Search Result

Results for "

cerebral

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (7) Acyltransferase (1) Adenosine Receptor (1) Adrenergic Receptor (6) Akt (5) Amino Acid Derivatives (1) Aminopeptidase (1) AMPK (1) Amyloid-β (5) Angiotensin Receptor (1) Antibiotic (2) Apoptosis (28) Aquaporin (1) Bacterial (4) Bcl-2 Family (3) Biochemical Assay Reagents (1) Bradykinin Receptor (1) Calcium Channel (11) CaMK (1) Cannabinoid Receptor (2) Caspase (5) Chloride Channel (1) Cholecystokinin Receptor (3) Cholinesterase (ChE) (4) Complement System (1) Cytochrome P450 (1) DAPK (1) Dopamine Receptor (6) Drug Derivative (2) Drug Metabolite (1) Dynamin (1) Endogenous Metabolite (20) Endothelin Receptor (3) ERK (1) Fungal (2) GABA Receptor (6) GHSR (1) Glutaminase (1) GlyT (1) Guanylate Cyclase (5) HDAC (1) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (4) Histone Methyltransferase (1) HIV (2) HSP (1) IGF-1R (1) iGluR (13) Influenza Virus (1) Interleukin Related (5) Isotope-Labeled Compounds (10) Keap1-Nrf2 (3) mAChR (6) MDM-2/p53 (2) MEK (1) mGluR (2) Microtubule/Tubulin (5) MMP (3) Monoamine Oxidase (6) nAChR (5) Neurokinin Receptor (1) NF-κB (7) NKCC (2) NO Synthase (11) NOD-like Receptor (NLR) (2) Nucleoside Antimetabolite/Analog (11) Nucleoside Transporters (1) PARP (3) Phosphatase (1) Phosphodiesterase (PDE) (4) PI3K (3) PKC (1) PKD (1) Potassium Channel (6) Prolyl Endopeptidase (PREP) (1) Reactive Oxygen Species (5) Reverse Transcriptase (1) RIP kinase (1) SARS-CoV (3) Sigma Receptor (1) Sodium Channel (5) Telomerase (2) Thrombin (1) Thyroid Hormone Receptor (1) TMV (1) TNF Receptor (3) Toll-like Receptor (TLR) (1) Trk Receptor (2) TRP Channel (3) Xanthine Oxidase (1) α-synuclein (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (44) Endocrinology (7) Infection (16) Inflammation/Immunology (48) Metabolic Disease (10) Neurological Disease (160)
Oligonucleotides:	Nucleosides and their Analogs (1)

224

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-143333

Nrf2 activator-3	Keap1-Nrf2	Neurological Disease Inflammation/Immunology
Nrf2 activator-3 is a potent Nrf2 activator. Nrf2 activator-3 is used for cerebral ischemic injury research .

HY-153595

DAPK-IN-2	DAPK	Cardiovascular Disease
DAPK-IN-2 is a DAPK inhibitor. DAPK-IN-2 can be used for the research of cerebral infarction and ischemic diseases .

HY-105559A

Viquidil hydrochloride Quinotoxine hydrochloride	Others	Cardiovascular Disease
Viquidil hydrochloride (Quinotoxine hydrochloride), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil hydrochloride shows antithrombotic activity .

HY-N2014

Verbenalin 1 Publications Verification	SARS-CoV	Infection Inflammation/Immunology
Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury .

HY-102092

FR139317 PD 147953	Endothelin Receptor	Cardiovascular Disease
FR139317 (PD 147953) is a selective ET_A receptor antagonist. FR139317 inhibits cerebral activation by intraventricular endothelin-1 in conscious rats. FR139317 also ameliorates cerebral vasospasm in dogs .

HY-105925

Mefenidil MCN 2378	Adrenergic Receptor	Cardiovascular Disease
Mefenidil (MCN 2378) is a selective cerebral vasodilator that is not affected by beta-adrenergic blockade. Mefenidil can be used in the study of cardiovascular disease. In monkey models, mefenidil preferentially increases cerebral blood flow over systemic (femoral) blood flow. Mefenidil is also able to reduce systemic arterial pressure in anesthetized dogs.

HY-107563

ROS 234	Histamine Receptor	Inflammation/Immunology
ROS 234 is a potent H3 antagonist, with a pK_B of 9.46 for Guinea-pig ileum H₃-receptor, a pK_i of 8.90 for Rat cerebral cortex H₃-receptor, and a ED₅₀ of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access .

HY-107563A

ROS 234 dioxalate	Histamine Receptor	Inflammation/Immunology
ROS 234 dioxalate is a potent H3 antagonist, with a pK_B of 9.46 for Guinea-pig ileum H₃-receptor, a pK_i of 8.90 for Rat cerebral cortex H₃-receptor, and a ED₅₀ of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 dioxalate diaplays poor central access .

HY-118570

5-Oxoprolyltryptophan	Others	Neurological Disease
5-Oxoprolyltryptophan is a model substrate for investigating the increase of serotonin at the cerebral level .

HY-105559

Viquidil Quinotoxine	Others	Cardiovascular Disease
Viquidil (Quinotoxine), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil shows antithrombotic activity .

HY-134555

A3AR antagonist 4	Adenosine Receptor	Neurological Disease
A3AR antagonist 4 (Compd 1) is an A3AR antagonist, with K_i values of 30.8 nM (hA₃) and 203 nM (hA₁), repectively. A3AR antagonist 4 (Compd 1) can be used for the study of cerebral ischemia .

HY-139427

3-Methylglutaconic acid β-Methylglutaconic acid	GABA Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease
3-Methylglutaconic acid is the major metabolites accumulating in 3-Methylglutaconic aciduria (MGTA). 3-Methylglutaconic acid can induce lipid oxidative damage and protein oxidative. 3-Methylglutaconic acid decreases the non-enzymatic antioxidant defenses in cerebral cortex supernatants to elicit oxidative stress in the cerebral cortex. 3-Methylglutaconic acid can be used for brain damage disease research .

HY-17032A

Indeloxazine hydrochloride (rac)-AS1069562 hydrochloride; YM-08054	5-HT Receptor	Neurological Disease
Indeloxazine hydrochloride is a 5-HT receptor and norepinephrine (NE) reuptake inhibitor. Indeloxazine hydrochloride is an antidepressant and cerebral activator .

HY-15114

S 17092 S 17092-1	Prolyl Endopeptidase (PREP)	Neurological Disease
S 17092 (S 17092-1) is a potent cerebral prolyl-endopeptidase (PEP) inhibitor with an IC₅₀ of 1.2 nM. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging .

HY-121186

Bevantolol hydrochloride	Adrenergic Receptor Calcium Channel	Cardiovascular Disease Neurological Disease Metabolic Disease
Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pK_i values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca ²⁺ antagonist .

HY-111298

TG 41	GABA Receptor	Neurological Disease
TG 41 is positive modulator of GABAA receptor. TG 41 enhances the binding both of GABA and of Flunitrazepam to rat cerebral cortical membranes .

HY-N2014R

Verbenalin (Standard)	SARS-CoV	Infection Inflammation/Immunology
Verbenalin (Standard) is the analytical standard of Verbenalin. This product is intended for research and analytical applications. Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury .

HY-101101

L-701252	iGluR	Neurological Disease
L-701252 is a potent antagonist of glycine site NMDA receptor with an IC₅₀ of 420 nM. L-701252 provides a small degree of neuroprotection in global cerebral ischaemia .

HY-121186R

Bevantolol (hydrochloride) (Standard)	Adrenergic Receptor Calcium Channel	Neurological Disease Metabolic Disease
Bevantolol (hydrochloride) (Standard) is the analytical standard of Bevantolol (hydrochloride). This product is intended for research and analytical applications. Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pK_i values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca ²⁺ antagonist .

HY-162164

Neuroprotective agent 3	Others	Neurological Disease
Neuroprotective agent 3 (Compound 21a) is an antioxidant that exhibits neuroprotective effects. Neuroprotective agent 3 significantly increases neuronal viability and induces neuroprotection, as well as improves neurological deficit scores in an in vivo model of transient cerebral ischemia .

HY-100957

Dilazep dihydrochloride	Nucleoside Transporters	Cardiovascular Disease
Dilazep dihydrochloride is an inhibitor of adenosine uptake. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep dihydrochloride also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides .

HY-77490A

1,3-Butanediol	Endogenous Metabolite	Cardiovascular Disease Neurological Disease
1,3-Butanediol, an ethanol dimer providing a source of calories for human nutrition. 1,3-Butanediol is converted in the body to β-hydroxybutyrate and has cerebral protective and hypoglycaemic effect .

HY-B1715

Oxiracetam ISF2522	GABA Receptor NO Synthase	Neurological Disease Inflammation/Immunology
Oxiracetam (ISF2522) is an orally active and a BBB-penatrable cyclic derivative of γ-aminobutyric acid (GABA). Oxiracetam reaches the hippocampus and cerebral cortex in high concentrations. Oxiracetam can promote cognitive function and regulate inflammatory response, with powerful neuroprotective effects. Oxiracetam can be used in the study of central nervous system diseases .

HY-101247

MTPG	mGluR	Neurological Disease
MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release .

HY-P99886

Pexelizumab h5G1. 1-SC	Complement System Apoptosis	Cardiovascular Disease Neurological Disease
Pexelizumab (h5G1. 1-SC) is a humanized scFv monoclonal antibody directed against the C5 complement component. Pexelizumab inhibits apoptosis and leukocyte infiltration. Pexelizumab can be used for the research of cerebral IR injury and myocardial infarction .

HY-77490AR

1,3-Butanediol (Standard)	Endogenous Metabolite	Cardiovascular Disease Neurological Disease
1,3-Butanediol (Standard) is the analytical standard of 1,3-Butanediol. This product is intended for research and analytical applications. 1,3-Butanediol, an ethanol dimer providing a source of calories for human nutrition. 1,3-Butanediol is converted in the body to β-hydroxybutyrate and has cerebral protective and hypoglycaemic effect .

HY-B1090

Cinnarizine	Calcium Channel Histamine Receptor	Cardiovascular Disease Endocrinology
Cinnarizine is an antihistamine and a calcium channel blocker, promote cerebral blood flow, used to treat cerebral apoplexy, post-trauma cerebral symptoms, and cerebral arteriosclerosis.

HY-101333

CPPG (RS)-CPPG	mGluR	Neurological Disease
CPPG ((RS)-CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC₅₀=2.2 nM) over group II (IC₅₀=46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors .

HY-N2045

Musk ketone 1 Publications Verification	PI3K Akt Apoptosis Cytochrome P450	Neurological Disease
Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis .

HY-122218

JHU-083 4 Publications Verification	Glutaminase	Neurological Disease
JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b ⁺ cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .

HY-16923A

Crobenetine hydrochloride BIII-890 hydrochloride; BIII-890 CL	Sodium Channel	Neurological Disease
Crobenetine hydrochloride (BIII-890 hydrochloride) is the hydrochloride form of Crobenetine (HY-16923). Crobenetine hydrochloride is a selective inhibitor for Na ⁺ channel. Crobenetine hydrochloride displaces ^3HBTX from site 2 of the Na ⁺ channel (IC₅₀=49 nM) in rat brain synaptosomes, exhibits only low binding affinity for other receptors and ion channels. Crobenetine hydrochloride protects brain tissue from the deleterious effects of focal cerebral ischemia in rodents .

HY-B1238

Pronethalol 1 Publications Verification (±)-Pronethalo	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Pronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias and limits the cerebral arteriovenous malformation (AVMs) .

HY-B1238A

Pronethalol hydrochloride (±)-Pronethalo hydrochloride	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Pronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias, and limits the cerebral arteriovenous malformation (AVMs) .

HY-12882A

Ifenprodil tartrate 5+ Cited Publications	iGluR Potassium Channel	Neurological Disease
Ifenprodil tartrate is a typical noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC₅₀=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC₅₀=146 μM) . Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has the potential to be a cerebral vasodilator .

HY-119274

BN-82451 dihydrochloride	Others	Neurological Disease
BN-82451 dihydrochloride, an orally active and CNS-penetrated antioxidant and a multitargeting neuroprotective agent, exert a significant protection in experimental animal models mimicking aspects of cerebral ischemia, Parkinson disease, Huntington disease, and more particularly amyotrophic lateral sclerosis .

HY-N8249

Cynandione A	nAChR Interleukin Related	Inflammation/Immunology
Cynandione A is an acetophenone that can be isolated from Cynanchum Wilfordii Radix. Cynandione A protects hepatocytes and cortical neurons from toxicity and improves neurological deficits in a rat model of cerebral ischemia. On the other hand, cynandione A has significant anti-inflammatory effects and inhibits inflammation by activating macrophage α7 nAChR and IL-10 expression .

HY-145243

PDPOB	Apoptosis	Others
PDPOB is a phenyl carboxylic acid derivative. PDPOB displays protective roles against OGD/R-evoked multiaspect neuronal deterioration in SH-SY5Y cells, as evidenced by alleviated mitochondrial dysfunction, oxidative stress, and apoptosis. PDPOB has the potential for the research of cerebral ischemia .

HY-16923

Crobenetine BIII-890; BIII-890 CL free acid	Sodium Channel	Neurological Disease
Crobenetine (BIII-890), a benzomorphan derivative, is a potent, selective, and highly use-dependent Na ⁺ channel blocker. Crobenetine displaces ^[3H]BTX from site 2 of the Na ⁺ channel (IC₅₀=49 nM) in rat brain synaptosomes, yet exhibits only low binding affinity for other receptors and ion channels. Crobenetine protects brain tissue from the deleterious effects of focal cerebral ischemia in rodents .

HY-10932

Aniracetam Ro 13-5057	nAChR iGluR	Neurological Disease
Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects. Aniracetam potentiates the ionotropic quisqualate (iQA) responses in the CA1 region of rat hippocampal slices. Aniracetam also potentiates the excitatory post synaptic potentials (EPSPs) in Schaffer collateral-commissural synapses. Aniracetam can prevents the CO₂-induced impairment of acquisition in hypercapnia model rats. Aniracetam can be used to research cerebral dysfunctional disorders .

HY-P10401

TAT-GluR6-9c	Apoptosis iGluR	Cardiovascular Disease Neurological Disease
TAT-GluR6-9c is a GluR6-PSD95 interaction blocker. By regulating the GluR6 mediated signaling pathway, TAT-GluR6-9c inhibits the activation of JNK and phosphorylation of c-Jun, reduces the expression of Fas L and thus reduces the occurrence of apoptosis. TAT-GluR6-9c can be used to study cerebral ischemia and neuroprotective strategies .

HY-135478

LY393615 NCC1048	Calcium Channel Sodium Channel	Neurological Disease
LY393615 (NCC1048) is a novel neuronal Ca ²⁺ (calcium channel) and Na ⁺ channel (sodium channel) blocker with IC₅₀s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research .

HY-100206

5α-Androstane-3β,5,6β-triol	AMPK	Neurological Disease
5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo .

HY-135478A

LY393615 free base NCC1048 free base	Calcium Channel Sodium Channel	Neurological Disease
LY393615 (NCC1048) free base is a novel neuronal Ca ²⁺ (calcium channel) and Na ⁺ channel (sodium channel) blocker with IC₅₀s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 free base has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research .

HY-10932R

Aniracetam (Standard)	nAChR iGluR	Neurological Disease
Aniracetam (Standard) is the analytical standard of Aniracetam. This product is intended for research and analytical applications. Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects. Aniracetam potentiates the ionotropic quisqualate (iQA) responses in the CA1 region of rat hippocampal slices. Aniracetam also potentiates the excitatory post synaptic potentials (EPSPs) in Schaffer collateral-commissural synapses. Aniracetam can prevents the CO₂-induced impairment of acquisition in hypercapnia model rats. Aniracetam can be used to research cerebral dysfunctional disorders .

HY-P5947

Tat-HA-NR2B9c	HIV	Neurological Disease
Tat-HA-NR2B9 contains a fragment of the cellmembrane transduction domain of HIV-1 Tat, a influenza virus hemagglutinin (HA) epitope-tag, and the C-terminal 9 amino acids of NR2B (NR2B9c). Tat-HA-NR2B9 reduces infarct size and improves neurological functions in ischemia-induced cerebral injury in the rats

HY-117983

RU-505	Amyloid-β	Neurological Disease
RU-505 is an effective β-amyloid (Aβ)-fibrinogen interaction inhibitor with IC₅₀s of 5.00 and 2.72 μM in fluorescence polarization (FP) and AlphaLISA assays, respectively. RU-505 is highly permeable to the BBB. RU-505 reduces cerebral amyloid angiopathy (CAA). RU-505 can be used for the research of Alzheimer’s disease (AD) .

HY-P10275

Tat-NTS peptide	Apoptosis	Neurological Disease
Tat-NTS peptide is a cell-penetrating peptide with neuroprotective effects. Tat-NTS peptide can specifically inhibit the nuclear translocation of ANXA1 and reduce neuronal apoptosis in ischemic areas. Moreover, Tat-NTS peptide can reduce the volume of cerebral ischemic infarction and can be used in the research of ischemic stroke .

HY-17352

Clazosentan Ro 61-1790; VML 588; AXV-034343	Endothelin Receptor	Cardiovascular Disease
Clazosentan (Ro 61-1790) is a selective endothelin A (ET_A) receptor antagonist. Clazosentan inhibits ET-1-mediated vasoconstriction. Clazosentan prevents cerebral vasospasm, vasospasm-related cerebral infarction .

HY-17352A

Clazosentan disodium Ro 61-1790 disodium; VML 588 disodium; AXV-034343 disodium	Endothelin Receptor	Cardiovascular Disease
Clazosentan disodium (Ro 61-1790) is a selective endothelin A (ET_A) receptor antagonist. Clazosentan disodium inhibits ET-1-mediated vasoconstriction. Clazosentan disodium prevents cerebral vasospasm, vasospasm-related cerebral infarction .

HY-126049

(S)-Oxiracetam (S)-(-)-Oxiracetam; (S)-ISF2522	Apoptosis	Neurological Disease
(S)-oxiracetam (S-ORC) is an inhibitor targeting apoptosis. S-ORC reduces brain infarct size and lessens neurological dysfunction in middle cerebral artery occlusion/reperfusion (MCAO/R) models. S-ORC prevents neuronal apoptosis via activating PI3K/Akt/GSK3β signaling pathway via α7 nAChR after ischemic stroke. S-ORC can prevent neuronal death after ischemic stroke .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2014

Verbenalin 1 Publications Verification	Infection Structural Classification Iridoids Classification of Application Fields Terpenoids Verbenaceae Source classification Verbena officinalis Linn. Plants Inflammation/Immunology Disease Research Fields	SARS-CoV
Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury .

HY-77490A

1,3-Butanediol	Cardiovascular Disease Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,3-Butanediol, an ethanol dimer providing a source of calories for human nutrition. 1,3-Butanediol is converted in the body to β-hydroxybutyrate and has cerebral protective and hypoglycaemic effect .

HY-12882A

Ifenprodil tartrate 5+ Cited Publications	Alkaloids Piperidine Alkaloids Neurological Disease Classification of Application Fields Crassulaceae Source classification Sedum sarmentosum Bunge Plants Disease Research Fields	iGluR Potassium Channel
Ifenprodil tartrate is a typical noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC₅₀=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC₅₀=146 μM) . Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has the potential to be a cerebral vasodilator .

HY-B0910A

Pyrithioxin dihydrochloride Pyritinol dihydrochloride; Pyridoxine disulfide dihydrochloride; Vitamin B6 disulfide dihydrochloride	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pyrithioxin dihydrochloride is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.

HY-107802

Breviscapine Breviscapinun	Structural Classification Natural Products Source classification Plants Compositae Erigeron breviscapus (Vant.) Hand.-Mazz.	NF-κB Interleukin Related
Breviscapine is a crude flavonoid extract of Breviscapine, which is more than 85% of the active ingredient, Breviscapine. Breviscapine has a wide range of cardiovascular pharmacological activities, such as increasing blood flow, improving microcirculation, dilating blood vessels, reducing blood viscosity, promoting fibrinolysis, inhibiting platelet aggregation and thrombosis. Breviscapine has been used in the study of cerebral infarction and its sequelae, cerebral thrombosis, coronary heart disease and angina pectoris .

HY-B0647

Butylphthalide 4 Publications Verification 3-n-Butylphthalide; 3-Butylphthalide	Structural Classification Natural Products Source classification Dicerothamnus rhinocerotis Umbelliferae Plants Baccharis sarothroides A.Gray	Others
Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models.

HY-N2014R

Verbenalin (Standard)	Structural Classification Iridoids Terpenoids Verbenaceae Source classification Verbena officinalis Linn. Plants	SARS-CoV
Verbenalin (Standard) is the analytical standard of Verbenalin. This product is intended for research and analytical applications. Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury .

HY-77490AR

1,3-Butanediol (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
1,3-Butanediol (Standard) is the analytical standard of 1,3-Butanediol. This product is intended for research and analytical applications. 1,3-Butanediol, an ethanol dimer providing a source of calories for human nutrition. 1,3-Butanediol is converted in the body to β-hydroxybutyrate and has cerebral protective and hypoglycaemic effect .

HY-N8249

Cynandione A	Apocynaceae Structural Classification Source classification Phenols Polyphenols Plants Cynanchum boudieri H. Lév. & Vaniot	nAChR Interleukin Related
Cynandione A is an acetophenone that can be isolated from Cynanchum Wilfordii Radix. Cynandione A protects hepatocytes and cortical neurons from toxicity and improves neurological deficits in a rat model of cerebral ischemia. On the other hand, cynandione A has significant anti-inflammatory effects and inhibits inflammation by activating macrophage α7 nAChR and IL-10 expression .

HY-B0910

Pyrithioxin Pyritinol; Pyridoxine disulfide; Vitamin B6 disulfide	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Pyrithioxin is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.

HY-B0158

Cytidine 4 Publications Verification Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms other families Animals Source classification Disease markers Nervous System Disorder Plants Endogenous metabolite	Nucleoside Antimetabolite/Analog Endogenous Metabolite
Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-116126

Leuhistin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Aminopeptidase
Leuhistin is an AP-M (aminopeptidase-M) inhibitor. AP-M is an inactivating enzyme of bioactive peptides in cerebral membranes. Leuhistin can be produced by Bacillus laterosporus BMI156-14F1 .

HY-P2813

Hirudin	Cardiovascular Disease Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields Cancer	Thrombin Apoptosis
Hirudin is a thrombin inhibitor with blood anticoagulant property. Hirudin has potent anti-thrombotic, wound repair, anti-fibrosis, anti-tumor and anti-hyperuricemia effects. Hirudin also affects diabetic complications, cerebral hemorrhage, and others .

HY-122935

Nigranoic acid	Infection Triterpenes Classification of Application Fields Terpenoids Source classification Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.	HIV Reverse Transcriptase
Nigranoic acid is a triterpenoid separated from Schisandra chinensis. Nigranoic acid inhibits HIV-1 reverse transcriptase. Nigranoic acid exhibits protective effects on brain through PARP/AIF signaling pathway in cerebral ischemia-reperfusion animal model .

HY-N0507

Rosavin	Structural Classification Simple Phenylpropanols Rhodiola rosea Linn. Crassulaceae Source classification Phenylpropanoids Plants	TNF Receptor Interleukin Related
Rosavin, an orally bioactive phenylpropanoid from Rhodiola rosea L. (RRL), is an adaptogen that enhances the body’s response to environmental stress. Rosavin significantly influences bone tissue metabolism by inhibiting osteoclastogenesis and promoting osteoblast differentiation, also impacts various diseases, demonstrating antidepressant, adaptogenic, and anxiolytic effects in mouse models. Additionally, Rosavin improves survival, reducing intestinal damage in irradiated rats and Ischemia-reperfusion(I/R)-induced cerebral injury in vivo by regulating inflammation and oxidative stress, making it a promising candidate for research in radiation-induced intestinal injury, I/R-induced cerebral injury and osteoporosis .

HY-N0045

Ginsenoside Rg1 Maximum Cited Publications 8 Publications Verification Panaxoside A; Panaxoside Rg1	Panax ginseng C. A. Meyer Triterpenes Structural Classification Neurological Disease Classification of Application Fields Anti-aging Terpenoids Source classification Plants Disease Research Fields Araliaceae Cancer	Amyloid-β NF-κB Apoptosis
Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.

HY-B0647R

Butylphthalide (Standard)	Structural Classification Natural Products Source classification Dicerothamnus rhinocerotis Umbelliferae Plants Baccharis sarothroides A.Gray	Others
Butylphthalide (Standard) is the analytical standard of Butylphthalide. This product is intended for research and analytical applications. Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models.

HY-N11911

Verazine (-)-Verazine	Structural Classification Alkaloids Other Alkaloids Source classification Veratrum maackii Regel Plants Melanthiaceae	Fungal
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases .

HY-N0507R

Rosavin (Standard)	Structural Classification Simple Phenylpropanols Rhodiola rosea Linn. Crassulaceae Source classification Phenylpropanoids Plants	TNF Receptor Interleukin Related
Rosavin (Standard) is the analytical standard of Rosavin. This product is intended for research and analytical applications. Rosavin, an orally bioactive phenylpropanoid from Rhodiola rosea L. (RRL), is an adaptogen that enhances the body’s response to environmental stress. Rosavin significantly influences bone tissue metabolism by inhibiting osteoclastogenesis and promoting osteoblast differentiation, also impacts various diseases, demonstrating antidepressant, adaptogenic, and anxiolytic effects in mouse models. Additionally, Rosavin improves survival, reducing intestinal damage in irradiated rats and Ischemia-reperfusion(I/R)-induced cerebral injury in vivo by regulating inflammation and oxidative stress, making it a promising candidate for research in radiation-induced intestinal injury, I/R-induced cerebral injury and osteoporosis .

HY-N4268

Tenuifoliside B	Source classification Polygalaceae Phenols Polyphenols Plants Polygala tenuifolia Willd.	Others
Tenuifoliside B, a component isolated from Polygalae Radix, inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. Tenuifoliside B shows potential cognitive improvement and cerebral protective effects. Tenuifoliside B has potential to become an anti-AD lead compound .

HY-125773

β-cyano-L-Alanine Beta-cyano-l-alanine	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates . β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury .

HY-N0496

Ruscogenin 3 Publications Verification	Ophiopogon japonicus (L. f.) Ker-Gawl. Cardiovascular Disease Structural Classification Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields Steroids	NOD-like Receptor (NLR)
Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity .

HY-N0745

Senkyunolide I	Natural Products Classification of Application Fields Source classification Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields Inflammation/Immunology	Caspase
Senkyunolide I, isolated from Ligusticum chuanxiong Hort, is an anti-migraine compound. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3 .

HY-N7930

Crenulatin	Structural Classification Classification of Application Fields Source classification Crassulaceae Other Diseases Plants Disease Research Fields Rhodiola crenulata (HK. f. et.Thoms) H. Ohba Saccharides	Others
Crenulatin is a gallotannin that can be isolated from Rhodiola rosea. Crenulatin can be used as a biomarker to identify potentially adulterated R. rosea products. Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, via regulating Fas/Bcl-2 expression and caspase-3 activity .

HY-113149

Argininosuccinic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Argininosuccinic acid participates in the fourth step of the urea cycle, with being cleaved to arginine and fumaric acid by argininosuccinic acid lyase (ASL). Argininosuccinic acid reduces reduced glutathione (GSH) level, and increases the production of reactive oxygen species in cerebral cortex and striatum. Argininosuccinic acid causes lipid peroxidation and protein oxidation, and induces oxidative stress in the developing rat brain .

HY-N12249

7-Deoxy-trans-dihydronarciclasine	Hosta plantaginea (Lam.) Aschers. Structural Classification Alkaloids Source classification Quinoline Alkaloids Plants Asparagaceae Juss.	Amyloid-β TMV
7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC₅₀: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice .

HY-113149A

Argininosuccinic acid disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain .

HY-N12715

Valerena-4,7(11)-diene	Structural Classification Terpenoids Sesquiterpenes Source classification Nardostachys jatamansi (D. Don) DC. Plants Valerianaceae	Others
Valerena-4,7(11)-diene is a tranquilizer. Valerena-4,7(11)-diene suppresses stress-induced excitatory behaviors. Valerena-4,7(11)-diene is expressed via olfactory stimulation and pulmonary absorption .

HY-N0045R

Ginsenoside Rg1 (Standard) Panaxoside A (Standard); Panaxoside Rg1 (Standard)	Panax ginseng C. A. Meyer Triterpenes Structural Classification Neurological Disease Classification of Application Fields Anti-aging Terpenoids Source classification Plants Disease Research Fields Araliaceae Cancer	Amyloid-β NF-κB Apoptosis
Ginsenoside Rg1 (Standard) is the analytical standard of Ginsenoside Rg1. This product is intended for research and analytical applications. Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.

HY-N6967

Levomenol (-)-α-Bisabolol	Structural Classification other families Terpenoids Sesquiterpenes Source classification Plants	Apoptosis
Levomenol ((-)-α-Bisabolol), a monocyclic sesquiterpene alcohol, exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. Levomenol also has neuroprotective effects and prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Levomenol attenuates nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain. Orally active .

HY-B0158R

Cytidine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms other families Animals Source classification Disease markers Nervous System Disorder Plants Endogenous metabolite	Nucleoside Antimetabolite/Analog Endogenous Metabolite
Cytidine (Standard) is the analytical standard of Cytidine. This product is intended for research and analytical applications. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function . In Vivo:Cytidine decreases glutamate/glutamine levels and induces earlier improvement of depressive symptoms .

HY-N0496R

Ruscogenin (Standard)	Ophiopogon japonicus (L. f.) Ker-Gawl. Structural Classification Liliaceae Source classification Plants Steroids	NOD-like Receptor (NLR)
Ruscogenin (Standard) is the analytical standard of Ruscogenin. This product is intended for research and analytical applications. Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity .

HY-N1485

Cycloastragenol 5 Publications Verification Astramembrangenin; Cyclosieversigenin	Triterpenes Structural Classification other families Terpenoids Source classification Plants	Telomerase
Cycloastragenol (Astramembrangenin), the active form of astragaloside IV, has anti-oxidant, anti-inflammatory, anti-aging, anti-apoptotic, and cardiovascular protective effects. Cycloastragenol is a potent telomerase activator and can lengthen telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties .

HY-N1485R

Cycloastragenol (Standard)	Triterpenes Structural Classification other families Terpenoids Source classification Plants	Telomerase
Cycloastragenol (Standard) is the analytical standard of Cycloastragenol. This product is intended for research and analytical applications. Cycloastragenol (Astramembrangenin), the active form of astragaloside IV, has anti-oxidant, anti-inflammatory, anti-aging, anti-apoptotic, and cardiovascular protective effects. Cycloastragenol is a potent telomerase activator and can lengthen telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties .

HY-N6967R

Levomenol (Standard)	Structural Classification other families Terpenoids Sesquiterpenes Source classification Plants	Apoptosis
Levomenol (Standard) is the analytical standard of Levomenol. This product is intended for research and analytical applications. Levomenol ((-)-α-Bisabolol), a monocyclic sesquiterpene alcohol, exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. Levomenol also has neuroprotective effects and prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Levomenol attenuates nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain. Orally active .

HY-N0361

Dihydrocapsaicin 2 Publications Verification	Alkaloids Structural Classification Monophenols Capsicum annuum L. Classification of Application Fields Other Alkaloids Source classification Phenols Metabolic Disease Solanaceae Plants Disease Research Fields	TRP Channel Reactive Oxygen Species Apoptosis Caspase Bcl-2 Family Akt PI3K
Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat .

HY-N0361R

Dihydrocapsaicin (Standard)	Alkaloids Structural Classification Monophenols Capsicum annuum L. Other Alkaloids Source classification Phenols Solanaceae Plants	TRP Channel Reactive Oxygen Species Apoptosis Caspase Bcl-2 Family Akt PI3K
Dihydrocapsaicin (Standard) is the analytical standard of Dihydrocapsaicin. This product is intended for research and analytical applications. Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat .

HY-N0408R

Picroside II (Standard)	Structural Classification Iridoids Terpenoids Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell	NF-κB Reactive Oxygen Species Apoptosis Influenza Virus
Picroside II (Standard) is the analytical standard of Picroside II. This product is intended for research and analytical applications. Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways . Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury. Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities .

HY-130398

Aerophobin-2	Structural Classification Natural Products Marine natural products Source classification Sponge	α-synuclein
Aerophobin-2 is a bromine compound, which can be isolated from sponge Verongia aerophoba. Aerophobin-2 inhibits aggregation of α-synuclein (α-syn) and phosphorylated α-synuclein (pSyn), exhibits neuroprotective efficacy .

HY-B2167R

Docosahexaenoic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite Cardiovascular System Disorder	Endogenous Metabolite
Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC₅₀ for RXRα activation by DHA is about 5-10 μM fatty acid . In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .

Cat. No.	Product Name	Chemical Structure

HY-B0158S

Cytidine-d2
Cytidine-d₂ is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3].

HY-B0158S4

Cytidine-d1
Cytidine-d is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catechol

HY-B0647S1

Butylphthalide-d3
Butylphthalide-d₃ is the deuterium labeled Butylphthalide. Butylphthalide(3-n-Butylphthalide), an anti-cerebral-ischemia agent, is first isolated from the seeds of celery and showes efficacy in animal models of stroke.

HY-B0158S1

Cytidine-13C
Cytidine- ¹³C is the ¹³C labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine

HY-B0158S3

Cytidine-d2-1
Cytidine-d₂-1 is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catech

HY-B0158S2

Cytidine-13C-1
Cytidine- ¹³C-1 is the ¹³C labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholami

HY-B0158S6

Cytidine-15N3
Cytidine- ¹⁵N₃ is the ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-W744643

Butylphthalide-d9
Butylphthalide-d₉ (3-n-Butylphthalide-d₉) is deuterium labeled Butylphthalide. Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models .

HY-B0158S5

Cytidine-13C9,15N3
Cytidine- ¹³C₉, ¹⁵N₃ is the ¹³C and ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-109502S

10-OH-NBP-d4
10-OH-NBP-d₄ is deuterium labeled 10-OH-NBP. 10-OH-NBP is a Butylphthalide (3-n-Butylphthalide; NBP; HY-B0647) hydroxylated metabolite and can penetrates the blood-brain barrier (BBB). Butylphthalide exerts neuroprotective effects and has potential for cerebral ischemia research[1].

HY-B0158S8

Cytidine-d13
Cytidine-d13 (Cytosine β-D-riboside-d13; Cytosine-1-β-D-ribofuranoside-d13) is deuterium labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-B0158S7

Cytidine-13C9
Cytidine- ¹³C9 (Cytosine β-D-riboside- ¹³C9; Cytosine-1-β-D-ribofuranoside- ¹³C9) is ¹³C labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .

HY-76569S1

(R)-Hydroxytolterodine-d14

(R)-Hydroxytolterodine-d₁₄ is deuterated labeled Desfesoterodine (HY-76569). Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a K_B and a pA₂ of 0.84 nM and 9.14, respectively . Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053) . Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks