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Results for "

PC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (2) ADC Linker (8) Adenosine Receptor (1) Adrenergic Receptor (5) Akt (6) AMPK (2) Amyloid-β (7) Anaplastic lymphoma kinase (ALK) (3) Androgen Receptor (4) Antibiotic (1) Apoptosis (59) Autophagy (4) Bacterial (20) Bcl-2 Family (2) Biochemical Assay Reagents (39) Bombesin Receptor (1) Btk (1) c-Met/HGFR (1) Calcium Channel (3) Calmodulin (2) Carbonic Anhydrase (1) Caspase (5) Cathepsin (1) CDK (5) Cholinesterase (ChE) (4) COMT (1) COX (2) Cytochrome P450 (2) DAGL (1) Dihydrofolate reductase (DHFR) (1) DNA/RNA Synthesis (5) Dopamine Receptor (1) Drug Derivative (3) Drug Intermediate (1) Drug Metabolite (1) Drug-Linker Conjugates for ADC (1) EGFR (13) Endogenous Metabolite (33) Epigenetic Reader Domain (9) ERK (1) Estrogen Receptor/ERR (1) Farnesyl Transferase (1) Fatty Acid Synthase (FASN) (3) Ferroptosis (2) Filovirus (1) Fluorescent Dye (3) Fungal (5) G Protein-coupled Receptor Kinase (GRK) (1) GABA Receptor (3) GLP Receptor (1) Glutaminase (1) Glutathione S-transferase (1) HDAC (2) Hedgehog (2) Histamine Receptor (1) Histone Acetyltransferase (2) Histone Demethylase (4) Histone Methyltransferase (1) HIV (1) HSP (3) Huntingtin (1) IAP (1) ICMT (3) iGluR (1) Imidazoline Receptor (3) Insecticide (1) Interleukin Related (4) IRAK (1) Isotope-Labeled Compounds (42) Itk (1) JAK (2) JNK (2) Keap1-Nrf2 (3) Liposome (26) mAChR (2) MAGL (1) MAP3K (1) MAP4K (1) MDM-2/p53 (3) MEK (1) Microtubule/Tubulin (4) Mitochondrial Metabolism (2) MMP (1) Monoamine Oxidase (4) mTOR (2) nAChR (5) NADPH Oxidase (1) Necroptosis (2) NF-κB (3) NO Synthase (1) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (3) p38 MAPK (2) Paraptosis (1) Parasite (5) PD-1/PD-L1 (1) Phosphatase (1) Phospholipase (5) PI3K (4) PI4K (1) Pim (5) PKA (2) PKC (6) Platelet-activating Factor Receptor (PAFR) (2) Polo-like Kinase (PLK) (1) Potassium Channel (1) PPAR (1) PROTAC Linkers (6) PROTAC-Linker Conjugates for PAC (1) PROTACs (12) Proteasome (1) PSMA (3) Radionuclide-Drug Conjugates (RDCs) (1) Raf (4) Ras (2) Reactive Oxygen Species (13) Reverse Transcriptase (1) ROCK (1) ROS Kinase (1) RSV (1) Scavenger Receptor Class B type I (SR-BI） (1) SGK (1) SGLT (1) Small Interfering RNA (siRNA) (5) Smo (2) SOD (1) Sodium Channel (7) SphK (1) Src (1) STAT (3) Survivin (1) Tau Protein (1) TNF Receptor (1) Topoisomerase (1) Transmembrane Glycoprotein (2) Trk Receptor (3) TRP Channel (7) VD/VDR (1) VEGFR (3) Wnt (1)
By Research Areas:	Cancer (176) Cardiovascular Disease (14) Endocrinology (3) Infection (25) Inflammation/Immunology (27) Metabolic Disease (44) Neurological Disease (61)
Click Chemistry:	ADC Synthesis (5) DBCO (2) PROTAC Synthesis (5) Azide (5) Tetrazine (1) Alkynes (4)
Oligonucleotides:	Liposomal Film-forming Agents (1) Emulsifiers (1) Phospholipids (42) Mouse Pre-designed siRNA Sets (1) Cationic Lipids (1) Human Pre-designed siRNA Sets (4) siRNAs (5)

408

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Pyruvate Carboxylase (PC)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-157544

PC5-VC-PAB-MMAE	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
PC5-VC-PAB-MMAE consists the ADCs linker (PC5-VC-PAB) and potent tubulin inhibitor (MMAE). PC5-VC-PAB-MMAE is a agent-linker conjugate for ADC .

HY-146331

PC190723	Bacterial	Infection
PC190723 is a bacterial cell division protein FtsZ inhibitor with an IC₅₀ of 55 ng/mL. PC190723 has bactericidal activity against B. subtilis and a variety of staphylococci, with MIC ranging from 0.5 and 1.0 μg/mL. PC190723 exerts antibacterial activity by enhancing FtsZ polymer assembly and inhibiting depolymerization .

HY-102038

PC786	RSV	Infection
PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A (IC₅₀ <0.09 to 0.71 nM) and RSV-B (IC₅₀, 1.3 to 50.6 nM) .

HY-112661

PC-766B Antibiotic PC-766B	Antibiotic Bacterial Fungal	Infection Cancer
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na ⁺, K ⁺-ATPase .

HY-120561

PC-046	Trk Receptor IRAK Pim Apoptosis	Cancer
PC-046 is a multi-target inhibitor for tyrosine receptor kinase B (TrkB), IRAK-4 and Pim-1, with IC₅₀ of 13.4 μM, 15.4 μM and 19.1 μM, respectively. PC-046 exhibits cytotoxicity against pancreatic cancer cell BxPC3 with IC₅₀ of 7.5-130 nM. PC-046 induces apoptosis and arrests cell cycle at G2/M phase in BxPC3. PC-046 exhibits antitumor efficacy and exhibits good pharmacokinetic characteristics in mice .

HY-123711

PC170942	Bacterial	Infection
PC170942, a PC58538 analogue, is a potent FtsZ protein inhibitor. PC170942 is a cell division inhibitor, and shows antibacterial activities .

HY-111396

PC58538	Bacterial	Infection
PC58538 is a cell division inhibitor, targeting to FtsZ. PC58538 shows moderate antibacterial activity, and inhibits cell division in vegetative cells of wild-type B. subtilis. PC58538 is also known to modulate the rate of GTP hydrolysis .

HY-157666

13:0 PC PC(13:0/13:0)	Endogenous Metabolite	Others
13:0 PC (PC(13:0/13:0)), also known as ditridecanoyl phosphatidyl choline (DTPC), is a phospholipid characterized by its unique structure that includes a polar head with a positively charged quaternary amine and a negatively charged phosphate, along with two non-polar fatty acid tails. This composition allows 13:0 PC to function effectively as a surfactant in mucus, while its amphiphilic nature makes it an essential component of cell membranes, particularly in endothelial cells, corneal epithelial cells, and fibroblasts. The liver synthesizes 13:0 PC, and it is also found in dietary sources such as eggs and soybeans. In addition, Avanti offers a diverse range of phosphatidylcholine products, including 13:0 PC, which are meticulously purified by HPLC to maintain their stability against oxidation and hydrolysis.

HY-157647

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC PC(18:0/22:4)	CDK Apoptosis	Cancer
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) is an inhibitor of cyclin-dependent kinases (CDKs).? 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC induces apoptosis and inhibits the growth of various cancer cell lines .

HY-159118

PC-Qz1	Bacterial	Infection
PC-Qz1 is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor with an IC₅₀ of 470 nM. PC-Qz1 has antibacterial activity .

HY-165157

1-1(Z)-Hexadecenyl-2-arachidonoyl-sn-glycero-3-PC 16:0p/20:4-PC; PC(P-16:0/20:4); C16(plasm)-20:4-PC	Biochemical Assay Reagents	Others
1-1(Z)-Hexadecenyl-2-arachidonoyl-sn-glycero-3-PC is a biochemical reagent.

HY-P3320

Phytochelatin 3 PC 3	Biochemical Assay Reagents	Others
Phytochelatin 3 (PC 3) is the small metal chelating peptide that can be used for chelating heavy metals .

HY-165997

1-1(Z)-Hexadecenyl-2-Palmitoyl-sn-glycero-3-PC PC-(P16:0/16:0)	Biochemical Assay Reagents	Metabolic Disease
1-1(Z)-Hexadecenyl-2-Palmitoyl-sn-glycero-3-PC is an ester product.

HY-117766

PC945	Fungal Cytochrome P450	Infection
PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC₅₀s of 0.23 μM and 0.22 μM, respectively .

HY-RS10111

PC Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PC Human Pre-designed siRNA Set A contains three designed siRNAs for PC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PC Human Pre-designed siRNA Set A PC Human Pre-designed siRNA Set A

HY-RS16637

pc Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
pc Mouse Pre-designed siRNA Set A contains three designed siRNAs for pc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

pc Mouse Pre-designed siRNA Set A pc Mouse Pre-designed siRNA Set A

HY-157698

1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PC C18(plasm)-20:4-PC; 18:0p/20:4-PC; PC(P-18:0/20:4)	Endogenous Metabolite	Metabolic Disease
1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively. It scavenges singlet oxygen in a cell-free assay.

HY-140138

PC SPDP-NHS carbonate ester	ADC Linker	Cancer
PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-140140

PC Mal-NHS carbonate ester	ADC Linker	Cancer
PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P3321A

Phytochelatin 4 TFA PC 4 TFA	Biochemical Assay Reagents	Others
Phytochelatin 4 (PC 4) TFA is a short Cys-rich peptide with repeating γ-Glu-Cys motifs found in plants .

HY-W704966

2-Stearoyl-sn-glycero-3-phosphocholine 18:0 Lyso-PC; LPC(18:0); PC(0:0/18:0)	Endogenous Metabolite	Metabolic Disease
2-Stearoyl-sn-glycero-3-PC is a lysophospholipid that contains stearic acid (HY-B2219) at the sn-2 position. It has been found in rabbit myocardium.

HY-138756

PC DBCO-PEG4-NHS ester	PROTAC Linkers	Cancer
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W020809

C18(Plasm) LPC PC(18:1p/0:0)	Endogenous Metabolite	Others
C18(Plasm) LPC (PC(18:1p/0:0)) is classified as a type of plasmalogen.

HY-140130

PC Biotin-PEG3-alkyne	ADC Linker	Cancer
PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140139

PC Alkyne-PEG4-NHS ester	ADC Linker	Cancer
PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140136

PC DBCO-PEG3-biotin	ADC Linker	Cancer
PC DBCO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC DBCO-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140863

PC-PEG11-Azide	PROTAC Linkers	Cancer
PC-PEG11-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC-PEG11-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-165663S

1-Myristoyl-d7-2-Linoleoyl-sn-glycero-3-PC 1-Myistoyl-d₇-2-Lioleoyl-s-glyceo-3-Phosphatidylcholie; 1-Myistoyl-d₇-2-Lioleoyl-s-glyceo-3-Phosphocholie; PC(14:0-d₇/18:2); 14:0-d₇/18:2-PC	Isotope-Labeled Compounds	Others
1-Myristoyl-d₇-2-Linoleoyl-sn-glycero-3-PC (1-Myistoyl-d₇-2-Lioleoyl-s-glyceo-3-Phosphatidylcholie, 1-Myistoyl-d₇-2-Lioleoyl-s-glyceo-3-Phosphocholie, PC(14:0-d₇/18:2), 14:0-d₇/18:2-PC) is deuterium labeled 1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC .

HY-140141

PC Methyltetrazine-PEG4-NHS carbonate ester	PROTAC Linkers	Cancer
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-140134

PC Biotin-PEG3-NHS ester	ADC Linker	Cancer
PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-140135

PC-Biotin-PEG4-NHS carbonate	PROTAC Linkers	Cancer
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-157695

1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine C18(Plasm)-22:6-PC; PC(P-18:0/22:6); 18:0p/22:6-PC	Endogenous Metabolite	Others
1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine (C18(Plasm)-22:6-PC) is a phospholipid identified in fish viscera by lipidomics strategy. It has different content and distribution in different fish species and can be used as an indicator of fish species differentiation.

HY-140132

PC Biotin-PEG3-azide	ADC Linker	Cancer
PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140142

PC Azido-PEG11-NHS carbonate ester	PROTAC Linkers	Cancer
PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Azido-PEG11-NHS carbonate ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-121195

Apalcillin PC-904	Bacterial	Infection
Apalcillin (PC-904) in combination with Ro 48-1220, a penam sulfone β-lactamase inhibitor, demonstrated broad-spectrum activity against gram-negative aerobic and anaerobic bacteria, excluding Klebsiella oxytoca. It exhibited potent activity against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with effective MICs (11 μg/mL). The combination also inhibited Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter species at low MICs (0.25 to 4 μg/mL). However, its efficacy against oxacillin-resistant staphylococci and certain gram-positive organisms was limited. Apalcillin/Ro 48-1220 showed comparable efficacy to piperacillin/tazobactam against some extended-spectrum β-lactamase-producing Escherichia coli but was less effective against SHV-type β-lactamases .

HY-W190937

PC Azido-PEG3-NHS carbonate ester	Biochemical Assay Reagents	Others
PC Azido-PEG3-NHS carbonate ester is a photocleavable linker. It can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

HY-W839203

22:0 PC 1,2-Didocosanoyl-sn-glycero-3-phosphocholine; PC(22:0/22:0)	Others Endogenous Metabolite	Others
22:0 PC (1,2-Didocosanoyl-sn-glycero-3-phosphocholine), a type of phosphatidylcholine, functions as a lung surfactant and is characterized as an amphipathic molecule predominantly found in the outer leaflets of biological membrane bilayers.

HY-156633

Rezatapopt PC14586	MDM-2/p53	Cancer
Rezatapopt (PC14586) is an orally active antineoplastic agent. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. Rezatapopt demonstrates tumor inhibition and regression in mouse models with established human tumor xenografts harboring the TP53 Y220C mutation .

HY-140133

PC-Biotin-PEG4-PEG3-azide	ADC Linker	Cancer
PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W753474

1,2-Dipalmitelaidoyl-sn-glycero-3-phosphocholine 1,2-DI9-trans-hexa-decenoyl-SN-glycero-3-phosphocholine; PC(16:1(9E)/16:1(9E))	Biochemical Assay Reagents	Metabolic Disease
1,2-Dipalmitelaidoyl-sn-glycero-3-phosphocholine (PC(16:1(9E)/16:1(9E))) is an ester product.

HY-W725327

1,2-Dipropionyl-sn-glycero-3-phosphocholine 1,2-Dipropionyl-sn-glycero-3-Phosphatidylcholine; 1,2-Dipropionyl-sn-glycero-3-Phosphocholine; PC(3:0/3:0)	Endogenous Metabolite	Metabolic Disease
1,2-Dipropionyl-sn-glycero-3-PC is a phospholipid containing propionic acid at the sn-1 and sn-2 positions. It has been used to study the interaction between water and the phosphocholine headgroup in aqueous solutions.

HY-141636

1-PalMitoyl-2-arachidoyllecithin 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine; PAPC; PC(16:0/20:4)	Endogenous Metabolite Biochemical Assay Reagents	Cardiovascular Disease
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells.

HY-W440983

SDPC PC(18:0/22:6); DHA-PC; 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine	PPAR	Cardiovascular Disease Cancer
SDPC (DHA-PC) is a new generation of omega-3 lipids, which contains an ester bond linking DHA at the sn-2 position of phospholipid. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine exerts anti-angiogenesis effect through activating PPARγ. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine significantly declines the proliferation, migration, tube formation of human umbilical vein endothelial cells. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine has the potential for anti-tumor angiogenesis research .

HY-19378

MIV-150 PC 815	HIV	Infection
MIV-150 is a nonnucleoside reverse transcriptase (NNRT) inhibitor, blocking HIV-1 and HIV-2 infections, with an EC₅₀<1 nM against HIV-1/HIV-2_MN.

HY-P3323

Phytochelatin 6 PC 6	Biochemical Assay Reagents	Others
Phytochelatin 6 is metal-binding compound produced by plants. Phytochelatin 6 may reduce bioavailability of dietary toxic metals such as cadmium .

HY-P3322

Phytochelatin 5 PC 5	Biochemical Assay Reagents	Others
Phytochelatin 5 is metal-binding compound produced by plants. Phytochelatin 5 may reduce bioavailability of dietary toxic metals such as cadmium .

HY-P3322A

Phytochelatin 5 TFA PC 5 TFA	Endogenous Metabolite	Others
Phytochelatin 5 TFA is metal-binding compound produced by plants. Phytochelatin 5 TFA may reduce bioavailability of dietary toxic metals such as cadmium .

HY-P3323A

Phytochelatin 6 TFA PC 6 TFA	Biochemical Assay Reagents	Others
Phytochelatin 6 TFA is metal-binding compound produced by plants. Phytochelatin 6 TFA may reduce bioavailability of dietary toxic metals such as cadmium .

HY-141636S

1-PalMitoyl-2-arachidoyllecithin-d9-1 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d₉-1; PAPC-d₉-1; PC(16:0/20:4)-d₉-1	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
1-PalMitoyl-2-arachidoyllecithin-d₉-1 (1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d₉-1) is deuterium labeled 1-PalMitoyl-2-arachidoyllecithin. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells .

HY-W725399

1,2-Dilignoceroyl-sn-glycero-3-phosphocholine DLiPC; PC24	Drug Intermediate Endogenous Metabolite	Others
1,2-Dilignoceroyl-sn-glycero-3-phosphocholine (DLiPC) is a long-chain diacyl phospholipid characterized by its C24 saturated hydrocarbon chains and serves as a significant precursor for eicosanoids.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W019833

MSPC PC(14:0/18:0); 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.

HY-130462

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC 2 Publications Verification POPC	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Liposome
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .

HY-N6601

Pomolic acid Randialic acid A	Triterpenes Structural Classification Euscaphis japonica other families Staphyleaceae Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Cancer	Apoptosis
Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from?Euscaphis japonica?(Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC) .

HY-N9410

Lysophosphatidylcholine 18:2 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC	Infection Structural Classification Natural Products Classification of Application Fields Source classification Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). Low plasma Lysophosphatidylcholine 18:2 also has been shown to predict impaired glucose tolerance, insulin resistance, type 2 diabetes, coronary artery disease, and memory impairment .

HY-13626

Spisulosine ES-285	Alkaloids Animals Classification of Application Fields Other Alkaloids Marine natural products Source classification Other marine organisms Disease Research Fields Cancer	PKC Apoptosis
Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation. Spisulosine induces apoptosis in PC-3 and LNCaP cells .

HY-112661

PC-766B Antibiotic PC-766B	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Fields Cancer	Antibiotic Bacterial Fungal
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na ⁺, K ⁺-ATPase .

HY-W127369

1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine PC(O-16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine is an endogenous metabolite present in Urine that can be used for the research of Obesity .

HY-130462R

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Standard)	Structural Classification Natural Products Microorganisms Source classification Plants	Liposome
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Standard) is the analytical standard of 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. This product is intended for research and analytical applications. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .

HY-N9257

8-Hydroxypinoresinol4,4'-di-O-β-D-glucopyranoside	Structural Classification Polysaccharides Source classification Plants Valerianaceae Valeriana amurensis Smir. ex Komarov Saccharides	Others
8-Hydroxypinoresinol4,4'-di-O-β-D-glucopyranoside (Compound 7) is a compound derived from roots and rhizomes. 8-Hydroxypinoresinol4,4'-di-O-β-D-glucopyranoside could prevent neurotoxicity in PC12 cells .

HY-N12124

Monascuspiloin Monascinol	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Akt mTOR AMPK Androgen Receptor Apoptosis Autophagy
Monascuspiloin (Monascinol) exhibits anti-androgenic activity with an IC₅₀ of 7 μM. Monascuspiloin inhibits viability of PC-3 and LNCaP with IC₅₀ of 45 and 47 μM. Monascuspiloin induces apoptosis in LNCaP through inhibition of Akt/mTOR signaling pathway, induces autophagy through activation AMPK signaling pathway and arrest cell cycle at G2/M phase in PC-3. Monascuspiloin exhibits antitumor efficacy in mice .

HY-N4029

Humulene oxide II	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	Others
Humulene oxide II is an essential oil component from Zingiber striolatum Diels flowers, leaves and stems. Humulene oxide II has cytotoxicity against A549, PC-3 and K562 cell lines .

HY-N9861

Kayaflavone	Ranunculus ternatus Thunb. Structural Classification Flavonoids Flavones Ranunculaceae Source classification Plants	Amyloid-β
Kayaflavone is an amentoflavone type biflavonoid. Kayaflavone has an inhibitory activity against amyloid-β42 cytotoxicity in PC-12 cells with an EC₅₀ value of 5.29 μΜ. Kayaflavone is promising for research of Alzheimer’s disease .

HY-113796

Kopsoffinol	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Kopsia pauciflora Hook.f. Plants	Others
Kopsoffinol, a bisindole alkaloid, shows in vitro growth inhibitory activity against human PC-3, HCT-116, MCF-7, and A549 cells and moderate effects in reversing multidrug-resistance in vincristine-resistant human KB cells .

HY-N3697

Demethoxydeacetoxypseudolaric acid B Deacetyldemethylpseudolaric acid B	other families Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Plants Disease Research Fields	Others
Demethoxydeacetoxypseudolaric acid B is a metabolite of the glucoside of pseudolaric acid C2 (PC2) .

HY-N7535

Chlorovaltrate K	Structural Classification Valeriana jatamansi Jones Iridoids Terpenoids Source classification Plants Valerianaceae	Others
Chlorovaltrate K is a chlorinated valepotriate with anticancer effects. Chlorovaltrate K shows moderate cytotoxicity against A549, PC-3M, HCT-8 and Bel 7402 cell lines with IC₅₀ values of 2.32-8.26 μM .

HY-N3544

Caryophyllene oxide (-)-Caryophyllene oxide	Structural Classification Hymenaea courbaril L. Classification of Application Fields Leguminosae Terpenoids Sesquiterpenes Source classification Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	Apoptosis Bacterial Fungal Parasite
Caryophyllene oxide ((-)-Caryophyllene oxide) is a bicyclic sesquiterpene with anticancer effects. Caryophyllene oxide induces apoptosis of PC-3 cells. Caryophyllene oxide shows analgesic and anti-inflammatory activities. Caryophyllene oxide has insecticidal, antioxidant, antimicrobial, antifungal, and antiparasitic properties .

HY-N10325

Sarbronine M	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Others
Scabronine M is a novel inhibitor of NGF-induced neurite outgrowth from PC12 cells.

HY-N7019

19-Hydroxybufalin	Classification of Application Fields Animals Source classification Disease Research Fields Steroids Cancer	Others
19-Hydroxybufalin is a bufadienolide, inhibits epithelial-mesenchymal transition and attenuates the migration and invasion of PC3 cells .

HY-N10687

Saprorthoquinone NSC 648341	Quinones Structural Classification Labiatae Source classification Plants Naphthalene Quinones Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	Others
Saprorthoquinone (NSC 648341) is a diterpenoid that can be found in salvia atropatana. Saprorthoquinone shows cytotoxicity for PC3 cells .

HY-121619

Jacaric acid	Structural Classification Caprifoliaceae Ketones, Aldehydes, Acids Source classification Plants Centranthus ruber (L.) DC	Apoptosis
Jacaric acid is a conjugated linolenic acid, which inhibits viability in cells PC-3 (IC₅₀ is 11.8 μM), LNCaP (IC₅₀ is 2.2 μM) and DLD-1, induces apoptosis and necrosis . Jacaric acid exhibits anticaner activity against prostate cancer and adenocarcinoma . Jacaric acid exhibits immunomodulating activity in murine peritoneal macrophages as an immunopotentiator . Jacaric acid is orally active.

HY-N12821

visamminol-3'-O-glucoside	Structural Classification Ophryosporus axilliflorus Hieron. Source classification Umbelliferae Plants Saccharides Monosaccharides	Others
Visamminol-3'-O-glucoside (Compound 4) is a chromone glycoside, which is initially isolated from Saposhnikovia divaricata. Visamminol-3'-O-glucoside exhibits weak cytotoxicity against cancer cells PC-3, SK-OV-3 and H460, with IC₅₀s of 93.91, >100 and >100 μM, respectively .

HY-N7972

19-Oxocinobufotalin	Structural Classification Animals Classification of Application Fields Source classification Disease Research Fields Steroids Cancer	Others
19-Oxocinobufotalin is capable of suppressing EMT (Epithelial-mesenchymal transition) and weakening the migratory and invasive potential of PC3 cells .

HY-N3544R

Caryophyllene oxide (Standard) (-)-Caryophyllene oxide (Standard)	Structural Classification Hymenaea courbaril L. Leguminosae Terpenoids Sesquiterpenes Source classification Plants Endogenous metabolite	Apoptosis Bacterial Fungal Parasite
Caryophyllene oxide (Standard) ((-)-Caryophyllene oxide (Standard)) is the analytical standard of Caryophyllene oxide (HY-N3544). This product is intended for research and analytical applications. Caryophyllene oxide is a bicyclic sesquiterpene with anticancer effects. Caryophyllene oxide induces apoptosis of PC-3 cells. Caryophyllene oxide shows analgesic and anti-inflammatory activities. Caryophyllene oxide has insecticidal, antioxidant, antimicrobial, antifungal, and antiparasitic properties.

HY-W778562

10-Deacetyl-13-oxobaccatin III	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus baccata L.	Others
10-Deacetyl-13-oxobaccatin III is an taxane that can be isolated from Taxus sumatrana. 10-Deacetyl-13-oxobaccatin III (30 μg/mL) shows cytotoxicity against A498, NCI-H226, A549, PC-3 cells, with inhibition a rate of 29.7%, 49.2%, 43.9%, 65.3% .

HY-N8103

Heishuixiecaoline A	Structural Classification Terpenoids Sesquiterpenes Source classification Valeriana amurensis Smir. ex Komarov Plants Valerianaceae	Amyloid-β
Heishuixiecaoline A is a germacrane-type sesquiterpenoid. Heishuixiecaoline A shows protective effect on the neurotoxicity of PC12 cells induced by Aβ_25-35 .

HY-N3563

Celaphanol A	Structural Classification Terpenoids Source classification Celastraceae Diterpenoids Celastrus Plants Celastrus orbiculatus Thunb.	Others
Celaphanol A is a diterpene that can be isolated from the root bark of Celastrus orbiculatus. Celaphanol A shows neuroprotective effect against a hydrogen peroxide-induced cytotoxicity in PC12 cells .

HY-N9085

Neuchromenin	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Neuchromenin is a microbial melabolite that can be isolated from the culture broth of Eupenicillium javanicum var. meloforme PFll81. Neuchromenin induces neurite outgrowth of PC12 cells .

HY-N11001

Erinacine U	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Terpenoids Source classification Diterpenoids Disease Research Fields	Others
Erinacine U is a cyanogen diterpene isolated from Hericium erinaceus, which has neurotrophic activity and has obvious neurite growth-promoting effect on PC12 cells .

HY-N12001

6-Epiagarotetrol	Structural Classification Natural Products Thymelaeaceae Source classification Plants Aquilaria sinensis (Lour.) Spreng.	Others
6-Epiagarotetrol is a neuroprotective agent can be extracted from Aquilaria sinensis. 6-Epiagarotetrol has a protective effect on corticosterone-induced PC12 cell damage .

HY-N3938

Gelsemiol	Structural Classification Iridoids Terpenoids Source classification Populus tomentosa Plants Salicaceae	Others
Gelsemiol is the main active ingredient in Verbena littoralis H. B. K.. Gelsemiol enhanced nerve growth factor (NGF) -induced axonal elongation in PC12D cells .

HY-N12004

19-Hydroxy-10-deacetylbaccatin III	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus chinensis (Pilger) Rehd.	Others
19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively .

HY-108016

Peruvoside Encordin	Apocynaceae Triterpenes Structural Classification Terpenoids Source classification Thevetia peruviana (Pers.) K. Schum. Plants	Src PI3K JNK STAT EGFR Apoptosis Autophagy
Peruvoside is a potent inhibitor of Src, PI3K, JNK, STAT, and EGFR. Peruvoside induces apoptosis and autophagy and possesses a broad spectrum of anticancer activity in breast, lung, liver cancers and leukemia. Peruvoside is a broad-spectrum and potent antiviral activity against positive-sense RNA viruses. Peruvoside sensitizes Gefitinib (HY-50895)-resistant tumour cells (A549, PC9/gef and H1975) to Gefitinib .

HY-N3550

Catalponol	Other Terpenoids Structural Classification Catalpa ovata G. Don Classification of Application Fields Terpenoids Source classification Bignoniaceae Plants Disease Research Fields Cancer	Others
Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells .

HY-111266

Halenaquinone	Structural Classification Natural Products Marine natural products Source classification Sponge	PI3K Apoptosis
Halenaquinone is a phosphatidylinositol 3-kinase inhibitor and can be isolated from the marine sponge Petrosia alfiani. Halenaquinone inhibits RANKL-induced osteoclastogenesis, and induces cell apoptosis in PC12 cells .

HY-N13772

3'-O-Methyltaxifolin (+)-Dihydroisorhamnetin	Structural Classification Flavanonols Flavonoids Pulicaria jaubertii E.Gamal-Eldin Source classification Asteraceae Plants	Apoptosis
3'-O-Methyltaxifolin ((+)-Dihydroisorhamnetin) is a dihydroflavanol found in Pulicaria jaubertii. A mixture of these alcohol compounds including 3'-O-Methyltaxifolin found in Pulicaria jaubertii exhibits antitumor activity with IC₅₀ values of 19.1 μg, 20.0 μg, and 24.1 μg against prostate cancer (PC-3), breast cancer (MCF-7), and hepatocellular carcinoma (HepG-2) cell lines, respectively. Furthermore, 3'-O-Methyltaxifolin can induce cell apoptosis, making it a promising candidate for anticancer research. .

HY-W437569

Melicopine	Structural Classification Alkaloids Cornaceae Cornus officinalis Sieb. et Zucc. Source classification Acridone Alkaloids Plants	Parasite Insecticide
Melicopine is an alkaloid found in Z. simulans with antimalarial and anticancer activities. It exhibits inhibitory activity against chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum, with IC₅₀ values of 29.7 and 33.7 µg/mL, respectively. Melicopine is cytotoxic to prostate cancer cells PC-3M and LNCaP (IC₅₀ values of 47.9 and 37.8 µg/mL), but has no effect on non-cancerous HEK293 cells (IC₅₀ greater than 100 µg/mL). Melicopine holds promise for research in anticancer and anti-infection fields .

HY-N12225

Isoasiaticoside	Triterpenes Structural Classification Polysaccharides Terpenoids Source classification Tagetes lucida Cav. Plants Umbelliferae Saccharides	Others
Isoasiaticoside is a pentacyclic triterpene saponin that can be isolated from Centella asiatica. Isoasiaticoside has potential neuroprotective effects in the 6-OHDA (HY-B1081)-induced PC12 cell model .

HY-N12170

Kissoone C	Structural Classification Terpenoids Sesquiterpenes Source classification Valeriana officinalis Linn. Plants Valerianaceae	Others
Kissoone C (compound 3) is a three-membered ring sesquiterpene isolated from valerian root. Kissoone C can enhance the activity of nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells .

HY-N12466

3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine	Structural Classification Alkaloids Microorganisms Source classification Indole Alkaloids	PKC p38 MAPK ROCK
3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine (Compound 7) is an inhibitor of protein kinases, with IC₅₀s of 0.092, 0.26, 0.77 μM for PKC-α, ROCK, ASK1. 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine shows potent cytotoxicity against PC-3 cancer cells with an IC₅₀ value of 0.16 μM .

HY-N3928

Garciniaxanthone E	Structural Classification Flavonoids Garcinia xanthochymus Hook. f. ex T. Anders. Flavonones Source classification Guttiferae Plants	Others
Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases .

HY-117517

NG-012	Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields Cancer	Trk Receptor
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .

HY-N2180

Pinoresinol dimethyl ether (+)-Eudesmin	Structural Classification Neurological Disease Classification of Application Fields Magnoliaceae Source classification Lignans Phenylpropanoids Magnolia biondii Pamp. Plants Disease Research Fields	PKC PKA
Pinoresinol dimethyl ether ((+)-Eudesmin) is a non-phenolic furofuran lignan isolated from Magnolia biondii with neuritogenic activity. Pinoresinol dimethyl ether ((+)-Eudesmin) can induce neuritis outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways .

HY-113253A

N8-Acetylspermidine dihydrochloride	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N8-Acetylspermidine dihydrochloride is a polyamine metabolite. N8-Acetylspermidine dihydrochloride can be oxidatively deaminated by copper amine oxidase. N8-Acetylspermidine dihydrochloride can also induce the differentiation of PC12 cells and promote neurite outgrowth .

HY-N3562

Cedrin	Structural Classification Cedrus deodara (Roxburgh) G. Don Flavonoids Neurological Disease Classification of Application Fields Pinaceae Flavonones Source classification Plants Disease Research Fields	Reactive Oxygen Species
Cedrin is a natural flavonoid that can be found in Cedrus deodara. Cedrin protects PC12 cells against neurotoxicity induced by Aβ1-42. Cedrin can reduce reactive oxygen species overproduction, increase the activity of superoxide dismutase and decrease malondialdehyde content .

HY-125125

Danshenxinkun D	Quinones Structural Classification Terpenoids Labiatae Samanea saman (Jacq.) Merr. Source classification Diterpenoids Plants Phenanthrenequinones	Dopamine Receptor
Danshenxinkun D is an anti-Alzheimer's disease (AD) candidate. Danshenxinkun D can significantly reverse the expression of PSEN1 and DRD2 mRNA in H₂O₂ treated PC12 cells. Danshenxinkun D can be used in the study of anti-Alzheimer's disease product candidate [1].

HY-N4285

Negletein 5,6-Dihydroxy-7-methoxyflavone	Structural Classification Flavonoids Flavones Labiatae Source classification Phenols Polyphenols Plants Medicago truncatula Gaertn.	NO Synthase TNF Receptor Interleukin Related
Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC₅₀ values of 16.4 and 10.8 μM, respectively .

HY-126359

1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine SLPC; 18:0-18:2 PC	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can be chosen as a model used to investigate the volatile compounds from oxidised phosphatidylcholine molecular species. This method is applied to a real food sample, i.e. soy lecithin .

HY-N3489

Isodihydrofutoquinol B	Structural Classification Source classification Piper wightii Miq. Lignans Piperaceae Phenylpropanoids Plants	Others
Isodihydrofutoquinol B (compound 9), an active compound, can be isolated from the stems of Piper kadsura (Choisy) Ohwi. Isodihydrofutoquinol B has A neuroprotective effect on Aβ25-35-induced PC12 cell damage with E₅₀ values of 3.06-29.3μM .

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-N12123

Peimisine 3-O-β-D-glucopyranoside	Structural Classification Alkaloids Liliaceae Other Alkaloids Source classification Plants Fritillaria unibracteata Hsiao et K. C. Hsia	Others
Peimisine 3-O-β-D-glucopyranoside (Compound 1) is a steroid alkaloid. Peimisine 3-O-β-D-glucopyranoside can be isolated and purified from natural Fritillaria unibracteata. Peimisine 3-O-β-D-glucopyranoside shows moderate protective effect on rotenone-induced neurotoxicity of PC12 cell line .

Cat. No.	Product Name	Chemical Structure

HY-138622S

24:0 Lyso PC-13C6
24:0 Lyso PC- ¹³C₆ is the ¹³C labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].

HY-146879S

26:0 Lyso PC-d4
26:0 Lyso PC-d₄ is deuterium labeled 26:0 Lyso PC.

HY-146895S

14:0 Lyso PC-d27
14:0 Lyso PC-d₂₇ is deuterium labeled 14:0 Lyso PC.

HY-146924S

16:0 (Rac)-PC-d80
16:0 (Rac)-PC-d₈₀ is deuterium labeled 16:0 (Rac)-PC.

HY-165663S

1-Myristoyl-d7-2-Linoleoyl-sn-glycero-3-PC
1-Myristoyl-d₇-2-Linoleoyl-sn-glycero-3-PC (1-Myistoyl-d₇-2-Lioleoyl-s-glyceo-3-Phosphatidylcholie, 1-Myistoyl-d₇-2-Lioleoyl-s-glyceo-3-Phosphocholie, PC(14:0-d₇/18:2), 14:0-d₇/18:2-PC) is deuterium labeled 1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC .

HY-141636S

1-PalMitoyl-2-arachidoyllecithin-d9-1

1-PalMitoyl-2-arachidoyllecithin-d₉-1 (1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d₉-1) is deuterium labeled 1-PalMitoyl-2-arachidoyllecithin. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells .

HY-138622S1

24:0 Lyso PC-d4
24:0 Lyso PC-d₄4 is the deuterium labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].

HY-143857S

22:0 Lyso PC-13C6
22:0 Lyso PC- ¹³C₆ is a ¹³C-labeled and deuterium labeled 22:0 Lyso PC[1].

HY-146841S

19:0 Lyso PC-d5
19:0 Lyso PC-d₅ is deuterium labeled 19:0 Lyso PC.

HY-146925S

15:0 Lyso PC-d5
15:0 Lyso PC-d₅ is deuterium labeled 15:0 Lyso PC.

HY-144086S

22:0 Lyso-PC-d4
22:0 Lyso-PC-d₄ is the deuterium labeled 22:0 Lyso-PC[1].

HY-146839S

17:0-16:1 PC-d5
17:0-16:1 PC-d₅ is deuterium labeled 17:0-16:1 PC.

HY-146850S

17:0-20:3 PC-d5
17:0-20:3 PC-d₅ is deuterium labeled 17:0-20:3 PC.

HY-146838S

17:0-18:1 PC-d5
17:0-18:1 PC-d₅ is deuterium labeled 17:0-18:1 PC.

HY-146840S

17:0-14:1 PC-d5
17:0-14:1 PC-d₅ is deuterium labeled 17:0-14:1 PC.

HY-146849S

17:0-22:4 PC-d5
17:0-22:4 PC-d₅ is deuterium labeled 17:0-22:4 PC.

HY-146891S

16:0-16:0 PC-d31
16:0-16:0 PC-d₃₁ is deuterium labeled 16:0-16:0 PC.

HY-146893S

18:0-18:0 PC-d35
18:0-18:0 PC-d₃₅ is deuterium labeled 18:0-18:0 PC.

HY-146880S

14:0-14:0 PC-d27
14:0-14:0 PC-d₂₇ is deuterium labeled 14:0-14:0 PC.

HY-139931S

1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC
1-Stearoyl-2-Arachidonoyl-d₈-sn-glycero-3-PC is the deuterium labeled 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC[1].

HY-146848S

C18(plasm)-18:1 PC-d9
C18(plasm)-18:1 PC-d₉ is deuterium labeled C18(plasm)-18:1 PC.

HY-130462S3

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d64
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d₆₂ (POPC-d₆₄) is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .

HY-130462S

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d31
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d₃₁ is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for

HY-130462S1

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d₈₂ is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for

HY-130462S2

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-13C16
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC- ¹³C₁₆ (POPC- ¹³C16) is ¹³C labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .

HY-167586S

18:0-22:6 PC-d9
18:0-22:6 PC-d₉ (1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine-d₉) is deuterium labeled 18:0-22:6 PC .

HY-N9410S

Lysophosphatidylcholine 18:2-d9
Lysophosphatidylcholine 18:2-d₉ is deuterium labeled Lysophosphatidylcholine 18:2. Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary

HY-167585S

16:0-18:2 PC-d5
16:0-18:2 PC-d₅ (1-palmitoyl-2-linoleoyl(d₅)-sn-glycero-3-phosphocholine) is deuterium labeled 16:0-18:2 PC .

HY-N11605S

C16(plasm)-18:1(d9) PC
C₁₆(plasm)-18:1(d₉) PC (1-(1Z-hexadecenyl)-2-oleoyl(d₉)-sn-glycero-3-phosphocholine) is deuterium labeled PC 16:0/18:1 .

HY-W040193S5

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₉ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glyc

HY-W040193S1

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₄ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly

HY-W040193S6

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₁₃ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly

HY-W040193S2

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₉ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly

HY-W040193S4

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₄ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glyc

HY-W040193S

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₀ is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

HY-W040193S3

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₈₃ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

HY-113123S1

LysoPC(14:0/0:0)-d7
LysoPC(14:0/0:0)-d₇ (14:0 Lyso PC-d₇) is deuterium labeled LysoPC(14:0/0:0). LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-13626S

Spisulosine-d3
Spisulosine-d₃ (ES-285-d₃) is deuterium labeled Spisulosine (HY-13626). Spisulosine is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation. Spisulosine induces apoptosis in PC-3 and LNCaP cells .

HY-B0021S

Doxifluridine-d2
Doxifluridine-d₂ is the deuterium labeled Doxifluridine[1]. Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.

HY-B0285AS

Amiloride-15N3 hydrochloride
Amiloride- ¹⁵N₃ (hydrochloride) is the ¹⁵N labeled Amiloride hydrochloride[1]. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC[2]) and urokinase-type plasminogen activator receptor (uTPA[3]). Amiloride hydrochloride is a blocker of polycystin-2 (PC2;TRPP2[4]) channel.

HY-17406S

Tolcapone-d7
Tolcapone-d₇ is a deuterium labeled Tolcapone. Tolcapone is a selective, potent and orally active COMT inhibitor. Tolcapone is also a potent inhibitor of α-syn and Aβ42 oligomerization and fibrillogenesis and protect against extracellular toxicity induced by the aggregation of both proteins in PC12 cells[1][2].

HY-B0285S

Amiloride-15N3
Amiloride- ¹⁵N₃ (MK-870- ¹⁵N₃) is ¹⁵N labeled Amiloride. Amiloride (MK-870) is an inhibitor of both epithelial sodium channel (ENaC ) and urokinase-type plasminogen activator receptor (uTPA ). Amiloride is a blocker of polycystin-2 (PC2; TRPP2 ) channel.

HY-W700834

Harman-d3

Harman-d₃ is deuterium labeled Harmane. Harmane is a benzodiazepine receptor inhibitor (IC₅₀=7 μM), with IC₅₀ values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane also inhibits haloperidol and serotonin, with IC₅₀ values of 163 μM and 101 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC₅₀=30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .

HY-W777360

Harman-13C2,15N

Harman- ¹³C₂, ¹⁵N is ¹³C and ¹⁵N labeled Harmane. Harmane is a benzodiazepine receptor inhibitor (IC₅₀=7 μM), with IC₅₀ values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane also inhibits haloperidol and serotonin, with IC₅₀ values of 163 μM and 101 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC₅₀=30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .

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