, a γ-pyrone enclosed macrocyclic poyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC₅₀=0.35 mM). Ellipyrone A also has anti-carbolytic property against α-glucosidase (IC₅₀=0.74 mM) and α-amylase (IC₅₀=0.59 mM) .

HY-155704

Lyciumamide A	Structural Classification Lycium barbarum L. Source classification Phenols Polyphenols Plants Solanaceae	Others
DPP-IV-IN-5 is isolated from the fruits of Lycium barbarum. DPP-IV-IN-5 exerts moderate agonistic activities for peroxisome proliferator-activated receptor (PPARγ) with EC₅₀ values of 10.09 - 44.26 μM and also presents inhibitory activity on dipeptidyl peptidase-4 (DPPIV) with an IC₅₀ value of 47.13 μM .

HY-N10064

Ficusonolide	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Others
Ficusonolide has significant antidiabetic activity with a possible mechanism of interaction with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.

HY-N8134

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one	Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields	Dipeptidyl Peptidase
2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with *dipeptidyl peptidase-4 (DPP-4)* and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities .

HY-N12043

Bidenoside C	Structural Classification Coreopsis lanceolata L. Source classification Plants Compositae Saccharides Monosaccharides	Others
Bidenoside C (compound 10) is a polyacetylene glycoside (Polyacetylene Glycoside), which can be isolated from the flowers of Coreopsis lanceolata (Asteraceae) .

Species:	Human (42) Mouse (15) Rat (1) Cynomolgus (3)
Tag:	His (48) SUMO (2) Tag Free (9) Strep (2) Myc (2) GST (2) Trx (1) Fc (4) Flag (1)
Source:	HEK293 (29) E. coli Cell-free (1) CHO (1) Sf9 insect cells (14) P. pastoris (1) E. coli (17)

Cat. No.	Compare	Product Name	Species	Source

HY-P75280

	DPP2 Protein, Human (HEK293, His) Dipeptidyl peptidase 2; Dipeptidyl peptidase 7; DPP II; DPP7; DPP2; QPP	Human	HEK293
	The DPP2 protein is a key member of the dipeptidyl peptidase family and plays a crucial role in the degradation of specific oligopeptides. It hydrolyzes oligopeptide bonds and promotes the breakdown of peptides into amino acids, emphasizing its importance in the regulation of cellular catabolism and peptide metabolism. DPP2 Protein, Human (HEK293, His) is the recombinant human-derived DPP2 protein, expressed by HEK293 , with C-His labeled tag. The total length of DPP2 Protein, Human (HEK293, His) is 471 a.a., with molecular weight of ~60 kDa.

HY-P75712

	DPP2 Protein, Mouse (HEK293, His) Dipeptidyl peptidase 2; Dipeptidyl peptidase 7; DPP II; DPP7; DPP2; QPP	Mouse	HEK293
	DPP2 Protein plays a crucial role in the degradation of specific oligopeptides, serving as a key participant in the process. DPP2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DPP2 protein, expressed by HEK293 , with C-His labeled tag. The total length of DPP2 Protein, Mouse (HEK293, His) is 470 a.a., with molecular weight of ~65 kDa.

HY-P70112

	*Dipeptidyl peptidase* 3/DPP3 Protein, Human (His)** rHuDipeptidyl peptidase 3/DPP3, His; Dipeptidyl peptidase 3; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III; Enkephalinase B; DPP3	Human	E. coli
	According to research reports, dipeptidyl peptidase 3 (DPP3) protein, as an enzymatic entity, is able to cleave and degrade various bioactive peptides, including substrates such as angiotensin, leucine-enkephalin, and methionine-enkephalin. According to the results of multiple studies, in addition to its role in processing these bioactive peptides, DPP3 also has the ability to cleave Arg-Arg-β-naphthylamide in vitro. Dipeptidyl peptidase 3/DPP3 Protein, Human (His) is the recombinant human-derived Dipeptidyl peptidase 3/DPP3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Dipeptidyl peptidase 3/DPP3 Protein, Human (His) is 737 a.a., with molecular weight of 76-88 kDa.

HY-P72975

	*CD26/Dipeptidyl Peptidase* 4 Protein, Human (HEK293)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with tag free. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293) is 738 a.a., with molecular weight of ~95 kDa.

HY-P72976

	*CD26/Dipeptidyl Peptidase* 4 Protein, Human (HEK293, Fc)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc) is 738 a.a., with molecular weight of 120-130 kDa.

HY-P75428

	*CD26/Dipeptidyl Peptidase* 4 Protein, Mouse (HEK293, His)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Mouse	HEK293
	CD26/dipeptidyl peptidase 4 is a key cell surface receptor for T cell activation. It binds to ADA, CAV1, IGF2R and PTPRC to promote T cell proliferation and NF-kappa-B activation. CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, His) is 732 a.a., with molecular weight of ~85.9 kDa.

HY-P75429

	*CD26/Dipeptidyl Peptidase* 4 Protein, Mouse (HEK293, Fc)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Mouse	HEK293
	CD26/dipeptidyl peptidase 4 is a key cell surface receptor for T cell activation. It binds to ADA, CAV1, IGF2R and PTPRC to promote T cell proliferation and NF-kappa-B activation. CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, Fc) is 732 a.a., with molecular weight of ~122.5 kDa.

HY-P76876

	*CD26/Dipeptidyl Peptidase* 4 Protein, Cynomolgus (HEK293, His)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, His) is 733 a.a., with molecular weight of 100-130 KDa.

HY-P76877

	*CD26/Dipeptidyl Peptidase* 4 Protein, Cynomolgus (HEK293, Fc)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, Fc) is 733 a.a., with molecular weight of ~113 kDa.

HY-P76875

	*CD26/Dipeptidyl Peptidase* 4 Protein, Cynomolgus (HEK293)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with tag free. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293) is 733 a.a., with molecular weight of 92-102 kDa.

HY-P70017

	*CD26/Dipeptidyl Peptidase* 4 Protein, Human (HEK293, His)** rHuDipeptidyl peptidase 4/CD26, His; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, His) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, His) is 738 a.a., with molecular weight of 86-130 kDa.

HY-P701873

	DPP8 Protein, Human (Sf9) DPP8; Dipeptidyl peptidase 8; DP8; Dipeptidyl peptidase IV-related protein 1; DPRP-1; Dipeptidyl peptidase VIII; DPP VIII; Prolyl dipeptidase DPP8	Human	Sf9 insect cells
	The DPP8 protein cleaves N-terminal dipeptides from proteins with Pro or Ala at position 2. DPP8 Protein, Human (Sf9) is the recombinant human-derived DPP8 protein, expressed by Sf9 insect cells , with tag free. The total length of DPP8 Protein, Human (Sf9) is 898 a.a., .

HY-P701874

	DPP8 Protein, Human (Sf9, His) DPP8; Dipeptidyl peptidase 8; DP8; Dipeptidyl peptidase IV-related protein 1; DPRP-1; Dipeptidyl peptidase VIII; DPP VIII; Prolyl dipeptidase DPP8	Human	Sf9 insect cells
	The DPP8 protein cleaves N-terminal dipeptides from proteins with Pro or Ala at position 2. DPP8 Protein, Human (Sf9, His) is the recombinant human-derived DPP8 protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of DPP8 Protein, Human (Sf9, His) is 898 a.a., .

HY-P77047

	Kallikrein-15 Protein, Human (HEK293, Fc) ACO protease; KLK15; kallikrein-related peptidase 15	Human	HEK293
	Kallikrein-15 is a kallikrein (KLK) with trypsin-like activity that may promote cancer metastasis. The study found that Kallikrein-15 is only strongly expressed in mature sperm cells and not in immature germ cells. KLK15 may be able to cleave many extracellular matrix (ECM) components, interact with the extracellular matrix (ECM) receptor group, and be associated with tumorigenesis. Kallikrein-15 Protein, Human (HEK293, Fc) is the recombinant human-derived Kallikrein-15 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77048

	Kallikrein-15 Protein, Human (HEK293, His) ACO protease; KLK15; kallikrein-related peptidase 15	Human	HEK293
	Kallikrein-15 is a kallikrein (KLK) with trypsin-like activity that may promote cancer metastasis. The study found that Kallikrein-15 is only strongly expressed in mature sperm cells and not in immature germ cells. KLK15 may be able to cleave many extracellular matrix (ECM) components, interact with the extracellular matrix (ECM) receptor group, and be associated with tumorigenesis. Kallikrein-15 Protein, Human (HEK293, His) is the recombinant human-derived Kallikrein-15 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71451

	TPP2 Protein, Human (Myc, His) TPP2; Tripeptidyl-peptidase 2; TPP-2; EC 3.4.14.10; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase II; TPP-II	Human	E. coli
	TPP2 protein, a cytosolic tripeptidyl-peptidase, is a vital component of the ubiquitin-proteasome pathway, operating downstream of the 26S proteasome. It plays a crucial role in maintaining intracellular amino acid homeostasis by releasing N-terminal tripeptides from polypeptides. Furthermore, TPP2 protein is implicated in stimulating adipogenesis, contributing to processes involved in adipose tissue formation. TPP2 Protein, Human (Myc, His) is the recombinant human-derived TPP2 protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of TPP2 Protein, Human (Myc, His) is 221 a.a., with molecular weight of ~31.8 kDa.

HY-P75705

	DERP1 Protein, Dermatophagoides pteronyssinus (HEK293, His) peptidase 1; Allergen Der p I; DERP1	Others	HEK293
	DERP1 Protein, a thiol protease, selectively cleaves target proteins with distinct structural features, favoring substrates with a large hydrophobic side chain in the P2 position or basic residues. This specificity underscores DERP1's functional significance in cellular processes. DERP1 Protein, Dermatophagoides pteronyssinus (HEK293, His) is the recombinant DERP1 protein, expressed by HEK293 , with C-10*His, C-His labeled tag. The total length of DERP1 Protein, Dermatophagoides pteronyssinus (HEK293, His) is 320 a.a., with molecular weight of ~35.7 kDa.

HY-P77048A

	Kallikrein-15 Protein, Human (HEK293, C-His) ACO protease; KLK15; kallikrein-related peptidase 15	Human	HEK293
	Kallikrein-15 is a kallikrein (KLK) with trypsin-like activity that may promote cancer metastasis. The study found that Kallikrein-15 is only strongly expressed in mature sperm cells and not in immature germ cells. KLK15 may be able to cleave many extracellular matrix (ECM) components, interact with the extracellular matrix (ECM) receptor group, and be associated with tumorigenesis. Kallikrein-15 Protein, Human (HEK293, His) is the recombinant human-derived Kallikrein-15 protein, expressed by HEK293 , with C-His labeled tag.

HY-P701247

	Cathepsin C/DPPI Protein, Mouse (His-Myc) Cathepsin C; cathepsin CEC 3.4.14.1; Cathepsin J; CPPIHMS; CTSC; dipeptidyl peptidase 1; Dipeptidyl peptidase I; Dipeptidyl transferase; dipeptidyl-peptidase I; DPP1; DPPI; DPP-I; JP; JPD; PALS; PLS	Mouse	E. coli
	The cathepsin C/DPPI protein is a thiol protease that acts as a dipeptidyl peptidase with multiple substrate specificities, excluding proline at the P1 position and arginine at the P2 position. It has both exopeptidase and endopeptidase functions and can activate serine proteases such as elastase, cathepsin G, and granzymes A and B. Cathepsin C/DPPI Protein, Mouse (His-Myc) is the recombinant mouse-derived Cathepsin C/DPPI protein, expressed by E. coli , with N-10*His, C-Myc labeled tag. The total length of Cathepsin C/DPPI Protein, Mouse (His-Myc) is 110 a.a., with molecular weight of 20.1 kDa.

HY-P76112

	TPP1 Protein, Mouse (sf9, His) Tripeptidyl-peptidase 1; LPIC; Tripeptidyl Aminopeptidase; TPP-I; CLN2	Mouse	Sf9 insect cells
	TPP1, a lysosomal serine protease, acts as a non-specific lysosomal peptidase, displaying tripeptidyl-peptidase I activity in lysosomal protein degradation. Its function involves generating tripeptides from the breakdown products of other lysosomal proteinases, emphasizing its role in processing and hydrolyzing peptides within the lysosomal environment. Notably, TPP1 requires substrates with an unsubstituted N-terminus. TPP1 Protein, Mouse (sf9, His) is the recombinant mouse-derived TPP1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of TPP1 Protein, Mouse (sf9, His) is 562 a.a., with molecular weight of ~60.9 kDa.

HY-P75281

	DPP10 Protein, Human (HEK293, His) Inactive dipeptidyl peptidase 10; DPRP-3; DPP X; DPL2; DPP10	Human	HEK293
	The DPP10 protein is a key regulator that promotes cell surface expression of the potassium channel KCND2, modulating its activity and gating properties. Despite its name, DPP10 lacks dipeptidyl aminopeptidase activity. DPP10 Protein, Human (HEK293, His) is the recombinant human-derived DPP10 protein, expressed by HEK293 , with N-His labeled tag.

HY-P701428

	USP53 Protein, Human USP53; Inactive ubiquitin carboxyl-terminal hydrolase 53; Inactive ubiquitin-specific peptidase 53	Human	E. coli
	USP53 protein, a critical element in tight junctions, is essential for the survival of auditory hair cells and the maintenance of hearing function. Although lacking peptidase activity, USP53's importance is highlighted by its interaction with the TJP1:TJP2 heterodimer, suggesting nuanced involvement in the molecular architecture of tight junctions. This interaction emphasizes USP53's potential impact on cellular survival and auditory processes. USP53 Protein, Human is the recombinant human-derived USP53 protein, expressed by E. coli , with tag free. The total length of USP53 Protein, Human is 322 a.a., .

HY-P701424

	USP50 Protein, Human (Sf9) USP50; Inactive ubiquitin carboxyl-terminal hydrolase 50; Inactive ubiquitin-specific peptidase 50	Human	Sf9 insect cells
	USP50 protein, also known as ubiquitin-specific protease 50, is a protein without peptidase activity. Peptidase activity generally refers to the ability of an enzyme to cleave peptide bonds in proteins. USP50 Protein, Human (Sf9) is the recombinant human-derived USP50 protein, expressed by Sf9 insect cells , with tag free. The total length of USP50 Protein, Human (Sf9) is 338 a.a., .

HY-P701427

	USP53 Protein, Human (His, GST) USP53; Inactive ubiquitin carboxyl-terminal hydrolase 53; Inactive ubiquitin-specific peptidase 53	Human	E. coli
	USP53 protein, a critical element in tight junctions, is essential for the survival of auditory hair cells and the maintenance of hearing function. Although lacking peptidase activity, USP53's importance is highlighted by its interaction with the TJP1:TJP2 heterodimer, suggesting nuanced involvement in the molecular architecture of tight junctions. This interaction emphasizes USP53's potential impact on cellular survival and auditory processes. USP53 Protein, Human (His, GST) is the recombinant human-derived USP53 protein, expressed by E. coli , with N-6*His, N-GST labeled tag. The total length of USP53 Protein, Human (His, GST) is 322 a.a., .

HY-P75706

	DERP1 Protein, Dermatophagoides pteronyssinus (C132A, N150E, HEK293, His) peptidase 1; Allergen Der p I; DERP1	Others	HEK293
	DERP1 Protein, a thiol protease, selectively cleaves target proteins with distinct structural features, favoring substrates with a large hydrophobic side chain in the P2 position or basic residues. This specificity underscores DERP1's functional significance in cellular processes. DERP1 Protein, Dermatophagoides pteronyssinus (C132A, N150E, HEK293, His) is the recombinant DERP1 protein, expressed by HEK293 , with C-His labeled tag and C132A, N150E, , , mutation. The total length of DERP1 Protein, Dermatophagoides pteronyssinus (C132A, N150E, HEK293, His) is 320 a.a., with molecular weight of ~35.7 kDa.

HY-P701423

	USP50 Protein, Human (Sf9, GST) USP50; Inactive ubiquitin carboxyl-terminal hydrolase 50; Inactive ubiquitin-specific peptidase 50	Human	Sf9 insect cells
	USP50 protein, also known as ubiquitin-specific protease 50, is a protein without peptidase activity. Peptidase activity generally refers to the ability of an enzyme to cleave peptide bonds in proteins. USP50 Protein, Human (Sf9, GST) is the recombinant human-derived USP50 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of USP50 Protein, Human (Sf9, GST) is 338 a.a., .

HY-P70980

	TPP1 Protein, Human (HEK293, His) Tripeptidyl-peptidase 1; TPP-1; Cell Growth-Inhibiting Gene 1 Protein; Lysosomal Pepstatin-Insensitive Protease; LPIC; Tripeptidyl Aminopeptidase; Tripeptidyl-peptidase I; TPP-I; TPP1; CLN2	Human	HEK293
	TPP1, a lysosomal serine protease, acts as a non-specific lysosomal peptidase, displaying tripeptidyl-peptidase I activity in lysosomal protein degradation. Its function involves generating tripeptides from the breakdown products of other lysosomal proteinases, emphasizing its role in processing and hydrolyzing peptides within the lysosomal environment. Notably, TPP1 requires substrates with an unsubstituted N-terminus. TPP1 Protein, Human (HEK293, His) is the recombinant human-derived TPP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TPP1 Protein, Human (HEK293, His) is 544 a.a., with molecular weight of ~78.75 kDa.

HY-P703362

	DPP3 Protein, Mouse (His, Strep) Dipeptidyl peptidase 3; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III; DPP III; Enkephalinase B; Dpp3; Mus musculus; Mouse; DPP III; Aminopeptidase; Hydrolase; Metalloprotease; Protease; 3.4.14.4	Mouse	E. coli
	DPP3 Protein, Mouse (His, Strep) is the recombinant mouse-derived DPP3, expressed by E. coli , with Strep, His labeled tag. The total length of DPP3 Protein, Mouse (His, Strep) is 738 a.a.,

HY-P703379

	DPP3 Protein, Rat (His, Strep) Dipeptidyl peptidase 3; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III; DPP III; Enkephalinase B; Dpp3; Rattus norvegicus; Rat; DPP III; Aminopeptidase; Hydrolase; Metalloprotease; Protease; 3.4.14.4	Rat	E. coli
	DPP3 Protein, Rat (His, Strep) is the recombinant rat-derived DPP3, expressed by E. coli , with Strep, His labeled tag. The total length of DPP3 Protein, Rat (His, Strep) is 738 a.a.,

HY-P79459

	SENP1 Catalytic Domain Protein, Human (His) Sentrin-specific protease 1; SENP1; Sentrin/SUMO-specific protease SENP1; SUMO-Specific peptidase 1	Human	E. coli
	SENP1 Catalytic Domain Protein hydrolyzes SUMO propeptides (SUMO1, SUMO2, and SUMO3), maturing them. It also deconjugates SUMO1, SUMO2, and SUMO3 from target proteins, impacting their activities. Interacts with MTA1 and CCAR2, influencing SIRT1 interaction and transcriptional activities, showcasing its regulatory role in SUMOylation processes. SENP1 Catalytic Domain Protein, Human (His) is the recombinant human-derived SENP1 Catalytic Domain protein, expressed by E. coli , with N-His labeled tag. The total length of SENP1 Catalytic Domain Protein, Human (His) is 230 a.a., with molecular weight of ~30 kDa.

HY-P71590

	Kallikrein-14 Protein, Mouse (His) Klk14; Gk14Kallikrein-14; EC 3.4.21.-; Glandular kallikrein KLK14; mGK14; Kallikrein related-peptidase 14	Mouse	E. coli
	Kallikrein-14 protein is a serine-type endopeptidase with multiple substrate specificities and has trypsin-like and chymotrypsin-like activities. It activates/inactivates protease-activated receptors (F2R, F2RL1, F2RL3) and other kallikreins (KLK1, KLK3, KLK5, KLK11). Kallikrein-14 Protein, Mouse (His) is the recombinant mouse-derived Kallikrein-14 protein, expressed by E. coli , with N-His labeled tag.

HY-P70883

	Kallikrein-7 Protein, Mouse (HEK293, His) Kallikrein-7; Klk7; Serine protease 6; Stratum corneum chymotryptic enzyme; Thymopsin; kallikrein-related peptidase 7; PRSS6; SCCEkallikrein-7	Mouse	HEK293
	Kallikrein-7 is an important contributor to skin integrity and may catalyze the degradation of intercellular adhesive structures that are critical for continuous cell shedding.Kallikrein-7 exhibits cleavage activity against insulin A and B chains, with specificity for aromatic residues at position P1 indicating versatility in substrate recognition.Kallikrein-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kallikrein-7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7270

	Neuroserpin Protein, Human (CHO) rHuNeuroserpin; peptidase inhibitor 12; Serpin I1; SERPINI1	Human	CHO
	Neuroserpin Protein, Human (CHO) is a member of the serpin family of serine protease inhibitors, playing an important role in synaptic plasticity and memory formation in the hippocampus.

HY-P74703

	Neuroserpin Protein, Mouse (HEK293, His) Neuroserpin; peptidase inhibitor 12; Serpin I1; SERPINI1	Mouse	HEK293
	Neuroserpin is a serine protease inhibitor that significantly inhibits plasminogen activator and plasmin without affecting thrombin.In addition to their role in protease inhibition, neuroserine proteases contribute to synaptic plasticity, affecting synaptic connections in the adult nervous system.Neuroserpin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Neuroserpin protein, expressed by HEK293 , with C-His labeled tag.

HY-P74780

	LAP3 Protein, Human (HEK293, His) Cytosol aminopeptidase; LAP-3; peptidase S; LAP3; LAPEP; PEPS	Human	HEK293
	The LAP3 protein is a cytosolic metallopeptidase that serves as a catalytic entity responsible for the removal of unsubstituted N-terminal hydrophobic amino acids from a variety of peptides. The peptidase activity of LAP3 depends on the presence of Zn(2+) ions, and its substrate specificity can be modulated by binding to other cofactors. LAP3 Protein, Human (HEK293, His) is the recombinant human-derived LAP3 protein, expressed by HEK293 , with C-His labeled tag. The total length of LAP3 Protein, Human (HEK293, His) is 519 a.a., with molecular weight of ~57.6 kDa.

HY-P77196

	SERPINB10 Protein, Mouse (sf9, His) Serpin B10; Bomapin; peptidase inhibitor 10; PI-10	Mouse	Sf9 insect cells
	SERPINB10 is an important protease inhibitor that may regulate protease activity in hematopoiesis and TNF-induced apoptosis. SERPINB10 acts in both the cytoplasm and the nucleus, demonstrating versatility in influencing key cellular processes. SERPINB10 Protein, Mouse (sf9, His) is the recombinant mouse-derived SERPINB10 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SERPINB10 Protein, Mouse (sf9, His) is 397 a.a., with molecular weight of ~44 kDa.

HY-P79457

	USP2 Catalytic Domain Protein, Human (His) Ubiquitin Specific peptidase 2; UBP41; Ubiquitin-Specific-Processing Protease 2; Ubiquitin Carboxyl-Terminal Hydrolase 2; 41 KDa Ubiquitin-Specific Protease; Deubiquitinating Enzyme 2; Ubiquitin-specific Protease 2	Human	E. coli
	USP2 catalytic domain proteins act as hydrolases and target polyubiquitinated proteins such as MDM2, MDM4, and CCND1. Both isoform 1 and isoform 4 exhibit ubiquitin-specific peptidase and isopeptidase activities. USP2 Catalytic Domain Protein, Human (His) is the recombinant human-derived USP2 Catalytic Domain protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701422

	USP48 Protein, Human (Sf9, FLAG) USP48; Ubiquitin carboxyl-terminal hydrolase 48; Deubiquitinating enzyme 48; Ubiquitin thioesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; Ubiquitin-specific-processing protease 48	Human	Sf9 insect cells
	USP48 protein, a deubiquitinase, hydrolyzes ubiquitin bonds at the C-terminal Gly, processing poly-ubiquitin precursors and ubiquitinated proteins. It may regulate NF-kappa-B activation by the TNF receptor superfamily via RELA and TRAF2 interactions. With potential roles at postsynaptic sites, USP48 exhibits multifunctionality, influencing ubiquitin processing and signaling pathways involved in immune response and synaptic function. USP48 Protein, Human (Sf9, FLAG) is the recombinant human-derived USP48 protein, expressed by Sf9 insect cells , with C-Flag labeled tag. The total length of USP48 Protein, Human (Sf9, FLAG) is 1034 a.a., .

HY-P76061

	Serpin B6b Protein, Mouse (sf9, His) NK13; Serine (Or cysteine) peptidase inhibitor, clade B, member 6B	Mouse	Sf9 insect cells
	Serpin B6b protein is an important member of the serine protease inhibitor family and plays a crucial role as a serine protease inhibitor, regulating proteolytic activity.His research enhances the understanding of cellular processes related to proteolysis and its therapeutic applications.Serpin B6b Protein, Mouse (sf9, His) is the recombinant mouse-derived Serpin B6b protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P77198

	Serpin B4 Protein, Human (sf9, His) Serpin B4; Leupin; peptidase inhibitor 11; PI-11; SCCA-2	Human	Sf9 insect cells
	Serpin B4 is a protease inhibitor that may modulate the host immune response against tumor cells, suggesting a crucial role in fine-tuning immune balance. Its ability to inhibit proteases emphasizes its importance in influencing key regulatory pathways, enhancing the immune system's effectiveness against cancer cells. Serpin B4 Protein, Human (sf9, His) is the recombinant human-derived Serpin B4 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Serpin B4 Protein, Human (sf9, His) is 390 a.a., with molecular weight of ~45 kDa.

HY-P76641

	Serpin B8 Protein, Mouse (sf9, His) Cytoplasmic antiproteinase 2; CAP-2; peptidase inhibitor 8; PI-8; SERPINB8	Mouse	Sf9 insect cells
	The Serpin B8 protein plays a critical role in promoting epithelial desmosome-mediated intercellular adhesion, underscoring its importance in maintaining cell adhesion within epithelial tissues.The protein's involvement suggests an important contribution to the structural integrity and stability of desmosomes, key cellular structures that mediate adhesion between adjacent cells.Serpin B8 Protein, Mouse (sf9, His) is the recombinant mouse-derived Serpin B8 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P76837

	CNDP2 Protein, Human (sf9, His) Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; peptidase A; CN2; CPGL; HEL-S-13; PEPA	Human	Sf9 insect cells
	The CNDP2 protein is a catalyst that coordinates the oxidative cleavage of heme at the α-methylene bridge carbon, releasing carbon monoxide (CO) and generating biliverdin IXalpha. This enzymatic process releases ferrous iron from the central heme iron chelate. CNDP2 Protein, Human (sf9, His) is the recombinant human-derived CNDP2 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P71306

	Serpin B9 Protein, Human (HEK293, His) Cytoplasmic antiproteinase 3; peptidase inhibitor 9; CAP3; PI-9; Serpin B9	Human	HEK293
	The Serpin B9 Protein, a member of the serpin family, crucially regulates immune responses by specifically inhibiting granzyme B, a protease involved in immune cell-mediated apoptosis. Acting as a potent inhibitor, Serpin B9 modulates granzyme B's cytotoxic activity, fine-tuning immune responses and preventing unwarranted cell death, emphasizing its significance in maintaining immune balance. Serpin B9 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B9 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B9 Protein, Human (HEK293, His) is 376 a.a., with molecular weight of 35-40 kDa.

HY-P71303

	Serpin B1 Protein, Human (HEK293, His) Leukocyte elastase inhibitor; SERPINB1; Monocyte/neutrophil elastase inhibitor; M/NEI; peptidase inhibitor 2; PI-2	Human	HEK293
	Serpin B1 protein is an important neutrophil serine protease inhibitor that regulates innate immune responses by protecting cells from cytoplasmic proteases during stress. It inhibits various neutrophil proteases, including elastase and chymotrypsin, and blocks GZMH activity intracellularly. Serpin B1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B1 Protein, Human (HEK293, His) is 379 a.a., with molecular weight of ~44.0 kDa.

HY-P71143

	Serpin A4 Protein, Human (HEK293, His) Kallistatin; Kallikrein Inhibitor; peptidase Inhibitor 4; PI-4; Serpin A4; SERPINA4; KST; PI4	Human	HEK293
	Serpin A4 Protein inhibits tissue kallikrein's amidolytic and kininogenase activities by forming a heat- and SDS-stable equimolar complex with the enzyme. Tissue kallikrein concurrently cleaves the reactive site of Serpin A4, producing a small C-terminal fragment. The protein, existing as a monomer and occasionally forming homodimers, demonstrates its regulatory role in modulating tissue kallikrein-mediated enzymatic activities. Serpin A4 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A4 Protein, Human (HEK293, His) is 407 a.a., with molecular weight of 60-80 kDa.

HY-P75925

	METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) Methionine aminopeptidase 2; MAP 2; p67eIF2; peptidase M; Mnpep	Mouse	Sf9 insect cells
	METAP2, also known as methionine aminopeptidase 2, plays a critical role in protein synthesis by co-translationally removing N-terminal methionine from nascent proteins. This enzymatic activity is particularly pronounced when the second residue in the primary sequence is small and uncharged (including residues such as Ala, Cys, Gly, Pro, Ser, Thr, or Val). METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) is the recombinant mouse-derived METAP2/Methionine aminopeptidase 2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) is 477 a.a., with molecular weight of ~60 kDa.

HY-P701591

	LONRF2 Protein, Human LONRF2; LON peptidase N-terminal domain and RING finger protein 2; Neuroblastoma apoptosis-related protease; RING finger protein 192	Human	E. coli
	LONRF2 Protein, Human is the recombinant human-derived LONRF2 protein, expressed by E. coli , with tag free. The total length of LONRF2 Protein, Human is 753 a.a., .

HY-P701592

	LONRF2 Protein, Human (His) LONRF2; LON peptidase N-terminal domain and RING finger protein 2; Neuroblastoma apoptosis-related protease; RING finger protein 192	Human	E. coli
	LONRF2 Protein, Human (His) is the recombinant human-derived LONRF2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of LONRF2 Protein, Human (His) is 753 a.a., .

HY-P70970

	Serpin B6 Protein, Human (Trx-His) Serpin B6; Cytoplasmic Antiproteinase; CAP; peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; SERPINB6; PI6; PTI	Human	E. coli
	Serpin B6 protein acts as a potential modulator of serine proteases in the brain or blood. It inhibits cathepsin G, kallikrein 8, and thrombin, suggesting a role in protease regulation. Serpin B6 Protein, Human (Trx-His) is the recombinant human-derived Serpin B6 protein, expressed by E. coli , with N-Trx, N-6*His labeled tag. The total length of Serpin B6 Protein, Human (Trx-His) is 376 a.a., with molecular weight of 58-60 kDa.

HY-P76640

	Serpin B6 Protein, Human (sf9, His) Serpin B6; Cytoplasmic Antiproteinase; CAP; peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; SERPINB6; PI6; PTI	Human	Sf9 insect cells
	Serpin B6 protein acts as a potential modulator of serine proteases in the brain or blood. It inhibits cathepsin G, kallikrein 8, and thrombin, suggesting a role in protease regulation. Serpin B6 Protein, Human (sf9, His) is the recombinant human-derived Serpin B6 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Serpin B6 Protein, Human (sf9, His) is 375 a.a., with molecular weight of ~43 kDa.

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Cat. No.	Product Name	Chemical Structure

HY-W764737

Methylboronic acid pinacol ester-d3
Methylboronic acid pinacol ester is an orally administered compound that inhibits the activity of peptidases and imidazole derivatives. Methylboronic acid pinacol ester is used as a medicinal preparation for cancer .

HY-14291S2

Vildagliptin-13C5,15N
Vildagliptin- ¹³C₅, ¹⁵N (LAF237- ¹³C₅, ¹⁵N; NVP-LAF 237- ¹³C₅, ¹⁵N) is a ¹³C- and ¹⁵N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-161447

USP1-IN-8
USP1-IN-8 (Compound 16) is an inhibitor for ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, with IC₅₀ ≤50 nM. USP1-IN-8 inhibits proliferation of MDA-MB-436 with IC₅₀ ≤50 nM .

HY-14291S1

Vildagliptin-d7
Vildagliptin-d₇ is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].

HY-14291S

Vildagliptin-d3
Vildagliptin-d₃ is the deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1][2].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82766

	CD26 Antibody (YA2511) DPP4; ADCP2; CD26; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26; TP103; CD26	WB	Human, Mouse, Rat
	CD26 Antibody (YA2511) is a biotin-conjugated non-conjugated IgG antibody, targeting CD26, with a predicted molecular weight of 88 kDa (observed band size: 110 kDa). CD26 Antibody (YA2511) can be used for WB experiment in human, mouse, rat background.

HY-P83583

	USP14 Antibody (YA3328) TGT; tRNA guanine transglycosylase 60 kD subunit; Ubiquitin carboxyl terminal hydrolase 14; Ubiquitin specific peptidase 14; USP14	WB, ICC/IF, FC	Human, Mouse, Rat
	USP14 Antibody (YA3328) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3328), targeting USP14, with a predicted molecular weight of 56 kDa (observed band size: 56 kDa). USP14 Antibody (YA3328) can be used for WB, ICC/IF, FC experiment in human, mouse, rat background.

HY-P80715

	HtrA2 Antibody (YA726) High temperature requirement protein A2; HTRA 2; HtrA like serine protease; HtrA serine peptidase 2; HtrA; E. coli; homolog of; 2; HtrA2; HTRA2_HUMAN; mitochondrial; Omi stress regulated endoprotease; Omi stress-regulated endoprotease; PARK 13; PARK13; Pr	WB, IP	Human
	HtrA2 Antibody (YA726) is a non-conjugated and Mouse origined monoclonal antibody about 49 kDa, targeting to HtrA2 (8G11). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P81736

	APAF1 Antibody (YA1481) APAF; APAF-1; APAF1; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; Apoptotic protease-activating factor 1; CED4; DKFZp781B1145; KIAA0413	WB, IHC-P, ICC/IF	Human, Mouse
	APAF1 Antibody (YA1481) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1481), targeting APAF1, with a predicted molecular weight of 142 kDa (observed band size: 135 kDa). APAF1 Antibody (YA1481) can be used for WB, IHC-P, ICC/IF experiment in human, mouse background.

HY-P81251

	CASP4 Antibody Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-11; CASP-11; Protease ICH-3; Apoptosis related cysteine peptidase; Apoptotic cysteine protease Mih1/TX; CASP 4; CASP 4; CASP-4; CASP4; CASP4_HUMAN; CASP4_MOUSE; Caspase 4 apoptosis related cysteine peptidase; Caspase-4 subunit 2; Caspase4; ICE(rel) II; ICE(rel)-II; ICE(rel)II; ICEREL II; ICERELII; ICH 2; ICH 2 protease; ICH2; Mih1/TX; Mih1/TX; Protease ICH-2; Protease TX; TX; TX protease; EC:3.4.22.64.	WB, ELISA	Human, Rat
	CASP4 Antibody is a biotin-conjugated non-conjugated IgG antibody, targeting CASP4, with a predicted molecular weight of 43 kDa. CASP4 Antibody can be used for WB, ELISA experiment in human and rat background.

HY-P81252

	Caspase-5 p20 Antibody Caspase-5 subunit p20; Apoptosis related cysteine protease; CASP 5; CASP5; Caspase-5; Caspase5; Caspase 5 apoptosis related cysteine peptidase; caspase 5 apoptosis related cysteine protease; ICE; ICE(rel) III; ICE(rel)III; ICEREL III; ICERELIII; ICH 3; ICH 3 protease; ICH3; ICH3 protease; MGC141966; TY; TY protease.	WB, IHC-P, IHC-F, ICC/IF, ELISA	Human, Mouse
	Caspase-5 p20 Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Caspase-5 p20, with a predicted molecular weight of 48 kDa. Caspase-5 p20 Antibody can be used for WB, IHC-P, IHC-F, ICC/IF, ELISA experiments in human, mouse backgrounds.

HY-P81232

	Caspase-1 p20 Antibody caspase-1 isoform alpha p20 subunit; CASP1; ICE; IL1BC; Caspase-1 subunit p20; CASP 1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_HUMAN; CASP1_MOUSE.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat,
	Caspase-1 p20 Antibody is an unconjugated, approximately 20/46 kDa, rabbit-derived, anti-Caspase-1 p20 polyclonal antibody. Caspase-1 p20 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, background without labeling.

HY-P81529

	DPP4/CD26 Antibody (YA1274) ADCP2, CD26; DPP4; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2 (ADCP-2); Dipeptidyl peptidase IV (DPP IV); T-cell activation antigen CD26; TP103	IHC-P	Human
	DPP4/CD26 Antibody (YA1274) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1274), targeting DPP4/CD26. DPP4/CD26 Antibody (YA1274) can be used for IHC-P experiment in human background.

HY-P81084

	ACE Antibody Angiotensin Converting Enzyme 1; ACE; ACE-T; Angiotensin-converting enzyme isoform 1precursor; Dipeptidyl carboxy peptidase 1; Kininase II; ACE-1; testis-specific isoform precursor. ACE 1; ACE T; ACE1; Angiotensin converting enzyme somatic isoform; Angiotensin converting enzyme testis specific isoform; Angiotensin I converting enzyme; Angiotensin I converting enzyme 1; Angiotensin I converting enzyme peptidyl dipeptidase A 1; Carboxycathepsin; CD 143; CD143; CD143 antigen; DCP 1; DCP; DCP1; Dipeptidyl carboxypeptidase 1; MVCD3; peptidase P; Peptidyl dipeptidase A; Testicular ECA; ACE_HUMAN.	WB, IHC-P, FC	Human, Mouse
	ACE Antibody is an unconjugated, approximately 150 kDa, rabbit-derived, anti-ACE monoclonal antibody. ACE Antibody can be used for: WB,IHC-P,FC expriments in human, mouse background without labeling.

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