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Results for "

isomerase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Phosphomannose Isomerase (PMI) (3) PIN1 (10) Antibiotic (2) Apoptosis (5) Bacterial (4) Biochemical Assay Reagents (12) Carbonic Anhydrase (1) Caspase (1) Cholinesterase (ChE) (1) Cyclophilin (2) Cytochrome P450 (1) Emopamil Binding Protein (1) Endogenous Metabolite (21) FBPase (1) FKBP (1) Fluorescent Dye (1) Fungal (4) HCV (1) Integrin (1) Ligands for Target Protein for PROTAC (1) MicroRNA (1) Mitochondrial Metabolism (2) p38 MAPK (1) PDI (13) Phosphatase (1) Polo-like Kinase (PLK) (1) Reactive Oxygen Species (1) Sigma Receptor (2) STAT (1) Transketolase (1)
By Research Areas:	Cancer (23) Cardiovascular Disease (4) Infection (9) Inflammation/Immunology (3) Metabolic Disease (23) Neurological Disease (6)
Click Chemistry:	Alkynes (2)
Oligonucleotides:	Sweetening Agents (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Phosphomannose Isomerase (PMI) PIN1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-E70308

*Glucose isomerase* (immobilized)**	Endogenous Metabolite	Others
Glucose isomerase (immobilized) is a glucose isomerase that catalyzes the reversible isomerization of D-glucose and D-xylose into D-fructose and D-xylulose, respectively. Glucose isomerase (immobilized) is thermally stable and can be used to produce fructose syrup at high temperatures above 90°C. Glucose isomerase (immobilized) is widely distributed in prokaryotes .

HY-P2918

*Phosphoglucose Isomerase, Rabbit muscle* GPI; Phosphoglucose isomerase	Endogenous Metabolite	Metabolic Disease Cancer
Phosphoglucose Isomerase, Rabbit muscle (GPI), i.e., phosphoglucose isomerase/phosphoglucoisomerase (PGI) or phosphohexose isomerase (PHI), is often used in biochemical studies. Glucose 6-phosphate isomeras is a highly conserved glycolytic and dimeric enzyme. Glucose 6-phosphate isomeras catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .

HY-P2931

Triosephosphate isomerase TPI	Endogenous Metabolite	Others Cancer
Triosephosphate isomerase (TPI) is a glycolytic enzyme. Triosephosphate isomerase fast interconverts dihydroxyacetone phosphate and D: -glyceraldehyde-3-phosphate, its catalytic site is at the dimer interface .

HY-E70120

Phosphomannose isomerase	Fungal	Infection
Phosphomannose isomerase is the first enzyme involved in the biosynthesis pathway of GDP-Man. Phosphomannose isomerase catalyzes the conversion between fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P). Phosphomannose isomerase is important for cell wall synthesis and protein glycosylation. Phosphomannose isomerase is a potent antifungal target to curb the threats posed by A. flavus .

HY-E70022

*D-Mannose isomerase* (PsMaSeAF)**	Others	Others
D-Mannose isomerase (PsMaSeAF) is a carbohydrate isomerase catalyzing the reversible isomerization of d-mannose to d-fructose. D-Mannose isomerase (PsMaSeAF) belongs to the N-acylglucosamine 2-epimerase (AGE) superfamily along with AGE, cellobiose 2-epimerase (CE), and aldose-ketose isomerase (AKI) .

HY-P2918A

*Phosphoglucose isomerase, bacillus stearothermophilus*	Endogenous Metabolite	Metabolic Disease
Phosphoglucose isomerase, bacillus stearothermophilus is a highly conserved glycolytic and dimeric enzyme. Phosphoglucose isomerase, bacillus stearothermophilus catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .

HY-P2918B

*Phosphoglucose isomerase, Baker's Yeast*	Endogenous Metabolite	Metabolic Disease
Phosphoglucose isomerase, bacillus stearothermophilus is a highly conserved glycolytic and dimeric enzyme. Phosphoglucose isomerase, bacillus stearothermophilus catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .

HY-P2930

Peptidylprolyl isomerase	Biochemical Assay Reagents	Others
Peptidylprolyl isomerase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2927

Protein disulfide isomerase	Biochemical Assay Reagents	Others
Protein disulfide isomerase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2886

Ribose-5-phosphate isomerase Phosphoriboisomerase	Biochemical Assay Reagents	Others
Ribose-5-phosphate isomerase (Phosphoriboisomerase) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-E70440

L-Arabinose isomerase	Biochemical Assay Reagents	Others
L-Arabinose isomerase is a transglutaminase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-114086

ML359	PDI	Cardiovascular Disease
ML359 is a potent, selctive and reversible inhibitor of *protein disulfide isomerase* (PDI), with an IC₅₀** of 250 nM. ML359 can prevent thrombus formation in vivo .

HY-148077

Phosphoglycolohydroxamic acid	Bacterial Fungal	Infection
Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area .

HY-P4202

Suc-Ala-Glu-Pro-Phe-pNA Suc-AEPF-pNA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-P4202A

Suc-Ala-Glu-Pro-Phe-pNA TFA Suc-AEPF-pNA TFA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-113514

6-Phosphogluconic acid	Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid is a potent and competitive *phosphoglucose isomerase* (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite** .

HY-W011184

6-Phosphogluconic acid trisodium	Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid trisodium is a potent and competitive *phosphoglucose isomerase* (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite** .

HY-13751

SR-31747	Sigma Receptor	Inflammation/Immunology
SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase .

HY-13751A

SR-31747 free base	Sigma Receptor	Inflammation/Immunology
SR-31747 free base is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase .

HY-124890

Thr101	Phosphomannose Isomerase (PMI)	Metabolic Disease
Thr101 is an inhibitor (IC₅₀=2.9 μM) of phosphomannose isomerase (PMI).PMI can compete with phosphomannose mutase 2 (PMM2) for the binding site of Man-6-P and convert mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) .Thr101 only specifically inhibits PMI and not PMM2. Thr101 can be used for research of congenital disorder of glycosylation type Ia (CDG-Ia) .

HY-P3480

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA	Fluorescent Dye	Others
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .

HY-138802

ML089 1 Publications Verification	Phosphomannose Isomerase (PMI)	Metabolic Disease
ML089 is a potent, selective, and orally available phosphomannose isomerase (PMI) inhibitor with an IC₅₀ of 1.3 µM. ML089 can be used for the research of congenital disorder of glycosylation Ia .

HY-N0537

Xylose 3 Publications Verification D-(+)-Xylose; (+)-Xylose; Wood sugar	Endogenous Metabolite	Metabolic Disease
Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation .

HY-130588A

Glutathione arsenoxide TFA GSAO TFA	Mitochondrial Metabolism	Cancer
Glutathione arsenoxide (GSAO) TFA is a potential anticancer agent and a tumour metabolism inhibitor. Glutathione arsenoxide TFA targets Mitochondrial endomycin nucleotide transferase (ANT). Glutathione arsenoxide TFA causes cell proliferation arrest and cell death. Glutathione arsenoxide TFA can be used to identify cell-surface proteins, such as Protein disulphide isomerase .

HY-100430

CCF642	Apoptosis PDI	Cancer
CCF642 is a potent *protein disulfide isomerases* (PDI) inhibitor with an IC₅₀** of 2.9 μM. CCF642 causes acute endoplasmic reticulum (ER) stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. CCF642 has broad anti-multiple myeloma activity .

HY-107420

AY 9944 3 Publications Verification	Endogenous Metabolite	Metabolic Disease
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme with an IC₅₀ of 13 nM. AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol .

HY-122895

E64FC26 2 Publications Verification	Apoptosis PDI	Cancer
E64FC26 is a potent pan-inhibitor of the *protein disulfide isomerase* (PDI) family, with IC₅₀**s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6, respectively. E64FC26 shows anti-myeloma activity .

HY-122895A

(E/Z)-E64FC26	Apoptosis PDI	Cancer
(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the *protein disulfide isomerase* (PDI) family, with IC₅₀**s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity .

HY-111117

3-Methyltoxoflavin 1 Publications Verification	PDI	Cancer
3-Methyltoxoflavin is a potent *Protein disulfide isomerase* (PDI) inhibitor, with an IC₅₀** of 170 nM.

HY-P4359

Suc-AEPF-AMC	PIN1	Others
Suc-AEPF-AMC is a peptide substrate of Pin1 and Par14 peptidyl prolyl isomerase .

HY-W016508

L-Mannose	Others	Others
L-Mannose is a monosaccharide. L-Mannose can be used as the substrate of mannose-6-phosphate isomerase .

HY-112945

MLS0315771 3 Publications Verification	Phosphomannose Isomerase (PMI)	Metabolic Disease
MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC₅₀ ~1 μM and a K_i of 1.4 μM.

HY-113317

L-Xylulose	Endogenous Metabolite	Cardiovascular Disease
L-Xylulose is an endogenous metabolite present in Blood, Cerebrospinal_Fluid and Urine that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency .

HY-N7386A

D-Erythrose 4-phosphate sodium	Endogenous Metabolite	Metabolic Disease
D-Erythrose 4-phosphate sodium is a phosphate sodium of the simple sugar Erythrose. Erythritol is actually converted into D-Erythrose 4-phosphate that involves three isomerases .

HY-124866

PDI-IN-3	PDI	Neurological Disease
PDI-IN-3 (compound 16F16) is a *protein disulfide isomerase* (PDI)** inhibitor. PDI-IN-3 inhibits cell viability .

HY-170766

PIN1 inhibitor 4	PIN1	Others
PIN1 inhibitor 4 (compound 6a) is a covalent inhibitor of peptidyl-prolyl isomerase Pin1, with IC₅₀=3.15 μM .

HY-W040141

L-Arabinitol	Endogenous Metabolite	Metabolic Disease
L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose-5-phosphate isomerase deficiency.

HY-128592

TAB29	PIN1	Cancer
TAB29 is a potent inhibitor of *peptidyl-prolyl cis-trans isomerase* NIMA-interacting 1 (Pin1) with an IC₅₀** of 874 nM, possesses therapeutic potential for human cancers .

HY-113375

D-Ribofuranose D-Ribose	Endogenous Metabolite	Cardiovascular Disease
D-Ribofuranose (D-Ribose) is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency and Medium Chain Acyl Co A Dehydrogenase Deficiency .

HY-E70430

N-Acylhexosamine oxidase	Biochemical Assay Reagents	Others
N-Acylhexosamine oxidase is an isomerase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-110172

PDI-IN-1	PDI	Cancer
PDI-IN-1 (Compound P1) is a cell-permeable human protein disulfide isomerase (PDI) inhibitor with an IC₅₀ of 1.7 μM. PDI-IN-1 has anti-cancer activity.

HY-113407A

D-Fructose-6-phosphate disodium	Endogenous Metabolite FBPase	Neurological Disease Metabolic Disease
D-Fructose 6-phosphate disodium is an endogenous metabolite. D-Fructose 6-phosphate disodium can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate disodium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate disodium can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia.

HY-N0537R

Xylose (Standard)	Endogenous Metabolite	Others
Xylose (Standard) is the analytical standard of Xylose. This product is intended for research and analytical applications. D-(+)-xylose (Xylose) is a natural compound that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of xylose.

HY-P2734

Phosphorylase a, rabbit muscle	Biochemical Assay Reagents	Others
Phosphopentomutase (EC 5.4.2.7) is an isomerase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-126825

NE21650	Phosphatase	Metabolic Disease
NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro .

HY-167805

D-Glucose 6-phosphate potassium	Biochemical Assay Reagents
D-Glucose 6-phosphate potassium is a biologically active compound that has the activity of being a substrate for glucose-6-phosphate isomerase. D-Glucose 6-phosphate potassium can participate in the sugar metabolism process and promote the production and utilization of energy in cells.

HY-B1228

Ribostamycin sulfate 1 Publications Verification Vistamycin sulfate	Bacterial Antibiotic PDI	Infection
Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies

HY-107193

Bacitracin 1 Publications Verification	Bacterial Antibiotic PDI	Infection Cancer
Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor .

HY-139361

Sulfopin 2 Publications Verification PIN1-3	PIN1	Cancer
Sulfopin (PIN1-3) is a highly selective covalent inhibitor of Pin1 with an apparent K_i of 17 nM. Sulfopin blocks Myc-driven tumors in vivo. The peptidyl-prolyl isomerase, Pin1, is exploited in cancer to activate oncogenes and inactivate tumor suppressors .

HY-116716

PIN1 inhibitor API-1	MicroRNA	Cancer
PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor (API-1) with an IC₅₀ of 72.3 nM. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase (PPIase) domain and potently inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development .

Cat. No.	Product Name

HY-L058

Glycolysis Compound Library

852 compounds

Glycolysis is a series of metabolic processes by which one molecule of glucose is catabolized to two molecules of pyruvate with a net gain of two ATP. Glycolysis takes place in 10 steps and catalyzed by a series of enzyme, such as hexokinase, Glucose-6-phosphate isomerase, Phosphofructokinase, etc. Glycolysis is used by all cells in the body for energy generation.

Most cancer cells exhibit increased glycolysis and use this metabolic pathway for generation of ATP as a main source of their energy supply. This phenomenon is known as the Warburg effect and is considered as one of the most fundamental metabolic alterations during malignant transformation. Because increased aerobic glycolysis is commonly seen in a wide spectrum of human cancers, development of novel glycolytic inhibitors as a new class of anticancer agents is likely to have broad therapeutic applications.

MCE provides a unique collection of 852 glycolysis compounds that mainly target hexokinase, glucokinase, enolase, pyruvate kinase, PDHK, etc. MCE Glycolysis Compound Library is a useful tool for glucose metabolism research and anti-cancer drug discovery.

Cat. No.	Product Name	Type

HY-P4202

Suc-Ala-Glu-Pro-Phe-pNA Suc-AEPF-pNA	Chromogenic Substrates
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-P4202A

Suc-Ala-Glu-Pro-Phe-pNA TFA Suc-AEPF-pNA TFA	Chromogenic Substrates
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

Cat. No.	Product Name	Type

HY-116037

cis-10-Heptadecenoic acid	Biochemical Assay Reagents
cis-10-Heptadecenoic acid is a cis-fatty acid. cis-10-Heptadecenoic acid synthesizes polyhydroxy-chain alkanoates under the action of 2, 4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase .

HY-167805

D-Glucose 6-phosphate potassium	Enzyme Substrates
D-Glucose 6-phosphate potassium is a biologically active compound that has the activity of being a substrate for glucose-6-phosphate isomerase. D-Glucose 6-phosphate potassium can participate in the sugar metabolism process and promote the production and utilization of energy in cells.

HY-W725496

D-Fructose 6-phosphate dipotassium

Carbohydrates

D-Fructose 6-phosphate dipotassium is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase). D-Fructose 6-phosphate dipotassium can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose 6-phosphate dipotassium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate dipotassium can be used to study Lewy body dementia .

Cat. No.	Product Name	Target	Research Area

HY-P4202

Suc-Ala-Glu-Pro-Phe-pNA Suc-AEPF-pNA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-P4359

Suc-AEPF-AMC	PIN1	Others
Suc-AEPF-AMC is a peptide substrate of Pin1 and Par14 peptidyl prolyl isomerase .

HY-P4202A

Suc-Ala-Glu-Pro-Phe-pNA TFA Suc-AEPF-pNA TFA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-P3480

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA	Fluorescent Dye	Others
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .

HY-P4698

Tri-valine NSC 35938	Peptides	Metabolic Disease
Tri-valine (NSC 35938) is a polypeptide that can be separated from Creatine kinase (HY-P2799), β-enolase, Triosephosphate isomerase (HY-P2931) and glyceraldehyde 3-phosphate dehydrogenase .

HY-P10411

BING	Bacterial	Infection
BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .

Species:	Human (45) Mouse (13) Rat (1) E.coli (2)
Tag:	His (54) SUMO (4) Tag Free (12) GST (3) Trx (1) Flag (2) B2M (1) Fc (3) CL7 (1)
Source:	HEK293 (24) P. pastoris (1) Sf9 insect cells (1) E. coli (46)

Cat. No.	Compare	Product Name	Species	Source

HY-P70903

	IDI2 Protein, Human (His) Isopentenyl-Diphosphate Delta-isomerase 2; Isopentenyl Pyrophosphate isomerase 2; IPP isomerase 2; IPPI2; IDI2	Human	E. coli
	IDI2 protein plays a crucial role in catalyzing the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP), leading to the formation of its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). This enzymatic activity is a key step in the biosynthetic pathway, contributing to the generation of essential building blocks for various cellular processes. IDI2 Protein, Human (His) is the recombinant human-derived IDI2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IDI2 Protein, Human (His) is 227 a.a., with molecular weight of 28-31 kDa.

HY-P70903A

	IDI2 Protein, Human (C-His) Isopentenyl-Diphosphate Delta-isomerase 2; Isopentenyl Pyrophosphate isomerase 2; IPP isomerase 2; IPPI2; IDI2	Human	E. coli
	IDI2 protein plays a crucial role in catalyzing the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP), leading to the formation of its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). This enzymatic activity is a key step in the biosynthetic pathway, contributing to the generation of essential building blocks for various cellular processes. IDI2 Protein, Human (C-His) is the recombinant human-derived IDI2 protein, expressed by E. coli , with C-8*His labeled tag. The total length of IDI2 Protein, Human (C-His) is 225 a.a., with molecular weight of ~27 kDa.

HY-P71364

	TIM Protein, Human (His) Triosephosphate isomerase; TIM; Triose-Phosphate isomerase; TPI1; TPI	Human	E. coli
	TIM protein is a highly efficient metabolic enzyme that catalyzes the rapid interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) during glycolysis and gluconeogenesis. Its key role in glucose metabolism is complemented by an additional responsibility: the production of methylglyoxal, a reactive cytotoxic by-product. TIM Protein, Human (His) is the recombinant human-derived TIM protein, expressed by E. coli , with N-6*His labeled tag. The total length of TIM Protein, Human (His) is 249 a.a., with molecular weight of ~30.0 kDa.

HY-P702172

	maiA Protein, Serratia marcescens maiA; Maleate isomerase; Maleate cis-trans isomerase	Others	E. coli
	The maiA protein is a key enzyme involved in catalyzing the cis-trans isomerization of the C2-C3 double bond in maleic acid, leading to the formation of fumaric acid. By facilitating this chemical transformation, maiA plays a crucial role in regulating the isomeric configuration of the C2-C3 double bond in maleic acid, ultimately converting it into fumaric acid. maiA Protein, Serratia marcescens is the recombinant maiA protein, expressed by E. coli , with tag free. The total length of maiA Protein, Serratia marcescens is 250 a.a., .

HY-P701942

	*L-arabinose isomerase* Protein, Bacillus subtilis** araA; L-arabinose isomerase	Others	E. coli
	L-arabinose isomerase is a key enzyme in carbohydrate metabolism and plays a key role in catalyzing the conversion of L-arabinose to L-ribulose. This enzymatic activity is part of a broader biochemical pathway involved in the interconversion of sugars. L-arabinose isomerase Protein, Bacillus subtilis is the recombinant L-arabinose isomerase protein, expressed by E. coli , with tag free. The total length of L-arabinose isomerase Protein, Bacillus subtilis is 496 a.a., .

HY-P701943

	*L-arabinose isomerase* Protein, Bacillus subtilis (His)** araA; L-arabinose isomerase	Others	E. coli
	L-arabinose isomerase is a key enzyme in carbohydrate metabolism and plays a key role in catalyzing the conversion of L-arabinose to L-ribulose. This enzymatic activity is part of a broader biochemical pathway involved in the interconversion of sugars. L-arabinose isomerase Protein, Bacillus subtilis (His) is the recombinant L-arabinose isomerase protein, expressed by E. coli , with N-6*His labeled tag. The total length of L-arabinose isomerase Protein, Bacillus subtilis (His) is 496 a.a., .

HY-P702173

	maiA Protein, Serratia marcescens (FLAG, His) maiA; Maleate isomerase; Maleate cis-trans isomerase	Others	E. coli
	The maiA protein is a key enzyme involved in catalyzing the cis-trans isomerization of the C2-C3 double bond in maleic acid, leading to the formation of fumaric acid. By facilitating this chemical transformation, maiA plays a crucial role in regulating the isomeric configuration of the C2-C3 double bond in maleic acid, ultimately converting it into fumaric acid. maiA Protein, Serratia marcescens (FLAG, His) is the recombinant maiA protein, expressed by E. coli , with N-6*His, N-Flag labeled tag. The total length of maiA Protein, Serratia marcescens (FLAG, His) is 250 a.a., .

HY-P702109

	dai Protein, Aeribacillus pallidus dai; L-fucose isomerase; FucIase; 6-deoxy-L-galactose isomerase	Others	E. coli
	Dai protein serves as a catalyst in the biochemical conversion of the aldose L-fucose into its corresponding ketose, L-fuculose. This enzymatic activity highlights Dai's role in facilitating the transformation of specific sugar molecules, contributing to the diverse metabolic pathways where such conversions play essential roles. dai Protein, Aeribacillus pallidus is the recombinant dai protein, expressed by E. coli , with tag free. The total length of dai Protein, Aeribacillus pallidus is 595 a.a., .

HY-P72210

	*Glucose-6-phosphate isomerase* Protein, Mouse (His-B2M)** Gpi; Gpi1Glucose-6-phosphate isomerase; GPI; EC 5.3.1.9; Autocrine motility factor; AMF; Neuroleukin; NLK; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI	Mouse	E. coli
	Glucose-6-phosphate isomerase protein exists in the cytoplasm and has dual functions. It converts glucose-6-phosphate into fructose-6-phosphate, playing a vital role in glycolysis and gluconeogenesis. Glucose-6-phosphate isomerase Protein, Mouse (His-B2M) is the recombinant mouse-derived Glucose-6-phosphate isomerase protein, expressed by E. coli , with N-6*His, B2M labeled tag. The total length of Glucose-6-phosphate isomerase Protein, Mouse (His-B2M) is 557 a.a., with molecular weight of ~76.6 kDa.

HY-P702110

	dai Protein, Aeribacillus pallidus (FLAG, His) dai; L-fucose isomerase; FucIase; 6-deoxy-L-galactose isomerase	Others	E. coli
	Dai protein serves as a catalyst in the biochemical conversion of the aldose L-fucose into its corresponding ketose, L-fuculose. This enzymatic activity highlights Dai's role in facilitating the transformation of specific sugar molecules, contributing to the diverse metabolic pathways where such conversions play essential roles. dai Protein, Aeribacillus pallidus (FLAG, His) is the recombinant dai protein, expressed by E. coli , with N-6*His, N-Flag labeled tag. The total length of dai Protein, Aeribacillus pallidus (FLAG, His) is 595 a.a., .

HY-P70206A

	*Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His)* rHuMaleylacetoacetate isomerase/GSTZ1, His; Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-Transferase Zeta 1; GSTZ1	Human	E. coli
	The maleylacetoacetate isomerase/GSTZ1 protein is a member of the GST superfamily and detoxifies electrophilic molecules. It converts maleylacetoacetate to fumarylacetoacetate, a key step in phenylalanine/tyrosine degradation. Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His) is the recombinant human-derived Maleylacetoacetate isomerase/GSTZ1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His) is 215 a.a., with molecular weight of ~25 kDa.

HY-P71738

	*Glucose-6-phosphate isomerase* Protein, Mouse (P.pastoris, His)** Gpi; Gpi1Glucose-6-phosphate isomerase; GPI; AMF; Neuroleukin; NLK; PHI	Mouse	P. pastoris
	Glucose-6-phosphate isomerase protein exists in the cytoplasm and has dual functions. It converts glucose-6-phosphate into fructose-6-phosphate, playing a vital role in glycolysis and gluconeogenesis. Glucose-6-phosphate isomerase Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Glucose-6-phosphate isomerase protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P702151

	araA Protein, Anoxybacillus flavithermus araA; L-arabinose isomerase	Others	E. coli
	The araA protein plays a crucial role in cellular metabolism by catalyzing the conversion of L-arabinose into L-ribulose. This enzymatic activity is an integral part of the broader biochemical pathways that control the interconversion of sugars. araA Protein, Anoxybacillus flavithermus is the recombinant araA protein, expressed by E. coli , with tag free. The total length of araA Protein, Anoxybacillus flavithermus is 496 a.a., .

HY-P71192

	PDIA5 Protein, Human (HEK293, His) Protein disulfide-isomerase A5; Protein disulfide isomerase-related protein; PDIA5; PDIR	Human	HEK293
	PDIA5 Protein catalyzes the rearrangement of disulfide bonds in proteins, ensuring proper folding and stabilization. Its vital role maintains protein structure and function, guaranteeing effective performance of designated biological tasks through correct disulfide bond formation. PDIA5 Protein, Human (HEK293, His) is the recombinant human-derived PDIA5 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PDIA5 Protein, Human (HEK293, His) is 241 a.a., with molecular weight of ~30 kDa.

HY-P701901

	GNPDA2 Protein, Human GNPDA2; Glucosamine-6-phosphate isomerase 2; Glucosamine-6-phosphate deaminase 2; GNPDA 2; GlcN6P deaminase 2; Glucosamine-6-phosphate isomerase SB52	Human	E. coli
	The GNPDA2 protein catalyzes the reversible conversion of α-D-glucosamine 6-phosphate to β-D-fructose 6-phosphate and ammonium ions, which is a key step in de novo UDP-GlcNAc biosynthesis. GNPDA2 Protein, Human is the recombinant human-derived GNPDA2 protein, expressed by E. coli , with tag free. The total length of GNPDA2 Protein, Human is 275 a.a., .

HY-P702152

	araA Protein, Geobacillus stearothermophilus (His) araA; L-arabinose isomerase	Others	E. coli
	araA protein, a key component, facilitates the conversion of L-arabinose to L-ribulose. Furthermore, in vitro experiments reveal its capability to convert D-galactose to D-tagatose. araA Protein, Geobacillus stearothermophilus (His) is the recombinant araA protein, expressed by E. coli , with N-6*His labeled tag. The total length of araA Protein, Geobacillus stearothermophilus (His) is 496 a.a., .

HY-P701902

	GNPDA2 Protein, Human (His) GNPDA2; Glucosamine-6-phosphate isomerase 2; Glucosamine-6-phosphate deaminase 2; GNPDA 2; GlcN6P deaminase 2; Glucosamine-6-phosphate isomerase SB52	Human	E. coli
	The GNPDA2 protein catalyzes the reversible conversion of α-D-glucosamine 6-phosphate to β-D-fructose 6-phosphate and ammonium ions, which is a key step in de novo UDP-GlcNAc biosynthesis. GNPDA2 Protein, Human (His) is the recombinant human-derived GNPDA2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GNPDA2 Protein, Human (His) is 275 a.a., .

HY-P70047

	*Peptidyl-prolyl cis-trans isomerase* A/CYPA Protein, Human** rHuPeptidyl-prolyl cis-trans isomerase A/CYPA; Peptidyl-prolyl cis-trans isomerase A; PPIase A; Cyclophilin A; Cyclosporin A-binding protein; Rotamase A; SP18; PPIA; CYPA	Human	E. coli
	CYPA protein, a peptidyl prolyl cis-trans isomerase, has proinflammatory activity by stimulating activation of NF-kappa-B and ERK, JNK, and p38 MAP kinases. It may act as a mediator between the human SARS coronavirus nucleoprotein and BSG/CD147 during the virus' invasion of host cells. Peptidyl-prolyl cis-trans isomerase A/CYPA Protein, Human is the recombinant human-derived Peptidyl-prolyl cis-trans isomerase A/CYPA protein, expressed by E. coli , with tag free.

HY-P71226

	PPIL1 Protein, Human (His) Peptidyl-Prolyl Cis-Trans isomerase-Like 1; PPIase; Rotamase PPIL1; PPIL1; CYPL1	Human	E. coli
	The PPIL1 protein is a spliceosome component that coordinates pre-mRNA splicing and controls RNA processing. As a peptidylprolyl cis-trans isomerase (PPIase), PPIL1 accelerates protein folding by catalyzing the cis-trans isomerization of proline imide peptide bonds. PPIL1 Protein, Human (His) is the recombinant human-derived PPIL1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PPIL1 Protein, Human (His) is 166 a.a., with molecular weight of ~19-24 kDa.

HY-P71205

	PIN4 Protein, Human (His) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; Parvulin-14; Parvulin-17; Peptidyl-prolyl cis-trans isomerase Pin4; Peptidyl-prolyl cis/trans isomerase EPVH; Rotamase Pin4; PIN4;	Human	E. coli
	PIN4 isoform 1 functions as a ribosomal RNA processing factor in ribosome biogenesis and interacts with tightly bent AT-rich stretches of double-stranded DNA. Meanwhile, PIN4 isoform 2 specifically binds to double-stranded DNA. PIN4 Protein, Human (His) is the recombinant human-derived PIN4 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PIN4 Protein, Human (His) is 156 a.a., with molecular weight of ~18.0 kDa.

HY-P70047A

	*Peptidyl-prolyl cis-trans isomerase* A/CYPA Protein, Human (Tag Free)** rHuPeptidyl-prolyl cis-trans isomerase A/CYPA; Peptidyl-prolyl cis-trans isomerase A; PPIase A; Cyclophilin A; Cyclosporin A-binding protein; Rotamase A; SP18; PPIA; CYPA	Human	E. coli
	CYPA protein, a peptidyl prolyl cis-trans isomerase, has proinflammatory activity by stimulating activation of NF-kappa-B and ERK, JNK, and p38 MAP kinases. It may act as a mediator between the human SARS coronavirus nucleoprotein and BSG/CD147 during the virus' invasion of host cells. Peptidyl-prolyl cis-trans isomerase A/CYPA Protein, Human is the recombinant human-derived Peptidyl-prolyl cis-trans isomerase A/CYPA protein, expressed by E. coli , with tag free.

HY-P702153

	araA Protein, Anoxybacillus flavithermus (His, CL7) araA; L-arabinose isomerase	Others	E. coli
	The araA protein plays a crucial role in cellular metabolism by catalyzing the conversion of L-arabinose into L-ribulose. This enzymatic activity is an integral part of the broader biochemical pathways that control the interconversion of sugars. araA Protein, Anoxybacillus flavithermus (His, CL7) is the recombinant araA protein, expressed by E. coli , with N-6*His, N-CL7 labeled tag. The total length of araA Protein, Anoxybacillus flavithermus (His, CL7) is 496 a.a., .

HY-P70059

	ECH1 Protein, Human (His) 1 Publications Verification rHuDelta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial/ECH1, His; Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase; mitochondrial; ECH1;	Human	E. coli
	ECH1 Protein plays a crucial role in isomerization, converting 3-trans,5-cis-dienoyl-CoA to its isomeric form, 2-trans,4-trans-dienoyl-CoA. This enzymatic step is vital in metabolic pathways, ensuring the equilibrium of dienoyl-CoA species and contributing to overall metabolic flux. ECH1's activity is essential for maintaining structural rearrangement in Coenzyme A (CoA)-linked intermediates, emphasizing its significance in cellular processes. ECH1 Protein, Human (His) is the recombinant human-derived ECH1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ECH1 Protein, Human (His) is 295 a.a., with molecular weight of 30-35 kDa.

HY-P70007A

	Cyclophilin A Protein, Mouse 1 Publications Verification rMuPeptidyl-prolyl cis-trans isomerase A/Cyclophilin A; Peptidyl-prolyl cis-trans isomerase A; PPIase A; Cyclophilin A; Cyclosporin A-binding protein; Rotamase A; SP18; PPIA; CYPA	Mouse	E. coli
	Cyclophilin A protein catalyzes the isomerization of proline imide peptide bonds in oligopeptides. Cyclophilin A Protein, Mouse is the recombinant mouse-derived Cyclophilin A protein, expressed by E. coli , with tag free.

HY-P71224A

	PPID Protein, Human (His) Peptidyl-Prolyl Cis-Trans isomerase D; PPIase D; 40 kDa Peptidyl-Prolyl Cis-Trans isomerase; Cyclophilin-40; CYP-40; Cyclophilin-Related Protein; Rotamase D; PPID; CYP40; CYPD	Human	E. coli
	PPID protein is a peptidyl prolyl cis-trans isomerase (PPIase) that catalyzes the isomerization of prolyl imide peptide bonds and contributes to protein folding. It serves as a co-chaperone in the HSP90 complex, contributing to dynamic regulation and may favor the estrogen receptor complex. PPID Protein, Human (His) is the recombinant human-derived PPID protein, expressed by E. coli , with N-6His, C-6His labeled tag.

HY-P72168

	DCT Protein, Human (His-SUMO) L dopachrome tautomerase; DCT; Dopachrome delta isomerase; Dopachrome tautomerase; Dopachrome tautomerase dopachrome delta isomerase; tyrosine related protein 2; DT; EC 5.3.3.12; L dopachrome Delta isomerase; L-dopachrome Delta-isomerase; L-dopachrome tautomerase; TRP 2; TRP-2; TRP2; Tyrosinase related protein 2; Tyrosinase-related protein 2; TYRP2; TYRP2_HUMAN	Human	E. coli
	DCT Protein is essential in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a pivotal step in melanin synthesis. DCT Protein, Human (His-SUMO) is the recombinant human-derived DCT protein, expressed by E. coli , with N-SUMO, N-10*His labeled tag. The total length of DCT Protein, Human (His-SUMO) is 449 a.a., with molecular weight of ~71.3 kDa.

HY-P70007

	Cyclophilin A Protein, Mouse (solution) rMuPeptidyl-prolyl cis-trans isomerase A/Cyclophilin A; Peptidyl-prolyl cis-trans isomerase A; PPIase A; Cyclophilin A; Cyclosporin A-binding protein; Rotamase A; SP18; PPIA; CYPA	Mouse	E. coli
	Cyclophilin A protein catalyzes the isomerization of proline imide peptide bonds in oligopeptides. Cyclophilin A Protein, Mouse (solution) is the recombinant mouse-derived Cyclophilin A protein, expressed by E. coli , with tag free. The total length of Cyclophilin A Protein, Mouse is 164 a.a., with molecular weight of ~17.0 kDa.

HY-P71224

	PPID Protein, Human (His, solution) 1 Publications Verification Peptidyl-Prolyl Cis-Trans isomerase D; PPIase D; 40 kDa Peptidyl-Prolyl Cis-Trans isomerase; Cyclophilin-40; CYP-40; Cyclophilin-Related Protein; Rotamase D; PPID; CYP40; CYPD	Human	E. coli
	PPID protein is a peptidyl prolyl cis-trans isomerase (PPIase) that catalyzes the isomerization of prolyl imide peptide bonds and contributes to protein folding. It serves as a co-chaperone in the HSP90 complex, contributing to dynamic regulation and may favor the estrogen receptor complex. PPID Protein, Human (His, solution) is the recombinant human-derived PPID protein, expressed by E. coli , with N-6His, C-6His labeled tag.

HY-P71194

	PDILT Protein, Human (HEK293, His) Protein Disulfide-isomerase-Like Protein of the Testis; PDILT	Human	HEK293
	The PDILT protein is a possible redox-inactive chaperone essential in spermatogenesis, forming non-disulfide-linked homodimers. Its role emphasizes its importance in male germ cell development. PDILT Protein, Human (HEK293, His) is the recombinant human-derived PDILT protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PDILT Protein, Human (HEK293, His) is 564 a.a., with molecular weight of ~92.0 kDa.

HY-P74211A

	Cyclophilin F/PPIF Protein, Human (HEK293, His) Peptidyl-prolyl cis-trans isomerase; PPIase; PPIF	Human	HEK293
	Cyclophilin F/PPIF protein is a peptidyl prolyl cis-trans isomerase (PPIase) that catalyzes the isomerization of proline imide peptide bonds and may contribute to protein folding. It critically regulates the mitochondrial permeability transition pore (mPTP), affecting cell apoptosis or necrosis. Cyclophilin F/PPIF Protein, Human (HEK293, His) is the recombinant human-derived Cyclophilin F/PPIF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Cyclophilin F/PPIF Protein, Human (HEK293, His) is 178 a.a., with molecular weight of ~24-34 kDa.

HY-P74211

	Cyclophilin F/PPIF Protein, Human (HEK293, His, solution) Peptidyl-prolyl cis-trans isomerase; PPIase; PPIF	Human	HEK293
	Cyclophilin F/PPIF protein is a peptidyl prolyl cis-trans isomerase (PPIase) that catalyzes the isomerization of proline imide peptide bonds and may contribute to protein folding. It critically regulates the mitochondrial permeability transition pore (mPTP), affecting cell apoptosis or necrosis. Cyclophilin F/PPIF Protein, Human (HEK293, His, solution) is the recombinant human-derived Cyclophilin F/PPIF protein, expressed by HEK293 , with C-His labeled tag. The total length of Cyclophilin F/PPIF Protein, Human (HEK293, His, solution) is 178 a.a., with molecular weight of ~20.3 kDa.

HY-P74212

	Cyclophilin A Protein, Mouse (His) Peptidyl-prolyl cis-trans isomerase A; PPIase A; SP18; PPIA; CYPA	Mouse	E. coli
	Cyclophilin A (PPIA) protein, with integrin binding and peptidyl-prolyl cis-trans isomerase activity, influences platelet aggregation and neuron differentiation. It is found in the extracellular space and myelin sheath, showing ubiquitous expression in various tissues, including the liver and central nervous system. PPIA is associated with cholangiocarcinoma and HIV disease, suggesting its role in fundamental cellular processes. Cyclophilin A Protein, Mouse (His) is the recombinant mouse-derived Cyclophilin A protein, expressed by E. coli , with C-His labeled tag.

HY-P700388

	HP-0175 Protein, Helicobacter pylori (GST) Rotamase HP_0175; Putative peptidyl-prolyl cis-trans isomerase HP_0175	Others	E. coli
	HP-0175 is an antigen secreted by Helicobacter pylori. HP-0175 provides a link between helicobacter pylori-associated inflammation and gastric cancer by promoting the pro-inflammatory low-cytotoxic TIL response, stromal degradation, and pro-angiogenesis pathways. HP-0175 relies on the unfolded protein response (UPR) to autophagy in gastric epithelial cells and induce apoptosis. HP-0175 Protein, Helicobacter pylori (GST) is the recombinant HP-0175 protein, expressed by E. coli , with N-GST labeled tag. The total length of HP-0175 Protein, Helicobacter pylori (GST) is 278 a.a., with molecular weight of 58.8 kDa.

HY-P71680

	*Glucose-6-phosphate isomerase* Protein, Human (His)** AMF; Aurocrine motility factor; Autocrine motility factor; DKFZp686C13233; EC 5.3.1.9; Neuroleukin; NLK; Oxoisomerase; PGI; PHI; Phosphoglucose isomerase; SA-36; SA36; Sperm antigen 36	Human	E. coli
	Glucose-6-phosphate isomerase protein is a key player in glycolysis, catalyzing the conversion of glucose-6-phosphate into fructose-6-phosphate in the cytoplasm. It carries out this reaction reversibly during gluconeogenesis. Glucose-6-phosphate isomerase Protein, Human (His) is the recombinant human-derived Glucose-6-phosphate isomerase protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71223

	PPIC Protein, Human (Trx-His) Peptidyl-Prolyl Cis-Trans isomerase C; PPIase C; Cyclophilin C; Rotamase C; PPIC; CYPC	Human	E. coli
	PPIC protein is a peptidyl-prolyl cis-trans isomerase (PPIase) that actively catalyzes the cis-trans isomerization of prolyl imide peptide bonds, which is a key step in protein folding. Its role in promoting conformational changes ensures correct folding and maturation of proteins, contributing to cellular proteostasis. PPIC Protein, Human (Trx-His) is the recombinant human-derived PPIC protein, expressed by E. coli , with N-Trx, N-6*His labeled tag. The total length of PPIC Protein, Human (Trx-His) is 152 a.a., with molecular weight of ~34.0 kDa.

HY-P73709

	PGD2 Synthase/PTGDS Protein, Rat (HEK293, His) Prostaglandin-H2 D-isomerase; L-PGDS; PGDS2; PTGDS	Rat	HEK293
	The PGD2 synthase/PTGDS protein converts PGH2 to PGD2, which regulates smooth muscle and inhibits platelet aggregation.It affects central nervous system functions including sedation, NREM sleep, and potential anti-apoptotic effects on oligodendrocytes.PGD2 Synthase/PTGDS Protein, Rat (HEK293, His) is the recombinant rat-derived PGD2 Synthase/PTGDS protein, expressed by HEK293 , with C-His, C-6*His labeled tag.

HY-P73710

	PGD2 Synthase/PTGDS Protein, Mouse (HEK293, His) Prostaglandin-H2 D-isomerase; L-PGDS; PGDS2; PTGDS	Mouse	HEK293
	PGD2 Synthase/PTGDS Protein, an enzyme, is involved in the synthesis of prostaglandin D2 (PGD2). Dysregulation of PGD2 Synthase/PTGDS Protein has been linked to allergic diseases and inflammation. Targeting PGD2 Synthase/PTGDS Protein may provide potential therapeutic interventions in these conditions by modulating PGD2 levels, reducing allergic responses, and managing inflammation-related disorders. PGD2 Synthase/PTGDS Protein, Mouse (HEK293, His) is the recombinant mouse-derived PGD2 Synthase/PTGDS protein, expressed by HEK293 , with C-His labeled tag.

HY-P76546

	PIN1 Protein, Human Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Rotamase Pin1; PIN1	Human	E. coli
	The PIN1 protein is a peptidyl-prolyl cis/trans isomerase that complexly regulates multiple cellular processes by binding and isomerizing phosphorylated Ser/Thr-Pro motifs. This molecular switch induces conformational changes in phosphorylated proteins that affect mitosis, kinase activity, oncogene transactivation, centrosome amplification, and cell transformation. PIN1 Protein, Human is the recombinant human-derived PIN1 protein, expressed by E. coli , with tag free. The total length of PIN1 Protein, Human is 163 a.a., with molecular weight of ~18 kDa.

HY-P71193

	PDIA6 Protein, Human (HEK293, His) Protein Disulfide-isomerase A6; Endoplasmic Reticulum Protein 5; ER Protein 5; ERp5; Protein Disulfide isomerase P5; Thioredoxin Domain-Containing Protein 7; PDIA6; ERP5; P5; TXNDC7	Human	HEK293
	PDIA6 protein has molecular chaperone activity, which can inhibit the aggregation of misfolded proteins and contribute to quality control. It negatively regulates the unfolded protein response (UPR) by binding to ERN1 and inhibiting its signaling. PDIA6 Protein, Human (HEK293, His) is the recombinant human-derived PDIA6 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PDIA6 Protein, Human (HEK293, His) is 421 a.a., with molecular weight of ~52.0 kDa.

HY-P72169

	DCT Protein, Mouse (His-SUMO) Dct; Tyrp-2; Tyrp2; L-dopachrome tautomerase; DCT; DT; EC 5.3.3.12; DOPAchrome conversion factor; DOPAchrome isomerase; DOPAchrome oxidoreductase; L-dopachrome Delta-isomerase; SLATY locus protein; Tyrosinase-related protein 2; TRP-2; TRP2	Mouse	E. coli
	DCT (Dopachrome tautomerase) is pivotal in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a critical step in melanin synthesis. DCT's enzymatic activity is integral to the complex processes governing melanin production, emphasizing its role in skin pigmentation and the regulation of melanin-related functions. DCT Protein, Mouse (His-SUMO) is the recombinant mouse-derived DCT protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag. The total length of DCT Protein, Mouse (His-SUMO) is 449 a.a., with molecular weight of ~69.7 kDa.

HY-P71225

	PPIE Protein, Human (His) Peptidyl-Prolyl Cis-Trans isomerase E; PPIase E; Cyclophilin E; Cyclophilin-33; Rotamase E; PPIE; CYP33	Human	E. coli
	The PPIE protein is a key spliceosome component that complexly regulates pre-mRNA splicing through RNA binding and PPIase activity. It prefers single-stranded RNA with polyA and polyU stretches, indicating an affinity for the poly(A) region of the 3'-UTR. PPIE Protein, Human (His) is the recombinant human-derived PPIE protein, expressed by E. coli , with N-6*His labeled tag. The total length of PPIE Protein, Human (His) is 301 a.a., with molecular weight of ~34.0 kDa.

HY-P74658

	P4HB Protein, Mouse (HEK293, His) Protein disulfide-isomerase; PDI; ERp59; p55; P4HB; Pdia1	Mouse	HEK293
	P4HB proteins are versatile and multifunctional, coordinating disulfide bond catalysis at the cell surface and inside the cell.It exhibits reductase activity, cleaves disulfide bonds, induces structural modifications, and functions as a chaperone to inhibit aggregation of misfolded proteins.P4HB Protein, Mouse (HEK293, His) is the recombinant mouse-derived P4HB protein, expressed by HEK293 , with C-His labeled tag.

HY-P76931

	FKBP14 Protein, Human (HEK293, His) Peptidyl-prolyl cis-trans isomerase FKBP14; 22 kDa FKBP; FKBP-22; FKBP-14	Human	HEK293
	The FKBP14 protein is a peptidyl prolyl cis-trans isomerase (PPIase) that uniquely accelerates protein folding, particularly in protein synthesis. FKBP14 particularly favors 4-hydroxyproline-modified substrates, exhibits significant affinity for type III collagen, and has potential effects on type VI and type X collagen. FKBP14 Protein, Human (HEK293, His) is the recombinant human-derived FKBP14 protein, expressed by HEK293 , with C-His labeled tag. The total length of FKBP14 Protein, Human (HEK293, His) is 188 a.a., with molecular weight of ~25 & 27 kDa, respectively.

HY-P71036

	HPGDS Protein, Human Glutathione-Dependent PGD Synthase; Glutathione-Requiring Prostaglandin D Synthase; Prostaglandin-H2 D-isomerase; HPGDS; GSTS; PGDS; PTGDS2	Human	E. coli
	HPGDS protein is a multifunctional enzyme with bifunctionality, and its C-terminal and N-terminal domains have different activities.The C terminus acts as an epoxide hydrolase, promoting xenobiotic metabolism by degrading harmful epoxides and regulating physiological mediator levels.HPGDS Protein, Human is the recombinant human-derived HPGDS protein, expressed by E.coli , with tag free.

HY-P76344

	FKBP11 Protein, Human (HEK293, Fc) Peptidyl-prolyl cis-trans isomerase FKBP11; PPIase FKBP11; FKBP-19; Rotamase; FKBP-11	Human	HEK293
	The FKBP11 protein is a peptidyl prolyl cis-trans isomerase (PPIase) that plays a crucial role in accelerating protein folding, especially in complex protein synthesis. FKBP11 uses its enzymatic abilities to promote rapid and precise conformational changes that are critical for correct protein folding and maturation. FKBP11 Protein, Human (HEK293, Fc) is the recombinant human-derived FKBP11 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of FKBP11 Protein, Human (HEK293, Fc) is 128 a.a., with molecular weight of ~40.4-45 KDa.

HY-P76345

	FKBP12 Protein, Human (His) Peptidyl-prolyl cis-trans isomerase FKBP1A; FKBP-12; Calstabin-1; FKBP-1A; FKBP1	Human	E. coli
	FKBP12 protein maintains TGFBR1 in an inactive state, inhibits activin signaling by recruiting SMAD7, and modulates RYR1 calcium channel activity. As a PPIase, it speeds up protein folding. FKBP12's multifunctionality underscores its regulatory role in cellular processes, emphasizing its importance in signaling and protein folding. FKBP12 Protein, Human (His) is the recombinant human-derived FKBP12 protein, expressed by E. coli , with C-His labeled tag.

HY-P76346

	FKBP12 Protein, Mouse (His) Peptidyl-prolyl cis-trans isomerase FKBP1A; FKBP-12; Calstabin-1; FKBP-1A; FKBP1	Mouse	E. coli
	The FKBP12 protein is multifunctional and critical in TGF-β signaling by maintaining TGFBR1 in an inactive conformation, thereby preventing receptor activation in the absence of ligand. It recruits SMAD7 to ACVR1B, blocks the binding of SMAD2 and SMAD3 to the activin receptor complex, and thereby inhibits activin signaling. FKBP12 Protein, Mouse (His) is the recombinant mouse-derived FKBP12 protein, expressed by E. coli , with N-His labeled tag. The total length of FKBP12 Protein, Mouse (His) is 107 a.a., with molecular weight of ~13 KDa.

HY-P700792

	MIF Protein, Human (HEK293, His) GIF; L-dopachrome isomerase; GLIF; MMIF; EC 5.3.2.1; EC 5.3.3.12	Human	HEK293
	The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF counteracts the anti-inflammatory effects of glucocorticoids. Although MIF exhibits tautomerase activity in vitro, its physiological substrates remain unknown, and the relevance of this activity to its cytokine function is unclear. MIF Protein, Human (HEK293, His) is the recombinant human-derived MIF protein, expressed by HEK293, with C-His labeled tag. The total length of MIF Protein, Human (HEK293, His) is 114 a.a., with molecular weight of 25-30 kDa.

HY-P76285

	CRELD1 Protein, Human (HEK293, His) Protein disulfide isomerase CRELD1; Cysteine-rich with EGF-like domain protein 1; CIRRIN	Human	HEK293
	CRELD1 Protein, acting as a protein disulfide isomerase, aids in the correct folding and assembly of proteins, crucial for cellular homeostasis. It also contributes to the proper localization of acetylcholine receptors (AChRs) to the plasma membrane, emphasizing its significance in maintaining protein structure and membrane receptor distribution. CRELD1 Protein, Human (HEK293, His) is the recombinant human-derived CRELD1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76286

	CRELD1 Protein, Mouse (HEK293, Fc) Protein disulfide isomerase CRELD1; Cysteine-rich with EGF-like domain protein 1; CIRRIN	Mouse	HEK293
	The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-hFc labeled tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82032

	AMF Antibody (YA1777) GPI; Glucose-6-phosphate isomerase; GPI; Autocrine motility factor; AMF; Neuroleukin; NLK; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Sperm antigen 36; SA-36	WB, IHC-P, ICC/IF, FC	Human
	AMF Antibody (YA1777) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1777), targeting AMF, with a predicted molecular weight of 63 kDa (observed band size: 63 kDa). AMF Antibody (YA1777) can be used for WB, IHC-P, ICC/IF, FC experiment in human background.

HY-P81196

	HSD3B1 Antibody 3BHS1_HUMAN; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase 1; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase 1; EC:1.1.1.145; 3-beta-hydroxysteroid 3-dehydrogenase 1; EC:1.1.1.270; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase. EC:1.1.1.210; Steroid Delta-isomerase 1; EC:5.3.3.1; Trophoblast antigen FDO161G; 3BH; HSDB3A;	WB, ICC/IF	Human
	HSD3B1 Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-HSD3B1 monoclonal antibody. HSD3B1 Antibody can be used for: WB,ICC/IF expriments in human background without labeling.

HY-P82167

	MIF Antibody (YA1912) MIF; GLIF; MMIF; Macrophage migration inhibitory factor; MIF; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; Phenylpyruvate tautomerase	WB, IP, FC	Human, Mouse, Rat
	MIF Antibody (YA1912) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1912), targeting MIF, with a predicted molecular weight of 12 kDa (observed band size: 13 kDa). MIF Antibody (YA1912) can be used for WB, IP, FC experiment in human, mouse, rat background.

HY-P80638

	Cyclophilin B Antibody (YA787) PPIB; CYPB; Peptidyl-prolyl cis-trans isomerase B; PPIase B; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP	WB, IHC-P	Human, Rat, Mouse
	Cyclophilin B Antibody (YA787) is a non-conjugated and Mouse origined monoclonal antibody about 24 kDa, targeting to Cyclophilin B (5F10). It can be used for WB,IHC-P assays with tag free, in the background of Human, Rat, Mouse.

HY-P82913

	DCI Antibody (YA2658) ECI1; DCI; Enoyl-CoA delta isomerase 1; mitochondrial; 3; 2-trans-enoyl-CoA isomerase; Delta(3); Delta(2)-enoyl-CoA isomerase; D3; D2-enoyl-CoA isomerase; Dodecenoyl-CoA isomerase	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	DCI Antibody (YA2658) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2658), targeting DCI, with a predicted molecular weight of 33 kDa (observed band size: 33 kDa). DCI Antibody (YA2658) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, mouse, rat background.

HY-P81340

	*Mannose Phosphate Isomerase* Antibody (YA1085)** PMI; PMI1; CDG1B	WB, ICC/IF	Human, Rat
	Mannose Phosphate Isomerase Antibody (YA1085) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1085), targeting Mannose Phosphate Isomerase, with a predicted molecular weight of 47 kDa (observed band size: 47 kDa). Mannose Phosphate Isomerase Antibody (YA1085) can be used for WB, ICC/IF experiment in human, rat background.

HY-P82321

	*Triosephosphate Isomerase* Antibody (YA2066)** HEL-S-49; TIM; TPI1; TPID	WB, FC	Human, Mouse, Rat
	Triosephosphate Isomerase Antibody (YA2066) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2066), targeting Triosephosphate Isomerase, with a predicted molecular weight of 27 kDa (observed band size: 27 kDa). Triosephosphate Isomerase Antibody (YA2066) can be used for WB, FC experiment in human, mouse, rat background.

HY-P82857

	Cyclophilin F Antibody (YA2602) PPIF; CYP3; Peptidyl-prolyl cis-trans isomerase F; mitochondrial; PPIase F; Cyclophilin F; Rotamase F	WB, IHC-P	Human, Mouse, Rat
	Cyclophilin F Antibody (YA2602) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2602), targeting Cyclophilin F, with a predicted molecular weight of 22 kDa (observed band size: 18 kDa). Cyclophilin F Antibody (YA2602) can be used for WB, IHC-P experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-100433

PACMA 31		Alkynes
PACMA 31 is an irreversible, orally active *protein disulfide isomerase* (PDI) inhibitor with an IC₅₀** of 10 μM. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues . PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-117570

KSC-34		Alkynes
KSC-34, a covalent modifier of *protein disulfide isomerase* A1 (PDIA1), is also a selective and potent a-site inhibitor of PDIA1 with an IC₅₀** of 3.5 μM. KSC-34 displays a 30-fold selectivity for a domain over a′ domain and displays high selectivity for PDIA1 in complex proteomes with minimal engagement of other members of the PDI family . KSC-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-N0537

Xylose 3 Publications Verification D-(+)-Xylose; (+)-Xylose; Wood sugar		Sweetening Agents
Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation .

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