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Results for "

GABA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	GABA Receptor (223) 5-HT Receptor (4) Adenosine Receptor (1) Akt (1) Amyloid-β (3) Apoptosis (7) Autophagy (1) Bacterial (4) Beta-secretase (1) Biochemical Assay Reagents (6) Calcium Channel (9) Chloride Channel (6) Cholinesterase (ChE) (1) COX (1) Cytochrome P450 (3) Dopamine Receptor (5) Drug Metabolite (1) Drug-Linker Conjugates for ADC (1) Endogenous Metabolite (20) ERK (2) Fluorescent Dye (1) Fungal (2) Glutathione S-transferase (1) Glyoxalase (GLO) (1) Histamine Receptor (1) HIV (2) iGluR (7) Influenza Virus (1) Interleukin Related (2) Isotope-Labeled Compounds (15) JNK (1) Leukotriene Receptor (1) Lipoxygenase (1) MMP (1) nAChR (2) NO Synthase (2) Opioid Receptor (2) Parasite (13) Platelet-activating Factor Receptor (PAFR) (1) Potassium Channel (3) PROTAC Linkers (1) Reactive Oxygen Species (4) RSV (2) Sodium Channel (8) Somatostatin Receptor (1) TNF Receptor (2) Topoisomerase (1) Trk Receptor (2) TRP Channel (2)
By Research Areas:	Cancer (29) Cardiovascular Disease (3) Endocrinology (1) Infection (22) Inflammation/Immunology (22) Metabolic Disease (14) Neurological Disease (219)
Click Chemistry:	Alkynes (2)

288

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: GABA Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0057

Gabapentin 5+ Cited Publications	Calcium Channel	Neurological Disease Cancer
Gabapentin is a potent, orally active P/Q type Ca ²⁺ channel blocker. Gabapentin inhibits neuronal Ca ²⁺ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain .

HY-A0057A

Gabapentin hydrochloride 5+ Cited Publications	Calcium Channel	Neurological Disease Cancer
Gabapentin hydrochloride is a potent, orally active P/Q type Ca ²⁺ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca ²⁺ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain .

HY-147982

GABA-AT-IN-1	GABA Receptor	Neurological Disease
GABA-AT-IN-1 (Compound 6) is a γ-aminobutyric acid aminotransferase (GABA-AT) inhibitor and significantly elevates the mouse brain GABA level. GABA-AT-IN-1 has the ability to cross the BBB and can be used as an anticonvulsant .

HY-149399

GABA-IN-1	GABA Receptor	Infection
GABA-IN-1 (Compound 6) is a *GABA* inhibitor. GABA-IN-1 has larvicidal activity and insecticidal effect, with mortality rates of 93% at 50 mg/L .

HY-149400

GABA-IN-2	GABA Receptor	Infection
GABA-IN-2 (Compound 5) is a *GABA* inhibitor. GABA-IN-2 has larvicidal activity and insecticidal effect, with mortality rates of 87% at 50 mg/L .

HY-161589

GABA/KLH	Biochemical Assay Reagents	Inflammation/Immunology
GABA/KLH is an antigen-adjuvant conjugate formed by the coupling of GABA (γ-aminobutyric acid) with keyhole limpet hemocyanin (KLH). By coupling the antigen with a protein adjuvant, it can enhance the production of antigen-specific antibodies in vaccine models. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.

HY-161588

GABA/BSA	Biochemical Assay Reagents	Inflammation/Immunology
GABA/BSA is an antigen-adjuvant conjugate formed by the coupling of GABA (γ-aminobutyric acid) with Bovine Serum Albumin (BSA). By coupling the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.

HY-156339

GABA receptor Antagonist 1	GABA Receptor	Others
GABA receptor Antagonist 1 (compound 7w) inhibits Px RDL1 GABAR with an IC₅₀ value of 7.08 nmol/L. GABA receptor Antagonist 1 shows insecticide activity against P. xylostella, S. frugiperda, S. exigua, and S. litura, with LC₅₀ of 0.09, 0.84, 0.87, and 0.68 mg/L respectively. GABA receptor Antagonist 1 shows a medium toxicity to honeybee (48 h, ID₅₀ = 2.22 μg/adult), and low toxicity to zebrafish (LC₅₀: 42.4 mg/L) .

HY-A0057R

Gabapentin (Standard)	Calcium Channel	Neurological Disease Cancer
Gabapentin (Standard) is the analytical standard of Gabapentin. This product is intended for research and analytical applications. Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain .

HY-147736

GABAA receptor agonist 2	GABA Receptor	Neurological Disease
GABAA receptor agonist 2 (compound 4c) is a potent GABAA receptor agonist. GABAA receptor agonist 2 shows anti-depression activities in classical mouse models of depression of FST and TST. GABAA receptor agonist 2 binds at the GABA binding site of GABAA receptor in order to produce GABAergic effects. GABAA receptor agonist 2 has the potential for the research of depression .

HY-103533

Gabazine 5+ Cited Publications SR95531	GABA Receptor	Neurological Disease
Gabazine is a selective and competitive antagonist of GABA_A receptor, with an IC₅₀ of ~0.2 μM for GABA receptor.

HY-117256

Gabazine free base SR95531 free base	GABA Receptor	Inflammation/Immunology
Gabazine is a selective and competitive antagonist of GABA_A receptor, with an IC₅₀ of 0.2 μM for GABA receptor .

HY-103513

GABAA receptor agent 2	GABA Receptor	Others
GABAA receptor agent 2 (compound 13) is a compound used to study the structure and orthosteric ligand binding of GABA(A) receptors. The relevant model of GABAA receptor agent 2 can be used to understand the details of orthosteric ligand binding, and a detailed binding mode hypothesis was created through structure-activity relationships with two homologous series of orthosteric GABA(A)R antagonists.

HY-A0057S

Gabapentin-d4	Calcium Channel	Neurological Disease
Gabapentin-d₄ is the deuterium labeled Gabapentin. Gabapentin (Neurontin) is a pharmaceutical agent, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain.

HY-A0057AS2

Gabapentin-d4 hydrochloride	Isotope-Labeled Compounds Calcium Channel	Neurological Disease Cancer
Gabapentin-d4 hydrochloride is the deuterium labeled Gabapentin hydrochloride (HY-A0057A). Gabapentin hydrochloride is a potent, orally active P/Q type Ca ²⁺ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca ²⁺ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain .

HY-147735

GABAA receptor agonist 1	GABA Receptor	Neurological Disease
GABAA receptor agonist 1 (compound 3e) is a potent GABAA receptor agonist. GABAA receptor agonist 1 shows anti-depression activities in classical mouse models of depression of FST and TST. GABAA receptor agonist 1 binds at the GABA binding site of GABAA receptor in order to produce GABAergic effects. GABAA receptor agonist 1 has the potential for the research of depression .

HY-135482

GABAA receptor agent 2 TFA	GABA Receptor	Neurological Disease
GABAA receptor agent 2 TFA is a potent and high-affinity GABA_A receptor antagonist with an IC₅₀ of 24 nM (human α1β2γ2 GABA_A-expressing tsA201 cells) and a K_i of 28 nM (rat GABA_A receptors). GABAA receptor agent 2 TFA is inactive against four human GABA transporters (hGAT-1, hBGT-1, hGAT-2, and hGAT-3) .

HY-103526

DPNI-GABA	GABA Receptor	Neurological Disease
DPNI-GABA is a nitroindoline cage compound that inhibits *GABA(A)* receptors and reduces GABA-evoked peak responses with an IC₅₀ value of 0.5 mM .

HY-103527

RuBi-GABA	GABA Receptor	Neurological Disease
RuBi-GABA is a new ruthenium-based caged GABA compound. RuBi-GABA photocleaves and releases GABA after being excited with visible wavelengths. RuBi-GABA produces gaba receptor-mediated currents .

HY-131693A

*γ-Acetylenic GABA* hydrochloride** GAG hydrochloride	GABA Receptor	Neurological Disease Cancer
γ-Acetylenic GABA (GAG) hydrochloride is an irreversible inhibitor of *GABA-transaminase. γ-Acetylenic GABA* hydrochloride can increase the concentration of GABA in rat brain . γ-Acetylenic GABA (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-131693

γ-Acetylenic GABA GAG	GABA Receptor	Neurological Disease Cancer
γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is an irreversible inhibitor of *GABA-transaminase. γ-Acetylenic GABA* can increase the concentration of GABA in rat brain . γ-Acetylenic GABA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-15399

Vigabatrin 5+ Cited Publications γ-Vinyl-GABA	GABA Receptor	Neurological Disease
Vigabatrin (γ-Vinyl-GABA), an inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase .

HY-B0033

Vigabatrin hydrochloride 5+ Cited Publications γ-Vinyl-GABA hydrochloride	GABA Receptor	Neurological Disease
Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase .

HY-115685

3-Methyl-GABA	GABA Receptor	Neurological Disease
3-Methyl-GABA is a potent *GABA* aminotransferase activator. 3-Methyl-GABA can fit the binding pocket of GABA_A receptor (GABAaR). 3-Methyl-GABA can activate L-glutamic acid decarboxylase (GAD). 3-Methyl-GABA has anticonvulsant activity .

HY-103507

N-Arachidonyl-GABA	GABA Receptor	Neurological Disease
N-Arachidonoyl-GABA is one member of a new class of lipoamino acids related to anandamide identified in bovine brain. N-Arachidonoyl-GABA displays analgesic activity .

HY-101411

4-Acetamidobutanoic acid 1 Publications Verification N-acetyl GABA	GABA Receptor Endogenous Metabolite Bacterial	Others
4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of *GABA*, exhibits antioxidant and antibacterial activities .

HY-D2341

*6FC-GABA-Taxol*	Fluorescent Dye	Cancer
6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .

HY-W004697

*Boc-GABA-OH*	PROTAC Linkers	Cancer
Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC .

HY-108403

Phenibut β-Phenyl-GABA; 4-Amino-3-phenylbutanoic acid	GABA Receptor	Neurological Disease
Phenibut (β-Phenyl-GABA) is a *GABA-B* agonist . Phenibut acts as a GABA-mimetic, primarily at GABAB?receptors. Phenibut has anxiolytic and nootropic (cognition enhancing) effects .

HY-160649

*MC-Gly-Gly-Phe-Gly-GABA-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-Gly-Gly-Phe-Gly-GABA-Exatecan is an agent linker conjugate for ADC, with an inhibitor for Topoisomerase Exatecan (HY-13631) with IC₅₀ of 22 μM. MC-Gly-Gly-Phe-Gly-GABA-Exatecan targets various antibodies, exhibits cytotoxic and antitumor efficacy in vitro and in vivo .

HY-W041333

Phenibut hydrochloride β-Phenyl-GABA hydrochloride; 4-Amino-3-phenylbutanoic acid hydrochloride; 4-Amino-3-phenylbutyric acid hydrochloride	GABA Receptor	Neurological Disease
Phenibut (β-Phenyl-GABA) hydrochloride is an orally active *GABA-B* agonist . Phenibut hydrochloride acts as a GABA-mimetic, primarily at GABAB?receptors. Phenibut hydrochloride has anxiolytic and nootropic (cognition enhancing) effects .

HY-B0033S

Vigabatrin-13C,d2 hydrochloride γ-Vinyl-GABA-¹³C,d₂ hydrochloride	Isotope-Labeled Compounds GABA Receptor	Neurological Disease
Vigabatrin- ¹³C,d₂ (hydrochloride) is the ¹³C- and deuterium labeled Vigabatrin (hydrochloride). Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase[1][2][3].

HY-W010078

Ethyl 4-aminobutanoate hydrochloride H-GABA-OEt·HCl	Biochemical Assay Reagents	Others
Ethyl 4-aminobutanoate hydrochloride (H-GABA-OEt·HCl) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-15399R

Vigabatrin (Standard)	GABA Receptor	Neurological Disease
Vigabatrin (Standard) is the analytical standard of Vigabatrin. This product is intended for research and analytical applications. Vigabatrin (γ-Vinyl-GABA), an inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase .

HY-155381

APS3	GABA Receptor nAChR	Others
APS3 is a *GABA* and nACh receptors inhibitor, with a LC₅₀ of 7.2423 μg/mL against Plutella xylostella .

HY-14856

Atagabalin PD 0200390	GABA Receptor	Neurological Disease
Atagabalin (PD 0200390) is a selective *GABA* (gamma-aminobutyric acid) receptor agonist with antianxiety and sedative effects. Atagabalin enhances the activity of the *GABA* receptor by binding to the α2δ subunit of the *GABA* receptor, thereby increasing the *GABA* mediated inhibition. This enhancement results in reduced excitability of neurons, helping to reduce anxiety and improve sleep. Atagabalin can be used to study neuropsychiatric disorders, anxiety or sleep disorders .

HY-118490

T-2000 DMMDPB	GABA Receptor	Neurological Disease
T-2000 (DMMDPB) is an orally active GABA receptor agonist with anticonvulsant activities .

HY-101411S

4-Acetamidobutanoic acid-d3 N-acetyl GABA-d₃	Bacterial GABA Receptor Endogenous Metabolite Isotope-Labeled Compounds	Others
4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of *GABA*, exhibits antioxidant and antibacterial activities .

HY-14856A

iso-Atagabalin hydrochloride iso-PD 0200390 hydrochloride	GABA Receptor	Others
iso-Atagabalin (iso-PD 0200390) hydrochloride is a stereoisomer of Atagabalin (HY-14856). Atagabalin is a selective GABA (gamma-aminobutyric acid) receptor agonist with antianxiety effect .

HY-19438

Divaplon RU 32698	GABA Receptor	Neurological Disease
Divaplon is a *GABA* receptor agonist with the EC₅₀ values of 31 and 2 nM for α3β2γ2 and α5β2γ2, respectively. Divaplon shows anxiolytic activity .

HY-W008645

NCS-382 sodium	GABA Receptor	Neurological Disease
NCS-382 (sodium) is a potent *GABA* receptor antagonist. NCS-382 (sodium) has anti-sedative and anti-hypnotic activities and can be used in research related to neurological diseases .

HY-116910

CPP-115	GABA Receptor	Neurological Disease
CPP-115 is a GABA transaminase inactivator with higher affinity and lower retinal toxicity than Vigabatrin (HY-15399). CPP-115 increases brain GABA levels by inhibiting GABA transaminase catabolism. CPP-115 can be used in the study of drug addiction and infantile spasms .

HY-129464

NO-711ME	GABA Receptor	Neurological Disease
NO-711ME is a prodrug of NO-711. NO-711 is a potent and selective GABA uptake inhibitor .

HY-P2602

α-Casozepine	GABA Receptor	Neurological Disease
α-Casozepine is a bioactive peptide derived from the α protein S1 casein in milk and has an affinity for γ-aminobutyric acid (GABA) receptors in the brain. α-Casozepine has anti-anxiety effects .

HY-118259

L-663581 FG-8205	GABA Receptor	Neurological Disease
L-663581 (FG-8205) is an agonist of benzodiazepine receptor, acting as a partial agonist at GABA A receptor .

HY-100800

TACA trans-4-Aminocrotonic acid	GABA Receptor	Neurological Disease
TACA (trans-4-Aminocrotonic acid) is a potent agonist of GABA_A and GABA_C receptors (K_D= 0.6 μM). TACA also is GABA uptake inhibitor and substrate for GABA-T. TACA produces late biphasic responses in the MPG neurons .

HY-69359

Nipecotic acid (±)-β-Homoproline; Hexahydronicotinic acid; 3-Carboxypiperidine	GABA Receptor	Neurological Disease
Nipecotic acid ((±)-β-Homoproline) is a potent inhibitor of neuronal and glial-aminobutyric acid (GABA) uptake in vitro. Nipecotic acid can also directly activate GABA_A-like chloride channels, with an EC₅₀ of approximately 300?μM .

HY-N9407

Guvacine ethyl ester	GABA Receptor	Others
Guvacine ethyl ester (3.1b) is an alkaloid that can be found in betel nut. Guvacine ethyl ester can be used in the synthesis of GABA uptake inhibitor .

HY-114883

Homocarnosine L-Homocarnosine; γ-Aminobutyryl-L-histidine	GABA Receptor Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects .Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

HY-124030

3-Hydroxyphenazepam	Drug Metabolite	Neurological Disease
3-Hydroxyphenazepam is an active metabolite of Cinazepam. Cinazepam is a GABAA receptor agonist. 3-Hydroxyphenazepam can inhibit synaptosomal transporter-mediated [ ³H]GABA uptake .

Cat. No.	Product Name

HY-L120

GABA Receptor Compound Library

158 compounds

GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory neurotransmitter in the vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors), whereas GABAB receptors are G protein-coupled receptors (also known asmetabotropic receptors). GABA receptors are significant drug targets in the treatment of neuropsychiatric disorders such as epilepsy, insomnia, and anxiety, as well as in anesthesia in surgical operations.

MCE offers a unique collection of 158 GABA receptors inhibitors and activators, which is an efficient tool for neuropsychiatric disorders drugs discovery.

HY-L149

Membrane Protein-targeted Compound Library

8,013 compounds

A membrane protein is a protein molecule that is attached to or associated with the membrane of a cell or an organelle. Membrane proteins can be classified into two groups based on how the protein is associated with the membrane: integral membrane proteins and peripheral membrane proteins. In humans, about 30% genome encodes membrane proteins. Membrane proteins perform a variety of functions vital to the survival of organisms, for example, signal transduction, molecules or ion transportation, enzymatic catalysis, and intercellular communication. Membrane proteins also play important roles in drug discovery. As reported, more than 60% of current drug targets are membrane proteins.

MCE supplies a unique collection of 8,013 compounds targeting a variety of membrane proteins. MCE Membrane Protein-targeted Compound Library can be used for membrane protein-focused screening and drug discovery.

HY-L070

Neuroprotective Compound Library

1,225 compounds

Neurodegenerative diseases are characterised by progressive dysfunction and death of neurons, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis (MS). Neuroprotection is an approach to preserve neurons so that neurons cannot be hurt by different pathological factors in neurodegenerative diseases. Neuroprotectors are some agonists and antagonists targeting some key targets in neuroprotactive signal pathways, such as calcium and sodium channel blockers, GABA receptor agonists, NMDA receptor Antagonists, etc. Current neuroprotectors cannot reverse existing damage, but they may protect against further nerve damage and slow down any degeneration of the central nervous system (CNS) and still play important roles in the treatment of neurodegenerative diseases.

MCE offers a unique collection of 1,225 compounds with potential neuroprotective activities. These compounds mainly act on some key targets in neuroprotetive signal pathways, such as calcium channel, sodium channel, adenosine A1 receptor, etc. MCE Neuroprotective Compopund Library is a useful tool in neuroprotective drug discovery.

HY-L166

Ion Channel Compound Library

1,301 compounds

Ion channel is a membrane-binding enzyme whose catalytic site is an ion conduction pore, which is opened and closed in response to specific environmental stimuli (voltage, ligand concentration, membrane tension, temperature, etc.). Ion channel provide pores for the passive diffusion of ions on the biofilm. Due to their high selectivity for ion, ion channel are generally classified as sodium (Na⁺ ), potassium (K⁺ ), calcium (Ca²⁺ ), chloride (Cl^- ), and non-specific cation channel. Ion channel is an important contributor to cell signal transduction and homeostasis. In addition to electrical signal transduction, ion channel also have many functions: regulating vascular smooth muscle contraction, maintaining normal cell volume, regulating glandular secretion, protein kinase activation, etc. Therefore, dysfunction of ion channel can lead to many diseases, and its mechanism research is particularly important.

MCE designs a unique collection of 1,301 small molecules related to ion channel, mainly targeting Na⁺ channel, K⁺ channel, Ca²⁺ channel, GABA receptor, iGluR, etc. It is an essential tool for research of cardiovascular diseases, Nervous system diseases and other diseases.

Cat. No.	Product Name	Type

HY-D2341

6FC-GABA-Taxol

Fluorescent Dyes/Probes

6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .

Cat. No.	Product Name	Type

HY-W010078

Ethyl 4-aminobutanoate hydrochloride H-GABA-OEt·HCl	Biochemical Assay Reagents
Ethyl 4-aminobutanoate hydrochloride (H-GABA-OEt·HCl) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W002039

3-Amino-3-phenylpropionic acid DL-β-Phenylalanine	Biochemical Assay Reagents
3-Amino-3-phenylpropionic acid (DL-β-Phenylalanine) is a structural GABA analogue. 3-Amino-3-phenylpropionic acid inhibits baclofen (HY-B0007) induced gastric acid secretion .

HY-161589

GABA/KLH

Biochemical Assay Reagents

GABA/KLH is an antigen-adjuvant conjugate formed by the coupling of GABA (γ-aminobutyric acid) with keyhole limpet hemocyanin (KLH). By coupling the antigen with a protein adjuvant, it can enhance the production of antigen-specific antibodies in vaccine models. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.

HY-161588

GABA/BSA

Biochemical Assay Reagents

GABA/BSA is an antigen-adjuvant conjugate formed by the coupling of GABA (γ-aminobutyric acid) with Bovine Serum Albumin (BSA). By coupling the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.

HY-22295

*Fmoc-GABA-OH*	Biochemical Assay Reagents
Fmoc-4-aminobutanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-59302

Indole-5-carboxylic acid, 98%	Cell Assay Reagents
Indole-5-carboxylic acid, 98% is an oxytocin that interacts with serotonin receptors and gamma-aminobutyric acid (GABA) receptors. It has also been reported to interact with various enzymes such as cyclooxygenase-2 (COX-2) and 5-hydroxytryptamine (5-HT) receptors.

Cat. No.	Product Name	Target	Research Area

HY-P2602

α-Casozepine	GABA Receptor	Neurological Disease
α-Casozepine is a bioactive peptide derived from the α protein S1 casein in milk and has an affinity for γ-aminobutyric acid (GABA) receptors in the brain. α-Casozepine has anti-anxiety effects .

HY-P3280

γ-Glu-Gly	Endogenous Metabolite	Metabolic Disease
γ-Glu-Gly, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids .

HY-P1212

Cortistatin 14 (mouse, rat) CST-14 (mouse, rat)	Somatostatin Receptor	Neurological Disease
Cortistatin 14, mouse, rat (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus .

HY-P5415

*DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS*	HIV	Others
DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. (DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is also called HIV protease substrate I in some literature. It is widely used for the continuous assay for HIV protease activity. The 11-kD protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. The FRET-based fluorogenic substrate is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that is linearly related to the extent of substrate hydrolysis. The fluorescence quantum yields of the HIV-1 PR substrate in the FRET assay increased by 40.0- and 34.4-fold, respectively, per mole of substrate cleaved. Because of its simplicity and precision in the determination of reaction rates required for kinetic analysis, this substrate offers many advantages over the commonly used HPLC or electrophoresis-based assays for peptide substrate hydrolysis by retroviral PRs. Abs/Em = 340nm/490nm.)

HY-P5380

TNO211 Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2	MMP	Others
TNO211 is a biological active peptide. (Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.This peptide is a highly soluble fluorogenic MMP substrate for MMP-2, 8, 12, 13 and 14, containing the MMP cleavable Gly-Leu bond and EDANS/DABCYL. Fluorogenic assays using TNO211 are sensitive and can detect MMP activity in culture medium from endothelial cells and untreated synovial fluid from patients. Abs/Em = 340/490 nm.)

HY-P3280A

γ-Glu-Gly TFA	Endogenous Metabolite	Metabolic Disease
γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly TFA has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids .

HY-P5305A

GAD65(247-266) epitope TFA	GABA Receptor	Metabolic Disease
GAD65(247-266) epitope TFA is the T cell epitopes of islet antigens，binding to I-A ^g7 (type I diabetes-associated molecule) competitively with poor affinity. GAD65 refers to Glutamic Acid Decarboxylase 65，involved in the conversion of glutamate to gamma-aminobutyric acid (GABA) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101411

4-Acetamidobutanoic acid 1 Publications Verification N-acetyl GABA	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	GABA Receptor Endogenous Metabolite Bacterial
4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of *GABA*, exhibits antioxidant and antibacterial activities .

HY-114883A

Homocarnosine TFA 1 Publications Verification L-Homocarnosine TFA; γ-Aminobutyryl-L-histidine TFA	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	GABA Receptor Endogenous Metabolite
Homocarnosine TFA is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine TFA is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects . Homocarnosine TFA has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

HY-B1494

Picrotoxinin 3 Publications Verification	Structural Classification Natural Products other families Source classification Plants	Chloride Channel GABA Receptor
Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABA_A receptor antagonist, which negatively modulates the action of GABA on GABA_A receptors. Picrotoxinin inhibits α₁β₂γ_2L GABA_A receptor with an IC₅₀ of 1.15 μM .

HY-N0067

γ-Aminobutyric acid 3 Publications Verification 4-Aminobutyric acid	Structural Classification Animals Ketones, Aldehydes, Acids Endogenous metabolite	GABA Receptor Endogenous Metabolite
γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABA_A receptors) and metabotropic receptors (GABA_B receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system .

HY-W015878

5-Aminovaleric acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
5-Aminovaleric acid is believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak *GABA* agonist.

HY-104071

Succinaldehydic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Succinaldehydic acid is a catabolite of GABA.

HY-N9407

Guvacine ethyl ester	Alkaloids Structural Classification Classification of Application Fields Areca catechu L. Source classification Other Diseases Pyridine Alkaloids Plants Palmae Disease Research Fields	GABA Receptor
Guvacine ethyl ester (3.1b) is an alkaloid that can be found in betel nut. Guvacine ethyl ester can be used in the synthesis of GABA uptake inhibitor .

HY-114883

Homocarnosine L-Homocarnosine; γ-Aminobutyryl-L-histidine	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	GABA Receptor Endogenous Metabolite
Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects .Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .

HY-B1494R

Picrotoxinin (Standard)	Structural Classification Natural Products other families Source classification Plants	Chloride Channel GABA Receptor
Picrotoxinin (Standard) is the analytical standard of Picrotoxinin. This product is intended for research and analytical applications. Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. Picrotoxinin inhibits α1β2γ2L GABAA receptor with an IC₅₀ of 1.15 μM .

HY-N0067R

γ-Aminobutyric acid (Standard) 4-Aminobutyric acid (Standard)	Structural Classification Animals Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite GABA Receptor
γ-Aminobutyric acid (Standard) is the analytical standard of γ-Aminobutyric acid. This product is intended for research and analytical applications. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system .

HY-N9506

Anisatin	other families Terpenoids Sesquiterpenes Source classification Plants	GABA Receptor
Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive *GABA* antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC₅₀ of ~1.10 μM .

HY-B0355

Ginkgolide A 4 Publications Verification BN-52020	Structural Classification Ginkgoaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Endogenous metabolite Ginkgo biloba Inflammation/Immunology Disease Research Fields	GABA Receptor Endogenous Metabolite
Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist.

HY-B1122

L-Cycloserine 1 Publications Verification (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics Cancer	GABA Receptor HIV
L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains .

HY-N3478

Isohyenanchin Hydroxycoriatin	Structural Classification Terpenoids Sesquiterpenes Source classification Campanulaceae Campanula medium L. Plants	GABA Receptor
Isohyenanchin (Hydroxycoriatin) is an RDLac homo-oligomers antagonist. Isohyenanchin also is a weak antagonist of ionotropic GABA receptors .

HY-N1951

Miltirone 1 Publications Verification	Structural Classification Terpenoids Labiatae Samanea saman (Jacq.) Merr. Source classification Diterpenoids Plants	GABA Receptor
Miltirone is a natural compound present in the root of Salvia miltiorrhiza. Miltirone is a central benzodiazepine receptor partial agonist, with an IC₅₀ of 0.3 μM .

HY-100809

Guvacine hydrochloride	Alkaloids Structural Classification Neurological Disease Classification of Application Fields Areca catechu L. Source classification Pyridine Alkaloids Palmae Plants Disease Research Fields	GABA Receptor
Guvacine hydrochloride is an alkaloid from the nut of Areca catechu, acts as an inhibitor of GABA transporter, and dispalys modest selectivity for cloned GABA transporters with IC₅₀s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3).

HY-101414

L-DABA 1 Publications Verification L-2,4-Diaminobutyric acid	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	GABA Receptor Endogenous Metabolite
L-DABA (L-2,4-Diaminobutyric acid) is a week *GABA* transaminase inhibitor with an IC₅₀ of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.

HY-B0355R

Ginkgolide A (Standard) BN-52020 (Standard)	Structural Classification Ginkgoaceae Classification of Application Fields Terpenoids Source classification Plants Endogenous metabolite Ginkgo biloba Inflammation/Immunology Disease Research Fields	GABA Receptor Endogenous Metabolite
Ginkgolide A (Standard) is the analytical standard of Ginkgolide A. This product is intended for research and analytical applications. Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist.

HY-N9483

7-Keto-DHEA 7-Oxo-DHEA; 7-Ketodehydroepiandrosterone; 7-Oxodehydroepiandrosterone	Structural Classification Source classification Endogenous metabolite Steroids	GABA Receptor
7-Keto-DHEA binds to GABA Receptor, and reduces the ethanol intake in rats. 7-Keto-DHEA exhibits potential in investigation of alcohol dependence disorders .

HY-101414A

L-DABA hydrobromide L-2,4-Diaminobutyric acid hydrobromide	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite GABA Receptor
L-DABA (L-2,4-Diaminobutyric acid) hydrobromide is a week *GABA* transaminase inhibitor with an IC₅₀ of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.

HY-121618

α-Thujone	Infection Other Monoterpenes Platycladus orientalis (Linn.) Franco Cupressaceae Classification of Application Fields Neurological Disease Terpenoids Source classification Plants Disease Research Fields	GABA Receptor Reactive Oxygen Species Parasite Apoptosis Autophagy
α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC₅₀ for α-Thujone is 21 μM in suppressing the *GABA*-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier .

HY-N1745

2'-O-Methylisoliquiritigenin	Structural Classification Chalcones Flavonoids Leguminosae Source classification Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch. Medicago sativa L.	5-HT Receptor Dopamine Receptor GABA Receptor
2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and *GABA* pathways, but does not put a very significant effect on ne NE pathway .

HY-N2368

Arecaidine 1 Publications Verification	Alkaloids Areca catechu L. Source classification Pyridine Alkaloids Plants Palmae	GABA Receptor
Arecaidine, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine is a substrate of H ⁺-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake .

HY-N2368A

Arecaidine hydrochloride 1 Publications Verification	Alkaloids Structural Classification Areca catechu L. Source classification Pyridine Alkaloids Palmae Plants	GABA Receptor
Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H ⁺-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake .

HY-N0042

Ginsenoside Rc Panaxoside Rc	Panax ginseng C. A. Meyer Triterpenes Structural Classification Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields Araliaceae	GABA Receptor TNF Receptor Interleukin Related
Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptor_A (GABA_A)-mediated ion channel currents (I_GABA). Ginsenoside Rc inhibits the expression of TNF-α and IL-1β.

HY-P3280

γ-Glu-Gly	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Gly, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids .

HY-P3280A

γ-Glu-Gly TFA	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly TFA has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids .

HY-N2482

Guvacine	Alkaloids Structural Classification Areca catechu L. Source classification Pyridine Alkaloids Plants Palmae	GABA Receptor
Guvacine, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC₅₀ values of 39 μM, 58 μM and 378 μM, respectively .

HY-14602

Tramiprosate Homotaurine; 3-Amino-1-propanesulfonic acid	Structural Classification Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Cancer	Amyloid-β
Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects .

HY-N6776

Penitrem A	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Potassium Channel
Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals .

HY-N0662

Amentoflavone Maximum Cited Publications 9 Publications Verification Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active *GABA(A)* negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N0042R

Ginsenoside Rc (Standard)	Panax ginseng C. A. Meyer Triterpenes Structural Classification Terpenoids Source classification Plants Araliaceae	GABA Receptor TNF Receptor Interleukin Related
Ginsenoside Rc (Standard) is the analytical standard of Ginsenoside Rc. This product is intended for research and analytical applications. Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA)-mediated ion channel currents (IGABA). Ginsenoside Rc inhibits the expression of TNF-α and IL-1β.

HY-N8472

Chrodrimanin B	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	GABA Receptor
Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC₅₀?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC₅₀?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity .

HY-W028263

6-Hydroxyflavanone	Structural Classification Flavonoids Flavonones Source classification Muntingia calabura L. Plants Muntingiaceae	COX Opioid Receptor GABA Receptor Lipoxygenase
6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes .

HY-14602R

Tramiprosate (Standard)	Structural Classification Microorganisms other families Ketones, Aldehydes, Acids Source classification Plants	Amyloid-β
Tramiprosate (Standard) is the analytical standard of Tramiprosate. This product is intended for research and analytical applications. Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects .

HY-122489A

(S)-Laudanosine	Structural Classification Alkaloids Microorganisms Source classification Isoquinoline Alkaloids	Opioid Receptor GABA Receptor
(S)-Laudanosine is an alkaloid that can be found in poppies and is the S-enantiomer of Laudanosine. Laudanosine acts on the central nervous system and cardiovascular system, inhibiting low-affinity GABA receptors with an IC₅₀ value of 10 μM, and can cause seizures, hypotension, and bradycardia. Additionally, Laudanosine exerts analgesic effects by competitively binding to the opioid Mu-1 receptor (K_i = 2.7 μM) .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-B1671

(+)-Kavain	Structural Classification Source classification Other Phenylpropanoids Piper methysticum G.Forst. Piperaceae Phenylpropanoids Plants	GABA Receptor Sodium Channel Calcium Channel
(+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na ⁺ and Ca ²⁺ channels . (+)-Kavain is shown to bind at the α4β2δ GABA_A receptor and potentiate GABA efficacy . (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied .

HY-116330AR

Hyperforin dicyclohexylammonium salt (Standard)	Structural Classification Natural Products Guttiferae Source classification Hyperlcurn perforatum L. Plants	TRP Channel Calcium Channel
Hyperforin (dicyclohexylammonium salt) (Standard) is the analytical standard of Hyperforin (dicyclohexylammonium salt). This product is intended for research and analytical applications. Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin dicyclohexylammonium salt modulates γδ T cells to secret IL-17α, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model .

HY-B1671R

(+)-Kavain (Standard)	Structural Classification Source classification Other Phenylpropanoids Piper methysticum G.Forst. Piperaceae Phenylpropanoids Plants	GABA Receptor Sodium Channel Calcium Channel
(+)-Kavain (Standard) is the analytical standard of (+)-Kavain. This product is intended for research and analytical applications. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels . (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy . (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied .

HY-N7110

6-Hydroxyflavone	Structural Classification Monophenols Flavonoids Classification of Application Fields Flavones Labiatae Source classification Phenols Plants Medicago truncatula Gaertn. Inflammation/Immunology Disease Research Fields	Akt ERK JNK GABA Receptor
6-Hydroxyflavone is an orally effective flavonoid compound. 6-Hydroxyflavone can inhibit LPS (HY-D1056) -induced NO production and has anti-inflammatory effects. 6-Hydroxyflavone promotes osteoblast differentiation by activating AKT, ERK 1/2 and JNK signaling pathways. 6-Hydroxyflavone has an inhibitory effect on bovine hemoglobin (BHb) glycosylation. 6-Hydroxyflavone has a kidney protective effect. In addition, 6-Hydroxyflavone enhances GABA-induced current through the Benzodiazepine sites of γ-aminobutyric acid (GABA_A) receptors. 6-Hydroxyflavone shows a clear preference for α2 - and α3 - subtypes, which play an anti-anxiety role .

Species:	Human (10)
Tag:	His (7) SUMO (1) Strep (3) Myc (1) GST (1) MBP (1) Fc (1)
Source:	HEK293 (3) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source

HY-P72639

	GABARAP Protein, Human (His, Fc) GABA(A) Receptor-Associated Protein; GABARAP Protein; HCG1987397 Isoform CRA_b; GABARAP	Human	E. coli
	GABARAP (gamma-aminobutyric acid receptor-associated protein) is a protein that performs multiple functions within cells. As a ubiquitin-like modifier, it participates in the intracellular transport of GABA(A) receptors and interacts with the cytoskeleton. GABARAP Protein, Human (His, Fc) is the recombinant human-derived GABARAP protein, expressed by E. coli , with N-His, C-hFc labeled tag. The total length of GABARAP Protein, Human (His, Fc) is 117 a.a., with molecular weight of ~50 kDa.

HY-P70913

	GABARAPL1/GEC-1 Protein, Human (His) Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1; Early Estrogen-Regulated Protein; GABA(A) Receptor-Associated Protein-Like 1; Glandular Epithelial Cell Protein 1; GEC-1; GABARAPL1; GEC1	Human	E. coli
	GABARAPL1/GEC-1 is a multifunctional ubiquitin-like modifier that contributes to cell surface expression of kappa-type opioid receptors and contributes to autophagy, shaping autophagosome vacuoles.Unlike LC3, which is involved in phagophore elongation, the GABARAP/GATE-16 subfamily plays a crucial role in late autophagosome maturation.GABARAPL1/GEC-1 Protein, Human (His) is the recombinant human-derived GABARAPL1/GEC-1 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P72166

	DBI Protein, Human (103a.a, His) ACBD1; ACBP; ACBP_HUMAN; Acyl CoA binding domain containing 1; Acyl CoA binding protein; Acyl Coenzyme A binding domain containing 1; Acyl coenzyme A binding protein; Acyl-CoA-binding protein; CCK RP; CCKRP; Cholecystokinin releasing peptide trypsin sensitive; DBI; Diazepam-binding inhibitor; Endozepine; EP; GABA receptor modulator; MGC70414	Human	E. coli
	DBI, a versatile protein, binds medium- and long-chain acyl-CoA esters, indicating a potential intracellular carrier role. It also displaces diazepam from the benzodiazepine recognition site on the GABA type A receptor. This dual functionality suggests DBI may act as a neuropeptide, modulating GABA receptor activity. Remarkably, DBI functions as a monomer in these interactions. DBI Protein, Human (103a.a, His) is the recombinant human-derived DBI protein, expressed by E. coli , with N-6*His labeled tag. The total length of DBI Protein, Human (103a.a, His) is 103 a.a., with molecular weight of ~14 kDa.

HY-P76942

	GABARAP Protein, Human (His-MBP) GABA(A) Receptor-Associated Protein; HCG1987397 Isoform CRA_b	Human	E. coli
	GABARAP Protein is essential for regulating ubiquitination and degradation of TIAM1, a guanyl-nucleotide exchange factor (GEF) involved in RAC1 activation and downstream signaling. The D6/7 E3 ubiquitin ligase complex, where GABARAP is a key component, contributes to diverse biological processes, including cytoskeletal organization, cell migration, proliferation, and apoptosis. GABARAP Protein, Human (His-MBP) is the recombinant human-derived GABARAP protein, expressed by E. coli , with N-His, N-MBP labeled tag. The total length of GABARAP Protein, Human (His-MBP) is 117 a.a., with molecular weight of 49-58 kDa.

HY-P70861

	GABARAP Protein, Human (GST) GABA(A) Receptor-Associated Protein; GABARAP Protein; HCG1987397 Isoform CRA_b; GABARAP	Human	E. coli
	GABARAP (gamma-aminobutyric acid receptor-associated protein) is a protein that performs multiple functions within cells. As a ubiquitin-like modifier, it participates in the intracellular transport of GABA(A) receptors and interacts with the cytoskeleton. GABARAP Protein, Human (GST) is the recombinant human-derived GABARAP protein, expressed by E. coli , with N-GST labeled tag. The total length of GABARAP Protein, Human (GST) is 117 a.a., with molecular weight of ~37.0 kDa.

HY-P72068

	ABAT Protein, Human (His, SUMO, Myc) S; 3 amino 2 methylpropionate transaminase ; S; -3-amino-2-methylpropionate transaminase; 4 aminobutyrate aminotransferase; 4 aminobutyrate aminotransferase; mitochondrial; 4-aminobutyrate aminotransferase; ABAT; FLJ17813; FLJ30272; GABA aminotransferase; GABA AT; GABA T; GABA transaminase; GABA transferase; GABA-AT; GABA-T; GABAT; GABT_HUMAN; Gamma amino N butyrate transaminase; Gamma-amino-N-butyrate transaminase; hCG1984265; L AIBAT; L-AIBAT; LAIBAT; mitochondrial; NPD009	Human	E. coli
	ABAT Protein, Human (His, SUMO, Myc) is a γ-Aminobutyric acid transaminase which is responsible for GABA metabolism. ABAT, Human is implicated in mitochondrial nucleoside metabolism, respiratory capacity, membrane potential, and mitochondrial DNA maintenance.

HY-P71447

	GABRB2 Protein, Human (His) GABA(A) receptor subunit beta-2	Human	E. coli
	GABRB2 protein is an important component of heteropentameric GABA receptors that form ligand-gated chloride channels. It plays a crucial role in establishing functional inhibitory GABAergic synapses, contributing to synaptic depression. GABRB2 Protein, Human (His) is the recombinant human-derived GABRB2 protein, expressed by E. coli , with N-His labeled tag.

HY-P703132

	GABRR1 Protein, Human (HEK293, StrepⅡ) Gamma-aminobutyric acid receptor subunit rho-1; GABA(A) receptor subunit rho-1; GABAAR subunit rho-1; GABA(C) receptor; GABRR1; Homo sapiens; Human; Chloride channel; Ion channel	Human	HEK293

HY-P703130

	GABRA1-GABRB2-GABRG2 Protein, Human (HEK293, Strep) Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; GABAAR subunit alpha-1; GABRA1; Homo sapiens; Human; Chloride channel; Ion channel; Ligand-gated ion channel; Receptor	Human	HEK293

HY-P703131

	GABRA5-GABRB3 Protein, Human (HEK293, His, Strep) Gamma-aminobutyric acid receptor subunit alpha-5; GABA(A) receptor subunit alpha-5; GABAAR subunit alpha-5; GABRA5; Homo sapiens; Human; GABAAR subunit alpha-5; Chloride channel; Ion channel; Ligand-gated ion channel; Receptor;	Human	HEK293

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Cat. No.	Product Name	Chemical Structure

HY-A0057S

Gabapentin-d4
Gabapentin-d₄ is the deuterium labeled Gabapentin. Gabapentin (Neurontin) is a pharmaceutical agent, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain.

HY-101411S

4-Acetamidobutanoic acid-d3
4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of *GABA*, exhibits antioxidant and antibacterial activities .

HY-B0007S

Baclofen-d4

Baclofen-d₄ is the deuterium labeled Baclofen. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3].

HY-U00315S

Gidazepam-d5
Gidazepam-d5 is a deuterium labeled Gidazepam. Gidazepam is an agonist of GABA receptor channels (GABA RCs), and has anticonvulsant effect .

HY-A0057AS2

Gabapentin-d4 hydrochloride
Gabapentin-d4 hydrochloride is the deuterium labeled Gabapentin hydrochloride (HY-A0057A). Gabapentin hydrochloride is a potent, orally active P/Q type Ca ²⁺ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca ²⁺ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain .

HY-B0033S

Vigabatrin-13C,d2 hydrochloride

Vigabatrin- ¹³C,d₂ (hydrochloride) is the ¹³C- and deuterium labeled Vigabatrin (hydrochloride). Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase[1][2][3].

HY-B0007S2

Baclofen-d5 hydrochloride

Baclofen-d₅ hydrochloride is deuterated labeled Baclofen (HY-B0007). Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABA_B receptor (GABA_BR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABA_B receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research .

HY-139145S

Etbicyphat-13C3
Etbicyphat- ¹³C₃ is the ¹³C labeled Etbicyphat (HY-139145). Etbicyphat is a potent GABA(A) receptors competitive antagonist. Etbicyphat induces epileptiform activities in hippocampal CA1 neurons, and binds to the GABA(A)-benzodiazepine receptors[1][2].

HY-158252S

Tiagabine-d5 hydrochloride
Tiagabine-d₅ (hydrochloride) is deuterium labeled Tiagabine (hydrochloride). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-B0696AS

Tiagabine-d4 hydrochloride
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-109077S

Tigolaner-d4
Tigolaner-d₄ is deuterium labeled Tigolaner. Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent[1].

HY-17030S

Acamprosate-d3 calcium
Acamprosate-d₃ (calcium) is the deuterium labeled Acamprosate calcium. Acamprosate calcium is a GABA receptor agonist and modulator of glutamatergic systems[1][2].

HY-110233S

Acamprosate-d6 calcium
Acamprosate-d₆ (calcium) is the deuterium labeled Acamprosate calcium. Acamprosate calcium (Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems[1].

HY-B0585S1

Piracetam-d6
Piracetam-d₆ is deuterium labeled Piracetam. Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.

HY-16973S3

Fluralaner-d5
Fluralaner-d₅ (A1443-d₅) is deuterium labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of *GABA* and L-glutamate gated chloride channels .

HY-16973S

Fluralaner-13C2,15N,d3
Fluralaner- ¹³C₂, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.

HY-116152S

Cipepofol-d6
Cipepofol-d₆ (Ciprofol-d₆; HSK3486-d₆) is deuterium labeled Cipepofol (HY-116152). Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.

HY-B0585S

Piracetam-d8
Piracetam-d₈ (UCB-6215-d8) is the deuterium labeled Piracetam. Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders[1][2].

HY-B0211S

Riluzole-13C,15N2
Riluzole- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Riluzole[1]. Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM[2][3].

HY-116152S2

Cipepofol-d6-2
Cipepofol-d₆-2 (Ciprofol-d₆-2; HSK3486-d₆-2) is deuterium labeled Cipepofol (HY-116152). Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.

HY-N0067S1

γ-Aminobutyric acid-d2
γ-Aminobutyric acid-d₂ is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

HY-N0067S

γ-Aminobutyric acid-d6
γ-Aminobutyric acid-d₆ is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

HY-N0067S3

γ-Aminobutyric acid-13C4
γ-Aminobutyric acid- ¹³C₄ is the ¹³C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

HY-N0067S2

γ-Aminobutyric acid-4,4-d2
γ-Aminobutyric acid-4,4-d₂ is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

HY-14602S

Tramiprosate-d6
Tramiprosate-d₆ is the deuterium labeled Tramiprosate. Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects[1][2][3].

HY-B0822S1

Fipronil-13C6

Fipronil- ¹³C₆ is the ¹³C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.

HY-123489S

3α,21-Dihydroxy-5α-pregnan-20-one-d3
3α,21-Dihydroxy-5α-pregnan-20-one-d₃ is the deuterium labeled 3α,21-Dihydroxy-5α-pregnan-20-one. 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82673

	GABA B Receptor 1 Antibody (YA2418) GABA-B receptor 1; GABA-B-R1; GABAB R1; GABAB subunit 1c; GABABR1; GABBR1 3; Gamma aminobutyric acid (GABA) B receptor 1; Gb1; GPRC3A	WB	Human, Mouse, Rat
	GABA B Receptor 1 Antibody (YA2418) is a biotin-conjugated non-conjugated IgG antibody, targeting GABA B Receptor 1, with a predicted molecular weight of 108 kDa (observed band size: 108 kDa). GABA B Receptor 1 Antibody (YA2418) can be used for WB experiment in human, mouse, rat background.

HY-P81988

	GABA B Receptor 2 Antibody (YA1733) GABBR2; GPR51; GPRC3B; Gamma-aminobutyric acid type B receptor subunit 2; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; HG20	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	GABA B Receptor 2 Antibody (YA1733) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1733), targeting GABA B Receptor 2, with a predicted molecular weight of 106 kDa (observed band size: 106 kDa). GABA B Receptor 2 Antibody (YA1733) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

HY-P82013

	GABA A Receptor beta 2 Antibody (YA1758) GABA; GABA(A) receptor beta 2; GABA(A) receptor subunit beta-2; GABRB2	WB	Human, Mouse, Rat
	GABA A Receptor beta 2 Antibody (YA1758) is a biotin-conjugated non-conjugated IgG antibody, targeting GABA A Receptor beta 2, with a predicted molecular weight of 59 kDa (observed band size: 59 kDa). GABA A Receptor beta 2 Antibody (YA1758) can be used for WB experiment in human, mouse, rat background.

HY-P82516

	GABA A Receptor beta 1 Antibody (YA2261) GABA-A receptor; beta-1 polypeptide; Gabrb-1; GABRB1; GARB1	WB	Human, Mouse, Rat
	GABA A Receptor beta 1 Antibody (YA2261) is a biotin-conjugated non-conjugated IgG antibody, targeting GABA A Receptor beta 1, with a predicted molecular weight of 54 kDa (observed band size: 48 kDa). GABA A Receptor beta 1 Antibody (YA2261) can be used for WB experiment in human, mouse, rat background.

HY-P81570

	GABA A Receptor alpha 1 Antibody (YA1315) Gabra1, Gabra-1	WB, IHC-P	Mouse, Rat
	GABA A Receptor alpha 1 Antibody (YA1315) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1315), targeting GABA A Receptor alpha 1, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). GABA A Receptor alpha 1 Antibody (YA1315) can be used for WB, IHC-P experiment in mouse, rat background.

HY-P82050

	GABA Transporter 1 Antibody (YA1795) GABATHG; GABATR; GABT1; GAT1; Slc6a1	WB	Human, Mouse, Rat
	GABA Transporter 1 Antibody (YA1795) is a biotin-conjugated non-conjugated IgG antibody, targeting GABA Transporter 1, with a predicted molecular weight of 67 kDa (observed band size: 67 kDa). GABA Transporter 1 Antibody (YA1795) can be used for WB experiment in human, mouse, rat background.

HY-P82504

	GABA A Receptor alpha 5 Antibody (YA2249) GAA 5; GAA5; GABRA 5; Gabra5	WB, ICC/IF	Human, Mouse, Rat
	GABA A Receptor alpha 5 Antibody (YA2249) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2249), targeting GABA A Receptor alpha 5, with a predicted molecular weight of 52 kDa (observed band size: 70 kDa). GABA A Receptor alpha 5 Antibody (YA2249) can be used for WB, ICC/IF experiment in human, mouse, rat background.

HY-P82219

	ABAT Antibody (YA1964) ABAT; GABA transaminase; GABA transferase; GABAT; LAIBAT	WB, IP	Rat
	ABAT Antibody (YA1964) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1964), targeting ABAT, with a predicted molecular weight of 56 kDa (observed band size: 56 kDa). ABAT Antibody (YA1964) can be used for WB, IP experiment in rat background.

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Cat. No.	Product Name		Classification

HY-131693A

*γ-Acetylenic GABA* hydrochloride** GAG hydrochloride		Alkynes
γ-Acetylenic GABA (GAG) hydrochloride is an irreversible inhibitor of *GABA-transaminase. γ-Acetylenic GABA* hydrochloride can increase the concentration of GABA in rat brain . γ-Acetylenic GABA (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-131693

γ-Acetylenic GABA GAG		Alkynes
γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is an irreversible inhibitor of *GABA-transaminase. γ-Acetylenic GABA* can increase the concentration of GABA in rat brain . γ-Acetylenic GABA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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