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Respiratory

" in MedChemExpress (MCE) Product Catalog:

376

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2

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3

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5

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12

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9

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54

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27

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25

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1

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1280

    N,N-Diethylnicotinamide

    Others Others
    Nikethamide (N,N-Diethylnicotinamide), one of the respiratory central stimulants, has the potential for respiratory failure research .
    Nikethamide
  • HY-132282

    Bacterial Infection
    Thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent that can be used for respiratory tract infections research .
    Thiamphenicol glycinate hydrochloride
  • HY-P9944

    MEDI 493

    RSV Infection Inflammation/Immunology Cancer
    Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a Kd value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice .
    Palivizumab
  • HY-109004

    BTA-C585

    RSV Infection
    Enzaplatovir (BTA-C585) is an orally bioavailable Inhibitor for respiratory syncytial virus (RSV) infection .
    Enzaplatovir
  • HY-120632

    RSV Infection
    BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 can be used for the research of respiratory tract disease .
    BMS-433771
  • HY-120632A

    RSV Infection
    BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease .
    BMS-433771 dihydrochloride hydrate
  • HY-107355

    Others Inflammation/Immunology
    Letosteine is an orally active, potent and safe expectorant. Letosteine dissolves bronchial mucus and reduces respiratory inflammation symptoms, and restores gas exchanges and natural defense mechanisms in the lung. Letosteine can be used for acute or chronic respiratory diseases (such as bronchopneumopathies) research[1][2][3].
    Letosteine
  • HY-P99209

    MEDI-524

    RSV Infection
    Motavizumab (MEDI-524) is an anti-human RSV (respiratory syncytial virus) monoclonal antibody. Motavizumab can be used in respiratory syncytial virus infection in high-risk infants research .
    Motavizumab
  • HY-W700643

    Drug Metabolite Potassium Channel Autophagy Cancer
    Di-N-desethyl Amiodarone hydrochloride is a metabolite of Amiodarone (HY-14187). Di-N-desethyl Amiodarone hydrochloride is a strong inhibitor of the respiratory chain .
    Di-N-desethyl amiodarone hydrochloride
  • HY-159104

    Cinnamomum Cassia oil

    Fungal Infection
    Cinnamon bark oil, from Cinnamonum zeylanicum Blume is a antifungal agent against fungi causing respiratory tract mycoses .
    Cinnamon bark oil, from Cinnamonum zeylanicum Blume
  • HY-P99756

    MEDI8897

    RSV Infection
    Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC50 values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections .
    Nirsevimab
  • HY-P3870

    Opioid Receptor Neurological Disease
    DALDA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA shows antinociceptive and respiratory effects .
    DALDA
  • HY-P3870A

    Opioid Receptor Neurological Disease
    DALDA acetate is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA acetate shows antinociceptive and respiratory effects .
    DALDA acetate
  • HY-105762A

    Others Cardiovascular Disease
    Etamiphyllin camsylate is a cardiac stimulant with oral activity that increases cardiac output without increasing heart rate. Etamiphyllin camsylate is also a respiratory stimulant used for respiratory failure, as Etamiphyllin camsylate relaxes the smooth muscles of the bronchi and bronchioles, thereby opening up the airways to relieve chronic obstructive pulmonary disease .
    Etamiphyllin camsylate
  • HY-106908

    WAY-PDA 641

    Phosphodiesterase (PDE) Inflammation/Immunology
    WAY-PDA 641 is a potent and preferential PDE-IV inhibitor, with an IC50 of 0.42 μM for canine trachealis PDE-IV. WAY-PDA 641 induces respiratory muscle relaxation and bronchodilation .
    Filaminast
  • HY-A0111

    Ro 15-8074; Deacetoxycefotaxime

    Antibiotic Bacterial Infection
    Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .
    Cefetamet
  • HY-A0111A

    Ro15-8074/001; Deacetoxycefotaxime sodium

    Antibiotic Bacterial Infection
    Cefetamet sodium is a cephalosporin antibiotic. Cefetamet sodium has the potential for the research of both upper and lower community-acquired respiratory tract infections .
    Cefetamet sodium
  • HY-137451A

    (E/Z)-S-600918

    P2X Receptor Inflammation/Immunology
    (E/Z)-Sivopixant ((E/Z)-S-600918) is a potent P2X3 receptor antagonist with an IC50 of 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research .
    (E/Z)-Sivopixant
  • HY-163567

    RSV Infection
    RSV-IN-10 (compound 6a) shows antiviral activity against RSV with the IC50 of 4 μM. RSV-IN-10 can be used for study of respiratory infection .
    RSV-IN-10
  • HY-A0147

    OPC-17116; dl-Grepafloxacin

    Antibiotic Bacterial Infection
    Grepafloxacin (OPC-17116) is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin has high tissue penetration and a promising pharmacodynamic profile .
    Grepafloxacin
  • HY-W702027

    AL842

    Adrenergic Receptor Cardiovascular Disease
    Deterenol hydrochloride (AL842) is a selective beta-agonist. Deterenol hydrochloride causes vasodepressor, anxiety, increasing heart rate, hypotension palpitation and respiratory distress .
    Deterenol hydrochloride
  • HY-108971

    Antibiotic Bacterial Infection
    Demecycline, a tetracycline antibiotic, is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections .
    Demecycline
  • HY-163568

    RSV Infection
    RSV-IN-11 (compound 10b) shows antiviral activity against RSV with the IC50 of 6.32 μM. RSV-IN-10 can be used for study of respiratory infection .
    RSV-IN-11
  • HY-A0147A

    OPC-17116 hydrochloride; dl-Grepafloxacin hydrochloride

    Antibiotic Bacterial Infection
    Grepafloxacin (OPC-17116) hydrochloride is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin hydrochloride has high tissue penetration and a promising pharmacodynamic profile .
    Grepafloxacin hydrochloride
  • HY-15280

    PI3K Inflammation/Immunology
    GSK2292767 is a potent and selective inhibitor of PI3Kδ, with a pIC50 of 10.1. GSK2292767 showing greater than 500-fold selective over the other PI3K isoforms. GSK2292767 can be used for the research of respiratory disease .
    GSK2292767
  • HY-163773

    RSV Infection
    RSV-IN-13 (compound 5c) exhibits antiviral activity against RSV with an EC50 value of 0.78 nM. RSV-IN-13 can be used in the study of respiratory tract infections .
    RSV-IN-13
  • HY-A0161

    Clofedanol; Calmotusin; NSC 113595

    Others Infection
    Chlophedianol (Clofedanol) is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
    Chlophedianol
  • HY-A0111R

    Antibiotic Bacterial Infection
    Cefetamet (Standard) is the analytical standard of Cefetamet. This product is intended for research and analytical applications. Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .
    Cefetamet (Standard)
  • HY-B1717

    Others Inflammation/Immunology
    Oxolamine (SKF-9976) is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine also exhibits anti-inflammatory effect .
    Oxolamine
  • HY-B1717A

    Others Inflammation/Immunology
    Oxolamine (SKF-9976) hydrochloride is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine hydrochloride also exhibits anti-inflammatory effect .
    Oxolamine hydrochloride
  • HY-144058

    JAK Inflammation/Immunology
    JAK-IN-18 is a potent inhibitor of JAK. JAK-IN-18 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases (extracted from patent WO2018204238A1, compound 1) .
    JAK-IN-18
  • HY-144057

    JAK Inflammation/Immunology
    JAK-IN-17 is a potent inhibitor of JAK. JAK-IN-17 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases (extracted from patent WO2021185305A1, compound 9-1) .
    JAK-IN-17
  • HY-156550

    ROCK Inflammation/Immunology
    ROCK-IN-8 (Example 4) is a ROCK inhibitor, with an IC50 value less than 100 nM. ROCK-IN-8 has anti-inflammatory activity. ROCK-IN-8 can be used for research of respiratory and gastro-intestinal diseases .
    ROCK-IN-8
  • HY-B1042

    SKF-9976 citrate; AF-438 citrate

    Others Inflammation/Immunology
    Oxolamine citrate (SKF-9976 citrate) is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine citrate also exhibits anti-inflammatory effect .
    Oxolamine citrate
  • HY-19874

    RSV Infection
    RFI-641 is a selective inhibitor of the respiratory syncytial virus (RSV), with an IC50 of 50 nM. RFI-641 inhibit binding and fusion of enveloped virus via interaction with the viral fusion protein .
    RFI-641
  • HY-150735

    IRAK Inflammation/Immunology
    IRAK4-IN-20 (Compound BAY-1834845) is an orally active IRAK4 inhibitor with an IC50 of 3.55 nM. IRAK4-IN-20 can be used for acute respiratory distress syndrome (ARDS) research .
    IRAK4-IN-20
  • HY-A0161A

    Clofedanol hydrochloride; Calmotusin hydrochloride; NSC 113595 hydrochloride

    Others Infection
    Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
    Chlophedianol hydrochloride
  • HY-N12215

    Others Others
    10-Hydroxyoleuropein (compound 11) is isolated from the rhizome of Cyperus rotundus. 10-Hydroxyoleuropein inhibits the respiratory burst of macrophages (IC50: 693 μM) .
    10-Hydroxyoleuropein
  • HY-N1875

    p-Hydroxybenzyl Et ether

    Others Inflammation/Immunology
    4-(Ethoxymethyl)phenol (p-Hydroxybenzyl Et ether) is a potent antioxidant from Amburana cearensis leaf extract, with in vitro cytogenotoxic properties. Amburana cearensis leaves can be used foe the research of respiratory diseases and inflammations .
    4-(Ethoxymethyl)phenol
  • HY-103250

    Antibiotic Infection
    PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains .
    PF-945863
  • HY-N12305

    RSV Infection
    4,5-O-Dicaffeoyl quinic acid methyl ester (compound 4), a dicaffeoylquinic acid, has potent antiviral activity against respiratory syncytial virus (RSV) with an IC50 of 0.63 μg/mL and a CC50 of 118.68 μg/mL.
    4,5-O-Dicaffeoyl quinic acid methyl ester
  • HY-159688

    Bacterial Infection
    Cefditoren is an orally active antibiotic with broad-spectrum antibacterial activity, capable of inhibiting both Gram-negative and Gram-positive bacteria. It has a MIC50 of 0.25-0.5 mg/L against Streptococcus pneumoniae strains. Cefditoren is effective against respiratory tract infections and skin infections .
    Cefditoren
  • HY-143495

    RSV Influenza Virus Infection
    RSV-IN-3 (Compound 1) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza virus A (IAV). RSV-IN-3 shows anti-RSV activity (EC50 = 32.70 μM) .
    RSV-IN-3
  • HY-143496

    RSV Influenza Virus Infection
    RSV-IN-4 (Compound 2) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza virus A (IAV). RSV-IN-4 shows anti-RSV activity (EC50 = 11.76 μM) .
    RSV-IN-4
  • HY-B0372A
    Bromhexine hydrochloride
    3 Publications Verification

    SARS-CoV Autophagy HIV Metabolic Disease
    Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .
    Bromhexine hydrochloride
  • HY-B1551

    Benzononatine

    Sodium Channel Neurological Disease
    Benzonatate (Benzononatine) is a peripheral oral antitussive that dampens the activity of cough stretch receptors. Benzonatate has sodium channel-blocking properties and local anesthetic effects on the respiratory stretch receptors due to a tetracaine-like metabolite .
    Benzonatate
  • HY-B0455B

    SC47111A (aspartate)

    Bacterial Antibiotic Infection
    Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
    Lomefloxacin (aspartate)
  • HY-19042

    YM 638

    Leukotriene Receptor Inflammation/Immunology
    YM-16638 is an orally active leukotriene (LT) antagonist. YM-16638 can inhibit the production of LTC4, LTD4, and LTE4 in guinea pig trachea, with IC50 values of 0.05 μM, 0.16 μM, and 0.096 μM, respectively. YM-16638 has a dose-dependent inhibitory effect on antigen-induced early and late respiratory responses in allergic sheep .
    YM-16638
  • HY-N2913

    Phosphodiesterase (PDE) Inflammation/Immunology Cancer
    Ayanin is a bioflavonoid isolated from Psychotria serpens. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al .
    Ayanin
  • HY-108402

    Penicillin-binding protein (PBP) Bacterial Antibiotic Infection
    Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
    Cefodizime

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