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Results for "

antifungal activities

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (146) Cardiovascular Disease (14) Endocrinology (3) Infection (580) Inflammation/Immunology (115) Metabolic Disease (26) Neurological Disease (21)
Oligonucleotides:	Nucleosides and their Analogs (1)

630

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

275

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2446

Kakuol	Fungal	Infection
Kakuol is a natural compound with antifungal activity .

HY-121615

α-Phellandrene alpha-Phellandrene	Fungal	Infection
α-Phellandrene (alpha-Phellandrene) has antifungal activity. α-Phellandrene significantly inhibits the hyphal growth of P. cyclopium, destroys their cell membrane integrity and causes leakage of cellular components .

HY-113560

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

HY-156252

Antifungal agent 75	Fungal	Infection
Antifungal agent 75 (compound 6r) is a potent antifungal agent against Candida albicans. Antifungal agent 75 significantly inhibits the formation of C. albicans biofilm, increases the permeability of the cell membrane, reduces the ergosterol level of the cell membrane, damages the membrane structure, and destroys the integrity of the cell structure to exert excellent antifungal activity .

HY-155761

Antifungal agent 71	Fungal	Infection
Antifungal agent 71 (compound 6r) is a trifluoromethyl pyrimidine derivative with antifungal activity. Antifungal agent 71 exhibits good in vitro antifungal activity against F. oxysporum, with the EC₅₀ value of 3.61 μg/mL .

HY-123077

Norsanguinarine	Fungal	Infection
Norsanguinarine, an alkaloid, has antifungal activity against Alternaria brassicicola, Curvularia maculans at 1000 ppm .

HY-B1852

Sulfometuron-methyl	Bacterial Fungal	Infection
Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III .

HY-N3088

Phaseollidin hydrate	Fungal	Infection
Phaseollidin hydrate is the hydrate form of the antimicrobial phytoalexin Phaseollidin, which has lower antifungal activity than the original Phaseollidin .

HY-151280

Antifungal agent 37	Bacterial Fungal	Infection
Antifungal agent 37 is a geterocyclic disulfide, with antifungal activity .

HY-B1852R

Sulfometuron-methyl (Standard)	Bacterial Fungal	Infection
Sulfometuron-methyl (Standard) is the analytical standard of Sulfometuron-methyl. This product is intended for research and analytical applications. Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III .

HY-161856

Antifungal agent 106	mTOR Fungal	Others
Antifungal agent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide against Monilinia fructicola. Antifungal agent 106 exhibits antifungal activity with an EC₅₀ value of 11.8 mg/L. It affects hyphal growth by disrupting cell membrane integrity, leading to increased membrane permeability and release of intracellular electrolytes. Antifungal agent 106 can be used in research related to brown rot of stone fruits .

HY-145407A

ent-Heronamide C	Fungal	Infection
ent-Heronamide C has antifungal activity and is designed as probe for the mode-of-action analysis of heronamide C .

HY-147919

Antifungal agent 33	Fungal	Infection
Antifungal agent 33 (compound 4e) is a potent *antifungal* agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC₅₀ of 0.19 μg/mL .

HY-156251

Antifungal agent 74	Fungal	Infection
Antifungal agent 74 (compound 3c) is a potent antifungal agent that displays excellent fungicidal activity against C. arachidicola and R. solani. Antifungal agent 74 exerts its fungicidal activity by disrupting steroid biosynthesis and ribosome biogenesis in eukaryotes .

HY-145407

16,17-Dihydroheronamide C	Fungal	Infection
16,17-Dihydroheronamide C has antifungal activity and is designed as probe for the mode-of-action analysis of heronamide C .

HY-126872

Nikkomycin I	Antibiotic Fungal	Infection
Nikkomycin I is a nucleoside peptide antibiotic found in Streptomyces tendae of the genus Streptomyces, with high antifungal, insecticidal, and acaricidal activities .

HY-139983

SDH-IN-1 1 Publications Verification	Fungal	Infection
SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against *S. sclerotiorum* (EC₅₀ of 0.14 mg/L) .

HY-N12805

α-Cadinol	Fungal Parasite	Infection
α-Cadinol is an antifungal agent that can inhibit the growth of Coriolus versicolor and Laetiporus sulfureus.α-Cadinol also possesses antimite activity .

HY-156338

Laccase-IN-2	Fungal	Infection
Laccase-IN-2 is an inhibitor of laccase. Laccase-IN-2 has excellent *antifungal* activity against Magnaporthe oryzae in vitro and in vivo .

HY-N10229

Harzianum A	Fungal Antibiotic	Infection
Harzianum A is a trichothecene that isolated from the soil-borne fungus Trichoderma harzianum. Harzianum A shows no cytotoxicity against baby hamster kidney cells, no activity against Gram-negative and Gram-positive bacteria, but modest antifungal activity at 100 μg/mL .

HY-W012349

2′-Hydroxychalcone	NF-κB Fungal Apoptosis Autophagy	Infection Cancer
2′-Hydroxychalcone is a hydroxyl derivative of chalcones with anticancer activities. 2'-Hydroxychalcone inhibits NF-κB pathway and induces autophagy and apoptosis in breast cancer cells . 2′-Hydroxychalcone shows a better antifungal activity against the complex Paracoccidioides spp .

HY-N3340

Macrocarpal I	Fungal	Infection
Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC₅₀ value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .

HY-N9930

Effusanin B	Fungal	Infection
Effusanin B (Compound 3) is a diterpenoid can be isolated from Rabdosia effusa (Maxim.) Hara. Effusanin B (Compound 3) has antifungal activity .

HY-148992

APX879	Calcineurin Fungal	Infection
APX879 is a fungal-specific calcineurin inhibitor that has less immunosuppressive activities and toxicities. APX879 is a C22-modified FK506 (HY-13756) analog, which maintains broad-spectrum antifungal activity .

HY-149067

Antifungal agent 47	Fungal	Infection
Antifungal agent 47 (compound 3b) shows the highest and broad-spectrum fungicidal activity, strong respiratory inhibition activity, and adenosine 5′-triphosphate synthesis inhibition activity. Antifungal agent 47 is potential as a fungicide .

HY-N0452

Hyperoside 4 Publications Verification	Influenza Virus Fungal NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-144121

Ph-Ph+	Bacterial Fungal Apoptosis	Infection Cancer
Ph-Ph+ is a hemiprotonic compound, which is produced from phenanthroline (ph) dimerization. Ph-Ph+ has antitumor, antibacterial and antifungal activities .

HY-N3488

Isodiospyrin	Topoisomerase Bacterial Fungal	Infection Cancer
Isodiospyrin, a natural dimeric naphthoquinone, is a human DNA topoisomerase I (Topoisomerase) inhibitor. Isodiospyrin can prevent both DNA relaxation and kinase activities of human topoisomerase I. Isodiospyrin shows anticancer, antibacterial and antifungal activities .

HY-163397

Antibacterial agent 196	Fungal	Infection
Antibacterial agent 196 (compound 6b) is a coumarin derivative containing oxime ether structure, and shows *antifungal* activity, with the EC₅₀ of 0.46 μg/mL against Rhizoctonia solani .

HY-143236

DHFR-IN-1	Bacterial Fungal	Infection
DHFR-IN-1 (compound 12) is a potent and selective DHFR (dihydrofolate reductase)inhibitor, with an IC₅₀ of 40.71 nM. DHFR-IN-1 exhibits promising antibacterial activity against gram-positive and gram-negative bacteria. DHFR-IN-1 exhibits moderate antifungal activities. DHFR-IN-1 exhibits a high synergistic effect with Levofloxacin (HY-B0330), where the FIC (fractional inhibitory concentration index) value is 0.249 .

HY-146060

Antibacterial agent 100	Bacterial Fungal	Infection
Antibacterial agent 100 (Compound 7c) is an antibacterial and antifungal agent. Antibacterial agent 100 shows promising activity with MIC values of 4, 4 and 8 μg/mL against Staphylococcus aureus, Candida albicans and Cryptococcus neoformans, respectively .

HY-W037200

2,3,5-Tri-O-benzyl-D-ribose 2,3,5-Tri-O-benzyl-D-ribofuranose	Fungal	Infection
2,3,5-Tri-O-benzyl-D-ribose (Compound 1) is an effective inhibitor of Botrytis cinerea chitin synthase (CHS) with an IC₅₀ value of 1.8 μM. 2,3,5-Tri-O-benzyl-D-ribose exhibits antifungal activity and is able to inhibit the B. cinerea BD90 strain, with a MIC value of 190 μM .

HY-158321

SDH-IN-15	Fungal Succinate Dehydrogenase	Infection
SDH-IN-15 (Compound 5e) is an inhibitor of succinate dehydrogenase (SDH) (IC₅₀=2.04 μM). SDH-IN-15 has significant antifungal activity. SDH-IN-15 blocks the mitochondrial respiratory chain of the fungus through inhibition of SDH, resulting in fungal death .

HY-N0452R

Hyperoside (Standard)	Influenza Virus Fungal NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Hyperoside (Standard) is the analytical standard of Hyperoside. This product is intended for research and analytical applications. Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-114717

Pterophyllin 2	Fungal	Infection
Pterophyllin 2 is a fungicide against *R. stolonifer* with a MFC value of 250 μg/mL. Pterophyllin 2 also has antifungal activity against *B. cinerea* and *M. fructicola* .

HY-N12697A

Polycarpine hydrochloride	SARS-CoV Virus Protease Influenza Virus Fungal	Infection
Polycarpine hydrochloride (1a) is a broad-spectrum Mpro inhibitor (IC₅₀ = 30 nM) that can be isolated from the Polycarpa aurata and also serves as an anti-coronaviral agent. Polycarpine hydrochloride possesses antiviral and antifungal activities, with IC₅₀ values of 30.0 nM and 0.12 μM against SARS-CoV-2 Mpro and PEDV Mpro, respectively .

HY-N1300

Shizukanolide F	Fungal	Infection Cancer
Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic fungi and anti-metastasis breast cancer .

HY-N10411

Morin 3-O-β-D-glucopyranoside	Reverse Transcriptase HIV Xanthine Oxidase	Infection Cardiovascular Disease Cancer
Morin 3-O-β-D-glucopyranoside is a natural flavonoid with antifungal, anticancer and antioxidant activities. Morin 3-O-β-D-glucopyranoside inhibits reverse transcriptase, protein-tyrosine kinase and xanthine oxidase, and also shows anti-HIV, antiarteriosclerotic, and superoxide scavenging activities .

HY-146059

Antibacterial agent 99	Bacterial	Infection
Antibacterial agent 99 (compound 7b) is a potent antibacterial agent. Antibacterial agent 99 shows significant antibacterial and antifungal activity. Antibacterial agent 99 dose not show haemolytic activity .

HY-161504

SDH-IN-14	Fungal Succinate Dehydrogenase	Infection
SDH-IN-14 (Compound Z2) is an inhibitor of succinate dehydrogenase (SDH). SDH-IN-14 has *antifungal* activity (EC₅₀=2.7 μg/mL) against B.cinerea. SDH-IN-14 acts by disrupting the integrity of the cell wall and cell membrane .

HY-132191

Pradimicin A	Fungal SARS-CoV HIV	Infection
Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca ²⁺ ion .

HY-W422288

(Rac)-Ketoconazole (Rac)-Ketoconazol; (Rac)-R 41400	Fungal Cytochrome P450	Infection
(Rac)-Ketoconazole ((Rac)-R 41400) is an antifungal imidazole compound with oral activity. (Rac)-Ketoconazole interferes with ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-sterol demethylase (CYP51), a key enzyme on the fungal cell membrane, leading to membrane dysfunction and ultimately inhibition of fungal growth and reproduction. (Rac)-Ketoconazole is indicated for studies of fungal infections .

HY-156090

PK-10	Mitochondrial Metabolism Fungal	Infection
PK-10 is a synergistic antibacterial agent of Fluconazole (HY-B0101) and has strong antifungal activity against a variety of Fluconazole-resistant Candida albicans strains. PK-10 combined with Fluconazole can inhibit hyphae formation and induce the accumulation of reactive oxygen species. It further causes damage to mitochondrial membrane potential, reduces intracellular ATP content, and leads to mitochondrial dysfunction .

HY-N11706

β-Cedrene (+)-β-Cedrene	Fungal	Infection Inflammation/Immunology
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a K_i value of 1.6 μM .

HY-N11434

Anisocoumarin H	Fungal	Infection
Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL .

HY-N0540

Cynaroside 5+ Cited Publications Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside	Influenza Virus DNA/RNA Synthesis Apoptosis Parasite Bacterial Fungal	Infection Cancer
Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-148054

Antifungal agent 36	Fungal	Infection
Antifungal agent 36 is a potent *anti-fungal* agent. Antifungal agent 36 shows anti-fungal activity for Basidiomycetes .

HY-146464

Antifungal agent 30	Fungal	Infection
Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51 .

HY-155702

Antifungal agent 66	Fungal	Infection
Antifungal agent 66 (compound 10) has antifungal activity. Antifungal agent 66 has a broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia. Antifungal agent 66 has pronounced inhibitory activity against the spore of B. cinerea with an IC₅₀ value of 47.7 μg/mL .

Cat. No.	Product Name

HY-L048

Antifungal Compound Library

380 compounds

The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is challenging because there are many similarities between fungal and human cells. The most common antifungal targets include fungal RNA synthesis and cell wall and membrane components, though new antifungal targets are being investigated. Nonetheless, fungi have developed resistance mechanisms, such as overexpression of efflux pump proteins, overexpression and changes in drug targets and biofilm formation, emphasizing the importance of discovering new antifungal drugs and therapies. Due to the limited antifungal arsenal, researchers have sought to improve treatment via different approaches, such as the combination of antifungal drugs, development of new formulations for antifungal agents and modifications to the chemical structures of traditional antifungals, etc.

MCE offers a unique collection of 380 compounds with validated antifungal activities. MCE antifungal compound library is an effective tool for drug repurposing screening, combination screening and biological investigation.

HY-L002

Anti-Infection Compound Library

3,074 compounds

An infection occurs when another organism enters a person’s body and causes disease. The organisms that cause infections are very diverse and can include things like viruses, bacteria, fungi, and parasites. The immune system is an effective barrier against infectious agents.

MCE provides a unique collection of 3,074 anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities that can be used for drug screening and other research in anti-microbial area.

HY-L071

Alkaloids Library

553 compounds

Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds.

MCE designs a unique collection of 553 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

HY-L138

Heterocyclic Compound Library

5,708 compounds

Heterocyclic compounds are cyclic organic compounds which contain at least one hetero atom, the most common heteroatoms are nitrogen, oxygen ,and sulfur. Heterocycles are common in biology, featuring a wide range of structures from enzyme co-factors to amino acids and proteins. On the one hand, heterocycles are common structural units in approved drugs and in medicinal chemistry targets in the drug discovery process. In addition, heterocycles have been found as a key structure in medical chemistry and also they are frequently found in large percent of biomolecules such as vitamins, natural products ,and biologically active compounds including antifungal, anti-inflammatory, antibacterial, antioxidant, antiallergic, anti-HIV, antidiabetic, anticancer activity.

MCE offers a unique collection of 5,708 heterocyclic compounds which can be used for drug discovery for high throughput screening (HTS) and high content screening (HCS). MCE heterocyclic compound library is critical for drug discovery and development.

Cat. No.	Product Name	Type

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Fluorescent Dye

Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

Cat. No.	Product Name	Type

HY-138540

1-Dodecylimidazole 1 Publications Verification N-Dodecylimidazole	Cell Assay Reagents
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity .

HY-119445A

Sophorose monohydrate

2-O-beta-D-Glucopyranosyl-D-glucopyranose monohydrate

Carbohydrates

Sophorose (2-O-beta-D-Glucopyranosyl-D-glucopyranose) monohydrate is the disaccharide component of microbial glycolipids, which are often used as biosurfactants due to their hydrophobicity. Sophorolipids also exhibit antibacterial, antifungal, spermicidal, virucidal, and anticancer activities. In studies of Trichoderma reesei fermentation, sophorose monohydrate has been identified as a potent inducer of cellulase gene expression .

HY-D0837

Imidazole

2 Publications Verification

Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene

Cell Assay Reagents

Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG₂ and PGH₂) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL ^Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

HY-W037200

2,3,5-Tri-O-benzyl-D-ribose 2,3,5-Tri-O-benzyl-D-ribofuranose	Cell Assay Reagents
2,3,5-Tri-O-benzyl-D-ribose (Compound 1) is an effective inhibitor of Botrytis cinerea chitin synthase (CHS) with an IC₅₀ value of 1.8 μM. 2,3,5-Tri-O-benzyl-D-ribose exhibits antifungal activity and is able to inhibit the B. cinerea BD90 strain, with a MIC value of 190 μM .

HY-W008864

Lactose octaacetate β-Octaacetyllactose	Cell Assay Reagents
Lactose octaacetate shows mild to moderate antifungal activity against some fungi, but it has low or no activity against bacteria and yeast. Lactose octaacetate shows low cytotoxicity to MDBK cells, Hep-2 and MDCK cells. Lactose octaacetate has antiviral activity against PV-1 .

HY-119445

Sophorose

2-O-beta-D-Glucopyranosyl-D-glucopyranose

Carbohydrates

Sophorose is a disaccharide component of microbial glycolipids produced by yeast called sophorolipids. Due to their hydrophobic nature, sophorolipids are commonly used as biosurfactants. Sophorolipids also exhibit antibacterial, antifungal, spermicidal, virucidal, and anticancer activities. Sophorose has been identified as a potent inducer of cellulase gene expression in Trichoderma reesei fermentation studies.

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Biochemical Assay Reagents

HY-D0837R

Imidazole (Standard)

Cell Assay Reagents

Imidazole (Standard) is the analytical standard of Imidazole. This product is intended for research and analytical applications. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CLPro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

Cat. No.	Product Name	Target	Research Area

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P1975

Aureobasidin A 2 Publications Verification Basifungin	Fungal Parasite	Infection Inflammation/Immunology
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has *antifungal* and antiparasitic activity .

HY-P2322

Iturin A 1 Publications Verification	Fungal	Infection
IturinA exhibits strong *antifungal* activity against pathogenic yeast and fungi. Iturin A interacts with the cytoplasmic membrane of the target cell forming ion conducting pores.

HY-113560

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

HY-P5572

Aurein 2.5	Antibiotic Fungal Bacterial	Infection
Aurein 2.5 is an antibiotic antimicrobial peptide. Aurein 2.5 has antibacterial and antifungal activity

HY-P0068

Aminocandin HMR 3270; IP960; NXL201	Fungal	Infection
Aminocandin (HMR 3270) is water-soluble *antifungal* agent of the echinocandin class with excellent activity against Aspergillus and Candida spp. .

HY-105267

LY 121019	Fungal Antibiotic	Infection
LY 121019 is a semi-synthetic *antifungal* antibiotic with strong anticandida activity with MIC₅₀ value of 0.625 μg/mL .

HY-P3917

LfcinB (20–30)	Bacterial	Infection
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

HY-P5696

Xenopsin precursor fragment	Bacterial Parasite Fungal	Infection
Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity .

HY-P5569

SP-B peptide	Fungal	Infection
SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against strains of Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus

HY-P5639

Gageotetrin A	Peptides	Infection
Gageotetrin A is an antimicrobial peptide derived from the marine bacterium Bacillus subtilis. Gageotetrin A has antifungal activity, but none toxic to numerous human cancer cells .

HY-P5729

LL-25	Fungal	Infection
LL-25 is a fragment of LL-37 (HY-P1222) but devoid of the immunomodulatory properties of LL-37. LL-25 has antifungal and candidacidal activity .

HY-P5701

EP2	Bacterial Fungal	Infection
EP2 is an antimicrobial peptide. EP2 has antibacterial and antifungal activities. EP2 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 11.4 μg/mL .

HY-P10410

AEC5	Fungal	Infection
AEC5 is a Lipopeptoid with antifungal activity against Cryptococcus neoformans. AEC5 has no observable cytotoxicity against human lung, liver, or red blood cells at the MIC value (6.3 μg/mL) for Cryptococcus neoformans .

HY-P5703

EP5-1	Bacterial Apoptosis Fungal	Infection
EP5-1 is an antimicrobial peptide. EP5-1 has antibacterial and antifungal activities. EP5-1 also shows antitumor activity against cancer cells, and induces cell apoptosis. EP5-1 has antiviral activity against pseudorabies virus (PRV) .

HY-P5016

CRAMP-18 (mouse)	Antibiotic Bacterial Fungal	Infection Cancer
CRAMP-18 (mouse) is an antibiotic peptide without hemolytic activity. CRAMP-18 (mouse) has good inhibitory activity against Gram-negative bacteria, such as S. typhimurium and P. aeruginosa. CRAMP-18 (mouse) has the potential to study antifungal, antibacterial and antitumor .

HY-P5702

EP3	Bacterial Apoptosis Fungal	Infection
EP3 is an antimicrobial peptide. EP3 has antibacterial and antifungal activities. EP3 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 12.85 μg/mL. EP3 also shows antitumor activity against cancer cells, and induces cell apoptosis .

HY-P5071

EcAMP3	Bacterial	Infection
EcAMP3 is a hairpin-like peptide. EcAMP3 has *antifungal* and antibacterial activity. EcAMPs precursor family contains seven identical cysteine motifs: C1XXXC2(11–13)C3XXXC4 .

HY-P10596

Lasioglossin-III	Bacterial Fungal	Infection Cancer
Lasioglossin-III is an antimicrobial peptide that can be isolated from the venom of wild bees. Lasioglossin-III has high antibacterial activity against Gram-positive and Gram-negative bacteria, antifungal activity and antitumor activity. Lasioglossin-III has certain cytotoxicity against three cancer cell lines (HeLa S3, CRC SW 480 and CCRF-CEM T) with IC₅₀ values of 4, 18 and 5 μM, respectively .

HY-P2365

Histatin-8	Fungal	Infection
Histatin-8 is a part of the Histatin-3 central sequence and is known as hemagglutination-inhibiting peptide. Histatin-8 is a potent *anti-fungal* peptide. Histatin-8 shows antimicrobial activity against yeast strains. Histatin-8 can be used for oral thrush research .

HY-126810A

NP213 TFA	Fungal	Infection
NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has *anti-fungal* activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .

HY-P4370

Hepcidin-20 (human)	Bacterial Fungal	Infection
Hepcidin-20 (human) is a histidine-containing, cysteine-rich, β-sheet structured peptide. Hepcidin-20 (human) shows antifungal activity. Hepcidin-20 (human) inhibits biofilm formation and bacterial cell metabolism of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains .

HY-P1629

Temporin A	Bacterial Fungal Antibiotic	Infection
Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans) .

HY-P3906

Melittin free acid	Fungal Apoptosis Phospholipase Reactive Oxygen Species	Infection
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .

HY-P2098

Alamethicin F 50	Antibiotic Bacterial Fungal	Infection
Alamethicin F 50 is an antibiotic. Alamethicin F 50 is composed of membrane-active peptide, containing 75% Alamethicin F 50/5 and 10% Alamethicin F 50/7. Alamethicin F 50 is exhibits antifungal and antibacterial activity by disrupting the integrity of microbial cell membranes, resulting in leakage of cell contents and death of the microorganisms. Alamethicin F 50 is able to reduce the surface tension of water, which can be used as a surfactant or detergent .

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

HY-P10281

RW3	Bacterial	Infection
RW3 is a small cationic hexapeptide with amphiphilic properties. RW3 targets the plasma membrane of bacteria and works by inhibiting cell respiration and cell wall synthesis. RW3 shows high biological activity against gram-positive bacteria and does not show significant cytotoxic or hemolytic effects in previous studies. RW3 quickly kills 97% of the initial colony forming units (CFU) within 10 minutes at twice the minimum inhibitory concentration (MIC). RW3 can be used in antimicrobial and antifungal studies .

Cat. No.	Product Name	Target	Research Area

HY-P9962

Efungumab	Fungal	Infection
Efungumab is a monoclonal antibody with *antifungal* activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2446

Kakuol	Infection Asarum sieboldii Miq. Monophenols Classification of Application Fields Source classification Phenols Plants Disease Research Fields Aristolochiaceae	Fungal
Kakuol is a natural compound with antifungal activity .

HY-121615

α-Phellandrene alpha-Phellandrene	Melaleuca alternifolia Structural Classification Other Monoterpenes Terpenoids Source classification Myrtaceae Plants	Fungal
α-Phellandrene (alpha-Phellandrene) has antifungal activity. α-Phellandrene significantly inhibits the hyphal growth of P. cyclopium, destroys their cell membrane integrity and causes leakage of cellular components .

HY-N10229

Harzianum A	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Antibiotic
Harzianum A is a trichothecene that isolated from the soil-borne fungus Trichoderma harzianum. Harzianum A shows no cytotoxicity against baby hamster kidney cells, no activity against Gram-negative and Gram-positive bacteria, but modest antifungal activity at 100 μg/mL .

HY-N0452

Hyperoside 4 Publications Verification	Flavonols Structural Classification Flavonoids Classification of Application Fields Guttiferae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Hypericum monogynum L.	Influenza Virus Fungal NF-κB Apoptosis
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-123077

Norsanguinarine	Infection Alkaloids Classification of Application Fields Source classification Plants Papaver somniferum Linn. Isoquinoline Alkaloids Disease Research Fields Papaveraceae	Fungal
Norsanguinarine, an alkaloid, has antifungal activity against Alternaria brassicicola, Curvularia maculans at 1000 ppm .

HY-N3088

Phaseollidin hydrate	Structural Classification Natural Products Microorganisms Source classification	Fungal
Phaseollidin hydrate is the hydrate form of the antimicrobial phytoalexin Phaseollidin, which has lower antifungal activity than the original Phaseollidin .

HY-126872

Nikkomycin I	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Fungal
Nikkomycin I is a nucleoside peptide antibiotic found in Streptomyces tendae of the genus Streptomyces, with high antifungal, insecticidal, and acaricidal activities .

HY-N12805

α-Cadinol	Structural Classification Terpenoids Sesquiterpenes Source classification Taxodiaceae Plants Cunninghamia lanceolata var. konishii	Fungal Parasite
α-Cadinol is an antifungal agent that can inhibit the growth of Coriolus versicolor and Laetiporus sulfureus.α-Cadinol also possesses antimite activity .

HY-N3340

Macrocarpal I	Structural Classification Terpenoids Sesquiterpenes Source classification Phenols Polyphenols Myrtaceae Plants Eucalyptus globulus Labill.	Fungal
Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC₅₀ value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .

HY-N9930

Effusanin B	Structural Classification Tanacetum cinerariifolium (Treviranus) Schultz Bipontinus Terpenoids Labiatae Source classification Diterpenoids Plants	Fungal
Effusanin B (Compound 3) is a diterpenoid can be isolated from Rabdosia effusa (Maxim.) Hara. Effusanin B (Compound 3) has antifungal activity .

HY-N3488

Isodiospyrin	Quinones Structural Classification other families Diospyros virginiana L. Source classification Benzene Quinones Plants	Topoisomerase Bacterial Fungal
Isodiospyrin, a natural dimeric naphthoquinone, is a human DNA topoisomerase I (Topoisomerase) inhibitor. Isodiospyrin can prevent both DNA relaxation and kinase activities of human topoisomerase I. Isodiospyrin shows anticancer, antibacterial and antifungal activities .

HY-N0452R

Hyperoside (Standard)	Flavonols Structural Classification Flavonoids Guttiferae Source classification Phenols Polyphenols Plants Hypericum monogynum L.	Influenza Virus Fungal NF-κB Apoptosis
Hyperoside (Standard) is the analytical standard of Hyperoside. This product is intended for research and analytical applications. Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-N12697A

Polycarpine hydrochloride	Structural Classification Alkaloids Animals Other Alkaloids Source classification	SARS-CoV Virus Protease Influenza Virus Fungal
Polycarpine hydrochloride (1a) is a broad-spectrum Mpro inhibitor (IC₅₀ = 30 nM) that can be isolated from the Polycarpa aurata and also serves as an anti-coronaviral agent. Polycarpine hydrochloride possesses antiviral and antifungal activities, with IC₅₀ values of 30.0 nM and 0.12 μM against SARS-CoV-2 Mpro and PEDV Mpro, respectively .

HY-N1300

Shizukanolide F	Structural Classification Chloranthus serratus (Thunb.) Roem. et Schult. Terpenoids Sesquiterpenes Source classification Chloranthaceae Plants	Fungal
Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic fungi and anti-metastasis breast cancer .

HY-N11706

β-Cedrene (+)-β-Cedrene	Centaurea kotschyi (Boiss.) Hayek Structural Classification Natural Products Source classification Plants Compositae	Fungal
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a K_i value of 1.6 μM .

HY-N11434

Anisocoumarin H	Structural Classification Source classification Coumarins Phenylpropanoids Plants Baccharis darwinii Hook. & Arn. Compositae	Fungal
Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL .

HY-N0540

Cynaroside 5+ Cited Publications Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside	Infection Structural Classification Flavonoids Classification of Application Fields Flavones Centaurea ornata Phenols Polyphenols Umbelliferae Plants Disease Research Fields	Influenza Virus DNA/RNA Synthesis Apoptosis Parasite Bacterial Fungal
Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Cancer	Fungal IFNAR Reactive Oxygen Species
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-N0540R

Cynaroside (Standard) Luteolin 7-glucoside (Standard); Luteolin 7-O-β-D-glucoside (Standard)	Structural Classification Flavonoids Phenols	Apoptosis DNA/RNA Synthesis Parasite Bacterial Influenza Virus Fungal
Cynaroside (Standard) is the analytical standard of Cynaroside. This product is intended for research and analytical applications. Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-N0957

(±)-Pinoresinol	Structural Classification Source classification Melia azedarach L. Phenols Polyphenols Plants Meliaceae	Fungal
(±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity .

HY-N12621

Antifungal agent 91	Structural Classification Flavanonols Flavonoids Artocarpus elasticus Reinw. ex Blume Source classification Plants Moraceae	Phosphatase
Antifungal agent 91(compound 1) is a dihydroflavonol that can be isolated from the leaves of Artocarpus elasticus. Antifungal agent 91 is a PTP1B inhibitor with an IC₅₀ value of 0.17 μM. Antifungal agent 91 has antifungal activity .

HY-N10288

Eucalyptacid A	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Endogenous Metabolite
Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM .

HY-137794

Tetramethylkaempferol	Structural Classification Flavonoids Flavones Source classification Kaempferia parviflora Wall. ex Baker Plants Zingiberaceae	Fungal
Tetramethylkaempferol is an antifungal agent. Tetramethylkaempferol shows antifungal activity against Candida albicansCandida albicans with an IC₅₀ value of 17.63 µg/mL .

HY-N2502

Tetradehydropodophyllotoxin Dehydropodophyllotoxin	Infection Structural Classification Natural Products Monophenols Classification of Application Fields Source classification Phenols Dysosma versipellis (Hance) M. Cheng ex Ying Plants Berberidaceae Disease Research Fields	Fungal
Tetradehydropodophyllotoxin possesses antifungal activity .

HY-118118

Phlebiakauranol aldehyde	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Others
Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .

HY-N9378

3-Oxobetulin	Infection Structural Classification other families Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Plants Disease Research Fields Other Antibiotics	Fungal
3-Oxobetulin, an *antifungal* agent, shows antifungal activities against white rot fungus L. betulina and the brown rot fungus L. sulphureus .

HY-120753

Rimocidin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Fields	Fungal
Rimocidin, a polyene macrolide, is an *antifungal* compound. Rimocidin shows broad‐spectrum antifungal activity against multiple plant‐pathogenic fungi .

HY-19965

UK-2A Antibiotic UK 2A	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Fungal
UK-2A (Antibiotic UK 2A) is a potent antifungal antibiotic. UK-2A shows antifungal activity .

HY-N1448

Vincetoxicoside B	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Erythrina stricta Roxb. Plants Compositae Disease Research Fields	Fungal
Vincetoxicoside B shows antifungal activity .

HY-N8420

Thalifoline	Infection Alkaloids Monophenols Classification of Application Fields Source classification Phenols Plants Isoquinoline Alkaloids Disease Research Fields Menispermaceae Menispermum dauricum	Fungal
Thalifoline is an alkaloid and displays antifungal activity .

HY-N10289

Cytosporone C	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Fungal
Cytosporone C is an antifungal metabolite from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. Cytosporone C exhibits antifungal activities against Alternaria solani .

HY-N3556

Caulilexin C	Infection Alkaloids Classification of Application Fields Cruciferae Source classification Isatis tinctoria L. Plants Disease Research Fields Indole Alkaloids	Fungal
Caulilexin C is a phytoalexin from crucifers with *antifungal* activity .

HY-N10905

Rabdoserrin A	Structural Classification Terpenoids Labiatae Source classification Diterpenoids Plants Baccharis darwinii Hook. & Arn.	Fungal
Rabdoserrin A is a diterpenoid. Rabdoserrin A has antifungal activity .

HY-N8173

Valtrate hydrine B4	Infection other families Iridoids Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields	Fungal
Valtrate hydrine B4 is a natural compound with antifungal activities .

HY-N0903

Dihydrochelerythrine 12,13-Dihydrochelerythrine	Infection Alkaloids Classification of Application Fields Corydalis yanhusuo W. T. Wang Source classification Quinoline Alkaloids Macleaya cordata (Willd.) R. Br. Plants Disease Research Fields Papaveraceae	Fungal
Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity.

HY-77173

Demethoxyencecalin	Infection Natural Products Classification of Application Fields Source classification Plants Compositae Disease Research Fields Aspalathus linearis (Burm.f.) R.Dahlgren	Fungal
Demethoxyencecalin is a chromene isolated from Helianthus annuus, has *antifungal* activities .

HY-124551

Viridiol	Infection Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Disease Research Fields	Fungal Antibiotic
Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity .

HY-167831

Vermistatin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Vermistatin is a metabolite of the fungal strain Guignardia that has cytotoxic and antifungal activity .

HY-N0902

Dihydrosanguinarine 13,14-Dihydrosanguinarine	Infection Alkaloids Classification of Application Fields Source classification Quinoline Alkaloids Macleaya cordata (Willd.) R. Br. Plants Disease Research Fields Papaveraceae	Fungal
Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa; has antifungal and anticancer activity.

HY-N3457

Isosativan	Structural Classification Trifolium hybridum L. Monophenols Leguminosae Source classification Phenols Plants	Fungal
Isosativan is a natural product that can be found in Trifolium hybridum. Isosativan shows antifungal activity .

HY-126602

Kinamycin B	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Fungal
Kinamycin B is an antibiotic found in Streptomyces murayamaensis of the genus Streptomyces that exhibits antifungal activity .

HY-N12654

Irumamycin	Structural Classification Microorganisms Antibiotics Source classification	Fungal Parasite Antibiotic
Irumamycin is a natural 20-membered macrolide antibiotic. Irumamycin is active in vitro against some phytopathogenic fungi . Irumamycin also shows potent antitrypanosomal activity .

HY-N1433

Phytolaccagenin	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Phytolacca acinosa Roxb. Plants Inflammation/Immunology Disease Research Fields Phytolaccaceae	Bacterial
Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicity

HY-N0672

Pseudolaric Acid C	Infection Classification of Application Fields Pinaceae Terpenoids Source classification Diterpenoids Pseudolarix amabilis (J. Nelson) Rehder Plants Disease Research Fields	Fungal
Pseudolaric C is a diterpenoid isolated from the root bark of Pseudolarix amabilis, has antifungal activity .

HY-N7684

Picropodophyllone	Infection Classification of Application Fields Sinopodophyllum hexandrum (Royle) Ying Source classification Lignans Phenylpropanoids Plants Berberidaceae Disease Research Fields	Fungal
Picropodophyllone, an aryltetralin lignan, is isolated from leaves of Podophyllum hexandrum, and has antifungal activities .

HY-N0080

Ulopterol Peucedanol methyl ether	Infection Toddalia asiatica (L.) Lam. Natural Products Classification of Application Fields Source classification Rutaceae Plants Disease Research Fields	Bacterial Fungal
Ulopterol is a coumarin isolated from the leaves of Toddalia asiatica (L.) Lam with potent antibacterial and antifungal activities .

HY-N1198

Strictosamide	Alkaloids Structural Classification Classification of Application Fields Nauclea officinalis (Pirre ex Pitard) Merr. Source classification Rubiaceae Plants Inflammation/Immunology Disease Research Fields Indole Alkaloids	Parasite Fungal
Strictosamide has important effects on inflammation and inflammatory pain. Strictosamide possesses antiplasmodial and *antifungal* activities .

HY-N8026

Colutehydroquinone	Infection Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Isoflavones	Fungal
Colutehydroquinone is an isoflavonoid that can be found in the root bark of Colutea arborescens. Colutehydroquinone exhibits antifungal activity .

HY-N11505

Isopicropodophyllone	Structural Classification Source classification Centaurea ornata Lignans Phenylpropanoids Plants Umbelliferae	Fungal
Isopicropodophyllone, a natural compound that can be isolated from leaves of Podophyllum hexandrum, possesses antifungal activity .

HY-N3569

Cerbinal	Structural Classification Iridoids Terpenoids Source classification Rubiaceae Plants Gardenia jasminoides Ellis	Fungal
Cerbinal is a natural compound isolated from Gardenia jasminoides Ellis. Cerbinal has antifungal activity .

Cat. No.	Product Name	Chemical Structure

HY-17373S

Posaconazole-d5
Posaconazole-d₅ is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity[1].

HY-17373S1

Posaconazole-d4
Posaconazole-d₄ is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity[1].

HY-76200S

Voriconazole-d3
Voriconazole-d₃ is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].

HY-N0415S

Trigonelline-d3 chloride
Trigonelline-d₃ (chloride) is the deuterium labeled Trigonelline chloride. Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee. Trigonelline chloride has anti-HSV-1 , antibacterial, and antifungal activities.

HY-14273S

Isavuconazole-d4
Isavuconazole-d₄ is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi[1].

HY-W782079

Geraniol-d6 (Major)
Geraniol-d6 (Major) is the deuterated labeled Geraniol (Major). Geraniol is an olefin terpene with oral activity. Geraniol inhibits cell proliferation and promotes apoptosis. Geraniol has antibacterial, antifungal, antioxidant, anti-inflammatory and antitumor activities. Geraniol can be used to study diabetes .

HY-10882S

Clotrimazole-d5
Clotrimazole-d₅ is the deuterium labeled Clotrimazole. Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity[1][2].

HY-10882S1

Clotrimazole-d10
Clotrimazole-d₁₀ is deuterated labeled Clotrimazole (HY-10882). Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.

HY-77995S

2-Methoxybenzaldehyde-d3
2-Methoxybenzaldehyde-d₃ is the deuterium labeled 2-Methoxybenzaldehyde[1]. 2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity[2].

HY-B0518AS

Naftifine-d3 hydrochloride
Naftifine-d₃ (hydrochloride) is the deuterium labeled Naftifine hydrochloride. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition[1].

HY-40354AS

Tofacitinib-d3 citrate
Tofacitinib-d₃ (citrate) is deuterium labeled Tofacitinib (citrate). Tofacitinib citrate is an orally available JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively. Tofacitinib citrate has antibacterial, antifungal and antiviral activities.

HY-N7364S

(E)-β-Farnesene-d6
(E)-β-Farnesene-d₆ is deuterated labeled Nerol (HY-N7063). Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca ²⁺ and ROS. *Antifungal* activity .

HY-N7436S

Methyl propyl disulfide-d3
Methyl propyl disulfide-d₃ is deuterated labeled Nerol (HY-N7063). Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca ²⁺ and ROS. *Antifungal* activity .

HY-N0367S

Trans-Anethole-d3
Trans-Anethole-d₃ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria . α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption .

HY-W015551S

trans-2-Decenal-d2
trans-2-Decenal-d₂ is deuterated labeled Coumarin (HY-N0709). Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity .

HY-N5142S

α-Terpineol-d3
α-Terpineol-d₃ is the deuterium labeled α-Terpineol[1]. α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria[2].α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption[2].

HY-B0450S

Ciclopirox-d11
Ciclopirox-d₁₁ is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

HY-B0450S1

Ciclopirox-d11 sodium
Ciclopirox-d₁₁ (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

HY-17395S

Terbinafine-d3 hydrochloride

Terbinafine-d₃ (hydrochloride) is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-B0101S

Fluconazole-d4
Fluconazole-d₄ is the deuterium labeled Fluconazole. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL[1].

HY-17395AS

Terbinafine-d7
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-15660S

Efinaconazole-d4
Efinaconazole-d₄ is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].

HY-B0101S1

Fluconazole-13C2,15N
Fluconazole-13C2,15N (UK-49858-13C2,15N) is the ¹³C and ¹⁵N labeled isotope of Fluconazole (HY-B0101). Fluconazole (UK-49858) is a triazole *antifungal* agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

HY-10863S

Anandamide-d8

Anandamide-d8 is a deuterated labeled Anandamide . Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis .

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