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CD206<sup> </sup>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (1) 5-HT Receptor (1) Adrenergic Receptor (3) Amino Acid Derivatives (2) Amyloid-β (2) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (2) Antibiotic (28) Apical Sodium-Dependent Bile Acid Transporter (1) Apoptosis (52) Autophagy (42) Bacterial (46) Bcl-2 Family (1) Beta-lactamase (1) Biochemical Assay Reagents (6) Calcium Channel (16) Carbonic Anhydrase (2) Cathepsin (1) CGRP Receptor (1) COX (8) Disulfidptosis (1) DNA Methyltransferase (1) DNA/RNA Synthesis (48) Dopamine Receptor (1) Drug Metabolite (4) Dynamin (1) E1/E2/E3 Enzyme (1) EAAT (1) EGFR (2) Endogenous Metabolite (386) Epigenetic Reader Domain (1) Estrogen Receptor/ERR (7) Ferroptosis (15) Flavivirus (1) Fluorescent Dye (3) Fungal (3) FXR (2) G protein-coupled Bile Acid Receptor 1 (2) GABA Receptor (5) Gap Junction Protein (1) Glutathione Reductase (1) GlyT (1) HBV (1) HCV (1) HDAC (1) Hexokinase (3) HIF/HIF Prolyl-Hydroxylase (6) Histamine Receptor (1) Histone Acetyltransferase (2) Histone Demethylase (2) HIV (8) HIV Protease (1) HPV (2) HSV (9) iGluR (9) IKK (2) Imidazoline Receptor (1) Influenza Virus (11) Interleukin Related (2) Isotope-Labeled Compounds (491) JAK (1) Keap1-Nrf2 (2) Ligands for E3 Ligase (2) Liposome (2) Lipoxygenase (2) mAChR (1) mGluR (10) Microtubule/Tubulin (1) Mitochondrial Metabolism (2) Mitophagy (5) Molecular Glues (3) Monoamine Oxidase (1) Na+/K+ ATPase (2) nAChR (1) Neprilysin (2) NF-κB (6) NO Synthase (9) Nucleoside Antimetabolite/Analog (41) Opioid Receptor (1) Organoid (1) Orthopoxvirus (8) Oxidative Phosphorylation (1) P-glycoprotein (2) P2Y Receptor (3) PAK (2) Parasite (12) PARP (1) Potassium Channel (6) PPAR (2) Progesterone Receptor (4) Prostaglandin Receptor (1) PROTAC Linkers (2) RAD51 (2) RAR/RXR (1) Reactive Oxygen Species (24) RSV (1) SARS-CoV (5) Ser/Thr Protease (1) SGLT (1) Sirtuin (3) Sodium Channel (8) STAT (2) STING (2) TGF-beta/Smad (1) Thrombin (2) Thrombopoietin Receptor (2) Thymidylate Synthase (1) Thyroid Hormone Receptor (3) Topoisomerase (1) TRP Channel (1) Tyrosinase (2) VD/VDR (2) VEGFR (2) Virus Protease (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (180) Cardiovascular Disease (31) Endocrinology (19) Infection (73) Inflammation/Immunology (59) Metabolic Disease (174) Neurological Disease (72)
Click Chemistry:	Labeling and Fluorescence Imaging (2) Azide (1) Tetrazine (1) Alkynes (4)

731

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

696

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148591

GSK761	Epigenetic Reader Domain	Inflammation/Immunology
GSK761 is a selective inhibitor of speckled 140 kDa (SP140) with an IC₅₀ value of 77.79 nM. GSK761 reduces monocyte-to-inflammatory macrophage differentiation and lipopolysaccharide (LPS)-induced inflammatory activation. GSK761 induces the production of CD206 ⁺ regulatory macrophages by inhibiting SP140 .

HY-160421

TREM2-IN-1	Apoptosis	Inflammation/Immunology Cancer
TREM2-IN-1 (OPA) is a TREM2 inhibitor derived from oxaliplatin and artesunate. TREM2-IN-1 can relieves immunosuppressive tumor microenvironment and enhancing chemical anticancer efficiency. TREM2-IN-1 deters the tumor growth in mice models bearing MC38 colorectal tumor by reducing the number of CD206 ⁺ and CX₃CR1 ⁺ immunosuppressive macrophages. TREM2-IN-1 also promotes the expansion and infiltration of immunostimulatory dendritic, cytotoxic T and natural killer cells .

HY-15306S

Eltrombopag-13C4 1 Publications Verification SB-497115-<sup>13sup>C₄	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-126906

Milbemycin A4	Antibiotic P-glycoprotein	Cancer
Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity ^[1]sup>[2].

HY-W011509

CyPPA	Potassium Channel	Neurological Disease
CyPPA is a positive modulator of hSK3 and hSK2, with EC₅₀ values of 14 μM and 5.6 μM, repectively. CyPPA is inactive on both hSK1 and hIK channels ^{[1]sup .}

HY-169089

RP-182-PEG3-K(palmitic acid)	Others	Cancer
RP-182-PEG3-K palmitic acid (Compound 1a) inhibits CD206 ^high M2-like macrophage (IC₅₀ of 3.2 µM) and induces phagocytosis. RP-182-PEG3-K palmitic acid exhibits antitumor efficacy in mouse B16 melanoma allografts .

HY-N12231

Carbazomycin B	Antibiotic Bacterial Lipoxygenase	Infection Cancer
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC₅₀ Of 1.5 µM ^[1]sup>[2]sup>[3]sup>[4].

HY-157926

Nitroso-PSAP	Biochemical Assay Reagents	Others
Nitroso-PSAP is a sensitive and specific chromogenic reagent for iron (Fe ²⁺), which is used for the colorimetric determination of iron in blood after mineralization with periodic acid. TNitroso-PSAP chelates with iron (Fe ²⁺) to produce a green complex (λmax=756 nm, Epsilon = 4.5 x 10 < sup > 4 < / sup > dm < sup > 3 < / sup > mol < sup > 1 < / sup > cm < sup > 1 < / sup >) .

HY-108166

Hydroxystilbamidine	Fluorescent Dye	Inflammation/Immunology
Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain ^{[1]sup .}

HY-145128

GR103545	Opioid Receptor	Neurological Disease
GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). ¹¹GR103545 is a radiotracer for imaging κ-OR in vivo ^{[1]sup .}

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Others	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-161119

Drpitor1a	Dynamin Reactive Oxygen Species	Cardiovascular Disease Cancer
Drpitor1a is a potent Drp1 inhibitor. Drpitor1a inhibits mitochondrial ROS production, preventes mitochondrial fission, and improves right ventricular diastolic dysfunction during IR (ischemia reperfusion) injury. Drpitor1a has the potential for the research of lung cancer ^{[1]sup .}

HY-126906R

Milbemycin A4 (Standard)	Antibiotic P-glycoprotein	Cancer
Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity ^[1]sup> .

HY-12741

LDN-212320 Maximum Cited Publications 6 Publications Verification LDN-0212320; OSU-0212320	EAAT	Neurological Disease
LDN-212320 (LDN-0212320) is a glutamate transporter (GLT-1)/excitatory amino acid transporter 2 (EAAT2) activator (at translational level). LDN-212320 (LDN-0212320) prevents nociceptive pain by upregulating astroglial GLT-1 expression in the hippocampus and ACC ^{[1]sup .}

HY-N8824

Maackiaflavanone	Others	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-Y0850U

PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) (Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)) is a biocompatible, biodegradable, nontoxic and hydrophilic synthetic polymer. PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) can be used to produce bone tissue engineering scaffold ^{[1]sup .}

HY-P4583

Suc-Val-Pro-Phe-SBzl	Cathepsin	Others
Suc-Val-Pro-Phe-SBzl (succinyl-valine-proline-phenylalanine thiobenzyl ester) is an inhibitor of CatG enzymes with IC₅₀ values of 111-225 mM.

HY-N3872

Ethyl β-D-glucopyranoside	Others	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-D1583

Cyanine5 DBCO 1 Publications Verification DBCO-Cy5; Cyanine5 dibenzocyclooctyne	Fluorescent Dye	Others
Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) ^[2].

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Others	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-156383

SCO-PEG3-NHS	PROTAC Linkers	Cancer
SCO-PEG3-NHS is a PEG linker with a terminal imine(NH) group. SCO-PEG3-NHS is a PEG-based PROTAC linker can be used in the synthesis of *PROTACs*.

HY-N0733S2

Glucosamine-13C,15N hydrochloride D-(+)-Glucosamine-<sup>13sup>C,<sup>15sup>N hydrochloride; Chitosamine-<sup>13sup>C,<sup>15sup>N hydrochloride	Isotope-Labeled Compounds Autophagy Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species	Inflammation/Immunology Cancer
Glucosamine- ¹³C, ¹⁵N (hydrochloride) is the ¹³C and ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i

HY-B0271S1

Pyrazinamide-13C,15N Pyrazinecarboxamide-<sup>13sup>C,<sup>15sup>N; Pyrazinoic acid amide-<sup>13sup>C,<sup>15sup>N	Autophagy Antibiotic Bacterial Isotope-Labeled Compounds	Infection
Pyrazinamide- ¹³C, ¹⁵N is ¹⁵N and ¹³C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.

HY-N0650S6

L-Serine1-13C,15N (-)-Serine-<sup>13sup>C,<sup>15sup>N; (S)-Serine-<sup>13sup>C,<sup>15sup>N	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
L-Serine1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-D1327

Cyanine3 azide chloride	Fluorescent Dye	Others
Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λ_ex=684 nm, λ_em=710 nm) ^{[1]sup >. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.}

HY-Y0418S

Dulcite-13C Dulcitol-<sup>13sup>C; Melampyrit-<sup>13sup>C; NSC 1944-<sup>13sup>C	Isotope-Labeled Compounds Endogenous Metabolite	Others
Dulcite- ¹³C is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-13771S1

Ursodeoxycholic acid-13C Ursodeoxycholate-<sup>13sup>C; Ursodiol-<sup>13sup>C; UDCA-<sup>13sup>C	Isotope-Labeled Compounds G protein-coupled Bile Acid Receptor 1 FXR Endogenous Metabolite	Cancer
Ursodeoxycholic acid- ¹³C is the ¹³C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].

HY-A0061S

Trifluridine-13C,15N2 Trifluorothymidine-<sup>13sup>C,<sup>15sup>N₂; 5-Trifluorothymidine-<sup>13sup>C,<sup>15sup>N₂; TFT-<sup>13sup>C,<sup>15sup>N₂	Thymidylate Synthase Nucleoside Antimetabolite/Analog HSV Orthopoxvirus	Cancer
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].

HY-B0389S10

D-Glucose-13C Glucose-<sup>13sup>C; D-(+)-Glucose-<sup>13sup>C; Dextrose-<sup>13sup>C	Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S29

D-Glucose-18O Glucose-<sup>18sup>O; D-(+)-Glucose-<sup>18sup>O; Dextrose-<sup>18sup>O	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose- ¹⁸O is the ¹⁸O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules

HY-13458S1

Droxidopa-13C2,15N hydrochloride L-DOPS-<sup>13sup>C₂,<sup>15sup>N hydrochloride; DOPS-<sup>13sup>C₂,<sup>15sup>N hydrochloride; SM5688-<sup>13sup>C₂,<sup>15sup>N hydrochloride	Adrenergic Receptor Isotope-Labeled Compounds	Neurological Disease
Droxidopa- ¹³C₂, ¹⁵N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier[1][2].

HY-66005S4

Acetaminophen-13C2,15N Paracetamol-<sup>13sup>C₂,<sup>15sup>N; 4-Acetamidophenol-<sup>13sup>C₂,<sup>15sup>N; 4'-Hydroxyacetanilide-<sup>13sup>C₂,<sup>15sup>N	COX Bacterial Histone Acetyltransferase Parasite Endogenous Metabolite	Inflammation/Immunology
Acetaminophen- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].

HY-N1480S

(-)-Fucose-13C 6-Desoxygalactose-<sup>13sup>C; L-(-)-Fucose-<sup>13sup>C; L-Galactomethylose-<sup>13sup>C	Isotope-Labeled Compounds Endogenous Metabolite Parasite	Infection Metabolic Disease
(-)-Fucose- ¹³C is the ¹³C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[1]

HY-Y1250S6

Fmoc-Gly-OH-13C2,15N Fmoc glycine-<sup>13sup>C₂,<sup>15sup>N; N-(9-Fluorenylmethoxycarbonyl)glycine-<sup>13sup>C₂,<sup>15sup>N; N-Fluorenylmethoxycarbonylglycine-<sup>13sup>C₂,<sup>15sup>N; NPC 14692-<sup>13sup>C₂-<sup>15sup>N; NSC 334288-<sup>13sup>C₂,<sup>15sup>N; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid-<sup>13sup>C₂,<sup>15sup>N	Isotope-Labeled Compounds Influenza Virus Bacterial	Infection
Fmoc-Gly-OH- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.

HY-Z0283S

Benzamide-15N Benzenecarboxamide-<sup>15sup>N; Phenylamide-<sup>15sup>N	Endogenous Metabolite PARP	Others
Benzamide- ¹⁵N is a ¹⁵N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].

HY-W067028S

Semicarbazide-13C,15N2 hydrochloride Aminourea-<sup>13sup>C,<sup>15sup>N₂ hydrochloride; Hydrazinecarboxamide-<sup>13sup>C,<sup>15sup>N₂ hydrochloride	Isotope-Labeled Compounds	Others
Semicarbazide- ¹³C, ¹⁵N₂ hydrochloride is ¹⁵N and ¹³C labeled Semicarbazide.

HY-B0215S1

Acetylcysteine-15N N-Acetylcysteine-<sup>15sup>N; N-Acetyl-L-cysteine-<sup>15sup>N; NAC-<sup>15sup>N	Isotope-Labeled Compounds Reactive Oxygen Species Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis	Infection Neurological Disease
Acetylcysteine- ¹⁵N (N-Acetylcysteine- ¹⁵N) is the ¹⁵N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .

HY-Y0504S2

Trimethylammonium chloride-15N Hegzadesil-<sup>15sup>N; Trimethylamine hydrochloric acid-<sup>15sup>N; Trimethylamine monohydrochloride-<sup>15sup>N	Endogenous Metabolite	Metabolic Disease
Trimethylammonium chloride- ¹⁵N is the ¹⁵N labeled Trimethylammonium chloride[1]. Trimethylammonium chloride is an endogenous metabolite.

HY-W654136

2'-Deoxycytidine-2'-13C Deoxycytidine-<sup>13sup>C; Cytosine deoxyriboside-<sup>13sup>C; Deoxyribose cytidine-<sup>13sup>C	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2'-Deoxycytidine-2'- ¹³C is ¹³C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer .

HY-A0070AS1

Liothyronine-13C9,15N Triiodothyronine-<sup>13sup>C₉,<sup>15sup>N; 3,3',5-Triiodo-L-thyronine-<sup>13sup>C₉,<sup>15sup>N; T3-<sup>13sup>C₉,<sup>15sup>N	Thyroid Hormone Receptor Endogenous Metabolite	Cancer
Liothyronine- ¹³C₉, ¹⁵N is the ¹³C and ¹⁵N labeled Liothyronine[1]. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[2][3][4].

HY-B0150S1

Nicotinamide-15N,13C3 Niacinamide-<sup>15sup>N,<sup>13sup>C₃; Nicotinic acid amide-<sup>15sup>N,<sup>13sup>C₃	Endogenous Metabolite Sirtuin	Neurological Disease Cancer
Nicotinamide- ¹⁵N, ¹³C₃ is the ¹³C-labeled and ¹⁵N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

HY-N0733S5

Glucosamine-13C6,15N hydrochloride D-(+)-Glucosamine-<sup>13sup>C₆,<sup>15sup>N hydrochloride; Chitosamine-<sup>13sup>C₆,<sup>15sup>N hydrochloride	Isotope-Labeled Compounds Autophagy Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species	Inflammation/Immunology Cancer
Glucosamine- ¹³C₆, ¹⁵N (hydrochloride) is the ¹³C and ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids,

HY-13417S

AICAR-13C2,15N Acadesine-<sup>13sup>C₂,<sup>15sup>N; AICA Riboside-<sup>13sup>C₂,<sup>15sup>N	Isotope-Labeled Compounds	Others
AICAR- ¹³C₂, ¹⁵N (Acadesine- ¹³C₂, ¹⁵N; AICA Riboside- ¹³C₂, ¹⁵N)is the ¹³C and ¹⁵N labeledAICAR(HY-13417) . AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor .

HY-W778058

Guanosine-13C,15N2 DL-Guanosine-<sup>13sup>C,<sup>15sup>N₂; Vernine-<sup>13sup>C,<sup>15sup>N₂	Isotope-Labeled Compounds	Others
Guanosine- ¹³C, ¹⁵N₂ (DL-Guanosine- ¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Guanosine .

HY-Y0842S

Formamide-13C Methanamide-<sup>13sup>C; Formimidic acid-<sup>13sup>C	Isotope-Labeled Compounds Endogenous Metabolite	Others
Formamide- ¹³C is the ¹³C-labeled Formamide. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.

HY-101037S

Sarcosine-15N N-Methylglycine-<sup>15sup>N; Sarcosin-<sup>15sup>N	Endogenous Metabolite GlyT	Cancer
Sarcosine- ¹⁵N is the ¹⁵N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

HY-N0623S1

L-Tryptophan-13C Tryptophan-<sup>13sup>C; Tryptophane-<sup>13sup>C	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S7

L-Tryptophan-15N Tryptophan-<sup>15sup>N; Tryptophane-<sup>15sup>N	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0378S1

D-Mannitol-13C Mannitol-<sup>13sup>C; Mannite-<sup>13sup>C	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite	Metabolic Disease Cancer
D-Mannitol- ¹³C is the ¹³C labeled D-Mannitol[1][2][3][4].

HY-N0733S

Glucosamine-13C hydrochloride D-(+)-Glucosamine-<sup>13sup>C hydrochloride; Chitosamine-<sup>13sup>C hydrochloride	Isotope-Labeled Compounds Autophagy Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species	Inflammation/Immunology Cancer
Glucosamine- ¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

Cat. No.	Product Name	Type

HY-D1583

Cyanine5 DBCO

1 Publications Verification

DBCO-Cy5; Cyanine5 dibenzocyclooctyne

Fluorescent Dyes/Probes

Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) ^[2].

HY-D1327

Cyanine3 azide chloride

Fluorescent Dyes/Probes

Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λ_ex=684 nm, λ_em=710 nm) ^{[1]sup >. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.}

Cat. No.	Product Name	Type

HY-157926

Nitroso-PSAP	Chelators
Nitroso-PSAP is a sensitive and specific chromogenic reagent for iron (Fe ²⁺), which is used for the colorimetric determination of iron in blood after mineralization with periodic acid. TNitroso-PSAP chelates with iron (Fe ²⁺) to produce a green complex (λmax=756 nm, Epsilon = 4.5 x 10 < sup > 4 < / sup > dm < sup > 3 < / sup > mol < sup > 1 < / sup > cm < sup > 1 < / sup >) .

HY-Y0850U

PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)

Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)

Drug Delivery

PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) (Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)) is a biocompatible, biodegradable, nontoxic and hydrophilic synthetic polymer. PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) can be used to produce bone tissue engineering scaffold ^{[1]sup .}

Cat. No.	Product Name	Target	Research Area

HY-P0090S

Calcitonin-13C6,15N4 (salmon) TFA Salmon calcitonin-<sup>13sup>C₆,<sup>15sup>N₄ TFA	CGRP Receptor	Metabolic Disease
Calcitonin- ¹³CIC₆, ¹⁵NIC₄ (salmon) (Salmon calcitonin- ¹³CIC₆, ¹⁵NIC₄) TFA is ¹³C and ¹⁵N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .

HY-P1604A

ATX-II TFA	Sodium Channel	Inflammation/Immunology
ATX-II TFA is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II TFA causes delayed inactivation of the Na ^{+sup channel in cell cultures. ATX-II TFA sensitizes skeletal muscle to Halothane (HY-B1010), Caffeine, and Ryanodine (HY-103306). ATX-II TFA also induces pulmonary vein arrhythmogenesis and atrial fibrillation .}

HY-P4583

Suc-Val-Pro-Phe-SBzl	Cathepsin	Others
Suc-Val-Pro-Phe-SBzl (succinyl-valine-proline-phenylalanine thiobenzyl ester) is an inhibitor of CatG enzymes with IC₅₀ values of 111-225 mM.

HY-P1604

ATX-II	Sodium Channel	Inflammation/Immunology
ATX-II is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na ^{+sup channel in cell cultures. ATX-II sensitizes skeletal muscle to Halothane (HY-B1010), Caffeine, and Ryanodine (HY-103306). ATX-II also induces pulmonary vein arrhythmogenesis and atrial fibrillation .}

HY-P10324

TAT-p16 p16<sup>INK4asup> peptide	Peptides	Cancer
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .

HY-P0265AS

β-Amyloid-15N (1-40) TFA Amyloid Beta-Peptide-<sup>15sup>N (1-40) (human) TFA; Amyloid β-Peptide-<sup>15sup>N (1-40) (human) TFA	Amyloid-β	Neurological Disease
β-Amyloid- ¹⁵N (1-40) (TFA) is the ¹⁵N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease[1].

HY-P5340

Amyloid-Forming peptide GNNQQNY	Peptides	Others
Amyloid-Forming peptide GNNQQNY is a biological active peptide. (This is a heptapeptide from the N-terminal prion-determining domain of the yeast protein Sup35 that forms amyloid fibrils. The availability of its detailed atomic oligomeric structure makes it a good model for studying the early stage of aggregation. The GNNQQNY dimer forms three stable sheet structures. in-register parallel, off-register parallel, and anti-parallel. The in-register parallel dimer, which is close to the amyloid beta-sheet structure, has few interpeptide hydrogen bonds, making hydrophobic interactions more important and increasing the conformational entropy compared to the anti-parallel sheet.)

HY-P1363S

β-Amyloid-15N (1-42), human TFA Amyloid β-peptide-<sup>15sup>N (1-42) (human) TFA	Amyloid-β	Neurological Disease
β-Amyloid- ¹⁵N (1-42), human (TFA) is the ¹⁵N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3872

Ethyl β-D-glucopyranoside	Scabiosa stellata L. Structural Classification Natural Products Caprifoliaceae Source classification Plants	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-N3980

Guaiol Champacol; Guaiac alcohol	Infection Structural Classification Natural Products Classification of Application Fields Source classification Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields	Autophagy RAD51
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC₅₀ of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^{[4]sup .}

HY-N12231

Carbazomycin B	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Bacterial Lipoxygenase
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC₅₀ Of 1.5 µM ^[1]sup>[2]sup>[3]sup>[4].

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Structural Classification Natural Products Rhodiola rosea Linn. Source classification Crassulaceae Plants	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-N8824

Maackiaflavanone	Structural Classification Flavonoids Leguminosae Flavonones Source classification Maackia amurensis Rupr. et Maxim. Plants	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Structural Classification Natural Products Source classification Lridaceae Plants	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-N8930

Eupatorin-5-methyl ether	Structural Classification Galinsoga parviflora Cav. Flavonoids Flavones Labiatae Source classification Plants	Others
Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

HY-N3980R

Guaiol (Standard)	Structural Classification Natural Products Source classification Distemonanthus benthamianus Baill. Plants Compositae	Autophagy RAD51
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[3][4] .

Species:	Human (4) Mouse (1)
Tag:	His (3) Tag Free (1) GST (1)
Source:	HEK293 (2) Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P78736

	CD206/MMR Protein, Human (HEK293, His) MMR; CD206; hMR; MRC1; CLEC13D; CLEC13DL; MRC1L1	Human	HEK293
	The CD206/MMR protein acts as a multifunctional mediator in macrophages, promoting glycoprotein internalization. It has a broad binding capacity, interacting with both sulfated and non-sulfated polysaccharide chains. CD206/MMR Protein, Human (HEK293, His) is the recombinant human-derived CD206/MMR protein, expressed by HEK293 , with C-His labeled tag.

HY-P702528

	CD206/MMR Protein, Mouse (HEK293, His) CD206; CLEC13D; CLEC13Dmacrophage mannose receptor 1; C-type lectin domain family 13 member D; mannose receptor, C type 1; MMR; MMRCD206 antigen; MRC1	Mouse	HEK293
	The CD206/MMR protein acts as a multifunctional mediator in macrophages, promoting glycoprotein internalization. It has a broad binding capacity, interacting with both sulfated and non-sulfated polysaccharide chains. CD206/MMR Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD206/MMR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD206/MMR Protein, Mouse (HEK293, His) is 1370 a.a..

HY-P73634

	SNAP25 Protein, Human (His) Synaptosomal-associated protein 25; SNAP-25; sup; SNAP	Human	E. coli
	SNAP25 is a key t-SNARE in neurotransmitter release, regulating synaptic function and plasma membrane recycling. It cooperates with CENPF to affect vesicle docking and membrane fusion. SNAP25 Protein, Human (His) is the recombinant human-derived SNAP25 protein, expressed by E. coli , with N-His labeled tag. The total length of SNAP25 Protein, Human (His) is 206 a.a., with molecular weight of ~28 kDa.

HY-P703566

	ETF1 Protein, Human ERF1; RF1; sup45L1	Human	E. coli
	ETF1 Protein, Human is the recombinant human-derived ETF1, expressed by E. coli , with tag Free labeled tag. The total length of ETF1 Protein, Human is 135 a.a.,

HY-P702942

	ERF1 protein, Human (sf9, GST) ERF1; RF1; sup45L1	Human	Sf9 insect cells
	ERF1 protein, Human (sf9, GST) is the recombinant human-derived ERF1, expressed by Sf9 insect cells , with GST labeled tag. The total length of ERF1 protein, Human (sf9, GST) is 436 a.a.,

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Cat. No.	Product Name	Chemical Structure

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-B0389S10

D-Glucose-13C
D-Glucose- ¹³C is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-N0733S2

Glucosamine-13C,15N hydrochloride
Glucosamine- ¹³C, ¹⁵N (hydrochloride) is the ¹³C and ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i

HY-B0271S1

Pyrazinamide-13C,15N
Pyrazinamide- ¹³C, ¹⁵N is ¹⁵N and ¹³C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.

HY-N0650S6

L-Serine1-13C,15N
L-Serine1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-Y0418S

Dulcite-13C
Dulcite- ¹³C is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-13771S1

Ursodeoxycholic acid-13C

Ursodeoxycholic acid- ¹³C is the ¹³C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].

HY-A0061S

Trifluridine-13C,15N2
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].

HY-B0389S29

D-Glucose-18O
D-Glucose- ¹⁸O is the ¹⁸O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules

HY-13458S1

Droxidopa-13C2,15N hydrochloride
Droxidopa- ¹³C₂, ¹⁵N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier[1][2].

HY-66005S4

Acetaminophen-13C2,15N
Acetaminophen- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].

HY-N1480S

(-)-Fucose-13C
(-)-Fucose- ¹³C is the ¹³C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[1]

HY-Y1250S6

Fmoc-Gly-OH-13C2,15N
Fmoc-Gly-OH- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.

HY-Z0283S

Benzamide-15N
Benzamide- ¹⁵N is a ¹⁵N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].

HY-W067028S

Semicarbazide-13C,15N2 hydrochloride
Semicarbazide- ¹³C, ¹⁵N₂ hydrochloride is ¹⁵N and ¹³C labeled Semicarbazide.

HY-B0215S1

Acetylcysteine-15N

Acetylcysteine- ¹⁵N (N-Acetylcysteine- ¹⁵N) is the ¹⁵N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .

HY-Y0504S2

Trimethylammonium chloride-15N
Trimethylammonium chloride- ¹⁵N is the ¹⁵N labeled Trimethylammonium chloride[1]. Trimethylammonium chloride is an endogenous metabolite.

HY-W654136

2'-Deoxycytidine-2'-13C
2'-Deoxycytidine-2'- ¹³C is ¹³C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer .

HY-A0070AS1

Liothyronine-13C9,15N
Liothyronine- ¹³C₉, ¹⁵N is the ¹³C and ¹⁵N labeled Liothyronine[1]. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[2][3][4].

HY-B0150S1

Nicotinamide-15N,13C3
Nicotinamide- ¹⁵N, ¹³C₃ is the ¹³C-labeled and ¹⁵N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

HY-N0733S5

Glucosamine-13C6,15N hydrochloride
Glucosamine- ¹³C₆, ¹⁵N (hydrochloride) is the ¹³C and ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids,

HY-13417S

AICAR-13C2,15N
AICAR- ¹³C₂, ¹⁵N (Acadesine- ¹³C₂, ¹⁵N; AICA Riboside- ¹³C₂, ¹⁵N)is the ¹³C and ¹⁵N labeledAICAR(HY-13417) . AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor .

HY-W778058

Guanosine-13C,15N2
Guanosine- ¹³C, ¹⁵N₂ (DL-Guanosine- ¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Guanosine .

HY-Y0842S

Formamide-13C
Formamide- ¹³C is the ¹³C-labeled Formamide. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.

HY-101037S

Sarcosine-15N
Sarcosine- ¹⁵N is the ¹⁵N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

HY-N0623S1

L-Tryptophan-13C
L-Tryptophan- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S7

L-Tryptophan-15N
L-Tryptophan- ¹⁵N is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0378S1

D-Mannitol-13C
D-Mannitol- ¹³C is the ¹³C labeled D-Mannitol[1][2][3][4].

HY-N0733S

Glucosamine-13C hydrochloride
Glucosamine- ¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

HY-N1150S2

Thymidine-13C
Thymidine- ¹³C is the ¹³C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]

HY-N0733S4

Glucosamine-15N hydrochloride
Glucosamine- ¹⁵N (hydrochloride) is the ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

HY-W779296

Potassium thiocyanate-13C,15N
Potassium thiocyanate- ¹³C, ¹⁵N (Potassium rhodanide- ¹³C, ¹⁵N) is ¹³C and ¹⁵N labeled Potassium thiocyanate .

HY-N0667S4

L-Asparagine-4-13C monohydrate
L-Asparagine-4- ¹³C (monohydrate) is the ¹³C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-Y0418S1

Dulcite-13C-1
Dulcite- ¹³C-1 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-Y0418S2

Dulcite-13C-2
Dulcite- ¹³C-2 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-Y0418S3

Dulcite-13C-3
Dulcite- ¹³C-3 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-B0617S1

S-Adenosyl-L-methionine-13C

S-Adenosyl-L-methionine- ¹³C is the ¹³C labeled S-Adenosyl-L-methionine[1]. S-Adenosyl-L-methionine (S-Adenosyl methionine) is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects, and has the potential for liver disease and osteoarthritis research[2][3][4].

HY-B0178AS

Guanidine-13C,15N3 hydrochloride
Guanidine- ¹³C, ¹⁵N₃ (hydrochloride)is the ¹³C-labeled and ¹⁵N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[1][2].

HY-N0650S5

L-Serine-13C3,15N
L-Serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-13677S1

6-Mercaptopurine-13C2,15N
6-Mercaptopurine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.

HY-N0091S1

Hypoxanthine-13C,15N2
Hypoxanthine- ¹³C, ¹⁵N₂ is a ¹⁵N-labeled and ¹³C-labled Furaltadone. Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci

HY-N0091S3

Hypoxanthine-13C2,15N
Hypoxanthine- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled DL-Cystine[1].

HY-13623S1

Entecavir-13C2,15N
Entecavir- ¹³C₂, ¹⁵N (BMS200475- ¹³C₂, ¹⁵N; SQ34676- ¹³C₂, ¹⁵N) is a ¹³C- and ¹⁵N-labeled Entecavir (HY-13623). Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC₅₀ of 3.75 nM in HepG2 cell.

HY-14164S1

Zileuton-13C2,15N
Zileuton- ¹³C₂, ¹⁵N is ¹⁵N and ¹³C labeled Zileuton (HY-14164). Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.

HY-B0136S

Cefdinir-13C,15N2

Cefdinir- ¹³C, ¹⁵N₂ (FK-482- ¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-N0545S

Taurocholic acid-13C2,15N sodium
Taurocholic acid- ¹³C₂, ¹⁵N (sodium) is the ¹³C- and ¹⁵N- labeled Taurocholic acid (sodium).

HY-14291S2

Vildagliptin-13C5,15N
Vildagliptin- ¹³C₅, ¹⁵N (LAF237- ¹³C₅, ¹⁵N; NVP-LAF 237- ¹³C₅, ¹⁵N) is a ¹³C- and ¹⁵N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-B0389S11

D-Glucose-13C-1
D-Glucose- ¹³C-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S12

D-Glucose-13C-2
D-Glucose- ¹³C-2 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S16

D-Glucose-13C-4
D-Glucose- ¹³C-4 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81214

	MRC1 Antibody Mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_HUMAN; Macrophage mannose receptor 1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1.	WB	Human, Rat
	MRC1 Antibody is an unconjugated, approximately 160 kDa, rabbit-derived, anti-MRC1 monoclonal antibody. MRC1 Antibody can be used for: WB expriments in human and rat background without labeling.

HY-P83714M

	*Rat Anti-Mouse CD206* Antibody (APC)** MMR; MR; MRC1; macrophage mannose receptor; mannose receptor	FC	Mouse

HY-P81667

	SNAP25 Antibody (YA1412) Synaptosomal-associated protein 25; SNAP-25; super protein; sup; Synaptosomal-associated 25 kDa protein; SNAP25; SNAP	WB, ICC/IF, IP	Human, Mouse, Rat
	SNAP25 Antibody (YA1412) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1412), targeting SNAP25, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). SNAP25 Antibody (YA1412) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-D1327

Cyanine3 azide chloride		Azide Labeling and Fluorescence Imaging
Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λ_ex=684 nm, λ_em=710 nm) ^{[1]sup >. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.}

HY-156497

Biotin-PEG8-Me-Tet		Tetrazine Labeling and Fluorescence Imaging
Biotin-PEG8-Me-Tet is a biotin labeling.

HY-50896S1

Erlotinib-13C6 CP-358774-<sup>13sup>C₆; NSC 718781-<sup>13sup>C₆; OSI-774-<sup>13sup>C₆		Alkynes
Erlotinib- ¹³C₆ is a ¹³C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].

HY-12008S1

Erlotinib-13C6 hydrochloride CP-358774-<sup>13sup>C₆ hydrochloride; NSC 718781-<sup>13sup>C₆ hydrochloride; OSI-774-<sup>13sup>C₆ hydrochloride		Alkynes
Erlotinib- ¹³C₆ (hydrochloride) is the ¹³C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0216S2

Ethynyl Estradiol-13C2 17α-Ethynylestradiol-<sup>13sup>C₂; Ethynylestradiol-<sup>13sup>C₂		Alkynes
Ethynyl Estradiol- ¹³C₂ is the ¹³C-labeled Ethynyl Estradiol. Ethynyl Estradiol-13C2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-14605BS

Rasagiline-13C3 mesylate racemic AGN1135-<sup>13sup>C₃; TVP1012-<sup>13sup>C₃ racemic		Alkynes
Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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