Search Result
Results for "
Insecticidal
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
46
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-162497
-
|
nAChR
|
Others
|
Insecticidal agent 12 (Compound F45) has insecticidal activity (LC50: 2.94 μg/mL). Insecticidal agent 12 is an nAChR inhibitor .
|
-
-
- HY-157162
-
|
Cholinesterase (ChE)
|
Others
|
Insecticidal agent 5 (compound 8) is an AChE-targeting insecticide with an LD50 of 27.65 ppm against the cotton leafworm Spodoptera littoralis .
|
-
-
- HY-158327
-
|
Parasite
|
Others
|
Insecticidal agent 9 (Compound I-17) is an insecticide with good insecticidal activity. Insecticidal agent 9 has LC50 values of 93.32 mg/L and 114.79 mg/L against Plutella xylostella and Ostrinia furnacalis respectively, and exhibits a mortality rate of up to 86.1% against Spodoptera frugiperda at a concentration of 500 mg/L. Insecticidal agent 9 can act simultaneously on the ecdysone receptor (EcR) and three chitinases (OfChtI, OfChtII, and OfChi-h), demonstrating good binding activity (to EcR) and inhibitory rates (to the three chitinases). Insecticidal agent 9 can be used in research for pest management .
|
-
-
- HY-P10390
-
|
Parasite
|
Infection
|
Insecticidal agent 11 (compound Q6) is a potent insect growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .
|
-
-
- HY-168570
-
|
Parasite
|
Infection
|
Insecticidal agent 16 (compound A21) is a potent insecticidal agent. Insecticidal agent 16 shows insecticidal activities against Plutella xylostella and Spodoptera frugiperda with LC50 values of 1.2 and 13.2 µg/mL, respectively .
|
-
-
- HY-156256
-
|
Bacterial
|
Infection
|
Insecticidal agent 4 (compound IA-8) is an aryl isoxazoline derivative with insecticidal activity against M. separate .
|
-
-
- HY-163776
-
|
Others
|
Others
|
Insecticidal agent 13 (compound A15) is a phenylpyrazole derivative with insecticidal and acaricidal activities, which can be used in the research of agricultural pest control .
|
-
-
- HY-149864
-
|
Others
|
Others
|
Insecticidal agent 3 is a multichitinase inhibitors, belongs to insect growth regulators (IGRs),with Kis of 0.8μM, 11.9 μM, and 2.3 μM for Of ChtI, Of ChtII, and Of Chi-h, respectively. Insecticidal agent 3 exhibits insecticidal activity against two lepidopteran pests by interfering with normal insect growth and molting .
|
-
-
- HY-142916
-
|
Others
|
Others
|
Insecticidal agent 1 displays more potent insecticidal activity than obacunone and toosendanin.
|
-
-
- HY-149697
-
|
Parasite
|
Others
|
Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC50 value of 0.6308 µM against S. frugiperda RyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases .
|
-
-
- HY-163157
-
|
Parasite
|
Others
|
Insecticidal agent 7 (Compound 21m) is an insecticide that targets the insect ryanodine receptors (RyRs) with a LC50 of 0.0937 mg/L for the Plutella xylostella. Insecticidal agent 7 (Compound 21m) exhibits good selectivity and low toxicity towards non-target organisms .
|
-
-
- HY-W131444
-
|
Others
|
Others
|
Insecticidal agent 15 (compound 8f) is a potent insecticidal agent that shows LD50 of 4.27 nmol/mg for adult female Ae. Aegypti .
|
-
-
- HY-162279
-
|
Others
|
Infection
|
Insecticidal agent 8 ((S)-4a-14) is an insecticidal agent that has significant selective biological against Aphis craccivora Koch and Plutella xylostella .
|
-
-
- HY-163560
-
|
Parasite
|
Others
|
Insecticidal agent 10 (Compound 8c) is an inhibitor for chitinase, which inhibits OfChi-h and OfChtI with IC50 of 1.51 and 9.21 nM, respectively. Insecticidal agent 10 inhibits growth of Ostrinia furnacalis with LC50 of 22.14 mg/L .
|
-
-
- HY-169169
-
|
Parasite
|
Infection
|
Insecticidal agent 14 (compound 8a) shows potent insecticidal activity against Plutella xylostella and Mythimna separata, with LC50 values of 0.79 and 9.17 mg/L against P. xylostella, respectively, and 3.58 and 83.09 mg/L against M. separata, respectively .
|
-
-
- HY-153732
-
|
Parasite
|
Infection
|
Insecticidal agent 2 (example 2) is a pesticide that exhibits potent growth-retarding activity against pests .
|
-
-
- HY-122233
-
-
-
- HY-B2142
-
Alodan
|
Others
|
Others
|
Chlorbicyclen (Alodan) is organic chloride insecticide .
|
-
-
- HY-132457S
-
-
-
- HY-N3156
-
Dehydroodoratol
|
Others
|
Others
|
Odoratone (Dehydroodoratol) has insecticidal activity (LC50: 154 ppm) .
|
-
-
- HY-122062
-
|
Others
|
Others
|
Fenoxycarb, a juvenile hormone, is an insecticide and can be used for agricultural pest control .
|
-
-
- HY-122401
-
|
Others
|
Infection
|
Daigremontianin is an insecticidal bufadienolide that can be isolated from K. daigremontiana x tubiflora. Daigremontianin shows insecticidal activity for silkworm .
|
-
-
- HY-B0833
-
|
Others
|
Others
|
Thiamethoxam is a broad spectrum neonicotinoid insecticide .
|
-
-
- HY-167826
-
|
Others
|
Others
|
Spiropidion is a novel tetrameric acid pesticide with highly effective insecticidal and acaricidal activity .
|
-
-
- HY-118659
-
3-Benzylidenephthalide
|
Others
|
Infection
|
Benzalphthalide (3-Benzylidenephthalide), a phthalate compound, is an insecticide .
|
-
-
- HY-N12130
-
|
Others
|
Others
|
Celangulatin D (Compound 2) is an insecticidal sesquiterpene polyol ester isolated from the root bark of the natural Celastrus angulatus. Celangulatin D has insecticidal activity against armyworms. Celangulatin D can be used for insecticidal and anti-tumor research .
|
-
-
- HY-B1973
-
|
Others
|
Others
|
Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities .
|
-
-
- HY-B0830
-
-
-
- HY-W338247
-
|
Others
|
Others
|
Imidaclothiz is a kind of neonicotinoid insecticides. Imidaclothiz has excellent insecticidal effect. Imidaclothiz can be used for the research of sucking and biting insects .
|
-
-
- HY-N3068
-
Nigakilactone I; Simalikalactone B
|
Others
|
Others
|
Picrasin B (Nigakilactone I) can be isolated from the bark of Picrasma quassioides. Picrasin B shows antifeedant and insecticidal activity against Diamondback Moth .
|
-
-
- HY-B1973R
-
|
Others
|
Others
|
Diflubenzuron (Standard) is the analytical standard of Diflubenzuron. This product is intended for research and analytical applications. Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities .
|
-
-
- HY-145299
-
|
nAChR
|
Infection
|
nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator .
|
-
-
- HY-145300
-
|
nAChR
|
Infection
|
nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator .
|
-
-
- HY-119509
-
-
-
- HY-B0830S
-
-
-
- HY-B0830R
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Isoprocarb (Standard) is the analytical standard of Isoprocarb. This product is intended for research and analytical applications. Isoprocarb is carbamate insecticide that widely used to control rice paddy lice and leafhopper. Isoprocarb is also an AChE inhibitor .
|
-
-
- HY-108970
-
|
Proton Pump
Bacterial
Fungal
|
Infection
|
Bafilomycin D is a specific inhibitor of vacuolar-type ATPase (V-ATPase). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity .
|
-
-
- HY-119863
-
|
Others
|
Others
|
Barthrin is a pyrethroid insecticide. The toxicity of Barthrin to housefly (Musca domestica L.) at the 50% mortality level is 14 % of that of Barthrin (HY-B1559) .
|
-
-
- HY-136330
-
|
Bacterial
|
Infection
|
Oxazosulfyl is a potent agricultural fungicide. Oxazosulfyl can be used as an insecticide against major rice pests .
|
-
-
- HY-B2063
-
|
Others
|
Infection
|
Chlorobenzuron is a chitin synthetase inhibitor, acts as an insecticide. Chlorobenzuron can inhibit larvae development and pupate .
|
-
-
- HY-120479
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Cythioate is an organophosphorous insecticide and anthelmintic. Cythioate is an acetylcholinesterase inhibitor which interferes with neuromuscular transmission in ectoparastites .
|
-
-
- HY-162935
-
|
Proton Pump
|
Others
|
V-ATPase-IN-1 (Compound 3b-03) is a Vacuolar-type H +-ATPases (V-ATPase) inhibitor (IC50 = 194.80 μM) that can effectively target the V-ATPase subunit A (Kd = 0.803 μM). V-ATPase-IN-1 exhibits insecticidal activity against M. separata (LC50 = 2.64 mM) and contributes to research in the development of chemical insecticides .
|
-
-
- HY-B0834
-
(RS)-Indoxacarb; DPX-JW062
|
Sodium Channel
|
Neurological Disease
|
Indoxacarb ((±)-Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect sodium channels (Sodium Channel) in nerve preparations and isolated neurons .
|
-
-
- HY-157192
-
|
Others
|
Infection
|
Clothianidin-2-S-propanoic acid is a clothianidin hapten. Clothianidin-2-S-propanoic can be used for the research of insecticide .
|
-
-
- HY-W338247R
-
|
Others
|
Others
|
Imidaclothiz (Standard) is the analytical standard of Imidaclothiz. This product is intended for research and analytical applications. Imidaclothiz is a kind of neonicotinoid insecticides. Imidaclothiz has excellent insecticidal effect. Imidaclothiz can be used for the research of sucking and biting insects .
|
-
-
- HY-W059342
-
YI-5301
|
Biochemical Assay Reagents
|
Infection
|
Etoxazole (YI-5301) is an organofluorine insecticide widely used in agriculture. Etoxazole affects the nymphs, eggs, and larvae of spider mites by inhibiting chitin biosynthesis .
|
-
-
- HY-155388
-
|
Others
|
Others
|
ZK-PI-9 inhibits trehalase. ZK-PI-9 inhibits chitinase activity in female pupae. ZK-PI-9 is an insecticide .
|
-
-
- HY-145298
-
|
nAChR
|
Infection
|
Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs). Dicloromezotiaz can be used to control a broad range of lepidoptera .
|
-
-
- HY-119725
-
|
Parasite
|
Infection
|
Tetradifon is a broad spectrum organochlorine insecticide that can be used to control a wide range of mites .
|
-
-
- HY-124232
-
-
- HY-W775317
-
NNI-1501
|
Others
|
Infection
|
Benzpyrimoxan (NNI-1501) is an insecticide that shows remarkable activity against nymphs of rice planthoppers .
|
-
- HY-B1885
-
|
Parasite
Cholinesterase (ChE)
|
Infection
|
Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols .
|
-
- HY-N7939
-
|
Others
|
Others
|
Celangulin XIX is a insecticidal that can be isolated from Celastrus angulatu. Celangulin XIX has strong insecticidal activity against Mythimna separate with an ED50 of 73.3 μg/g .
|
-
- HY-133167
-
|
Others
|
Others
|
Clothianidin is a neonicotinoid insecticide. Clothianidin shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin has various application methods and high safety for crops .
|
-
- HY-N4250
-
|
Others
|
Infection
|
Periplocoside N, a pregnane glycoside isolated from root powder of Periploca sepium, possesses insecticidal activities against the red imported fire ant .
|
-
- HY-136608
-
|
nAChR
|
Neurological Disease
|
5-AAM-2-CP is a major metabolite of Acetamiprid. Acetamiprid is a neonicotinoid insecticide used worldwide and is a nAChR agonist .
|
-
- HY-136609
-
|
nAChR
|
Neurological Disease
|
5-AMAM-2-CP is a major metabolite of Acetamiprid. Acetamiprid is a neonicotinoid insecticide used worldwide and is a nAChR agonist .
|
-
- HY-B0834R
-
|
Sodium Channel
|
Neurological Disease
|
Indoxacarb (Standard) is the analytical standard of Indoxacarb. This product is intended for research and analytical applications. Indoxacarb ((±)-Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect sodium channels (Sodium Channel) in nerve preparations and isolated neurons .
|
-
- HY-B1093
-
|
Parasite
Cholinesterase (ChE)
|
Infection
|
Fenchlorphos, an organophosphate, is an insecticide. Fenchlorphos is an inhibitor of the enzyme acetylcholinesterase (AChE). Fenchlorphos is able to cause mitochondrial dysfunction .
|
-
- HY-123135
-
|
Others
|
Infection
Cancer
|
Scirpusin B (compound 5) is a dimeric antioxidant isolated from Scirpus maritimus L.. Scirpusin B exhibits antitumor, antifungal, insecticidal, and plant growth inhibitory activities.
|
-
- HY-N7875
-
|
Others
|
Others
|
Celangulin is an insecticidal component isolated from Celastrus angulatus. Celangulin activates the calcium channel on the plasma membrane with increasing the intracellular Ca 2+ after influx from the external. Celangulin activates the calcium channel in the ER .
|
-
- HY-B0823S
-
|
nAChR
|
Neurological Disease
|
Acetamiprid-d3 is the deuterium labeled Acetamiprid. Acetamiprid is a neonicotinoid insecticide. Acetamiprid is a nAChR agonist[1].
|
-
- HY-149399
-
|
Others
GABA Receptor
|
Infection
|
GABA-IN-1 (Compound 6) is a GABA inhibitor. GABA-IN-1 has larvicidal activity and insecticidal effect, with mortality rates of 93% at 50 mg/L .
|
-
- HY-149400
-
|
Others
GABA Receptor
|
Infection
|
GABA-IN-2 (Compound 5) is a GABA inhibitor. GABA-IN-2 has larvicidal activity and insecticidal effect, with mortality rates of 87% at 50 mg/L .
|
-
- HY-133204
-
IKI-7899
|
Others
|
Others
|
Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests .
|
-
- HY-114899
-
-
- HY-B0841
-
-
- HY-B2063R
-
|
Others
|
Infection
|
Chlorobenzuron (Standard) is the analytical standard of Chlorobenzuron. This product is intended for research and analytical applications. Chlorobenzuron is a chitin synthetase inhibitor, acts as an insecticide. Chlorobenzuron can inhibit larvae development and pupate .
|
-
- HY-W059342R
-
|
Biochemical Assay Reagents
|
Infection
|
Etoxazole (Standard) is the analytical standard of Etoxazole. This product is intended for research and analytical applications. Etoxazole (YI-5301) is an organofluorine insecticide widely used in agriculture. Etoxazole affects the nymphs, eggs, and larvae of spider mites by inhibiting chitin biosynthesis .
|
-
- HY-N1520
-
|
Others
|
Infection
|
Rediocide A is a highly modified daphnane with potent insecticidal activity. Rediocide A can be isolated from Trigonostemon reidioides .
|
-
- HY-B0823
-
|
nAChR
|
Neurological Disease
|
Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders .
|
-
- HY-Y0055
-
-
- HY-B1885R
-
|
Parasite
Cholinesterase (ChE)
|
Infection
|
Fenitrothion (Standard) is the analytical standard of Fenitrothion. This product is intended for research and analytical applications. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols .
|
-
- HY-12779
-
HGW-86
|
Parasite
|
Others
|
Cyantraniliprole (HGW-86) is a potent and selective aniline receptor activator with oral activity. Cyantraniliprole has insecticidal and antioxidant activity .
|
-
- HY-W587768
-
S-21074
|
Others
|
Others
|
Metoxadiazone is a type of insecticide that effectively controls a wide range of insects, including cockroaches and ants. Metoxadiazone exerts its insecticidal effect by impacting the nervous system of insects. Metoxadiazone can be used for research into its potential toxicity to humans and other non-target organisms .
|
-
- HY-126780
-
|
Antibiotic
Fungal
|
Infection
|
Nikkomycin N is a nucleoside antibiotic, which is initially produced by Streptomyces tendae. Nikkomycin N exhibits fungicidal and insecticidal properties through inhibition of chitin synthesis .
|
-
- HY-W011035
-
|
Parasite
|
Infection
|
Dodecamethylpentasiloxane is a component of siloxanes and can be used as silicone oil. Dodecamethylpentasiloxane exhibits insecticidal activity against bed bug .
|
-
- HY-133167R
-
|
Others
|
Others
|
Clothianidin (Standard) is the analytical standard of Clothianidin. This product is intended for research and analytical applications. Clothianidin is a neonicotinoid insecticide. Clothianidin shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin has various application methods and high safety for crops .
|
-
- HY-N0073A
-
|
Others
|
Others
|
Spirostan-3-ol is a useful tool to keep bees away from areas recently treated with toxic insecticides .
|
-
- HY-119725R
-
|
Parasite
|
Infection
|
Tetradifon (Standard) is the analytical standard of Tetradifon. This product is intended for research and analytical applications. Tetradifon is a broad spectrum organochlorine insecticide that can be used to control a wide range of mites .
|
-
- HY-N0238
-
Atractydin
|
Others
|
Infection
Inflammation/Immunology
|
Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity .
|
-
- HY-157037
-
|
Parasite
|
Others
|
OfChi-h-IN-2 (compound TQ19) is a potent OfChi-h inhibitor with a Ki value of 0.33 μM. OfChi-h-IN-2 can significantly inhibit the growth and development of Ostrinia nubilalis larvae. OfChi-h-IN-2 can be used in agricultural insecticide research .
|
-
- HY-W010056
-
|
Others
|
Inflammation/Immunology
|
Diethyl fumarate is a decomposition product of Malathion (an insecticide). Diethyl fumarate is a reputed skin irritant. Diethyl fumarate can causes non-immunologic contact urticaria on skin .
|
-
- HY-115584
-
|
Parasite
|
Infection
|
Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods .
|
-
- HY-133167S
-
|
Isotope-Labeled Compounds
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Others
|
Clothianidin-d3 is the deuterium labeled Clothianidin.Clothianidin-d3 is a neonicotinoid insecticide. Clothianidin-d3 shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin-d3 has various application methods and high safety for crops .
|
-
- HY-133204R
-
|
Others
|
Others
|
Chlorfluazuron (Standard) is the analytical standard of Chlorfluazuron. This product is intended for research and analytical applications. Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests .
|
-
- HY-N10743
-
|
Parasite
|
Infection
|
Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide .
|
-
- HY-B1093R
-
|
Parasite
Cholinesterase (ChE)
|
Infection
|
Fenchlorphos (Standard) is the analytical standard of Fenchlorphos. This product is intended for research and analytical applications. Fenchlorphos, an organophosphate, is an insecticide. Fenchlorphos is an inhibitor of the enzyme acetylcholinesterase (AChE). Fenchlorphos is able to cause mitochondrial dysfunction .
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-
- HY-114899S
-
-
- HY-N12548
-
|
Others
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Others
|
Thamnosmonin is a coumarin that can be isolated from Sida acuta and Sida rhombifolia. Thamnosmonin has insecticidal activity .
|
-
- HY-119419
-
|
Cholinesterase (ChE)
Parasite
|
Neurological Disease
|
Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide .
|
-
- HY-119360
-
|
Others
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Others
|
Lilly 18947 (free base) is a selective drug-potentiating agent that synergizes carbamate insecticides. Lilly 18947 (free base) inhibits a variety of detoxication mechanisms in mammals .
|
-
- HY-W587768R
-
|
Others
|
Others
|
Metoxadiazone (Standard) is the analytical standard of Metoxadiazone. This product is intended for research and analytical applications. Metoxadiazone is a type of insecticide that effectively controls a wide range of insects, including cockroaches and ants. Metoxadiazone exerts its insecticidal effect by impacting the nervous system of insects. Metoxadiazone can be used for research into its potential toxicity to humans and other non-target organisms .
|
-
- HY-B0841R
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Acephate (Standard) is the analytical standard of Acephate. This product is intended for research and analytical applications. Acephate is a broad-spectrum anticholinesterase insecticide. Acephate acts via inhibiting AChE (Cholinesterase (ChE)) activity of insects. Acephate is used for control of several species of insects in agriculture and in horticulture .
|
-
- HY-136394
-
-
- HY-132409S
-
-
- HY-Y0055R
-
|
Antibiotic
Fungal
Bacterial
Parasite
|
Infection
Neurological Disease
|
Phenothiazine (Standard) is the analytical standard of Phenothiazine. This product is intended for research and analytical applications. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases .
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-
- HY-B0823R
-
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nAChR
|
Neurological Disease
|
Acetamiprid (Standard) is the analytical standard of Acetamiprid. This product is intended for research and analytical applications. Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders .
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-
- HY-N3990
-
(-)-Hardwikiic acid
|
Sodium Channel
|
Infection
Neurological Disease
|
Hardwickiic acid ((-)-Hardwikiic acid) is an antinociceptive compound that blocks Tetrodotoxin-sensitive voltage-dependent sodium channels. Hardwickiic acid shows insecticidal activity .
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- HY-12779R
-
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Parasite
|
Others
|
Cyantraniliprole (Standard) is the analytical standard of Cyantraniliprole. This product is intended for research and analytical applications. Cyantraniliprole (HGW-86) is a potent and selective aniline receptor activator with oral activity. Cyantraniliprole has insecticidal and antioxidant activity .
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-
- HY-114899R
-
|
Cholinesterase (ChE)
Parasite
|
Neurological Disease
|
Azamethiphos (Standard) is the analytical standard of Azamethiphos. This product is intended for research and analytical applications. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .
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-
- HY-119604
-
|
Antibiotic
Bacterial
|
Infection
|
Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin .
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- HY-W087962
-
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Parasite
|
Others
|
Phenylphosphonic acid (Compound 1) is a synthetic pyrethroid insecticide that can effectively control some underground pests. Phenylphosphonic acid also can be a ligand in some metal-catalyzed reactions, which is promising for research of metal phosphonates comprising layered structures and pesticides .
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- HY-B0835
-
|
Apoptosis
|
Cardiovascular Disease
Neurological Disease
|
Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals .
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-
- HY-W011035R
-
|
Parasite
|
Infection
|
Dodecamethylpentasiloxane (Standard) is the analytical standard of Dodecamethylpentasiloxane. This product is intended for research and analytical applications. Dodecamethylpentasiloxane is a component of siloxanes and can be used as silicone oil. Dodecamethylpentasiloxane exhibits insecticidal activity against bed bug .
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- HY-B1953
-
|
Parasite
DNA Stain
|
Infection
|
Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables . Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions .
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-
- HY-118504
-
|
nAChR
|
Neurological Disease
|
Sulfoxaflor is a sulfoximine insecticide and is an agonist of nAChR1 and nAChR2 subtypes. Sulfoxaflor is used for the control of sap-feeding insects such as Myzus persicae, Aphis gossypii, Bemissia tabaci and Nilaparvata lugens .
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-
- HY-W089538
-
|
Bacterial
|
Infection
|
2-Ethyl-6-methylphenol, an alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol exhibits insecticidal and bactericidal activities .
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-
- HY-115584R
-
|
Parasite
|
Infection
|
Lufenuron (Standard) is the analytical standard of Lufenuron. This product is intended for research and analytical applications. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods .
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-
- HY-126741
-
|
Apoptosis
Parasite
NF-κB
Bcl-2 Family
Caspase
|
Infection
Inflammation/Immunology
Cancer
|
Azadirachtin is an oral active triterpenoid compound with anticancer, antimalarial, anti-inflammatory, and insecticidal activities. Azadirachtin induces cell apoptosis through the mitochondrial pathway (by inhibiting Bcl-2/Bax ratio or activating Apaf-1 and caspase-3) or through death receptors (by inhibiting TNFR activation). Additionally, Azadirachtin exerts its anti-inflammatory effects by inhibiting NF-кB signaling pathway activation, and it exhibits insecticidal activity by inducing apoptosis in insect cells .
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-
- HY-B1881
-
|
Parasite
Cholinesterase (ChE)
|
Infection
|
Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains .
|
-
- HY-119419R
-
|
Cholinesterase (ChE)
Parasite
|
Neurological Disease
|
Pirimicarb (Standard) is the analytical standard of Pirimicarb. This product is intended for research and analytical applications. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide .
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-
- HY-138800
-
|
nAChR
|
Neurological Disease
|
Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity .
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-
- HY-121366
-
RU-15525
|
Calcium Channel
|
Others
|
Kadethrin is a synthetic pyrethroid that acts as an insecticide. Kadethrin can affect the binding of [3H] full-histamine toxin ([3H]H12-HTX) to the nicotinic acetylcholine (Ach) receptor/channel binding sites, and it inhibits the Ca 2+ flux through the receptor ion channels .
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-
- HY-N10013
-
|
Others
|
Others
|
β-Damascone is an aroma active rice volatile and is widely used in perfume compositions. β-Damascone has also received certain attention as a potential cancer chemopreventive and a mosquito and muscoid insecticide .
|
-
- HY-N1621
-
|
Fungal
Parasite
|
Infection
|
1-Deacetylnimbolinin B is a nimbolinin-type limonoid isolated from the fruits of Melia toosendan. Limonoids are a class of highly oxygenated nortriterpenoids that exhibit insecticidal, antifungal, nematicidal and cytotoxic properties .
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-
- HY-163352
-
|
Others
|
Infection
|
Chitinase-IN-6 (Compound 4h) is a potent dual-Chitinase inhibitor, with Ki values of 1.82 and 2.00 μM against OfChtI and OfChi-h, respectively. Chitinase-IN-6 exhibits certain growth inhibition effects against Ostrinia furnacalis. Chitinase-IN-6 is a potential novel insecticide candidate friendly to nontarget organisms .
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-
- HY-N8355
-
|
Endogenous Metabolite
|
Infection
|
Beauveriolide I is the metabolite of Entomopathogenic Fungi Beauveria sp.. Beauveriolide I (1) exhibits moderate insecticidal activities against Spodoptera litura and Callosobruchus chinensis .
|
-
- HY-N3230
-
Murraxocin
|
TRP Channel
|
Inflammation/Immunology
|
Murpanicin (murraxocin) is a coumarin that is a thermosensitive transient receptor potential vanilloid 2 (TRPV2) channel inhibitor. Murpanicin has significant anti-inflammatory and insecticidal effects.
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-
- HY-B0835R
-
|
Apoptosis
|
Cardiovascular Disease
Neurological Disease
|
Fenobucarb (Standard) is the analytical standard of Fenobucarb. This product is intended for research and analytical applications. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals .
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-
- HY-W009811
-
|
Others
|
Others
|
2-Tridecanone, a nonalkaloid insecticide, is isolated from the wild tomato Lycopersicon hirsutum f. glabratum. 2-Tridecanone is a volatile organic compound .
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-
- HY-145296
-
|
nAChR
|
Infection
|
Triflumezopyrim, a mesoionic insecticide, has high efficiency at a low dosage, and is mainly used to control hopper species. Triflumezopyrim mainly acts on the nicotinic acetylcholine receptor (nAChR) inhibition, which is very highly efficient, rapidly effective, and nearly nontoxic to nontarget arthropods .
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-
- HY-156339
-
|
GABA Receptor
|
Others
|
GABA receptor Antagonist 1 (compound 7w) inhibits Px RDL1 GABAR with an IC50 value of 7.08 nmol/L. GABA receptor Antagonist 1 shows insecticide activity against P. xylostella, S. frugiperda, S. exigua, and S. litura, with LC50 of 0.09, 0.84, 0.87, and 0.68 mg/L respectively. GABA receptor Antagonist 1 shows a medium toxicity to honeybee (48 h, ID50 = 2.22 μg/adult), and low toxicity to zebrafish (LC50: 42.4 mg/L) .
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-
- HY-B1953R
-
|
Parasite
DNA Stain
|
Infection
|
Thiacloprid (Standard) is the analytical standard of Thiacloprid. This product is intended for research and analytical applications. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables . Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions .
|
-
- HY-N10695
-
|
Parasite
|
Infection
|
Celangulatin C is an insecticidal sesquiterpene polyol ester, that can be isolated from the root bark of Pseudolarix kaempferi. Celangulatin C shows LD50 against Mythimna separata of 280.4 μg/mL .
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-
- HY-145295
-
|
nAChR
|
Infection
|
Flupyradifurone is a systemic nAChR agonist that interferes with signal transduction in the central nervous system of sucking pests. Flupyradifurone can be used as a butenolide insecticide .
|
-
- HY-N8668
-
|
Others
|
Others
|
Eudesmane K exhibits insecticidal activity against main pests to crops Lipaphis erysimi, Sitobion avenae, Rhopalosiphum padi, and Aphis craccivora .
|
-
- HY-118504R
-
|
nAChR
|
Neurological Disease
|
Sulfoxaflor (Standard) is the analytical standard of Sulfoxaflor. This product is intended for research and analytical applications. Sulfoxaflor is a sulfoximine insecticide and is an agonist of nAChR1 and nAChR2 subtypes. Sulfoxaflor is used for the control of sap-feeding insects such as Myzus persicae, Aphis gossypii, Bemissia tabaci and Nilaparvata lugens .
|
-
- HY-B0831
-
|
Oxidative Phosphorylation
Reactive Oxygen Species
|
Others
|
Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .
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-
- HY-B1946
-
|
Others
|
Others
|
Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects .
|
-
- HY-138800R
-
|
nAChR
|
Neurological Disease
|
Spinosad (Standard) is the analytical standard of Spinosad. This product is intended for research and analytical applications. Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity .
|
-
- HY-N9496
-
|
Others
|
Infection
|
Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity .
|
-
- HY-133721
-
|
HBV
|
Infection
Inflammation/Immunology
|
Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities .
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-
- HY-B1881R
-
|
Parasite
Cholinesterase (ChE)
|
Infection
|
Pirimiphos-methyl (Standard) is the analytical standard of Pirimiphos-methyl. This product is intended for research and analytical applications. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains .
|
-
- HY-B1837
-
|
Sodium Channel
|
Infection
|
Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture,veterinary, insecticide,pyrethroid and stored product .
|
-
- HY-N10697
-
Celangulatin E
|
Parasite
|
Infection
|
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD50 against Mythimna separata of 1656.4 μg/mL .
|
-
- HY-B0835S
-
|
Apoptosis
|
Neurological Disease
|
Fenobucarb-d3 is the deuterium labeled Fenobucarb. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis[1].
|
-
- HY-16974
-
|
GABA Receptor
Chloride Channel
Parasite
|
Infection
|
Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod .
|
-
- HY-121328
-
S-2852F
|
Parasite
|
Infection
Neurological Disease
|
Empenthrin (S-2852F) is a synthetic pyrethroid. Empenthrin can be used in insecticides. Empenthrin shows a clear species-specificity in the inhibitory effect on the Pentobarbital (PTB)-metabolizing enzyme(s). Empenthrin prolongs PTB induced-sleeping time in mice through an inhibition of the PTB-metabolizing enzyme(s) in the liver, an effect that does not occur in rats. Empenthrin shows a clear species-specificity in the inhibitory effect on the PTB-metabolizing enzyme(s) .
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-
- HY-N10013R
-
|
Others
|
Others
|
β-Damascone (Standard) is the analytical standard of β-Damascone. This product is intended for research and analytical applications. β-Damascone is an aroma active rice volatile and is widely used in perfume compositions. β-Damascone has also received certain attention as a potential cancer chemopreventive and a mosquito and muscoid insecticide .
|
-
- HY-126741R
-
|
Apoptosis
Parasite
NF-κB
Bcl-2 Family
Caspase
|
Infection
Inflammation/Immunology
Cancer
|
Azadirachtin (Standard) is the analytical standard of Azadirachtin. This product is intended for research and analytical applications. Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4 .
|
-
- HY-B0831R
-
|
Oxidative Phosphorylation
Reactive Oxygen Species
|
Others
|
Buprofezin (Standard) is the analytical standard of Buprofezin. This product is intended for research and analytical applications. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .
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-
- HY-B1946R
-
|
Others
|
Others
|
Dimethoate (Standard) is the analytical standard of Dimethoate. This product is intended for research and analytical applications. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects .
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-
- HY-151470
-
|
Parasite
|
Others
|
Chitinase-IN-5 (8i) is a potent chitinase OfChi-h inhibitor with an IC50 value of 0.051 μM. Chitinase-IN-5 shows good insecticidal activity, it can be used for the research of green pest control and management .
|
-
- HY-N8472
-
|
GABA Receptor
|
Infection
|
Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC50?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity .
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-
- HY-145295R
-
|
nAChR
|
Infection
|
Flupyradifurone (Standard) is the analytical standard of Flupyradifurone. This product is intended for research and analytical applications. Flupyradifurone is a systemic nAChR agonist that interferes with signal transduction in the central nervous system of sucking pests. Flupyradifurone can be used as a butenolide insecticide .
|
-
- HY-N9496R
-
|
Others
|
Infection
|
Piperitone (Standard) is the analytical standard of Piperitone. This product is intended for research and analytical applications. Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity .
|
-
- HY-B0836
-
|
Parasite
Sodium Channel
|
Infection
Neurological Disease
Endocrinology
|
λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system .
|
-
- HY-156082
-
|
Parasite
Calcium Channel
|
Others
|
RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity .
|
-
- HY-16974R
-
|
GABA Receptor
Chloride Channel
Parasite
|
Infection
|
Afoxolaner (Standard) is the analytical standard of Afoxolaner. This product is intended for research and analytical applications. Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod .
|
-
- HY-B1971
-
-
- HY-B0840
-
|
Parasite
Oxidative Phosphorylation
|
Metabolic Disease
|
Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests .
|
-
- HY-122376
-
D-Trans-Allethrin; Esbiol
|
Sodium Channel
|
Neurological Disease
|
S-Bioallethrin (D-Trans-Allethrin) is a pyrethroid insecticide. S-Bioallethrin disrupts nerve function by modifying the gating kinetics of transitions between the conducting and nonconducting states of voltage-gated sodium channels. S-Bioallethrin also causes inhibition of lymphocyte proliferation and induces histamine release from human basophils .
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-
- HY-151469
-
|
Parasite
|
Others
|
Chitinase-IN-4 (compound 8f), an azo-aminopyrimidine derivative, is a potent, selective OfChi-h inhibitor with an IC50 value of 0.1 μM. Chitinase-IN-4 has good insecticidal activity. Chitinase-IN-4 can be used in research of green pest control and management .
|
-
- HY-121248
-
AC217300
|
Mitochondrial Metabolism
|
Infection
|
Hydramethylnon (AC217300) is an amidinohydrazone insecticide. Hydramethylnon's mechanism of action is through inhibition of mitochondrial respiration by inhibiting the electron transport chain at the cytochrome b-c1 complex. Hydramethylnon can be used to eliminate red imported fire ants, cockroaches, and other insects .
|
-
- HY-133108
-
|
EBV
Parasite
Phosphatase
Influenza Virus
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties .
|
-
- HY-B0827A
-
(R)-MTI-446
|
nAChR
Parasite
|
Infection
|
(R)-Dinotefuran ((R)-MTI-446), a neonicotinoid pesticide, exhibits comparative insecticidal activities (1.7-2.4 times) to typical sucking pests Aphis gossypii and Apolygus lucorum compared to racemic mixtures by inhibiting nicotinic acetylcholine receptors. (R)-Dinotefuran has a good efficacy in controlling target pests while minimizing hazard to honeybees .
|
-
- HY-B2049
-
|
Others
|
Infection
|
Triflumuron is a potent chitin synthesis inhibitor. Triflumuron shows the efficacy in emergence inhibition (EI) against Culex quinquefasciatus and Aedes albopictus, with EI50 values of 5.28 and 1.59 μg/L, respectively. Triflumuron can be used as an insecticide. Triflumuron represents a potential tool for the control of disease vectors in public health .
|
-
- HY-N11706
-
(+)-β-Cedrene
|
Fungal
|
Infection
Inflammation/Immunology
|
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a Ki value of 1.6 μM .
|
-
- HY-B1971R
-
-
- HY-B0836R
-
|
Parasite
Sodium Channel
|
Infection
Neurological Disease
Endocrinology
|
λ-Cyhalothrin (Standard) is the analytical standard of λ-Cyhalothrin. This product is intended for research and analytical applications. λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system .
|
-
- HY-N6693
-
NSC 122023
|
Apoptosis
Antibiotic
Autophagy
Fungal
|
Infection
Others
Cancer
|
Valinomycin is a potassium-specific ionophore, the valinomycin-K + complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K + gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research .
|
-
- HY-B1559
-
|
Apoptosis
|
Cancer
|
Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Allethrin induces BCL-2, caspase-3 activation and release of intracellular calcium .
|
-
- HY-B0840R
-
|
Oxidative Phosphorylation
Parasite
|
Metabolic Disease
|
Chlorfenapyr (Standard) is the analytical standard of Chlorfenapyr. This product is intended for research and analytical applications. Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests .
|
-
- HY-108170
-
|
Parasite
|
Others
|
Pyrethrin II is a insecticidal ingredient of pyrethrins. Pyrethrins is a biogenic insecticide, that can be extracted from Chrysanthemum cinerariifolium .
|
-
- HY-119309
-
|
Biochemical Assay Reagents
|
Others
|
Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers .
|
-
- HY-N3497
-
|
NF-κB
DNA/RNA Synthesis
Parasite
Apoptosis
|
Infection
Cancer
|
Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells . Isochamaejasmin also has a moderate antiplasmodial activity (IC50 of 7.3 μM for P. falciparum) and relatively low cytotoxicity (CC50 of 29.0 μM) .
|
-
- HY-B1315S1
-
|
Parasite
|
Others
|
Carbaryl-d7 is the deuterium labeled Carbaryl[1]. Carbaryl is used chiefly as an insecticide[2].
|
-
- HY-B0833S1
-
|
Isotope-Labeled Compounds
|
Others
|
Thiamethoxam-d3 is the deuterium labeled Thiamethoxam[1]. Thiamethoxam is a broad spectrum neonicotinoid insecticide[2][3].
|
-
- HY-B2049R
-
|
Others
|
Infection
|
Triflumuron (Standard) is the analytical standard of Triflumuron. This product is intended for research and analytical applications. Triflumuron is a potent chitin synthesis inhibitor. Triflumuron shows the efficacy in emergence inhibition (EI) against Culex quinquefasciatus and Aedes albopictus, with EI50 values of 5.28 and 1.59 μg/L, respectively. Triflumuron can be used as an insecticide. Triflumuron represents a potential tool for the control of disease vectors in public health .
|
-
- HY-W042337
-
|
Apoptosis
|
Others
|
3-Methyl-4-nitrophenol, an environmental contaminant, is a well-known constituent of diesel exhaust particles and degradation products of insecticide fenitrothion. 3-Methyl-4-nitrophenol can induce nasal epithelial cell apoptosis and increase the permeability of the nasal epithelial barrier. 3-Methyl-4-nitrophenol is also toxic to the female reproductive system.
|
-
- HY-B0824
-
|
Sodium Channel
|
Neurological Disease
|
Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae (LD50=0.15 ng/mg) and C. quinquefasciatus (LD50=0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material .
|
-
- HY-I1111S1
-
-
- HY-W154397
-
|
Others
|
Infection
|
Permethrinic Acid Methyl Ester is a derivative of the insecticide Permethrin (HY-B0887). Permethrin is an insecticide, an acaricide, and a highly selective inhibitor of mitochondrial complex I .
|
-
- HY-130409
-
-
- HY-B1559R
-
|
Apoptosis
|
Cancer
|
Allethrin (Standard) is the analytical standard of Allethrin. This product is intended for research and analytical applications. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Allethrin induces BCL-2, caspase-3 activation and release of intracellular calcium .
|
-
- HY-119309R
-
|
Biochemical Assay Reagents
|
Others
|
Sucrose octaacetate (Standard) is the analytical standard of Sucrose octaacetate. This product is intended for research and analytical applications. Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers .
|
-
- HY-17524
-
-
- HY-B0824R
-
|
Sodium Channel
|
Neurological Disease
|
Bifenthrin (Standard) is the analytical standard of Bifenthrin. This product is intended for research and analytical applications. Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae (LD50=0.15 ng/mg) and C. quinquefasciatus (LD50=0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material .
|
-
- HY-121618
-
|
GABA Receptor
Reactive Oxygen Species
Parasite
Apoptosis
Autophagy
|
Infection
Neurological Disease
Cancer
|
α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier .
|
-
- HY-119649
-
IKI220
|
Parasite
|
Infection
|
Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues .
|
-
- HY-B2029
-
|
Parasite
|
Infection
|
Phosalone is a member of the organophosphate family of insecticides.
|
-
- HY-B1315
-
-
- HY-122996
-
-
- HY-114680
-
-
- HY-118769
-
|
Parasite
|
Others
|
Japonilure serves as an agent for insecticides and pheromones.
|
-
- HY-124495
-
|
Parasite
|
Others
|
Butocarboxime serves as both an insecticide and acaricide.
|
-
- HY-148964
-
HY366
|
Others
|
Others
|
Thiotraniliprole (HY366) is an ortho formamidobenzamide insecticide that can be used for the synthesis of insecticidal combinations. Thiotraniliprole has potential applications in the prevention of lepidoptera pests, coleoptera pests, ants, and termites .
|
-
- HY-B1331
-
Cyromazin; CGA-72662
|
Endogenous Metabolite
Parasite
|
Neurological Disease
Metabolic Disease
|
Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats .
|
-
- HY-W654238
-
|
Isotope-Labeled Compounds
Others
|
Others
|
Imidaclothiz-d4 is deuterium labeled Imidaclothiz. Imidaclothiz is a kind of neonicotinoid insecticides. Imidaclothiz has excellent insecticidal effect. Imidaclothiz can be used for the research of sucking and biting insects .
|
-
- HY-17516
-
|
Bacterial
|
Others
|
Tolfenpyrad is an insecticide approved for marketing in Japan in 2002.
|
-
- HY-17523
-
GS-13006
|
Others
|
Infection
|
Athidathion(GS-13006) is an organophosphate insecticide.
|
-
- HY-117097
-
Bay 16574
|
Others
|
Others
|
Bayer 16574 is an insecticide for stored-goods pests.
|
-
- HY-118428
-
M2060; TH 367-1
|
Others
|
Others
|
Fluenetil (M2060) is a compound with insecticidal activity.
|
-
- HY-121768
-
|
Parasite
|
Others
|
Trimethacarb is a type of insecticide used for pest control.
|
-
- HY-B1973S
-
|
Isotope-Labeled Compounds
|
Others
|
Diflubenzuron-d4 is the deuterium labeled Diflubenzuron[1]. Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities[2][3].
|
-
- HY-118322
-
|
Others
|
Others
|
Bayer 30468 is an insecticide that is toxic to adult boll weevils.
|
-
- HY-119556
-
|
Parasite
|
Infection
|
Butonate is an insecticide. Butonate is an orally active anthelmintic .
|
-
- HY-12643
-
-
- HY-116448
-
-
- HY-129257
-
|
Others
|
Others
|
Esfenvalerate is one of the four isomers of the pyrethroid insecticide fenvalerate .
|
-
- HY-130423
-
|
Others
|
Others
|
Milbemycin A3 is an insecticide with acaricidal and nematocidal activities .
|
-
- HY-N14120
-
Opopanax oil
|
Others
|
Others
|
Opoponax oil is an effective insecticide against mosquito larvae .
|
-
- HY-B1331R
-
|
Endogenous Metabolite
Parasite
|
Neurological Disease
Metabolic Disease
|
Cyromazine (Standard) is the analytical standard of Cyromazine. This product is intended for research and analytical applications. Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats .
|
-
- HY-N1418
-
(-)-Canadine; (S)-(-)-Canadine
|
Others
|
Inflammation/Immunology
|
(S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity .
|
-
- HY-119649R
-
|
Parasite
|
Infection
|
Flonicamid (Standard) is the analytical standard of Flonicamid. This product is intended for research and analytical applications. Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues .
|
-
- HY-W040149
-
|
Others
|
Others
|
Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests .
|
-
- HY-B0767
-
|
Others
|
Others
|
Spinosyn A, a polyketide-derived macrolide produced by Saccharopolyspora spinosa, is a potent insecticide .
|
-
- HY-119525
-
|
Others
|
Infection
|
Propetamphos is an organophosphorus insecticide. Propetamphos causes cytotoxicity and oxidative stress .
|
-
- HY-N12093
-
-
- HY-119438
-
|
Others
|
Others
|
Aspon is an organophosphorus insecticide. Aspon can be utilized as phosphorus sources by bacteria .
|
-
- HY-W923487
-
|
Others
|
Others
|
(Rac)-Bifenthrin is a pyrethroid insecticide commonly utilized in both urban and agricultural settings.
|
-
- HY-12643R
-
MK-397 (Standard)
|
Parasite
Bacterial
Reactive Oxygen Species
β-catenin
Apoptosis
Autophagy
|
Infection
Cancer
|
Eprinomectin (Standard) is the analytical standard of Eprinomectin. This product is intended for research and analytical applications. Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity .
|
-
- HY-N8484
-
|
Parasite
|
Infection
|
Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.
|
-
- HY-17533
-
ANS118
|
Others
|
Others
|
Chromafenozide (ANS118) is a lepidopteran insecticide; it is highly effective in controlling various lepidopteran pests.
|
-
- HY-B1113
-
Dimpylate
|
Parasite
|
Infection
|
Diazinon is a thiophosphoric acid ester, is a nonsystemic organophosphate insecticide, used to control cockroaches, silverfish, ants, and fleas.
|
-
- HY-101417
-
Diethyl phosphoric acid
|
Endogenous Metabolite
|
Others
|
Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos .
|
-
- HY-12779S
-
-
- HY-B0887D
-
(-)-cis-NRDC-143
|
Others
|
Others
|
(-)-cis-Permethrin is a pyrethroid insecticide widely used to control many common pests .
|
-
- HY-111742
-
|
Drug Metabolite
|
Others
|
Bifenazate-diazene is a major degradation product of Bifenazate. Bifenazate is a selective carbazate acaricide and an insecticide .
|
-
- HY-123178
-
|
Others
|
Neurological Disease
|
Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively .
|
-
- HY-W588212
-
trans-NRDC-143
|
Parasite
|
Neurological Disease
|
trans-Permethrin is a transconfiguration of Permethrin (HY-B0887). Permethrin is an insecticide and neurotoxin .
|
-
- HY-118412
-
M108
|
Parasite
|
Infection
|
Terallethrin (M108) is a synthetic pyrethroid widely used as an insecticide in agricultural and household Settings .
|
-
- HY-17530
-
|
Cholinesterase (ChE)
|
Others
|
Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.
|
-
- HY-164052
-
|
Parasite
|
Infection
|
Antiparasitic agent-23 (compound 14) is an anthelmintic and insecticide that inhibits insect or helminth parasitism .
|
-
- HY-120002
-
Kilacar; R 8284
|
Parasite
|
Infection
|
Proclonol (Kilacar) is an insecticide-acaricide. Proclonol is a weak mutagen in the TA97 strain of S. typhimurium .
|
-
- HY-118926
-
|
Parasite
|
Others
|
Bioresmethrin is an insecticide that protects grain. Bioresmethrin against malathion-resistant and susceptible strains R. dominica .
|
-
- HY-12643S
-
MK-397-d3
|
Isotope-Labeled Compounds
|
Infection
Cancer
|
Eprinomectin-d3 (MK-397-d3) is the deuterium-labeled Eprinomectin (HY-12643). Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity .
|
-
- HY-17519
-
|
Others
|
Infection
|
Novaluron is a chemical with insecticide properties, an insect growth regulator, and has adverse effects on mouse sperm .
|
-
- HY-16973
-
A1443; AH252723
|
Parasite
|
Infection
|
Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
|
-
- HY-N3507
-
|
Others
|
Others
|
Euojaponine D is a sesquiterpene alkaloids from Euonymus japonica (Celastraceae). Celastraceae has potent insecticidal activity .
|
-
- HY-B0874
-
FMC 45497; Fendona; WL 85871
|
Others
|
Others
|
Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is an effective insecticide against house flies .
|
-
- HY-B1885S
-
|
Isotope-Labeled Compounds
Cholinesterase (ChE)
|
Infection
|
Fenitrothion-d6 is the deuterium labeled Fenitrothion[1]. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols[2][3].
|
-
- HY-160758
-
|
Others
|
Others
|
J9Z38 is a metabolite of Cyantraniliprole (HY-12779), a broad-spectrum agrochemical insecticide belonging to the anthranilic diamide insecticide class. Cyantraniliprole effectively controls the growth of various pests on fruits, vegetables, cereals and other crops. Thus, J9Z38 is a key indicator for indirect detection and evaluation of Cyantraniliprole residue levels .
|
-
- HY-N3076
-
(-)-Phyllostine; Phyllostin
|
Others
|
Others
|
Phyllostine ((-)-Phyllostine) can be isolated from D. miriciae. Phyllostine exhibits strong antifeedant, contact toxicity, and oviposition deterrent activities against P. xylostella .
|
-
- HY-W020785
-
|
Cholinesterase (ChE)
|
Others
|
Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase .
|
-
- HY-W020785R
-
|
Cholinesterase (ChE)
|
Others
|
Fosthiazate (Standard) is the analytical standard of Fosthiazate. This product is intended for research and analytical applications. Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase .
|
-
- HY-B0916
-
|
Fungal
|
Infection
|
Propoxur is a carbamate insecticide with a fast knockdown and long residual effect used against turf, forestry, and household pests and fleas.
|
-
- HY-122551
-
|
Others
|
Others
|
Chlorfenethol is a dehydrochlorinase inhibitor. Chlorfenethol can be used as a synergist for insecticide DDT to increase its effect on resistant strains .
|
-
- HY-B1315R
-
|
Parasite
|
Others
|
Carbaryl (Standard) is the analytical standard of Carbaryl. This product is intended for research and analytical applications. Carbaryl is used chiefly as an insecticide .
|
-
- HY-B0827
-
MTI-446
|
nAChR
Parasite
|
Infection
|
Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
|
-
- HY-N6689
-
|
Antibiotic
|
Infection
Cancer
|
Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities .
|
-
- HY-116448S
-
-
- HY-121745
-
Imidoxon; Oxoimidan
|
Drug Metabolite
|
Infection
|
Phosmet oxon (Imidoxon) is a main and toxic metabolite of phosmet. Phosmet is a cholinesterase inhibitor insecticide used on pome and stone fruits .
|
-
- HY-N1304
-
Shyobunon
|
Others
|
Others
|
Shyobunone (Shyobunon) is a nature product that could be isolated from Acorus calamus rhizomes. Shyobunone has insecticidal and repellant activity .
|
-
- HY-133216
-
|
Fungal
|
Infection
|
Bupirimate possesses antifungal activity. Bupirimate is compatible with most of fungicides, insecticides and adjuvants, with very limited exceptions on some crops .
|
-
- HY-126872
-
|
Antibiotic
Fungal
|
Infection
|
Nikkomycin I is a nucleoside peptide antibiotic found in Streptomyces tendae of the genus Streptomyces, with high antifungal, insecticidal, and acaricidal activities .
|
-
- HY-17516R
-
|
Bacterial
|
Others
|
Tolfenpyrad (Standard) is the analytical standard of Tolfenpyrad. This product is intended for research and analytical applications. Tolfenpyrad is an insecticide approved for marketing in Japan in 2002.
|
-
- HY-114614
-
|
Parasite
|
Infection
|
Clenpirin is a insecticide against cattle ticks Boophilus microplus. Clenpirin exhibits slightly toxicity to rats with LD50 of 3050 mg/kg .
|
-
- HY-Y1887
-
|
Biochemical Assay Reagents
|
Others
|
Cottonseed oil is a cooking oil extracted from the seeds of cotton plants and has been generally considered the most insecticidal of vegetable oils.
|
-
- HY-116702
-
|
GABA Receptor
|
Others
|
Flufiprole is a nonsystemic phenylpyrazole insecticide targeting the GABA receptor used in the rice field. Flufiprole is excellent in controlling a wide range of pests .
|
-
- HY-137445
-
|
Parasite
|
Infection
|
Modoflaner is an isophenylamide insecticide. Modoflaner may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels .
|
-
- HY-114502
-
NSC 11779
|
Others
|
Others
|
Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others .
|
-
- HY-B0833R
-
|
Others
|
Others
|
Thiamethoxam (Standard) is the analytical standard of Thiamethoxam. This product is intended for research and analytical applications. Thiamethoxam is a broad spectrum neonicotinoid insecticide .
|
-
- HY-162778
-
|
Parasite
|
Infection
|
FM-1088 is an insecticide. FM-1088 can be used in research related to crop disease and insect pest control .
|
-
- HY-B0826
-
BAJ-2740
|
Parasite
|
Infection
|
Spirodiclofen is a broad spectrum acaricide acting via lipid biosynthesis inhibition (LBI) with no cross resistance to currently available acaricides and with additional insecticidal properties.
|
-
- HY-108690
-
|
GABA Receptor
|
Others
|
Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls.
|
-
- HY-111634
-
|
Constitutive Androstane Receptor
|
Cancer
|
Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide, activates constitutive androstane receptor (CAR), and induces hepatocellular tumors in rats .
|
-
- HY-N0263
-
|
Others
|
Inflammation/Immunology
|
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .
|
-
- HY-B2009
-
|
Others
|
Others
|
Flufenoxuron is a chitin synthesis inhibitor that is used as a benzoylurea insecticide. Flufenoxuron decreases chitin synthesis, molting, and egg hatching, preventing development in insects .
|
-
- HY-W075176
-
|
Others
|
Others
|
Transfluthrin is a fast-acting pyrethroid insecticide and mosquito repellent. Transfluthrin is against flying insects, such as mosquito and flies, and in agriculture material pests .
|
-
- HY-134338
-
|
Parasite
|
Others
|
Ipflufenoquin is an insecticide with the potential to control primary infection with apple scab. Ipflufenoquin should be applied between half an inch of green and fruit set .
|
-
- HY-116448R
-
BAS-320I (Standard)
|
Sodium Channel
Parasite
|
Infection
|
Metaflumizone (Standard) is the analytical standard of Metaflumizone. This product is intended for research and analytical applications. Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker .
|
-
- HY-114720
-
|
Others
|
Others
|
Laureatin is an active product that can be isolated from the marine algae Laurencia nipponica. Laureatin exhibits potent insecticidal activity against mosquitos .
|
-
- HY-129257R
-
|
Others
|
Others
|
Esfenvalerate (Standard) is the analytical standard of Esfenvalerate. This product is intended for research and analytical applications. Esfenvalerate is one of the four isomers of the pyrethroid insecticide fenvalerate .
|
-
- HY-125040
-
-
- HY-164322
-
|
GABA Receptor
|
Others
|
Cyproflanilide is an insecticide. Cyproflanilide is a GABAR antagonist. Cyproflanilide shows high activity against a variety of pests, including lepidopteran, coleopteran, and thysanopteran pests .
|
-
- HY-107034
-
349C59
|
Parasite
|
Infection
|
Moxipraquine is a potent insecticide against Trypanosoma cruzi. Moxipraquine effectively inhibits Leishmania major, L. mexicana mexicana and L. brasiliensis panamensis but not L.b. brasiliensis .
|
-
- HY-N10682
-
|
Others
|
Others
|
Hypoglaunine A is a sesquiterpene pyridine alkaloid isolated from the bark of the roots of Tripterygium hypoglaucum, a traditional Chinese medicine often used as a cancer and insecticide research .
|
-
- HY-B0887C
-
1R-cis-NRDC-143
|
Parasite
|
Infection
|
1R-cis-Permethrin is an insecticide and neurotoxin. 1R-cis-Permethrin affects neuron membranes by prolonging sodium channel activation .
|
-
- HY-W585834
-
|
Others
|
Others
|
Fipronil desulfinyl is a photodegradation product of the insecticide Fipronil (HY-B0822) and has similar in vivo toxicity to Fipronil but higher environmental pollution .
|
-
- HY-W040149R
-
|
Others
|
Others
|
Tetramethrin (Standard) is the analytical standard of Tetramethrin. This product is intended for research and analytical applications. Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests .
|
-
- HY-119902
-
|
Others
|
Cardiovascular Disease
|
Bistrifluron has insecticidal effects on the larval stage, and also has an effect on adult longevity, reproduction, and hatchability. Bistrifluron is used for the control of a variety of Lepidopterous pests .
|
-
- HY-B1161
-
Methoprene
Maximum Cited Publications
11 Publications Verification
ZR-515
|
Others
|
Others
|
Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist .
|
-
- HY-123178S
-
|
Isotope-Labeled Compounds
|
Neurological Disease
|
Fenpropathrin-d5 is the deuterium labeled Fenpropathrin. Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively[1].
|
-
- HY-W018171
-
TCPy
|
Others
|
Others
|
3,5,6-Trichloro-2-pyridinol (TCPy) is the main degradation product of the herbicide Triclopyr and the insecticides Chlorpyrifos and Chlorpyrifos-methyl .
|
-
- HY-126021
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Mobam is a insecticide against Anoplura Pediculidae. Mobam inhibits cholinesterase (ChE) levels in rats plasma, erythrocytes, and brain, suppresses the avoidance behavior in rats .
|
-
- HY-119525R
-
|
Others
|
Infection
|
Propetamphos (Standard) is the analytical standard of Propetamphos. This product is intended for research and analytical applications. Propetamphos is an organophosphorus insecticide. Propetamphos causes cytotoxicity and oxidative stress .
|
-
- HY-169008
-
|
PROTACs
Acetyl-CoA Carboxylase
|
Infection
|
PROTAC ACC degrader-1 (Compound 9b) is a Acetyl-CoA Carboxylase degrader. PROTAC ACC degrader-1 exhibits superior potency against Aphis craccivora (IC50 = 107.8 μg/mL). (Structure Note: Pink, Target protein ligand (HY-169009); Blue, E3 ligand (HY-10984); Black, linker (HY-W007559) .
|
-
- HY-W009165
-
cis-9-Tricosene
|
Others
|
Others
|
(Z)-9-Tricosene (cis-9-Tricosene) is an insect pheromone present in flies of the order Diptera (such as the housefly) and can be used as an insecticide .
|
-
- HY-W013767
-
|
Others
|
Infection
|
Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile .
|
-
- HY-137801
-
|
Parasite
|
Infection
|
Sesquicillin A is an insecticidal antibiotic, a fungal metabolite isolated from white plantain. Sesquicillin A inhibits the growth of A. salina brine shrimp with the MIC value of 6.25 µg/mL .
|
-
- HY-B2006
-
|
Phosphatase
Bacterial
|
Infection
|
Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide .
|
-
- HY-B0841S
-
-
- HY-101417S1
-
Diethyl phosphoric acid-d10
|
Endogenous Metabolite
|
Others
|
Diethyl phosphate-d10-1 is the deuterium labeled Diethyl phosphate[1]. Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos.
|
-
- HY-N1418A
-
(+)-Canadine; (R)-(+)-Canadine
|
Others
|
Inflammation/Immunology
|
(R)-(+)-Tetrahydroberberine is the isomer of (S)-(-)-Tetrahydroberberine (HY-N1418), and can be used as an experimental control. (S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity .
|
-
- HY-123178R
-
|
Others
|
Neurological Disease
|
Fenpropathrin (Standard) is the analytical standard of Fenpropathrin. This product is intended for research and analytical applications. Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively .
|
-
- HY-130423R
-
|
Others
|
Others
|
Milbemycin A3 (Standard) is the analytical standard of Milbemycin A3. This product is intended for research and analytical applications. Milbemycin A3 is an insecticide with acaricidal and nematocidal activities .
|
-
- HY-W341259
-
|
Parasite
|
Infection
|
Isazofos is a broad-spectrum organophosphate insecticide-nematicide that controls numerous pests of turf, such as nematode Radopholus similis. Isazofos is also effective in the control of rice gall midge .
|
-
- HY-B1111
-
-
- HY-B0887S1
-
NRDC-143-d9
|
Isotope-Labeled Compounds
Parasite
|
Infection
|
Permethrin-d9 is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
|
-
- HY-N11761
-
|
Parasite
|
Infection
|
4,5-Dihydropiperlonguminine is a natural product that can be isolated from the seeds of Piper tuberculatum Jacq. (Piperaceae). 4,5-Dihydropiperlonguminine is a insecticide against velvetbean caterpillars .
|
-
- HY-16973R
-
|
Parasite
|
Infection
|
Fluralaner (Standard) is the analytical standard of Fluralaner. This product is intended for research and analytical applications. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
|
-
- HY-B0820
-
|
nAChR
Parasite
|
Neurological Disease
|
Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals .
|
-
- HY-126906
-
|
Antibiotic
P-glycoprotein
|
Cancer
|
Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity sup>[2].
|
-
- HY-155252
-
(-)-Spinosyn A aglycon
|
Others
|
Others
|
Spinosyn A aglycone ((-)-Spinosyn A aglycon) is an aglycone form of the insecticide Spinosyn A (HY-B0767). Spinosyn A aglycone is an acid degradation product produced by hydrolysis of both saccharide groups on spinosyn A .
|
-
- HY-119141
-
|
Sodium Channel
|
Neurological Disease
|
RH 3421, an insecticidal dihydropyrazole, acts as an inhibitor of sodium channel-specific sodium uptake, blocking the uptake stimulated by Veratridine (HY-N6691), Vatrachotoxin (HY-12549), crude scorpion .
|
-
- HY-167244
-
|
Others
|
Others
|
AI 3-23445 is a compound with environmental toxicity and insecticidal activity, capable of inducing avoidance behavior in Peromyscus maniculatus and Mus musculus. AI 3-23445 can be utilized in agricultural research .
|
-
- HY-W115752
-
Diamine sulfate (99%)
|
Biochemical Assay Reagents
|
Others
|
Hydrazine sulfate (99%) (Diamine sulfate (99%)) is used as an insecticide, sterilant, and plant growth inhibitor in agriculture. Hydrazine sulfate (99%) is a biomaterial or organic compound that can be used in life science research .
|
-
- HY-Y0946S
-
|
Isotope-Labeled Compounds
|
Cancer
|
Acetamide- 15N is the 15N-labeled Acetamide. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[1][2].
|
-
- HY-N7144A
-
|
Apoptosis
|
Infection
Cancer
|
Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects .
|
-
- HY-108689
-
|
GABA Receptor
|
Neurological Disease
|
Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM .
|
-
- HY-W016433
-
|
DNA/RNA Synthesis
|
Others
|
2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis .
|
-
- HY-114373
-
|
Parasite
|
Infection
|
Calarene is an insecticide that can be obtained from the stem of Kadsura heteroclite. Calarene is toxic to Meloidogyne incognita, Sitophilus zeamais, and mosquitoes. Calarene can be used in the research of plant pests and mosquito control .
|
-
- HY-N12210
-
|
Parasite
|
Others
|
Notrilobolide is an alkaloid with insecticidal properties isolated from sweet potatoes. Notrilobolide has an inhibitory effect on the larval development of pests such as Tribolium Castaneum, affecting the digestion and reproduction of insects by inhibiting the fecundity of pests .
|
-
- HY-155387
-
|
Others
|
Others
|
ZK-PI-5 is a potent trehalase inhibitor and regulate the reproduction of Spodoptera frugiperda. ZK-PI-5 has the potential to be a?new insecticide and has pest control potential .
|
-
- HY-126744
-
|
Others
|
Others
|
Juncin E is a diterpenoid found in the soft coral Junceella juncea that exhibits significant insecticidal activity against the larvae of two important agricultural pests: southern corn rootworm and tobacco armyworm [2].
|
-
- HY-B1971S
-
Decamethrin-d5
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
Deltamethrin-d5 is the deuterium labeled Deltamethrin. Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis[1][2].
|
-
- HY-Y0055S
-
|
Antibiotic
Fungal
Bacterial
|
Infection
Neurological Disease
|
Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].
|
-
- HY-W127474
-
|
Biochemical Assay Reagents
|
Others
|
Ethyl pentadecanoate is an organic compound that is commonly used as a flavoring and food additive, and can also be used in industrial manufacturing, such as the production of lubricants and surfactants. In addition, Ethyl pentadecanoate has biological activities such as antibacterial, insecticidal and antiseptic.
|
-
- HY-Y0946S2
-
|
Isotope-Labeled Compounds
|
Cancer
|
Acetamide-d5 is the deuterium labeled Acetamide[1]. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[2][3].
|
-
- HY-119779
-
S 1812
|
Others
|
Others
|
Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management .
|
-
- HY-B0887R
-
|
Parasite
Mitochondrial Metabolism
|
Infection
Neurological Disease
|
Permethrin (Standard) is the analytical standard of Permethrin. This product is intended for research and analytical applications. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
|
-
- HY-133216R
-
|
Fungal
|
Infection
|
Bupirimate (Standard) is the analytical standard of Bupirimate. This product is intended for research and analytical applications. Bupirimate possesses antifungal activity. Bupirimate is compatible with most of fungicides, insecticides and adjuvants, with very limited exceptions on some crops .
|
-
- HY-169068
-
|
Carboxylesterase
|
Infection
|
Antifeedant agent 1 is a carboxylesterase inhibitor that exerts insecticidal activity by inhibiting insect feeding, with an EC50 value of 0.038 mg/mL. Antifeedant agent 1 can be used in research related to pest control .
|
-
- HY-W488109
-
|
Others
|
|
Genite is a highly effective pesticide with strong insecticidal activity. Genite can effectively control the number of various pests and is widely used in agricultural production. The use of Genite can significantly increase the yield and quality of crops.
|
-
- HY-B0827S
-
MTI-446-d3
|
nAChR
Parasite
|
Infection
|
Dinotefuran-d3 is the deuterium labeled Dinotefuran[1]. Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors[2].
|
-
- HY-118751
-
Bancol
|
nAChR
|
Others
Neurological Disease
|
Bensultap (Bancol) is an insecticide, which can control Colorado beetle and some other insect pests. Bensultap is a modulator for nicotinic acetylcholine receptor (nAChR), and exhibits mild and temporary neuromodulatory efficacy on rat nervous system .
|
-
- HY-W778140
-
|
Isotope-Labeled Compounds
Bacterial
Parasite
|
Infection
|
Diethyl phosphate- 13C4 (sodium) is the 13C labeled isotope of Diethyl phosphate- 13C4 (sodium)(HY-101417).Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos .
|
-
- HY-114633
-
|
Potassium Channel
|
Others
|
VU625 is an inhibitor for potassium channel, that selectively inhibits mosquito Aedes aegypti inward rectifier potassium channel 1 (AeKir), with IC50 of 96.8 nM in HEK293 cell. VU625 can be used in development of insecticide .
|
-
- HY-B2054
-
|
Apoptosis
|
Others
|
Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
|
-
- HY-17518
-
IR5885; Valiphenal
|
Bacterial
|
Others
|
Valifenalate(IR5885; Valiphenal), which is approved for application on high-value crops such as grapes, tomatoes and other vegetables, is effective against various types of mildew and is currently marketed primarily under the Valis moniker; insecticide agent.
|
-
- HY-B1331S
-
|
Endogenous Metabolite
|
Neurological Disease
|
Cyromazine-d4 is the deuterium labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
|
-
- HY-B1111S1
-
-
- HY-116883
-
|
Biochemical Assay Reagents
|
Others
|
Endothion, a systemic insecticide, has been used for agricultural and horticultural areas. Endothion can prevent Mediterranean Drosophila on peaches, and the residual effect lasts for more than 3 weeks without toxicity to leaves and fruits .
|
-
- HY-B2009R
-
|
Others
|
Others
|
Flufenoxuron (Standard) is the analytical standard of Flufenoxuron. This product is intended for research and analytical applications. Flufenoxuron is a chitin synthesis inhibitor that is used as a benzoylurea insecticide. Flufenoxuron decreases chitin synthesis, molting, and egg hatching, preventing development in insects .
|
-
- HY-121745R
-
|
Drug Metabolite
|
Infection
|
Phosmet oxon (Standard) is the analytical standard of Phosmet oxon. This product is intended for research and analytical applications. Phosmet oxon (Imidoxon) is a main and toxic metabolite of phosmet. Phosmet is a cholinesterase inhibitor insecticide used on pome and stone fruits .
|
-
- HY-B0874R
-
|
Others
|
Others
|
Alpha-Cypermethrin (Standard) is the analytical standard of Alpha-Cypermethrin. This product is intended for research and analytical applications. Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is an effective insecticide against house flies .
|
-
- HY-W075176R
-
|
Others
|
Others
|
Transfluthrin (Standard) is the analytical standard of Transfluthrin. This product is intended for research and analytical applications. Transfluthrin is a fast-acting pyrethroid insecticide and mosquito repellent. Transfluthrin is against flying insects, such as mosquito and flies, and in agriculture material pests .
|
-
- HY-137970
-
A-83543D aglycone
|
Parasite
|
Infection
|
Spinosyn D aglycone is an aglycone form of the insecticide Spinosyn D (HY-125326). Unlike spinosyn D, spinosyn D aglycone is not lethal to H. virescens (tobacco budworm) neonate larvae (LC50=>64 ppm).
|
-
- HY-115584S
-
|
Isotope-Labeled Compounds
Parasite
|
Infection
|
Lufenuron- 13C6 is a 13C-labeled Lufenuron. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods[1][2].
|
-
- HY-N12131
-
|
Others
|
Metabolic Disease
|
Ejaponine A (Compound 1) is an insecticidal sesquiterpene ester. Ejaponine A is obtained from the natural Euonymus japonicus. Ejaponine A has Mythimna separata killing activity (LD5089.2 μgg -1). Ejaponine A is used to kill Mythimna separata .
|
-
- HY-B2006S
-
|
Phosphatase
Bacterial
|
Infection
|
Fenvalerate-d5 is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1].
|
-
- HY-B1331S1
-
Cyromazin-13C3; CGA-72662-13C3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
|
Cyromazine- 13C3 is the 13C3 labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
|
-
- HY-B1161S
-
ZR-515-d7
|
Isotope-Labeled Compounds
|
Others
|
Methoprene-d7 is the deuterium labeled Methoprene[1]. Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist[2][3].
|
-
- HY-B1161R
-
|
Others
|
Others
|
Methoprene (Standard) is the analytical standard of Methoprene. This product is intended for research and analytical applications. Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist .
|
-
- HY-119902R
-
|
Others
|
Cardiovascular Disease
|
Bistrifluron (Standard) is the analytical standard of Bistrifluron. This product is intended for research and analytical applications. Bistrifluron has insecticidal effects on the larval stage, and also has an effect on adult longevity, reproduction, and hatchability. Bistrifluron is used for the control of a variety of Lepidopterous pests .
|
-
- HY-16973S
-
A1443-13C2,15N,d3; AH252723-13C2,15N,d3
|
Isotope-Labeled Compounds
Parasite
|
Infection
|
Fluralaner- 13C2, 15N,d3 is the deuterium, 13C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
|
-
- HY-W127493
-
Ceryl Alcohol
|
Biochemical Assay Reagents
|
Infection
|
1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
|
-
- HY-B1111R
-
|
Adrenergic Receptor
Monoamine Oxidase
Parasite
|
Infection
Endocrinology
|
Amitraz (Standard) is the analytical standard of Amitraz. This product is intended for research and analytical applications. Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis.
|
-
- HY-W013767R
-
|
Others
|
Infection
|
Thiodicarb (Standard) is the analytical standard of Thiodicarb. This product is intended for research and analytical applications. Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile .
|
-
- HY-W585834R
-
|
Others
|
Others
|
Fipronil desulfinyl (Standard) is the analytical standard of Fipronil desulfinyl. This product is intended for research and analytical applications. Fipronil desulfinyl is a photodegradation product of the insecticide Fipronil (HY-B0822) and has similar in vivo toxicity to Fipronil but higher environmental pollution .
|
-
- HY-B0815
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Chlorpyrifos is a neurotoxic insecticide that belongs to the class of thionite esters. Chlorpyrifos is also a AChE inhibitor that affects neurological function in insects, humans and other animals. Chlorpyrifos interferes with cell replication and differentiation, ultimately altering synaptic transmission in neurons .
|
-
- HY-W004520
-
5-Methylphenazinium methylsulfate
|
Bacterial
Antibiotic
Apoptosis
|
Cancer
|
Phenazine methylsulfate is a free radical generator that can act as an electron transfer reactant in cell viability assays. It also has insecticidal properties. Furthermore, Phenazine methylsulfate induces oxidative DNA damage and cell apoptosis, showing antitumor activity .
|
-
- HY-126383
-
|
Bacterial
|
Infection
Others
Inflammation/Immunology
Cancer
|
Spilanthol is an orally active analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial and insecticidal compound.pilanthol can induce cAMP to inhibit negative regulation of urinary concentration mechanism. Spilanthol can be use as diuretic research .
|
-
- HY-B2006R
-
|
Phosphatase
Bacterial
|
Infection
|
Fenvalerate (Standard) is the analytical standard of Fenvalerate. This product is intended for research and analytical applications. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide .
|
-
- HY-P3100
-
|
Parasite
|
Infection
|
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
|
-
- HY-B0887S
-
NRDC-143-d5
|
Parasite
|
Infection
|
Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].
|
-
- HY-119381
-
Jodfenphos
|
Others
|
Others
|
Iodofenphos (Jodfenphos) is an insecticide, that can be used as a protectant for stored grains. Iodofenphos is effective against grain pests, such as Sitophilus oryzae, Tribolium castaneum, and larvae of Trogoderma granarium, and has a significant residual toxicity, which could provide good insect control for several months .
|
-
- HY-136395
-
|
Reactive Oxygen Species
|
Infection
|
Cartap, an organonitrogen insecticide, can cause a marked irreversible Ca 2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms. Cartap significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells .
|
-
- HY-W040028
-
|
Reactive Oxygen Species
|
Infection
|
Cartap hydrochloride, an organonitrogen insecticide, can cause a marked irreversible Ca 2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms. Cartap hydrochloride significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells .
|
-
- HY-B0820R
-
|
nAChR
Parasite
|
Neurological Disease
|
Nitenpyram (Standard) is the analytical standard of Nitenpyram. This product is intended for research and analytical applications. Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals .
|
-
- HY-112785
-
|
Parasite
|
|
Pyriftalid is a new type of insecticide with strong inhibitory activity against a variety of pests. Pyriftalid is widely used in agriculture to effectively control pests on crops, thereby improving crop yield and quality. Pyriftalid is also being studied for improving plant resistance to resist attacks by pests and diseases.
|
-
- HY-B2055
-
|
Others
|
Others
|
Teflubenzuron is a chitin synthesis inhibitor used as a biocide. Teflubenzuron is toxic for F. candida .
|
-
- HY-163662
-
-
- HY-W753602
-
|
Isotope-Labeled Compounds
|
Neurological Disease
|
Acetamiprid-N-desmethyl- 13C,d3 is the 13C and deuterium labeled isotope of Acetamiprid-N-desmethyl( 13C,d3)(HY-B0823).Acetamiprid is a nAChR agonist that has been implicated in neuromuscular and reproductive disorders.
|
-
- HY-B2055R
-
|
Others
|
Others
|
Teflubenzuron (Standard) is the analytical standard of Teflubenzuron. This product is intended for research and analytical applications. Teflubenzuron is a chitin synthesis inhibitor used as a biocide. Teflubenzuron is toxic for F. candida .
|
-
- HY-120425
-
|
Others
|
Infection
|
Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity .
|
-
- HY-B1111S
-
-
- HY-N7144AR
-
|
Apoptosis
|
Infection
Cancer
|
Citronellyl acetate (Standard) is the analytical standard of Citronellyl acetate. This product is intended for research and analytical applications. Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects .
|
-
- HY-108689R
-
|
GABA Receptor
|
Neurological Disease
|
Broflanilide (Standard) is the analytical standard of Broflanilide. This product is intended for research and analytical applications. Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM .
|
-
- HY-B2021
-
|
Others
|
|
τ-Fluvalinate is a broad-spectrum insecticide that is effective against a wide range of insect pests. τ-Fluvalinate is widely used in agriculture to protect crops from insects. The mechanism of τ-Fluvalinate is mainly through interfering with the nervous system of the pest, leading to its death.
|
-
- HY-I1111S2
-
-
- HY-114501
-
|
Parasite
|
Endocrinology
|
Z3-Dodecenyl E2-butenoate is a female sex pheromone produced by the sweet potato weevil, C. formicarius. It has been used to bait and trap male sweet potato weevils to manage population counts in agriculture fields with reduced use of insecticides.
|
-
- HY-112820
-
|
Calcium Channel
Others
|
Others
|
Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ~300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
|
-
- HY-Y0946
-
|
Biochemical Assay Reagents
|
Inflammation/Immunology
Cancer
|
Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies .
|
-
- HY-B1837A
-
beta-Cyfluthrin
|
Calcium Channel
|
Neurological Disease
|
β-Cyfluthrin (beta-Cyfluthrin) is a type II synthetic pyrethroid and also an active ingredient of many insecticide products used for pestsin agriculture. β-Cyfluthrin is a neurotoxicant and affects calcium concentration in nervous tissue by inhibiting Ca 2+ ATPase involved in calcium transport .
|
-
- HY-119779R
-
|
Others
|
Others
|
Pyridalyl (Standard) is the analytical standard of Pyridalyl. This product is intended for research and analytical applications. Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management .
|
-
- HY-126906R
-
|
Antibiotic
P-glycoprotein
|
Cancer
|
Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity sup> .
|
-
- HY-B1946S
-
|
Isotope-Labeled Compounds
|
Others
|
Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects[1].
|
-
- HY-N2534
-
-
- HY-B1953S
-
|
DNA Stain
Parasite
|
Infection
|
Thiacloprid-d4 is the deuterium labeled Thiacloprid[1]. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].
|
-
- HY-118839
-
|
Endogenous Metabolite
|
Infection
|
Trans-Phenothrin is a synthetic pyrethroid with activity against adult fleas and ticks. Trans-Phenothrin has shown significant differences in biological activity between its different enantiomers in comparison with fenvalerate and d-trans-phenothrin. Trans-Phenothrin is used in agriculture for its potential insecticide activity against pests such as Plutella xylostella .
|
-
- HY-N1487
-
3-Oxooleanolic acid
|
HIV
Autophagy
Ferroptosis
Amyloid-β
|
Infection
Neurological Disease
Inflammation/Immunology
Cancer
|
Oleanonic acid (3-Oxooleanolic acid) is an orally available triterpene that has anti-inflammatory and insecticidal properties. In vitro, oleanonic acid can improve oxidative stress, autophagy defects, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress induced by Amyloid-β, and in vivo, it can alleviate myocardial hypertrophy in rats .
|
-
- HY-B1881S
-
|
Isotope-Labeled Compounds
Parasite
Cholinesterase (ChE)
|
Infection
|
Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains[1][2][3].
|
-
- HY-B0816
-
|
Others
|
Others
Cancer
|
Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
|
-
- HY-W016433S
-
|
DNA/RNA Synthesis
|
Others
|
2-Aminofluorene- 13C is the 13C labeled 2-Aminofluorene[1]. 2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[2][3][4].
|
-
- HY-W016433S1
-
|
DNA/RNA Synthesis
|
Others
|
2-Aminofluorene-d11 is the deuterium labeled 2-Aminofluorene[1]. 2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[2][3][4].
|
-
- HY-158185
-
|
GABA Receptor
|
Others
|
Isocycloseram is an isoxazoline insecticide and acaricide widely recognized as an allosteric modulator of GABA-gated chloride channels. Isocycloseram is active against Lepidopteran, Hemiptera, Coleoptera, Thysanoptera and Diptera pests. Isocycloseram targets the invertebrate Rdl GABA receptor, but the G335M mutation in the third transmembrane domain of the Rdl GABA receptor may mediate resistance .
|
-
- HY-W007980
-
|
Fungal
|
Infection
|
Antifungal agent 98 (compound 2) is an antifungal agent. Antifungal agent 98 (100 μg/mL) shows insecticidal activity against Bipolaris sorokinianum, Fusarium oxysporium f. sp.vasinfectum, Pyricularia oryzae, Alternaria
Brassicae and Alternaria alternata with a death rate of 41.5%, 40.0%, 23.4, 36.8%, and 35.0% .
|
-
- HY-B1161A
-
(+)-Methoprene; (7S)-Methoprene
|
Cannabinoid Receptor
|
Others
|
S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB(1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [ 3H]CP-55940 to the CB1 receptor (IC50: 19.31 μM) .
|
-
- HY-B0815R
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Chlorpyrifos (Standard) is the analytical standard of Chlorpyrifos. This product is intended for research and analytical applications. Chlorpyrifos is a neurotoxic insecticide that belongs to the class of thionite esters. Chlorpyrifos is also a AChE inhibitor that affects neurological function in insects, humans and other animals. Chlorpyrifos interferes with cell replication and differentiation, ultimately altering synaptic transmission in neurons .
|
-
- HY-B0815S
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
|
-
- HY-107577
-
|
HSP
|
Infection
Inflammation/Immunology
Cancer
|
Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research .
|
-
- HY-157016
-
|
Others
|
Others
|
OfChi-h-IN-1 is a potent OfChi-h inhibitor with a Ki value of 0.33 μM. OfChi-h-IN-1 dramatically inhibit the growth and development of Ostrinia nubilalis larvae, and it shows higher insecticidal activity than Hexaflumuron (HY-B1848).?OfChi-h-IN-1 serves as novel candidates for insect growth regulator .
|
-
- HY-120425R
-
|
Others
|
Infection
|
Ethiprole (Standard) is the analytical standard of Ethiprole. This product is intended for research and analytical applications. Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity .
|
-
- HY-W040028R
-
|
Reactive Oxygen Species
|
Infection
|
Cartap (hydrochloride) (Standard) is the analytical standard of Cartap (hydrochloride). This product is intended for research and analytical applications. Cartap hydrochloride, an organonitrogen insecticide, can cause a marked irreversible Ca2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms. Cartap hydrochloride significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells .
|
-
- HY-W127493R
-
|
Biochemical Assay Reagents
|
Infection
|
1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
|
-
- HY-B0900
-
Anise camphor; p-Propenylanisole; Isoestragole
|
Apoptosis
Fungal
Bacterial
MMP
NF-κB
|
Infection
Neurological Disease
Inflammation/Immunology
Cancer
|
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .
|
-
- HY-W024365
-
|
PROTAC Linkers
|
Cancer
|
3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .
|
-
- HY-155331
-
|
Fungal
|
Infection
|
Antifungal agent 77 (Compound 13h) is an antifungal agent. Antifungal agent 77 (500 μg/mL) also shows good insecticidal activity against Mythimna separate, Helicoverpa armigera, Ostrinia nubilalis, and Spodoptera frugiperda with a death rate of 30%, 25%, 40%, and 25%. Antifungal agent 77 shows toxicity in zebrafish embryo with a LC50 of 2.43 μg/mL .
|
-
- HY-W018171R
-
|
Others
|
Others
|
3,5,6-Trichloro-2-pyridinol (Standard) is the analytical standard of 3,5,6-Trichloro-2-pyridinol. This product is intended for research and analytical applications. 3,5,6-Trichloro-2-pyridinol (TCPy) is the main degradation product of the herbicide Triclopyr and the insecticides Chlorpyrifos and Chlorpyrifos-methyl .
|
-
- HY-112820R
-
|
Others
|
Others
|
Chlorantraniliprole (Standard) is the analytical standard of Chlorantraniliprole. This product is intended for research and analytical applications. Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ~300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
|
-
- HY-Y0946R
-
|
Biochemical Assay Reagents
|
Inflammation/Immunology
Cancer
|
Acetamide (Standard) is the analytical standard of Acetamide. This product is intended for research and analytical applications. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies .
|
-
- HY-B0828
-
|
Others
|
Others
|
Triazophos, a non-systemic insecticide and acaricide that acts as an acetylcholinesterase (AChE) inhibitor, covalently and irreversibly binds to the acetylcholine binding site, thus blocking the hydrolysis of acetylcholine and leading to hyperexcitability; it is effective against a variety of soil insects and mites, including aphids, thrips, midges, beetles, Lepidoptera larvae, cutworms, and spider mites in crops such as ornamentals, cotton, rice, maize, soybeans, oil palms, olives, and coffee.
|
-
- HY-B0887
-
NRDC-143
|
Parasite
Mitochondrial Metabolism
Sodium Channel
Na+/K+ ATPase
|
Infection
Neurological Disease
|
Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes) .
|
-
- HY-B0831S
-
|
Oxidative Phosphorylation
Reactive Oxygen Species
|
Metabolic Disease
|
Buprofezin-d6 is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2].
|
-
- HY-117901
-
|
Others
|
Others
|
Sandoricin is a limonoid compound that can be extracted from the seeds of Sandoricum koetjape. Sandoricin exhibits strong antifeedant properties in larvae of Fall Armyworm (Spodoptera frugiperda) and European Corn Borer (Ostrinia nubilalis) fed on artificial diets. Sandoricin induces reduced growth rate and delayed pupation at lower doses, while higher doses cause massive mortality of larvae. Sandoricin is a potential field insecticide .
|
-
- HY-N2534R
-
|
AMPK
Apoptosis
Cytochrome P450
Phosphatase
NF-κB
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Endocrinology
Cancer
|
Karanjin (Standard) is the analytical standard of Karanjin. This product is intended for research and analytical applications. Karanjin is an orally active furanoflavonoid which can be isolated from several Leguminosae. Karanjin exhibits evident anti-diabetic, anti-cancer, anti-inflammatory, antioxidant, anticolitis, anti-ulcer, anti-Alzheimer properties and multiple insect repellent/insecticidal, acaricide properties, suggesting the potential of Karanjin to be applied to relevant research .
|
-
- HY-116870
-
|
Parasite
|
Infection
|
Vamidothion is a polar organophosphorus insecticide and acaricide with biological activity against insects and mites. Vamidothion is degraded by human serum albumin (HSA) and promotes adduct formation with tyrosine residues. The phosphate amino acid adducts formed after the reaction of vamidothion with HSA are detected by liquid chromatography quadrupole-Orbitrap mass spectrometry. The metabolites of vamidothion can be used in forensic toxicology to help determine deaths caused by organophosphorus poisoning .
|
-
- HY-B1837AR
-
beta-Cyfluthrin (Standard)
|
Calcium Channel
|
Neurological Disease
|
β-Cyfluthrin (Standard) is the analytical standard of β-Cyfluthrin. This product is intended for research and analytical applications. β-Cyfluthrin (beta-Cyfluthrin) is a type II synthetic pyrethroid and also an active ingredient of many insecticide products used for pestsin agriculture. β-Cyfluthrin is a neurotoxicant and affects calcium concentration in nervous tissue by inhibiting Ca 2+ ATPase involved in calcium transport .
|
-
- HY-B0816R
-
|
Others
|
Others
|
Etofenprox (Standard) is the analytical standard of Etofenprox. This product is intended for research and analytical applications. Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
|
-
- HY-163980
-
|
Cholinesterase (ChE)
nAChR
|
Others
|
AChE-IN-73 (compound 6) is an insecticide with higher toxicity than HY-B0815. The LC50 for C. pipiens is 78.0 mg/L. AChE-IN-73 has high affinity for acetylcholinesterase (AChE) and nicotinic acetylcholine receptors (nAChR), with binding energies of -8.11 kcal/mol and -6.27 kcal/mol, respectively. AChE-IN-73 is a potentially potent mosquito inhibitor .
|
-
- HY-N6690
-
|
Bcl-2 Family
Caspase
Apoptosis
|
Infection
Cancer
|
Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family-dependent mitochondrial pathway in human nonsmall cell lung cancer cells . Destruxin B significantly activates caspase-3 and reduces tumor cell proliferation through caspase-mediated apoptosis, not only in vitro but also in vivo .
|
-
- HY-114936
-
AR-054
|
Bacterial
ADC Cytotoxin
Antibiotic
Mitochondrial Metabolism
|
Infection
Neurological Disease
Cancer
|
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .
|
-
- HY-N6739
-
|
Bacterial
Apoptosis
Fungal
PI3K
Akt
TNF Receptor
Interleukin Related
|
Infection
Cancer
|
Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .
|
-
- HY-117386
-
|
Parasite
|
Others
|
Methoxyfenozide, a diacylhydrazine insecticide, selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s=0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively).
|
-
- HY-B2041
-
|
Others
|
Infection
|
Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development .
|
-
- HY-B0837
-
MK-244
|
Parasite
GABA Receptor
Reactive Oxygen Species
Apoptosis
|
Infection
Neurological Disease
|
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .
|
-
- HY-B0822
-
|
GABA Receptor
Cytochrome P450
Apoptosis
|
Neurological Disease
|
Fipronil is a broad-spectrum insecticide effective against Lepidoptera species as well as thrips, locusts, ants, cockroaches, fleas and ticks. Fipronil selectively inhibits GABA receptor with IC50s of 30 nM and 1600 nM for cockroach and rat GABA receptors, respectively. Glutamate-gated chloride channels (GluCls), which are present in cockroaches but not in mammals, are sensitive to the blocking effect of Fipronil. Fipronil also induces apoptosis in HepG2 cells and promotes the expression of CYP1A1 and CYP3A4 mRNA in human hepatocytes .
|
-
- HY-15866
-
|
Others
|
Cancer
|
FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research .
|
-
- HY-117386S
-
|
Isotope-Labeled Compounds
|
Others
|
Methoxyfenozide-d9 is the deuterium labeled Methoxyfenozide[1]. Methoxyfenozide, a diacylhydrazine insecticide, selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s=0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively)[2].
|
-
- HY-117386R
-
|
Parasite
|
Others
|
Methoxyfenozide (Standard) is the analytical standard of Methoxyfenozide. This product is intended for research and analytical applications. Methoxyfenozide, a diacylhydrazine insecticide, selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s=0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively).
|
-
- HY-15311
-
Abamectin; Avermectin B1a-Avermectin B1b mixt.
|
Parasite
Autophagy
Apoptosis
Reactive Oxygen Species
Antibiotic
|
Infection
Inflammation/Immunology
|
Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .
|
-
- HY-118607
-
|
Potassium Channel
Parasite
|
Infection
|
VU041 is a first submicromolar-affinity inhibitor of Anopheles (An.) gambiae and Aedes (Ae.) aegypti inward rectifier potassium 1 (Kir1) channels with IC50 values of 2.5?μM and 1.7?μM, respectively. VU041 inhibits appreciably is mammalian Kir2.1 (IC50 of 12.7?μM), and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. VU041 also induces impaired Malpighian tubule function .
|
-
- HY-15311R
-
|
Parasite
Autophagy
Apoptosis
Reactive Oxygen Species
Antibiotic
|
Infection
Inflammation/Immunology
|
Avermectin B1 (Standard) is the analytical standard of Avermectin B1. This product is intended for research and analytical applications. Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .
|
-
- HY-W010176
-
3,7-Dimethyloctan-1-ol
|
Biochemical Assay Reagents
|
Others
|
3,7-Dimethyloctan-1-ol, 3,7-Dimethyloctan-1-ol is commonly used as a flavor and fragrance ingredient due to its pleasant aroma, it can also be used as a solvent, and in the synthesis of various organic compounds (including pharmaceuticals and agrochemicals), in addition, due to its high energy content and low volatility, 3,7-Dimethyloctan-1-ol has been investigated for its potential use as a biofuel, due to its toxicity to some pests, it has also been studied as a potential repellent and insecticide,
|
-
- HY-B0822R
-
|
GABA Receptor
Cytochrome P450
Apoptosis
|
Neurological Disease
|
Fipronil (Standard) is the analytical standard of Fipronil. This product is intended for research and analytical applications. Fipronil is a broad-spectrum insecticide effective against Lepidoptera species as well as thrips, locusts, ants, cockroaches, fleas and ticks. Fipronil selectively inhibits GABA receptor with IC50s of 30 nM and 1600 nM for cockroach and rat GABA receptors, respectively. Glutamate-gated chloride channels (GluCls), which are present in cockroaches but not in mammals, are sensitive to the blocking effect of Fipronil. Fipronil also induces apoptosis in HepG2 cells and promotes the expression of CYP1A1 and CYP3A4 mRNA in human hepatocytes .
|
-
- HY-N0928
-
|
Apoptosis
|
Inflammation/Immunology
Cancer
|
Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity . Mimosine is a known chelator of Fe(III) . Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells . Anti-cancer, antiinflammation.
|
-
- HY-B0822S1
-
|
GABA Receptor
Cytochrome P450
|
Inflammation/Immunology
|
Fipronil- 13C6 is the 13C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
|
-
- HY-N3980
-
Champacol; Guaiac alcohol
|
Autophagy
RAD51
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-N3980R
-
|
Autophagy
RAD51
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-W027592
-
|
Biochemical Assay Reagents
|
Others
|
1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.
|
-
- HY-W050154R
-
|
Parasite
Tyrosinase
NF-κB
CDK
|
Infection
Inflammation/Immunology
Cancer
|
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .
|
-
- HY-117146
-
(S)-DPX-JW062
|
Parasite
|
Infection
|
Indoxacarb ((S)-DPX-JW062) is an oxathiazole insecticide with activity against a wide range of insect pests. Indoxacarb is used in forest pest management to control insect pests, and its toxicity has significant effects on adult individuals of the predatory stink bug Podisus distinctus. Indoxacarb showed high toxicity to P. distinctus at a lethal concentration (LC50 = 2.62 g L-1). Indoxacarb treatment significantly reduced the survival rate of P. distinctus, with the survival rate of individuals exposed to 2.62 g L-1 decreasing to 40.7%. Indoxacarb also reduced the respiration rate of P. distinctus from 18.45 to 14.41 μL CO2 h-1, and inhibited its food intake. P. distinctus showed hyperexcitatory responses after Indoxacarb treatment .
|
-
- HY-Y0148
-
NSC 15139; 10-HDAA
|
Parasite
Autophagy
NF-κB
Interleukin Related
NO Synthase
MDM-2/p53
TNF Receptor
RANKL/RANK
Caspase
|
Infection
Neurological Disease
Inflammation/Immunology
|
10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid, which can be isolated from royal jelly. 10-Hydroxydecanoic acid exhibits various biological activities, including anti-inflammatory, insecticidal, anti-malarial, and anti-Leishmania properties, as well as enhancing antigen-specific immune responses. The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF-κB and the translation of interferon regulatory factor 1 (IRF-1), which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells. Additionally, 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway. Finally, 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells .
|
-
- HY-138074
-
5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime
|
Parasite
|
Infection
|
Milbemycin A4 oxime is a derivative of milbemycin A4 (Item No. 17155) and a component of Milbemycin Oxime (HY-B0778), compounds that both have insecticidal and nematocidal activity. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae of the heartworm D. immitis in naturally infested dogs. It inhibits the growth of clinical isolates of C. glabrata with MIC80 values ranging from 16 to greater than 32 μg/mL.1 Milbemycin A4 oxime (2.5 μg/mL) blocks efflux of Fluconazole (HY-B0101) from a clinical isolate of C. glabrata, but not from a strain lacking the efflux pumps CgCDR1 and PDH1, and reduces the MICs of fluconazole and 4-nitroquinoline 1-oxide in wild-type C. glabrata. It enhances adriamycin-induced inhibition of cell growth, as well as increases the intracellular accumulation of adriamycin and the P-glycoprotein substrate Rhodamine 123 (HY-D0816), in adriamycin-resistant, but not -sensitive, MCF-7 breast cancer cells in a concentration-dependent manner.
|
-
- HY-W027592R
-
|
Biochemical Assay Reagents
|
Others
|
1H-1,2,4-Triazol-3-amine (Standard) is the analytical standard of 1H-1,2,4-Triazol-3-amine. This product is intended for research and analytical applications. 1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.
|
-
-
-
HY-L183
-
|
286 compounds
|
Pesticide is a single substance or mixture that can be used to prevent, mitigate, iminate pests or as a plant conditioner, defoliant or desiccant. In recent years, scientists have proposed the concept of "Molecules to Ecosystems", bringing the concept of molecular biology to understand the impact of pesticides, degradation and relationship with the environment or organisms. MCE integrates effective compounds approved as pesticides by agencies such as the Environmental Protection Agency (EPA) and some insecticidal compounds with potential for agricultural applications.
MCE can provide a library of 286 pesticide compounds that are tool compounds for relevant research.
|
Cat. No. |
Product Name |
Type |
-
- HY-W059342
-
YI-5301
|
Biochemical Assay Reagents
|
Etoxazole (YI-5301) is an organofluorine insecticide widely used in agriculture. Etoxazole affects the nymphs, eggs, and larvae of spider mites by inhibiting chitin biosynthesis .
|
-
- HY-Y1887
-
|
Co-solvents
|
Cottonseed oil is a cooking oil extracted from the seeds of cotton plants and has been generally considered the most insecticidal of vegetable oils.
|
-
- HY-W115752
-
Diamine sulfate (99%)
|
Cell Assay Reagents
|
Hydrazine sulfate (99%) (Diamine sulfate (99%)) is used as an insecticide, sterilant, and plant growth inhibitor in agriculture. Hydrazine sulfate (99%) is a biomaterial or organic compound that can be used in life science research .
|
-
- HY-W127493
-
Ceryl Alcohol
|
Cell Assay Reagents
|
1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
|
-
- HY-W027592
-
|
Cell Assay Reagents
|
1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.
|
-
- HY-W059342R
-
|
Biochemical Assay Reagents
|
Etoxazole (Standard) is the analytical standard of Etoxazole. This product is intended for research and analytical applications. Etoxazole (YI-5301) is an organofluorine insecticide widely used in agriculture. Etoxazole affects the nymphs, eggs, and larvae of spider mites by inhibiting chitin biosynthesis .
|
-
- HY-W127474
-
|
Drug Delivery
|
Ethyl pentadecanoate is an organic compound that is commonly used as a flavoring and food additive, and can also be used in industrial manufacturing, such as the production of lubricants and surfactants. In addition, Ethyl pentadecanoate has biological activities such as antibacterial, insecticidal and antiseptic.
|
-
- HY-W127493R
-
|
Cell Assay Reagents
|
1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
|
-
- HY-W010176
-
3,7-Dimethyloctan-1-ol
|
Biochemical Assay Reagents
|
3,7-Dimethyloctan-1-ol, 3,7-Dimethyloctan-1-ol is commonly used as a flavor and fragrance ingredient due to its pleasant aroma, it can also be used as a solvent, and in the synthesis of various organic compounds (including pharmaceuticals and agrochemicals), in addition, due to its high energy content and low volatility, 3,7-Dimethyloctan-1-ol has been investigated for its potential use as a biofuel, due to its toxicity to some pests, it has also been studied as a potential repellent and insecticide,
|
-
- HY-W027592R
-
|
Cell Assay Reagents
|
1H-1,2,4-Triazol-3-amine (Standard) is the analytical standard of 1H-1,2,4-Triazol-3-amine. This product is intended for research and analytical applications. 1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-N6693
-
NSC 122023
|
Apoptosis
Antibiotic
Autophagy
Fungal
|
Infection
Others
Cancer
|
Valinomycin is a potassium-specific ionophore, the valinomycin-K + complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K + gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research .
|
-
- HY-N6689
-
|
Antibiotic
|
Infection
Cancer
|
Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities .
|
-
- HY-P10390
-
|
Parasite
|
Infection
|
Insecticidal agent 11 (compound Q6) is a potent insect growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .
|
-
- HY-125040
-
-
- HY-B1603S
-
|
Peptides
|
Others
|
Chlorophenothane-d8 is the deuterium labeled Chlorophenothane. Chlorophenothane has stomach poisoning and contact killing effects. Chlorophenothane has been widely used as an insecticide .
|
-
- HY-P3100
-
|
Parasite
|
Infection
|
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-101417
-
-
- HY-N3507
-
-
- HY-N3076
-
-
- HY-N6689
-
-
- HY-N1304
-
-
- HY-126872
-
-
- HY-114502
-
-
- HY-N0263
-
-
- HY-114720
-
-
- HY-N10682
-
-
- HY-W009165
-
-
- HY-N1418A
-
-
- HY-N11761
-
-
- HY-N7144A
-
-
- HY-114373
-
-
- HY-N12210
-
-
- HY-126744
-
-
- HY-N12131
-
-
- HY-126383
-
-
- HY-N7144AR
-
-
- HY-Y0946
-
-
- HY-N2534
-
-
- HY-N1487
-
-
- HY-107577
-
-
- HY-B0900
-
Anise camphor; p-Propenylanisole; Isoestragole
|
Structural Classification
Classification of Application Fields
Source classification
Plants
Microorganisms
Simple Phenylpropanols
Leguminosae
Phenylpropanoids
Umbelliferae
Vernonia Schreb.
Glycyrrhiza uralensis Fisch.
Disease Research Fields
Cancer
|
Apoptosis
Fungal
Bacterial
MMP
NF-κB
|
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .
|
-
- HY-W024365
-
-
- HY-Y0946R
-
-
- HY-117901
-
-
- HY-N2534R
-
-
- HY-N6690
-
-
- HY-114936
-
-
- HY-N6739
-
-
- HY-15311
-
-
- HY-15311R
-
-
- HY-N0928
-
-
- HY-N3980
-
Champacol; Guaiac alcohol
|
Infection
Structural Classification
Natural Products
Classification of Application Fields
Source classification
Distemonanthus benthamianus Baill.
Plants
Compositae
Disease Research Fields
|
Autophagy
RAD51
|
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-N3980R
-
|
Structural Classification
Natural Products
Source classification
Distemonanthus benthamianus Baill.
Plants
Compositae
|
Autophagy
RAD51
|
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-W050154R
-
|
Structural Classification
Human Gut Microbiota Metabolites
Microorganisms
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
|
Parasite
Tyrosinase
NF-κB
CDK
|
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .
|
-
- HY-Y0148
-
NSC 15139; 10-HDAA
|
Structural Classification
Animals
Classification of Application Fields
Ketones, Aldehydes, Acids
Source classification
Inflammation/Immunology
Disease Research Fields
|
Parasite
Autophagy
NF-κB
Interleukin Related
NO Synthase
MDM-2/p53
TNF Receptor
RANKL/RANK
Caspase
|
10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid, which can be isolated from royal jelly. 10-Hydroxydecanoic acid exhibits various biological activities, including anti-inflammatory, insecticidal, anti-malarial, and anti-Leishmania properties, as well as enhancing antigen-specific immune responses. The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF-κB and the translation of interferon regulatory factor 1 (IRF-1), which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells. Additionally, 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway. Finally, 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-133167S
-
|
Clothianidin-d3 is the deuterium labeled Clothianidin.Clothianidin-d3 is a neonicotinoid insecticide. Clothianidin-d3 shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin-d3 has various application methods and high safety for crops .
|
-
-
- HY-B0833S1
-
|
Thiamethoxam-d3 is the deuterium labeled Thiamethoxam[1]. Thiamethoxam is a broad spectrum neonicotinoid insecticide[2][3].
|
-
-
- HY-132457S
-
|
Fenthion-d6 is a deuterium labeled Fenthion. Fenthion is an organophosphorus insecticide[1][2].
|
-
-
- HY-B0830S
-
|
Isoprocarb-d3 is deuterium labeled Isoprocarb. Isoprocarb is carbamate insecticide that widely used to control rice paddy lice and leafhopper. Isoprocarb is also an AChE inhibitor[1].
|
-
-
- HY-B0823S
-
|
Acetamiprid-d3 is the deuterium labeled Acetamiprid. Acetamiprid is a neonicotinoid insecticide. Acetamiprid is a nAChR agonist[1].
|
-
-
- HY-114899S
-
|
Azamethiphos-d6 is deuterated labeled Azamethiphos. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .
|
-
-
- HY-132409S
-
|
Monocrotophos-d6 is the deuterium labeled Monocrotophos. Monocrotophos. Monocrotophos is an organophosphate insecticide with broad application in crops. Monocrotophos inhibits the activity of the acetylcholine esterase (AChE) enzyme and affects the neurotransmission between neurons[1].
|
-
-
- HY-B0835S
-
|
Fenobucarb-d3 is the deuterium labeled Fenobucarb. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis[1].
|
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- HY-B1315S1
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Carbaryl-d7 is the deuterium labeled Carbaryl[1]. Carbaryl is used chiefly as an insecticide[2].
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- HY-I1111S1
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Fmoc-L-Val-OH-1- 13C is a 13C-labeled Carbaryl. Carbaryl is used chiefly as an insecticide[1].
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- HY-W654238
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Imidaclothiz-d4 is deuterium labeled Imidaclothiz. Imidaclothiz is a kind of neonicotinoid insecticides. Imidaclothiz has excellent insecticidal effect. Imidaclothiz can be used for the research of sucking and biting insects .
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- HY-B1973S
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Diflubenzuron-d4 is the deuterium labeled Diflubenzuron[1]. Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities[2][3].
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- HY-12779S
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Cyantraniliprole-d3 is the deuterium labeled Cyantraniliprole, which is an insecticide of the ryanoid class.
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- HY-12643S
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Eprinomectin-d3 (MK-397-d3) is the deuterium-labeled Eprinomectin (HY-12643). Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity .
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- HY-B1885S
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Fenitrothion-d6 is the deuterium labeled Fenitrothion[1]. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols[2][3].
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- HY-116448S
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Metaflumizone-d4 is deuterium labeled Metaflumizone. Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker[1].
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- HY-123178S
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Fenpropathrin-d5 is the deuterium labeled Fenpropathrin. Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively[1].
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- HY-B0841S
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Acephate-d3 is the deuterium labeled Acephate. Acephate is an anticholinesterase insecticide that produces cholinotoxicity. Acephate displays weak inhibition of rat AChE but potently inhibits cockroach AChE.
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- HY-101417S1
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Diethyl phosphate-d10-1 is the deuterium labeled Diethyl phosphate[1]. Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos.
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- HY-B0887S1
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Permethrin-d9 is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
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- HY-Y0946S
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Acetamide- 15N is the 15N-labeled Acetamide. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[1][2].
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- HY-B1971S
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Deltamethrin-d5 is the deuterium labeled Deltamethrin. Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis[1][2].
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- HY-Y0055S
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Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].
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- HY-Y0946S2
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Acetamide-d5 is the deuterium labeled Acetamide[1]. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[2][3].
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- HY-B0827S
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Dinotefuran-d3 is the deuterium labeled Dinotefuran[1]. Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors[2].
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- HY-W778140
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Diethyl phosphate- 13C4 (sodium) is the 13C labeled isotope of Diethyl phosphate- 13C4 (sodium)(HY-101417).Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos .
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- HY-B1331S
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Cyromazine-d4 is the deuterium labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
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- HY-B1111S1
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Amitraz-d3 is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.
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- HY-115584S
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Lufenuron- 13C6 is a 13C-labeled Lufenuron. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods[1][2].
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- HY-B2006S
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Fenvalerate-d5 is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1].
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- HY-B1331S1
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Cyromazine- 13C3 is the 13C3 labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
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- HY-B1161S
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Methoprene-d7 is the deuterium labeled Methoprene[1]. Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist[2][3].
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- HY-16973S
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Fluralaner- 13C2, 15N,d3 is the deuterium, 13C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
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- HY-B0887S
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Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].
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- HY-W753602
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Acetamiprid-N-desmethyl- 13C,d3 is the 13C and deuterium labeled isotope of Acetamiprid-N-desmethyl( 13C,d3)(HY-B0823).Acetamiprid is a nAChR agonist that has been implicated in neuromuscular and reproductive disorders.
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- HY-B1111S
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Amitraz-d6 (BTS-27419-d6) is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.
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- HY-I1111S2
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Fmoc-L-Val-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pirimicarb. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an
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- HY-B1946S
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Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects[1].
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- HY-B1953S
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Thiacloprid-d4 is the deuterium labeled Thiacloprid[1]. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].
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- HY-B1881S
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Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains[1][2][3].
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- HY-W016433S
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2-Aminofluorene- 13C is the 13C labeled 2-Aminofluorene[1]. 2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[2][3][4].
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- HY-W016433S1
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2-Aminofluorene-d11 is the deuterium labeled 2-Aminofluorene[1]. 2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[2][3][4].
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- HY-B0815S
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Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
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- HY-B0831S
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Buprofezin-d6 is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2].
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- HY-117386S
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Methoxyfenozide-d9 is the deuterium labeled Methoxyfenozide[1]. Methoxyfenozide, a diacylhydrazine insecticide, selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s=0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively)[2].
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- HY-B0822S1
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Fipronil- 13C6 is the 13C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
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Cat. No. |
Product Name |
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Classification |
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- HY-136396
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Alkynes
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Chlorempenthrin is a synthetic pyrethroid insecticide . Chlorempenthrin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No. |
Product Name |
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Classification |
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- HY-Y1887
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Solvents
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Cottonseed oil is a cooking oil extracted from the seeds of cotton plants and has been generally considered the most insecticidal of vegetable oils.
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