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Antifungal agents

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (59) Apoptosis (12) ATP Synthase (1) Autophagy (15) Bacterial (92) Biochemical Assay Reagents (6) Cuproptosis (2) Cytochrome P450 (20) Drug Metabolite (1) Endogenous Metabolite (7) Farnesyl Transferase (1) Ferroptosis (7) Fungal (357) Hedgehog (4) HIV (2) HSP (1) Influenza Virus (1) IPK Superfamily (1) Isotope-Labeled Compounds (10) Lipoxygenase (1) Microtubule/Tubulin (4) Mitochondrial Metabolism (2) Mitophagy (2) MMP (1) mTOR (1) NF-κB (2) Oxidative Phosphorylation (2) p38 MAPK (3) Parasite (16) Phosphatase (1) PPAR (2) Proton Pump (2) Ras (5) Reactive Oxygen Species (2) SARS-CoV (2) Topoisomerase (2) Virus Protease (1) Wnt (1)
By Research Areas:	Cancer (74) Cardiovascular Disease (2) Infection (351) Inflammation/Immunology (30) Metabolic Disease (7) Neurological Disease (5)
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381

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17578

Pneumocandin B0 L-688786	Fungal Antibiotic	Infection
Pneumocandin B0 (L-688786), the precursor of the antifungal agent Caspofungin acetate, is an antifungal agent belonging to the echinocandin family. Pneumocandin B0, derived from the flamentous fungus Glarea lozoyensis, is a synthetic intermediate of Cancidas .

HY-155331

Antifungal agent 77	Fungal	Infection
Antifungal agent 77 (Compound 13h) is an antifungal agent. Antifungal agent 77 (500 μg/mL) also shows good insecticidal activity against Mythimna separate, Helicoverpa armigera, Ostrinia nubilalis, and Spodoptera frugiperda with a death rate of 30%, 25%, 40%, and 25%. Antifungal agent 77 shows toxicity in zebrafish embryo with a LC₅₀ of 2.43 μg/mL .

HY-149603

Antifungal agent 78	Fungal	Infection
Antifungal agent 78 (compound 25am) is an antifungal agent with an EC₅₀ value of 13.46 μM against F. graminearum .

HY-156252

Antifungal agent 75	Fungal	Infection
Antifungal agent 75 (compound 6r) is a potent antifungal agent against Candida albicans. Antifungal agent 75 significantly inhibits the formation of C. albicans biofilm, increases the permeability of the cell membrane, reduces the ergosterol level of the cell membrane, damages the membrane structure, and destroys the integrity of the cell structure to exert excellent antifungal activity .

HY-163781

Antifungal agent 105	Fungal	Infection
Antifungal agent 105 (compound A25) is a potent antifungal agent. Antifungal agent 105 shows protective and curative effects .

HY-N10101

Eriobofuran	Fungal	Infection
Eriobofuran is an antifungal agent can be isolated from Sorbus aucuparia .

HY-147970

Antifungal agent 34	Fungal	Infection
Antifungal agent 34 (compound 6i) is a potent *antifungal* agent. Antifungal agent 34 shows a potent antifungal activity against Candida albicans, with a MIC of 4 µg/mL. Antifungal agent 34 shows significant inhibition on Candida albicans hyphae and biofilm development. Antifungal agent 34 exhibits no cytotoxicity to mammalian cells .

HY-156251

Antifungal agent 74	Fungal	Infection
Antifungal agent 74 (compound 3c) is a potent antifungal agent that displays excellent fungicidal activity against C. arachidicola and R. solani. Antifungal agent 74 exerts its fungicidal activity by disrupting steroid biosynthesis and ribosome biogenesis in eukaryotes .

HY-N3089

Phaseollidin	Fungal	Others
Phaseollidin is an *antifungal* agent that can be isolated from Phaseolus vulgaris L. .

HY-146079

Antifungal agent 31	Fungal	Infection
Antifungal agent 31 (compound 12) is a potent and orally active triazole antifungal agents with a pyrrolotriazinone scaffold. Antifungal agent 31 shows antifungal activity against Candida spp. and filamentous fungi. Antifungal agent 31 significantly reduced mortality rates and kidney fungal burden in two murine models of lethal systemic infections .

HY-16719

Dapaconazole	Cytochrome P450	Infection
Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC₅₀ of 1.4 μM .

HY-B0263S

Thiabendazole-d4 2-(4-Thiazolyl)benzimidazole-d₄	Mitochondrial Metabolism Parasite	Others
Thiabendazole-d₄ is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].

HY-17011

Croconazole	Others	Metabolic Disease
Croconazole is an *antifungal* agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile .

HY-N3041

Plumieride Agoniadin; NSC 609065	Fungal	Infection Cancer
Plumieride is an *antifungal* agent. Plumieride has strong fungitoxicity against some dermatophytes. Plumieride has little cytotoxic activity against the P388 leukaemia cell line with an IC₅₀ of 85 μg/mL .

HY-P2460

SMAP-29	Bacterial Fungal	Infection Inflammation/Immunology
SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism .

HY-B0101

Fluconazole 10+ Cited Publications UK-49858	Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (UK-49858) is a triazole *antifungal* agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

HY-B0101R

Fluconazole (Standard)	Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .

HY-169165

14α-Demethylase-IN-1	Fungal	Infection
14α-Demethylase-IN-1 (compound 2e) is a 14α-demethylase inhibitor and can be used as an antifungal agent. 14α-Demethylase-IN-1 (48 h) exhibits MIC50 values of 2.47 μM, 1.23 μM, 19.70 μM, and 19.70 μM for C. albicans, C. parapsilosis, C. krusei, and C. glabrata, respectively .

HY-148054

Antifungal agent 36	Fungal	Infection
Antifungal agent 36 is a potent *anti-fungal* agent. Antifungal agent 36 shows anti-fungal activity for Basidiomycetes .

HY-151442

Antifungal agent 43	Fungal	Infection
Antifungal agent 43 (compound B05) is an antifungal agent. Antifungal agents 43 has antifungal activity by inhibiting biofilm formation. Antifungal agent 43 has low toxicity in human cancer cell lines .

HY-138576

Antifungal agent 6	Fungal	Infection
Antifungal agent 6 is an antifungal agent.

HY-147238

Antifungal agent 35	Fungal	Infection
Antifungal agent 35 (compound 24) is a potent antifungal agent. Antifungal agent 35 is a potent enhancer of antifungal activity of Fluconazole against C. albicans .

HY-143406

Antifungal agent 25	Fungal	Infection
Antifungal agent 25 is a potent broad-spectrum antifungal agent. Antifungal agent 25 shows antifungal effect against Candida albicans and fluconazole-resistant strain of Candida albicans. Antifungal agent 25 stable metabolic property in vivo .

HY-161312

Antifungal agent 93	Bacterial Fungal	Infection
Antifungal agent 93 (compound 10) is a potent antifungal agent. Antifungal agent 93 shows antimicrobial activity .

HY-102025

Antifungal agent 1	Fungal	Infection
Antifungal agent 1 is a potent *antifungal* agent.

HY-W012192

trans,trans-Dibenzylideneacetone (E,E)-Dibenzylideneacetone; trans,trans-Dibenzalacetone	Fungal	Infection
Dibenzylideneacetone (DBA) is a fruit antifungal agent with inhibitory activity against Botrytis cinerea Chitinase with an IC₅₀ of 13.10 μg/mL. Dibenzylideneacetone has an MIC of 32 μg/mL against B. cinerea and EC₅₀ values of 16.29 and 14.64 μg/mL in inhibiting mycelial growth and spore germination, respectively. Dibenzylideneacetone can overcomes Botrytis cinerea infection in cherry tomatoes by inhibiting chitinase activity .

HY-151440

Antifungal agent 42	Fungal	Infection
Antifungal agent 42 is an antifungal agent. Antifungal agent 42 has an inhibitory effect on lanosterol 14α-demethylase (CYP51) of C.alb.. Antifungal agent 42 inhibits biofilm formation .

HY-151439

Antifungal agent 41	Fungal	Infection
Antifungal agent 41 (compound B01) is an **antifungal agent*. Antifungal* agent 41 shows inhibitory effect on Candida albicans in virto and vivo. Antifungal agent 41 can be used for the research of invasive fungal infections .

HY-146464

Antifungal agent 30	Fungal	Infection
Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51 .

HY-146024

Antifungal agent 28	Fungal	Infection
Antifungal agent 28 (compound 18) is a potent and selective antifungal agent. Antifungal agent 28 inhibits pathogenic strains of C. albicans and non-albicans species including fluconazole-resistant strains. Antifungal agent 28 inhibits Cryptococcus and Aspergillus strains. Antifungal agent 28 disrupts mature Candida biofilm .

HY-146116

Antifungal agent 32	Fungal	Infection
Antifungal agent 32 (compound 1a) is a potent antifungal agent. Antifungal agent 32 inhibits Candida albicans filamentation and biofilm formation. Antifungal agent 32 inhibits the morphological switching of Candida albicans and its adherence to epithelial cells. Antifungal agent 32 can be used for Candida albicans infections research .

HY-155279

Antifungal agent 73	Fungal	Infection
Antifungal agent 73 (compound A32) is an *antifungal* agent for azole-resistant candidiasis. Antifungal agent 73 disrupts the fungal cell wall and cell membrane. Antifungal agent 73 shows potent in vivo antifungal activity against pathogenic fungi and fluconazole-resistant strains .

HY-153409

Antifungal agent 48	Fungal	Infection
Antifungal agent 48 (Example 308) is an antifungal agent. Antifungal agent 48 is active against Cryptococcus neoformans with a MIC value of 11 μM .

HY-153410

Antifungal agent 49	Fungal	Infection
Antifungal agent 49 (Example 112) is an antifungal agent. Antifungal agent 49 is active against Cryptococcus neoformans with a MIC value of 49 μM .

HY-151566

Antifungal agent 46	Ras Farnesyl Transferase Fungal	Infection
Antifungal agent 46 (compound 2f) is a potent antifungal agent. Antifungal agent 46 prevents Ras signaling by inhibiting protein farnesyltransferase .

HY-146427

Antifungal agent 29	Fungal	Infection
Antifungal agent 29 (compound 9d) is a potent, selective and non-toxic antifungal agent. Antifungal agent 29 shows antifungal activity towards Cryptococcus neoformans (MIC ≤ 0.23 μM) .

HY-158980

Antifungal agent 103	Fungal Bacterial	Infection
Antifungal agent 103 (compound 7y) is a potent *antifungal* agent. Antifungal agent 103 inhibits R. solani with an EC₅₀ of 0.47 μg/mL .

HY-157018

Antifungal agent 82	Fungal	Infection
Antifungal agent 82 (compound G34) is a *antifungal* agent. Antifungal agent 82 exhibits excellent in vitro antifungal activity against Valsa mali, with an EC₅₀ of 0.57 μg/mL. Antifungal agent 82 also exhibits excellent in vivo protective effects against V. mali at 40 μg/mL .

HY-139903

Antifungal agent 18	Fungal	Infection
Antifungal agent 18 is a novel antifungal agent for the research of fungal infection.

HY-143335

Antifungal agent 52	Fungal	Infection
Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization .

HY-153618

Antifungal agent 53	Fungal	Infection
Antifungal agent 53 (A03) is a potent inhibitor of Candida albicans CYP51 with antifungal activity. Antifungal agent 53 prevents the formation of fungi biofilms. Antifungal agent 53 also exhibits good safety .

HY-142914

Antifungal agent 21	Fungal	Others
Antifungal agent 21 is a promising candidate in the development of new agrochemical antifungal agents.

HY-153624

Antifungal agent 59	Fungal	Infection
Antifungal agent 59 is an antifungal agent, with MIC values of 0.01-1 μg/mL. Antifungal agent 59 prevents the formation of fungi biofilms, but also has safety .

HY-146023

Antifungal agent 27	Bacterial Fungal	Infection
Antifungal agent 27 (compound 7) is a antifungal agent. Antifungal agent 27 shows moderate antibacterial and weak antifungal activities against MRSA and C. albicans SS5314, with MIC values of 8 and 32 μg/mL, respectively .

HY-147919

Antifungal agent 33	Fungal	Infection
Antifungal agent 33 (compound 4e) is a potent *antifungal* agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC₅₀ of 0.19 μg/mL .

HY-151437

Antifungal agent 40	Fungal	Infection
Antifungal agent 40 is an antifungal agent which extends into the narrow hydrophobic pocket II of C.alb. CYP51. Antifungal agent 40 has an inhibitory effect on lanosterol 14α-demethylase (CYP51). Antifungal agent 40 inhibits biofilm formation .

HY-151423

Antifungal agent 39	Fungal	Infection
Antifungal agent 39 (Compound 9h) is a broad-spectrum *antifungal* agent .

HY-151284

Antifungal agent 38	Bacterial Fungal	Infection
Antifungal agent 38 is a geterocyclic disulfide, an antifungal and antibacterial agent. Antifungal agent 38 induces the shrinkage of hyphae, disrupts the integrity of the plasma membrane, and causes the damage and leakage of cell contents .

HY-164643

Antifungal agent 113	Antibiotic Fungal	Infection
Antifungal agent 113 (compound 9a) is a potent *antifungal* and antibacterial agent. Antifungal agent 113 shows good antibacterial activity against S. aureus and methicillin-resistant S. aureus .

HY-155702

Antifungal agent 66	Fungal	Infection
Antifungal agent 66 (compound 10) has antifungal activity. Antifungal agent 66 has a broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia. Antifungal agent 66 has pronounced inhibitory activity against the spore of B. cinerea with an IC₅₀ value of 47.7 μg/mL .

Cat. No.	Product Name

HY-L048

Antifungal Compound Library

386 compounds

The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is challenging because there are many similarities between fungal and human cells. The most common antifungal targets include fungal RNA synthesis and cell wall and membrane components, though new antifungal targets are being investigated. Nonetheless, fungi have developed resistance mechanisms, such as overexpression of efflux pump proteins, overexpression and changes in drug targets and biofilm formation, emphasizing the importance of discovering new antifungal drugs and therapies. Due to the limited antifungal arsenal, researchers have sought to improve treatment via different approaches, such as the combination of antifungal drugs, development of new formulations for antifungal agents and modifications to the chemical structures of traditional antifungals, etc.

MCE offers a unique collection of 386 compounds with validated antifungal activities. MCE antifungal compound library is an effective tool for drug repurposing screening, combination screening and biological investigation.

HY-L002

Anti-Infection Compound Library

3,100 compounds

An infection occurs when another organism enters a person’s body and causes disease. The organisms that cause infections are very diverse and can include things like viruses, bacteria, fungi, and parasites. The immune system is an effective barrier against infectious agents.

MCE provides a unique collection of 3,100 anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities that can be used for drug screening and other research in anti-microbial area.

Cat. No.	Product Name	Type

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Fluorescent Dye

Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

Cat. No.	Product Name	Type

HY-119976

Boscalid	Microbial Culture
Boscalid is an *anti-fungal* agent. Boscalid is a succinate dehydrogenase (SDH) inhibitor .

HY-W127452

Undecylenate sodium

1 Publications Verification

Drug Delivery

Undecylenate SodiumIt is an organic compound belonging to the class of carboxylates. It is formed by the reaction of undecylenic acid and sodium hydroxide. Undecylenate SodiumIt has a variety of applications in the cosmetic and personal care industries, especially as an antifungal agent in products such as face creams, lotions and shampoos. In addition, it can be used as a preservative in various formulations.

HY-138540

1-Dodecylimidazole 1 Publications Verification N-Dodecylimidazole	Cell Assay Reagents
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity .

HY-W016806

Sodium methylparaben, 99% Sodium methyl 4-hydroxybenzoate, 99%	Surfactants
Sodium methylparaben, 99% (Sodium methyl 4-hydroxybenzoate, 99%) is an antifungal agent .

HY-159104

Cinnamon bark oil, from Cinnamonum zeylanicum Blume Cinnamomum Cassia oil	Co-solvents
Cinnamon bark oil, from Cinnamonum zeylanicum Blume is a antifungal agent against fungi causing respiratory tract mycoses .

HY-106333

Irtemazole R 60844	Biochemical Assay Reagents
Irtemazole is an orally active antifungal agent. Irtemazole possesses uricosuric effect. Irtemazole is used in the research for blastomycosis, histoplasmosis, and aspergillosis .

HY-119976R

Boscalid (Standard)	Microbial Culture
Boscalid (Standard) is the analytical standard of Boscalid. This product is intended for research and analytical applications. Boscalid is an anti-fungal agent. Boscalid is a succinate dehydrogenase (SDH) inhibitor .

HY-W016806R

Sodium methylparaben, 99% (Standard)	Surfactants
Sodium methylparaben, 99% (Standard) is the analytical standard of Sodium methylparaben, 99%. This product is intended for research and analytical applications. Sodium methylparaben, 99% (Sodium methyl 4-hydroxybenzoate, 99%) is an antifungal agent .

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Biochemical Assay Reagents

HY-W010532

trans-3-Hexenoic acid

(E)-Hex-3-enoic acid

Biochemical Assay Reagents

(E)-Hex-3-enoic acid is an unsaturated organic compound. It is commonly used as a fragrance ingredient in a variety of products, including food, beverages, and personal care products, and it can also be used as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, (E)-Hex- 3-enoic acid has been investigated for its potential use as a biobased solvent due to its low toxicity and biodegradability, as well as its potential antibacterial and antifungal properties, which may make it useful for developing new Antibacterial agents.

HY-P2232

Conalbumin

Ovotransferrin

Native Proteins

Conalbumin (Ovotransferrin), also known as ovotransferrin, is a monomeric glycoprotein consisting of 686 amino acids, encoded by the avian transferrin gene in the oviduct, and a prominent component of chicken egg white. Exhibiting a unique glycosylation pattern that differentiates it from serum transferrin, Conalbumin is a potent iron binder that plays a crucial role in iron transport to developing embryos. Additionally, it possesses a range of biological activities, including antimicrobial, antifungal, antiviral, anticancer, antioxidative, antihypertensive, and immunoregulatory properties, making it valuable in numerous applications such as infant formula ingredients, food additives, and agents for enhancing animal health.

HY-W027592

1H-1,2,4-Triazol-3-amine

Cell Assay Reagents

1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.

HY-W027592R

1H-1,2,4-Triazol-3-amine (Standard)

Cell Assay Reagents

1H-1,2,4-Triazol-3-amine (Standard) is the analytical standard of 1H-1,2,4-Triazol-3-amine. This product is intended for research and analytical applications. 1H-1,2,4-Triazol-3-amine consists of a triazole ring system and an amino group attached to carbon atom 3. The compound has potential applications in various fields such as medicinal chemistry, agrochemicals and material science. In medicinal chemistry, 1H-1,2,4-Triazol-3-amine is used as a starting material for the synthesis of pharmaceutical compounds such as antifungal agents, anticancer agents, and enzyme inhibitors associated with cardiovascular disease. In agrochemicals, it can be used as a raw material for the synthesis of herbicides, fungicides and insecticides. Furthermore, 1H-1,2,4-Triazol-3-amine is used as a ligand in coordination chemistry and as a precursor for the production of new functional materials such as polymers and metal-organic frameworks.

Cat. No.	Product Name	Target	Research Area

HY-P2460

SMAP-29	Bacterial Fungal	Infection Inflammation/Immunology
SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism .

HY-P0068

Aminocandin HMR 3270; IP960; NXL201	Fungal	Infection
Aminocandin (HMR 3270) is water-soluble *antifungal* agent of the echinocandin class with excellent activity against Aspergillus and Candida spp. .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-17578

Pneumocandin B0 L-688786	Infection Alkaloids Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Source classification Endogenous metabolite Disease Research Fields	Fungal Antibiotic
Pneumocandin B0 (L-688786), the precursor of the antifungal agent Caspofungin acetate, is an antifungal agent belonging to the echinocandin family. Pneumocandin B0, derived from the flamentous fungus Glarea lozoyensis, is a synthetic intermediate of Cancidas .

HY-B0101

Fluconazole 10+ Cited Publications UK-49858	Microorganisms Source classification	Fungal Antibiotic Bacterial
Fluconazole (UK-49858) is a triazole *antifungal* agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

HY-137794

Tetramethylkaempferol	Structural Classification Flavonoids Flavones Source classification Kaempferia parviflora Wall. ex Baker Plants Zingiberaceae	Fungal
Tetramethylkaempferol is an antifungal agent. Tetramethylkaempferol shows antifungal activity against Candida albicansCandida albicans with an IC₅₀ value of 17.63 µg/mL .

HY-N10101

Eriobofuran	Structural Classification Monophenols Source classification Rosaceae Phenols Plants Sorbus aucuparia Poir.	Fungal
Eriobofuran is an antifungal agent can be isolated from Sorbus aucuparia .

HY-N3089

Phaseollidin	Structural Classification Leguminosae Source classification Phenols Polyphenols Plants Phaseolus vulgaris Linn.	Fungal
Phaseollidin is an *antifungal* agent that can be isolated from Phaseolus vulgaris L. .

HY-N3041

Plumieride Agoniadin; NSC 609065	Apocynaceae Structural Classification Natural Products Source classification Plumeria alba L. Plants	Fungal
Plumieride is an *antifungal* agent. Plumieride has strong fungitoxicity against some dermatophytes. Plumieride has little cytotoxic activity against the P388 leukaemia cell line with an IC₅₀ of 85 μg/mL .

HY-B0101R

Fluconazole (Standard)	Microorganisms Source classification	Fungal Antibiotic Bacterial
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .

HY-N12621

Antifungal agent 91	Structural Classification Flavanonols Flavonoids Artocarpus elasticus Reinw. ex Blume Source classification Plants Moraceae	Phosphatase
Antifungal agent 91(compound 1) is a dihydroflavonol that can be isolated from the leaves of Artocarpus elasticus. Antifungal agent 91 is a PTP1B inhibitor with an IC₅₀ value of 0.17 μM. Antifungal agent 91 has antifungal activity .

HY-N0957

(±)-Pinoresinol	Structural Classification Source classification Melia azedarach L. Phenols Polyphenols Plants Meliaceae	Fungal
(±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity .

HY-125124

Chamaejasmenin D	Structural Classification Flavonoids Thymelaeaceae Source classification Stellera chamaejasme Linn. Plants Biflavones	Fungal
Chamaejasmenin D is an antimitotic and *antifungal* agent .

HY-N9378

3-Oxobetulin	Infection Structural Classification other families Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Plants Disease Research Fields Other Antibiotics	Fungal
3-Oxobetulin, an *antifungal* agent, shows antifungal activities against white rot fungus L. betulina and the brown rot fungus L. sulphureus .

HY-N0954

(+)-Pinoresinol diacetate	Structural Classification other families Ketones, Aldehydes, Acids Source classification Adiantum capillus-veneris L. Plants	Fungal
(+)-Pinoresinol diacetate is an antifungal agent that can be isolated from Sambucus williamsii .

HY-126610

Dactylfungin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Dactylfungin A, an α-pyrone-containing antifungal agent found in Dactylaria parvispora.

HY-N4203

Isopropyl ferulate	Infection Structural Classification Monophenols Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Umbelliferae Kleinia odora (Forssk.) DC. Disease Research Fields	Fungal
Isopropyl ferulate, isolated from Notopterygium incisum, is used in the reduction of pharmaceuticals, preparation of antifungal agents, cosmetics and as antioxidant agent and so forth .

HY-W505771

Seselin	Structural Classification Flavonoids Source classification Ficus erecta Thunb. var. beecheyana (Hook.et Arn.) King Plants Moraceae Other Flavonoids	Fungal
Seselin is an anticancer, antinociceptive, anti-inflammatory and antifungal agent. Seselin is orally active .

HY-117496

Ampelopsin A	Structural Classification Polygonaceae Source classification Phenols Polyphenols Fallopia multiflora (Thunb.) Harald. Plants	Fungal
Ampelopsin A is a antifungal agent and can be isolated from the Vitis vinifera canes. Ampelopsin A shows neuroprotective effects .

HY-103027

Polyoxin B 5-(2-amino-5-O-carbamoyl-2-deoxy-L-xylonamido-1,5-dideoxy-1-(3,4-dihydro-5-hydroxymethyl-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-allofuranuronic acid	Classification of Application Fields Inflammation/Immunology Disease Research Fields	Fungal
Polyoxin B is a potent chitin synthase inhibitor (IC₅₀=0.08 mM) and an effective antifungal agent .

HY-106681

Lagosin Fungichromin; Pentamycin; Cogomycin	Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields Cancer	Antibiotic Fungal
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .

HY-N12023

Deacetylnomilin	Triterpenes Structural Classification Natural Products Terpenoids Source classification Rutaceae Plants Citrus reticulata Blanco	Bacterial Fungal
Deacetylnomilin can be isolated from Citrus reticulata and has antibacterial and antifungal activity. Deacetylnomilin is a potent inhibitor of cell proliferation with an IC₅₀ value of 0.005 ug/mL against estrogen receptor-positive (ER+) cells .

HY-121388

Ledol (+)-Ledol	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Ericaceae Rhododendron tomentosum Harmaja	Fungal
Ledol ((+)-Ledol) is an *antifungal* agent that can be isolated from the essential oil fractions of Rhododendron tomentosum. Ledol is also the expectorant and antitussive agent, which is simultaneously responsible for adverse reactions such as dizziness, nausea and vomiting .

HY-76200

Voriconazole 5+ Cited Publications UK-109496	Microorganisms Source classification	Fungal Bacterial
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole *antifungal* agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .

HY-12538

Graveoline Rutamine	Structural Classification Alkaloids Source classification Ruta graveolens Linn. Rutaceae Quinoline Alkaloids Plants	Apoptosis Autophagy Fungal
Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity .

HY-N12805

α-Cadinol	Structural Classification Terpenoids Sesquiterpenes Source classification Taxodiaceae Plants Cunninghamia lanceolata var. konishii	Fungal Parasite
α-Cadinol is an antifungal agent that can inhibit the growth of Coriolus versicolor and Laetiporus sulfureus.α-Cadinol also possesses antimite activity .

HY-N0709

Coumarin	Infection Structural Classification Microorganisms Classification of Application Fields Ambrosia psilostachya DC. Source classification Coumarins Phenylpropanoids Umbelliferae Plants Inflammation/Immunology Disease Research Fields	Bacterial Fungal
Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity .

HY-129155

(Rac)-Germacrene D	Bursera copallifera (Moc. & Sessé ex DC.) Bullock Source classification Plants Burseraceae	Others
(Rac)-Germacrene D is a racemate of Germacrene D. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles .

HY-N12118

Piperanine	Structural Classification Natural Products Source classification Piperaceae Plants Piper retrofractum Vahl	Fungal
Piperanine is an antifungal agent. Piperanine shows growth inhibition against the fungus Cladosporium claspoirioides. Piperanine can be isolated from the fruits of Piper retrofractum .

HY-B0221

Amphotericin B 10+ Cited Publications	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Antibiotic Bacterial Parasite
Amphotericin B is a polyene antifungal agent against a wide variety of *fungal* pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.

HY-125685

Germacrene D	Classification of Application Fields Vigna mungo (L.) Hepper Plants Compositae Disease Research Fields Cancer	Bacterial Fungal
Germacrene D is isolated from Solidago canadensis. Germacrene D has antibacterial and *antifungal* activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles .

HY-19584

Variotin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .

HY-B0238

Amorolfine hydrochloride Ro 14-4767/002	Infection Classification of Application Fields Disease Research Fields	Fungal Antibiotic
Amorolfine (Ro 14-4767/002) hydrochloride is a potent *anti-fungal* agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis .

HY-N12654

Irumamycin	Structural Classification Microorganisms Antibiotics Source classification	Fungal Parasite Antibiotic
Irumamycin is a natural 20-membered macrolide antibiotic. Irumamycin is active in vitro against some phytopathogenic fungi . Irumamycin also shows potent antitrypanosomal activity .

HY-76200R

Voriconazole (Standard) UK-109496 (Standard)	Microorganisms Source classification	Fungal Bacterial
Voriconazole (Standard) is the analytical standard of Voriconazole. This product is intended for research and analytical applications. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole *antifungal* agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .

HY-B0133

Natamycin 5+ Cited Publications Pimaricin	Structural Classification Preservatives Anti-inflammation/Immunoregulatory Antifungal Classification of Application Fields Source classification Disease Research Endogenous metabolite Food Research Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Fields	Fungal Endogenous Metabolite Antibiotic Bacterial
Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-N10418

Isorhapontin	Pinaceae Source classification Phenols Polyphenols Picea asperata Mast. Plants	Fungal
Isorhapontin is an *antifungal* agent. Isorhapontin inhibits the hydrolytic activity of Trichoderma cellobiohydrolase I (CBH I) with a K_i of 57.2 μM. Isorhapontin also inhibits the activity of Trichoderma endoglucanase I .

HY-111664

(R)-(+)-Citronellal (+)-Citronellal	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Citrus limon (L.) Burm. F. Source classification Rutaceae Metabolic Disease Plants Endogenous metabolite Disease Research Fields Citrus reticulata Blanco	Endogenous Metabolite
(R)-(+)-Citronellal, isolated from citrus, lavender and eucalyptus oils, is a monoterpenoid and main component of citronellal oil with a distinct lemon scent. A flavouring agent. Used for insect repellent and antifungal properties .

HY-111067

(4S)-(+)-Ascochin	Structural Classification Microorganisms Source classification Phenols Polyphenols	Fungal
(4S)-(+)-Ascochin is an antifungal agent against Microbotryum violaceum, Phytophthora infestans and Septoria tritici. (4S)-(+)-Ascochin also exhibits antialgal activity against Chlorella fusca .

HY-N12913

Antibiotic WB	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Fungal
Antibiotic WB is an antibioticwith antifungal activity and can be isolated from the soil fungus strain 38 .

HY-N12808

(E)-4-Methyl-5-styrylbenzene-1,3-diol	Structural Classification Source classification Phenols Polyphenols Plants Asparagaceae Juss.	Fungal
(E)-4-Methyl-5-styrylbenzene-1,3-diol (Compound III) is an *antifungal* agent and can be extracted from Dracaena cochinchinensis (Lour.) S. C. Chen .

HY-N7701

L-Diguluronic acid	Infection Structural Classification Polysaccharides other families Classification of Application Fields Source classification Plants Disease Research Fields Saccharides	Fungal
L-Diguluronic acid is a linear polysaccharide?copolymer composed of two L-guluronic acid (G) and can be used to from Alginate . Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of *antifungal* agents delivery carries .

HY-100711A

Prodigiosin hydrochloride 1 Publications Verification Prodigiosine hydrochloride	Infection Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Pigments Inflammation/Immunology Disease Research Fields Food Research	Bacterial Apoptosis Fungal Wnt Parasite
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .

HY-N0709R

Coumarin (Standard)	Structural Classification Microorganisms Ambrosia psilostachya DC. Source classification Coumarins Phenylpropanoids Umbelliferae Plants	Bacterial Fungal
Coumarin (Standard) is the analytical standard of Coumarin. This product is intended for research and analytical applications. Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity .

HY-N11772

Mutanocyclin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse .

HY-N8329

AS-2077715	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal Antibiotic
AS-2077715 is an antifungal agent that shows inhibitory activity against the Trichophyton species. AS-2077715 can be obtained from the fermentation broth of Capnodium sp. 339855. AS-2077715 can be used to study fungal infections .

HY-N10482

Tinophyllol	Terpenoids Source classification Diterpenoids Plants Menispermaceae Arcangelisia flava (L.) Merr.	Fungal
Tinophyllol, a furanoditerpenoid, is a natural product found in Arcangelisia flava MERR. Tinophyllol has good activity against Botrytis cinerea .

HY-N7133

Diphenylamine hydrochloride N-Phenylaniline hydrochloride	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Amberboa moschata (L.) DC. Umbelliferae Plants Disease Research Fields	Fungal Bacterial
Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and a common structure in non-steroidal anti-inflammatory drugs (NSAIDs) that uncouples oxidative phosphorylation in mitochondria, leading to a decrease in hepatic cell ATP levels and causing liver cell damage. Diphenylamine hydrochloride is also an industrial antioxidant, a dyeing mordant, and is used in agriculture as an antifungal and antibacterial agent .

HY-B0133R

Natamycin (Standard)	Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Antifungal Macrolide Antibiotics Antibiotics Source classification Disease Research Endogenous metabolite	Fungal Endogenous Metabolite Antibiotic Bacterial
Natamycin (Standard) is the analytical standard of Natamycin. This product is intended for research and analytical applications. Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-B0221R

Amphotericin B (Standard)	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Antibiotic Bacterial Parasite
Amphotericin B (Standard) is the analytical standard of Amphotericin B. This product is intended for research and analytical applications. Amphotericin B is a polyene antifungal agent against a wide variety of *fungal* pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.

HY-106784

Ajoene	Infection Natural Products Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel	Fungal Apoptosis
Ajoene, a garlic-derived compound, is an antithrombotic and *antifungal* agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .

HY-N11911

Verazine (-)-Verazine	Structural Classification Alkaloids Other Alkaloids Source classification Veratrum maackii Regel Plants Melanthiaceae	Fungal
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases .

HY-N12164

Linearmycin B	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial Fungal
Linearmycin B is an antibacterial and antifungal agent. Linearmycin B shows activity against Bacillus subtilis (Bs), Staphylococcus aureus (Sa). Candida albicans (Ca), and Saccharomyces cerevisiae (Sc), with MIC values of 0.097, 1.5, 0.0008, and 0.0002 μg/mL, respectively .

Cat. No.	Product Name	Chemical Structure

HY-B0263S

Thiabendazole-d4
Thiabendazole-d₄ is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].

HY-12772S

Hydroxy Itraconazole-d8
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-B0105S1

Ketoconazole-d4
Ketoconazole-d₄ is the deuterium labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.

HY-B0105S

Ketoconazole-d8
Ketoconazole-d₈ is the deuterium labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.

HY-76200S

Voriconazole-d3
Voriconazole-d₃ is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].

HY-B0370S

Tolnaftate (D7)
Tolnaftate-d₇ is the deuterium labeled Tolnaftate. Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent[1][2].

HY-17583S

Griseofulvin-d3
Griseofulvin-d₃ is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal agent[1][2].

HY-B0454S

Miconazole-d5
Miconazole-d₅ is the deuterium labeled Miconazole. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects[2].

HY-B0454S1

Miconazole-d5 nitrate
Miconazole-d₅ (nitrate) is the deuterium labeled Miconazole. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects[2].

HY-B0454S2

Miconazole-d2
Miconazole-d₂ is the deuterium labeled Miconazole[1]. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects[2][3].

HY-B1119S

Triclosan-d3
Triclosan-d₃ is the deuterium labeled Triclosan. Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments[1][2].

HY-B1151S

Climbazole-d4
Climbazole-d₄ is the deuterium labeled Climbazole. Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].

HY-B0454AS

Miconazole-d5 nitrate (2,4-Dichlorobenzyloxy-d5)
Miconazole-d₅ (nitrate) (2,4-Dichlorobenzyloxy-d5) is the deuterium labeled Miconazole nitrate. Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent. Miconazole nitrate also has antibacterial effects[2].

HY-17006S

Caspofungin-d4 diacetate
Caspofungin-d₄ (acetate) is the deuterium labeled Caspofungin diacetate[1]. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[2][3].

HY-B0221S

Amphotericin B-13C6
Amphotericin B- ¹³C₆ is ¹³C labeled Amphotericin B (HY-B0221). Amphotericin B is a polyene antifungal agent against a wide variety of *fungal* pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.

HY-W015551S

trans-2-Decenal-d2
trans-2-Decenal-d₂ is deuterated labeled Coumarin (HY-N0709). Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity .

HY-23155S

2-Phenylethyl isothiocyanate-d5

2-Phenylethyl isothiocyanate-d₅ isothiocyanate-d₅ is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].

HY-B0450S

Ciclopirox-d11
Ciclopirox-d₁₁ is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

HY-B0450S1

Ciclopirox-d11 sodium
Ciclopirox-d₁₁ (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

HY-B0101S

Fluconazole-d4
Fluconazole-d₄ is the deuterium labeled Fluconazole. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL[1].

HY-17006AS

Caspofungin-d4
Caspofungin-d₄ (MK-0991-d₄; L-743872-d₄) is a deuterium labeled Caspofungin (HY-17006A). Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-15660S

Efinaconazole-d4
Efinaconazole-d₄ is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].

HY-17514S

Itraconazole-d5

Itraconazole-d₅ is the deuterium labeled Itraconazole. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects[1][2][3].

HY-114518S2

Butenafine-d4

Butenafine-d4 (KP363-d4) is the deuterium labeled Butenafine (HY-114518). Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as ?tinea pedis, ?tinea cruris, tinea versicolor .

HY-17514S2

Itraconazole-d9

Itraconazole-d₉ is the deuterium labeled Itraconazole[1]. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor[2][3][4][5].

HY-B0101S1

Fluconazole-13C2,15N
Fluconazole-13C2,15N (UK-49858-13C2,15N) is the ¹³C and ¹⁵N labeled isotope of Fluconazole (HY-B0101). Fluconazole (UK-49858) is a triazole *antifungal* agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

Cat. No.	Product Name		Classification

HY-148921

SDH-IN-2		Alkynes
SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 0.55 μg/mL. SDH-IN-2 is also an antifungal agent. SDH-IN-2 inhibits phytopathogenic fungia with average EC₅₀ values of 3.82-9.81 μg/mL for all the fungi . SDH-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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