Search Result

Results for "

Glutathione Reductase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Glutathione Peroxidase (12) Glutathione Reductase (1) Glutathione S-transferase (34) ADC Linker (9) Amino Acid Derivatives (3) Angiotensin Receptor (1) Apoptosis (18) Autophagy (7) Bacterial (6) Biochemical Assay Reagents (2) Calcineurin (1) Calcium Channel (9) Cholinesterase (ChE) (1) Cytochrome P450 (5) DNA Alkylator/Crosslinker (1) DNA-PK (1) Drug Metabolite (2) Endogenous Metabolite (45) Estrogen Receptor/ERR (2) Ferroptosis (25) Fluorescent Dye (5) Fungal (1) Glyoxalase (GLO) (3) HIV (1) HSV (1) Interleukin Related (1) Isotope-Labeled Compounds (15) Keap1-Nrf2 (4) Lactate Dehydrogenase (1) Lipoxygenase (1) Mitochondrial Metabolism (4) Mitophagy (1) Mucin (1) NF-κB (5) NO Synthase (3) NOD-like Receptor (NLR) (1) P-glycoprotein (1) p62 (1) Parasite (5) Phosphatase (1) Polo-like Kinase (PLK) (1) PPAR (3) PROTAC Linkers (2) PROTACs (1) Reactive Oxygen Species (23) ROS Kinase (3) STING (1) TNF Receptor (1) Virus Protease (1) α-synuclein (1)
By Research Areas:	Cancer (88) Cardiovascular Disease (14) Endocrinology (1) Infection (16) Inflammation/Immunology (32) Metabolic Disease (43) Neurological Disease (19)
Click Chemistry:	Alkynes (2)

203

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: Glutathione Reductase Glutathione Peroxidase Glutathione S-transferase Aldose Reductase 5 alpha Reductase Dihydrofolate reductase (DHFR) HMG-CoA Reductase (HMGCR) TrxR GSNOR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-125862

Glutathione Reductase, baker's yeast EC 1.6.4.2; GR	Calcineurin	Metabolic Disease
Glutathione reductase (EC 1.6.4.2) (EC 1.6.4.2) is a reductase responsible for maintaining the supply of reduced glutathione .

HY-D0844

Glutathione oxidized 4 Publications Verification L-Glutathione oxidized; GSSG; Oxiglutatione	Endogenous Metabolite Reactive Oxygen Species	Metabolic Disease
Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .

HY-P5069A

Glutathione diethyl ester TFA	Endogenous Metabolite	Metabolic Disease
Glutathione diethyl ester (TFA) is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .

HY-101131

Dansyl glutathione DNS-Glutathione	Others	Others
Dansyl glutathione is a trapping agent for the quantitative estimation and identification of reactive metabolites.

HY-W052512

Antitrypanosomal agent 1	Parasite	Infection
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC₅₀ of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC₅₀=64.8 μM) and T. brucei (EC₅₀=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity .

HY-D0844R

Glutathione oxidized (Standard)	Endogenous Metabolite Reactive Oxygen Species	Metabolic Disease
Glutathione oxidized (Standard) is the analytical standard of Glutathione oxidized. This product is intended for research and analytical applications. Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .

HY-P5069

Glutathione diethyl ester	Endogenous Metabolite	Metabolic Disease
Glutathione diethyl ester is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .

HY-130588

Glutathione arsenoxide GSAO	Mitochondrial Metabolism	Cancer
Glutathione arsenoxide (GSAO) is a potential anticancer agent and a tumour metabolism inhibitor. Glutathione arsenoxide targets Mitochondrial endomycin nucleotide transferase (ANT). Glutathione arsenoxide causes cell proliferation arrest and cell death. Glutathione arsenoxide can be used to identify cell-surface proteins, such as Protein disulphide isomerase .

HY-167920

Glutathione sulfonate S-SulfoGlutathione	Others	Cancer
Glutathione sulfonate (S-Sulfoglutathione) is a multifunctional bioactive compound that inhibits angiogenesis and tumor growth. Glutathione sulfonate is a competitive inhibitor of glutathione S-transferase and is involved in the detoxification process and the binding of a variety of exogenous and endogenous compounds. Glutathione sulfonate acts in the substrate binding site of Escherichia coli glutathione S-transferase, affecting the catalytic mechanism. The structural characteristics of Glutathione sulfonate contribute to its inhibitory effect by hydrogen bonding in the active center of the enzyme .

HY-148208

S-(p-Nitrobenzyl)glutathione	Amino Acid Derivatives	Metabolic Disease
S-(p-Nitrobenzyl)glutathione is a competitive glutathionase inhibitor. S-(p-Nitrobenzyl)glutathione is converted to the corresponding cysteine derivatives by rat kidney microsomes. S-(p-Nitrobenzyl)glutathione can be used for the research of metabolic breakdown of glutathione by the glutathionase system .

HY-134124

Glutathione ethyl ester	Reactive Oxygen Species	Inflammation/Immunology
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-144868

Glutathione synthesis-IN-1	Others	Metabolic Disease
Glutathione synthesis-IN-1 (DC-1) is a glutathione synthesis inhibitor .

HY-12590

Glutathione oxidized disodium L-Glutathione oxidized disodium; GSSG disodium; Oxiglutatione disodium	Endogenous Metabolite Reactive Oxygen Species	Metabolic Disease
Glutathione oxidized disodium is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent .

HY-137330

S-(2,4-Dinitrophenyl)glutathione	Endogenous Metabolite	Metabolic Disease
S-(2,4-Dinitrophenyl)glutathione is a substrate for glutathione-S-transferase. (2,4-Dinitrophenyl)glutathione can be used as an irreversible glutathione reductase inhibitor with an K_i value of 30 µM .

HY-N8115

S-(4-Hydroxybenzyl)glutathione	Others	Neurological Disease
S-(4-Hydroxybenzyl)glutathione is a glutathione derivative. S-(4-Hydroxybenzyl)glutathione inhibits the in vitro binding of kainic acid to brain glutamate receptors, with an IC₅₀ of 2 μM .

HY-D0187R

*L-Glutathione* reduced (Standard)**	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Glutathione reduced (Standard) is the analytical standard of L-Glutathione reduced. This product is intended for research and analytical applications. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-130588A

Glutathione arsenoxide TFA GSAO TFA	Mitochondrial Metabolism	Cancer
Glutathione arsenoxide (GSAO) TFA is a potential anticancer agent and a tumour metabolism inhibitor. Glutathione arsenoxide TFA targets Mitochondrial endomycin nucleotide transferase (ANT). Glutathione arsenoxide TFA causes cell proliferation arrest and cell death. Glutathione arsenoxide TFA can be used to identify cell-surface proteins, such as Protein disulphide isomerase .

HY-139965S

*4-hydroxy Nonenal Glutathione-d3 TFA*	Isotope-Labeled Compounds	Others
4-hydroxy Nonenal Glutathione-d₃ (TFA) is the deuterium labeled 4-hydroxy Nonenal Glutathione (TFA)[1].

HY-144403S

*S-(N-Methylcarbamoyl)glutathione-d3*	Isotope-Labeled Compounds	Others
S-(N-Methylcarbamoyl)glutathione-d₃ is the deuterium labeled S-(N-Methylcarbamoyl)glutathione[1].

HY-P2833

Glutathione Peroxidase GSH-Px; EC 1.11.1.9	Glutathione Peroxidase	Others
Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H₂O. Glutathione Peroxidase is an effective antioxidant against oxidative stress .

HY-150631S

Glutathione-glycine-13C2,15N trifluoroacetate	Isotope-Labeled Compounds	Others
Glutathione-glycine- ¹³C₂, ¹⁵N (trifluoroacetate) is the ¹³C and ¹⁵N labeled Glutathione-glycine trifluoroacetate[1].

HY-P2961

Glutathione S-transferase	Others	Others
Glutathione S-transferase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-135174

*L-Cysteine-glutathione* disulfide**	Endogenous Metabolite	Infection
L-Cysteine-glutathione disulfide is a metabolite in plasma that can be used in biomarker studies for tuberculosis cure .

HY-125737

15-deoxy-Δ12,14-Prostaglandin J2 Glutathione 15-Deoxy-Δ12,14-PGJ2 Glutathione	Others	Others
15-deoxy-Δ12,14-Prostaglandin J2 glutathione (15-deoxy-Δ12,14-PGJ2 glutathione) is a non-enzymatic adduct formed from 15-deoxy-Δ12,14-PGJ2 and glutathione. The biological properties of this compound have not been characterized.

HY-P4277

N,S-Bis-Fmoc-Glutathione	Glyoxalase (GLO)	Others
N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a K_i value of 0.32 mM .

HY-144153S

*S-(1,2-Dichlorovinyl)glutathione-13C2,15N*	Isotope-Labeled Compounds	Others
S-(1,2-Dichlorovinyl)glutathione- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled S-(1,2-Dichlorovinyl)glutathione[1].

HY-D0187

*L-Glutathione* reduced** 25+ Cited Publications GSH; γ-L-Glutamyl-L-cysteinyl-glycine	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-D0187S4

*L-Glutathione* reduced-13C** GSH-¹³C; γ-L-Glutamyl-L-cysteinyl-glycine-¹³C	Isotope-Labeled Compounds	Others
L-Glutathione reduced- ¹³C (GSH- ¹³C; γ-L-Glutamyl-L-cysteinyl-glycine- ¹³C) is ¹³C-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.

HY-D0187S5

*L-Glutathione* reduced-d2** GSH-d₂; γ-L-Glutamyl-L-cysteinyl-glycine-d₂	Isotope-Labeled Compounds	Others
L-Glutathione reduced-d₂ (GSH-d₂; γ-L-Glutamyl-L-cysteinyl-glycine-d₂) is deuterated-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.

HY-D0187B

*L-Glutathione* reduced monosodium** GSH monosodium; γ-L-Glutamyl-L-cysteinyl-glycine monosodium	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Glutathione reduced monosodium is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-D0187S6

*L-Glutathione* reduced-15N** GSH-¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine-¹⁵N	Isotope-Labeled Compounds	Others
L-Glutathione reduced- ¹⁵N (GSH- ¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine- ¹⁵N) is ¹⁵N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.

HY-D0187S

*L-Glutathione* reduced-13C2,15N** GSH-¹³C₂,¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine-¹³C₂,¹⁵N	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Glutathione reduced- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Glutathione reduced. L-Glutathione reduced (GSH) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-12542

Dantrolene 5+ Cited Publications F 368	Calcium Channel Autophagy	Neurological Disease Inflammation/Immunology
Dantrolene is an orally active, non-competitive glutathione reductase inhibitor with a K_i of 111.6 μM and an IC₅₀ of 52.3 μM. Dantrolene is a ryanodine receptor (RyR) antagonist and Ca2+ signaling stabilizer. Dantrolene is a direct-acting skeletal muscle relaxant. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome .

HY-12542A

Dantrolene sodium hemiheptahydrate 5+ Cited Publications Dantrolene sodium hydrate	Calcium Channel Autophagy	Others
Dantrolene sodium hemiheptahydrate is an orally active, non-competitive glutathione reductase inhibitor with a K_i of 111.6 μM and an IC₅₀ of 52.3 μM. Dantrolene sodium hemiheptahydrate is a ryanodine receptor (RyR) antagonist and Ca2+ signaling stabilizer. Dantrolene sodium hemiheptahydrate is a direct-acting skeletal muscle relaxant. Dantrolene sodium hemiheptahydrate can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome .

HY-12542R

Dantrolene (Standard)	Calcium Channel Autophagy	Neurological Disease Inflammation/Immunology
Dantrolene (Standard) is the analytical standard of Dantrolene. This product is intended for research and analytical applications. Dantrolene is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC₅₀ of 52.3 μM. Dantrolene is a ryanodine receptor (RyR) antagonist and Ca2+ signaling stabilizer. Dantrolene is a direct-acting skeletal muscle relaxant. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome .

HY-12542AR

Dantrolene sodium hemiheptahydrate (Standard)	Calcium Channel Autophagy	Others
Dantrolene (sodium hemiheptahydrate) (Standard) is the analytical standard of Dantrolene (sodium hemiheptahydrate). This product is intended for research and analytical applications. Dantrolene sodium hemiheptahydrate is an orally active, non-competitive glutathione reductase inhibitor with a K_i of 111.6 μM and an IC₅₀ of 52.3 μM. Dantrolene sodium hemiheptahydrate is a ryanodine receptor (RyR) antagonist and Ca2+ signaling stabilizer. Dantrolene sodium hemiheptahydrate is a direct-acting skeletal muscle relaxant. Dantrolene sodium hemiheptahydrate can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome .

HY-125006

TRi-1 2 Publications Verification	Others	Cancer
TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC₅₀ of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy .

HY-W013754

S-Hexylglutathione	Others	Others
S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against *glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase* and glutathione peroxidase .

HY-160874

GST-FH.4	Glutathione S-transferase	Metabolic Disease
GST-FH.4 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC₅₀ of 24.38 μM .

HY-160875

GST-FH.1	Glutathione S-transferase	Metabolic Disease
GST-FH.1 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC₅₀ of 0.32 μM .

HY-16123

Canfosfamide hydrochloride	DNA Alkylator/Crosslinker	Cancer
Canfosfamide (hydrochloride) is a prodrug that upon activation by glutathione s-transferase P1-1 (GSTP1-1) yields an anticancer alkylating agent and a glutathione derivative.

HY-131944

S-Acetylglutathione	Apoptosis HSV	Infection Cancer
S-Acetylglutathione is a derivative of Glutathione (HY-D0187). S-Acetylglutathione is stable in blood, and can be converted to glutathione by intracellular thioesterases. S-Acetylglutathione restores the intracellular glutathione content in glutathione synthetase deficient fibroblasts. S-Acetylglutathione exhibits antiviral efficacy in HSV-1 infected model through inhibition of viral replication. S-Acetylglutathione induces apoptosis in cancer cells MOLT4 and UKF-NB-3 .

HY-122006

NPD926	Reactive Oxygen Species	Cancer
NPD926 is a small molecule that targets glutathione and induces cancer cell death. The Xc ^- system and glutathione are therapeutic targets in cancer. NPD926 causes cellular glutathione depletion and subsequent generation of reactive oxygen species (ROS), thereby sensitizing fibroblasts to Xc ^- system inhibitors. NPD926 is a ROS inducer with anticancer activity. .

HY-113402

Gamma-glutamylcysteine 2 Publications Verification γ-Glu-Cys	Endogenous Metabolite	Inflammation/Immunology
Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels .

HY-16124

Canfosfamide TLK-286; TER286	DNA-PK Apoptosis	Cancer
Canfosfamide (TLK-286, TER286) is a glutathione analogue prodrug that is activated by glutathione S-transferase P1-1 and induces apoptosis. Canfosfamide also inhibits the catalytic kinase activity of DNA-dependent protein kinase (DNA-PK). Canfosfamide produces an anticancer alkylating agent and a glutathione derivative after activation. Canfosfamide can be used to research malignancies .

HY-W013744

S-Octylglutathione	Others	Others
S-Octylglutathione is a competitive glutathione S-transferase (GST) inhibitor .

HY-W423573

N,S-Diacetylcysteine methyl ester	Amino Acid Derivatives	Others Metabolic Disease
N,S-Diacetylcysteine methyl ester is a cysteine derivative that can increase the levels of intracellular cysteine and glutathione. N,S-Diacetylcysteine methyl ester is hydrolyzed by intracellular esterase to release cysteine, thereby promoting the synthesis of glutathione. Due to its acetylation properties, N,S-Diacetylcysteine methyl ester has better cell membrane permeability and can enter the cell more effectively. N,S-Diacetylcysteine methyl ester can be used to study the intracellular cysteine and glutathione (GSH) transport system .

HY-14943

Darinaparsin ZIO-101; S-Dimethylarsino-Glutathione	Apoptosis	Cancer
Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects .

HY-N7227

Anonaine	Glutathione S-transferase Parasite	Infection Cancer
Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .

HY-12448

SPDB	ADC Linker	Cancer
SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0844

Glutathione oxidized 4 Publications Verification L-Glutathione oxidized; GSSG; Oxiglutatione	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .

HY-P5069A

Glutathione diethyl ester TFA	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glutathione diethyl ester (TFA) is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .

HY-N8115

S-(4-Hydroxybenzyl)glutathione	Structural Classification Monophenols Gastrodia elata Bl. Ketones, Aldehydes, Acids Orchidaceae Source classification Phenols Plants	Others
S-(4-Hydroxybenzyl)glutathione is a glutathione derivative. S-(4-Hydroxybenzyl)glutathione inhibits the in vitro binding of kainic acid to brain glutamate receptors, with an IC₅₀ of 2 μM .

HY-D0187

*L-Glutathione* reduced** Maximum Cited Publications 29 Publications Verification GSH; γ-L-Glutamyl-L-cysteinyl-glycine	Cardiovascular Disease Structural Classification Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species Ferroptosis
L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-113402

Gamma-glutamylcysteine 2 Publications Verification γ-Glu-Cys	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels .

HY-N7227

Anonaine	Structural Classification Alkaloids Annona crassiflora Mart. Source classification Quinoline Alkaloids Plants Annonaceae	Glutathione S-transferase Parasite
Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .

HY-D0844R

Glutathione oxidized (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Reactive Oxygen Species
Glutathione oxidized (Standard) is the analytical standard of Glutathione oxidized. This product is intended for research and analytical applications. Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .

HY-12590

Glutathione oxidized disodium L-Glutathione oxidized disodium; GSSG disodium; Oxiglutatione disodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Glutathione oxidized disodium is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent .

HY-137330

S-(2,4-Dinitrophenyl)glutathione	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
S-(2,4-Dinitrophenyl)glutathione is a substrate for glutathione-S-transferase. (2,4-Dinitrophenyl)glutathione can be used as an irreversible glutathione reductase inhibitor with an K_i value of 30 µM .

HY-D0187R

*L-Glutathione* reduced (Standard)**	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Reactive Oxygen Species Ferroptosis
L-Glutathione reduced (Standard) is the analytical standard of L-Glutathione reduced. This product is intended for research and analytical applications. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-113402R

Gamma-glutamylcysteine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Gamma-glutamylcysteine (Standard) is the analytical standard of Gamma-glutamylcysteine. This product is intended for research and analytical applications. Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels .

HY-76082

L-Pyroglutamic acid 1 Publications Verification	Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-133199

Benastatin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Glutathione S-transferase
Benastatin A is an inhibitor of glutathione S-transferase, which can be isolated from Streptomyces MI384-DF12 .

HY-N1054

Zamanic acid 3β-Hydroxyurs-30-p-E-hydroxycinnamoyl-12-en-28-oic acid	Apocynaceae Triterpenes Structural Classification Plumeria obtusa L. Terpenoids Source classification Plants	Others
Zamanic acid is a potent inhibitor of glutathione reductase. Zamanic acid inhibits the growth of Mycobacterium tuberculosis in culture and has also been shown to have anti-inflammatory activity .

HY-W009203

L-Cystine dihydrochloride 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
L-Cystine dihydrochloride can be used as a cell culture component and is a sulfur-containing precursor of glutathione (GSH) synthesis. L-Cystine dihydrochloride homeostasis is also important for GSH functions .

HY-N11778

Bequinostatin C	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Bequinostatin C is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC₅₀=40 μg/mL for human GSTP1).

HY-N6994

Isoasatone A	Infection Acorus tatarinowii Schott Classification of Application Fields Araceae Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields	Others
Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity. Isoasatone A againsts S. litura by acting on cytochrome P450 monoxygenases and glutathione transferases .

HY-113402A

Gamma-glutamylcysteine TFA 2 Publications Verification γ-Glutamylcysteine TFA	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Interleukin Related TNF Receptor Endogenous Metabolite
Gamma-glutamylcysteine (γ-Glutamylcysteine) TFA, an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine TFA also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β). Gamma-glutamylcysteine TFA attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes .

HY-N1916

Coniferyl ferulate	Structural Classification Classification of Application Fields Simple Phenylpropanols Source classification Phenols Polyphenols Dicerothamnus rhinocerotis Phenylpropanoids Umbelliferae Plants Disease Research Fields Cancer	Glutathione S-transferase P-glycoprotein
Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST), reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM.

HY-N1282

Seneciphylline	Alkaloids Structural Classification other families Pyrrole Alkaloids Classification of Application Fields Source classification Plants Compositae Sophora yunnanensis C. Y. Ma Disease Research Fields Cancer	Glutathione S-transferase Cytochrome P450
Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and *glutathione-S-transferase* but causes reduction of cytochrome P-450 and related monooxygenase activities .

HY-76082R

L-Pyroglutamic acid (Standard)	Structural Classification Immune System Disorder Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Cardiovascular System Disorder	Endogenous Metabolite
L-Pyroglutamic acid (Standard) is the analytical standard of L-Pyroglutamic acid. This product is intended for research and analytical applications. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-Y0337

L-Cysteine 4 Publications Verification Cysteine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .

HY-W016715

L-Cysteine hydrochloride hydrate 4 Publications Verification	Structural Classification Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans .

HY-N1963

Curzerene	Curculigo orchioides Gaertn. Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Source classification Curcuma phaeocaulis Valeton Plants Amaryllidaceae Disease Research Fields Zingiberaceae Cancer	Glutathione S-transferase Apoptosis
Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis .

HY-N2560

Senecionine Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin	Pterogyne nitens Tul. Alkaloids Pyrrole Alkaloids Classification of Application Fields Erinacea anthyllis Link Source classification Metabolic Disease Plants Compositae Disease Research Fields	Others
Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) .

HY-118149A

(±)9-HpODE	Infection other families Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields	Bacterial Fungal Parasite
(±)9-HpODE is a long chain lipid hydroperoxide, is a product of linoleic acid peroxidation. (±)9-HpODE can induce oxidation of intracellular glutathione (GSH). (±)9-HpODE also exhibits antimicrobial activity against various fungal and bacterial pathogens .

HY-W017464

NAPQI	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite
NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .

HY-B1000A

L-SelenoMethionine 2 Publications Verification	Structural Classification Microorganisms other families Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

HY-N1282R

Seneciphylline (Standard)	Alkaloids Structural Classification other families Pyrrole Alkaloids Source classification Plants Compositae Sophora yunnanensis C. Y. Ma	Glutathione S-transferase Cytochrome P450
Seneciphylline (Standard) is the analytical standard of Seneciphylline. This product is intended for research and analytical applications. Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities .

HY-136386R

N-Acetyl-D-cysteine (Standard)	Microorganisms Source classification	Reactive Oxygen Species
N-Acetyl-D-cysteine (Standard) is the analytical standard of N-Acetyl-D-cysteine. This product is intended for research and analytical applications. N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .

HY-N0070

Solasonine 2 Publications Verification	Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Source classification Solanum nigrum Linn. Solanaceae Plants Disease Research Fields Cancer	Ferroptosis Glutathione Peroxidase Reactive Oxygen Species
Solasonine is a ferroptosis inducer which can be isolated from Solanum melongena that has anti-infection, anti-cancer, and neurogenesis promoting properties. Solasonine promotes ferroptosis of HCC cells via destruction of the glutathione redox system induced by inhibiting GPX4, and can be used for cancer research .

HY-N1963R

Curzerene (Standard)	Curculigo orchioides Gaertn. Structural Classification Terpenoids Sesquiterpenes Source classification Curcuma phaeocaulis Valeton Plants Amaryllidaceae Zingiberaceae	Glutathione S-transferase Apoptosis
Curzerene (Standard) is the analytical standard of Curzerene. This product is intended for research and analytical applications. Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis .

HY-W016715R

L-Cysteine hydrochloride hydrate (Standard)	Structural Classification Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
L-Cysteine (hydrochloride hydrate) (Standard) is the analytical standard of L-Cysteine (hydrochloride hydrate). This product is intended for research and analytical applications. L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans .

HY-Y0337R

L-Cysteine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
L-Cysteine (Standard) is the analytical standard of L-Cysteine. This product is intended for research and analytical applications. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .

HY-113149

Argininosuccinic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Argininosuccinic acid participates in the fourth step of the urea cycle, with being cleaved to arginine and fumaric acid by argininosuccinic acid lyase (ASL). Argininosuccinic acid reduces reduced glutathione (GSH) level, and increases the production of reactive oxygen species in cerebral cortex and striatum. Argininosuccinic acid causes lipid peroxidation and protein oxidation, and induces oxidative stress in the developing rat brain .

HY-N2560R

Senecionine (Standard)	Pterogyne nitens Tul. Alkaloids Structural Classification Pyrrole Alkaloids Erinacea anthyllis Link Source classification Plants Compositae	Others
Senecionine (Standard) is the analytical standard of Senecionine. This product is intended for research and analytical applications. Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) .

HY-N0255

alpha-Hederin α-Hederin	Triterpenes Structural Classification Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields Araliaceae	Apoptosis
alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .

HY-113149A

Argininosuccinic acid disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain .

HY-N0245

Theaflavin-3-gallate	Structural Classification Flavonoids Classification of Application Fields Flavanols Source classification Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Disease Research Fields Theaceae Cancer	Others
Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner .

HY-W024365

3-tert-Butyl-4-methoxyphenol	Structural Classification Monophenols Source classification Jatropha curcas Linn. Phenols Euphorbiaceae Plants	PROTAC Linkers
3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .

HY-N0070R

Solasonine (Standard)	Alkaloids Piperidine Alkaloids Structural Classification Source classification Solanum nigrum Linn. Solanaceae Plants	Ferroptosis Glutathione Peroxidase Reactive Oxygen Species
Solasonine (Standard) is the analytical standard of Solasonine. This product is intended for research and analytical applications. Solasonine is a ferroptosis inducer which can be isolated from Solanum melongena that has anti-infection, anti-cancer, and neurogenesis promoting properties. Solasonine promotes ferroptosis of HCC cells via destruction of the glutathione redox system induced by inhibiting GPX4, and can be used for cancer research .

HY-B1000AR

L-SelenoMethionine (Standard)	Structural Classification Microorganisms other families Animals Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite	Endogenous Metabolite Apoptosis
L-SelenoMethionine (Standard) is the analytical standard of L-SelenoMethionine. This product is intended for research and analytical applications. L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

HY-126758

Ludartin	Source classification Artemisia sieversiana Ehrhart ex Willd. Plants Compositae	Apoptosis Glutathione Peroxidase
Ludartin a sesquiterpene lactone, which can be isolated from the plant Artemisia carruthii Wood. Ludartin reduces the expression of myeloperoxidase and malondialdehyde, enhances the expression of glutathione and superoxide dismutase in spinal cord tissue. Ludartin inhibits neuronal apoptosis. Ludartin inhibits the upregulation of tumor necrosis factor-α, interleukin-1β, and interleukin-6. Ludartin improves the motor function of rats with spinal cord injury .

HY-N0548

α-Angelica lactone 2 Publications Verification	Natural Products Classification of Application Fields Source classification Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields Cancer	Glutathione S-transferase
α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .

HY-N0255R

alpha-Hederin (Standard)	Triterpenes Structural Classification Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Terpenoids Source classification Plants Araliaceae	Apoptosis
alpha-Hederin (Standard) is the analytical standard of alpha-Hederin. This product is intended for research and analytical applications. alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .

HY-Y0337A

L-Cysteine hydrochloride 4 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .

HY-106784A

(E)-Ajoene	Structural Classification Natural Products Source classification Allium sativum L. Plants Amaryllidaceae	Others
(E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .

HY-N0244R

Theaflavin-3'-gallate (Standard)	Structural Classification Flavonoids Flavanols Source classification Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Theaceae	Others
Theaflavin-3'-gallate (Standard) is the analytical standard of Theaflavin-3'-gallate. This product is intended for research and analytical applications. Theaflavin-3'-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3'-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3'-gallate reacts directly with reduced glutathione (GSH) in a time-and concentration-dependent manner .

HY-W024365R

3-tert-Butyl-4-methoxyphenol (Standard)	Structural Classification Monophenols Source classification Jatropha curcas Linn. Phenols Euphorbiaceae Plants	PROTAC Linkers
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .

HY-Y0337AR

L-Cysteine hydrochloride (Standard)	Structural Classification Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
L-Cysteine (hydrochloride) (Standard) is the analytical standard of L-Cysteine (hydrochloride). This product is intended for research and analytical applications. L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [4].

Cat. No.	Product Name	Chemical Structure

HY-76082S

L-Pyroglutamic acid-d5 1 Publications Verification
L-Pyroglutamic acid-d₅ is the deuterium labeled L-Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-113446S

Leukotriene C4-d5
Leukotriene C4-d₅ is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4.

HY-139965S

*4-hydroxy Nonenal Glutathione-d3 TFA*
4-hydroxy Nonenal Glutathione-d₃ (TFA) is the deuterium labeled 4-hydroxy Nonenal Glutathione (TFA)[1].

HY-144403S

*S-(N-Methylcarbamoyl)glutathione-d3*
S-(N-Methylcarbamoyl)glutathione-d₃ is the deuterium labeled S-(N-Methylcarbamoyl)glutathione[1].

HY-150631S

Glutathione-glycine-13C2,15N trifluoroacetate
Glutathione-glycine- ¹³C₂, ¹⁵N (trifluoroacetate) is the ¹³C and ¹⁵N labeled Glutathione-glycine trifluoroacetate[1].

HY-144153S

*S-(1,2-Dichlorovinyl)glutathione-13C2,15N*
S-(1,2-Dichlorovinyl)glutathione- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled S-(1,2-Dichlorovinyl)glutathione[1].

HY-D0187S4

*L-Glutathione* reduced-13C**
L-Glutathione reduced- ¹³C (GSH- ¹³C; γ-L-Glutamyl-L-cysteinyl-glycine- ¹³C) is ¹³C-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.

HY-D0187S5

*L-Glutathione* reduced-d2**
L-Glutathione reduced-d₂ (GSH-d₂; γ-L-Glutamyl-L-cysteinyl-glycine-d₂) is deuterated-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.

HY-D0187S6

*L-Glutathione* reduced-15N**
L-Glutathione reduced- ¹⁵N (GSH- ¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine- ¹⁵N) is ¹⁵N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.

HY-D0187S

*L-Glutathione* reduced-13C2,15N**
L-Glutathione reduced- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Glutathione reduced. L-Glutathione reduced (GSH) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-76082S1

L-Pyroglutamic acid-13C5
L-Pyroglutamic acid-13C5 is a deuterated labeled L-Pyroglutamic acid . L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-Y0337S5

L-Cysteine-d3
L-Cysteine-d₃ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S6

L-Cysteine-d2
L-Cysteine-d₂ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S1

L-Cysteine-15N
L-Cysteine- ¹⁵N is the ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S4

L-Cysteine-13C3
L-Cysteine- ¹³C₃ is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S2

L-Cysteine-3-13C
L-Cysteine-3- ¹³C is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S3

L-Cysteine-1-13C
L-Cysteine-1- ¹³C is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-124104S

Aldicarb sulfoxide-d3
Aldicarb sulfoxide-d₃ is the deuterium labled Aldicarb sulfoxide (HY-124104). Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC₅₀ of 10 μM for both in zebrafish .

HY-Y0337S

L-Cysteine-13C3,15N
L-Cysteine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S7

L-Cysteine-d3,15N
L-Cysteine-d₃, ¹⁵N is the deuterium and ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-12542S

Dantrolene-13C3

Dantrolene- ¹³C₃ is the ¹³C₃ labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks