2. Gene
  3. Mb - myoglobin Gene

Mb - myoglobin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 17189 | Gene type: protein coding

About Mb

Summary

Predicted to enable oxygen binding activity. Acts upstream of or within several processes, including brown fat cell differentiation; enucleate erythrocyte differentiation; and response to hypoxia. Is expressed in brown fat; heart; skeletal muscle; and somite. Human ortholog(s) of this gene implicated in acute kidney failure. Orthologous to human MB (myoglobin). [provided by Alliance of Genome Resources, Apr 2022]

Mb Products(3)

mRNA Protein Name
NM_001164047.1 NP_001157519.1 myoglobin
NM_001164048.1 NP_001157520.1 myoglobin
NM_013593.3 NP_038621.2 myoglobin
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within brown fat cell differentiation IDA
IDA: Inferred from direct assay
18492766 MGI
acts upstream of or within enucleate erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
14656764 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
11304494 MGI
acts upstream of or within response to hypoxia IMP
IMP: Inferred from mutant phenotype
14656764 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myoglobin

Recombinant Mb Proteins

Cat. No. Product Name Accession Purity
HY-P71754 Myoglobin Protein, Mouse (P.pastoris, His) P04247 (2G-154G) ≥95%

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109523 Cerivastatin sodium 99.89% Unkown
HY-14197 Clorgyline Inhibitor 99.76% Unkown
Clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Phase
HY-15518 LCL161 Inhibitor 99.91% Phase 2
HY-101567 BMS-986158 Inhibitor 99.75% Phase 2
HY-145652 Narmafotinib Inhibitor 99.86% Phase 2
HY-139577A Ninerafaxstat trihydrochloride 99.65% Phase 2
HY-E70007 Catechol O-methyltransferase, porcine liver / Phase 2
HY-11038B Zelavespib hydrochloride Inhibitor 98.89% Phase 2
HY-16309 MB-07803 Inhibitor / Phase 2
HY-109071 Relmapirazin / Phase 2
Pre-clinical Phase
Bioactive Molecules (281)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0431 Astragaloside IV Inhibitor 99.93% Unkown
HY-139665 VB124 Inhibitor 99.86% Unkown
HY-129039 Butyrolactone 3 Inhibitor 99.31% Unkown
HY-112842 MBQ-167 Inhibitor 99.86% Unkown
HY-12810 EHop-016 Inhibitor 99.85% Unkown
HY-115467 MitoBloCK-10 98.89% Unkown
HY-15985 CTX-0294885 Inhibitor 98.44% Unkown
HY-B1816 Zaprinast 99.95% Unkown
HY-100753 STAT3-IN-1 97.47% Unkown
HY-16307 MB05032 Inhibitor 99.66% Unkown
HY-N0448 10-Gingerol 99.66% Unkown
HY-13808 UNC 0631 Inhibitor 98.35% Unkown
HY-11038 Zelavespib Inhibitor 99.93% Yes
HY-153910 AGPS-IN-1 99.74% Unkown
HY-149898 HA-CD44 interaction inhibitor 1 Inhibitor 98.93% Unkown
HY-13807 UNC0646 Inhibitor 99.38% Unkown
HY-117154 INH154 99.89% Unkown
HY-146751 PI3K/Akt/mTOR-IN-2 99.86% Unkown
HY-N1231 Sophoraflavanone G Inducer 99.52% Unkown
HY-102069 3MB-PP1 Inhibitor 98.53% Unkown
HY-120373 MB710 98.76% Unkown
HY-104051 Monacolin J Inhibitor 99.22% Unkown
HY-110243 CAIX Inhibitor S4 Inhibitor 99.04% Unkown
HY-115903 HIF-1α-IN-2 Inhibitor 98.45% Unkown
HY-150233 Cys-McMMAF Inhibitor 99.91% Unkown
HY-155956 GM-90257 ≥99.0% Unkown
HY-110329 ML179 Agonist 99.83% Unkown
HY-139109 IR-783 Inducer 99.87% Unkown
HY-108317 ABL127 Inhibitor 99.91% Unkown
HY-129578 Asperphenamate ≥98.0% Unkown
HY-139659 ARD-61 99.68% Unkown
HY-155982 STAT3-IN-20 Inhibitor 99.83% Unkown
HY-112338 C188 Inhibitor ≥97.0% Unkown
HY-119257 ABT-100 98.18% Unkown
HY-149843 LC-MB12 99.23% Unkown
HY-132305 VEGFR-3-IN-1 Inhibitor 98.55% Unkown
HY-14955 Managlinat dialanetil Inhibitor 98.13% Unkown
HY-22024 5-Hydroxyflavone 99.83% Unkown
HY-114324 PROTAC PARP1 degrader Inhibitor 99.74% Unkown
HY-111288 MB-07811 Agonist 99.09% Unkown
HY-15985A CTX-0294885 hydrochloride 99.60% Unkown
HY-N2638 Ilexsaponin A Inhibitor 99.53% Unkown
HY-155309 LM-41 Inhibitor 99.82% Unkown
HY-100353 C12-Ceramide 99.60% Unkown
HY-123081 Eburicol Inhibitor ≥98.0% Unkown
HY-148450 eIF4A3-IN-16 Inhibitor 98.37% Unkown
HY-164388 Z-VAD 99.49% Unkown
HY-N0046 Notoginsenoside Fe 99.98% Unkown
HY-N8187 Eupalinolide O Inducer 99.89% Unkown
HY-W143216 Azure C / Unkown
HY-118594 Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate 99.79% Unkown
HY-108447 BC-11 hydrobromide Inhibitor ≥99.0% Unkown
HY-148446 eIF4A3-IN-12 Inhibitor 99.70% Unkown
HY-148452 eIF4A3-IN-18 Inhibitor 99.58% Unkown
HY-151388 hMAO-B/MB-COMT-IN-1 Inhibitor 98.04% Unkown
HY-156278 FB49 Inhibitor 99.76% Unkown
HY-159569 TfR-1-IN-1 Inhibitor 96.96% Unkown
HY-N3057 Pinostrobin chalcone 99.94% Unkown
HY-114324A rel-PROTAC PARP1 degrader Degrader 98.99% Unkown
HY-114979 Pyoluteorin 99.90% Unkown
HY-115903A HIF-1α-IN-2 hydrochloride Inhibitor 99.16% Unkown
HY-146324 PROTAC eEF2K degrader-1 98.64% Unkown
HY-148444 eIF4A3-IN-10 Inhibitor 97.87% Unkown
HY-156273 HDAC/JAK/BRD4-IN-1 Inhibitor 95.07% Unkown
HY-164064 Anticancer agent 230 Activator 99.97% Unkown
HY-N0247 Saikosaponin B1 Inhibitor 99.42% Unkown
HY-Y1045 Tetrabutylammonium hydrogensulfate ≥98.0% Unkown
HY-160899A Thailanstatin A cyclohexane diamine formic 93.74% Unkown
HY-129163 HJ-PI01 Inhibitor 99.72% Unkown
HY-131763 2'-O-MB-cAMP sodium 99.94% Unkown
HY-148443 eIF4A3-IN-9 Inhibitor 99.71% Unkown
HY-148445 eIF4A3-IN-11 Inhibitor 99.24% Unkown
HY-148447 eIF4A3-IN-13 Inhibitor 99.92% Unkown
HY-148448 eIF4A3-IN-14 Inhibitor 99.81% Unkown
HY-148449 eIF4A3-IN-15 Inhibitor / Unkown
HY-148451 eIF4A3-IN-17 Inhibitor 99.56% Unkown
HY-149636 Multi-target kinase inhibitor 2 Inhibitor 99.82% Unkown
HY-155113 PROTAC Hsp90α degrader 1 Degrader / Unkown
HY-157797 SN-38-CM2 / Unkown
HY-161096 Antitumor agent-127 99.09% Unkown
HY-161446 USP1-IN-7 Inhibitor 99.93% Unkown
HY-162352 SDU-071 Inhibitor 98.75% Unkown
HY-19513 MB-07344 Agonist 98.12% Unkown
HY-19513A MB-07344 sodium Agonist 99.07% Unkown
HY-N6990 Anhydrosecoisolariciresinol 99.94% Unkown
HY-P2799D Creatine Kinase MB (rCK-MB), Recombinant Human / Unkown
HY-11038D Zelavespib formic Inhibitor 97.39% Unkown
HY-16191 ELR510444 ≥98.0% Unkown
HY-W643128 Carlina oxide Inhibitor / Unkown
HY-107770 Duocarmycin MB / Unkown
HY-156403 AuM1Phe Inhibitor / Unkown
HY-101447 SI-2 / Unkown
HY-117093 H8-A5 / Unkown
HY-118820 MB-28767 Agonist / Unkown
HY-119331 CFM-5 Inducer / Unkown
HY-120275 CYD-2-11 / Unkown
HY-120421 SW116 free base / Unkown
HY-125958 AA9 Inhibitor / Unkown
HY-126005 VGSC blocker-1 Inhibitor / Unkown
HY-129458 Cerivastatin / Unkown
HY-131037 MB-0223 Inhibitor / Unkown
HY-131508 M&B 5124 Inhibitor / Unkown
HY-136289 MB-VC-MGBA / Unkown
HY-139376 FGFR1 inhibitor-2 Inhibitor / Unkown
HY-143293 VEGFR-IN-3 / Unkown
HY-143468 MEK-IN-5 / Unkown
HY-143877 NN-390 Inhibitor / Unkown
HY-143903 ZL-Pin13 Inhibitor / Unkown
HY-144306 ERα degrader 4 / Unkown
HY-144638 JMX0293 / Unkown
HY-144642 PARP-1-IN-1 Inhibitor / Unkown
HY-144699 ERRα antagonist-2 Antagonist / Unkown
HY-145860 PHGDH-IN-2 / Unkown
HY-146037 Aurora A inhibitor 2 / Unkown
HY-146103 Antiproliferative agent-7 Inducer / Unkown
HY-146203 FAK inhibitor 6 / Unkown
HY-146239 EGFR/HER2/TS-IN-2 Inhibitor / Unkown
HY-146283 LSD1-IN-18 Inhibitor / Unkown
HY-146284 LSD1-IN-19 Inhibitor / Unkown
HY-146285 LSD1-IN-20 Inhibitor / Unkown
HY-146452 Anticancer agent 57 Inducer / Unkown
HY-146511 Anticancer agent 41 / Unkown
HY-146516 Anticancer agent 42 / Unkown
HY-146676 UR-MB108 Inhibitor / Unkown
HY-146783 ZINC194100678 Inhibitor / Unkown
HY-146786 ZMF-10 / Unkown
HY-147101 SK-575-NEG Inhibitor / Unkown
HY-147556 SK3 Channel-IN-1 Modulator / Unkown
HY-147670 TPB15 / Unkown
HY-148368 CYD-4-61 / Unkown
HY-149033 Kobusine derivative-2 / Unkown
HY-149354 Aurora Kinases-IN-4 Inhibitor / Unkown
HY-149388 Anticancer agent 139 Inhibitor / Unkown
HY-149635 HIF-1α-IN-6 Inhibitor / Unkown
HY-149729 ICMT-IN-53 Inhibitor / Unkown
HY-150597 HDAC-IN-46 / Unkown
HY-150613 PARP1/BRD4-IN-2 / Unkown
HY-151390 hMAO-B/MB-COMT-IN-2 Inhibitor / Unkown
HY-151630 hCAIX-IN-16 Inhibitor / Unkown
HY-152945 Antiproliferative agent-22 Inhibitor / Unkown
HY-153272 Antitumor agent-93 / Unkown
HY-153932 NR-7h Degrader / Unkown
HY-155011 MB076 Inhibitor / Unkown
HY-155039 Antitumor agent-105 / Unkown
HY-155098 CNBCA Inhibitor / Unkown
HY-155127 Antiproliferative agent-33 Inhibitor / Unkown
HY-155146 Anticancer agent 146 Inducer / Unkown
HY-155180 FD2056 Inhibitor / Unkown
HY-155249 KGP591 Inhibitor / Unkown
HY-155350 Tubulin polymerization-IN-53 Inhibitor / Unkown
HY-155359 Tubulin polymerization-IN-55 Inhibitor 98.84% Unkown
HY-155766 PARP1-IN-14 / Unkown
HY-155787 SHR5428 Inhibitor / Unkown
HY-155965 VEGFR/PARP-IN-1 / Unkown
HY-155969 EGFR-IN-83 / Unkown
HY-156018 PI3Kα-IN-13 Inhibitor / Unkown
HY-156026 FAK-IN-11 Inhibitor / Unkown
HY-156077 anti-TNBC agent-2 Inhibitor / Unkown
HY-156096 HDAC3-IN-2 / Unkown
HY-156097 Anticancer agent 158 Inhibitor / Unkown
HY-156098 c-Met-IN-19 Inhibitor / Unkown
HY-156296 CDK9-Cyclin T1 PPI-IN-1 / Unkown
HY-156378 Aurora A inhibitor 3 Inhibitor / Unkown
HY-156402 AuM1Gly Inhibitor / Unkown
HY-156444 HDAC1/CDK7-IN-1 / Unkown
HY-156524 USP1-IN-5 Inhibitor / Unkown
HY-156525 USP1-IN-6 Inhibitor / Unkown
HY-157151 iPRMT1 Inhibitor / Unkown
HY-157210 CDK7-IN-26 Inhibitor / Unkown
HY-158059 DS-1-38 Inhibitor 99.60% Unkown
HY-158170 CDK7-IN-28 Inhibitor / Unkown
HY-158387 Anticancer agent 214 Inhibitor / Unkown
HY-158388 Anticancer agent 215 Inhibitor / Unkown
HY-158389 Anticancer agent 216 Inhibitor / Unkown
HY-158390 Anticancer agent 217 Inhibitor / Unkown
HY-158439 anti-TNBC agent-7 Modulator / Unkown
HY-158683 KIF18A-IN-11 Inhibitor / Unkown
HY-159119 hDHODH-IN-15 / Unkown
HY-159122 CA IX-IN-2 / Unkown
HY-159515 PBE-AMF / Unkown
HY-159576 O-Me Eribulin / Unkown
HY-159897 PAK4-IN-5 / Unkown
HY-159990 GPX4-IN-15 Inhibitor / Unkown
HY-160598 Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol Inhibitor / Unkown
HY-160682 EGFR/HER2-IN-12 Inhibitor / Unkown
HY-161151 RecQ helicase-IN-1 / Unkown
HY-161257 CDC20-IN-1 Inducer / Unkown
HY-161372 PARP1/c-Met-IN-1 / Unkown
HY-161517 PARP1-IN-20 Inhibitor / Unkown
HY-161687 Cisplatin/Dasatinib prodrug-1 Inhibitor / Unkown
HY-161755 Anticancer agent 232 / Unkown
HY-161769 HL435 / Unkown
HY-161770 HL389 / Unkown
HY-161778 ZG-126 / Unkown
HY-161855 VEGFR-2-IN-50 / Unkown
HY-161868 DLC-50 / Unkown
HY-161878 USP1-IN-10 Inhibitor / Unkown
HY-161995 FGFR1/VEGFR2-IN-2 / Unkown
HY-162012 HC-258 / Unkown
HY-162034 FAK-IN-17 Inhibitor / Unkown
HY-162046 Anticancer agent 178 Inducer / Unkown
HY-162531 KIF18A-IN-9 Inhibitor / Unkown
HY-162532 KIF18A-IN-10 Inhibitor / Unkown
HY-162575 Anticancer agent 231 / Unkown
HY-162614 Rogersonin E Inhibitor / Unkown
HY-162632 Hit 14 Inhibitor / Unkown
HY-162633 USP1-IN-9 / Unkown
HY-162640 ROR1-IN-1 Inhibitor / Unkown
HY-162643 Antitumor agent-169 Inhibitor / Unkown
HY-162645 BPR5K230 Inhibitor / Unkown
HY-162688 Anticancer agent 239 Inducer / Unkown
HY-162751 Anticancer agent 249 / Unkown
HY-162805 iNOS/TopoI-IN-1 Inhibitor / Unkown
HY-162826 Apoptosis inducer 27 Inducer / Unkown
HY-162868 c-Met/HDAC-IN-4 / Unkown
HY-16308 FBPase-IN-5 Inhibitor / Unkown
HY-16311 MB-7133 Inhibitor / Unkown
HY-163112 Anticancer agent 179 / Unkown
HY-163113 Anticancer agent 180 / Unkown
HY-163290 HDAC-MB Inhibitor / Unkown
HY-163369 HDAC6-IN-35 Inhibitor / Unkown
HY-163434 PRMT5/EGFR-IN-1 Inhibitor / Unkown
HY-163676 MI-217 / Unkown
HY-163709 PROTAC FAK degrader 2 Degrader / Unkown
HY-163760 ZM-32 Inhibitor / Unkown
HY-163845 YX862 Degrader / Unkown
HY-164320 Anticancer agent 245 / Unkown
HY-164349 WZ-2-033 Inhibitor / Unkown
HY-168029 eEF2K degrader-1 Degrader / Unkown
HY-168037 PROTAC PIN1 degrader-1 / Unkown
HY-168093 Cetzole Inducer / Unkown
HY-168106 ZMF-24 / Unkown
HY-168154 COMT-IN-2 Inhibitor / Unkown
HY-168650 ROCK/HDAC-IN-1 Inhibitor / Unkown
HY-168720 Apoptosis inducer 32 Inducer / Unkown
HY-169382 Melatonin-Tamoxifen Conjugate Inhibitor / Unkown
HY-169408 EGFR-IN-137 / Unkown
HY-D0312 Mordant Blue 13 / Unkown
HY-N0985 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone / Unkown
HY-N10965 Gambogic acid B / Unkown
HY-N12607 Garcilatelic acid / Unkown
HY-N13118 Sinopodophylline B / Unkown
HY-N2741 Vitexin B-1 Inhibitor / Unkown
HY-N7484 (−)-Voacangarine Inhibitor / Unkown
HY-N7507 Sempervirine Inhibitor / Unkown
HY-P10511 Pantinin-3 / Unkown
HY-P10760 PhAc-ALGP-Dox / Unkown
HY-P2799H Creatine kinase-MB, Human heart / Unkown
HY-RS08179 MB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08180 MB21D2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-U00002A ZD-4190 hydrochloride Inhibitor / Unkown
HY-116447 Antitumor agent-159 Inducer / Unkown
HY-116904 Anticancer agent 253 / Unkown
HY-119948 AKCI Modulator / Unkown
HY-123715 Anticancer agent 255 / Unkown
HY-131764 2'-O-MB-cGMP sodium Inhibitor / Unkown
HY-134395 6-MB-cAMP / Unkown
HY-134997 4-Oxo Docosahexaenoic Acid Agonist / Unkown
HY-137866 Tubulin inhibitor 9 Inhibitor / Unkown
HY-138210 N,O-Diacetyltyramine Inhibitor / Unkown
HY-139795 ZYJ-25e Inhibitor / Unkown
HY-139815 ZYJ-34c Inhibitor / Unkown
HY-14955A (Rac)-Managlinat dialanetil / Unkown
HY-149710 POP-3MB Inhibitor / Unkown
HY-149714 J6-3 Inhibitor / Unkown
HY-149715 R1-11 Inhibitor / Unkown
HY-161118 MB327 / Unkown
HY-161456 PHGDH-IN-5 Inhibitor / Unkown
HY-161773 HL389-NHC2-PEG3-C2NH / Unkown
HY-164306 PROTAC PARP1 degrader-2 Degrader / Unkown
HY-164401 QBS10072S / Unkown
HY-164500 MC3629 Inhibitor / Unkown
HY-164521 PMMB-187 Inhibitor / Unkown
HY-165421 Mps1-IN-10 Inhibitor / Unkown
HY-168326 Antiproliferative agent-64 Inhibitor / Unkown
HY-170527 Anticancer agent 260 / Unkown
HY-N13163 2-Epitripdiolide / Unkown
HY-P10393 ERα17p Inducer / Unkown
HY-W010713 Meso-tetraphenylchlorin / Unkown
HY-W369099 HJC0152 free base / Unkown
HY-W667666 Anthragallol 1,2-dimethyl ether / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mb NCBI NCBI:4151
Canis familiaris Mb NCBI NCBI:608715
Macaca fascicularis Mb NCBI NCBI:102132612
Canis lupus familiaris Mb NCBI
Susscrofa domestica Mb NCBI
Leporidae Mb NCBI
Rattus norvegicus Mb NCBI NCBI:59108
Macaca mulatta Mb NCBI NCBI:693269