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Results for "

beta2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (5) Adiponectin Receptor (2) Adrenergic Receptor (193) AMPK (5) Amyloid-β (2) Androgen Receptor (1) Antibiotic (5) Apoptosis (9) Arrestin (1) Aurora Kinase (1) Autophagy (8) Bacterial (5) Biochemical Assay Reagents (2) c-Kit (1) Calcium Channel (3) Caspase (1) CCR (2) CDK (1) Chloride Channel (2) Cholinesterase (ChE) (4) Complement System (1) Dopamine Receptor (1) Dopamine Transporter (2) Drug Metabolite (3) Endogenous Metabolite (12) ERK (5) FAP (1) GABA Receptor (25) GSK-3 (1) Influenza Virus (2) Integrin (1) Isotope-Labeled Compounds (28) mAChR (11) MAP3K (1) MDM-2/p53 (1) Mitophagy (2) nAChR (87) NF-κB (3) NO Synthase (3) Organoid (4) p38 MAPK (6) Parasite (2) Phosphodiesterase (PDE) (1) Phospholipase (1) PKC (2) Potassium Channel (2) Proteasome (4) RAR/RXR (3) Renin (3) RET (1) Reverse Transcriptase (2) ROS Kinase (1) Sodium Channel (2) Src (1) TGF-beta/Smad (9) TGF-β Receptor (1) TRP Channel (1) VEGFR (1)
By Research Areas:	Cancer (58) Cardiovascular Disease (73) Endocrinology (98) Infection (11) Inflammation/Immunology (104) Metabolic Disease (33) Neurological Disease (138)
Oligonucleotides:	Antisense Oligonucleotides (4)

368

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Salbutamol hemisulfate 4 Publications Verification Albuterol hemisulfate; AH-3365 hemisulfate	Adrenergic Receptor Autophagy	Inflammation/Immunology Endocrinology Cancer
Salbutamol Hemisulfate (Albuterol hemisulfate) is a short-acting beta2-adrenoceptor agonist.

KCL-286	RAR/RXR	Others
Anticancer agent 168 is an orally active retinoic acid receptor (RAR/RXR) beta2 agonist with ameliorating effects on spinal cord injury (SCI) .

AC-261066	RAR/RXR	Cancer
AC-261066 is a potent, orally available and isoform-selective retinoic acid beta2 (RARbeta2) receptor agonist, with a pEC₅₀ of 8.0 .

Penbutolol sulfate 1 Publications Verification (-)-Terbuclomine	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Penbutolol sulfate is able to bind to both beta-1 adrenergic receptors and beta-2 adrenergic receptors (the two subtypes), thus making it a non-selective β blocker.

Salbutamol 4 Publications Verification Albuterol; AH-3365	Adrenergic Receptor ERK	Inflammation/Immunology Cancer
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the *β2-AR/ERK/EMT* pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) ^[2].

Mabuterol	Adrenergic Receptor	Cardiovascular Disease
Mabuterol is a selective and orally active **beta-2 adrenergic receptor (ADRB2)** agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

AZD-3199	Others	Inflammation/Immunology
AZD-3199 is an ultra-long-acting beta2 agonist with potential activity against asthma and chronic obstructive pulmonary disease .

Salbutamol hemisulfate (Standard)	Adrenergic Receptor Autophagy	Inflammation/Immunology Endocrinology Cancer
Salbutamol (hemisulfate) (Standard) is the analytical standard of Salbutamol (hemisulfate). This product is intended for research and analytical applications. Salbutamol Hemisulfate (Albuterol hemisulfate) is a short-acting beta2-adrenoceptor agonist.

Salbutamol adipate Albuterol adipate; AH-3365 adipate	Adrenergic Receptor ERK	Inflammation/Immunology Cancer
Salbutamol (Albuterol) adipate is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol adipate promotes tumorigenesis of gastric cancer cells through the *β2-AR/ERK/EMT* pathway. Salbutamol adipate is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) ^[2].

Mabuterol hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Mabuterol hydrochloride is a selective and orally active **beta-2 adrenergic receptor (ADRB2)** agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

Sibenadet hydrochloride AR-C68397AA	Dopamine Receptor Adrenergic Receptor	Inflammation/Immunology
Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, *beta2-adrenoceptor* agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea.

Batefenterol Succinate GSK961081 Succinate; TD-5959 Succinate	Adrenergic Receptor mAChR	Neurological Disease
Batefenterol Succinate (GSK961081 Succinate) is a first-of-its-kind inhaled bifunctional bronchodilator with smooth muscle relaxant properties. The activities of Batefenterol Succinate include acting as a smooth muscle parasympathetic antagonist and a beta2-adrenoceptor agonist. Batefenterol Succinate is used to improve respiratory function, especially in patients with chronic obstructive pulmonary disease (COPD) .

Salbutamol (Standard) Albuterol (Standard); AH-3365 (Standard)	Adrenergic Receptor ERK	Inflammation/Immunology Cancer
Salbutamol (Standard) is the analytical standard of Salbutamol. This product is intended for research and analytical applications. Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the *β2-AR/ERK/EMT* pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) ^[2].

Reproterol hydrochloride	Others	Others
Reproterol hydrochloride is a dual-acting beta2-adrenoceptor agonist and phosphodiesterase inhibitor. Reproterol hydrochloride is more potent than albuterol and feterol in stimulating cAMP production in human monocytes, demonstrating its potential in enhancing airway function. Furthermore, Reproterol significantly inhibited the production of LTB4, indicating its anti-inflammatory properties. Reproterol hydrochloride may have inhibitory effects in respiratory diseases such as asthma and COPD .

Mabuterol hydrochloride (Standard)	Adrenergic Receptor	Cardiovascular Disease
Mabuterol (hydrochloride) (Standard) is the analytical standard of Mabuterol (hydrochloride). This product is intended for research and analytical applications. Mabuterol hydrochloride is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

Reproterol (hydrochloride) (Standard)	Others	Others
Reproterol (hydrochloride) (Standard) is the analytical standard of Reproterol (hydrochloride). This product is intended for research and analytical applications. Reproterol hydrochloride is a dual-acting beta2-adrenoceptor agonist and phosphodiesterase inhibitor. Reproterol hydrochloride is more potent than albuterol and feterol in stimulating cAMP production in human monocytes, demonstrating its potential in enhancing airway function. Furthermore, Reproterol significantly inhibited the production of LTB4, indicating its anti-inflammatory properties. Reproterol hydrochloride may have inhibitory effects in respiratory diseases such as asthma and COPD .

Higenamine 3 Publications Verification Norcoclaurine; Demethyl-Coclaurine	MAP3K MDM-2/p53 Adrenergic Receptor ROS Kinase Apoptosis	Cardiovascular Disease Endocrinology
Higenamine (Norcoclaurine), a *β2-AR* agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor (IC₅₀=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor (β2-AR). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases ^[2] .

β2AR agonist 3	Adrenergic Receptor	Metabolic Disease
β2AR agonist 3 (compound 9a) is a β2-adrenergic receptor (β2AR) agonist. β2AR agonist 3 can be used for type 2 diabetes research .

β2AR antagonist 1	Adrenergic Receptor	Others
β2AR antagonist 1 (Cmpd-15PA) is an antagonist of β2 adrenergic receptor (β2AR). β2AR antagonist 1 binds to the intracellular surface of the β2AR .

β2AR/M-receptor agonist-1	mAChR Adrenergic Receptor	Cardiovascular Disease
β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC₅₀ value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a K_i value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC₅₀ value of 4.0 nM .

Proteasome β2c/i-IN-1	Proteasome	Others
Proteasome β2c/i-IN-1 (compound 37) is a subunit-selective human proteasome β2c and β2i inhibitor .

β2AR agonist 4	Adrenergic Receptor	Metabolic Disease
β2AR agonist 4 (compound A19) is a potent and selective β2-Adrenoceptor agonist with an EC₅₀ of 3.7 pM. β2AR agonist 4 suppresses the inflammatory cytokines and leukocytes upregulation and improves lung function in COPD rat model .

β2AR ligand 1	Adrenergic Receptor	Others
β2AR ligand 1 (Compound 4) is a homobivalent bitopic ligand for β2 adrenergic receptor (β2AR) on the orthosteric binding site (OBS) and the metastable binding sites (MBS) .

PF-4348235 β2AR/M-receptor agonist-2	mAChR Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology
β2AR/M-receptor agonist-2 (compound 15) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-2 shows potency to β2 adrenoceptor with an EC₅₀ value of 3.7 nM. β2AR/M-receptor agonist-2 also has potency to human cloned M3 receptor with a K_i value of 0.73 nM. β2AR/M-receptor agonist-2 is a potent bronchodilator, it can be used for the research of chronic obstructive pulmonary disease (COPD) .

β2AR/M3-receptor agonist-1	Adrenergic Receptor mAChR	Metabolic Disease
β2AR/M3-receptor agonist-1 (example 9) is a potent *β2AR* and M3 receptor agonist. β2AR/M3-receptor agonist-1 shows M3 receptor affinity with a pIC₅₀ value of 9.3. β2AR/M3-receptor agonist-1 has the potential for the research of respiratory tract disorders .

β2AR agonist 2	Adrenergic Receptor	Metabolic Disease
β2AR agonist 2(compound 8a) is a β₂ -Adrenergic receptor (β₂AR) agonist. β2AR agonist 2 is a saturated nitrogen ring compound containing 4- to 7-membered heterocycle. β2AR agonist 2 has a chiral structure (the -R form) by carrying carbon containing the essential hydroxyl, thereby enhancing cellular glucose uptake (GU) activity and significantly stimulating glucose uptake by skeletal muscle cells. β2AR agonist 2 can be used in the study of Type 2 Diabetes (T2D) .

2α-Hydroxy-8β-(2-methylbutyryloxy)costunolide	Others	Others
2α-Hydroxy-8β-(2-methylbutyryloxy)costunolide is a Sesquiterpenoids product that can be isolated from the aerial parts of Artemisia myriantha .

β2AR agonist /M-receptor antagonist-1	mAChR Adrenergic Receptor	Neurological Disease
β2AR agonist /M-receptor antagonist-1 is a potent dual *muscarinic antagonist/beta 2* agonist (MABA)**. β2AR agonist /M-receptor antagonist-1 potently relaxes either Carbachol (HY-B1208)-induced contraction, in the absence (MABA) or presence of Propranolol (M3; HY-B1208), or Histamine (HY-B1204)-induced contraction (β2) ^[2].

Formoterol hemifumarate hydrate 1 Publications Verification	Adrenergic Receptor	Neurological Disease Inflammation/Immunology
Formoterol hemifumarate hydrate is a selective, long-acting *beta 2-adrenoceptor* agonist. Formoterol is a bronchodilator used for the research of the asthma and chronic obstructive pulmonary disease (COPD). Formoterol hemifumarate hydrate induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury ^[2] .

8beta-(2-Hydroxy-2-methyl-3-oxobutyryloxy)glucozaluzanin C	Others	Others
8beta-(2-Hydroxy-2-methyl-3-oxobutyryloxy)glucozaluzanin C is a Sesquiterpenoids product that can be isolated from the herbs of Crepis crocea. .

Formoterol (hemifumarate hydrate) (Standard)	Adrenergic Receptor	Neurological Disease Inflammation/Immunology
Formoterol (hemifumarate hydrate) (Standard) is the analytical standard of Formoterol (hemifumarate hydrate). This product is intended for research and analytical applications. Formoterol hemifumarate hydrate is a selective, long-acting beta 2-adrenoceptor agonist. Formoterol is a bronchodilator used for the research of the asthma and chronic obstructive pulmonary disease (COPD). Formoterol hemifumarate hydrate induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury ^[2] .

*His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA*	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

Thermopsidine CC4	nAChR	Neurological Disease
Thermopsidine (CC4) is a selective partial agonist at α4β2/α6β2 nAChR with EC₅₀ values of 2.2 μM target α4β2 .

Olodaterol 1 Publications Verification BI1744	Adrenergic Receptor	Inflammation/Immunology Endocrinology
Olodaterol (BI1744) is a selective, long acting *β₂-adrenoceptor* (β₂-AR) agonist (EC₅₀=0.1 nM and pK_i= 9.14 for human β₂-adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis ^[2] .

Olodaterol hydrochloride 1 Publications Verification BI1744 hydrochloride	Adrenergic Receptor	Inflammation/Immunology Endocrinology
Olodaterol (BI1744) hydrochloride is a selective, long acting *β₂-adrenoceptor* (β₂-AR) agonist (EC₅₀=0.1 nM and pK_i= 9.14 for human β₂-adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis ^[2] .

Vilanterol trifenatate 5 Publications Verification GW642444 trifenatate	Adrenergic Receptor	Inflammation/Immunology Endocrinology Cancer
Vilanterol trifenatate (GW642444 trifenatate) is a long-acting *β₂-adrenoceptor* (β₂-AR) agonist with inherent 24-hour activity. The pEC₅₀s for β₂-AR, β₁-AR and β₃-AR are 10.37, 6.98 and 7.36, respectively.

Vilanterol 5 Publications Verification GW642444	Adrenergic Receptor	Inflammation/Immunology Endocrinology Cancer
Vilanterol (GW642444) is a long-acting *β₂-adrenoceptor* (β₂-AR) agonist with 24 h activity. The pEC₅₀s for β₂-AR,β₁-AR and β₃-AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively.

Clenproperol	Adrenergic Receptor	Endocrinology
Clenproperol is a *β2-adrenergic* agonist .

Mapenterol hydrochloride	Adrenergic Receptor	Endocrinology
Mapenterol hydrochloride is a type of *β2-adrenoceptor* agonist .

Olodaterol hydrochloride (Standard)	Adrenergic Receptor	Inflammation/Immunology Endocrinology
Olodaterol (hydrochloride) (Standard) is the analytical standard of Olodaterol (hydrochloride). This product is intended for research and analytical applications. Olodaterol (BI1744) hydrochloride is a selective, long acting *β₂-adrenoceptor* (β₂-AR) agonist (EC₅₀=0.1 nM and pK_i= 9.14 for human β₂-adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis ^[2] .

Br-PBTC	nAChR	Neurological Disease
Br-PBTC is a potent, 2/4 subtype-selective positive allosteric modulator of nAChRs (nicotinic acetylcholine receptors) with α2β2，α2β4，α4β2，α4β4，(α4β2)₂α4 and (α4β2)₂β2 EC₅₀ ranges from 0.1~0.6 μM. Br-PBTC acts from the c-tail of an α subunit .

Arformoterol maleate (R,R)-Formoterol maleate	Adrenergic Receptor	Inflammation/Immunology
Arformoterol ((R,R)-Formoterol) maleate, the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a K_d of 2.9 nM. Arformoterol maleate can be used for the research of chronic obstructive pulmonary disease (COPD) ^[2].

Arformoterol 1 Publications Verification (R,R)-Formoterol	Adrenergic Receptor	Inflammation/Immunology
Arformoterol ((R,R)-Formoterol), the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a K_d of 2.9 nM. Arformoterol can be used for the research of chronic obstructive pulmonary disease (COPD) ^[2].

LU-002i	Proteasome	Others
LU-002i is a subunit-selective human proteasome β2c and β2i inhibitor with an IC₅₀ value of 220 nM for β2i .

Arformoterol tartrate (R,R)-Formoterol tartrate	Adrenergic Receptor	Inflammation/Immunology
Arformoterol ((R,R)-Formoterol) tartrate, the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a K_d of 2.9 nM. Arformoterol tartrate can be used for the research of chronic obstructive pulmonary disease (COPD) ^[2].

Cat. No.	Product Name	Type

HY-P2975

Laminin β2

Human laminin

Native Proteins

Laminin β2 (Human laminin) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.

HY-40421

(R)-3-Fluoropyrrolidine hydrochloride	Biochemical Assay Reagents
(R)-3-Fluoropyrrolidine hydrochloride is a derivative of fluorinated pyrrolidines. The amide series of fluorinated pyrrolidines are inhibitors of dipeptidyl peptidase DP-IV. Novel α4β2 receptor ligands characterized by a 3-Fluoropyrrolidine core .

HY-W006443

2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate, 98%(N) 2,3,4,6-Tetra-O-acetyl-&beta	Carbohydrates
2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate, 98%(N) (2,3,4,6-Tetra-O-acetyl-&beta) can be used in glycobiology research.

Cat. No.	Product Name	Target	Research Area

HY-P4285

β-Aspartylalanine	Peptides	Others
β-Aspartylalanine is a substrate for β-aspartyl peptidase and used to measure β-aspartyl peptidase activity in fecal supernatants .

HY-P5189A

*His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA*	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

HY-P10255

K90-114TAT	Potassium Channel	Cancer
K90-114TAT is an inhibitor for EAG2-Kvβ2 interaction, and exhibits antitumor efficacy against glioblastomas .

HY-P5833

κ-Bungarotoxin κ-Bgt	nAChR	Neurological Disease
κ-Bungarotoxin (κ-Bgt) is a potent, selective, and slowly reversible antagonist of α3β2 neuronal nicotinic acetylcholine receptors with an IC₅₀ of 2.30 nM .

Cat. No.	Product Name	Target	Research Area

HY-P99020

Fresolimumab 1 Publications Verification GC1008	TGF-beta/Smad	Metabolic Disease Inflammation/Immunology Cancer
Fresolimumab (GC1008) is a human monoclonal antibody against *TGF-β* that neutralizes all mammalian active subtypes of *TGF-β. The binding affinity of Fresolimumab to TGF-β2* is 1.8 nM. Fresolimumab radiolabeled with ⁸⁹Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease ^[2] .

HY-P990140

*Anti-Rat β-2-Microglobulin Antibody (4C9)*	Inhibitory Antibodies	Others
Anti-Rat β-2-Microglobulin Antibody (4C9) is a mouse-derived IgG1 type antibody inhibitor, targeting to rat β-2-Microglobulin.

HY-P99695

Lerdelimumab CAT-152	TGF-beta/Smad	Neurological Disease
Lerdelimumab (CAT-152) is an IgG4 human *anti-TGF-β2* recombinant monoclonal antibody. Lerdelimumab can be used as an anti-scarring agent for glaucoma research ^[2].

Species:	Human (34) Rhesus Macaque (5) Mouse (14) Rat (7) Cynomolgus (10) Canine (1)
Tag:	SUMO (1) His (53) Tag Free (8) Avi (7) GST (2) Fc (7) Flag (2)
Source:	HEK293 (54) E. coli Cell-free (1) CHO (1) Sf9 insect cells (2) E. coli (12)

Cat. No.	Compare	Product Name	Species	Source

HY-P73304

	*NRG1-beta 2* Protein, Human** NRG-1 EGF-like domain beta 2; beta2; Neuregulin-1 beta 2	Human	E. coli
	HRG1-β1 belongs to a family of structurally-related polypeptide growth factors derived from alternatively spliced genes, induces Fn14 expression in MCF7 cells. NRG1-beta 2 Protein, Human is the recombinant human-derived NRG1-beta 2 protein, expressed by E. coli , with tag free. The total length of NRG1-beta 2 Protein, Human is 61 a.a., with molecular weight of ~7.0 kDa.

HY-P702206

	ADRB2 Protein, Human (Cell-Free, His, SUMO) beta-2 adrenergic receptor; beta-2 adrenoreceptor; beta-2 adrenoceptor	Human	E. coli Cell-free
	ADRB2 protein is an important member of the β-adrenergic receptor family and mediates catecholamine-induced adenylyl cyclase activation through G protein action. It has 30 times greater affinity for epinephrine and plays a crucial role in cellular responses to sympathetic nervous system stimulation. ADRB2 Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived ADRB2 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag and G16R, E27Q mutation. The total length of ADRB2 Protein, Human (Cell-Free, His, SUMO) is 413 a.a., with molecular weight of 65 kDa.

HY-P71131

	*Tryptase beta-2* Protein, Mouse (HEK293, His)** 1 Publications Verification Tryptase beta-2; Tryptase-2; Mast cell protease 6; mMCP-6	Mouse	HEK293
	Tryptase beta-2, a neutral protease abundant in mast cells, plays a key role in innate immunity.As the primary proteolytic enzyme released during mast cell activation, Tryptase beta-2 contributes significantly to immune functions.Its involvement underscores its importance in mediating cellular responses linked to innate immunity, highlighting its role in the intricate defense mechanisms of the immune system.Tryptase beta-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tryptase beta-2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73863

	*Integrin alpha X beta 2* Protein, Human (HEK293, His)** Integrin alpha X beta 2; CD11c; ITGAX; CD18; ITGB2	Human	HEK293
	Integrin α-X/β-2 is a receptor for fibrinogen that recognizes GPR sequences. It plays a key role in inflammatory responses, particularly in monocyte adhesion and chemotaxis. Integrin alpha X beta 2 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha X beta 2 Protein, Human (HEK293, His), has molecular weight of 130-150 kDa (ITGAX) & 85-96 kDa (ITGB2), respectively.

HY-P74834

	*IL-12R beta 2* Protein, Mouse (HEK293, His)** Interleukin-12 receptor subunit beta-2; IL-12R-beta-2; IL-12RB2	Mouse	HEK293
	IL-12R beta 2 protein is an IL-12 cytokine surface receptor that activates the Jak-Stat signaling cascade pathway and is involved in IL-12-mediated immune regulation. IL-12R beta 2 Protein, Mouse (HEK293, His) is expressed by HEK 293 cells with a transmembrane region (W638-I658) and a His tag at the C-terminus.

HY-P73864

	*Integrin alpha X beta 2* Protein, Human (HEK293, Flag, His)** Integrin alpha X beta 2; CD11c; ITGAX; CD18; ITGB2	Human	HEK293
	Integrin α-X/β-2 is a receptor for fibrinogen that recognizes GPR sequences. It plays a key role in inflammatory responses, particularly in monocyte adhesion and chemotaxis. Integrin alpha X beta 2 Protein, Human (HEK293, Flag, His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein, expressed by HEK293 , with C-His, C-Flag labeled tag.

HY-P71315

	*SIRP beta 2* Protein, Human (HEK293, Fc)** dJ776F14.2; PTPN1L; PTPNS1L3; Signal-Regulatory Protein beta 2; Signal-Regulatory Protein beta-2; SIRP beta 2; SIRP-beta-2; SIRPG	Human	HEK293
	SIRP beta 2 Protein, a novel positive regulator of innate immunotherapy, is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP beta 2 is expressed on myeloid cells at protein level and enhanced adhesion, differentiation, cancer cell phagocytosis and T cell activation in an in vitro setting. DAP12 is responsible for SIRP beta 2 signaling, and is recruited through a single, positive lysine residue in the transmembrane domain of SIRP beta 2. SIRP beta 2 Protein, Human (HEK293, Fc) is the recombinant human-derived SIRP beta 2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72596

	*IL-12R beta 2* Protein, Mouse (HEK293, Fc)** Interleukin-12 receptor subunit beta-2; IL-12R-beta-2; IL-12RB2	Mouse	HEK293
	IL-12R beta 2 protein is an IL-12 cytokine surface receptor that activates the Jak-Stat signaling cascade pathway and is involved in IL-12-mediated immune regulation. IL-12R beta 2 Protein, Mouse (HEK293, Fc) is expressed by HEK293 cells with a hFc tag at the C-terminus.

HY-P700857

	*GARP&Latent TGF Beta 2* Complex Protein, Human (HEK293, His-Avi)** Garpin; GARP; LRRC32; D11S833E; GARP&Latent TGF B; GARP&TGF B; Cetermin; G-TSF; LAP; TGF-beta-2; TGF beta 2; GARP&Latent TGF beta 2	Human	HEK293
	LRRC32, a key regulator of TGF-beta activation, maintains TGFB1, TGFB2, and TGFB3 in a latent state during extracellular storage by binding to Latency-associated peptide (LAP). Competing with LTBP1 for LAP binding, LRRC32 effectively modulates integrin-dependent TGF-beta activation. Its significance spans the regulation of TGF-beta-1 (TGFB1) on activated Tregs' surface and the control of TGF-beta-3 (TGFB3) during palate development, emphasizing LRRC32's intricate role in fine-tuning TGF-beta signaling. Interactions with TGFB1, TGFB2, TGFB3, and LAPTM4B contribute to its regulatory functions. GARP&Latent TGF Beta 2 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP&Latent TGF Beta 2 Complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 2 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 72-77 kDa(GARP) & 13 kDa & 46-48 kDa(Latent TGF Beta 2), respectively.

HY-P71447

	GABRB2 Protein, Human (His) GABA(A) receptor subunit beta-2	Human	E. coli
	GABRB2 protein is an important component of heteropentameric GABA receptors that form ligand-gated chloride channels. It plays a crucial role in establishing functional inhibitory GABAergic synapses, contributing to synaptic depression. GABRB2 Protein, Human (His) is the recombinant human-derived GABRB2 protein, expressed by E. coli , with N-His labeled tag.

HY-P76051

	SCN2B Protein, Human (HEK293, Fc) Sodium channel subunit beta-2; SCN2B	Human	HEK293
	SCN2B protein is a key subunit of voltage-gated sodium channels and plays an important role in regulating channel function by interacting with the pore-forming α subunit. This interaction regulates the flux of sodium ions across the cell membrane, affecting neuronal excitability and action potential propagation. SCN2B Protein, Human (HEK293, Fc) is the recombinant human-derived SCN2B protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76052

	SCN2B Protein, Human (HEK293, His) Sodium channel subunit beta-2; SCN2B	Human	HEK293
	SCN2B protein is a key subunit of voltage-gated sodium channels and plays an important role in regulating channel function by interacting with the pore-forming α subunit. This interaction regulates the flux of sodium ions across the cell membrane, affecting neuronal excitability and action potential propagation. SCN2B Protein, Human (HEK293, His) is the recombinant human-derived SCN2B protein, expressed by HEK293 , with C-His labeled tag.

HY-P700758

	*Integrin alpha L beta 2* Protein, Mouse (HEK293, His)** αLβ2; ITGAL&ITGB2; ITGAL; ITGB2	Mouse	HEK293
	Integrin alpha L beta 2 Protein, a receptor for ICAM1, ICAM2, ICAM3, ICAM4, and F11R, participates in immune phenomena, including leukocyte-endothelial cell interaction, cytotoxic T-cell killing, and antibody-dependent killing. It contributes to natural killer cell cytotoxicity and leukocyte adhesion and transmigration. Essential for common lymphoid progenitor cell generation, indicating a role in lymphopoiesis. In association with ICAM3, it contributes to apoptotic neutrophil phagocytosis by macrophages. Interacts with THBD. Integrin alpha L beta 2 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha L beta 2 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha L beta 2 Protein, Mouse (HEK293, His), has molecular weight of 160-180 kDa (ITGAL) & 90-105 kDa (ITGB2), respectively.

HY-P70844

	HSPB2 Protein, Human (His) Heat shock protein beta-2; HspB2; DMPK-binding protein; MKBP;	Human	E. coli
	HSPB2 Protein potentially regulates the kinase DMPK, enhancing its activity and influencing cellular processes. The specific mechanisms and broader implications in cellular signaling pathways require elucidation. Comprehensive studies are essential to unravel the precise molecular pathways and functional significance of the HSPB2-DMPK interplay, shedding light on its potential contributions to cellular regulation and signaling cascades. HSPB2 Protein, Human (His) is the recombinant human-derived HSPB2 protein, expressed by E. coli , with C-6*His labeled tag. The total length of HSPB2 Protein, Human (His) is 182 a.a., with molecular weight of ~22.0 kDa.

HY-P71125

	TPSB2 Protein, Human (HEK293, His) Tryptase beta-2; Tryptase-2; Tryptase II; TPSB2; TPS2	Human	HEK293
	TPSB2 Protein, Human (HEK293, His) is the recombinant human-derived TPSB2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TPSB2 Protein, Human (HEK293, His) is 257 a.a., with molecular weight of 30-35 kDa.

HY-P75587

	ATP1B2 Protein, Human (HEK293, His) Sodium/potassium-transporting ATPase subunit beta-2; AMOG; ATP1B2	Human	HEK293
	The ATP1B2 protein is the non-catalytic component of ATP hydrolase and promotes Na(+)/K(+) ion exchange across the plasma membrane. Its role is critical in mediating cell adhesion of neurons and astrocytes, promoting sticky cell interactions. ATP1B2 Protein, Human (HEK293, His) is the recombinant human-derived ATP1B2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ATP1B2 Protein, Human (HEK293, His) is 223 a.a., with molecular weight of 40-60 kDa.

HY-P700759

	*Integrin alpha M beta 2* Protein, Human (HEK293, His)** αMβ2; ITGAM&ITGB2; ITGAM; ITGB2; Mac-1; complement receptor-3 (CR3)	Human	HEK293
	Integrin α M β 2 (ITGAM/ITGB2) mediates adhesion of monocytes and granulocytes and promotes uptake of complement-coated particles and pathogens. As a receptor for iC3b and fibrinogen, it regulates neutrophil migration, contributes to CD177-PRTN3-mediated activation, and may influence phagocytosis-induced apoptosis. Integrin alpha M beta 2 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha M beta 2 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha M beta 2 Protein, Human (HEK293, His), has molecular weight of 140-160 kDa (ITGAM) & 90-100 kDa (ITGB2), respectively.

HY-P78521

	SIRP gamma Protein, Human (HEK293, His-Avi) CD172g; FLJ42230; SIRP beta 2; SIRP gamma; SIRP-B2; SIRPG; Cripto-1; bA77C3.1; SIRP β 2	Human	HEK293
	SIRP γ protein is a possible immunoglobulin-like cell surface receptor that mediates cell-cell adhesion by binding to CD47. This interaction enhances antigen-specific T cell proliferation and provides costimulatory signals for T cell activation, highlighting the role of SIRP gamma in regulating immune responses. SIRP gamma Protein, Human (HEK293, His-Avi) is the recombinant human-derived SIRP gamma protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P78210

	SIRP gamma Protein, Human (Biotinylated, HEK293, His-Avi) CD172g; FLJ42230; SIRP beta 2; SIRP gamma; SIRP-B2; SIRPG; Cripto-1; bA77C3.1; SIRP β 2	Human	HEK293
	SIRP γ protein is a possible immunoglobulin-like cell surface receptor that mediates cell-cell adhesion by binding to CD47. This interaction enhances antigen-specific T cell proliferation and provides costimulatory signals for T cell activation, highlighting the role of SIRP gamma in regulating immune responses. SIRP gamma Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SIRP gamma protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P70649

	*TGF beta 2/TGFB2 Protein, Mouse/Rat (HEK293)* 1 Publications Verification TGFB2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; MGC116892; Polyergin; TGF-beta2; TGF-beta-2; transforming growth factor beta-2	Mouse;Rat	HEK293
	Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Mouse/Rat (HEK293) is produced in HEK293 cells.

HY-P7044G

	GMP IL-6 Protein, Human 1 Publications Verification Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon beta-2; IFN-beta-2; IL6; IFNB2	Human	E. coli
	IL-6 protein is a multifunctional cytokine that plays multiple biological functions in immunity, tissue regeneration, and metabolism. After binding to IL6R, the resulting complex binds to the signaling subunit IL6ST/gp130, triggering the intracellular IL6 signaling pathway. GMP IL-6 Protein, Human is the recombinant human-derived IL-6 protein, expressed by E. coli , with tag free. GMP IL-6 Protein, Human, has molecular weight of ~20.0 kDa.

HY-P77488

	SIRP gamma Protein, Cynomolgus (HEK293, Fc) Signal-Regulatory Protein Gamma; CD172 Antigen-Like Family Member B; Signal-Fegulatory Protein beta-2; SIRP-b2; SIRP-beta-2; CD172g; SIRPG; SIRPB2	Cynomolgus	HEK293
	SIRP gamma Protein, a member of signal-regulatory protein (SIRP) family, is the only SIRP detected on T cells and activated NK cells. SIRP gamma can bind CD47, providing T cells and NK cells with a cell surface molecule capable of interacting with CD47. SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact, enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion. SIRP gamma Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived SIRP gamma protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77489

	SIRP gamma Protein, Cynomolgus (HEK293, His) Signal-Regulatory Protein Gamma; CD172 Antigen-Like Family Member B; Signal-Fegulatory Protein beta-2; SIRP-b2; SIRP-beta-2; CD172g; SIRPG; SIRPB2	Cynomolgus	HEK293
	SIRP gamma Protein, a member of signal-regulatory protein (SIRP) family, is the only SIRP detected on T cells and activated NK cells. SIRP gamma can bind CD47, providing T cells and NK cells with a cell surface molecule capable of interacting with CD47. SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact, enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion. SIRP gamma Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived SIRP gamma protein, expressed by HEK293 , with C-His labeled tag.

HY-P71316

	SIRP gamma Protein, Human (HEK293, Fc) Signal-Regulatory Protein Gamma; SIRP-Gamma; CD172 Antigen-Like Family Member B; Signal-Fegulatory Protein beta-2; SIRP-b2; SIRP-beta-2; CD172g; SIRPG; SIRPB2	Human	HEK293
	SIRP γ protein is a possible immunoglobulin-like cell surface receptor that mediates cell-cell adhesion by binding to CD47. This interaction enhances antigen-specific T cell proliferation and provides costimulatory signals for T cell activation, highlighting the role of SIRP gamma in regulating immune responses. SIRP gamma Protein, Human (HEK293, Fc) is the recombinant human-derived SIRP gamma protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P7044AF

	Animal-Free IL-6 Protein, Human (His) Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon beta-2; IFN-beta-2; IL6; IFNB2	Human	E. coli
	IL-6 protein is a multifunctional cytokine that plays multiple biological functions in immunity, tissue regeneration, and metabolism. After binding to IL6R, the resulting complex binds to the signaling subunit IL6ST/gp130, triggering the intracellular IL6 signaling pathway. Animal-Free IL-6 Protein, Human (His) is the recombinant human-derived animal-FreeIL-6 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-6 Protein, Human (His) is 184 a.a., with molecular weight of ~21.8 kDa.

HY-P7119

	*TGF beta 2/TGFB2 Protein, Human* 5+ Cited Publications TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2	Human	HEK293
	Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Human is produced in HEK293 cells, and consists of 112 amino acids (A303-S414).

HY-P700785

	*TGF beta 2/TGFB2 Protein, Human (HEK293, Avi)* 1 Publications Verification TGFB2; TGFBR2; TGFR2; TbetaR-II; TGFβR2; BB105277; TGF-beta 2; TβR-II; TGF-β 2	Human	HEK293
	In the TGF-beta-2 pathway, the TGF beta 2/TGFB2 protein serves as a precursor to latency-associated peptide (LAP) and transforming growth factor beta-2 (TGF-beta-2), regulating their formation. Crucially, TGF-β2/TGFB2 maintains TGF-β-2 in a latent state within the extracellular matrix, forming a non-covalent association with TGF-β-2. TGF beta 2/TGFB2 Protein, Human (HEK293, Avi) is the recombinant human-derived TGF beta 2/TGFB2 protein, expressed by HEK293 , with C-Avi labeled tag. The total length of TGF beta 2/TGFB2 Protein, Human (HEK293, Avi) is 112 a.a., with molecular weight of 14.53 kDa.

HY-P73614

	*TGF beta 2/TGFB2 Protein, Canine (HEK293, His)* TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2	Canine	HEK293
	Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Canine (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It and consists of 414 amino acids (M1-S414).

HY-P78240

	*B2M/Beta-2* microglobulin Protein, Mouse (HEK293, Fc)** beta-2-microglobulin; B2M; β-2-microglobulin	Mouse	HEK293
	Beta-2 microglobulin (B2M) is vital in presenting antigens to the immune system through MHC class I molecules. It forms a heterodimer with an alpha chain to create MHC class I molecules. B2M also forms a heterotrimer with MR1 and a metabolite antigen, enhancing antigen presentation and immune recognition. B2M's molecular interactions facilitate immune system functioning and foreign substance recognition. B2M/Beta-2 microglobulin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Mouse (HEK293, Fc) is 99 a.a., with molecular weight of 40-50 kDa.

HY-P73613

	*TGF beta 2/TGFB2 Protein, Rhesus Macaque (HEK293, His)* TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2	Rhesus Macaque	HEK293
	Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It and consists of 414 amino acids (M1-S414).

HY-P73613A

	*TGF beta 2/TGFB2 Protein, Rhesus Macaque (HEK293, C-His)* TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2	Rhesus Macaque	HEK293
	Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It and consists of 414 amino acids (M1-S414).

HY-P74403

	*B2M/Beta-2* microglobulin Protein, Mouse (HEK293, His)** beta-2-microglobulin; B2M	Mouse	HEK293
	Beta-2 microglobulin (B2M) is vital in presenting antigens to the immune system through MHC class I molecules. It forms a heterodimer with an alpha chain to create MHC class I molecules. B2M also forms a heterotrimer with MR1 and a metabolite antigen, enhancing antigen presentation and immune recognition. B2M's molecular interactions facilitate immune system functioning and foreign substance recognition. B2M/Beta-2 microglobulin Protein, Mouse (HEK293, His) is the recombinant mouse-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Mouse (HEK293, His) is 99 a.a., with molecular weight of ~14.5 kDa.

HY-P75592

	*B2M/Beta-2* microglobulin Protein, Cynomolgus (HEK293, His)** beta-2-microglobulin; B2M	Cynomolgus	HEK293
	B2M protein is essential for MHC class I complex, presenting antigens and enabling immune recognition. B2M forms heterodimers with alpha chains, constituting MHC class I molecules. Its participation ensures immune system function and foreign substance recognition. B2M/Beta-2 microglobulin Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag.

HY-P74402

	*B2M/Beta-2* microglobulin Protein, Rat (HEK293, His, solution)** beta-2-microglobulin; B2M	Rat	HEK293
	Beta-2 microglobulin protein (B2M) is crucial in presenting antigens, aiding immune surveillance.B2M forms a complex with an alpha chain, creating MHC class I molecules for antigen recognition.It also participates in a heterotrimer with MR1, expanding its role in antigen presentation and immune signaling pathways.B2M's intricate interactions underscore its significance in orchestrating immune responses.B2M/Beta-2 microglobulin Protein, Rat (HEK293, His, solution) is the recombinant rat-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag.

HY-P74404

	*B2M/Beta-2* microglobulin Protein, Human (HEK293, His, solution)** beta-2-microglobulin; B2M	Human	HEK293
	B2M is a component of MHC class I complexes that present peptide antigens to the immune system. B2M/Beta-2 microglobulin Protein, Human (HEK293, His, solution) is the recombinant human-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Human (HEK293, His, solution) is 99 a.a., with molecular weight of ~13.5 kDa.

HY-P7625

	*B2M/Beta-2-microglobulin Protein, Human (His)* rHubeta-2-microglobulin, His; beta-2-Microglobulin; B2M	Human	E. coli
	B2M/Beta-2-microglobulin Protein is a secreted protein found on the outside of the cell membrane. B2M/Beta-2-microglobulin Protein is a crucial component of MHC class I molecules, essential for presenting tumor antigens to T cells. B2M/Beta-2-microglobulin Protein is a systemic pro-aging factor that can impair cognitive function and neurogenesis. B2M/Beta-2-microglobulin Protein, Human (His) is a recombinant human Beta-2-microglobulin protein with a His tag, expressed in E. coli.

HY-P78625

	*B2M/Beta-2* microglobulin Protein, Rat (99a.a, HEK293, His)** beta-2-microglobulin; B2M	Rat	HEK293
	B2M or Beta-2 microglobulin binds to MHC class II protein complexes and forms homodimers. It responds to cadmium ions and exogenous stimuli and is present in the extracellular space. B2M/Beta-2 microglobulin Protein, Rat (HEK293, His) is the recombinant rat-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag.

HY-P73744

	*NRG1-beta 2* Protein, Human (HEK293, His)** Pro-NRG1; Neuregulin-1; ARIA; HRG; NRG1	Human	HEK293
	NRG1-beta 2 Protein, Human (HEK293, His) is the recombinant human-derived NRG1-beta 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of NRG1-beta 2 Protein, Human (HEK293, His) is 219 a.a., with molecular weight of ~25.3 kDa.

HY-P73745

	*NRG1-beta 2* Protein, Human (HEK293, Fc)** Pro-NRG1; Neuregulin-1; ARIA; HRG; NRG1	Human	HEK293
	NRG1-beta 2 Protein, Human (HEK293, Fc) is the recombinant human-derived NRG1-beta 2 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of NRG1-beta 2 Protein, Human (HEK293, Fc) is 61 a.a., with molecular weight of ~35.5 kDa.

HY-P70046

	*B2M/Beta-2-microglobulin Protein, Human (HEK293, His)* rHubeta-2-microglobulin/B2M, His; beta-2-Microglobulin; B2M	Human	HEK293
	B2M is a component of MHC class I complexes that present peptide antigens to the immune system. B2M/Beta-2-microglobulin Protein, Human (HEK293, His) is the recombinant human-derived B2M/Beta-2-microglobulin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B2M/Beta-2-microglobulin Protein, Human (HEK293, His) is 99 a.a., with molecular weight of ~14.0 kDa.

HY-P700749

	IL-6 Protein, Cynomolgus (HEK293, His) IFN-beta-2; IL6; IL-6; BSF-2; CDF; MGI-2A; Interleukin-6; HSF; IFNB2; HGF; IFN-β-2	Cynomolgus	HEK293
	IL-6 is a cytokine with multiple functions in immunity, tissue regeneration, and metabolism, coordinating complex signaling. Binding to IL6R initiates the IL6 signaling pathway through a complex with the signaling subunit IL6ST/gp130. IL-6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-6 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-6 Protein, Cynomolgus (HEK293, His) is 185 a.a., with molecular weight of 25-30 kDa.

HY-P700660

	Apolipoprotein H/APOH Protein, Cynomolgus (HEK293, His) Apo-H; B2GP1; B2G1; APOH; B2GPI; beta(2)GPI; BG; β(2)GPI;	Cynomolgus	HEK293
	Apolipoprotein H/APOH proteins have multiple functions and can bind to negatively charged substances such as heparin and phospholipids. Its diverse interactions highlight the adaptability that is critical for preventing activation of the intrinsic coagulation cascade by binding to phospholipids on the surface of damaged cells. Apolipoprotein H/APOH Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Apolipoprotein H/APOH protein, expressed by HEK293 , with C-His labeled tag. The total length of Apolipoprotein H/APOH Protein, Cynomolgus (HEK293, His) is 326 a.a., with molecular weight of 50-65 kDa.

HY-P7063

	IL-6 Protein, Mouse 5+ Cited Publications rMuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Mouse	E. coli
	IL-6 Protein, Mouse is a multifunctional cytokine that can regulate various immune and inflammatory responses.

HY-P7044

	IL-6 Protein, Human Maximum Cited Publications 31 Publications Verification rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Human	E. coli
	IL-6 Protein, Human is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.

HY-P76143

	*AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST)* 5'-AMP-activated protein kinase; AMPK; AMPK (α1, β2, γ1) Protein	Human	Sf9 insect cells
	The AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), a crucial regulator of cellular energy metabolism. Activated by low ATP levels, it enhances energy production while suppressing biosynthetic processes and cell growth. The gamma subunit mediates AMP, ADP, and ATP binding, influencing AMPK activation or inhibition. Allosteric AMP binding activates the alpha subunit, while ADP stimulates phosphorylation, and ATP promotes dephosphorylation, rendering AMPK inactive. Additionally, AMPK modulates cellular polarity and interacts with FNIP1 and FNIP2. AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 2/alpha 1 Heterotrimer protein, expressed by Sf9 insect cells, with N-His, N-GST labeled tag. AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~35 & 37 & 95 KDa, respectively.

HY-P76144

	*AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST)* 5'-AMP-activated protein kinase; AMPK; AMPK (α2, β2, γ1) Protein	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 2/alpha 2 Heterotrimer protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~35 & 37 & 95 KDa, respectively.

HY-P7044A

	IL-6 Protein, Human (CHO) 1 Publications Verification rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Human	CHO
	IL-6 Protein, Human (CHO) is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.

HY-P700151AF

	*Animal-Free TGF beta 2/TGFB2 Protein, Human (His)* G-TSF; LDS4; TGFB2	Human	E. coli
	In the TGF-beta-2 pathway, the TGF beta 2/TGFB2 protein serves as a precursor to latency-associated peptide (LAP) and transforming growth factor beta-2 (TGF-beta-2), regulating their formation. Crucially, TGF-β2/TGFB2 maintains TGF-β-2 in a latent state within the extracellular matrix, forming a non-covalent association with TGF-β-2. Animal-Free TGF beta 2/TGFB2 Protein, Human (His) is the recombinant human-derived animal-FreeTGF beta 2/TGFB2 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free TGF beta 2/TGFB2 Protein, Human (His) is 112 a.a., with molecular weight of ~13.66 kDa.

HY-P7063A

	IL-6 Protein, Mouse (His) rMuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Mouse	E. coli
	IL-6 protein is involved in various functions such as immunity, tissue regeneration and metabolism.IL-6 Protein, Mouse (His) is the recombinant mouse-derived IL-6 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P7103A

	IL-6 Protein, Rat (HEK293) 3 Publications Verification rRtIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2	Rat	HEK293
	IL-6 Protein, Rat (HEK293) is a HEK293 cell derived multifunctional cytokine that can regulate various immune and inflammatory responses.

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HY-14300AS

Vilanterol-d4 trifenatate
Vilanterol-d₄ (trifenatate) is deuterium labeled Vilanterol (trifenatate). Vilanterol trifenatate (GW642444 trifenatate) is a long-acting β2-adrenoceptor (β2-AR) agonist with inherent 24-hour activity. The pEC50s for β2-AR, β1-AR and β3-AR are 10.37, 6.98 and 7.36, respectively.

HY-B0010AS

Formoterol-d3
Formoterol-d₃ is deuterium labeled Arformoterol. Arformoterol ((R,R)-Formoterol), the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a Kd of 2.9 nM. Arformoterol can be used for the research of chronic obstructive pulmonary disease (COPD)[1][2].

HY-100699S

Clenproperol-d7
Clenproperol-d₇ is the deuterium labeled Clenproperol. Clenproperol is a β2-adrenergic agonist[1].

HY-B0452S1

Ritodrine-d3 hydrochloride
Ritodrine-d₃ (hydrochloride) is the deuterium labeled Ritodrine (hydrochloride). Ritodrine hydrochloride (DU21220 hydrochloride) is a β-2 adrenergic receptor agonist.

HY-13338S

Mabuterol-d9
Mabuterol-d₉ is a deuterium labeled Mabuterol. Mabuterol is an agonist of the β2-adrenergic receptor[1].

HY-136435S1

Mapenterol-d6 hydrochloride
Mapenterol-d₆ (hydrochloride) is the deuterium labeled Mapenterol hydrochloride. Mapenterol hydrochloride is a type of β2-adrenoceptor agonist[1][2].

HY-15746S1

(rac)-Dobutamine-d6 hydrochloride

(rac)-Dobutamine-d₆ (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion[1][2][3][4].

HY-15746S

(rac)-Dobutamine-d4 hydrochloride

(rac)-Dobutamine-d₄ (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion[1][2][3][4].

HY-B1276S

Metaproterenol-d7 hemisulfate
Metaproterenol-d₇ (hemisulfate) is the deuterium labeled Metaproterenol hemisulfate. Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity[1][2].

HY-B0010S

Formoterol-d6
Formoterol-d₆ is the deuterium labeled Formoterol. Formoterol ((±)Formoterol) is a potent, selective and long-acting β2-adrenoceptor agonist[1].

HY-131106S

Clorprenaline-d7
Clorprenaline-d₇ is a deuterium labeled Clorprenaline. Clorprenaline is a β2-adrenergic receptor agonist that is implicated in bronchial expansion. Clorprenaline has the potential for asthma research[1].

HY-B1037S

Salbutamol-d3
Salbutamol-d₃ is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).

HY-B1037S2

Salbutamol-d9
Salbutamol-d₉ is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).

HY-B1037S3

Salbutamol-d9 acetate
Salbutamol-d₉ (acetate) is the deuterium labeled Salbutamol[1]. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).

HY-10019S1

Varenicline-15N,13C,d2

Varenicline- ¹⁵N, ¹³C,d₂ is ¹⁵N and deuterated labeled Varenicline (HY-10019). Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC₅₀=250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation ^[2] .

HY-10020S

Varenicline-15N3 hydrochloride

Varenicline-15N3 Hydrochloride (CP 526555-15N3 Hydrochloride) is the ¹⁵N labeled isotope of Varenicline hydrochloride (HY-10020). Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC₅₀ = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation ^[2] .

HY-157502S

Buctopamine-d9
Buctopamine-d9 is the deuterium labeled Buctopamine. Buctopamine is a β2 adrenoceptor agonist .

HY-129029S

Bisoprolol-d5
Bisoprolol-d₅ is the deuterium labeled Bisoprolol. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2].

HY-B1810S

Tulobuterol-D9 hydrochloride
Tulobuterol-d₉ (hydrochloride) is the deuterium labeled Tulobuterol. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength[1].

HY-135119

Salmeterol-d3
Salmeterol-d₃ is a deuterium labeled Salmeterol. Salmeterol is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1].

HY-14302S1

Salmeterol-d5
Salmeterol-d5 is a deuterated labeled Salmeterol . Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC₅₀s of 9.6, 6.1, and 5.9, respectively ^[2].

HY-B0976AS

Fenoterol-d6 hydrobromide
Fenoterol-d₆ (hydrobromide) (Th-1165a-d6) is the deuterium labeled Fenoterol hydrobromide. Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research[1][2].

HY-17453S

Salmeterol-d3 xinafoate
Salmeterol-d₃ (xinafoate) is the deuterium labeled Salmeterol xinafoate. Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1].

HY-17453S1

Salmeterol-13C6 xinafoate
Salmeterol- ¹³C₆ (xinafoate) is the ¹³C₆ labeled Salmeterol (xinafoate). Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.

HY-100634S

4-Hydroxypropranolol-d7 hydrochloride

4-Hydroxypropranolol-d₇ (hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency comparable to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

HY-B0942S

Benzethonium-d7 chloride
Benzethonium-d7 chloride is the deuterium labeled Benzethonium chloride. Benzethonium chloride inhibit human recombinant α7 and α4β2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes.

HY-100634SA

4-Hydroxypropranolol-d7

4-Hydroxypropranolol-d₇ is the deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

HY-W015061S

N-(Phenylacetyl-d5)glycine
N-(Phenylacetyl-d₅)glycine is the deuterium labeled Phenylacetylglycine. Phenylacetylglycine is a gut microbial metabolite that can activate β2AR. Phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion[1][2].

HY-Y0313S1

p-Hydroxybenzaldehyde-13C
p-Hydroxybenzaldehyde- ¹³C is the ¹³C-labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

HY-Y0313S2

p-Hydroxybenzaldehyde-d5
p-Hydroxybenzaldehyde-d₅ is the deuterium labeled p-Hydroxybenzaldehyde[1]. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations[2].

HY-12766S

Bupropion morpholinol-d6
Bupropion morpholinol-d6 is the deuterated form of Bupropion morpholinol. Bupropion morpholinol is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities .

HY-16579AS2

Etifoxine-d5
Etifoxine-d₅ is the deuterium labeled Etifoxine. Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents[1][2][3].

HY-100935S

Cimaterol-d7
Cimaterol-d₇ is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.

HY-10019S

Varenicline-d4

Varenicline-d₄ is deuterium labeled Varenicline. Varenicline (CP 526555) is a potent partial agonist for α4β2 nicotinic acetylcholine receptor (nAChR) with an EC50 value of 2.3 μM. Varenicline is a full agonist for α3β4 and α7 nAChRs with EC50 values of 55 μM and 18 μM, respectively[1]. Varenicline is a nicotinic ligand based on the structure of cytisine, has the potential for smoking cessation treatment[2].

HY-A0009S

Galanthamine-d3 hydrobromide

Galanthamine-d₃ (hydrobromide) is deuterium labeled Galanthamine (hydrobromide). Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC50 of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α3β4, α4β2, α6β4 nicotinic receptors ( nAChRs). Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD)[1][2][3].

HY-10019AS1

Varenicline-d4 hydrochloride

Varenicline-d₄ hydrochloride is a deuterium labeled Varenicline (dihydrochloride) (HY-10019A) . Varenicline (CP 526555) dihydrochloride is a potent partial agonist for α4β2 nicotinic acetylcholine receptor (nAChR) with an EC₅₀ value of 2.3 μM. Varenicline dihydrochloride is a full agonist for α3β4 and α7 nAChRs with EC₅₀ values of 55 μM and 18 μM, respectively ^[2]. Varenicline dihydrochloride is a nicotinic ligand based on the structure of cytosine, and has the potential for smoking cessation treatment .

HY-B0573BS

Propranolol-d7

Propranolol-d₇ is the deuterium labeled Propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].

HY-B0573S

Propranolol-d7 hydrochloride

Propranolol-d₇ (hydrochloride) is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol hydrochloride is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].

HY-B0573S1

Propranolol-d7 (ring-d7)

Propranolol-d₇ (ring-d₇) is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].

HY-13342AS

Apatinib-d8 free base

Apatinib-d₈ (free base) is the deuterium labeled Apatinib free base[1]. Apatinib free base (YN968D1 free base) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 (IC50=1 nM). Apatinib free base (YN968D1 free base) is an anti-angiogenic drug for the research of advanced or metastatic gastric cancer. Apatinib free base (YN968D1 free base) potently inhibits Ret, c-Kit and c-Src with IC50s of 13, 429 and 530 nM, respectively. It also inhibits cellular phosphorylation of VEGFR-2, c-kit and PDGFRβ[2][3][4].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80432

	*PKC beta 2* Antibody**	WB, ICC/IF, IHC-P, IP, FC	Human, Mouse
	PKC beta 2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 77 kDa, targeting to PKC beta 2. It can be used for WB,ICC/IF,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.

HY-P81085

	ADRB2 Antibody beta 2-adrenergic receptor; beta 2 Adrenergic Receptor; ADRB2R; ADRBR; ADRB2_HUMAN; Adrenergic beta 2 receptor surface; B2AR; BAR; beta 2 adrenoreceptor; beta2AR; Catecholamine receptor; beta2-adrenergic receptor. β2-adrenergic receptor	WB, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat
	ADRB2 Antibody is an unconjugated, approximately 46 kDa, rabbit-derived, anti-ADRB2 polyclonal antibody. ADRB2 Antibody can be used for: WB, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, rabbit background without labeling.

HY-P80723

	IL-6 Antibody IL6; IFNB2; Interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2	WB, IHC-P, ELISA	Human
	IL-6 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 24 kDa, targeting to IL-6. It can be used for WB,IHC-P,ELISA assays with tag free, in the background of Human.

HY-P80795

	Phospho-CD18 (Ser745) Antibody ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150; 95 subunit beta; Complement receptor C3 subunit beta; CD antigen CD18	WB, IP	Human, Mouse, Rat
	Phospho-CD18 (Ser745) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 85 kDa, targeting to Phospho-CD18 (Ser745). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P82145

	Phospho-S6K2 (Ser371) Antibody (YA1890) RPS6KB2; STK14B; Ribosomal protein S6 kinase beta-2; S6K-beta-2; S6K2; 70 kDa ribosomal protein S6 kinase 2; P70S6K2; p70-S6K 2; S6 kinase-related kinase; SRK; Serine/threonine-protein kinase 14B; p70 ribosomal S6 kinase beta; S6K-beta; p70	WB	Human, Mouse, Rat
	Phospho-S6K2 (Ser371) Antibody (YA1890) is a biotin-conjugated non-conjugated IgG antibody, targeting Phospho-S6K2 (Ser371), with a predicted molecular weight of 53 kDa (observed band size: 60 kDa). Phospho-S6K2 (Ser371) Antibody (YA1890) can be used for WB experiment in human, mouse, rat background.

HY-P81260

	beta 2 Microglobulin Antibody (YA934) B2MG; beta 2 microglobin; beta 2 microglobulin; beta-2-microglobulin form pI 5.3; CDABP0092; Hdcma22p	ELISA	Human
	beta 2 Microglobulin Antibody (YA934) is a mouse-derived non-conjugated IgG2b antibody (Clone NO.: YA934), targeting beta 2 Microglobulin. beta 2 Microglobulin Antibody (YA934) can be used for ELISA experiment in human background.

HY-P81260A

	beta 2 Microglobulin Antibody (YA935) B2MG; beta 2 microglobin; beta 2 microglobulin; beta-2-microglobulin form pI 5.3; CDABP0092; Hdcma22p	WB, IP	Human, Mouse, Rat
	beta 2 Microglobulin Antibody (YA935) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA935), targeting beta 2 Microglobulin, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). beta 2 Microglobulin Antibody (YA935) can be used for WB, IP experiment in human, mouse, rat background.

HY-P83265

	beta II Tubulin Antibody (YA3010) class II beta tubulin isotype; beta2; Tubulin beta 2 chain; TUBB; TUBB2	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	beta II Tubulin Antibody (YA3010) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3010), targeting beta II Tubulin, with a predicted molecular weight of 50 kDa (observed band size: 50 kDa). beta II Tubulin Antibody (YA3010) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P82013

	*GABA A Receptor beta 2* Antibody (YA1758)** GABA; GABA(A) receptor beta 2; GABA(A) receptor subunit beta-2; GABRB2	WB	Human, Mouse, Rat
	GABA A Receptor beta 2 Antibody (YA1758) is a biotin-conjugated non-conjugated IgG antibody, targeting GABA A Receptor beta 2, with a predicted molecular weight of 59 kDa (observed band size: 59 kDa). GABA A Receptor beta 2 Antibody (YA1758) can be used for WB experiment in human, mouse, rat background.

HY-P81769

	S6K2 Antibody (YA1514) RPS6KB2; STK14B; Ribosomal protein S6 kinase beta-2; S6K-beta-2; S6K2; 70 kDa ribosomal protein S6 kinase 2; P70S6K2; p70-S6K 2; S6 kinase-related kinase; SRK; Serine/threonine-protein kinase 14B; p70 ribosomal S6 kinase beta; S6K-beta; p70	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	S6K2 Antibody (YA1514) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1514), targeting S6K2, with a predicted molecular weight of 53 kDa (observed band size: 53 kDa). S6K2 Antibody (YA1514) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, mouse, rat background.

HY-P82022

	PSMB10 Antibody (YA1767) LMP10; MECL1; beta2i	WB	Human, Rat
	PSMB10 Antibody (YA1767) is a biotin-conjugated non-conjugated IgG antibody, targeting PSMB10, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). PSMB10 Antibody (YA1767) can be used for WB experiment in human, rat background.

HY-P80189A

	IL-6 Antibody (YA3428) Interleukin BSF 2; BSF 2; BSF-2; CDF; CTL differentiation factor antibody; HGF; HSF; IFN-beta-2; IFNB2; IL 6; IL-6	WB, ICC/IF	Mouse, Rat
	IL-6 Antibody (YA724) is a non-conjugated and Mouse origined monoclonal antibody about 24 kDa, targeting to IL-6. It can be used for WB, IF-Cell assays with tag free, in the background of Rat, Mouse.

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Cat. No.	Product Name		Classification

HY-142118A

Trabedersen sodium AP 12009 sodium		Antisense Oligonucleotides
Trabedersen sodium is an antisense oligodeoxynucleotide that specifically inhibits *TGF-β2* (TGF-beta/Smad). Trabedersen sodium can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon ^[2].

HY-158821

ISTH0036		Antisense Oligonucleotides
ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), can be use in the study of primary open angle glaucoma (POAG), and wet age-related macular degeneration.

HY-158821A

ISTH0036 sodium		Antisense Oligonucleotides
ISTH0036 sodium, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), can be use in the study of primary open angle glaucoma (POAG) , and wet age-related macular degeneration.

HY-142118

Trabedersen AP 12009		Antisense Oligonucleotides
Trabedersen (AP 12009) is an antisense oligodeoxynucleotide that specifically inhibits *TGF-β2* (TGF-beta/Smad). Trabedersen can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon ^[2].

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