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human blood

" in MedChemExpress (MCE) Product Catalog:

242

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4

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10

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20

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3

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5

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118870
    γ-Globulins from human blood

    		Endogenous Metabolite Inflammation/Immunology Cancer
    γ-Globulins from human blood are a class of proteins in the blood. γ-Globulin is a protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. γ-Globulins from human blood is used for common variable immunodeficiency
    γ-Globulins from human blood
  • HY-125859A
    Myeloperoxidase, human white blood cells

    MPO

    		 Bacterial Inflammation/Immunology
    Myeloperoxidase, human white blood cells (MPO) is a peroxidase. In Myeloperoxidase, human white blood cells mediate oxidative stress by promoting the production of reactive oxygen species (ROS) and active nitrogen (RNS), regulating the polarization and inflammation-related signaling pathways of microglia and neutrophils. Myeloperoxidase, human white blood cells has antibacterial activity .
    Myeloperoxidase, human white blood cells
  • HY-137892
    GSK620

    		Epigenetic Reader Domain Inflammation/Immunology
    GSK620 is a potent and orally active pan-BD2 inhibitor with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood .
    GSK620
  • HY-153440
    JAK-IN-25

    		JAK Cancer
    JAK-IN-25 (compound 19) is a potent JAK inhibitor with IC50s of 6 nM, 21 nM, 8 nM, 1051 nM for TYK2, JAK1, JAK2, JAK3, respectively. JAK-IN-25 inhibits human whole blood IL-12 (HEB IL-12) with an IC50 of 28 nM. JAK-IN-25 has the potential for cancer research .
    JAK-IN-25
  • HY-16276
    Osilodrostat
    4 Publications Verification

    LCI699

    		 Mineralocorticoid Receptor Cardiovascular Disease Inflammation/Immunology Cancer
    Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS) .
    Osilodrostat
  • HY-E70361
    Whole Leukocyte Esterase, Human

    Unsonicated White blood Cell Esterase, WBC Esterase

    		 Others Others
    Whole Leukocyte Esterase, Human (Unsonicated White Blood Cell Esterase, WBC Esterase) is a biological material or organic compound that can be used in life science research .
    Whole Leukocyte Esterase, Human
  • HY-P5722
    Peptide 5f

    		Bacterial Infection
    Peptide 5f is an antimicrobial peptide derived from wasp venom. Peptide 5f has antimicrobial activity against bacteria and fungi. Peptide 5f has little hemolytic activity on human red blood cells .
    Peptide 5f
  • HY-134375
    cAIMP

    Cyclic Adenosine-Inosine Monophosphate

    		 NF-κB IFNAR Inflammation/Immunology
    cAIMP (Cyclic Adenosine-Inosine Monophosphate) is an effective synthetic cyclic dinucleotide. cAIMP activates IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). cAIMP induces the secretion of IFNs and pro-inflammatory cytokines in vitro in human blood, with an EC50 of 6.4 μmol/L .
    cAIMP
  • HY-W011297
    Methyl arachidonate

    Arachidonic acid methyl ester

    		 Others Metabolic Disease
    Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
    Methyl arachidonate
  • HY-153673
    PROTAC IRAK4 degrader-8

    		IRAK PROTACs Cancer
    PROTAC IRAK4 degrader-8 (Compound 2) is a PROTAC IRAK4 degrader (IC50: 15.5 nM). PROTAC IRAK4 degrader-8 degrades IRAK4 in THP-1 cells (DC50: 1.8 nM)。PROTAC IRAK4 degrader-8 also inhibits L-6 production in human whole blood and LPS-induced human PBMC cells, with IC50s of 246 nM and 2.2 nM respectively .
    PROTAC IRAK4 degrader-8
  • HY-16276A
    Osilodrostat phosphate
    4 Publications Verification

    LCI699 phosphate

    		 Mineralocorticoid Receptor Cardiovascular Disease Cancer
    Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) .
    Osilodrostat phosphate
  • HY-162845
    TLR7/8 agonist 11

    		Toll-like Receptor (TLR) Inflammation/Immunology
    TLR7/8 agonist 11 (compound 30) is a potent agonist of hTLR7 and hTLR8, with EC50s of 31.1 nM and 13.1 nM, respectively. TLR7/8 agonist 11 plays an important role in adaptive and innate immune responses .
    TLR7/8 agonist 11
  • HY-113098
    2-Oxovaleric acid

    		Endogenous Metabolite Metabolic Disease
    2-Oxovaleric acid is a keto acid that is found in human blood.
    2-Oxovaleric acid
  • HY-E70393
    Human Factor VIIa

    		Factor VIIa Others
    Human Factor VIIa is a vitamin K-dependent serine protease that is involved in the blood coagulation process. Human Factor VIIa activates Factor X, which causes the conversion of prothrombin to thrombin and the conversion of fibrinogen to fibrin, leading to the formation of blood clots. Human Factor VIIa exhibits the potential to ameliorate Hemophilia .
    Human Factor VIIa
  • HY-E70393B
    Human Factor Xa

    		Others Others
    Human Factor Xa is a blood coagulation protease. Human Factor Xa is used in research of novel anticoagulant development .
    Human Factor Xa
  • HY-105207
    L 696229

    		HIV Infection
    L 696229 is a specific inhibitor ofhuman immunodeficiency virus type 1 (HIV-1)reverse transcriptase (RT) activity that possesses antiviral activity .
    L 696229
  • HY-E70393C
    Human Factor XIa

    		Others Others
    Human Factor XIa is a blood coagulation protease. Human Factor XIa activates the Factor IX and Factor V, resulting in the generation of thrombin and fibrin .
    Human Factor XIa
  • HY-133608
    4,6-Dichloroguaiacol

    		Others Inflammation/Immunology
    4,6-Dichloroguaiacol induces biochemical and morphological changes in human peripheral blood lymphocytes in vitro .
    4,6-Dichloroguaiacol
  • HY-107037
    Tolmesoxide

    RX71107

    		 Others Cardiovascular Disease
    Tolmesoxide (RX71107) is a peripheral vascular dilator with blood pressure lowering activity. Tolmesoxide has shown direct vasodilation in the human forearm arterial bed and dorsal hand vein. Tolmesoxide can dose-dependently increase blood flow in the forearm and produce dilation during contraction of the dorsal hand veins. Tolmesoxide can be used to study high blood pressure and angina .
    Tolmesoxide
  • HY-165398
    Leucylleucine methyl ester

    		Others Others
    Leucylleucine methyl ester is a lysosomotropic agent that can be used to eliminate gamma delta T cells in human peripheral blood .
    Leucylleucine methyl ester
  • HY-E70389
    Human Kallikrein

    		Others Cardiovascular Disease Inflammation/Immunology
    Human Kallikrein is a serine protease that can be found in plasma and tissue. Human Kallikrein has the potential for the research of blood pressure, complement activation, and mediation and maintenance of inflammatory responses .
    Human Kallikrein
  • HY-13344
    PF-8380
    5 Publications Verification

    		 Phosphodiesterase (PDE) Inflammation/Immunology Cancer
    PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood.
    PF-8380
  • HY-13344A
    PF-8380 hydrochloride
    5 Publications Verification

    		 Phosphodiesterase (PDE) Inflammation/Immunology Cancer
    PF-8380 hydrochloride is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood.
    PF-8380 hydrochloride
  • HY-100244
    NS1652

    		Chloride Channel Neurological Disease
    NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells.
    NS1652
  • HY-139414
    Lysophosphatidylcholines
    1 Publications Verification

    		 Interleukin Related p38 MAPK ERK Apoptosis Inflammation/Immunology
    Lysophosphatidylcholines is an orally active lysolipid and a component of oxidized low density lipoprotein (LDL). Lysophosphatidylcholines induces cell injury, the production of IL-1β and apoptosis. Lysophosphatidylcholines has a proactive effect on sepsis .
    Lysophosphatidylcholines
  • HY-18725
    P2X7-IN-2

    		P2X Receptor Interleukin Related Cardiovascular Disease Inflammation/Immunology
    P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 can be used for the research of autoimmunity, inflammation and cardiovascular disease .
    P2X7-IN-2
  • HY-18725A
    P2X7-IN-2 TFA

    		P2X Receptor Interleukin Related Cardiovascular Disease Inflammation/Immunology
    P2X7-IN-2 TFA (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 TFA inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 TFA can be used for the research of autoimmunity, inflammation and cardiovascular disease .
    P2X7-IN-2 TFA
  • HY-A0168A
    Regadenoson hydrate

    CVT-3146 hydrate

    		 Adenosine Receptor Cardiovascular Disease
    Regadenoson hydrate (NSC 169186) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson hydrate also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
    Regadenoson hydrate
  • HY-A0168
    Regadenoson
    1 Publications Verification

    CVT-3146

    		 Adenosine Receptor Cardiovascular Disease Cancer
    Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
    Regadenoson
  • HY-E70393D
    Human Factor Alpha XIIa

    		Others Others
    Human Factor Alpha XIIa is a blood coagulation protease, which increases the clotting potential. Human Factor Alpha XIIa exhibits a fibrinolysis protein homologous heavy chain, indicating its function in fibrinolysis .
    Human Factor Alpha XIIa
  • HY-115708
    C22 Phytoceramide (t18:0/22:0)

    Cer(t18:0/22:0); Ceramide (t18:0/22:0); C22 Phytosphingosine (t18:0/22:0)

    		 Endogenous Metabolite Metabolic Disease
    C22 Phytoceramide is a sphingolipid that has been found in Moro blood orange (C. sinensis) peels. It has also been found in primary human astrocytes.
    C22 Phytoceramide (t18:0/22:0)
  • HY-P5792
    Atrial natriuretic peptide (3-28) (human)

    ANP (3-28) (human)

    		 Endothelin Receptor Cardiovascular Disease Metabolic Disease
    Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)) is a peptide hormone that is synthesized and secreted by the atrial myocardium. Atrial natriuretic peptide (3-28) (human) is involved in the regulation of blood pressure, fluid balance, and electrolyte homeostasis .
    Atrial natriuretic peptide (3-28) (human)
  • HY-10437A
    Setileuton tosylate

    MK-0633 tosylate

    		 Lipoxygenase Inflammation/Immunology
    Setileuton tosylate is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively .
    Setileuton tosylate
  • HY-107275
    Ebeiedinone

    		Cholinesterase (ChE) Neurological Disease
    Ebeiedinone, a steroidal alkaloid from Fritillaria species, inhibits the bioactivity of human whole blood cholinesterase (ChE) at the concentration of 0.1 mM, with the inhibitory effects of 69.0% .
    Ebeiedinone
  • HY-N11691
    Thapsigargicin

    Thapsigargicine

    		 Others Inflammation/Immunology
    Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets .
    Thapsigargicin
  • HY-E70393H
    Human Factor XIIIa

    		Others Others
    Human Factor XIIIa is a transglutaminase, which catalyzes the cross-linking of proteins and stabilizes the blood clots. Human Factor XIIIa protects the clots from degradation by fibrinolytic enzymes, which is important for maintaining hemostasis and preventing excessive bleeding .
    Human Factor XIIIa
  • HY-151894
    I-BET432

    		Epigenetic Reader Domain Cancer
    I-BET432 is a BET inhibitor. I-BET432 inhibits BRD4 N-terminal bromodomain (BD1) and the C-terminal bromodomain (BD2) with pIC50 values of 7.5 and 7.2, respectively. I-BET432 can be used as an oral candidate quality molecule for the research of multiple oncology and inflammatory diseases .
    I-BET432
  • HY-155357
    Antibacterial agent 160

    		Bacterial Infection
    Antibacterial agent 160 is a potent antibacterial agents. Antibacterial agent 160 can rapidly kill bacterial and inhibits bacterial biofilm formation. Antibacterial agent 160 affects the normal function of DNA and leads cell death .
    Antibacterial agent 160
  • HY-U00170
    Bunaprolast

    U66858

    		 Leukotriene Receptor Prostaglandin Receptor Lipoxygenase Inflammation/Immunology Endocrinology
    Bunaprolast (U66858) is a potent inhibitor of LTB4 production in human whole blood. Bunaprolast (U66858) also exhibits significant inhibition of lipoxygenase and TXB2 release.
    Bunaprolast
  • HY-P2273
    Calcitonin (human)

    		CGRP Receptor Metabolic Disease
    Calcitonin (human) is a hypocalcemic hormone. Calcitonin can lower blood calcium levels and inhibit bone resorption. Calcitonin can be used in hypercalcemia or osteoporosis research .
    Calcitonin (human)
  • HY-162664
    STING antagonist 1

    		STING Inflammation/Immunology
    STING antagonist 1 (Compound 107) is the antagonist for STING with an IC50 of 3.8 nM. STING antagonist 1 exhibits inhibitory efficacy in human whole blood, with IC50 of 31 nM .
    STING antagonist 1
  • HY-10437
    Setileuton

    MK-0633

    		 Lipoxygenase Inflammation/Immunology
    Setileuton (MK-0633) is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively .
    Setileuton
  • HY-107781
    PAT-505

    		Phosphodiesterase (PDE) Inflammation/Immunology
    PAT-505 is a potent, selective, noncompetitive and orally available autotaxin inhibitor, with an IC50 of 2 nM in Hep3B cells, 9.7 nM in human blood and 62 nM in mouse plasma.
    PAT-505
  • HY-162457
    Mn007

    		Others Infection
    Mn007 is a potent inhibitor of bovine pancreatic DNase I, with the IC50 of 45 μM, by forming molecular aggregation. Mn007 shows suppression of S. pyogenes growth in human whole blood .
    Mn007
  • HY-156126
    Lentztrehalose C

    		Others Others
    Lentztrehalose C (compound LTC) is a trehalose analogue with high stability in microbial and mammalian cells. It can be detected in the blood of mice and is ultimately excreted in feces and urine. It can induce autophagy in human cancer cells.
    Lentztrehalose C
  • HY-A0168R
    Regadenoson (Standard)

    		Adenosine Receptor Cardiovascular Disease
    Regadenoson (Standard) is the analytical standard of Regadenoson. This product is intended for research and analytical applications. Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
    Regadenoson (Standard)
  • HY-W050031
    (S)-3-Hydroxybutanoic acid
    2 Publications Verification

    (S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid

    		 Endogenous Metabolite Others
    (S)-3-Hydroxybutanoic acid is a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. In humans, 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.
    (S)-3-Hydroxybutanoic acid
  • HY-120606
    A-78773

    		Lipoxygenase Inflammation/Immunology
    A-78773 is a 5-lipoxygenase inhibitor. A-78773 can inhibit the formation of LTB4 in human whole blood and human neutrophils, with IC50 values of 85 nM and 20 nM, respectively. A-78773 can be used in the study of inflammation-related diseases .
    A-78773
  • HY-14744B
    Levamlodipine hydrochloride

    (S)-Amlodipine hydrochloride; Levoamlodipine hydrochloride

    		 Calcium Channel Cardiovascular Disease
    Levamlodipine hydrochloride (Levoamlodipine hydrochloride) is a dihydropyridine calcium channel blocker. Levamlodipine hydrochloride reduces the inflow of calcium ions by blocking L-type calcium channels on vascular smooth muscle cells, thereby leading to vasodilation, lower blood pressure and lighten the burden on the heart. Levamlodipine hydrochloride has activity to lower blood pressure and relieve angina. The binding properties of Levamlodipine hydrochloride to human serum albumin (HSA) contribute to the study of drug transport and release mechanisms in the body .
    Levamlodipine hydrochloride
  • HY-106093
    Eltenac

    		COX Inflammation/Immunology
    Eltenac, a non-steroidal anti-inflammatory drug (NSAID), is a COX inhibitor. Eltenac shows IC50 of 0.03 μM for both COX-1 and COX-2 in isolated human whole blood .
    Eltenac

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