2. Search Result
Search Result
Results for "

Melanoma

" in MedChemExpress (MCE) Product Catalog:

400

Inhibitors & Agonists

1

Fluorescent Dye

4

Biochemical Assay Reagents

33

Peptides

15

Inhibitory Antibodies

92

Natural
Products

22

Recombinant Proteins

7

Isotope-Labeled Compounds

11

Antibodies

4

Oligonucleotides

Species:
Tag:
Source:
Cat. No. Compare Product Name Species Source
  • HY-P72258
    Melanoma antigen preferentially/PRAME, Human (His)

    CT130; MAPE; OIP4; OPA interacting protein 4

    		 Human E. coli
    PRAME is located in the CRL2 E3 ubiquitin-protein ligase complex and directs ubiquitination and degradation, specifically targeting the truncated MSRB1/SEPX1 selenoprotein.It is recruited to active promoter regions and is involved in chromatin regulation.Melanoma antigen preferentially/PRAME, Human (His) is the recombinant human-derived Melanoma antigen preferentially/PRAME, expressed by E.coli , with N-6*His labeled tag.
  • HY-P70846
    MIA Protein, Human (His)

    Melanoma-Derived Growth Regulatory Protein; Melanoma Inhibitory Activity Protein; MIA

    		 Human E. coli
    MIA proteins exhibit significant growth inhibitory effects on melanoma cells in vitro, extending their effects to various neuroectodermal tumors such as gliomas. In addition to playing an inhibitory role in cell growth, MIA proteins are also involved in molecular interactions, interacting with FASLG and TMIGD2. MIA Protein, Human (His) is the recombinant human-derived MIA protein, expressed by E. coli , with C-6*His labeled tag. The total length of MIA Protein, Human (His) is 107 a.a., with molecular weight of ~14.0 kDa.
  • HY-P70846A
    MIA Protein, Human (N-His)

    Melanoma-Derived Growth Regulatory Protein; Melanoma Inhibitory Activity Protein; MIA

    		 Human E. coli
    MIA proteins exhibit significant growth inhibitory effects on melanoma cells in vitro, extending their effects to various neuroectodermal tumors such as gliomas. In addition to playing an inhibitory role in cell growth, MIA proteins are also involved in molecular interactions, interacting with FASLG and TMIGD2. MIA Protein, Human (N-His) is the recombinant human-derived MIA protein, expressed by E. coli , with N-6*His labeled tag. The total length of MIA Protein, Human (N-His) is 107 a.a., with molecular weight of ~14.0 kDa.
  • HY-P71649
    GSDMC Protein, Human (His-SUMO)

    Gasdermin C; Gasdermin-C; GSDMC; Melanoma derived leucine zipper, extra nuclear factor; Melanoma-derived leucine zipper-containing extranuclear factor; MLZE

    		 Human E. coli
    GSDMC protein serves as the precursor of pore-forming proteins and undergoes cleavage to release Gasdermin-C. This N-terminal moiety binds to the membrane, forming pores with an inner diameter of 10 to 15 nm and inducing pyroptosis. GSDMC Protein, Human (His-SUMO) is the recombinant human-derived GSDMC protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of GSDMC Protein, Human (His-SUMO) is 508 a.a., with molecular weight of ~73.7 kDa.
  • HY-P7212
    IL-19 Protein, Human
    1 Publications Verification

    rHuIL-19; Melanoma differentiation association like protein; ZMDA1

    		 Human E. coli
    IL-19 Protein, Human is a member of the Interleukin-10 family. The biological functions and clinical implications of Interleukin-19 is still undefined.
  • HY-P700109AF
    Animal-Free IL-19 Protein, Human (His)

    Melanoma differentiation association like protein; ZMDA1

    		 Human E. coli
    Animal-Free IL-19 Protein, Human (His) is the recombinant human-derived animal-FreeIL-19 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-19 Protein, Human (His) is 154 a.a., with molecular weight of ~18.69 kDa.
  • HY-P7393
    Otoraplin/OTOR Protein, Human (CHO)

    rHuOTOR; Fibrocyte-derived protein; Melanoma inhibitory activity-like protein; OTOR; MIAL

    		 Human CHO
    Otoraplin/OTOR Protein, Human (CHO) is a protein encoded by OTOR gene, is homologous to the protein encoded by CDRAP/MIA, and may acts in cartilage development and maintenance.
  • HY-P702186
    AIM2 Protein, Human

    AIM2; Interferon-inducible protein AIM2; Absent in Melanoma 2

    		 Human E. coli
    AIM2 protein is a key sensor in the AIM2 inflammasome, which can activate the inflammasome in response to cytoplasmic dsDNA, thereby inducing pyroptosis. This complex is triggered by pathogens or injury signals and plays a critical role in innate immunity and inflammation. AIM2 Protein, Human is the recombinant human-derived AIM2 protein, expressed by E. coli , with tag free. The total length of AIM2 Protein, Human is 200 a.a., .
  • HY-P702187
    AIM2 Protein, Human (His)

    AIM2; Interferon-inducible protein AIM2; Absent in Melanoma 2

    		 Human E. coli
    AIM2 protein is a key sensor in the AIM2 inflammasome, which can activate the inflammasome in response to cytoplasmic dsDNA, thereby inducing pyroptosis. This complex is triggered by pathogens or injury signals and plays a critical role in innate immunity and inflammation. AIM2 Protein, Human (His) is the recombinant human-derived AIM2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of AIM2 Protein, Human (His) is 200 a.a., .
  • HY-P72816
    AIM2 Protein, Human (sf9, GST)

    Interferon-inducible protein AIM2; Absent in Melanoma 2; AIM2

    		 Human Sf9 insect cells
    AIM2 Protein, a member of the IFI20X/IFI16 family, exhibits potential regulatory functions in cell proliferation and tumorigenic reversion. Induced by interferon-gamma, AIM2 plays a key role in immune responses. Notably expressed in tissues like lymph node and appendix, AIM2 is a significant player in diverse cellular processes and immune-related functions. AIM2 Protein, Human (sf9, GST) is the recombinant human-derived AIM2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of AIM2 Protein, Human (sf9, GST) is 343 a.a., with molecular weight of ~65.2 kDa.
  • HY-P700420
    MAGEA4 Protein, Human (HEK293, His)

    MAGEA4; Melanoma antigen family A, 4; MAGE4; Melanoma-associated antigen 4; cancer/testis antigen family 1; member 4; CT1.4; MAGE 41; MAGE X2; MAGE4A; MAGE4B; Melanoma associated antigen 4; MGC21336

    		 Human HEK293
    MAGEA4 protein critically regulates cell proliferation by inhibiting G1 phase arrest and negatively modulates p53-mediated apoptosis. Its role in controlling key checkpoints emphasizes its impact on cellular homeostasis, suggesting significance in averting aberrant cell growth. MAGEA4 Protein, Human (HEK293, His) is the recombinant human-derived MAGEA4 protein, expressed by HEK293, with C-10*His labeled tag. The total length of MAGEA4 Protein, Human (HEK293, His) is 317 a.a., with molecular weight of 36.7 kDa.
  • HY-P77003
    IL-24 Protein, Human (HEK293, His)

    Interleukin-24; Melanoma differentiation-associated gene 7 protein; MDA-7; ST16

    		 Human HEK293
    Interleukin-24 (IL-24) belongs to the IL10 family of cytokines that selectively induces apoptosis in cancer cells and is recognized during melanoma cell differentiation. IL-24 overexpression increases the expression of GADD family genes and induces cell apoptosis. IL-24 Protein, Human (HEK293, His) is the recombinant human-derived IL-24 protein, expressed by HEK293 , with C-10*His labeled tag.
  • HY-P77004
    IL-24 Protein, Human (HEK293, Fc)

    Interleukin-24; Melanoma differentiation-associated gene 7 protein; MDA-7; ST16

    		 Human HEK293
    IL-24 protein, produced by T-cells, regulates immune responses, tissue homeostasis, defense, and oncogenesis. It induces type I interferon response in influenza infection, signaling through IL20RA/IL20RB or IL20RB/IL22RA1 receptor complexes to stimulate JAK1-STAT3 and MAPK pathways. IL-24 promotes secretion of IL8 and MMP1, maintains ER homeostasis, and serves as a quality control mechanism for the ubiquitin proteasome system. IL-24 Protein, Human (HEK293, Fc) is the recombinant human-derived IL-24 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of IL-24 Protein, Human (HEK293, Fc) is 155 a.a., with molecular weight of ~44.6 KDa.
  • HY-P700115AF
    Animal-Free IL-24 Protein, Human (His)

    Interleukin-24; Melanoma differentiation-associated gene 7 protein; MDA-7; ST16

    		 Human E. coli
    IL-24 protein, produced by T-cells, regulates immune responses, tissue homeostasis, defense, and oncogenesis. It induces type I interferon response in influenza infection, signaling through IL20RA/IL20RB or IL20RB/IL22RA1 receptor complexes to stimulate JAK1-STAT3 and MAPK pathways. IL-24 promotes secretion of IL8 and MMP1, maintains ER homeostasis, and serves as a quality control mechanism for the ubiquitin proteasome system. Animal-Free IL-24 Protein, Human (His) is the recombinant human-derived animal-FreeIL-24 protein, expressed by E. coli , with C-His labeled tag.
  • HY-P700570
    CDKN1A Protein, Human (GST)

    CDK-interacting protein 1Melanoma differentiation-associated protein 6 ; MDA-6p21

    		 Human E. coli
    The CDKN1A protein critically controls cell cycle progression and mediates DNA damage-induced G2 arrest through p53/TP53-dependent and CREB3L1-mediated p53-independent pathways. It inhibits cyclin-dependent kinase activity, blocking cell cycle progression by preventing phosphorylation of key substrates. CDKN1A Protein, Human (GST) is the recombinant human-derived CDKN1A protein, expressed by E. coli , with N-GST labeled tag. The total length of CDKN1A Protein, Human (GST) is 163 a.a., with molecular weight of 45 kDa.
  • HY-P71544
    MLANA Protein, Human (His, B2M)

    Antigen LB39 AA; Antigen LB39-AA; Antigen SK29 AA; Antigen SK29-AA; MAR1_HUMAN; MART 1; MART-1; MART1; Melan A; Melan A protein; Melanoma antigen recognized by T cells 1; Melanoma antigen recognized by T-cells 1; MLAN A; MLANA; OTTHUMP00000021036; OTTHUMP00000021037; OTTHUMP00000021038; Protein Melan-A

    		 Human E. coli
    The MLANA protein is essential in melanosome biosynthesis, ensuring the stability of GPR143, and plays a key role in the expression, stability, transport, and processing of the melanocyte protein PMEL. Its interaction with PMEL and GPR143 highlights its integral role in the complex network required for second-stage melanosome formation. MLANA Protein, Human (His, B2M) is the recombinant human-derived MLANA protein, expressed by E. coli , with N-His, B2M labeled tag.
  • HY-P700200AF
    Animal-Free IL-24 Protein, Mouse (His)

    Interleukin-24; IL-4-induced secreted protein; Melanoma differentiation-associated gene 7 protein (MDA-7); Th2-specific cytokine FISP; Il24; Mda7

    		 Mouse E. coli
    IL-24 Protein, a crucial immune regulatory cytokine, plays a pivotal role in modulating immune responses. Animal-Free IL-24 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-24 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-24 Protein, Mouse (His) is 155 a.a., with molecular weight of ~18.94 kDa.
  • HY-P71014
    Syntenin-1 Protein, Human (C-His)

    Syntenin-1; Melanoma differentiation-associated protein 9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; Scaffold protein Pbp1; Syndecan-binding protein 1; SDCBP; MDA9; SYCL;

    		Human E. coli
    Syntenin-1 is a multifunctional adapter protein that coordinates multiple cellular processes, including transmembrane protein trafficking, neural and immune regulation, exosome biogenesis, and tumorigenesis. It actively regulates TGFB1 signaling and enhances SMAD2/3 activation, TGFB1-induced epithelial-mesenchymal transition (EMT), and cell migration. Syntenin-1 Protein, Human (C-His) is the recombinant human-derived Syntenin-1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of Syntenin-1 Protein, Human (C-His) is 297 a.a., with molecular weight of ~ 32.0 kDa.
  • HY-P71014A
    Syntenin-1 Protein, Human (N-His)

    Syntenin-1; Melanoma differentiation-associated protein 9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; Scaffold protein Pbp1; Syndecan-binding protein 1; SDCBP; MDA9; SYCL;

    		Human E. coli
    Syntenin-1 protein is known to mediate Syndecan signaling and has a PDZ domain that binds transmembrane proteins. It affects cytoskeletal membrane organization, cell adhesion, protein trafficking, and transcription factor activation. Syntenin-1 Protein, Human (N-His) is the recombinant human-derived Syntenin-1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Syntenin-1 Protein, Human (N-His) is 298 a.a., with molecular weight of ~32 kDa.
  • HY-P700558
    GRO-alpha/CXCL1 Protein, Human (His)

    Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1

    		 Human E. coli
    GRO-alpha/CXCL1 protein attracts neutrophils and potentially contributes to inflammation through autocrine effects on endothelial cells. Processed forms of GRO-alpha, including GRO-alpha(4-73), GRO-alpha(5-73), and GRO-alpha(6-73), exhibit 30-fold greater chemotactic activity than the full-length protein. GRO-alpha/CXCL1 Protein, Human (His) is the recombinant human-derived GRO-alpha/CXCL1 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P700559
    GRO-alpha/CXCL1 Protein, Mouse (His)

    Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1

    		 Mouse E. coli
    GRO-alpha (CXCL1) Protein, with chemotactic properties, attracts and activates neutrophils during inflammatory responses. This hematoregulatory chemokine also suppresses hematopoietic progenitor cell proliferation, emphasizing its intricate role in hematopoiesis regulation. The truncated form KC(5-72) notably exhibits significantly enhanced hematopoietic activity in vitro. GRO-alpha/CXCL1 Protein, Mouse (His) is the recombinant mouse-derived GRO-alpha/CXCL1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GRO-alpha/CXCL1 Protein, Mouse (His) is 68 a.a., with molecular weight of 11.5 kDa.
  • HY-P70508
    GRO-alpha/CXCL1 Protein, Human (HEK293, His)
    1 Publications Verification

    Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1

    		 Human HEK293
    CXCL1 (Chemokine (C-X-C motif) ligand 1), also known as GRO alpha, NAP-3 or MGSA, belongs to the sub-family of CXC chemokine. CXCL1 is involved in the development of many inflammatory diseases, including the induction of angiogenesis and recruitment of neutrophils. CXCL1 is produced by many cell types, and activates CXCR2 and, at high levels, CXCR1. GRO-alpha/CXCL1 Protein, Human (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 73 amino acids (A35-N107).

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: