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Results for "

phospholipase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Phospholipase (126) 5-HT Receptor (2) Acyltransferase (1) Adenosine Receptor (1) Akt (1) Antibiotic (2) Apoptosis (7) Autophagy (4) Bacterial (2) Biochemical Assay Reagents (1) Calcium Channel (1) COX (4) DAGL (2) Dopamine Receptor (3) Endogenous Metabolite (9) ERK (3) FAAH (1) Ferroptosis (1) Fluorescent Dye (1) Fungal (3) HIV Protease (2) Integrin (5) Interleukin Related (1) Isotope-Labeled Compounds (1) Leukotriene Receptor (1) Liposome (3) Lipoxygenase (2) mAChR (1) MAGL (2) mGluR (1) P2Y Receptor (1) Phosphatase (4) Phosphodiesterase (PDE) (1) PI3K (1) PKA (1) PKC (2) Prostaglandin Receptor (3) Reactive Oxygen Species (2) Reverse Transcriptase (1) TNF Receptor (1) TRP Channel (2) Virus Protease (1)
By Research Areas:	Cancer (38) Cardiovascular Disease (11) Endocrinology (2) Infection (11) Inflammation/Immunology (71) Metabolic Disease (21) Neurological Disease (27)
Oligonucleotides:	Phospholipids (4)

165

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: Phospholipase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2812

Phospholipase D, Streptomyces chromofuscus PLD	Phospholipase	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Phospholipase D, Streptomyces chromofuscus (PLD) is an enzyme of the phospholipase superfamily, which widely exists in bacteria, yeast, plants, animals and viruses, and is often used in biochemical research. Phospholipase D can catalyze the hydrolysis of phosphodiester bonds in glycerophospholipids to produce phosphatidic acid and soluble choline. Phospholipase D is involved in a variety of disease-related processes, including diabetes, atherogenesis, obesity, tumorigenesis, immune response, and neuroendocrine function .

HY-P3029

Phospholipase A2 PLA2	Phospholipase	Others
Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA). Phospholipase A2 is a member of the class of heat-stable, calcium-dependent enzymes, is often used in biochemical studies .

HY-148388

N-Stearoylsphingomyelin N-Stearoyl-D-sphingomyelin	Phospholipase	Cancer
N-Stearoylsphingomyelin (N-Stearoyl-D-sphingomyelin) is a sphingolipid, which can inhibit Phospholipase Cδ1 (PLCδ1) .

HY-101195

DL-erythro-Dihydrosphingosine	PKC Phospholipase	Cancer
DL-erythro-Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2) .

HY-P2812B

Phospholipase D, cabbage	Phospholipase	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Phospholipase D, cabbage is an enzyme of the phospholipase superfamily. Phospholipase D, cabbage is widely found in bacteria, yeast, plants, animals and viruses and is often used in biochemical research. Phospholipase D, cabbage can catalyze the hydrolysis of the phosphodiester bond of glycerophospholipids to produce phosphatidic acid and soluble choline. Phospholipase D, cabbage is involved in a variety of disease-related processes, including diabetes, atherosclerosis, obesity, tumorigenesis, immune response and neuroendocrine function .

HY-P2812A

Phospholipase D, peanut	Endogenous Metabolite	Metabolic Disease
Phospholipase D, peanut is an important signaling enzyme in mammalian cells. Phospholipase D, peanut catalyzes the hydrolysis of phosphatidylcholine to produce phosphatidic acid (PA) and choline .

HY-P2817

Phospholipase C PLCs	Others	Others
Phospholipase C (PLCs) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P3029A

Phospholipase A2, Crotalus adamanteus Venom PLA2, Crotalus adamanteus Venom	Others	Others
Phospholipase A2, Crotalus adamanteus Venom (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA). Phospholipase A2, Crotalus adamanteus Venom is a member of the class of heat-stable, calcium-dependent enzymes, is often used in biochemical studies .

HY-19920

AVX001 AKH-217	Phospholipase	Inflammation/Immunology
AVX001 is an inhibitor of phospholipase A2 (cPLA2α) that can be used in the research of psoriasis .

HY-116671

Folipastatin	Phospholipase	Others
Folipastatin is a potent inhibitor of phospholipase A2 with an IC₅₀ of 39 μM. Folipastatin is a new depsidone compound from Aspergillus unguis .

HY-162368

cPLA2α-IN-2	Phospholipase	Others
cPLA2α-IN-2 (Compound 122) is an inhibitor of cytosolic phospholipase A₂α (cPLA₂α) .

HY-111376

Pyrrophenone 3 Publications Verification	Phospholipase	Cardiovascular Disease Inflammation/Immunology
Pyrrophenone is a potent and specific cytosolic phospholipase A₂α (cPLA₂α) inhibitor with an IC₅₀ value of 4.2 nM .

HY-155342

A3373	Phospholipase	Inflammation/Immunology
A3373, a novel chemical inhibitor of *Phospholipase* D1 (PLD1) and PLD2, with IC₅₀ of 325 nM and 15.15?μM, respectively, inhibits LPS-induced immune response and plays important roles in autoimmune arthritis, bone demineralization and osteoclastogenesis .

HY-127008

N-Butylfluorescein	Fluorescent Dye	Others
N-Butylfluorescein is an alkyl-substituted fluorescein, can be used for synthesis of fluorogenic substrates for assaying phosphatidylinositol-specific phospholipase C .

HY-23909

7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid DEDA	Phospholipase	Inflammation/Immunology
7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a *phospholipase* inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A₂ (PLA₂) (IC₅₀ = 16 µM) and snake venom PLA₂ (IC₅₀ = 14 µM) .

HY-115855

Ro 31-4639	Phospholipase	Inflammation/Immunology
Ro 31-4639 is a potent phospholipase A2 inhibitor with an IC₅₀ of 1.5 μM .

HY-155343

A4333	Phospholipase	Cancer
A4333 is biotinylated compound of A3373 (HY-155342) that inhibits *Phospholipase* D1 (PLD1), but not PLD2. A4333 plays an important role in antitumor activity .

HY-W396889

(R)-N-(1-Hydroxypropan-2-yl)palmitamide	Phospholipase	Inflammation/Immunology
(R)-N-(1-Hydroxypropan-2-yl)palmitamide (compound 24) is a substrate analog inhibitor of phospholipase A2 .

HY-108607

PACOCF3 Palmityltrifluoromethylketone	Phospholipase	Inflammation/Immunology
PACOCF3 (Palmityltrifluoromethylketone) is a selective phospholipase A2 inhibitor with an IC₅₀ of 3.8 μM. PACOCF3 alters Ca ²⁺ signaling in renal tubular cells .

HY-114457

Phosphatidylinositol 4,5-bisphosphate L-alpha-Phosphatidylinositol-4,5-bisphosphate	PI3K	Others
Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger .

HY-P10658

ARF1 (2-17)	Phospholipase	Others
ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis .

HY-133148

Lp-PLA2-IN-2	Phospholipase	Inflammation/Immunology
Lp-PLA2-IN-2 is a potent and selective *lipoprotein-associated phospholipase* A2 (Lp-PLA2) inhibitor, with an IC₅₀** 0f 120 nM for recombinant human Lp-PLA2 .

HY-136177

Tris(2,4-di-tert-butylphenyl)phosphate	Phospholipase	Inflammation/Immunology
Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for *secretory Phospholipase* A₂ (sPLA₂**) through molecular docking .

HY-107393

LY-311727	Phospholipase	Inflammation/Immunology
LY-311727 is a potent *secretory non-pancreatic phospholipase* A₂ (sPLA₂)** inhibitor (IC₅₀ <1 μM for group IIA sPLA₂). sPLA₂ is an important proinflammatory enzyme .

HY-116730

CHS-111	Reactive Oxygen Species	Others
CHS-111 is a benzyl indazole inhibitor of superoxide anion O ^2- generation. CHS-111 inhibits the cell migration, and reduces the formyl-Met-Leu-Phe- but not phorbol ester-stimulated phospholipase D activity, with the IC₅₀ of 3.9 μM .

HY-19151

Fuzapladib IS-741	Integrin Phospholipase	Inflammation/Immunology
Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .

HY-19151C

Fuzapladib calcium IS-741 calcium	Integrin Phospholipase	Inflammation/Immunology
Fuzapladib calcium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib calcium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib calcium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .

HY-14952

Giripladib PLA-695	Phospholipase	Inflammation/Immunology Cancer
Giripladib (PLA-695) is a indole-based inhibitor of *cytosolic phospholipase* A₂ (cPLA₂)**. Giripladib can be used for osteoarthritis and breast cancer research .

HY-118725

Luffariellolide	Phospholipase	Inflammation/Immunology
Luffariellolide is an inhibitor of human synovial fluid phospholipase A2 (HSF-PLA2) (IC₅₀=5 μM). Luffariellolide effectively inhibits phorbol ester (PMA)-induced ear edema (ED₅₀=50 μg/ear) .

HY-P2705

Mastoparan X	Endogenous Metabolite	Others
Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells .

HY-145384

ROC-0929	Phospholipase	Inflammation/Immunology
ROC-0929 (compound 13a) is a potent and selective inhibitor of *secreted phospholipases* A₂ (sPLA₂s) with an IC₅₀ of 80 nM, specially targeting hGX. ROC-0929 inhibits the phosphorylation of ERK1/2 and p-38. Secreted phospholipases A2 (sPLA2s)** are a family of disulfide-rich, Ca ²⁺-dependent enzymes that hydrolyze the sn-2 position of glycero-phospholipids to release a fatty acid and a lysophospholipid. ROC-0929 has the potential for researching inflammation related diseases .

HY-142669

Lp-PLA2-IN-4	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-4 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-4 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 38) .

HY-142670

Lp-PLA2-IN-5	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-5 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-5 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 32) .

HY-142779

Lp-PLA2-IN-11	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145) .

HY-70072

D609 5+ Cited Publications	Phospholipase	Infection Inflammation/Immunology Cancer
D609, an antitumoural xanthate, is a specific and competitive *phosphatidyl choline-specific phospholipase* C (PC-PLC) inhibitor with a K_i** of 6.4 μM. D609 is an antioxidative protector and has antiviral and anti-inflammatory activity .

HY-142778

Lp-PLA2-IN-10	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-10 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-10 has the potential for the research of neurodegenerative-related diseases such as Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), or cardiovascular diseases including atherosclerosis (extracted from patent WO2022001881A1, compound 4) .

HY-116301

CAY10502	Phospholipase	Inflammation/Immunology
CAY10502 is a potent, calcium-dependent *cytosolic phospholipase* A2 α (cPLA₂α) inhibitor with an IC₅₀** of 4.3 nM for isolated enzyme. CAY10502 can be used in the research of retinopathy and inflammatory diseases .

HY-100983

Protein kinase inhibitor H-7 dihydrochloride	PKC	Cancer
Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) .

HY-19151A

Fuzapladib sodium IS-741 sodium	Integrin Phospholipase	Inflammation/Immunology
Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .

HY-19151B

Fuzapladib potassium IS-741 potassium	Integrin Phospholipase	Inflammation/Immunology
Fuzapladib (IS-741) potassium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib potassium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib potassium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .

HY-136177R

Tris(2,4-di-tert-butylphenyl)phosphate (Standard)	Phospholipase	Inflammation/Immunology
Tris(2,4-di-tert-butylphenyl)phosphate (Standard) is the analytical standard of Tris(2,4-di-tert-butylphenyl)phosphate. This product is intended for research and analytical applications. Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A2 (sPLA2) through molecular docking .

HY-116018

FKGK11	Phospholipase	Neurological Disease Inflammation/Immunology Cancer
FKGK11 is a potent and selective inhibitor of GVIA iPLA2 (Group VIA calcium-independent phospholipase A2). FKGK11 can be used for the research of ovarian cancer and neurological disorders such as peripheral nerve injury and multiple sclerosis .

HY-W100403

Choline tosylate Choline p-toluenesulfonate	Phospholipase	Cancer
Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG) .

HY-N1773

5,7,3'-Tri-O-methyl (-)-epicatechin	Others	Cancer
5,7,3' -tri-O-Methyl (-)-epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-)-epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-)-epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer .

HY-115062

MJ33 lithium salt	Phospholipase	Metabolic Disease
MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6 .

HY-145653

GSK2647544	Phospholipase	Cardiovascular Disease Neurological Disease Inflammation/Immunology
GSK2647544 is an orally available, selective inhibitor of Lp-PLA2. Lipoprotein-associated phospholipase (Lp-PLA2) is a calcium-independent phospholipase A2 with proinflammatory activities that is primarily secreted by monocyte-derived macrophages .

HY-N9480

Vinaxanthone SM-345431	Phospholipase Bacterial	Infection Cancer
Vinaxanthone (SM-345431) is a potent and selective semaphorin3A, phospholipase C (PLC) and FabI inhibitor, with IC₅₀s of 0.1-0.2 μM and 0.9 mM for semaphorin3A and FabI. Vinaxanthone inhibits the substrate (t-o-NAC thioester) and the cofactor (NADPH) with K_is of 3.1 μM and 1.0 μM, respectively. Vinaxanthone can be used to handle infections caused by multidrug-resistant pathogens .

HY-129944

MJ33-OH	Phospholipase	Inflammation/Immunology
MJ33-OH is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6 .

HY-129944A

MJ33-OH lithium	Phospholipase	Inflammation/Immunology
MJ33-OH lithium is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6 .

HY-125157

Me-Indoxam	Phospholipase	Inflammation/Immunology
Me-Indoxam is a potent and cell-impermeable secreted phospholipase A₂ (sPLA₂) inhibitor .

Cat. No.	Product Name	Type

HY-D1647

7-Hydroxycoumarinyl-γ-linolenate	Chromogenic Substrates
7-Hydroxycoumarinyl-γ-linolenate is a cytosolic phospholipase A₂ (cPLA₂) fluorogenic substrate. 7-Hydroxycoumarinyl-γ-linolenate can be used to monitor the enzymatic activity of cPLA₂ .

HY-100045

p-Nitrophenyl phosphorylcholine 4-Nitrophenylphosphorylcholine; 4-Nitrophenylphosphorylcholine; O-(4-Nitrophenylphosphoryl)choline	Fluorescent Dyes/Probes
p-Nitrophenyl phosphorylcholine (4-Nitrophenylphosphorylcholine) is a chromogenic substrate that is used to measure phospholipase C (PLC) activity. Hydrolysis of p-nitrophenylphosphorylcholine by PLC results in the liberation of p-nitrophenol, which can be measured at 405 nm at pH 7.2-7.5.

HY-W713925

Diheptanoyl Thio-PC	Dyes
Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).1 Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP.

Cat. No.	Product Name	Type

HY-100168

BAPTA

Maximum Cited Publications

25 Publications Verification

Chelators

BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca ²⁺ release from intracellular stores or influx via Ca ²⁺-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca ²⁺ chelators .

HY-100168B

BAPTA tetrapotassium

Maximum Cited Publications

25 Publications Verification

Chelators

BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca ²⁺ release from intracellular stores or influx via Ca ²⁺-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca ²⁺ chelators .

HY-W100403

Choline tosylate Choline p-toluenesulfonate	Enzyme Substrates
Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG) .

HY-142980

Dioleoylphosphatidylglycerol DOPG	Drug Delivery
Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) .

HY-W127380

Arachidonoyl thio-PC

Enzyme Substrates

Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.

HY-157718

1,2-Di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine

Drug Delivery

1,2-Di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine is a surfactant that has the activity of promoting liposome formation. 1,2-Di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine can effectively study the biological effects of ceramide and ceramide phosphate. 1,2-Di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine shows important application in the determination of phospholipase A activity of lecithin-cholesterol acyltransferase in ether matrix.

Cat. No.	Product Name	Target	Research Area

HY-P2705

Mastoparan X	Endogenous Metabolite	Others
Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells .

HY-P10658

ARF1 (2-17)	Phospholipase	Others
ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis .

HY-P10053

sPLA2-IIA Inhibitor	Peptides	Metabolic Disease
sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids .

HY-113560

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

HY-P10447

Plipastatin A1 Fengycin IX; SNA-60-367-3	Phospholipase	Inflammation/Immunology
Plipastatin A1 is a lipopeptide with enzyme inhibitory and immunosuppressive activities. Plipastatin A1 is found in Bacillus cereus and inhibits phospholipase A2 (PLA2), PLC, and PLD .

HY-P1834

MARCKS Peptide(151-175), Phosphorylated	Peptides	Inflammation/Immunology
MARCKS Peptide(151-175), Phosphorylated is a phosphorylated peptide corresponding to the basic effector domain of myristoylated alanine-rich protein kinase C substrate protein (MARCKS). Phosphorylation of MARCKS Peptide (151-175) reverses its inhibition of phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) .

HY-P3906

Melittin free acid	Fungal Apoptosis Phospholipase Reactive Oxygen Species	Infection
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-136177

Tris(2,4-di-tert-butylphenyl)phosphate	Natural Products Verbenaceae Source classification Plants Inflammation/Immunology Disease Research Fields Vitex negundo Linn.	Phospholipase
Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for *secretory Phospholipase* A₂ (sPLA₂**) through molecular docking .

HY-W019838

D-Erythro-dihydrosphingosine Sphinganine (d18:0)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Phospholipase
D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A₂α (cPLA₂α) activity.

HY-N7036

Rhamnetin	Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Amberboa moschata (L.) DC. Umbelliferae Plants Inflammation/Immunology Disease Research Fields	Phospholipase
Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity .

HY-N1450

Aristolochic acid C	Structural Classification Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields Cancer	Phospholipase
Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A₂ (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .

HY-116671

Folipastatin	Monophenols Microorganisms Classification of Application Fields Source classification Other Diseases Phenols Disease Research Fields	Phospholipase
Folipastatin is a potent inhibitor of phospholipase A2 with an IC₅₀ of 39 μM. Folipastatin is a new depsidone compound from Aspergillus unguis .

HY-114457

Phosphatidylinositol 4,5-bisphosphate L-alpha-Phosphatidylinositol-4,5-bisphosphate	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	PI3K
Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger .

HY-118725

Luffariellolide	Natural Products Classification of Application Fields Animals Source classification Disease Research Fields Inflammation/Immunology	Phospholipase
Luffariellolide is an inhibitor of human synovial fluid phospholipase A2 (HSF-PLA2) (IC₅₀=5 μM). Luffariellolide effectively inhibits phorbol ester (PMA)-induced ear edema (ED₅₀=50 μg/ear) .

HY-136177R

Tris(2,4-di-tert-butylphenyl)phosphate (Standard)	Natural Products Verbenaceae Source classification Plants Vitex negundo Linn.	Phospholipase
Tris(2,4-di-tert-butylphenyl)phosphate (Standard) is the analytical standard of Tris(2,4-di-tert-butylphenyl)phosphate. This product is intended for research and analytical applications. Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A2 (sPLA2) through molecular docking .

HY-N1773

5,7,3'-Tri-O-methyl (-)-epicatechin	Structural Classification Machilus thunbergii Sieb. et Zucc. Flavonoids Flavanols Source classification Plants Lauraceae	Others
5,7,3' -tri-O-Methyl (-)-epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-)-epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-)-epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer .

HY-N9480

Vinaxanthone SM-345431	Structural Classification Microorganisms Xanthones Classification of Application Fields Source classification Phenols Disease Research Fields Cancer	Phospholipase Bacterial
Vinaxanthone (SM-345431) is a potent and selective semaphorin3A, phospholipase C (PLC) and FabI inhibitor, with IC₅₀s of 0.1-0.2 μM and 0.9 mM for semaphorin3A and FabI. Vinaxanthone inhibits the substrate (t-o-NAC thioester) and the cofactor (NADPH) with K_is of 3.1 μM and 1.0 μM, respectively. Vinaxanthone can be used to handle infections caused by multidrug-resistant pathogens .

HY-N8610

Uralsaponin D	Triterpenes Structural Classification Leguminosae Glycyrrhiza inflata Batal. Terpenoids Source classification Plants	Phosphatase
Uralsaponin D is a saponin that can be isolated from Glycyrrhiza inflata. Uralsaponin D inhibits phospholipase A2 (PLA₂) with an IC₅₀ value of 32.2 μM .

HY-141570

Lyso-PAF C-16	Microorganisms Source classification	Others
Lyso-PAF C-16 is a substrate of lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD). Lyso-PAF C-16 selective acetylates with arachidonic acid .

HY-W012595A

trans-Benzylideneacetone trans-Benzalacetone	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Inflammation/Immunology Disease Research Fields	Phospholipase
trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant .

HY-N7036R

Rhamnetin (Standard)	Flavonols Structural Classification Flavonoids Source classification Phenols Polyphenols Amberboa moschata (L.) DC. Umbelliferae Plants	Phospholipase
Rhamnetin (Standard) is the analytical standard of Rhamnetin. This product is intended for research and analytical applications. Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity .

HY-N1450R

Aristolochic acid C (Standard)	Structural Classification Monophenols other families Source classification Phenols Plants	Phospholipase
Aristolochic acid C (Standard) is the analytical standard of Aristolochic acid C. This product is intended for research and analytical applications. Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .

HY-N2330

Lipstatin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
Lipstatin is a pancreatic lipase inhibitor (IC₅₀=0.14 μM), whose structure is closely related to the known inhibitor, Esterastin. Lipstatin inhibits the absorption of triglycerides without affecting the absorption of oleic acid. Lipstatin has no inhibitory effects on other pancreatic enzymes, such as phospholipase A2 and trypsin (<200 μM) .

HY-W654264

2-Methylbutyrylcarnitine chloride	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Integrin
2-Methylbutyrylcarnitine (chloride) is a gut microbial metabolite which binds to integrin α2β1 in platelets, potentiating cytosolic phospholipase A2 (cPLA2) activation and platelet hyperresponsiveness. 2-Methylbutyrylcarnitine (chloride) enhances platelet hyperreactivity and thrombus formation in mice. 2-Methylbutyrylcarnitine (chloride) is a branched-chain acylcarnitine .

HY-B0470

Neomycin sulfate 30+ Cited Publications	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields	Bacterial Antibiotic Phospholipase
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-W612338

9-Oxononanoic acid 9-ONA	Structural Classification Arachis hypogaea L. Leguminosae Ketones, Aldehydes, Acids Source classification Plants	Phospholipase Prostaglandin Receptor
9-Oxononanoic acid (9-ONA) is secondary reaction product of lipid peroxidation. 9-Oxononanoic acid induces phospholipase A2 (PLA2) activity and thromboxane A2 (HY-113350) production (TXA2). 9-Oxononanoic acid induces the platelet aggregation in human blood. 9-Oxononanoic acid is orally active .

HY-123245

Scalaradial	Structural Classification Animals Terpenoids Sesquiterpenes Source classification	TRP Channel Phospholipase ERK Akt
Scalaradial is an inhibitor for bee venom phospholipase A2 (PLA2) and transient receptor potential melastatin 2 (TRPM2) ion channels, with IC₅₀ of 0.07 and 0.21 μM. Scalaradial regulates the phosphorylation of ERK, by inhibiting secretory PLA2 and Akt. Scalaradial inhibits the PMA (HY-18739)-induced release of Arachidonic acid (HY-109590) in the mouse peritoneal macrophage .

HY-N7327

Ochnaflavone	Source classification Ochna atropurpurea DC. Plants	Phospholipase
Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC₅₀ of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC₅₀ of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases .

Species:	Human (10) Mouse (14) Rat (1)
Tag:	His (23) SUMO (2) Tag Free (1) Myc (3) GST (1) Fc (2)
Source:	HEK293 (13) E. coli Cell-free (1) Sf9 insect cells (2) P. pastoris (2) E. coli (9)

Cat. No.	Compare	Product Name	Species	Source

HY-P701964

	Phospholipase C Protein, Bacillus cereus BC_0670; Phosphatidylcholine cholinephosphohydrolase; phospholipase C	Others	E. coli
	Phospholipase C Protein, Bacillus cereus is the recombinant Phospholipase C protein, expressed by E. coli , with tag free. The total length of Phospholipase C Protein, Bacillus cereus is 283 a.a., .

HY-P72293

	*Group XV phospholipase* A2/Pla2g15, Mouse (His, myc)** Group XV phospholipase A2; 1-O-acylceramide synthase; ACS; LLPL; Lysosomal phospholipase A2	Mouse	E. coli
	Group XV phospholipase A2 (Pla2g15) exhibits dual calcium-dependent phospholipase and O-acyltransferase activities that contribute to glycerophospholipid homeostasis and acyl remodeling in acidic cellular compartments. Group XV phospholipase A2/Pla2g15, Mouse (His, myc) is the recombinant mouse-derived Group XV phospholipase A2/Pla2g15, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of Group XV phospholipase A2/Pla2g15, Mouse (His, myc) is 379 a.a., with molecular weight of ~50.5 kDa.

HY-P71071

	PLA2G1B Protein, Human (HEK293, His) 1 Publications Verification PLA2G1B; phospholipase A2; Group IB phospholipase A2; PLA2; PLA2A; PPLA2	Human	HEK293
	The PLA2G1B protein is a secreted calcium-dependent phospholipase A2 that targets dietary phospholipids in the intestine. It hydrolyzes the fatty acyl group at the sn-2 position, preferentially hydrolyzing phosphatidylethanolamine and phosphatidylglycerol. PLA2G1B Protein, Human (HEK293, His) is the recombinant human-derived PLA2G1B protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PLA2G1B Protein, Human (HEK293, His) is 126 a.a., with molecular weight of 17-20 kDa.

HY-P71212

	PLA2G1B Protein, Mouse (HEK293, His) phospholipase A2; Group IB phospholipase A2; PLA2-Ib; Phosphatidylcholine 2-acylhydrolase 1B; Pla2g1b; Pla2	Mouse	HEK293
	The PLA2G1B protein is a secreted calcium-dependent phospholipase A2 that targets dietary phospholipids in the intestine.Phosphatidylethanolamine and phosphatidylglycerol are preferred, which hydrolyze the ester bond of the fatty acyl group at the sn-2 position.PLA2G1B Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLA2G1B protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71653

	PLA2G2D Protein, Human (His-SUMO) 2IID; EC 3.1.1.4; GIID sPLA2; Group IID secretory phospholipase A2; phospholipase A2 group IID ; Pla2g2d; PLA2IID; stroma-associated homolog	Human	E. coli
	PLA2G2D protein is a secreted calcium-dependent phospholipase A2 that targets extracellular lipids and has anti-inflammatory and immunosuppressive functions.It hydrolyzes the fatty acyl group at the sn-2 position, preferentially hydrolyzing phosphatidylethanolamine and phosphatidylglycerol.PLA2G2D Protein, Human (His-SUMO) is the recombinant human-derived PLA2G2D protein, expressed by E.coli , with N-His, N-SUMO labeled tag.

HY-P701965

	Phospholipase C Protein, Bacillus cereus (His) BC_0670; Phosphatidylcholine cholinephosphohydrolase; phospholipase C	Others	E. coli
	Phospholipase C Protein, Bacillus cereus (His) is the recombinant Phospholipase C protein, expressed by E. coli , with N-6*His labeled tag. The total length of Phospholipase C Protein, Bacillus cereus (His) is 283 a.a., .

HY-P703036

	PLCD4 Protein, Human (sf9, GST) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; hPLCD4; Phosphoinositide phospholipase C-delta-4; phospholipase C-delta-4 (PLC-delta-4)	Human	Sf9 insect cells
	PLCD4 Protein, Human (sf9, GST) is the recombinant human-derived PLCD4, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P700567

	PLA2G7 Protein, Mouse (Baculovirus, N-His, C-Myc) PLA2G7; phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma); platelet-activating factor acetylhydrolase; LDL PLA2; PAFAH; LDL-PLA(2); gVIIA-PLA2; PAF 2-acylhydrolase; PAF acetylhydrolase; group-VIIA phospholipase A2; LDL-associated phospholipase A2; lipoprotein-associated phospholipase A2; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; PAFAD; LP-PLA2; LDL-PLA2	Mouse	Sf9 insect cells
	The PLA2G7 protein is a lipoprotein-associated calcium-independent phospholipase A2 that plays a key role in phospholipid catabolism during inflammation and oxidative stress responses.It acts at the lipid-water interface and hydrolyzes the ester bond of the fatty acyl group at the sn-2 position, with particular preference for short-chain fatty acyl groups.PLA2G7 Protein, Mouse (Baculovirus, N-His, C-Myc) is the recombinant mouse-derived PLA2G7 protein, expressed by Sf9 insect cells , with C-Myc, N-10*His labeled tag.

HY-P700568

	PLA2G7 Protein, Mouse (HEK293, N-His, C-Myc) PLA2G7; phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma); platelet-activating factor acetylhydrolase; LDL PLA2; PAFAH; LDL-PLA(2); gVIIA-PLA2; PAF 2-acylhydrolase; PAF acetylhydrolase; group-VIIA phospholipase A2; LDL-associated phospholipase A2; lipoprotein-associated phospholipase A2; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; PAFAD; LP-PLA2; LDL-PLA2	Mouse	HEK293
	The PLA2G7 protein is a lipoprotein-associated calcium-independent phospholipase A2 that plays a key role in phospholipid catabolism during inflammation and oxidative stress responses.It acts at the lipid-water interface and hydrolyzes the ester bond of the fatty acyl group at the sn-2 position, with particular preference for short-chain fatty acyl groups.PLA2G7 Protein, Mouse (HEK293, N-His, C-Myc) is the recombinant mouse-derived PLA2G7 protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag.

HY-P77144

	PLA2G12B Protein, Mouse (HEK293, His) Group XIIB phospholipase A2-like protein	Mouse	HEK293
	PLA2G12B Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLA2G12B protein, expressed by HEK293 , with C-His labeled tag. The total length of PLA2G12B Protein, Mouse (HEK293, His) is 176 a.a., with molecular weight of ~24 kDa.

HY-P74628

	PLA2G2A Protein, Mouse (P.pastoris, His) 1 Publications Verification phospholipase A2, membrane associated; EF; GIIC sPLA2	Mouse	P. pastoris
	PLA2G2A Protein, a phospholipase A2 enzyme, efficiently hydrolyzes phosphatidylethanolamines and phosphatidylglycerols, contributing to lipid membrane remodeling and generating lipid mediators crucial for pathogen clearance.PLA2G2A Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived PLA2G2A protein, expressed by P.pastoris , with C-His labeled tag.

HY-P75977

	PLA2G2A Protein, Human (HEK293, His) phospholipase A2, membrane associated; EF; GIIC sPLA2	Human	HEK293
	The PLA2G2A protein is a secreted calcium-dependent phospholipase A2 that selectively targets extracellular phospholipids and contributes to host antimicrobial defense, inflammation, and tissue regeneration. It has phospholipase A2 activity, which preferentially hydrolyzes fatty acyl groups, phosphatidylethanolamine and phosphatidylglycerol. PLA2G2A Protein, Human (HEK293, His) is the recombinant human-derived PLA2G2A protein, expressed by HEK293 , with C-His labeled tag.

HY-P77138

	PLA2G2E Protein, Mouse (HEK293, His) Group IIE secretory phospholipase A2; GIIE sPLA2	Mouse	HEK293
	The PLA2G2E protein is a secreted calcium-dependent phospholipase A2 that targets extracellular phospholipids. It hydrolyzes the fatty acyl group at the sn-2 position, releasing unsaturated fatty acids, especially lysophosphatidylethanolamine. PLA2G2E Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLA2G2E protein, expressed by HEK293 , with C-His labeled tag.

HY-P71557

	PLBD2 Protein, Rat (His-SUMO) Plbd2; RDCR-0918-3; Putative phospholipase B-like 2; EC 3.1.1.-; LAMA-like protein 2; Lamina ancestor homolog 2; phospholipase B domain-containing protein 2	Rat	E. coli
	The PLBD2 protein is a putative phospholipase that may participate in cellular processes by interacting with IGF2R. Although the function and mechanism of the enzyme are unclear, its association with IGF2R suggests involvement in the insulin-like growth factor 2 receptor-related signaling pathway. PLBD2 Protein, Rat (His-SUMO) is the recombinant rat-derived PLBD2 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P70993

	PLA2G7 Protein, Human (HEK293, His) Platelet-Activating Factor Acetylhydrolase; PAF Acetylhydrolase; 1-Alkyl-2-Acetylglycerophosphocholine Esterase; 2-Acetyl-1-Alkylglycerophosphocholine Esterase; Group-VIIA phospholipase A2; gVIIA-PLA2; LDL-Associated phospholipase A2; LDL-PLA(2); PAF 2-Acylhydrol	Human	HEK293
	PLA2G7 Protein is a lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress responses. It is also a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. PLA2G7 can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups. PLA2G7 Protein, Human (HEK293, His) is the recombinant human-derived PLA2G7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PLA2G7 Protein, Human (HEK293, His) is 420 a.a., with molecular weight of ~57 kDa.

HY-P76549

	PLA2G2D Protein, Mouse (HEK293, Fc) Group IID secretory phospholipase A2; GIID sPLA2; PLA2IID; Splash	Mouse	HEK293
	PLA2G2D protein is a secreted calcium-dependent phospholipase A2 that targets extracellular lipids and has anti-inflammatory and immunosuppressive functions.It hydrolyzes the fatty acyl group at the sn-2 position, preferentially hydrolyzing phosphatidylethanolamine and phosphatidylglycerol.PLA2G2D Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived PLA2G2D protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77821

	PLD4 Protein, Mouse (HEK293, His) 5'-3' exonuclease PLD4; Choline phosphatase 4; phospholipase D4; PLD 4	Mouse	HEK293
	PLD4 Protein, with 5'->3' DNA exonuclease activity, efficiently digests single-stranded DNA (ssDNA). It crucially regulates inflammatory cytokine responses by degrading nucleic acids, reducing ssDNA concentrations activating TLR9. Additionally, PLD4 actively participates in the phagocytosis process of activated microglia, emphasizing its role in immune responses. PLD4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLD4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78019

	PLD4 Protein, Human (HEK293, His) 5'-3' exonuclease PLD4; Choline phosphatase 4; phospholipase D4; PLD 4	Human	HEK293
	PLD4 Protein, a phospholipase, plays a crucial role in immune responses and inflammation. Dysregulation of PLD4 Protein has been associated with autoimmune disorders and inflammatory diseases. Targeting PLD4 Protein may provide potential therapeutic interventions in these conditions by modulating immune responses, suppressing inflammation, and managing related disorders. PLD4 Protein, Human (HEK293, His) is the recombinant human-derived PLD4 protein, expressed by HEK293 , with C-His labeled tag. The total length of PLD4 Protein, Human (HEK293, His) is 455 a.a., with molecular weight of 68-75 kDa.

HY-P77148

	PLBD2 Protein, Human (HEK293, His) Putative phospholipase B-like 2; p76; LAMA-like protein 2; PLBD2	Human	HEK293
	The PLBD2 protein is a putative phospholipase that interacts with IGF2R, suggesting a potential role in insulin-like growth factor 2 receptor-related signaling pathways. Although the enzymatic activity and functional role of PLBD2 remain to be characterized in detail, its association with IGF2R suggests involvement in cell signaling related to growth and development. PLBD2 Protein, Human (HEK293, His) is the recombinant human-derived PLBD2 protein, expressed by HEK293 , with C-His labeled tag. The total length of PLBD2 Protein, Human (HEK293, His) is 548 a.a., with molecular weight of ~80 & 45 & 32 kDa, respectively.

HY-P78340

	PLA2G1B Protein, Mouse (HEK293, Fc) phospholipase A2; PLA2G1B; PLA2; PLA2A; PLA2AMGC119834	Mouse	HEK293
	The PLA2G1B protein is a secreted calcium-dependent phospholipase A2 that targets dietary phospholipids in the intestine.Phosphatidylethanolamine and phosphatidylglycerol are preferred, which hydrolyze the ester bond of the fatty acyl group at the sn-2 position.PLA2G1B Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived PLA2G1B protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P702447

	SMPD2 Protein, Human (Cell-Free, His) Sphingomyelin phosphodiesterase 2; Lyso-platelet-activating factor-phospholipase C; Lyso-PAF-PLC; Neutral sphingomyelinase; N-SMase; nSMase; nSMase1	Human	E. coli Cell-free
	In vitro experiments have demonstrated that the sphingomyelin phosphodiesterase 2 (SMPD2) protein plays a key role in catalyzing the hydrolysis of sphingomyelin, leading to the formation of ceramide and phosphocholine. Furthermore, SMPD2 exhibits its enzymatic activity by hydrolyzing 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (hemolytic platelet-activating factor) in vivo. SMPD2 Protein, Human (Cell-Free, His) is the recombinant human-derived SMPD2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of SMPD2 Protein, Human (Cell-Free, His) is 423 a.a., with molecular weight of 49.1 kDa.

HY-P71211

	PLA2G16 Protein, Human (His) Group XVI phospholipase A1/A2; Adipose-Specific phospholipase A2; AdPLA; H-Rev 107 Protein Homolog; HRAS-Like Suppressor 1; HRAS-Like Suppressor 3; HRSL3; HREV107-1; HREV107-3; Renal Carcinoma Antigen NY-REN-65; PLA2G16; HRASLS3; HREV107	Human	E. coli
	The PLA2G16 protein has dual functions, acting as a phospholipase to exert calcium-independent PLA1 and PLA2 activities, preferentially releasing fatty acids through PLA1. It also acts as an O-acyltransferase and N-acyltransferase, helping to form N-acylphosphatidylethanolamine (the precursor of N-acylethanolamine). PLA2G16 Protein, Human (His) is the recombinant human-derived PLA2G16 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PLA2G16 Protein, Human (His) is 121 a.a., with molecular weight of 14-17 kDa.

HY-P77444

	PLA2G7 Protein, Mouse (419a.a, HEK293, His) Platelet-Activating Factor Acetylhydrolase; gVIIA-PLA2; LDL-Associated phospholipase A2; LDL-PLA(2); PAF 2-Acylhydrol	Mouse	HEK293
	The PLA2G7 protein is a lipoprotein-associated calcium-independent phospholipase A2 that plays a key role in phospholipid catabolism during inflammation and oxidative stress responses.It acts at the lipid-water interface and hydrolyzes the ester bond of the fatty acyl group at the sn-2 position, with particular preference for short-chain fatty acyl groups.PLA2G7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLA2G7 protein, expressed by HEK293 , with C-His, C-6*His labeled tag.

HY-P72078

	Annexin A1/ANXA1 Protein, Mouse (His) Anxa1; Anx1; Lpc-1; Lpc1Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; phospholipase A2 inhibitory protein; p35	Mouse	E. coli
	Annexin A1 (ANXA1) plays multifaceted roles in innate and adaptive immune responses.It acts as an effector of glucocorticoid-mediated responses, downregulating early inflammation.Annexin A1/ANXA1 Protein, Mouse (His) is the recombinant mouse-derived Annexin A1/ANXA1 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P71553

	PLBD2 Protein, Mouse (His) Plbd2; Putative phospholipase B-like 2; EC 3.1.1.-; 66.3kDa protein; 76kDa protein; p76; LAMA-like protein 2; Lamina ancestor homolog 2	Mouse	E. coli
	PLBD2 Protein, a putative phospholipase, interacts with insulin-like growth factor 2 receptor (IGF2R), suggesting involvement in growth and signaling pathways. Despite unknown details about its phospholipase activity, PLBD2's exploration may unveil insights into its role in cellular homeostasis and regulatory mechanisms. PLBD2 Protein, Mouse (His) is the recombinant mouse-derived PLBD2 protein, expressed by E. coli , with N-His labeled tag.

HY-P71713

	Annexin A1/ANXA1 Protein, Mouse (P.pastoris, His) Anxa1; Anx1; Lpc-1; Lpc1Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; phospholipase A2 inhibitory protein; p35	Mouse	P. pastoris
	Annexin A1 (ANXA1) plays multifaceted roles in innate and adaptive immune responses.It acts as an effector of glucocorticoid-mediated responses, downregulating early inflammation.Annexin A1/ANXA1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Annexin A1/ANXA1 protein, expressed by P.pastoris , with N-His labeled tag.

HY-P71145

	PRDX6 Protein, Human (His) Peroxiredoxin-6; 1-Cys Peroxiredoxin; 1-Cys PRX; 24 kDa Protein; Acidic Calcium-Independent phospholipase A2; aiPLA2; Antioxidant Protein 2; Liver 2D PAGE Spot 40; Non-Selenium Glutathione Peroxidase; NSGPx; Red Blood Cells Page Spot 12; PRDX6; AOP2; KIAA0106	Human	E. coli
	The PRDX6 protein is a thiol-specific peroxidase that plays a crucial role in cellular defense against oxidative stress. It catalyzes the reduction of hydrogen peroxide and various organic hydroperoxides to water and alcohols. PRDX6 Protein, Human (His) is the recombinant human-derived PRDX6 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PRDX6 Protein, Human (His) is 224 a.a., with molecular weight of 30-33 kDa.

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Cat. No.	Product Name	Chemical Structure

HY-W019838S

D-Erythro-dihydrosphingosine-d7
D-Erythro-dihydrosphingosine-d₇ is the deuterium labeled D-Erythro-dihydrosphingosine. D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80427

	Phospholipase C gamma 1 Antibody PLC gamma 1 antibody; PLC II antibody; PLC-148 antibody; PLCgamma1 antibody; PLCG1; NCKAP3	WB, ICC/IF, IP	Human
	Phospholipase C gamma 1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 149 kDa, targeting to Phospholipase C gamma 1. It can be used for WB,ICC,IP assays with tag free, in the background of Human.

HY-P80544

	Annexin A1 Antibody (YA832) ANXA1; ANX1; LPC1; Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; phospholipase A2 inhibitory protein; p35	WB	Human, Mouse, Rat, Monkey
	Annexin A1 Antibody (YA832) is a non-conjugated and Mouse origined monoclonal antibody about 39 kDa, targeting to Annexin A1 (5E4D8). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P82949

	Phospholipase C beta 3 Antibody (YA2694) PLCB3; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase beta-3; Phosphoinositide phospholipase C-beta-3; phospholipase C-beta-3; PLC-beta-3	WB, IHC-P	Human
	Phospholipase C beta 3 Antibody (YA2694) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2694), targeting Phospholipase C beta 3, with a predicted molecular weight of 139 kDa (observed band size: 150 kDa). Phospholipase C beta 3 Antibody (YA2694) can be used for WB, IHC-P experiment in human background.

HY-P83089

	Phospholipase A2 Activator Protein Antibody (YA2834) Glycerophosphatase; PLA2P; Plaa; PLAP	WB, IHC-P, ICC/IF, IP	Human
	Phospholipase A2 Activator Protein Antibody (YA2834) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2834), targeting Phospholipase A2 Activator Protein, with a predicted molecular weight of 87 kDa (observed band size: 75 kDa). Phospholipase A2 Activator Protein Antibody (YA2834) can be used for WB, IHC-P, ICC/IF, IP experiment in human background.

HY-P81881

	Phospholipase C beta 1 Antibody (YA1626) Plcb; AI132408; mKIAA0581; 3110043I21Rik	WB	Rat
	Phospholipase C beta 1 Antibody (YA1626) is a biotin-conjugated non-conjugated IgG antibody, targeting Phospholipase C beta 1, with a predicted molecular weight of 138 kDa (observed band size: 138 kDa). Phospholipase C beta 1 Antibody (YA1626) can be used for WB experiment in rat background.

HY-P82171

	*Secretory Phospholipase* A2 Antibody (YA1916)** MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2	WB	Human, Mouse, Rat
	Secretory Phospholipase A2 Antibody (YA1916) is a biotin-conjugated non-conjugated IgG antibody, targeting Secretory Phospholipase A2, with a predicted molecular weight of 16 kDa (observed band size: 16 kDa). Secretory Phospholipase A2 Antibody (YA1916) can be used for WB experiment in human, mouse, rat background.

HY-P83555

	ERp57 Antibody (YA3300) ERp57; ERp60; ERp61; Glucose Regulated Protein 58 Kd; HsT17083; p58; PDIA3; phospholipase C alpha; PI PLC	WB, IHC-P, IP	Human
	ERp57 Antibody (YA3300) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3300), targeting ERp57, with a predicted molecular weight of 57 kDa (observed band size: 57 kDa). ERp57 Antibody (YA3300) can be used for WB, IHC-P, IP experiment in human background.