PIN1 - peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Gene

Homo sapiens

Also known as DOD; UBL5

Gene ID: 5300 | Gene type: protein coding

About PIN1

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:9,835,318-9,849,689 (from NCBI)

This gene has 11 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 30.9), testis (RPKM 25.2) and 25 other tissues.

Summary

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and Other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This Enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]

PIN1 Products(1)

mRNA	Protein	Name
NM_006221.4	NP_006212.1	peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTPase activating protein binding	IPI IPI: Inferred from physical interaction	20179103	GOA
enables beta-catenin binding	IPI IPI: Inferred from physical interaction	11533658	GOA
enables cis-trans isomerase activity	IMP IMP: Inferred from mutant phenotype	25576397	GOA
enables mitogen-activated protein kinase kinase binding	IPI IPI: Inferred from physical interaction	20179103	GOA
enables peptidyl-prolyl cis-trans isomerase activity	EXP EXP: Inferred from Experiment	20956805	GOA
enables peptidyl-prolyl cis-trans isomerase activity	IDA IDA: Inferred from direct assay	19122240	GOA
enables phosphoserine residue binding	IDA IDA: Inferred from direct assay	10037602	GOA
enables phosphothreonine residue binding	IDA IDA: Inferred from direct assay	10037602	GOA
enables phosphothreonine residue binding	IPI IPI: Inferred from physical interaction	10037602	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	11470801	GOA
enables ubiquitin ligase activator activity	IDA IDA: Inferred from direct assay	19122240	GOA

Biological Process GO Annotation	Evidence	Reference	Source
NOT involved in microtubule polymerization	IDA IDA: Inferred from direct assay	26996940	GOA
involved in negative regulation of ERK1 and ERK2 cascade	IDA IDA: Inferred from direct assay	20179103	GOA
involved in negative regulation of SMAD protein signal transduction	IDA IDA: Inferred from direct assay	19122240	GOA
involved in negative regulation of amyloid-beta formation	IMP IMP: Inferred from mutant phenotype	25576397	GOA
involved in negative regulation of cell motility	IDA IDA: Inferred from direct assay	20179103	GOA
involved in negative regulation of protein binding	IDA IDA: Inferred from direct assay	11533658	GOA
involved in negative regulation of protein catabolic process	IDA IDA: Inferred from direct assay	11533658	GOA
involved in negative regulation of transforming growth factor beta receptor signaling pathway	IDA IDA: Inferred from direct assay	19122240	GOA
involved in positive regulation of GTPase activity	IMP IMP: Inferred from mutant phenotype	20179103	GOA
involved in positive regulation of canonical Wnt signaling pathway	IDA IDA: Inferred from direct assay	11533658	GOA
involved in positive regulation of protein binding	IDA IDA: Inferred from direct assay	24964035	GOA
acts upstream of or within positive regulation of protein phosphorylation	IGI IGI: Inferred from genetic interaction	19638580	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	11533658	GOA
involved in protein peptidyl-prolyl isomerization	IDA IDA: Inferred from direct assay	29686383	GOA
involved in protein stabilization	IDA IDA: Inferred from direct assay	11533658	GOA
acts upstream of or within regulation of cytokinesis	IGI IGI: Inferred from genetic interaction	19638580	GOA
acts upstream of or within regulation of cytokinesis	IMP IMP: Inferred from mutant phenotype	19638580	GOA
involved in regulation of gene expression	IDA IDA: Inferred from direct assay	24964035	GOA
involved in regulation of protein localization to nucleus	IDA IDA: Inferred from direct assay	11533658	GOA
involved in regulation of protein phosphorylation	IDA IDA: Inferred from direct assay	24964035	GOA
involved in regulation of protein stability	IMP IMP: Inferred from mutant phenotype	25576397	GOA
involved in response to hypoxia	IDA IDA: Inferred from direct assay	25576397	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in ciliary basal body	IDA IDA: Inferred from direct assay	29257953	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	16697218	GOA
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	28458925	GOA
located in midbody	IDA IDA: Inferred from direct assay	19638580	GOA
located in nucleus	IDA IDA: Inferred from direct assay	16697218	GOA
is active in postsynaptic cytosol	IDA IDA: Inferred from direct assay	28458925	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PIN1 Protein Structure

Rotamase

0
100
163 a.a.

Protein Preferred Names

Protein Names

peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

PPIase Pin1

PIN1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PIN1	Q13526	KRT40	Homo sapiens	Q6A162	Validated Y2H	25416956
Intra	PIN1	Q13526	KRT40	Homo sapiens	Q6A162	Y2H Array	25416956
Intra	PIN1	Q13526	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
Intra	PIN1	Q13526	HOMEZ	Homo sapiens	Q8IX15-3	Validated Y2H	25416956
Intra	PIN1	Q13526	KRTAP10-9	Homo sapiens	P60411	Y2H Array	25416956
Intra	PIN1	Q13526	KRTAP10-9	Homo sapiens	P60411	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	KRTAP10-9	Homo sapiens	P60411	Validated Y2H	25416956
Intra	PIN1	Q13526	KRTAP10-7	Homo sapiens	P60409	Y2H Array	32296183
Intra	PIN1	Q13526	KRTAP10-7	Homo sapiens	P60409	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	KRTAP10-7	Homo sapiens	P60409	Validated Y2H	25416956
Intra	PIN1	Q13526	KRTAP10-7	Homo sapiens	P60409	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KRTAP4-2	Homo sapiens	Q9BYR5	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	KRTAP4-2	Homo sapiens	Q9BYR5	Validated Y2H	25416956
Intra	PIN1	Q13526	SSC5D	Homo sapiens	A1L4H1	Y2H Array	32296183
Intra	PIN1	Q13526	SSC5D	Homo sapiens	A1L4H1	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	ADAMTSL4	Homo sapiens	Q6UY14-3	Validated Y2H	25416956
Intra	PIN1	Q13526	ZBTB14	Homo sapiens	O43829	Y2H Array	25416956
Intra	PIN1	Q13526	CCDC184	Homo sapiens	Q52MB2	Validated Y2H	32296183
Intra	PIN1	Q13526	CCDC184	Homo sapiens	Q52MB2	Y2H Array	25416956
Intra	PIN1	Q13526	CCDC184	Homo sapiens	Q52MB2	Y2H Array	32296183
Intra	PIN1	Q13526	CCDC184	Homo sapiens	Q52MB2	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	CCDC184	Homo sapiens	Q52MB2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZMIZ2	Homo sapiens	Q8NF64-2	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	BCL11A	Homo sapiens	Q9H165-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	BCL11A	Homo sapiens	Q9H165-2	Validated Y2H	32296183
Intra	PIN1	Q13526	BCL11A	Homo sapiens	Q9H165-2	Y2H Array	32296183
Intra	PIN1	Q13526	RBBP8	Homo sapiens	Q99708-2	Y2H Array	25416956
Intra	PIN1	Q13526	NONO	Homo sapiens	Q15233-2	Validated Y2H	25416956
Intra	PIN1	Q13526	NONO	Homo sapiens	Q15233-2	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	ZNF449	Homo sapiens	Q6P9G9	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZNF449	Homo sapiens	Q6P9G9	Y2H Array	32296183
Intra	PIN1	Q13526	ZNF449	Homo sapiens	Q6P9G9	Validated Y2H	32296183
Intra	PIN1	Q13526	SELENOV	Homo sapiens	P59797	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	SELENOV	Homo sapiens	P59797	Y2H Array	32296183
Intra	PIN1	Q13526	BRD8	Homo sapiens	Q9H0E9-2	Validated Y2H	32296183
Intra	PIN1	Q13526	CCDC6	Homo sapiens	Q16204	Validated Y2H	32296183
Intra	PIN1	Q13526	CCDC6	Homo sapiens	Q16204	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	CCDC6	Homo sapiens	Q16204	Y2H Array	32296183
Intra	PIN1	Q13526	KRT37	Homo sapiens	O76014	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KRT37	Homo sapiens	O76014	Y2H Array	32296183
Intra	PIN1	Q13526	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	PIN1	Q13526	KRT38	Homo sapiens	O76015	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KRT38	Homo sapiens	O76015	Y2H Array	25416956
Intra	PIN1	Q13526	KRT38	Homo sapiens	O76015	Y2H Array	32296183
Intra	PIN1	Q13526	KRT38	Homo sapiens	O76015	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	NCKIPSD	Homo sapiens	Q9NZQ3-3	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	NCKIPSD	Homo sapiens	Q9NZQ3-3	Validated Y2H	32296183
Intra	PIN1	Q13526	NCKIPSD	Homo sapiens	Q9NZQ3-3	Y2H Array	32296183
Intra	PIN1	Q13526	ZNF526	Homo sapiens	Q8TF50	Validated Y2H	32296183
Intra	PIN1	Q13526	ZNF526	Homo sapiens	Q8TF50	Y2H Array	32296183
Intra	PIN1	Q13526	ZNF526	Homo sapiens	Q8TF50	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ABI2	Homo sapiens	Q9NYB9-2	Validated Y2H	32296183
Intra	PIN1	Q13526	ABI2	Homo sapiens	Q9NYB9-2	Y2H Array	32296183
Intra	PIN1	Q13526	ABI2	Homo sapiens	Q9NYB9-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	FOXN1	Homo sapiens	O15353	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	FOXN1	Homo sapiens	O15353	Y2H Array	32296183
Intra	PIN1	Q13526	RBBP8NL	Homo sapiens	Q8NC74	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	RBBP8NL	Homo sapiens	Q8NC74	Validated Y2H	32296183
Intra	PIN1	Q13526	RBBP8NL	Homo sapiens	Q8NC74	Y2H Array	32296183
Intra	PIN1	Q13526	IKZF1	Homo sapiens	Q13422-7	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	IKZF1	Homo sapiens	Q13422-7	Y2H Array	32296183
Intra	PIN1	Q13526	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	MTUS2	Homo sapiens	Q5JR59-3	Validated Y2H	32296183
Intra	PIN1	Q13526	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
Intra	PIN1	Q13526	CBY2	Homo sapiens	Q8NA61-2	Validated Y2H	32296183
Intra	PIN1	Q13526	CBY2	Homo sapiens	Q8NA61-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	CBY2	Homo sapiens	Q8NA61-2	Y2H Array	32296183
Intra	PIN1	Q13526	EFS	Homo sapiens	O43281-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	EFS	Homo sapiens	O43281-2	Y2H Array	32296183
Intra	PIN1	Q13526	LCN2	Homo sapiens	P80188	Y2H Array	32296183
Intra	PIN1	Q13526	LCN2	Homo sapiens	P80188	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TCF12	Homo sapiens	Q99081-3	Y2H Array	32296183
Intra	PIN1	Q13526	TCF12	Homo sapiens	Q99081-3	Validated Y2H	32296183
Intra	PIN1	Q13526	TCF12	Homo sapiens	Q99081-3	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ATN1	Homo sapiens	Q86V38	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ATN1	Homo sapiens	Q86V38	Validated Y2H	32296183
Intra	PIN1	Q13526	ATN1	Homo sapiens	Q86V38	Y2H Array	32296183
Intra	PIN1	Q13526	KCTD7	Homo sapiens	Q96MP8-2	Y2H Array	32296183
Intra	PIN1	Q13526	KCTD7	Homo sapiens	Q96MP8-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KCTD7	Homo sapiens	Q96MP8-2	Validated Y2H	32296183
Intra	PIN1	Q13526	DRC12	Homo sapiens	Q494R4-2	Validated Y2H	32296183
Intra	PIN1	Q13526	DRC12	Homo sapiens	Q494R4-2	Y2H Array	32296183
Intra	PIN1	Q13526	DRC12	Homo sapiens	Q494R4-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZMIZ2	Homo sapiens	Q8NF64-3	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZMIZ2	Homo sapiens	Q8NF64-3	Validated Y2H	32296183
Intra	PIN1	Q13526	ZMIZ2	Homo sapiens	Q8NF64-3	Y2H Array	32296183
Intra	PIN1	Q13526	KRTAP10-6	Homo sapiens	P60371	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KRTAP10-6	Homo sapiens	P60371	Y2H Array	32296183
Intra	PIN1	Q13526	FOXI1	Homo sapiens	Q12951-2	Y2H Array	32296183
Intra	PIN1	Q13526	FOXI1	Homo sapiens	Q12951-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	SCYL1	Homo sapiens	Q96KG9-4	Y2H Array	32296183
Intra	PIN1	Q13526	SCYL1	Homo sapiens	Q96KG9-4	Validated Y2H	32296183
Intra	PIN1	Q13526	SCYL1	Homo sapiens	Q96KG9-4	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZNF768	Homo sapiens	Q9H5H4	Y2H Array	32296183
Intra	PIN1	Q13526	ZNF768	Homo sapiens	Q9H5H4	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZNF768	Homo sapiens	Q9H5H4	Validated Y2H	32296183
Intra	PIN1	Q13526	DAB1	Homo sapiens	O75553-5	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	DAB1	Homo sapiens	O75553-5	Y2H Array	32296183
Intra	PIN1	Q13526	ZBTB42	Homo sapiens	B2RXF5	Y2H Array	32296183
Intra	PIN1	Q13526	ZBTB42	Homo sapiens	B2RXF5	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TFPT	Homo sapiens	P0C1Z6	Y2H Array	32296183
Intra	PIN1	Q13526	TFPT	Homo sapiens	P0C1Z6	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	EYA2	Homo sapiens	O00167-2	Y2H Array	32296183
Intra	PIN1	Q13526	EYA2	Homo sapiens	O00167-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	a0a384nq31_human	Homo sapiens	A0A384NQ31	Y2H Array	32296183
Intra	PIN1	Q13526	a0a384nq31_human	Homo sapiens	A0A384NQ31	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	GPR152	Homo sapiens	Q8TDT2	Validated Y2H	32296183
Intra	PIN1	Q13526	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
Intra	PIN1	Q13526	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	NR4A3	Homo sapiens	Q92570	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	NR4A3	Homo sapiens	Q92570	Validated Y2H	32296183
Intra	PIN1	Q13526	NR4A3	Homo sapiens	Q92570	Y2H Array	32296183
Intra	PIN1	Q13526	ETV6	Homo sapiens	P41212	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ETV6	Homo sapiens	P41212	Anti Tag CoIP	33961781
Intra	PIN1	Q13526	ETV6	Homo sapiens	P41212	Y2H Array	32296183
Intra	PIN1	Q13526	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KIFC3	Homo sapiens	Q9BVG8-5	Validated Y2H	32296183
Intra	PIN1	Q13526	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Array	32296183
Cross	PIN1	Q13526	Nanog	Mus musculus	Q80Z64-1	Pull Down	20622153
Intra	PIN1	Q13526	MEOX2	Homo sapiens	Q6FHY5	Validated Y2H	32296183
Intra	PIN1	Q13526	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	PIN1	Q13526	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	CDK10	Homo sapiens	Q15131	Pull Down	22158035
Intra	PIN1	Q13526	CDK10	Homo sapiens	Q15131	Anti Bait CoIP	22158035
Intra	PIN1	Q13526	CDK10	Homo sapiens	Q15131	Anti Tag CoIP	22158035
Intra	PIN1	Q13526	AMOT	Homo sapiens	A2BDD9	Y2H Array	32296183
Intra	PIN1	Q13526	AMOT	Homo sapiens	A2BDD9	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	MYF5	Homo sapiens	P13349	Y2H Array	32296183
Intra	PIN1	Q13526	MYF5	Homo sapiens	P13349	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZNF783	Homo sapiens	Q6ZMS7-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZNF783	Homo sapiens	Q6ZMS7-2	Validated Y2H	32296183
Intra	PIN1	Q13526	ZNF783	Homo sapiens	Q6ZMS7-2	Y2H Array	32296183
Intra	PIN1	Q13526	C3orf36	Homo sapiens	Q3SXR2	Validated Y2H	32296183
Intra	PIN1	Q13526	C3orf36	Homo sapiens	Q3SXR2	Y2H Array	32296183
Intra	PIN1	Q13526	C3orf36	Homo sapiens	Q3SXR2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	UBXN2B	Homo sapiens	Q14CS0	Validated Y2H	32296183
Intra	PIN1	Q13526	BARD1	Homo sapiens	Q99728-1	Pull Down	31270457
Intra	PIN1	Q13526	BRCA1	Homo sapiens	P38398-1	Pull Down	31270457
Intra	PIN1	Q13526	TP63	Homo sapiens	Q9H3D4	Validated Y2H	32296183
Intra	PIN1	Q13526	TP63	Homo sapiens	Q9H3D4	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TP63	Homo sapiens	Q9H3D4	Y2H Array	32296183
Intra	PIN1	Q13526	ZBTB2	Homo sapiens	Q8N680	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZBTB2	Homo sapiens	Q8N680	Validated Y2H	32296183
Intra	PIN1	Q13526	ZBTB2	Homo sapiens	Q8N680	Y2H Array	32296183
Intra	PIN1	Q13526	PRRC1	Homo sapiens	Q96M27	Validated Y2H	25416956
Intra	PIN1	Q13526	PRRC1	Homo sapiens	Q96M27	Y2H Array	25416956
Intra	PIN1	Q13526	PLEKHG2	Homo sapiens	Q9H7P9	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	PLEKHG2	Homo sapiens	Q9H7P9	Validated Y2H	32296183
Intra	PIN1	Q13526	PLEKHG2	Homo sapiens	Q9H7P9	Y2H Array	32296183
Intra	PIN1	Q13526	ANKRD40	Homo sapiens	Q6AI12	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ANKRD40	Homo sapiens	Q6AI12	Y2H Array	32296183
Intra	PIN1	Q13526	ANKRD40	Homo sapiens	Q6AI12	Validated Y2H	32296183
Intra	PIN1	Q13526	MEOX1	Homo sapiens	P50221	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	MEOX1	Homo sapiens	P50221	Y2H Array	32296183
Intra	PIN1	Q13526	SP140	Homo sapiens	Q13342	NMR	24267382
Intra	PIN1	Q13526	SP140	Homo sapiens	Q13342	Anti Tag CoIP	24267382
Intra	PIN1	Q13526	PLAGL2	Homo sapiens	Q9UPG8	Y2H Array	32296183
Intra	PIN1	Q13526	PLAGL2	Homo sapiens	Q9UPG8	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	PLAGL2	Homo sapiens	Q9UPG8	Validated Y2H	32296183
Intra	PIN1	Q13526	SSBP3	Homo sapiens	Q9BWW4	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	SSBP3	Homo sapiens	Q9BWW4	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	SSBP3	Homo sapiens	Q9BWW4	Validated Y2H	25416956
Intra	PIN1	Q13526	SSBP3	Homo sapiens	Q9BWW4	Validated Y2H	32296183
Intra	PIN1	Q13526	SSBP3	Homo sapiens	Q9BWW4	Y2H Array	25416956
Intra	PIN1	Q13526	SSBP3	Homo sapiens	Q9BWW4	Y2H Array	32296183
Intra	PIN1	Q13526	ADARB1	Homo sapiens	P78563	IF	21847096
Intra	PIN1	Q13526	ADARB1	Homo sapiens	P78563	Pull Down	21847096
Intra	PIN1	Q13526	ADARB1	Homo sapiens	P78563	Anti Tag CoIP	21847096
Cross	PIN1	Q13526	Map2k1	Mus musculus	P31938	Anti Tag CoIP	20179103
Cross	PIN1	Q13526	Map2k1	Mus musculus	P31938	Anti Bait CoIP	20179103
Intra	PIN1	Q13526	PBX1	Homo sapiens	P40424	Y2H Array	32296183
Intra	PIN1	Q13526	PBX1	Homo sapiens	P40424	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	PNMA1	Homo sapiens	Q8ND90	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	PNMA1	Homo sapiens	Q8ND90	Y2H Array	25416956
Intra	PIN1	Q13526	GLI1	Homo sapiens	P08151	Y2H Array	32296183
Intra	PIN1	Q13526	GLI1	Homo sapiens	P08151	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	CCDC88B	Homo sapiens	A6NC98	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	CCDC88B	Homo sapiens	A6NC98	Y2H Array	32296183
Intra	PIN1	Q13526	NUP62	Homo sapiens	P37198	Y2H Array	32296183
Intra	PIN1	Q13526	NUP62	Homo sapiens	P37198	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	NUP62	Homo sapiens	P37198	Validated Y2H	25416956
Intra	PIN1	Q13526	NUP62	Homo sapiens	P37198	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	PDLIM7	Homo sapiens	Q9NR12	Y2H Array	32296183
Intra	PIN1	Q13526	PDLIM7	Homo sapiens	Q9NR12	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	PDLIM7	Homo sapiens	Q9NR12	Validated Y2H	32296183
Intra	PIN1	Q13526	NONO	Homo sapiens	Q15233	Y2H Array	25416956
Intra	PIN1	Q13526	NONO	Homo sapiens	Q15233	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	MAP3K8	Homo sapiens	P41279	Protein Kinase Assay	24265246
Intra	PIN1	Q13526	MAP3K8	Homo sapiens	P41279	Anti Bait CoIP	24265246
Intra	PIN1	Q13526	MAP3K8	Homo sapiens	P41279	Anti Tag CoIP	24265246
Intra	PIN1	Q13526	TRAF2	Homo sapiens	Q12933	Y2H Pooling	16189514
Intra	PIN1	Q13526	TRAF2	Homo sapiens	Q12933	Validated Y2H	25416956
Intra	PIN1	Q13526	TRAF2	Homo sapiens	Q12933	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TRAF2	Homo sapiens	Q12933	Y2H Array	32296183
Intra	PIN1	Q13526	TNIP1	Homo sapiens	Q15025	Validated Y2H	32296183
Intra	PIN1	Q13526	TNIP1	Homo sapiens	Q15025	Y2H Array	32296183
Intra	PIN1	Q13526	TNIP1	Homo sapiens	Q15025	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TNIP1	Homo sapiens	Q15025	Y2H	21988832
Intra	PIN1	Q13526	IRAK1	Homo sapiens	P51617	Pull Down	21743479
Intra	PIN1	Q13526	TRAF1	Homo sapiens	Q13077	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	TAB3	Homo sapiens	Q8N5C8	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	TAB3	Homo sapiens	Q8N5C8	Validated Y2H	25416956
Intra	PIN1	Q13526	TAB3	Homo sapiens	Q8N5C8	Y2H Array	25416956
Intra	PIN1	Q13526	RAF1	Homo sapiens	P04049	Anti Tag CoIP	20179103
Intra	PIN1	Q13526	TP53	Homo sapiens	P04637	CoIP	12397362
Intra	PIN1	Q13526	TP53	Homo sapiens	P04637	Anti Bait CoIP	21741598
Intra	PIN1	Q13526	TP53	Homo sapiens	P04637	Pull Down	17906639
Intra	PIN1	Q13526	TP53	Homo sapiens	P04637	CH-IP	17906639
Intra	PIN1	Q13526	TP53	Homo sapiens	P04637	Anti Tag CoIP	21741598
Intra	PIN1	Q13526	TP53	Homo sapiens	P04637	Y2H	21900206
Intra	PIN1	Q13526	AMOT	Homo sapiens	Q4VCS5-2	Y2H Array	25416956
Intra	PIN1	Q13526	NEUROD4	Homo sapiens	Q9HD90	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	NEUROD4	Homo sapiens	Q9HD90	Validated Y2H	32296183
Intra	PIN1	Q13526	NEUROD4	Homo sapiens	Q9HD90	Y2H Array	32296183
Intra	PIN1	Q13526	ZBTB9	Homo sapiens	Q96C00	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZBTB9	Homo sapiens	Q96C00	Y2H Array	32296183
Intra	PIN1	Q13526	ZBTB9	Homo sapiens	Q96C00	Validated Y2H	25416956
Intra	PIN1	Q13526	ZBTB9	Homo sapiens	Q96C00	Validated Y2H	32296183
Intra	PIN1	Q13526	KRTAP5-9	Homo sapiens	P26371	Y2H Array	32296183
Intra	PIN1	Q13526	KRTAP5-9	Homo sapiens	P26371	Y2H Prey Pooling	32296183
Cross	PIN1	Q13526	Map2k2	Mus musculus	Q63932	Pull Down	20179103
Cross	PIN1	Q13526	Map2k2	Mus musculus	Q63932	Anti Tag CoIP	20179103
Intra	PIN1	Q13526	SCAI	Homo sapiens	Q8N9R8	Validated Y2H	32296183
Intra	PIN1	Q13526	SCAI	Homo sapiens	Q8N9R8	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	SCAI	Homo sapiens	Q8N9R8	Y2H Array	32296183
Intra	PIN1	Q13526	MYC	Homo sapiens	P01106	NMR	26655473
Intra	PIN1	Q13526	MYC	Homo sapiens	P01106	SPR	26655473
Intra	PIN1	Q13526	MYC	Homo sapiens	P01106	ITC	26655473
Intra	PIN1	Q13526	E2F4	Homo sapiens	Q16254	Y2H Array	32296183
Intra	PIN1	Q13526	E2F4	Homo sapiens	Q16254	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	E2F4	Homo sapiens	Q16254	Validated Y2H	32296183
Intra	PIN1	Q13526	MAP2K1	Homo sapiens	Q02750	Y2H	20179161
Intra	PIN1	Q13526	MAP2K1	Homo sapiens	Q02750	Anti Tag CoIP	20179161
Intra	PIN1	Q13526	TCF4	Homo sapiens	P15884	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	TCF4	Homo sapiens	P15884	Validated Y2H	25416956
Intra	PIN1	Q13526	TCF4	Homo sapiens	P15884	Y2H Array	25416956
Intra	PIN1	Q13526	HEXIM2	Homo sapiens	Q96MH2	Y2H Array	32296183
Intra	PIN1	Q13526	HEXIM2	Homo sapiens	Q96MH2	Validated Y2H	32296183
Intra	PIN1	Q13526	HEXIM2	Homo sapiens	Q96MH2	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	HEXIM2	Homo sapiens	Q96MH2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	NELFA	Homo sapiens	Q9H3P2	Validated Y2H	32296183
Intra	PIN1	Q13526	NELFA	Homo sapiens	Q9H3P2	Y2H Array	32296183
Intra	PIN1	Q13526	NELFA	Homo sapiens	Q9H3P2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	PIN1	Q13526	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	PIN1	Q13526	GOLGA2	Homo sapiens	Q08379	Validated Y2H	25416956
Intra	PIN1	Q13526	NOTCH1	Homo sapiens	P46531	Far-WB	19151708
Intra	PIN1	Q13526	NOTCH1	Homo sapiens	P46531	Pull Down	19151708
Intra	PIN1	Q13526	SULT4A1	Homo sapiens	Q9BR01	Y2H	19439498
Intra	PIN1	Q13526	SUPT5H	Homo sapiens	O00267	Y2H	21988832
Intra	PIN1	Q13526	SUPT5H	Homo sapiens	O00267	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	SUPT5H	Homo sapiens	O00267	Y2H Array	32296183
Intra	PIN1	Q13526	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TRIM27	Homo sapiens	P14373	Y2H Array	32296183
Intra	PIN1	Q13526	ZBTB22	Homo sapiens	O15209	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	ZBTB22	Homo sapiens	O15209	Validated Y2H	25416956
Intra	PIN1	Q13526	MDFI	Homo sapiens	Q99750	Validated Y2H	25416956
Intra	PIN1	Q13526	MDFI	Homo sapiens	Q99750	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	MDFI	Homo sapiens	Q99750	Validated Y2H	32296183
Intra	PIN1	Q13526	MDFI	Homo sapiens	Q99750	Y2H Array	25416956
Intra	PIN1	Q13526	MDFI	Homo sapiens	Q99750	Y2H Array	32296183
Intra	PIN1	Q13526	TSC22D4	Homo sapiens	Q9Y3Q8	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TSC22D4	Homo sapiens	Q9Y3Q8	Y2H Pooling	16189514
Intra	PIN1	Q13526	TSC22D4	Homo sapiens	Q9Y3Q8	Validated Y2H	32296183
Intra	PIN1	Q13526	TSC22D4	Homo sapiens	Q9Y3Q8	Y2H Array	32296183
Intra	PIN1	Q13526	CBS	Homo sapiens	P35520	Y2H Array	31515488
Intra	PIN1	Q13526	CBS	Homo sapiens	P35520	Validated Y2H	25416956
Intra	PIN1	Q13526	MLLT6	Homo sapiens	P55198	Y2H Array	32296183
Intra	PIN1	Q13526	MLLT6	Homo sapiens	P55198	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZNF446	Homo sapiens	Q9NWS9-2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	ZNF446	Homo sapiens	Q9NWS9-2	Y2H Array	32296183
Intra	PIN1	Q13526	ZNF446	Homo sapiens	Q9NWS9-2	Validated Y2H	32296183
Intra	PIN1	Q13526	RBPMS	Homo sapiens	Q93062	Y2H Array	25416956
Intra	PIN1	Q13526	RBPMS	Homo sapiens	Q93062	Y2H Pooling	16189514
Intra	PIN1	Q13526	RBPMS	Homo sapiens	Q93062	Validated Y2H	25416956
Intra	PIN1	Q13526	ZBTB7B	Homo sapiens	O15156	Y2H Array	25416956
Intra	PIN1	Q13526	ZBTB7B	Homo sapiens	O15156	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	ZBTB7B	Homo sapiens	O15156	Validated Y2H	25416956
Intra	PIN1	Q13526	ARHGEF15	Homo sapiens	O94989	Validated Y2H	25416956
Intra	PIN1	Q13526	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
Intra	PIN1	Q13526	THAP7	Homo sapiens	Q9BT49	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	THAP7	Homo sapiens	Q9BT49	Y2H Array	31515488
Intra	PIN1	Q13526	CNKSR1	Homo sapiens	Q969H4	Validated Y2H	32296183
Intra	PIN1	Q13526	CNKSR1	Homo sapiens	Q969H4	Validated Y2H	25416956
Intra	PIN1	Q13526	CNKSR1	Homo sapiens	Q969H4	Y2H Array	32296183
Intra	PIN1	Q13526	CNKSR1	Homo sapiens	Q969H4	Y2H Array	25416956
Intra	PIN1	Q13526	CNKSR1	Homo sapiens	Q969H4	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TRIP6	Homo sapiens	Q15654	Y2H Array	25416956
Intra	PIN1	Q13526	TRIP6	Homo sapiens	Q15654	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	CEP76	Homo sapiens	Q8TAP6	Validated Y2H	32296183
Intra	PIN1	Q13526	CEP76	Homo sapiens	Q8TAP6	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	CEP76	Homo sapiens	Q8TAP6	Y2H Array	32296183
Intra	PIN1	Q13526	MTUS2	Homo sapiens	Q5JR59	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	MTUS2	Homo sapiens	Q5JR59	Validated Y2H	25416956
Intra	PIN1	Q13526	MTUS2	Homo sapiens	Q5JR59	Y2H Array	25416956
Intra	PIN1	Q13526	ABI2	Homo sapiens	Q9NYB9	Validated Y2H	25416956
Intra	PIN1	Q13526	ABI2	Homo sapiens	Q9NYB9	Y2H Array	25416956
Intra	PIN1	Q13526	ABI2	Homo sapiens	Q9NYB9	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	ABI2	Homo sapiens	Q9NYB9	Y2H Array	29892012
Intra	PIN1	Q13526	RAI1	Homo sapiens	Q7Z5J4	Y2H Pooling	16189514
Intra	PIN1	Q13526	RAI1	Homo sapiens	Q7Z5J4	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	FOSL1	Homo sapiens	P15407	Y2H Array	32296183
Intra	PIN1	Q13526	FOSL1	Homo sapiens	P15407	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	SSBP4	Homo sapiens	Q9BWG4	Y2H Array	32296183
Intra	PIN1	Q13526	SSBP4	Homo sapiens	Q9BWG4	Y2H	21516116
Intra	PIN1	Q13526	SSBP4	Homo sapiens	Q9BWG4	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	SSBP4	Homo sapiens	Q9BWG4	Validated Y2H	32296183
Intra	PIN1	Q13526	IKZF1	Homo sapiens	Q13422	Validated Y2H	25416956
Intra	PIN1	Q13526	ZMIZ2	Homo sapiens	Q8NF64	Y2H Pooling	16189514
Intra	PIN1	Q13526	ZMIZ2	Homo sapiens	Q8NF64	Y2H Array	25416956
Intra	PIN1	Q13526	IKZF3	Homo sapiens	Q9UKT9	Validated Y2H	25416956
Intra	PIN1	Q13526	IKZF3	Homo sapiens	Q9UKT9	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	IKZF3	Homo sapiens	Q9UKT9	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	IKZF3	Homo sapiens	Q9UKT9	Validated Y2H	32296183
Intra	PIN1	Q13526	IKZF3	Homo sapiens	Q9UKT9	Y2H Array	32296183
Intra	PIN1	Q13526	PAX6	Homo sapiens	P26367	Y2H Array	32296183
Intra	PIN1	Q13526	PAX6	Homo sapiens	P26367	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	CEP55	Homo sapiens	Q53EZ4	Y2H Array	25416956
Intra	PIN1	Q13526	CEP55	Homo sapiens	Q53EZ4	Validated Y2H	25416956
Intra	PIN1	Q13526	CEP55	Homo sapiens	Q53EZ4	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	MEOX2	Homo sapiens	P50222	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	MEOX2	Homo sapiens	P50222	Y2H Array	25416956
Intra	PIN1	Q13526	MEOX2	Homo sapiens	P50222	Validated Y2H	25416956
Intra	PIN1	Q13526	FHL5	Homo sapiens	Q5TD97	Validated Y2H	32296183
Intra	PIN1	Q13526	FHL5	Homo sapiens	Q5TD97	Y2H Array	32296183
Intra	PIN1	Q13526	FHL5	Homo sapiens	Q5TD97	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	RNF208	Homo sapiens	Q9H0X6	Validated Y2H	32296183
Intra	PIN1	Q13526	RNF208	Homo sapiens	Q9H0X6	Y2H Array	32296183
Intra	PIN1	Q13526	RNF208	Homo sapiens	Q9H0X6	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	JAKMIP2	Homo sapiens	Q96AA8	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	JAKMIP2	Homo sapiens	Q96AA8	Y2H Array	25416956
Intra	PIN1	Q13526	INO80E	Homo sapiens	Q8NBZ0	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	INO80E	Homo sapiens	Q8NBZ0	Validated Y2H	32296183
Intra	PIN1	Q13526	INO80E	Homo sapiens	Q8NBZ0	Y2H Array	32296183
Intra	PIN1	Q13526	DAB1	Homo sapiens	O75553	Validated Y2H	25416956
Intra	PIN1	Q13526	FOS	Homo sapiens	P01100	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	FOS	Homo sapiens	P01100	Y2H Array	32296183
Intra	PIN1	Q13526	NAB2	Homo sapiens	Q15742	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	NAB2	Homo sapiens	Q15742	Validated Y2H	32296183
Intra	PIN1	Q13526	NAB2	Homo sapiens	Q15742	Y2H Array	25416956
Intra	PIN1	Q13526	NAB2	Homo sapiens	Q15742	Y2H Array	32296183
Cross	PIN1	Q13526	Grm5	Mus musculus	Q3UVX5	NMR	23911326
Intra	PIN1	Q13526	FUCA2	Homo sapiens	Q9BTY2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	FUCA2	Homo sapiens	Q9BTY2	Validated Y2H	32296183
Intra	PIN1	Q13526	FUCA2	Homo sapiens	Q9BTY2	Y2H Array	32296183
Intra	PIN1	Q13526	NUP35	Homo sapiens	Q8NFH5	Validated Y2H	32296183
Intra	PIN1	Q13526	NUP35	Homo sapiens	Q8NFH5	Y2H Array	32296183
Intra	PIN1	Q13526	NUP35	Homo sapiens	Q8NFH5	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183
Intra	PIN1	Q13526	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183
Intra	PIN1	Q13526	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	PIN1	Q13526	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	KRT31	Homo sapiens	Q15323	Validated Y2H	32296183
Intra	PIN1	Q13526	GMEB2	Homo sapiens	Q9UKD1	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	GMEB2	Homo sapiens	Q9UKD1	Y2H Array	32296183
Intra	PIN1	Q13526	GMEB2	Homo sapiens	Q9UKD1	Validated Y2H	32296183
Intra	PIN1	Q13526	ARID5A	Homo sapiens	Q03989	Y2H Array	32296183
Intra	PIN1	Q13526	ARID5A	Homo sapiens	Q03989	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	TNS2	Homo sapiens	Q63HR2	Validated Y2H	32296183
Intra	PIN1	Q13526	TNS2	Homo sapiens	Q63HR2	Y2H Array	32296183
Intra	PIN1	Q13526	TNS2	Homo sapiens	Q63HR2	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	AJUBA	Homo sapiens	Q96IF1	Y2H Prey Pooling	32296183
Intra	PIN1	Q13526	AJUBA	Homo sapiens	Q96IF1	Validated Y2H	32296183
Intra	PIN1	Q13526	AJUBA	Homo sapiens	Q96IF1	Y2H Array	32296183
Intra	PIN1	Q13526	ARHGAP8	Homo sapiens	P85298-4	Anti Tag CoIP	20179103
Intra	PIN1	Q13526	ARHGAP8	Homo sapiens	P85298-4	Anti Bait CoIP	20179103
Intra	PIN1	Q13526	ARHGAP8	Homo sapiens	P85298-4	Pull Down	20179103
Intra	PIN1	Q13526	RUNX2	Homo sapiens	Q13950	Pull Down	24113655
Intra	PIN1	Q13526	RUNX2	Homo sapiens	Q13950	Anti Tag CoIP	24113655
Intra	PIN1	Q13526	RUNX2	Homo sapiens	Q13950	Anti Bait CoIP	24113655
Intra	PIN1	Q13526	FOXP2	Homo sapiens	O15409	Y2H Array	32296183
Intra	PIN1	Q13526	FOXP2	Homo sapiens	O15409	Y2H Prey Pooling	25416956
Intra	PIN1	Q13526	FOXP2	Homo sapiens	O15409	Y2H Prey Pooling	32296183
Cross	PIN1	Q13526	Grm5	Rattus norvegicus	P31424-2	Anti Tag CoIP	23911326

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PIN1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76546	PIN1 Protein, Human	Q13526 (M1-E163)	≥95%

PIN1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81890	PIN1 Antibody (YA1635)	WB, ICC/IF	Human, Mouse, Rat

Related Diseases

Diseases

Alias

Frontotemporal Dementia

Pallidopontonigral Degeneration	Frontotemporal Lobar Degeneration
Semantic Dementia	FTD
Frontotemporal Lobe Dementia	Multiple System Tauopathy With Presenile Dementia
Dementia, Frontotemporal	Frontotemporal Dementia With Parkinsonism
Mstd	Frontotemporal Lobar Degeneration With Tau Inclusions
Ftld With Tau Inclusions	Dementia, Frontotemporal, With Parkinsonism
Fldem	Ftdp17
Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex	Ddpac
Wilhelmsen-Lynch Disease	Wld
Ppnd	Dementia, Frontotemporal, With Or Without Parkinsonism
Semantic Primary Progressive Aphasia	Semantic Variant Ppa
Wilhemsen-Lynch Disease	Frontotemporal Dementia-Amyotrophic Lateral Sclerosis
Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17	Ftd-Als
Ftld	Pick Complex
Pick Disease Of The Brain	Frontotemporal Dementia With Parkinsonism-17
Grn-Related Frontotemporal Dementia	Frontotemporal Dementia With Motor Neuron Disease
Dementia In Fronto-Temporal Lobar Degeneration	Ftd - [Frontotemporal Dementia]
Temple Dementia	Frontal Lobe Dementia

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Alzheimer Disease, Familial, 1

Alzheimer Disease	Alzheimer'S Disease
Presenile And Senile Dementia	AD1
Alzheimer Disease, Susceptibility To	Alzheimer Disease, Late-Onset, Susceptibility To
Alzheimer Disease 1, Familial	AD
Familial Alzheimer Disease	Alzheimer Disease, Late-Onset
Alzheimers Dementia	Alzheimer Dementia
Alzheimer Sclerosis	Alzheimer Syndrome
Alzheimer-Type Dementia	Dat
Primary Senile Degenerative Dementia	Sdat
Alzheimer Disease 1	Autosomal Dominant Alzheimer Disease
Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy	Late Onset Alzheimer Disease
Alzheimers Disease	Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy
Late-Onset Alzheimers Disease	Alzheimer'S Disease Pathway Kegg
Dementia Due To Alzheimer'S Disease	Alzheimer Disease Type 1
Alzheimers

Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic	Acute Myeloblastic Leukemia Type 3
Aml M3	APL
Leukemia, Acute Promyelocytic, Somatic	Aml With T(15
17)(Q22	Q12)
(Pml/Raralpha) And Variants	Apml
Acute Myeloblastic Leukemia 3	Acute Myeloid Leukemia With T(15
17)(Q22	Q12)
(Pml/Raralpha) And Variants	Acute Myeloblastic Leukaemia Type 3
Acute Myeloid Leukaemia M3	Acute Myeloid Leukemia M3
Acute Promyelocytic Leukaemia	M3 Anll
Myeloid Leukemia, Acute, M3	Leukemia Promyelocytic Acute
Leukemia, Promyelocytic, Acute	Leukemia, Acute, Promyelocytic

Short-Rib Thoracic Dysplasia 1 With Or Without Polydactyly

Asphyxiating Thoracic Dystrophy 1	Jeune Syndrome
SRTD1	Atd1
Asphyxiating Thoracic Dystrophy Of The Newborn	Jatd
Jeune Asphyxiating Thoracic Dystrophy	Thoracic-Pelvic-Phalangeal Dystrophy
Atd	Asphyxiating Thoracic Dystrophy
Chondroectodermal Dysplasia-Like Syndrome	Infantile Thoracic Dystrophy
Jeune'S Syndrome	Thoracic Pelvic Phalangeal Dystrophy
Jeune Thoracic Dystrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (18)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-139361	Sulfopin	Inhibitor	99.69%	Unkown
HY-123847	KPT-6566	Inhibitor	≥98.0%	Unkown
HY-128034	PPIase-Parvulin inhibitor	Inhibitor	99.79%	Unkown
HY-153675	BCPA	Modulator	98.51%	Unkown
HY-P4359	Suc-AEPF-AMC	Inhibitor	98.67%	Unkown
HY-128592	TAB29	Inhibitor	/	Unkown
HY-170766	PIN1 inhibitor 4	Inhibitor	/	Unkown
HY-143903	ZL-Pin13	Inhibitor	/	Unkown
HY-170429	BJP-07-017-3	Inhibitor	/	Unkown
HY-168037	PROTAC PIN1 degrader-1		/	Unkown
HY-137122	3-Pyridine toxoflavin	Inhibitor	/	Unkown
HY-168872	API32	Inhibitor	/	Unkown
HY-168036	PIN1 inhibitor 3	Inhibitor	/	Unkown
HY-164895	PIN1 degrader-1	Degrader	/	Unkown
HY-143902	ZL-Pin01	Inhibitor	/	Unkown
HY-129310	PIN1 inhibitor 5	Inhibitor	/	Unkown
HY-W843265	PIN1 inhibitor 6	Inhibitor	/	Unkown
HY-12135	Poloxipan	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PIN1	RGD	RGD:1310299
Felis catus	PIN1	VGNC	VGNC:97557
Canis familiaris	PIN1	VGNC	VGNC:81920
Mus musculus	PIN1	MGD	MGI:1346036
Bos taurus	PIN1	VGNC	VGNC:97301
Others	PIN1	NCBI

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