Search Result
Results for "
Fmoc
" in MedChemExpress (MCE) Product Catalog:
18
Biochemical Assay Reagents
76
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W007052
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- HY-78933
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Microtubule/Tubulin
ADC Cytotoxin
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Cancer
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Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC .
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- HY-W048682
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Amino Acid Derivatives
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Others
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Fmoc-1-methyl-L-histidine is a Fmoc protected amino acid and can be used as an intermediate for peptide synthesis .
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- HY-W052227
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- HY-159135
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- HY-148339
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Drug-Linker Conjugates for ADC
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Others
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Fmoc-VAP-MMAE is a agent-linker conjugates for ADC. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE (HY-15162), with a protective Fmoc group .
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- HY-W013152
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- HY-W088805
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Fmoc-3-carboxypiperidine
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Amino Acid Derivatives
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Others
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Fmoc-NIP-OH (Fmoc-3-carboxypiperidine) is a Fmoc-protected amino acid derivative commonly used in peptide synthesis .
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- HY-P2392
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- HY-W013123
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Amino Acid Derivatives
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Others
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Fmoc-D-Phe(4-CF3)-OH is Phenylalanine derivative. Fmoc-D-Phe(4-CF3)-OH can be used for the research of peptide inhibitors of protein-protein interactions .
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- HY-41189
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ADC Linker
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Cancer
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Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers .
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- HY-W010712
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Amino Acid Derivatives
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Others
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Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .
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- HY-Y1636
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Amino Acid Derivatives
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Others
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Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
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- HY-Y1169
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4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
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Amino Acid Derivatives
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Others
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Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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- HY-W072147
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Fmoc-L-Ser-OMe
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Amino Acid Derivatives
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Others
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Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .
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- HY-W008386
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- HY-W013083
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- HY-W013750
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- HY-W008064
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Fmoc-L-Citrulline
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Amino Acid Derivatives
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Cancer
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Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif .
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- HY-103664A
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Others
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Cancer
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Fmoc-1,6-diaminohexane hydrochloride is the hydrochloride form of Fmoc-1,6-diaminohexane (HY-103664). Fmoc-1,6-diaminohexane hydrochloride conjugates with monoclonal antibody, and exhibits anticancer activity against p21-deficient cancer .
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- HY-W004101
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- HY-W022255
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D-Fmoc-glutamic acid
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Amino Acid Derivatives
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Others
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Fmoc-D-Glu-OH (D-Fmoc-glutamic acid) is a derivative of glutamate, can be used to prepare supramolecular hydrogels .
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- HY-W048722
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Fmoc-D-2-Thienylalanine
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Amino Acid Derivatives
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Others
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Fmoc-D-Thi-OH (Fmoc-D-2-Thienylalanine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize AS-Z-P with thrombin inhibitory activity .
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- HY-W142161
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Fmoc-MeHis(Trt)-OH
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Amino Acid Derivatives
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Others
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Fmoc-N-Me-His(Trt)-OH (Fmoc-MeHis(Trt)-OH) is a is an amino acid derivative containing amino and carboxyl groups. Fmoc-N-Me-His(Trt)-OH for the synthesis of Fmoc-MeHis (Trt) -Leu-OH .
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- HY-I1111
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- HY-W048674
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Fmoc-O-acetyl-L-serine
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Amino Acid Derivatives
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Infection
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Fmoc-Ser(Ac)-OH (Fmoc-O-acetyl-L-serine) is a Serine derivative. Fmoc-Ser(Ac)-OH can be used for the preparation of broad-spectrum coronavirus membrane fusion inhibitor .
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- HY-101064S3
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PPAR
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Metabolic Disease
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Fmoc-leucine-d10 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].
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- HY-W048209
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Amino Acid Derivatives
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Others
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Fmoc-Lys(Palmitoyl)-OH is a Fmoc-amino acid with long alkyl chains. Fmoc-Lys(Palmitoyl)-OH can be used for peptide synthesis .
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- HY-156848
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Drug-Linker Conjugates for ADC
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Cancer
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Fmoc-GGFG-DXd is a drug-linker conjugate for ADC. Fmoc-GGFG-DXd contains a ADC linker Fmoc-GGFG and a DNA topoisomerase I inhibitor DXd (HY-13631D) .
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- HY-19821
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- HY-W010895
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- HY-W013162
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- HY-W010893
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- HY-W011020
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- HY-W008963
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Nα-Fmoc-D-tryptophan; Fmoc-D-Trp-OH
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Biochemical Assay Reagents
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Others
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Fmoc-D-Trp-OH (Nα-Fmoc-D-tryptophan) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W048718
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Fmoc-D-α-t-butylglycine
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Amino Acid Derivatives
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Others
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Fmoc-D-Tle-OH (Fmoc-D-α-t-butylglycine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize chelating agents that can form a single stereoisomer-enriched form after coordination with metal centers .
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- HY-W338516
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Amino Acid Derivatives
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Others
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Fmoc-L-Homoarginine hydrochloride is a derivative of amino acid with protecting groups. Fmoc-L-Homoarginine hydrochloride can be used for synthesis of homoarginine containing peptide .
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- HY-79255
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ADC Cytotoxin
Microtubule/Tubulin
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Cancer
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Fmoc-MMAF-OMe is an anticancer agent and tubulin polymerization inhibitor with an Fmoc protecting group. The active ingredient of Fmoc-MMAF-OMe, MMAF (HY-15579), is the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs) .
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- HY-W097054
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Amino Acid Derivatives
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Others
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Fmoc-L-cysteic acid is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize triarylsulfonium compounds for radiolabeling of peptides .
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- HY-22295
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Biochemical Assay Reagents
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Others
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Fmoc-4-aminobutanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-Y1250S5
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- HY-W009118
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Amino Acid Derivatives
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Others
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Fmoc-5-Ava-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize fatty acid-based dimeric peptides with PSD-95 inhibitory activity .
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- HY-79131S5
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- HY-W022223
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- HY-19821S
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- HY-W010756
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- HY-W009034
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- HY-W011021
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- HY-W007713
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Fmoc-NH-PEG2-CH2COOH
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ADC Linker
PROTAC Linkers
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Cancer
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Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-8-amino-3,6-dioxaoctanoic acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W009204S5
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Isotope-Labeled Compounds
PPAR
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Metabolic Disease
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Fmoc-Ala-OH- 13C3 is a 13C-labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-ind
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- HY-79131S4
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- HY-W007720S
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- HY-W007720S1
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- HY-W008371S2
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- HY-W009204S8
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- HY-W013780S3
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- HY-W002327
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Biochemical Assay Reagents
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Others
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Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .
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- HY-W041988
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Bacterial
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Infection
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Fmoc-Glu-OMe, a glutamic acid derivative, shows antibacterial activity and gelation property in AgNO3 solution. Fmoc-Glu-OMe is a mouldable wound healing biomaterial .
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- HY-101064
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N-Fmoc-leucine; NPC 15199; NSC 334290
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PPAR
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Metabolic Disease
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Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity .
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- HY-78921
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ADC Linker
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Cancer
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Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W013154
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Amino Acid Derivatives
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Others
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Fmoc-Tic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as the biotinylated derivative of the opioid receptor antagonist TIPP .
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- HY-19811
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- HY-W052227S
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- HY-I1111S
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- HY-W142064
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Antibiotic
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Others
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Fmoc-L-photo-proline is a photo-crosslinking amino acid which can be incorporated into synthetic peptides using solid-phase Fmoc chemistry. Fmoc-L-photo-proline can synthesis of cyclic peptidomimetic antibiotic and be used for preparation of diverse peptide-based photoaffinity probes research .
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- HY-W048825
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Amino Acid Derivatives
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Others
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Fmoc-Ala-Ala-OH (3) is a self-assemble fluorenylmethoxycarbonyl-dipeptide, which is a smaller amphiphilic building blocks consists dipeptides linked to fluore nylmethoxycarbonyl (Fmoc). Fmoc-Ala-Ala-OH can be used as scaffold materials in 3D cell culture .
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- HY-W009204S
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- HY-W008371S
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- HY-Y1250S
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- HY-79131S2
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- HY-W009204S6
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- HY-W008688
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- HY-W011084
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- HY-19318G
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ADC Linker
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Cancer
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Fmoc-Val-Cit-PAB GMP is a GMP grade Fmoc-Val-Cit-PAB (HY-19318). Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker.
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- HY-W008235
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- HY-W008558
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- HY-Y1250S3
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- HY-148462
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ADC Linker
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Cancer
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Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-46398
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PROTAC Linkers
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Cancer
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Fmoc-Val-Phe-Boc is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Val-Phe-Boc can be used in the synthesis of the Deruxtecan .
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- HY-W010975
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ADC Linker
PROTAC Linkers
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Cancer
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Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W013190
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- HY-W009003
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- HY-W009005
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- HY-W009085
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- HY-W009088
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- HY-W010793
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- HY-W007020
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- HY-W007720
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- HY-W008176
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- HY-W008475
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- HY-W008696
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- HY-W041982
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- HY-W010959
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- HY-W011000
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- HY-W011081
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- HY-W011135
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- HY-W008360
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- HY-W041991
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- HY-W141948
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- HY-79648
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- HY-79131
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- HY-W019028
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- HY-22297
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- HY-W009204
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- HY-W009151
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- HY-W013780
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- HY-W007941S1
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- HY-W010758
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- HY-W010922
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Amino Acid Derivatives
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Others
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Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists .
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- HY-W008876
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Amino Acid Derivatives
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Others
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Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II .
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- HY-101064S1
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Isotope-Labeled Compounds
PPAR
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Metabolic Disease
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Fmoc-leucine- 13C6, 15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity
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- HY-W007798S1
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Isotope-Labeled Compounds
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Others
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Fmoc-Cys(Trt)-OH-d2 is the deuterium labeled Fmoc-Cys(Trt)-OH. Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative[1].
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- HY-151637
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Amino Acid Derivatives
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Others
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Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures . Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-Y1636S1
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Isotope-Labeled Compounds
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Others
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Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].
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- HY-78921AG
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ADC Linker
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Cancer
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Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W041989
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Amino Acid Derivatives
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Others
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Fmoc-Oic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg 10]HOE 140, which has bradykinin B1 antagonist activity .
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- HY-134517
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Amino Acid Derivatives
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Others
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Fmoc-HoCys(ACM)-OH, a homolog of cysteine, is synthesized from L-methionine. Fmoc-HoCys(ACM)-OH also can be used for the synthesis of solid phase peptide .
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- HY-W048671
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Amino Acid Derivatives
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Others
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Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted research .
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- HY-W008205
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Fmoc-L-Hydroxyproline
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Biochemical Assay Reagents
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Others
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Fmoc-Hyp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W008072S
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- HY-W011026S
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- HY-W011026S1
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- HY-W011002
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- HY-W010880
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- HY-W016032
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- HY-157248
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- HY-W010712S1
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Isotope-Labeled Compounds
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Others
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Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
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- HY-153151
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Drug Intermediate
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Cancer
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Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .
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- HY-103664
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- HY-W048688
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Amino Acid Derivatives
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Others
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Fmoc-Trp(Me)-OH is synthesized by N-(9-Fluorenylmethoxycarbonyloxy)succinimide (Fmoc-ONSu) and 1-Methyl-Ltrypthophan and can be used for protein or peptide synthesis .
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- HY-W101305
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Amino Acid Derivatives
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Others
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Fmoc-Pen(Acm)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize chemically modified cyclic peptides containing cell adhesion recognition (CAR) sequences .
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- HY-W019032
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Amino Acid Derivatives
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Others
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Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .
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- HY-164166
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Biochemical Assay Reagents
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Others
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Fmoc-Sar-Sar-Sar-OH is a small molecule polypeptide composed of four sarcosine residues, in which the N-terminus of the peptide chain is protected by Fmoc. Fmoc-Sar-Sar-Sar-OH can be used for peptide synthesis or synthesis of drug-peptide ligand conjugates .
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- HY-W004864
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Amino Acid Derivatives
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Others
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Fmoc-(S)-2-(4-pentenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active secretin analogs .
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- HY-W009204S3
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- HY-W009204S2
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- HY-79131S
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- HY-Y0134S
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- HY-W011210
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Amino Acid Derivatives
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Others
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Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W008371
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- HY-128929
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ADC Linker
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Cancer
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Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC) .
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- HY-W048739
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Amino Acid Derivatives
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Others
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Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .
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- HY-W141987
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- HY-W142030
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- HY-W747366
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- HY-131833A
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-D-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OH is the D-isomer of Fmoc-Gly-Gly-Phe-OH (HY-131833).
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- HY-131833G
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-112516
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Others
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Others
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Fmoc-Lys(amino aldehyde)-Boc is a lysine derivative, and is very sensitive to acid and heat. Fmoc-Lys(amino aldehyde)-Boc and can be used in solid phase synthesis .
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- HY-79128
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- HY-44234A
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ADC Linker
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Cancer
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Fmoc-Gly-Gly-D-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OtBu is the R-isomer of Fmoc-Gly-Gly-Phe-OtBu (HY-44234) .
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- HY-W041983
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- HY-W011342
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- HY-W010839
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- HY-W041984
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- HY-140945
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PROTAC Linkers
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Cancer
|
Fmoc-Lys (biotin-PEG12)-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W008024
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release .
|
-
- HY-W009006
-
-
- HY-W009124
-
-
- HY-134852
-
-
- HY-137950
-
-
- HY-W097163
-
-
- HY-22296
-
-
- HY-W010721
-
-
- HY-W010782
-
-
- HY-W141946
-
-
- HY-W005815
-
-
- HY-W141985
-
-
- HY-W025807
-
-
- HY-W007108
-
-
- HY-W007706
-
-
- HY-W007941
-
-
- HY-W008016
-
-
- HY-W008072
-
-
- HY-W008869
-
-
- HY-W008872
-
-
- HY-W008958
-
-
- HY-W008986
-
-
- HY-W008926
-
-
- HY-W008273
-
-
- HY-W008256
-
-
- HY-W008075
-
-
- HY-W010962
-
-
- HY-W010964
-
-
- HY-W010965
-
-
- HY-W011026
-
-
- HY-W011089
-
-
- HY-W013118
-
-
- HY-W013143
-
-
- HY-W013145
-
-
- HY-W013185
-
-
- HY-W011126
-
-
- HY-W013659
-
-
- HY-W010976
-
-
- HY-W041990
-
-
- HY-W040024
-
-
- HY-W007942
-
-
- HY-W002436
-
-
- HY-W010943
-
-
- HY-W010862
-
-
- HY-W010830
-
-
- HY-W010794
-
-
- HY-W010734
-
-
- HY-W009119
-
-
- HY-W007798
-
-
- HY-W142115
-
-
- HY-W008021
-
-
- HY-159136
-
-
- HY-W010729
-
-
- HY-P4198
-
-
- HY-79125
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-Hyp(Bom)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Hyp(Bom)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<
|
-
- HY-W111226
-
|
Amyloid-β
Amino Acid Derivatives
|
Cardiovascular Disease
|
Fmoc-His(3-Me)OH derives Histidine-associating compounds with biological activity. Fmoc-His(3-Me)OH, with Fmoc-citrulline-OH, Fmoc-His(1-Me)-OH together, forms tri-peptides and shows vasodilating effect with EC50s of 2.7-4.7 mM in 1.0 mM Phenylephrine (PE)-contracted aorta rings. Fmoc-His(3-Me)OH (resin) also makes Methyl-His-Gly-Lys (His(3-Me)-Gly-Lys), thus acts as an [Ca 2+]i inhibitor. Fmoc-His(3-Me)OH methylates NAHIS02, making it unable to block the Alzheimer's Aβ channel .
|
-
- HY-W013153
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Tic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg 10]HOE 140, which has bradykinin B1 antagonist activity .
|
-
- HY-I1111S3
-
-
- HY-130477
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151695
-
N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine
|
ADC Linker
|
Others
|
Fmoc-L-Lys(Pryoc)-OH (N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine) is a click chemistry reagent containing an azide group .
|
-
- HY-151640
-
|
ADC Linker
|
Others
|
Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-101064S2
-
N-Fmoc-leucine-d3; NPC 15199-d3; NSC 334290-d3
|
PPAR
|
Metabolic Disease
|
Fmoc-leucine-d3 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].
|
-
- HY-79128S
-
-
- HY-W048697
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand .
|
-
- HY-W011277
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-azetidine-3-carboxylic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-151780
-
|
ADC Linker
|
Others
|
Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Dap(Pentynoyl)-OH serves as an amino acid building block for introducing alkyne functions into peptide sequences by standard Fmoc/tBu protocols. The alkyne residue can be engaged for copper catalyzed click reaction with organic azides or with tetrazines for copper-free conjugations . Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W008689
-
N-Fmoc-6-Aminohexanoic acid
|
Biochemical Assay Reagents
|
Others
|
Fmoc-ε-Acp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W141961
-
-
- HY-126532
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
Fmoc-Val-Cit-PAB-Duocarmycin TM is a agent-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin TM, linked via Fmoc-Val-Cit-PAB.
|
-
- HY-W109214
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-Dap(Boc,Me)-OH is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of diaminopropionic acid containing peptide .
|
-
- HY-147104
-
|
Fluorescent Dye
|
Others
|
Fmoc-Lys(5-FITC)-OH is a marker for polypeptides or proteins. FITC is a fluorescence probe for the labeling of amines. FITC is a pH- and Cu 2+-sensitive fluorescence dye .
|
-
- HY-W008034
-
|
Amino Acid Derivatives
|
Cancer
|
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .
|
-
- HY-W046355
-
-
- HY-133404
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-aminooxy-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138546
-
|
Bacterial
|
Infection
|
Fmoc-Tpi-OH is a biologically active amino acid that can be used to synthesize antimicrobial peptide mimetics .
|
-
- HY-W008395
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-D-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-I1112
-
-
- HY-W041992
-
-
- HY-W041987
-
-
- HY-W141986
-
-
- HY-W010732
-
-
- HY-W039112
-
-
- HY-W112057
-
-
- HY-W337644
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-Homoarg(Et)2-OH hydrochloride is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of homoarginine containing peptide .
|
-
- HY-W007056
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .
|
-
- HY-W048730
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Phe(4-tBu)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize rOicPaPhe(p-Me)-NH(2) with platelet aggregation activation inhibitory activity .
|
-
- HY-Y1250S2
-
-
- HY-19821S1
-
Fmoc-L-isoleucine-13C6,15N
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Ile-OH- 13C6, 15N is the 13C and 15N labeled Fmoc-Ile-OH[1]. Fmoc-Ile-OH is an isoleucine derivative[2].
|
-
- HY-Y1250
-
Fmoc glycine; N-(9-Fluorenylmethoxycarbonyl)glycine; N-Fluorenylmethoxycarbonylglycine; NPC 14692; NSC 334288; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid
|
Amino Acid Derivatives
|
Others
|
Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds .
|
-
- HY-Y1169S1
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].
|
-
- HY-W008560
-
-
- HY-66024
-
-
- HY-W010714
-
-
- HY-W010888
-
-
- HY-W010924
-
-
- HY-W008156
-
-
- HY-W041986
-
-
- HY-W008866
-
-
- HY-Y1844
-
-
- HY-W043473
-
-
- HY-W008426
-
-
- HY-W013144
-
-
- HY-W041985
-
-
- HY-W022227
-
-
- HY-W010724
-
-
- HY-W010698
-
-
- HY-W140794
-
-
- HY-W348896
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Dha-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W106325
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-N-Me-D-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize somatostatin-dopamine chimeric analogs .
|
-
- HY-101064S
-
|
PPAR
|
Others
|
Fmoc-leucine- 13C is a 13C-labeled Boc-Glycine[1].
|
-
- HY-P3882
-
|
Amino Acid Derivatives
|
Neurological Disease
|
Fmoc-Ala-Glu-Gln-Lys-NH2 (AEQK) is a tetrapeptide. Fmoc-Ala-Glu-Gln-Lys-NH2 is the inactive control for Fmoc-Ala-Glu-Asn-Lys-NH2 (AENK) peptide inhibitor. AENK blocks proteolysis of UNC5C protein .
|
-
- HY-44980G
-
|
ADC Linker
|
Others
|
Fmoc-Gly-NH-CH2-acetyloxy GMP is a GMP grade Fmoc-Gly-NH-CH2-acetyloxy (HY-44980). Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).
|
-
- HY-W008555
-
-
- HY-W008922
-
-
- HY-W010997
-
-
- HY-139292
-
|
Amino Acid Derivatives
|
Cancer
|
Fmoc-NH-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-alcohol is extracted from patent WO2016030791, example comp 91 .
|
-
- HY-19318
-
|
ADC Linker
|
Cancer
|
Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker.
|
-
- HY-164732
-
|
ADC Linker
|
Cancer
|
Fmoc-Lys(DOTA)-OH is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W010986
-
-
- HY-79131S3
-
-
- HY-W008999
-
-
- HY-W009023
-
-
- HY-W016031
-
-
- HY-W010825
-
-
- HY-W010894
-
-
- HY-W008527
-
-
- HY-W008995
-
-
- HY-W008971
-
-
- HY-W013714
-
-
- HY-W010931
-
-
- HY-W010871
-
-
- HY-W010836
-
-
- HY-W010811
-
-
- HY-66026
-
-
- HY-66025
-
-
- HY-W013735
-
-
- HY-Y1250S1
-
-
- HY-153976
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
Fmoc-Gly3-VC-PAB-MMAE is a Drug-Linker Conjugates for ADC. Fmoc-Gly3-VC-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker .
|
-
- HY-135418
-
|
ADC Linker
|
Cancer
|
Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W023121
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W097109A
-
|
ADC Linker
|
Cancer
|
Fmoc-(D-Phe)-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P5299
-
-
- HY-156813
-
|
ADC Linker
|
Cancer
|
Fmoc-Val-Ala-aminomethyl acetate (Compound 58b) is an ADC Linker, and can be used for synthesis of ADCs .
|
-
- HY-PS0011
-
|
Drug Intermediate
|
Others
|
Fmoc-Gly-Wang resin is a resin containing a glycine protecting group and can be used for the synthesis of peptides .
|
-
- HY-W009204S1
-
-
- HY-79131S1
-
-
- HY-W008371S1
-
-
- HY-W009204S4
-
-
- HY-122456
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-122459
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126882
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140461
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140440
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040245
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-amino-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140441
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-aminooxy-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141102
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141101
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130907
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138330
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG5-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138434
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG14-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138720
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138721
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W143484
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-137002
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging .
|
-
- HY-W022281
-
-
- HY-W008529
-
-
- HY-W013740
-
-
- HY-W013745
-
-
- HY-W010770
-
-
- HY-W013769
-
-
- HY-W013749
-
-
- HY-46859
-
-
- HY-19318A
-
|
ADC Linker
|
Cancer
|
Fmoc-D-Val-Cit-PAB is a cleavable linker for antibody-agent-conjugation (ADC) .
|
-
- HY-19318B
-
|
ADC Linker
|
Cancer
|
Fmoc-D-Val-Cit-PAB is a cleavable linker for antibody-agent-conjugation (ADC) .
|
-
- HY-W013779
-
-
- HY-W045822
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys(Pal-Glu-OtBu)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-140460
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140462
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG20-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140463
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG23-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140464
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG36-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W013081
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Gln(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010856
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Orn(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W006886
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-(R)-2-(7-octenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize inhibitor peptides that combinatorially inactivate ErbB1, ErbB2, and ErbB3 .
|
-
- HY-W048700
-
-
- HY-151669
-
|
ADC Linker
|
Others
|
Fmoc-D-Aha-OH is a click chemistry reagent containing an azide . Fmoc-D-Aha-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138106
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .
|
-
- HY-79129
-
|
ADC Linker
|
Cancer
|
Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W013780S2
-
-
- HY-W013726
-
-
- HY-160072
-
|
Others
|
Cancer
|
Fmoc-NH-PEG2-NHS ester is an intermediate used in the synthesis of E-selectin antagonists [1] .
|
-
- HY-129361
-
-
- HY-W008997
-
-
- HY-W010957
-
-
- HY-W142008
-
-
- HY-W008996
-
-
- HY-W008972
-
-
- HY-W010974
-
-
- HY-W141945
-
-
- HY-W010927
-
-
- HY-W010926
-
-
- HY-W010838
-
-
- HY-W017617
-
-
- HY-W016028
-
-
- HY-W142086
-
-
- HY-W101718
-
|
Isotope-Labeled Compounds
ADC Linker
|
Cancer
|
Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody agent coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1].
|
-
- HY-104004
-
Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH
|
Amino Acid Derivatives
|
Cancer
|
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a agent for cancer.
|
-
- HY-W007941S
-
-
- HY-151842
-
|
ADC Linker
|
Others
|
Fmoc-EDA-N3 is a click chemistry reagent containing an azide group . Fmoc-EDA-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-44234
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140118
-
|
ADC Linker
|
Cancer
|
Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126353
-
|
ADC Linker
|
Cancer
|
Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136107
-
|
ADC Linker
|
Cancer
|
Fmoc-Phe-Lys(Trt)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136136
-
|
ADC Linker
|
Cancer
|
Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131833
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-139353
-
|
ADC Linker
|
Cancer
|
Fmoc-Phe-Lys(Boc)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W540122
-
-
- HY-PS0015
-
-
- HY-144628
-
|
ADC Linker
|
Cancer
|
Fmoc-Asn-Pro-Val-PABC-PNP (compound 6) is a potent ADC Linker .
|
-
- HY-151638
-
|
ADC Linker
|
Others
|
FMOC-3-azido-D-alanine is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-104004A
-
Fmoc-Ser-(GalNAc(Ac)3-beta-D)-OH; Fmoc-Ser[GalNAc(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-Gal)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative .
|
-
- HY-W145762
-
-
- HY-141103
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126880
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140442
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-aminooxy-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133470
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138123
-
|
Others
|
Others
|
Fmoc-Glu(OtBu)-OSu is used for synthesizing N3S chelators and double branched and triple branched carboxyl terminated polyethylene glycol reagents .
|
-
- HY-19318C
-
|
ADC Linker
|
Cancer
|
Fmoc-D-Val-D-Cit-PAB is a cleavable linker for antibody-agent-conjugation (ADC) .
|
-
- HY-W010982
-
-
- HY-Y1169S2
-
4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3; Fmoc-L-Asp(OtBu)-OH-d3
|
Isotope-Labeled Compounds
Amino Acid Derivatives
|
Others
|
Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-W007655
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-D-Lys(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-156825
-
-
- HY-P2396
-
-
- HY-P2400
-
-
- HY-P2405
-
-
- HY-P2390
-
-
- HY-P2393
-
-
- HY-P2398
-
-
- HY-P2409
-
-
- HY-P2410
-
-
- HY-P2386
-
-
- HY-P2385
-
-
- HY-164867
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-Dap(NBSD)-OH is a benzodiazole amino acid that can be used as a building block for constructing background-free peptide probes for fluorescence imaging .
|
-
- HY-W010850
-
-
- HY-W141820
-
-
- HY-114430
-
|
ADC Linker
|
Others
|
Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-400191
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-(d-Gly)-allyl propionate is a cleavable linker that can be used to synthesize Antibody-Drug Conjugates (ADCs).
|
-
- HY-141902S
-
-
- HY-P2402
-
-
- HY-129350
-
|
ADC Linker
|
Cancer
|
Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140119
-
|
ADC Linker
|
Cancer
|
Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130933
-
|
ADC Linker
|
Cancer
|
Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130175
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130364
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133062
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133063
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG8-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W055861
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151671
-
|
ADC Linker
|
Others
|
Fmoc-L-MeLys(N3)-OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys(N3)-OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry . Fmoc-L-MeLys(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-134681
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134715
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138320
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG36-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138331
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096094
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-44980
-
|
ADC Linker
|
Others
|
Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).
|
-
- HY-W729030
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Lys(biotinyl-e-aminocaproyl)-OH is a biotinylated biochemical assay reagent, that can be used to develop the ferrocene-based biosensor .
|
-
- HY-W100942
-
-
- HY-W008867
-
-
- HY-W008908
-
-
- HY-W141821
-
-
- HY-141464
-
Fmoc-Asn(Ac3AcNH-beta-Glc)-OH
|
Amino Acid Derivatives
|
Cancer
|
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET) .
|
-
- HY-151778
-
|
ADC Linker
|
Others
|
Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-43279
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs .
|
-
- HY-151687
-
|
ADC Linker
|
Others
|
Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-P2389
-
-
- HY-P2395
-
-
- HY-P2397
-
-
- HY-P2399
-
-
- HY-P2401
-
-
- HY-P2403
-
-
- HY-P2404
-
-
- HY-P2407
-
-
- HY-P2408
-
-
- HY-P2384
-
-
- HY-P2388
-
-
- HY-P2411
-
-
- HY-P2391
-
-
- HY-P2412
-
-
- HY-P2387
-
-
- HY-136106
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140013
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140465
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NMe-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-131955
-
|
ADC Linker
|
Cancer
|
Fmoc-aminooxy-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P2394
-
-
- HY-164181
-
-
- HY-W141907
-
-
- HY-W000434
-
Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007798S
-
-
- HY-151826
-
|
ADC Linker
|
Others
|
Fmoc-D-Lys(pentynoyl)-OH is a click chemistry reagent containing an azide group. Used to introduce alkyne functionality into peptides that can be further modified using Click-chemistry .
|
-
- HY-46346
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-Gly-NH-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-NH-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-136154
-
|
ADC Linker
|
Cancer
|
Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W749603
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) can be used for conjugation of peptides and radionuclides.
|
-
- HY-W141817
-
-
- HY-132099
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132110
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132111
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151660
-
|
ADC Linker
|
Others
|
Fmoc-D-Lys(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-D-Lys(N3)-OH can be used for the research of various biochemical . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151733
-
|
ADC Linker
|
Others
|
Fmoc-D-Dbu(N3)-OH is a click chemistry reagent containing an Azide . Fmoc-D-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-I1111S1
-
-
- HY-P3497
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
|
-
- HY-79648S
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Methylalanine-d3 is the deuterium labeled Trifloxystrobin. Trifloxystrobin (CGA 279202) is a fungicide, with EC50s of 23.0 μg/L and 1.7 μg/L for Daphnia magna neonate and embryos, respectively, after treatment for 48 h[1].
|
-
- HY-120773
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126881
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG2-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151663
-
Fmoc-Abu(3-N3)-OH (2R,3R)
|
ADC Linker
|
Others
|
Fmoc-Abu(3-N3) (Fmoc-Abu(3-N3)-OH) (2R,3R) is a click chemistry reagent containing an azide group. Fmoc-Abu(3-N3) (2R,3R) can be used for the research of various biochemical . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W008568
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-amino-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135029
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-PEG3-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140466
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG11-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140467
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W615153
-
-
- HY-W250408
-
-
- HY-151781
-
|
ADC Linker
|
Others
|
Fmoc-L-Dap(Poc)-OH is a click chemistry reagent containing an azide group. Amino acid building block suitable for side chain Click conjugation with standard protocols and together with tetrazine linkers in copper-free Click conjugation (Diels-Alder) .
|
-
- HY-141149
-
|
ADC Linker
|
Cancer
|
Fmoc-PEG4-Ala-Ala-Asn-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130941
-
|
ADC Linker
|
Cancer
|
Fmoc-N-bis-PEG3-NH-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136108
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly3-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-132988
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Tyr(3-F,tBu)-OH is a cyclic peptide compound with high membrane permeability and can specifically binds to a target molecule (extracted from patent WO2018225864A1) .
|
-
- HY-160714
-
|
ADC Linker
|
Cancer
|
Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH (Compound IM-3) is a cleavable ADC linker .
|
-
- HY-140340
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-pentanoic acid-NHS-SO3Na is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140668
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG-CH2COOH (MW 3400) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140669
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040231
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040238
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG2-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130167
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG9-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-P3497A
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
|
-
- HY-45669
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-W013780S
-
|
Isotope-Labeled Compounds
Autophagy
Bacterial
Antibiotic
|
Infection
|
Fmoc-Pro-OH-1- 13C is a 13C-labeled Sulfabenzamide. Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative ba
|
-
- HY-W044285
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-4-Aph(cBm)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active peptide mimetics, such as Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P)-D4Aph/D4Amf(Q)-Leu-ILys-Pro-DAla-NH2 with gonadotropin-releasing hormone (GnRH) antagonist activity .
|
-
- HY-141153
-
|
ADC Linker
|
Cancer
|
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a cleavable linker for synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-133471
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134682
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG5-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130077
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141151
-
|
ADC Linker
|
Cancer
|
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151679
-
|
ADC Linker
|
Others
|
Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition . Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-I1111S4
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-L-Val-OH- 15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].
|
-
- HY-151786
-
|
ADC Linker
|
Others
|
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W035378
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-49453
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-101064S4
-
-
- HY-Y1250S4
-
|
Fungal
|
Infection
Cancer
|
Fmoc-Gly-OH-1- 13C is a 13C-labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a
|
-
- HY-22062
-
-
- HY-W007706S
-
-
- HY-W145646
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-L-Ser((Ac)4-β-D-Glc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-136155
-
|
ADC Linker
|
Cancer
|
Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-79130
-
Benzeneacetic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-; (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]phenylethanoic acid; (S)-N-Fmoc-α-phenylglycine; N-9-Fluorenylmethoxycarbonyl-L-phenylglycine
|
Amino Acid Derivatives
|
Others
|
Fmoc-(S)-phenylglycine is a Glycine (HY-Y0966) derivative .
|
-
- HY-135821
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133361
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG15-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130870
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG11-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133362
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG16-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133363
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG19-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133364
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG25-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133365
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG30-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-79128S1
-
-
- HY-151825
-
|
ADC Linker
|
Others
|
Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .
|
-
- HY-W040135
-
-
- HY-W040246
-
-
- HY-114174
-
|
Amyloid-β
|
Neurological Disease
|
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing .
|
-
- HY-160069
-
|
PROTAC Linkers
|
Others
|
Fmoc-Gly-Gly-Gly-NH-PEG4-C2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
|
-
- HY-W096128
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG3-amide-CH2OCH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W008016S
-
-
- HY-151738
-
|
ADC Linker
|
Others
|
Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W013780S1
-
|
Isotope-Labeled Compounds
Fungal
|
Infection
|
Fmoc-Pro-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni
|
-
- HY-45545
-
|
Others
|
Others
|
Fmoc-gly-gly-ph-gly-nh-ch2-o-ch2cooh can be used to synthesize the ADC Linker, LND1067 .
|
-
- HY-I1111S2
-
-
- HY-156810
-
|
ADC Linker
|
Cancer
|
Fmoc-PEG4-GGFG-CH2-O-CH2-Cbz is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize active antibody conjugation molecules (ADC) .
|
-
- HY-49412
-
|
Others
|
Others
|
Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3 (compound DC-13-C) is an intermediate in the synthesis of Exatecan (HY-13631) derivatives .
|
-
- HY-151659
-
|
ADC Linker
|
Others
|
Fmoc-L-Lys(N3-Gly)-OH is a click chemistry reagent containing a lysine-containing azidoacetyl group building-block for SPPS and can be used for various biochemical studies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W002327S
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Asn(Trt)-OH- 13C4, 15N2 is a 15N-labeled and 13C-labled 4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole[1].
|
-
- HY-W250541
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH is an intermediate in the synthesis of ADC linker.The linker composed of Benzyl 2-cyclopropyl-2-hydroxyacetate can be coupled to Exatecan (HY-13631) and combined with antibodies (such as antibody hu2F7) .
|
-
- HY-151787
-
|
ADC Linker
|
Others
|
Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151829
-
|
ADC Linker
|
Others
|
Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-49463
-
|
ADC Linker
|
Neurological Disease
|
Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Gly-CH2-O-CH2-Cbz is an ADC linker that can be used in the synthesis of ADCs (such as Trastuzumab deruxtecan and U3-1402).
|
-
- HY-79647
-
N-(Fmoc-oxy)succinimide
|
Biochemical Assay Reagents
|
Others
|
N-(9-Fluorenylmethoxycarbonyloxy)succinimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y1250S6
-
Fmoc glycine-13C2,15N; N-(9-Fluorenylmethoxycarbonyl)glycine-13C2,15N; N-Fluorenylmethoxycarbonylglycine-13C2,15N; NPC 14692-13C2-15N; NSC 334288-13C2,15N; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid-13C2,15N
|
Isotope-Labeled Compounds
Influenza Virus
Bacterial
|
Infection
|
Fmoc-Gly-OH- 13C2, 15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
|
-
- HY-W072732
-
-
- HY-W010719
-
-
- HY-W048673
-
|
Amino Acid Derivatives
|
Others
|
Boc-Dap(Boc)-OH is an amino acid derivative with a Boc protecting group and can be used in the synthesis of primary amides .
|
-
- HY-P0232
-
-
- HY-W048199
-
-
- HY-W006937
-
Boc-p-amino-D-Phe(Fmoc)-OH; Boc-D-phe(4-NH-Fmoc)-OH
|
Amino Acid Derivatives
|
Others
|
Boc-D-(4-fmoc)-aminophenylalanine (Boc-p-amino-D-Phe(Fmoc)-OH) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with gonadotropin-releasing hormone antagonist activity .
|
-
- HY-W419374
-
|
Amino Acid Derivatives
|
Others
|
ivDde-Lys(Fmoc)-OH is a derivative of amino acid with protecting groups. ivDde-Lys(Fmoc)-OH can be used for peptide synthesis .
|
-
- HY-133472
-
|
PROTAC Linkers
|
Cancer
|
DBCO-NHCO-PEG3-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG3-Fmoc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-150850S
-
-
- HY-W548477
-
|
Amino Acid Derivatives
|
Others
|
H-Lys(Fmoc)-OH hydrochloride is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize diacylated GLP-1 derivatives with antidiabetic activity .
|
-
- HY-W009049S
-
-
- HY-W116478S
-
-
- HY-W005144
-
-
- HY-W008196
-
-
- HY-W108867
-
|
Others
|
|
N-Fmoc-ethylenediamine hydrobromide is an important chemical reagent with the activity of promoting organic synthesis reactions. N-Fmoc-ethylenediamine hydrobromide is often used in the synthesis of peptides and other amino compounds in the field of biochemistry because it can effectively protect the amino group and provide good reactivity. The application of N-Fmoc-ethylenediamine hydrobromide helps to improve the efficiency and selectivity of synthesis and becomes a key component in organic synthesis.
|
-
- HY-157052
-
|
PROTAC Linkers
|
Others
|
exo-BCN-Fmoc-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-Fmoc-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-129362
-
|
ADC Linker
|
Cancer
|
Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
- HY-79132
-
-
- HY-78733
-
-
- HY-47858
-
-
- HY-P4277
-
|
Glyoxalase (GLO)
|
Others
|
N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a Ki value of 0.32 mM .
|
-
- HY-W006923
-
-
- HY-W002327S1
-
-
- HY-W088097
-
-
- HY-138318
-
|
PROTAC Linkers
|
Cancer
|
DBCO-PEG3-amide-N-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG3-amide-N-Fmoc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W036160
-
|
Amino Acid Derivatives
|
Others
|
N-Fmoc-O-ethyl-L-homoserine is an homoserine derivative, can be used in cyclic peptide compounds synthesis, as a reducing reagent .
|
-
- HY-W008575
-
|
Others
|
Others
|
N-Fmoc-N-methoxy-3-aminopropionic acid, a Weinreb amide linker, is a protein cross-linking agent .
|
-
- HY-151748
-
|
ADC Linker
|
Others
|
N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W142171
-
-
- HY-W048205
-
|
Amino Acid Derivatives
|
Others
|
N6-Diazo-L-Fmoc-lysine is an active compand and can be used in a variety of chemical studies. N6-Diazo-L-Fmoc-lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151843
-
|
ADC Linker
|
Others
|
N3-L-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group . N3-L-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140848
-
|
PROTAC Linkers
|
Cancer
|
Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG3-L-alanine-Fmoc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W074914
-
-
- HY-151715
-
|
ADC Linker
|
Others
|
N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-152978
-
|
Nucleoside Antimetabolite/Analog
|
Others
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-W142062
-
|
Amino Acid Derivatives
|
Others
|
cis-Fmoc-Pro(4-N3)-OH is a proline derivative . cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151749
-
|
ADC Linker
|
Others
|
N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W540023
-
|
ADC Linker
|
Cancer
|
Endo-BCN-Fmoc-L-Lysine is a linker containing the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-W039102
-
|
Amino Acid Derivatives
|
Cancer
|
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells .
|
-
- HY-131082
-
|
ADC Linker
|
Cancer
|
(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151681
-
cis-4-Azido-N-Fmoc-D-proline
|
ADC Linker
|
Others
|
(2R,4R)-Fmoc-D-Pro(4-N3)-OH (cis-4-Azido-N-Fmoc-D-proline) is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-140846
-
|
PROTAC Linkers
|
Cancer
|
N-Fmoc-N'-(azido-PEG4)-L-Lysine is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N-Fmoc-N'-(azido-PEG4)-L-Lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-136058
-
|
ADC Linker
|
Cancer
|
N3-PEG4-amido-Lys(Fmoc)-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG4-amido-Lys(Fmoc)-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151814
-
|
ADC Linker
|
Others
|
(2S,4S)-Fmoc-L-Pro(4-NHPoc)-OH is a click chemistry reagent containing an azide group.
|
-
- HY-152979
-
|
DNA/RNA Synthesis
|
Others
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-131087
-
|
ADC Linker
|
Cancer
|
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140847
-
|
PROTAC Linkers
|
Cancer
|
N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is an alkyl/ether and PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-Y0912
-
N-HBTU
|
Biochemical Assay Reagents
|
Others
|
HBTU is a coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis .
|
-
- HY-153195
-
|
Drug Intermediate
|
Cancer
|
Tetra-O-acetyl-β-D-galactopyranosyl-Ph-CH2OH-Fmoc can be used as conjugates to prepare antibody drug conjugates (ADCs) .
|
-
- HY-152873
-
|
Nucleoside Antimetabolite/Analog
|
Others
|
Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-151689
-
|
ADC Linker
|
Others
|
(2S,3R)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group. (2S,3R)-Fmoc-Abu(3-N3)-OH can be used for the research of various biochemical . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151850
-
|
ADC Linker
|
Others
|
(2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide . (2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151828
-
|
ADC Linker
|
Others
|
N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-131296
-
|
Others
|
Inflammation/Immunology
|
5-A-RU-PABC-Val-Cit-Fmoc is the proagent of 5-A-RU . 5-A-RU, a precursor of bacterial Riboflavin, is a mucosal-associated invariant T (MAIT) cells activator. 5-A-RU forms potent MAIT-activating antigens via non-enzymatic reactions with small molecules, such as glyoxal and methylglyoxal, which are derived from other metabolic pathways .
|
-
- HY-153196
-
|
ADC Linker
|
Others
|
Tetra-O-acetyl-β-D-galactopyranosyl-Ph-CH2-(4-nitrophenyl)carbonate-Fmoc (Example 2.28.6) is an ADC linker that can be used to synthesize antibody-conjugated active molecules (ADCs) .
|
-
- HY-151779
-
|
ADC Linker
|
Others
|
N3-L-Dab(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151734
-
|
ADC Linker
|
Others
|
(2R,3S)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151762
-
|
ADC Linker
|
Others
|
(2R,4S)-Fmoc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-152983
-
|
DNA/RNA Synthesis
|
Others
|
2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-129480
-
|
Drug Intermediate
|
Others
|
Vertilmicin sulfate combines with FMOC-Cl to form the Vertilmicin-FMOC-Cl adduct, and can be used for the determination of glucosamine sulfate in plasma .
|
-
- HY-W047799
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Phe(4-CONH2)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a small-sized HTLV-I protease inhibitor with hydrophilicity .
|
-
- HY-D0300S1
-
-
- HY-W015339S
-
-
- HY-W134007S
-
-
- HY-W286743S
-
-
- HY-Z3421S
-
-
- HY-W321016S
-
-
- HY-W002071S
-
-
- HY-Y0869S
-
-
- HY-116285S
-
-
- HY-124547S
-
-
- HY-148463
-
|
ADC Linker
|
Cancer
|
MP-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-148464
-
|
ADC Linker
|
Cancer
|
MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P2439
-
|
Neurokinin Receptor
|
Others
|
MEN 10208 is a neurokinin A antagonist prepared by solid phase synthesis. The Fmoc strategy has more advantages than the Boc strategy in its preparation, and can obtain products with higher yield and purity.
|
-
- HY-141833
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
Bi-Mc-VC-PAB-MMAE consists ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Bi-Mc-VC-PAB-MMAE is a agent-linker conjugate for ADC.
|
-
- HY-W089230
-
N,N'-Di-tert-butoxycarbonyl-L-histidine
|
Amino Acid Derivatives
|
Others
|
Boc-His(Boc)-OH (N,N'-Di-tert-butoxycarbonyl-L-histidine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize the dodecapeptide α-mating factor of Saccharomyces cerevisiae .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-19318G
-
|
Fluorescent Dye
|
Fmoc-Val-Cit-PAB GMP is a GMP grade Fmoc-Val-Cit-PAB (HY-19318). Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker.
|
-
- HY-78921AG
-
|
Fluorescent Dye
|
Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131833G
-
|
Fluorescent Dye
|
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-44980G
-
|
Fluorescent Dye
|
Fmoc-Gly-NH-CH2-acetyloxy GMP is a GMP grade Fmoc-Gly-NH-CH2-acetyloxy (HY-44980). Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).
|
Cat. No. |
Product Name |
Type |
-
- HY-W008963
-
Nα-Fmoc-D-tryptophan; Fmoc-D-Trp-OH
|
Biochemical Assay Reagents
|
Fmoc-D-Trp-OH (Nα-Fmoc-D-tryptophan) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W002327
-
|
Biochemical Assay Reagents
|
Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .
|
-
- HY-W008205
-
Fmoc-L-Hydroxyproline
|
Biochemical Assay Reagents
|
Fmoc-Hyp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008689
-
N-Fmoc-6-Aminohexanoic acid
|
Biochemical Assay Reagents
|
Fmoc-ε-Acp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008034
-
|
Drug Delivery
|
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .
|
-
- HY-22295
-
|
Biochemical Assay Reagents
|
Fmoc-4-aminobutanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-19318G
-
|
Biochemical Assay Reagents
|
Fmoc-Val-Cit-PAB GMP is a GMP grade Fmoc-Val-Cit-PAB (HY-19318). Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker.
|
-
- HY-78921AG
-
|
Biochemical Assay Reagents
|
Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W747366
-
-
- HY-131833G
-
|
Biochemical Assay Reagents
|
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-44980G
-
|
Biochemical Assay Reagents
|
Fmoc-Gly-NH-CH2-acetyloxy GMP is a GMP grade Fmoc-Gly-NH-CH2-acetyloxy (HY-44980). Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).
|
-
- HY-W013081
-
|
Biochemical Assay Reagents
|
Fmoc-Gln(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010856
-
|
Biochemical Assay Reagents
|
Fmoc-Orn(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007655
-
|
Biochemical Assay Reagents
|
Fmoc-D-Lys(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W729030
-
|
Biochemical Assay Reagents
|
Fmoc-Lys(biotinyl-e-aminocaproyl)-OH is a biotinylated biochemical assay reagent, that can be used to develop the ferrocene-based biosensor .
|
-
- HY-W749603
-
|
Chelators
|
Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) can be used for conjugation of peptides and radionuclides.
|
-
- HY-W145646
-
|
Biochemical Assay Reagents
|
Fmoc-L-Ser((Ac)4-β-D-Glc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-79647
-
N-(Fmoc-oxy)succinimide
|
Biochemical Assay Reagents
|
N-(9-Fluorenylmethoxycarbonyloxy)succinimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W007052
-
-
- HY-W010712
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .
|
-
- HY-P5037
-
|
Peptides
|
Others
|
Fmoc-Gly-Pro-Hyp-OH is a tripeptide that can be used in peptide synthesis .
|
-
- HY-P5037A
-
|
Peptides
|
Others
|
Fmoc-Gly-Pro-Hyp-OH TFA is a tripeptide that can be used in peptide synthesis .
|
-
- HY-P5962
-
|
Peptides
|
Others
|
Fmoc-Gly-Pro-Hyp(OtBu)-OH (TFA) is a tripeptide that can be used in peptide synthesis .
|
-
- HY-P5045
-
|
Peptides
|
Inflammation/Immunology
Cancer
|
Fmoc-Thr(GalNAc(Ac)3-β-D)-OH inhibits cancer cell growth, through targeting intricate cancer-specific pathways while simultaneously strengthening immunologic response .
|
-
- HY-W052227
-
-
- HY-W013152
-
-
- HY-P2392
-
-
- HY-W013123
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Phe(4-CF3)-OH is Phenylalanine derivative. Fmoc-D-Phe(4-CF3)-OH can be used for the research of peptide inhibitors of protein-protein interactions .
|
-
- HY-Y1636
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
|
-
- HY-Y1169
-
4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-W072147
-
Fmoc-L-Ser-OMe
|
Amino Acid Derivatives
|
Others
|
Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .
|
-
- HY-W008386
-
-
- HY-W013083
-
-
- HY-W008064
-
Fmoc-L-Citrulline
|
Amino Acid Derivatives
|
Cancer
|
Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif .
|
-
- HY-W004101
-
-
- HY-W022255
-
D-Fmoc-glutamic acid
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Glu-OH (D-Fmoc-glutamic acid) is a derivative of glutamate, can be used to prepare supramolecular hydrogels .
|
-
- HY-W048722
-
Fmoc-D-2-Thienylalanine
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Thi-OH (Fmoc-D-2-Thienylalanine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize AS-Z-P with thrombin inhibitory activity .
|
-
- HY-W142161
-
Fmoc-MeHis(Trt)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-N-Me-His(Trt)-OH (Fmoc-MeHis(Trt)-OH) is a is an amino acid derivative containing amino and carboxyl groups. Fmoc-N-Me-His(Trt)-OH for the synthesis of Fmoc-MeHis (Trt) -Leu-OH .
|
-
- HY-I1111
-
-
- HY-W048674
-
Fmoc-O-acetyl-L-serine
|
Amino Acid Derivatives
|
Infection
|
Fmoc-Ser(Ac)-OH (Fmoc-O-acetyl-L-serine) is a Serine derivative. Fmoc-Ser(Ac)-OH can be used for the preparation of broad-spectrum coronavirus membrane fusion inhibitor .
|
-
- HY-W048209
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Lys(Palmitoyl)-OH is a Fmoc-amino acid with long alkyl chains. Fmoc-Lys(Palmitoyl)-OH can be used for peptide synthesis .
|
-
- HY-19821
-
-
- HY-W010895
-
-
- HY-W013162
-
-
- HY-W010893
-
-
- HY-W011020
-
-
- HY-W048718
-
Fmoc-D-α-t-butylglycine
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Tle-OH (Fmoc-D-α-t-butylglycine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize chelating agents that can form a single stereoisomer-enriched form after coordination with metal centers .
|
-
- HY-W338516
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-Homoarginine hydrochloride is a derivative of amino acid with protecting groups. Fmoc-L-Homoarginine hydrochloride can be used for synthesis of homoarginine containing peptide .
|
-
- HY-W013751
-
N-Fmoc-glycyl-L-valine
|
Peptides
|
Others
|
Fmoc-Gly-Val-OH (N-Fmoc-glycyl-L-valine) is a glycyl valine derivative, can be used for the synthesis of drugs or other compounds .
|
-
- HY-W097054
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-cysteic acid is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize triarylsulfonium compounds for radiolabeling of peptides .
|
-
- HY-P10715
-
|
Peptides
|
Inflammation/Immunology
Cancer
|
Fmoc-KCRGDK is a self-assembling peptide that can be used to prepare hydrogels and assist in drug delivery for immune checkpoint inhibitors. Fmoc-KCRGDK can be applied in cancer immunotherapy research .
|
-
- HY-W009118
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-5-Ava-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize fatty acid-based dimeric peptides with PSD-95 inhibitory activity .
|
-
- HY-W022223
-
-
- HY-W011021
-
-
- HY-W041988
-
|
Bacterial
|
Infection
|
Fmoc-Glu-OMe, a glutamic acid derivative, shows antibacterial activity and gelation property in AgNO3 solution. Fmoc-Glu-OMe is a mouldable wound healing biomaterial .
|
-
- HY-W013154
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Tic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as the biotinylated derivative of the opioid receptor antagonist TIPP .
|
-
- HY-W048825
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Ala-Ala-OH (3) is a self-assemble fluorenylmethoxycarbonyl-dipeptide, which is a smaller amphiphilic building blocks consists dipeptides linked to fluore nylmethoxycarbonyl (Fmoc). Fmoc-Ala-Ala-OH can be used as scaffold materials in 3D cell culture .
|
-
- HY-W008688
-
-
- HY-W011084
-
-
- HY-W013190
-
-
- HY-W009003
-
-
- HY-W009005
-
-
- HY-W009085
-
-
- HY-W009088
-
-
- HY-W010793
-
-
- HY-W007020
-
-
- HY-W007720
-
-
- HY-W008176
-
- HY-W008475
-
- HY-W008696
-
- HY-W041982
-
- HY-W010959
-
- HY-W011000
-
- HY-W011081
-
- HY-W011135
-
- HY-W008360
-
- HY-W041991
-
- HY-W141948
-
- HY-79648
-
- HY-79131
-
- HY-W019028
-
- HY-22297
-
- HY-W009204
-
- HY-W009151
-
- HY-W013780
-
- HY-W010758
-
- HY-W010922
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists .
|
- HY-W008876
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II .
|
- HY-W041989
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Oic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg 10]HOE 140, which has bradykinin B1 antagonist activity .
|
- HY-W048671
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted research .
|
- HY-W011002
-
- HY-W010880
-
- HY-W016032
-
- HY-157248
-
- HY-W101305
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Pen(Acm)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize chemically modified cyclic peptides containing cell adhesion recognition (CAR) sequences .
|
- HY-W019032
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .
|
- HY-164166
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Sar-Sar-Sar-OH is a small molecule polypeptide composed of four sarcosine residues, in which the N-terminus of the peptide chain is protected by Fmoc. Fmoc-Sar-Sar-Sar-OH can be used for peptide synthesis or synthesis of drug-peptide ligand conjugates .
|
- HY-W004864
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-(S)-2-(4-pentenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active secretin analogs .
|
- HY-W011210
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-W008371
-
- HY-W048739
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .
|
- HY-W141987
-
- HY-W142030
-
- HY-79128
-
- HY-W041983
-
- HY-W011342
-
- HY-W010839
-
- HY-W041984
-
- HY-W008024
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release .
|
- HY-W009006
-
- HY-W009124
-
- HY-134852
-
- HY-137950
-
- HY-W097163
-
- HY-22296
-
- HY-W010721
-
- HY-W010782
-
- HY-W141946
-
- HY-W005815
-
- HY-W141985
-
- HY-W025807
-
- HY-W007108
-
- HY-W007706
-
- HY-W007941
-
- HY-W008016
-
- HY-W008072
-
- HY-W008869
-
- HY-W008872
-
- HY-W008958
-
- HY-W008986
-
- HY-W008926
-
- HY-W008273
-
- HY-W008256
-
- HY-W008075
-
- HY-W010962
-
- HY-W010964
-
- HY-W010965
-
- HY-W011026
-
- HY-W011089
-
- HY-W013118
-
- HY-W013143
-
- HY-W013145
-
- HY-W013185
-
- HY-W011126
-
- HY-W013659
-
- HY-W010976
-
- HY-W041990
-
- HY-W040024
-
- HY-W007942
-
- HY-W002436
-
- HY-W010943
-
- HY-W010862
-
- HY-W010830
-
- HY-W010794
-
- HY-W010734
-
- HY-W009119
-
- HY-W007798
-
- HY-W142115
-
- HY-W008021
-
- HY-W010729
-
- HY-P4198
-
- HY-W111226
-
|
Amyloid-β
Amino Acid Derivatives
|
Cardiovascular Disease
|
Fmoc-His(3-Me)OH derives Histidine-associating compounds with biological activity. Fmoc-His(3-Me)OH, with Fmoc-citrulline-OH, Fmoc-His(1-Me)-OH together, forms tri-peptides and shows vasodilating effect with EC50s of 2.7-4.7 mM in 1.0 mM Phenylephrine (PE)-contracted aorta rings. Fmoc-His(3-Me)OH (resin) also makes Methyl-His-Gly-Lys (His(3-Me)-Gly-Lys), thus acts as an [Ca 2+]i inhibitor. Fmoc-His(3-Me)OH methylates NAHIS02, making it unable to block the Alzheimer's Aβ channel .
|
- HY-W013153
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Tic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg 10]HOE 140, which has bradykinin B1 antagonist activity .
|
- HY-W048697
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand .
|
- HY-W141961
-
- HY-W109214
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-Dap(Boc,Me)-OH is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of diaminopropionic acid containing peptide .
|
- HY-W046355
-
- HY-W729138
-
|
Peptides
|
Others
|
Fmoc-D-homoArg(Et)2-OH (hydrochloride) is a Fmoc-protected derivative of D-Homoarginine (HArg) that renders peptides and proteins resistant to proteolysis by trypsin. Fmoc-D-homoArg(Et)2-OH (hydrochloride) can be used as a cleavable ADC linker to synthesize antibody-drug conjugates (ADCs) .
|
- HY-W008395
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-D-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-W041992
-
- HY-W041987
-
- HY-W141986
-
- HY-W010732
-
- HY-W039112
-
- HY-W048733
-
|
Peptides
|
Others
|
Fmoc-Asu(OtBu)-OH is a peptide intermediate and can be used in peptide synthesis.
|
- HY-W097232
-
|
Peptides
|
Others
|
Fmoc-Aph(Hor)-OH is a peptide intermediate and can be used in peptide synthesis.
|
- HY-W283704
-
|
Peptides
|
Others
|
Fmoc-(Dmb)Ala-OH is a peptide intermediate and can be used in peptide synthesis.
|
- HY-W419324
-
|
Peptides
|
Others
|
Fmoc-Aph(Cbm)-OH is a peptide intermediate and can be used in peptide synthesis.
|
- HY-W419989
-
|
Peptides
|
Others
|
Fmoc-Asu(Oall)-OH is a peptide intermediate and can be used in peptide synthesis.
|
- HY-W112057
-
- HY-W337644
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-Homoarg(Et)2-OH hydrochloride is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of homoarginine containing peptide .
|
- HY-W007056
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .
|
- HY-W048730
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Phe(4-tBu)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize rOicPaPhe(p-Me)-NH(2) with platelet aggregation activation inhibitory activity .
|
- HY-Y1250
-
Fmoc glycine; N-(9-Fluorenylmethoxycarbonyl)glycine; N-Fluorenylmethoxycarbonylglycine; NPC 14692; NSC 334288; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid
|
Amino Acid Derivatives
|
Others
|
Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds .
|
- HY-W008560
-
- HY-66024
-
- HY-W010714
-
- HY-W010888
-
- HY-W010924
-
- HY-W008156
-
- HY-W041986
-
- HY-W008866
-
- HY-Y1844
-
- HY-W043473
-
- HY-W008426
-
- HY-W013144
-
- HY-W041985
-
- HY-W022227
-
- HY-W010724
-
- HY-W010698
-
- HY-W140794
-
- HY-W015987
-
Fmoc-NH2
|
Peptides
|
Others
|
9-Fluorenylmethyl carbamate (Fmoc-NH2) is an amide compound with an Fmoc protecting group, which can be used as a photobase initiator to prepare organosilane-based proton exchange membranes .
|
- HY-W106325
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-N-Me-D-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize somatostatin-dopamine chimeric analogs .
|
- HY-P3882
-
|
Amino Acid Derivatives
|
Neurological Disease
|
Fmoc-Ala-Glu-Gln-Lys-NH2 (AEQK) is a tetrapeptide. Fmoc-Ala-Glu-Gln-Lys-NH2 is the inactive control for Fmoc-Ala-Glu-Asn-Lys-NH2 (AENK) peptide inhibitor. AENK blocks proteolysis of UNC5C protein .
|
- HY-W008922
-
- HY-W010997
-
- HY-W008999
-
- HY-W009023
-
- HY-W016031
-
- HY-W010825
-
- HY-W010894
-
- HY-W008527
-
- HY-W008995
-
- HY-W008971
-
- HY-W013714
-
- HY-W010931
-
- HY-W010871
-
- HY-W010836
-
- HY-W010811
-
- HY-66026
-
- HY-66025
-
- HY-W013735
-
- HY-P5299
-
- HY-PS0011
-
|
Drug Intermediate
|
Others
|
Fmoc-Gly-Wang resin is a resin containing a glycine protecting group and can be used for the synthesis of peptides .
|
- HY-PS0002
-
|
Peptides
|
Others
|
Fmoc-Ala-Wang resin is a resin containing an alanine amino protecting group and can be used for peptide synthesis .
|
- HY-137002
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging .
|
- HY-W022281
-
- HY-W008529
-
- HY-W013740
-
- HY-W013745
-
- HY-W010770
-
- HY-W013769
-
- HY-W013749
-
- HY-W013779
-
- HY-W006886
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-(R)-2-(7-octenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize inhibitor peptides that combinatorially inactivate ErbB1, ErbB2, and ErbB3 .
|
- HY-W048700
-
- HY-138106
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .
|
- HY-W013726
-
- HY-W008997
-
- HY-W010957
-
- HY-W142008
-
- HY-W008996
-
- HY-W008972
-
- HY-W010974
-
- HY-W141945
-
- HY-W010927
-
- HY-W010926
-
- HY-W010838
-
- HY-W017617
-
- HY-W016028
-
- HY-W142086
-
- HY-PS0005
-
|
Peptides
|
Others
|
Fmoc-Arg(Pbf)-Wang resin is a resin containing an arginine protecting group and can be used for the synthesis of peptides .
|
- HY-PS0015
-
- HY-104004A
-
Fmoc-Ser-(GalNAc(Ac)3-beta-D)-OH; Fmoc-Ser[GalNAc(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-Gal)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative .
|
- HY-W145762
-
- HY-W010982
-
- HY-W018847
-
|
Peptides
|
Others
|
Fmoc-(R)-2-(pentenyl)Ala-OH is a peptide intermediate and can be used in peptide synthesis.
|
- HY-W101772
-
|
Peptides
|
Others
|
Fmoc-D-Phe(4-NHBoc)-OH is a peptide intermediate and can be used in peptide synthesis.
|
- HY-P2396
-
- HY-P2400
-
- HY-P2405
-
- HY-P2390
-
- HY-P2393
-
- HY-P2398
-
- HY-P2409
-
- HY-P2410
-
- HY-P2386
-
- HY-P2385
-
- HY-W010850
-
- HY-W141820
-
- HY-P2402
-
- HY-W100942
-
- HY-W008867
-
- HY-W008908
-
- HY-W141821
-
- HY-P2389
-
- HY-P2395
-
- HY-P2397
-
- HY-P2399
-
- HY-P2401
-
- HY-P2403
-
- HY-P2404
-
- HY-P2407
-
- HY-P2408
-
- HY-P2384
-
- HY-P2388
-
- HY-P2411
-
- HY-P2391
-
- HY-P2412
-
- HY-P2387
-
- HY-P2394
-
- HY-W141907
-
- HY-W141817
-
- HY-P3497
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
|
- HY-P3497A
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
|
- HY-W044285
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-4-Aph(cBm)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active peptide mimetics, such as Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P)-D4Aph/D4Amf(Q)-Leu-ILys-Pro-DAla-NH2 with gonadotropin-releasing hormone (GnRH) antagonist activity .
|
- HY-22062
-
- HY-79130
-
Benzeneacetic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-; (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]phenylethanoic acid; (S)-N-Fmoc-α-phenylglycine; N-9-Fluorenylmethoxycarbonyl-L-phenylglycine
|
Amino Acid Derivatives
|
Others
|
Fmoc-(S)-phenylglycine is a Glycine (HY-Y0966) derivative .
|
- HY-114174
-
|
Amyloid-β
|
Neurological Disease
|
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing .
|
- HY-W072732
-
- HY-W010719
-
- HY-W048673
-
|
Amino Acid Derivatives
|
Others
|
Boc-Dap(Boc)-OH is an amino acid derivative with a Boc protecting group and can be used in the synthesis of primary amides .
|
- HY-P0232
-
- HY-23861
-
Fmoc-N,N-dimethyl-L-Glutamine
|
Peptides
|
Others
|
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N5,N5-dimethyl-L-glutamine is a glutamine derivative .
|
- HY-W048199
-
- HY-W006937
-
Boc-p-amino-D-Phe(Fmoc)-OH; Boc-D-phe(4-NH-Fmoc)-OH
|
Amino Acid Derivatives
|
Others
|
Boc-D-(4-fmoc)-aminophenylalanine (Boc-p-amino-D-Phe(Fmoc)-OH) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with gonadotropin-releasing hormone antagonist activity .
|
- HY-W419374
-
|
Amino Acid Derivatives
|
Others
|
ivDde-Lys(Fmoc)-OH is a derivative of amino acid with protecting groups. ivDde-Lys(Fmoc)-OH can be used for peptide synthesis .
|
- HY-W548477
-
|
Amino Acid Derivatives
|
Others
|
H-Lys(Fmoc)-OH hydrochloride is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize diacylated GLP-1 derivatives with antidiabetic activity .
|
- HY-W005144
-
- HY-W008196
-
- HY-W092202
-
|
Peptides
|
Others
|
Dde-Lys(Fmoc)-OH is a peptide intermediate and can be used in peptide synthesis.
|
- HY-79132
-
- HY-78733
-
- HY-P4277
-
|
Glyoxalase (GLO)
|
Others
|
N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a Ki value of 0.32 mM .
|
- HY-W006923
-
- HY-W088097
-
- HY-W036160
-
|
Amino Acid Derivatives
|
Others
|
N-Fmoc-O-ethyl-L-homoserine is an homoserine derivative, can be used in cyclic peptide compounds synthesis, as a reducing reagent .
|
- HY-W142171
-
- HY-W048205
-
|
Amino Acid Derivatives
|
Others
|
N6-Diazo-L-Fmoc-lysine is an active compand and can be used in a variety of chemical studies. N6-Diazo-L-Fmoc-lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W074914
-
- HY-W141923
-
- HY-W142062
-
|
Amino Acid Derivatives
|
Others
|
cis-Fmoc-Pro(4-N3)-OH is a proline derivative . cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W039102
-
|
Amino Acid Derivatives
|
Cancer
|
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells .
|
- HY-W047799
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Phe(4-CONH2)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a small-sized HTLV-I protease inhibitor with hydrophilicity .
|
- HY-P2439
-
|
Neurokinin Receptor
|
Others
|
MEN 10208 is a neurokinin A antagonist prepared by solid phase synthesis. The Fmoc strategy has more advantages than the Boc strategy in its preparation, and can obtain products with higher yield and purity.
|
- HY-W089230
-
N,N'-Di-tert-butoxycarbonyl-L-histidine
|
Amino Acid Derivatives
|
Others
|
Boc-His(Boc)-OH (N,N'-Di-tert-butoxycarbonyl-L-histidine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize the dodecapeptide α-mating factor of Saccharomyces cerevisiae .
|
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-101064S3
-
|
Fmoc-leucine-d10 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].
|
-
-
- HY-W007720S
-
|
Fmoc-Ser-OH-d3 is the deuterium labeled Fmoc-Ser-OH.
|
-
-
- HY-W007720S1
-
|
Fmoc-Ser-OH- 15N is the 15N labeled Fmoc-Ser-OH.
|
-
-
- HY-W008371S2
-
|
Fmoc-Met-OH-d3 is the deuterium labeled Fmoc-Met-OH.
|
-
-
- HY-Y1250S5
-
|
Fmoc-Gly-OH- 13C2 is a 13C-labeled Fmoc-Gly-OH (HY-Y1250). Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds .
|
-
-
- HY-79131S5
-
|
Fmoc-Phe-OH- 13C is the 13C labeled Fmoc-Phe-OH[1]. Fmoc-Phe-OH is a phenylalanine derivative[2].
|
-
-
- HY-19821S
-
|
Fmoc-Ile-OH- 15N is the 15N labeled Fmoc-Ile-OH[1].
|
-
-
- HY-W009204S5
-
|
Fmoc-Ala-OH- 13C3 is a 13C-labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-ind
|
-
-
- HY-79131S4
-
|
Fmoc-Phe-OH-d8 is the deuterium labeled Fmoc-Phe-OH.
|
-
-
- HY-W009204S8
-
|
Fmoc-Ala-OH-d is the deuterium labeled Fmoc-Ala-OH[1].
|
-
-
- HY-W013780S3
-
|
Fmoc-Pro-OH-d3 is the deuterium labeled Fmoc-Pro-OH.
|
-
-
- HY-W052227S
-
|
Fmoc-DL-Ala-OH-d is the deuterium labeled DL-Alanine-2-N-fmoc.
|
-
-
- HY-I1111S
-
|
Fmoc-L-Val-OH-d8 is a deuterium labeled Fmoc-L-Val-OH. Fmoc-L-Val-OH is a kind of protect amino acids[1].
|
-
-
- HY-W009204S
-
|
Fmoc-Ala-OH- 15N is the 15N labeled Fmoc-Ala-OH[1].
|
-
-
- HY-W008371S
-
|
Fmoc-Met-OH- 15N is the 15N labeled Fmoc-Met-OH[1].
|
-
-
- HY-Y1250S
-
|
Fmoc-Gly-OH- 15N is the 15N labeled Fmoc-Gly-OH[1].
|
-
-
- HY-79131S2
-
|
Fmoc-Phe-OH-d5 is the deuterium labeled Fmoc-Phe-OH[1].
|
-
-
- HY-W009204S6
-
|
Fmoc-Ala-OH-d4 is the deuterium labeled Fmoc-Ala-OH[1].
|
-
-
- HY-Y1250S3
-
|
Fmoc-Gly-OH- 13C is a 13C-labeled Fmoc-Phe-OH[1].
|
-
-
- HY-W007941S1
-
|
Fmoc-Ser(tBu)-OH- 15N is the 15N labeled Fmoc-Ser(tBu)-OH[1]. Fmoc-Ser(tBu)-OH is a serine derivative[2].
|
-
-
- HY-101064S1
-
|
Fmoc-leucine- 13C6, 15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity
|
-
-
- HY-W007798S1
-
|
Fmoc-Cys(Trt)-OH-d2 is the deuterium labeled Fmoc-Cys(Trt)-OH. Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative[1].
|
-
-
- HY-Y1636S1
-
|
Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].
|
-
-
- HY-W008072S
-
|
Fmoc-D-Ala-OH-d3 is the deuterium labeled Fmoc-D-Ala-OH.
|
-
-
- HY-W011026S
-
|
Fmoc-D-Phe-OH-d5 is the deuterium labeled Fmoc-D-Phe-OH.
|
-
-
- HY-W011026S1
-
|
Fmoc-D-Phe-OH-d8 is the deuterium labeled Fmoc-D-Phe-OH.
|
-
-
- HY-W010712S1
-
|
Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
|
-
-
- HY-W009204S3
-
|
Fmoc-Ala-OH-3- 13C is the 13C labeled Fmoc-Ala-OH[1].
|
-
-
- HY-W009204S2
-
|
Fmoc-Ala-OH-1- 13C is the 13C labeled Fmoc-Ala-OH[1].
|
-
-
- HY-79131S
-
|
Fmoc-Phe-OH- 13C6 is a 13C-labeled Fmoc-Ala-OH[1].
|
-
-
- HY-Y0134S
-
|
Fmoc-Glu(OtBu)-OH- 15N is a 15N-labeled Fmoc-L-Val-OH[1].
|
-
-
- HY-I1111S3
-
|
Fmoc-L-Val-OH- 13C5 is a 13C-labeled Fmoc-Gly-OH[1].
|
-
-
- HY-101064S2
-
|
Fmoc-leucine-d3 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].
|
-
-
- HY-79128S
-
|
Fmoc-L-Lys (Boc)-OH- 15N2 is a 15N-labeled Fmoc-L-Lys (Boc)-OH (HY-79128). Fmoc-L-Lys (Boc)-OH is a lysine derivative .
|
-
-
- HY-Y1250S2
-
|
Fmoc-Gly-OH-2,2-d2 is the deuterium labeled Fmoc-Gly-OH-2,2[1].
|
-
-
- HY-19821S1
-
|
Fmoc-Ile-OH- 13C6, 15N is the 13C and 15N labeled Fmoc-Ile-OH[1]. Fmoc-Ile-OH is an isoleucine derivative[2].
|
-
-
- HY-Y1169S1
-
|
Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].
|
-
-
- HY-101064S
-
|
Fmoc-leucine- 13C is a 13C-labeled Boc-Glycine[1].
|
-
-
- HY-79131S3
-
|
Fmoc-Phe-OH- 15N is a 15N-labeled Propoxur.
|
-
-
- HY-Y1250S1
-
|
Fmoc-Gly-OH-2- 13C, 15N is the 13C, 15N labeled Fmoc-Gly-OH-2[1].
|
-
-
- HY-W009204S1
-
|
Fmoc-Ala-OH-3,3,3-d3 is the deuterium labeled Fmoc-Ala-OH-3,3,3[1].
|
-
-
- HY-79131S1
-
|
Fmoc-Phe-OH- 13C9, 15N is a 15N-labeled and 13C-labled Fmoc-Ala-OH[1].
|
-
-
- HY-W008371S1
-
|
Fmoc-Met-OH- 13C5, 15N is a 15N-labeled and 13C-labled Fmoc-L-Val-OH[1].
|
-
-
- HY-W009204S4
-
|
Fmoc-Ala-OH- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-Aib-OH[1].
|
-
-
- HY-W013780S2
-
|
Fmoc-Pro-OH- 15N is a 15N-labeled Glycine ethyl ester monohydrochloride[1].
|
-
-
- HY-W007941S
-
|
Fmoc-Ser(tBu)-OH- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-L-Lys (Boc)-OH[1].
|
-
-
- HY-Y1169S2
-
|
Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
-
- HY-141902S
-
|
FMOC-L-Glutamic Acid- 13C5, 15N-5-t-butyl ester is the 13C and 15N labeled FMOC-L-Glutamic Acid-5-t-butyl ester[1].
|
-
-
- HY-W007798S
-
|
Fmoc-Cys(Trt)-OH-1,2,3- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-Phe-OH[1].
|
-
-
- HY-I1111S1
-
|
Fmoc-L-Val-OH-1- 13C is a 13C-labeled Carbaryl. Carbaryl is used chiefly as an insecticide[1].
|
-
- HY-79648S
-
|
Fmoc-Methylalanine-d3 is the deuterium labeled Trifloxystrobin. Trifloxystrobin (CGA 279202) is a fungicide, with EC50s of 23.0 μg/L and 1.7 μg/L for Daphnia magna neonate and embryos, respectively, after treatment for 48 h[1].
|
-
- HY-W013780S
-
|
Fmoc-Pro-OH-1- 13C is a 13C-labeled Sulfabenzamide. Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative ba
|
-
- HY-I1111S4
-
|
Fmoc-L-Val-OH- 15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].
|
-
- HY-101064S4
-
|
Fmoc-leucine- 15N is a 15N-labeled and 13C-labled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine ence
|
-
- HY-Y1250S4
-
|
Fmoc-Gly-OH-1- 13C is a 13C-labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a
|
-
- HY-W007706S
-
|
Fmoc-Thr(tBu)-OH- 13C4, 15N is a 15N-labeled and 13C-labled 2-Acetamidobenzamide[1].
|
-
- HY-79128S1
-
|
Fmoc-L-Lys (Boc)-OH- 13C6, 15N2 is a 15N-labeled and 13C-labled Triclabendazole.
|
-
- HY-W008016S
-
|
Fmoc-Tyr(tBu)-OH- 13C9, 15N is a 15N-labeled and 13C-labled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
|
-
- HY-W013780S1
-
|
Fmoc-Pro-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni
|
-
- HY-I1111S2
-
|
Fmoc-L-Val-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pirimicarb. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an
|
-
- HY-W002327S
-
|
Fmoc-Asn(Trt)-OH- 13C4, 15N2 is a 15N-labeled and 13C-labled 4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole[1].
|
-
- HY-Y1250S6
-
|
Fmoc-Gly-OH- 13C2, 15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
|
-
- HY-150850S
-
|
DL-Leucine-N-FMOC-d10 is the deuterium labeled DL-Leucine-N-FMOC[1].
|
-
- HY-W009049S
-
|
D-Methionine-N-fmoc-d3 is the deuterium labeled D-Methionine-N-fmoc.
|
-
- HY-W116478S
-
|
D-Leucine-N-fmoc-d10 is the deuterium labeled D-Leucine-N-fmoc.
|
-
- HY-W002327S1
-
|
L-Asparagine-N-Fmoc,N-beta-trityl- 15N2 is a 15N-labeled L-Asparagine-N-Fmoc,N-beta-trityl .
|
-
- HY-D0300S1
-
|
Leucomalachite green-d6 is the deuterium labeled Fmoc-Gly-OH[1].
|
-
- HY-W015339S
-
|
Octanoate- 13C (sodium) is a 13C-labeled Fmoc-Gly-OH[1].
|
-
- HY-W134007S
-
|
Hexadecanoate- 13C (potassium) is a 13C-labeled Fmoc-L-Val-OH[1].
|
-
- HY-W286743S
-
|
CML-d4 is the deuterium labeled Fmoc-L-Lys (Boc)-OH[1].
|
-
- HY-Z3421S
-
|
Vonoprazan-d3 (fumarate) is the deuterium labeled Fmoc-Cys(Trt)-OH[1].
|
-
- HY-W321016S
-
|
SWEP-d3 is the deuterium labeled Fmoc-Tyr(tBu)-OH[1].
|
-
- HY-W002071S
-
|
2-Quinoxalinecarboxylic acid-d4 is the deuterium labeled Fmoc-Pro-OH[1].
|
-
- HY-Y0869S
-
|
4-Methoxybenzylamine-d3 is the deuterium labeled Fmoc-Ser(tBu)-OH[1].
|
-
- HY-116285S
-
|
n-Octyl β-D-glucopyranoside-d24 is the deuterium labeled Fmoc-L-Val-OH[1].
|
-
- HY-124547S
-
|
2,4-D methyl ester-d3 is the deuterium labeled Fmoc-Trp-OH[1].
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-W011210
-
|
|
Alkynes
|
Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W008395
-
|
|
Alkynes
|
Fmoc-D-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-D-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151637
-
|
|
Alkynes
|
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures . Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151695
-
N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine
|
|
Alkynes
|
Fmoc-L-Lys(Pryoc)-OH (N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine) is a click chemistry reagent containing an azide group .
|
-
- HY-151640
-
|
|
Azide
|
Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151780
-
|
|
Alkynes
|
Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Dap(Pentynoyl)-OH serves as an amino acid building block for introducing alkyne functions into peptide sequences by standard Fmoc/tBu protocols. The alkyne residue can be engaged for copper catalyzed click reaction with organic azides or with tetrazines for copper-free conjugations . Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151669
-
|
|
Azide
|
Fmoc-D-Aha-OH is a click chemistry reagent containing an azide . Fmoc-D-Aha-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151842
-
|
|
Azide
|
Fmoc-EDA-N3 is a click chemistry reagent containing an azide group . Fmoc-EDA-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151638
-
|
|
Azide
|
FMOC-3-azido-D-alanine is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151671
-
|
|
Azide
|
Fmoc-L-MeLys(N3)-OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys(N3)-OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry . Fmoc-L-MeLys(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151778
-
|
|
Azide
|
Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151687
-
|
|
Azide
|
Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151826
-
|
|
Alkynes
|
Fmoc-D-Lys(pentynoyl)-OH is a click chemistry reagent containing an azide group. Used to introduce alkyne functionality into peptides that can be further modified using Click-chemistry .
|
-
- HY-132099
-
|
|
PROTAC Synthesis
Azide
|
Fmoc-N-amido-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132110
-
|
|
PROTAC Synthesis
Azide
|
Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132111
-
|
|
PROTAC Synthesis
Azide
|
Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151660
-
|
|
Azide
|
Fmoc-D-Lys(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-D-Lys(N3)-OH can be used for the research of various biochemical . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151733
-
|
|
Azide
|
Fmoc-D-Dbu(N3)-OH is a click chemistry reagent containing an Azide . Fmoc-D-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151663
-
Fmoc-Abu(3-N3)-OH (2R,3R)
|
|
Azide
|
Fmoc-Abu(3-N3) (Fmoc-Abu(3-N3)-OH) (2R,3R) is a click chemistry reagent containing an azide group. Fmoc-Abu(3-N3) (2R,3R) can be used for the research of various biochemical . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151781
-
|
|
Alkynes
|
Fmoc-L-Dap(Poc)-OH is a click chemistry reagent containing an azide group. Amino acid building block suitable for side chain Click conjugation with standard protocols and together with tetrazine linkers in copper-free Click conjugation (Diels-Alder) .
|
-
- HY-151679
-
|
|
Azide
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Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition . Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151786
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Azide
Alkynes
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Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-136155
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ADC Synthesis
Azide
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Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151825
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Alkynes
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Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .
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- HY-151738
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Azide
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Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151659
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Azide
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Fmoc-L-Lys(N3-Gly)-OH is a click chemistry reagent containing a lysine-containing azidoacetyl group building-block for SPPS and can be used for various biochemical studies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-151787
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Azide
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Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-151829
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Azide
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Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-133472
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DBCO
PROTAC Synthesis
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DBCO-NHCO-PEG3-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG3-Fmoc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-157052
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PROTAC Synthesis
BCN
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exo-BCN-Fmoc-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-Fmoc-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-138318
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PROTAC Synthesis
DBCO
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DBCO-PEG3-amide-N-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG3-amide-N-Fmoc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-151748
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Azide
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N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-W048205
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Azide
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N6-Diazo-L-Fmoc-lysine is an active compand and can be used in a variety of chemical studies. N6-Diazo-L-Fmoc-lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151843
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Azide
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N3-L-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group . N3-L-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140848
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PROTAC Synthesis
Azide
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Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG3-L-alanine-Fmoc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151715
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Azide
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N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-W142062
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Azide
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cis-Fmoc-Pro(4-N3)-OH is a proline derivative . cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151749
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Azide
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N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-W540023
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BCN
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Endo-BCN-Fmoc-L-Lysine is a linker containing the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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- HY-131082
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ADC Synthesis
Azide
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(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151681
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cis-4-Azido-N-Fmoc-D-proline
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Azide
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(2R,4R)-Fmoc-D-Pro(4-N3)-OH (cis-4-Azido-N-Fmoc-D-proline) is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-140846
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Azide
PROTAC Synthesis
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N-Fmoc-N'-(azido-PEG4)-L-Lysine is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N-Fmoc-N'-(azido-PEG4)-L-Lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-136058
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ADC Synthesis
Azide
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N3-PEG4-amido-Lys(Fmoc)-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG4-amido-Lys(Fmoc)-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151814
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Alkynes
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(2S,4S)-Fmoc-L-Pro(4-NHPoc)-OH is a click chemistry reagent containing an azide group.
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- HY-140847
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PROTAC Synthesis
Azide
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N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is an alkyl/ether and PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151689
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Azide
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(2S,3R)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group. (2S,3R)-Fmoc-Abu(3-N3)-OH can be used for the research of various biochemical . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-151850
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Azide
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(2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide . (2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151828
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Azide
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N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-151779
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Azide
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N3-L-Dab(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-151734
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Azide
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(2R,3S)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-151762
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Azide
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(2R,4S)-Fmoc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No. |
Product Name |
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Classification |
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- HY-152978
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Nucleoside Phosphoramidites
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2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-152979
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Nucleoside Phosphoramidites
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2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-152873
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Nucleosides and their Analogs
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Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152983
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Nucleoside Phosphoramidites
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2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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