2. Gene
  3. ACLY - ATP citrate lyase Gene

ACLY - ATP citrate lyase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ACL; ATPCL; CLATP

Gene ID: 47 | Gene type: protein coding

About ACLY

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:41,866,917-41,930,545 (from NCBI)

This gene has 10 transcripts (splice variants) and 282 orthologues. Ubiquitous expression in prostate (RPKM 37.3), kidney (RPKM 29.2) and 25 other tissues.

Summary

ATP Citrate Lyase is the primary Enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The Enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]

ACLY Products(5)

mRNA Protein Name
NM_198830.2 NP_942127.1 ATP-citrate synthase isoform 2
NM_001303275.1 NP_001290204.1 ATP-citrate synthase isoform 4
XM_005257395.2 XP_005257452.1 ATP-citrate synthase isoform X1
NM_001303274.1 NP_001290203.1 ATP-citrate synthase isoform 3
NM_001096.3 NP_001087.2 ATP-citrate synthase isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ATP citrate synthase activity IDA
IDA: Inferred from direct assay
1371749 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
23932781 GOA
Biological Process GO Annotation Evidence Reference Source
involved in acetyl-CoA biosynthetic process IDA
IDA: Inferred from direct assay
1371749 GOA
involved in citrate metabolic process IDA
IDA: Inferred from direct assay
1371749 GOA
involved in fatty acid biosynthetic process IDA
IDA: Inferred from direct assay
10653665 GOA
involved in lipid biosynthetic process IDA
IDA: Inferred from direct assay
23932781 GOA
involved in oxaloacetate metabolic process IDA
IDA: Inferred from direct assay
1371749 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
9116495 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ACLY Protein Structure

ATP-grasp_2

ATP-grasp_2: ATP-grasp domain (52 - 207)

CoA_binding

CoA_binding: CoA binding domain (495 - 600)

Ligase_CoA

Ligase_CoA: CoA-ligase (660 - 784)

Citrate_synt

Citrate_synt: Citrate synthase, C-terminal domain (888 - 1085)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1101 a.a.
Protein Preferred Names Protein Names

ATP-citrate synthase

ATP-citrate (pro-S-)-lyase

citrate cleavage enzyme

Recombinant ACLY Proteins

Cat. No. Product Name Accession Purity
HY-P72070 ACLY Protein, Human (His-SUMO) P53396 (K4-K265) ≥95%

Related Diseases

Diseases Alias
Diabetes Mellitus

Diabetes
Soft Palate Cancer

Malignant Tumor Of Soft Palate

Malignant Tumor Of The Soft Palate

Palate Cancer Soft Palate
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Approval
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13001 Quizartinib 99.01% Yes
HY-B0091 Adapalene 99.98% Yes
HY-B0491A Carbazochrome sodium sulfonate ≥98.0% Unkown
HY-B0393 Fudosteine ≥98.0% Unkown
HY-14277A Levocabastine hydrochloride Antagonist 99.3% Unkown
HY-14217 Quizartinib dihydrochloride 99.81% Yes
HY-B0091R Adapalene (Standard) / Unkown
HY-B0091A Adapalene sodium salt / Unkown
Clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Phase
HY-14425 NB001 Inhibitor 98.7% Phase 3
HY-15527 Emapunil 99.07% Phase 2
HY-106025 Radequinil Antagonist 99.25% Phase 2
HY-P1454 Fz7-21 Antagonist 99.59% Phase 1
HY-12010 BMS-599626 Hydrochloride Inhibitor 99.68% Phase 1
HY-144289 BMS-820132 Activator 99.75% Phase 1
HY-10251 BMS-599626 Inhibitor / Phase 1
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P99362 Ensituximab Inhibitor 95.00% Phase 2
HY-P99715 Losatuxizumab Inhibitor 95.00% Phase 2
HY-P9992 Pelgifatamab Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (392)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18657 TEPP-46 Activator 99.93% Unkown
HY-118297 Ac4ManNAz (80% α isomer) 99.74% Unkown
HY-16990 Ac-YVAD-cmk Inhibitor 98.94% Unkown
HY-100396 SQ22536 Inhibitor 99.98% Unkown
HY-16450 SB 204990 Inhibitor 99.75% Unkown
HY-P1001 Ac-DEVD-CHO Inhibitor 99.55% Unkown
HY-104032 Ac-CoA Synthase Inhibitor1 Inhibitor 99.33% Unkown
HY-W728531 Ac4ManNAz 99.37% Unkown
HY-101801 Ac-Gly-BoroPro ≥98.0% Unkown
HY-P1098 Ac2-26 Inhibitor 99.14% Unkown
HY-127111 NDI-091143 Inhibitor 99.88% Unkown
HY-124500 AC-4-130 99.93% Unkown
HY-122214 AC-73 Inducer 99.89% Unkown
HY-P1098A Ac2-26 TFA Inhibitor 99.67% Unkown
HY-111675 Ac-FLTD-CMK Inhibitor 99.53% Unkown
HY-133870 Itaconate-alkyne 98.00% Unkown
HY-141128 Ac4GalNAz 99.71% Unkown
HY-107636 DC_AC50 Inducer 99.97% Unkown
HY-110288 3FAx-Neu5Ac ≥99.0% Unkown
HY-P1003 Ac-DEVD-AMC 99.93% Unkown
HY-145765 JQAD1 98.70% Unkown
HY-149302 MC4033 99.77% Unkown
HY-15967 PS48 Activator 99.71% Unkown
HY-112942A CMP-Sialic acid sodium salt 92.51% Unkown
HY-125798 2,3-Dehydro-2-deoxy-N-acetylneuraminic acid Inhibitor ≥99.0% Unkown
HY-P1005 Ac-DEVD-AFC 98.62% Unkown
HY-100738 Ubiquitin Isopeptidase Inhibitor I, G5 Inducer ≥98.0% Unkown
HY-122051 AC1903 Inhibitor 99.80% Unkown
HY-101279 ST034307 Inhibitor 98.46% Unkown
HY-N2609 7,4'-Dihydroxyflavone Inhibitor 99.68% Unkown
HY-141866 Acid Ceramidase-IN-1 99.36% Unkown
HY-103430A SKF-83566 Antagonist 99.86% Unkown
HY-120019 Ac-YVAD-CHO Inhibitor 98.23% Unkown
HY-124004 Acetyl-6-formylpterin ≥95.0% Unkown
HY-P1393A AC 187 TFA 99.43% Unkown
HY-Y1977 100mM Pro-Ac, 20 mM Arg, pH 5.0 buffer 99.29% Unkown
HY-138159 Boc-Lys(Ac)-AMC 99.53% Unkown
HY-P1169 Ac-IETD-AFC 99.91% Unkown
HY-113338 8-Hydroxyguanine 98.37% Unkown
HY-147368 PKM2 activator 2 Activator 99.48% Unkown
HY-14350 AC-55541 Agonist 99.25% Unkown
HY-P0034A Ac-DEVD-CMK TFA Inhibitor 99.07% Unkown
HY-132197 CBP/p300-IN-12 Inhibitor 99.70% Unkown
HY-P1006 Ac-DEVD-pNA 98.12% Unkown
HY-P2617A Ac-WEHD-AFC TFA 99.01% Unkown
HY-123052 Ac-PAL-AMC ≥98.0% Unkown
HY-136744 Caspase-9 Inhibitor III Inhibitor 99.00% Unkown
HY-W014130 N-Acetyl-L-arginine 99.36% Unkown
HY-111554 AcLys-PABC-VC-Aur0101 Inhibitor 98.49% Unkown
HY-147117 NHS-SS-Ac ≥95.0% Unkown
HY-N2098 Obtusifolin Inhibitor 99.91% Unkown
HY-P1093 Ac-LEHD-AFC 98.22% Unkown
HY-P1454A Fz7-21 TFA Antagonist 99.35% Unkown
HY-148859 AA-T3A-C12 ≥98.0% Unkown
HY-123051 Ac-WLA-AMC 99.40% Unkown
HY-154818 Bovine Serum Albumin, Acetylated / Unkown
HY-79490 Ac-Exatecan Inhibitor 98.70% Unkown
HY-P2377 Ac-YVAD-AFC 99.56% Unkown
HY-32264 X-Neu5Ac sodium Inhibitor 99.98% Unkown
HY-P2091 Ac-YVAD-pNA 99.96% Unkown
HY-P3236 N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide 98.52% Unkown
HY-103195 NKY80 Inhibitor 99.69% Unkown
HY-147286 Ac-Lys-Val-Cit-PABC-MMAE 99.99% Unkown
HY-P2016 Ac-Nle-Pro-Nle-Asp-AMC 99.85% Unkown
HY-P3434A Ac-FEID-CMK TFA Inhibitor 97.06% Unkown
HY-W004066 Ac-Ala-OH ≥98.0% Unkown
HY-P1368A Stressin I TFA Agonist 98.38% Unkown
HY-108526 AC-55649 Agonist 99.70% Unkown
HY-122025 AC-262536 Agonist 99.94% Unkown
HY-160109 Ac5GalNTGc 98.39% Unkown
HY-P10149 Ac-IEPD-CHO Inhibitor 99.61% Unkown
HY-W102456 H-Phe(4-Ac)-OH 99.19% Unkown
HY-P4417A Ac-IEPD-AMC TFA / Unkown
HY-116874 SKF 83822 Agonist 98.66% Unkown
HY-123630 Allura Red AC 98.01% Unkown
HY-146356 Adenylyl cyclase type 2 agonist-1 Agonist 99.30% Unkown
HY-N9459 2-Amino-2-deoxyglucose hydrochloride ≥98.0% Unkown
HY-108312A AC-VEID-CHO TFA Inhibitor 98.7% Unkown
HY-108532 AC-261066 Agonist 98.79% Unkown
HY-116530 9-Cyclopentyladenine monomethanesulfonate Inhibitor 99.16% Unkown
HY-138586 DMT-dC(ac) Phosphoramidite Activator 99.76% Unkown
HY-148043 Schnurri-3 inhibitor-1 Inhibitor 99.07% Unkown
HY-158123 PSMA binder-1 98.33% Unkown
HY-161024 AC1Q3QWB Inhibitor 99.39% Unkown
HY-P3662 Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 Activator 99.95% Unkown
HY-W011982 Ac-DL-Trp-OH 99.49% Unkown
HY-120833 Ac-Ile-Glu-Thr-Asp-pNA 99.90% Unkown
HY-13856 (R)-PS210 Inhibitor 98.09% Unkown
HY-14351 AC-264613 Agonist 98.3% Unkown
HY-145830 AC1-IN-1 Inhibitor 99.81% Unkown
HY-148041 ATPase-IN-2 Inhibitor ≥98.0% Unkown
HY-148324 PKM2 activator 5 Activator 96.24% Unkown
HY-151852 9AzNue5Ac ≥95.0% Unkown
HY-160821A N-Acetylmannosamine 6-phosphate sodium salt ≥95.0% Unkown
HY-66007 Ac-β-Ala-OH ≥98.0% Unkown
HY-D1705 Ac-ANW-AMC 99.40% Unkown
HY-P0266B N-Acetyl-Ser-Asp-Lys-Pro acetate 98.93% Unkown
HY-P2462 Ac-Arg-Gly-Lys(Ac)-AMC 99.27% Unkown
HY-P4147 Ac-IHIHIQI-NH2 99.63% Unkown
HY-W008986 Fmoc-Lys(Ac)-OH 99.34% Unkown
HY-W096146 Propynyl-PEG1-Ac ≥95.0% Unkown
HY-13493 AC710 Inhibitor 98.56% Unkown
HY-150248 RNA splicing modulator 3 Modulator 98.58% Unkown
HY-18700 BRD73954 Inhibitor ≥98.0% Unkown
HY-21648 2'-OMe-Ac-C Phosphoramidite 99.53% Unkown
HY-45491 Dmt-2'-f-dc(ac) amidite 99.7% Unkown
HY-W114328 DMT-OMe-rC(Ac) ≥97.0% Unkown
HY-153094 BDM-2 Inhibitor 99.09% Unkown
HY-100336 AC260584 Agonist 99.60% Unkown
HY-110157 AC-186 Agonist 99.61% Unkown
HY-117851 AC-265347 Agonist 99.97% Unkown
HY-124680 AC-263093 free base 99.81% Unkown
HY-138614 5'-O-DMT-2'-O-TBDMS-Ac-rC 99.80% Unkown
HY-141464 Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH 95.03% Unkown
HY-144287 Glucokinase activator 3 Activator 98.36% Unkown
HY-144549 LXR agonist 1 Agonist 99.95% Unkown
HY-156757 MDL-811 Activator 99.68% Unkown
HY-P0280 MUC5AC motif peptide 98.79% Unkown
HY-P10142 Ac-YEVD-AMC 99.59% Unkown
HY-P1448 Ac-Leu-Arg-AMC 99.26% Unkown
HY-P4764 Ac-(d-Arg)-CEH-(d-Phe)-RWC-NH2 Agonist 99.09% Unkown
HY-P6079A Ac-IHIHIYI-NH2 TFA 99.02% Unkown
HY-W024554 AC-Asp(OtBU)-OH ≥97.0% Unkown
HY-151819 N3Ac-OPhOMe 98.21% Unkown
HY-W077279 5'-O-DMT-N4-Ac-dC 97.16% Unkown
HY-103430 SKF-83566 hydrobromide Antagonist / Unkown
HY-112942 CMP-Sialic acid / Unkown
HY-115748 Mant-GTPγS Inhibitor ≥93.0% Unkown
HY-115748A Mant-GTPγS triammonium Inhibitor / Unkown
HY-125501 Biotin-XX hydrazide 95.43% Unkown
HY-138602 5'-O-DMT-N4-Ac-2'-F-dC 99.11% Unkown
HY-138612 5'-O-DMT-3'-O-TBDMS-Ac-rC 99.18% Unkown
HY-147286A Ac-Lys-Val-Cit-PABC-MMAE formic 99.96% Unkown
HY-151516 microRNA-21-IN-2 Inhibitor ≥98.0% Unkown
HY-158118 Lys(CO-C3-p-I-Ph)-OMe 97.19% Unkown
HY-158122 Lys(CO-C3-p-I-Ph)-O-tBu 98.14% Unkown
HY-158125 PSMA binder-2 97.35% Unkown
HY-160109A Ac5GalNTGc epimer Inhibitor 98.39% Unkown
HY-D1258 AC-green 98.04% Unkown
HY-N10772 Albanin A Inhibitor 97.67% Unkown
HY-P10235 Cyclic AC253 Antagonist 99.87% Unkown
HY-P1118 Ac9-25 98.54% Unkown
HY-P1368 Stressin I Agonist / Unkown
HY-P3155 Ac-hMCH(6-16)-NH2 Agonist 99.94% Unkown
HY-P3455 Ac-SVVVRT-NH2 Modulator 98.50% Unkown
HY-P3761 Ac-Tyr-Val-Lys-Asp-aldehyde Inhibitor 99.89% Unkown
HY-P4417 Ac-IEPD-AMC / Unkown
HY-P4449 Ac-VRPR-AMC / Unkown
HY-P4840 Ac-Phe-Lys-OH 99.74% Unkown
HY-W016749 N-Acetyl-DL-aspartic acid 99.93% Unkown
HY-W145561 Neu5Acα(2-3)Galβ MP glycoside 99.43% Unkown
HY-W145646 Fmoc-L-Ser((Ac)4-β-D-Glc)-OH ≥98.0% Unkown
HY-W570884 5-Me-dC(Ac) amidite ≥97.0% Unkown
HY-154829A AC-099 hydrochloride Agonist 99.92% Unkown
HY-164054 MicroRNA modulator-2 Modulator 99.54% Unkown
HY-P10639 C5aR2 agonist P32 Agonist 99.82% Unkown
HY-P1098B Ac2-26 ammonium Degrader 97.22% Unkown
HY-P4449A Ac-VRPR-AMC TFA 99.69% Unkown
HY-W101366 AC-PHE-OME 99.87% Unkown
HY-132934 Ac32Az19 Inhibitor 99.50% Unkown
HY-163608 Ac-macropa / Unkown
HY-101863 CB-6673567 / Unkown
HY-103411 SKF83822 hydrobromide Agonist / Unkown
HY-103688 N-Ac-γ-Calicheamicin-AcBut-NHS ester / Unkown
HY-106530 Gitoformate / Unkown
HY-106560 Proglumetacin Inhibitor / Unkown
HY-113844A Ac-Gly-Lys-OMe acetate / Unkown
HY-113963 Ac-​IETD-​CHO Inhibitor / Unkown
HY-117118A AC-90179 Agonist / Unkown
HY-117616 Laurotetanine Inhibitor / Unkown
HY-117867A AVE-8063 hydrochloride / Unkown
HY-118343 AC-93253 Inhibitor / Unkown
HY-118806 AC-42 Agonist / Unkown
HY-120019A Ac-YVAD-CHO acetate Inhibitor / Unkown
HY-121738 TC AC 28 Inhibitor / Unkown
HY-128433 CK1-IN-3 Inhibitor 99.00% Unkown
HY-134567 Ac-VDVAD-CHO Inhibitor / Unkown
HY-134684 Mal-PEG3-O-Ac / Unkown
HY-135070 Ac-RLR-AMC / Unkown
HY-135070B Ac-RLR-AMC TFA / Unkown
HY-135244 Imazamethabenz-methyl / Unkown
HY-136727 Ac-LEVD-CHO Inhibitor / Unkown
HY-136728 Ac-YVAD-AOM Inhibitor / Unkown
HY-136733 Ac-DNLD-CHO Inhibitor / Unkown
HY-138583 Ac-dA Phosphoramidite / Unkown
HY-140343 Ac4GalNAl / Unkown
HY-141077 N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride / Unkown
HY-141127 Azido-PEG4-tetra-Ac-beta-D-glucose / Unkown
HY-14277 Levocabastine Antagonist / Unkown
HY-143463 AC-386 Inhibitor / Unkown
HY-147397 PKM2 activator 3 Activator / Unkown
HY-148313 PKM2 activator 4 Activator / Unkown
HY-148415 Ac-Phe-Gly-pNA / Unkown
HY-150246 RNA splicing modulator 1 Modulator / Unkown
HY-150658S DMT-2′O-TBDMS-rA(ac)-1-15N phosphoramidite / Unkown
HY-153613 Ac-PLVE-FMK Inhibitor ≥98.0% Unkown
HY-153614 Ac-VLPE-FMK Inhibitor ≥99.0% Unkown
HY-154213 5’-O-DMTr-5-MedC (Ac)-methyl phosphonamidite / Unkown
HY-154592 DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite / Unkown
HY-155115 LSD1-IN-27 Inhibitor 98.88% Unkown
HY-155229 CBP/p300-IN-21 Inhibitor / Unkown
HY-156020 Glucocerebrosidase-IN-2 Inhibitor / Unkown
HY-157171 Ac-YR-NH2 / Unkown
HY-158119A PSMA-trillium / Unkown
HY-158776 SLU-10482 Inhibitor / Unkown
HY-159095 PKR activator 5 Activator / Unkown
HY-159593 Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo / Unkown
HY-159601 CSN5-IN-1 Inhibitor / Unkown
HY-161160 Ac4ManNDAz / Unkown
HY-161519 PKM2 activator 7 Activator / Unkown
HY-162665 WIZ degrader 1 Inducer / Unkown
HY-162689 GprA Agonist / Unkown
HY-163818 WIZ degrader 2 Degrader / Unkown
HY-163819 WIZ degrader 3 Degrader / Unkown
HY-163951 (S,R,S)-AHPC-Ac / Unkown
HY-163952 (S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin / Unkown
HY-168656 Ac-Atovaquone Inhibitor / Unkown
HY-169263 AC10142A Inhibitor / Unkown
HY-18234B Leupeptin Ac-LL Inhibitor / Unkown
HY-18234C Leupeptin Ac-LL hydrochloride Inhibitor / Unkown
HY-48668 AcLys-PABC-VC-Aur0101 intermediate-1 / Unkown
HY-D1652 Ac-LEHD-AMC Chemical / Unkown
HY-D2379A closed-HMRG / Unkown
HY-E70019 alpha-2-3,6-sialidase (BiNanH2) / Unkown
HY-E70445 Chondroitinase AC II / Unkown
HY-N10628 Neu5Acα(2-6) N-Glycan / Unkown
HY-N6999 Soyasaponin Ac / Unkown
HY-N8356 13-cis-Vitamin A palmitate / Unkown
HY-N8356A 9-cis-Vitamin A palmitate / Unkown
HY-P0034 Ac-DEVD-CMK Inhibitor / Unkown
HY-P0211 [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) Antagonist / Unkown
HY-P10082 Ac-VETD-AMC / Unkown
HY-P10083 Ac-VQVD-pNA / Unkown
HY-P10084 Ac-VAD-pNA / Unkown
HY-P10144 Ac-Orn-Phe-Arg-AMC / Unkown
HY-P10146 Ac-LETD-CHO Inhibitor / Unkown
HY-P10147 Ac-LDESD-AMC Inhibitor / Unkown
HY-P10162 Ac-DMQD-AMC / Unkown
HY-P10175 Acetalin-1 Antagonist / Unkown
HY-P10177 Acetalin-3 Antagonist / Unkown
HY-P10201 Ac-GpYLPQTV-NH2 Inhibitor / Unkown
HY-P10215 Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 Inhibitor / Unkown
HY-P10231 Ac-Phe-Thiaphe-OH / Unkown
HY-P10236 Ac-WEHD-pNA / Unkown
HY-P10240 Ac-WVAD-AMC / Unkown
HY-P10241 Ac-LEHD-CHO Inhibitor / Unkown
HY-P10243 Ac-VAD-CMK Inhibitor / Unkown
HY-P10276 Ac-VAD-AFC / Unkown
HY-P10452 Ac-LEVDGWK(Dnp)-NH2 / Unkown
HY-P10656 Ac-DEVDD-TPP Inducer / Unkown
HY-P10706 Ac-ILVAGK-NH2 / Unkown
HY-P1118A Ac9-25 TFA / Unkown
HY-P1200 Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH Inhibitor / Unkown
HY-P1200A Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA Inhibitor / Unkown
HY-P1316 Ac-RYYRWK-NH2 Antagonist / Unkown
HY-P1316A Ac-RYYRWK-NH2 TFA Agonist / Unkown
HY-P1318 Ac-RYYRIK-NH2 Agonist / Unkown
HY-P1318A Ac-RYYRIK-NH2 TFA Agonist / Unkown
HY-P1393 AC 187 / Unkown
HY-P1734 Ac-MBP (1-11) / Unkown
HY-P2065 Ac-VEID-AMC / Unkown
HY-P2285 AC 253 Antagonist / Unkown
HY-P2374 Ac-DMQD-CHO Inhibitor / Unkown
HY-P2610 Ac-VEID-pNA Activator / Unkown
HY-P2615 Ac-VDVAD-AFC / Unkown
HY-P2615A Ac-VDVAD-AFC TFA / Unkown
HY-P2617 Ac-WEHD-AFC / Unkown
HY-P2620 Ac-LETD-AFC / Unkown
HY-P2717 Ac-YVAD-AMC Inhibitor / Unkown
HY-P2939 Chondroitinase AC / Unkown
HY-P2977 N-Acetylneuraminate lyase (CgNal) / Unkown
HY-P3110 Ac-DNLD-AMC / Unkown
HY-P3307 Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 / Unkown
HY-P3362 Ac-IETD-AMC / Unkown
HY-P3364 Ac-QPKK(Ac)-AMC / Unkown
HY-P3434 Ac-FEID-CMK Inhibitor / Unkown
HY-P3690 Ac-Leu-Leu-Norleucinol Inhibitor / Unkown
HY-P3940 Ac-MBP (4-14) Peptide / Unkown
HY-P4019 Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 / Unkown
HY-P4039 Ac-EEVVAC-pNA / Unkown
HY-P4040 Ac-D-DGla-LI-Cha-C Inhibitor / Unkown
HY-P4408 Ac-Arg-Gly-Lys-AMC / Unkown
HY-P4416 Ac-Gly-Ala-Lys(Ac)-AMC / Unkown
HY-P4443 Ac-GAK-AMC / Unkown
HY-P4448 Ac-Gly-Pro-AFC / Unkown
HY-P4521 Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt / Unkown
HY-P4532 Ac-Leu-Val-Lys-Aldehyde Inhibitor / Unkown
HY-P4535 Ac-Trp-Glu-His-Asp-Aldehyde Inhibitor / Unkown
HY-P4547 Ac-Trp-Glu-His-Asp-AMC / Unkown
HY-P4688 (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH / Unkown
HY-P4787 Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 / Unkown
HY-P4832 Acetyl-Tau Peptide (273-284) amide Inhibitor / Unkown
HY-P4846 Ac-Pro-Gly-Pro-OH Agonist / Unkown
HY-P5280 Ac-KQL-AMC / Unkown
HY-P5378 Ac-KQKLR-AMC / Unkown
HY-P5525 AC3-I, myristoylated Inhibitor / Unkown
HY-P5922 PTD2 Inhibitor / Unkown
HY-P5936 Ac-AAVALLPAVLLALLAP-DEVD-CHO Inhibitor / Unkown
HY-P5938 Ac-AAVALLPAVLLALLAP-YVAD-CHO Inhibitor / Unkown
HY-P5955 Ac-AAVALLPAVLLALLAP-LEVD-CHO Inhibitor / Unkown
HY-P5956 Ac-AAVALLPAVLLALLAP-LEHD-CHO Inhibitor / Unkown
HY-P5983 Ac-VEID-AFC / Unkown
HY-P6079 Ac-IHIHIYI-NH2 / Unkown
HY-R01635 hsa-miR-548ac mimic / Unkown
HY-R01635A hsa-miR-548ac agomir / Unkown
HY-RI01635 hsa-miR-548ac inhibitor / Unkown
HY-RI01635A hsa-miR-548ac antagomir / Unkown
HY-RS00166 ACLY Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00167 Acly Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00168 Acly Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS05088 FRA10AC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS05955 H2AC18 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08844 MUC5AC Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W011254 Ac-VAD-CHO Inhibitor / Unkown
HY-W012713 Ac-D-Ala-OH ≥98.0% Unkown
HY-W013322 Ac-Tyr-OEt.H2O ≥98.0% Unkown
HY-W014130A N-Acetyl-L-arginine dihydrate / Unkown
HY-W015241 Ac-D-Glu-OH / Unkown
HY-W016584 4,5-Dichlorocatechol Inhibitor / Unkown
HY-W040802 AC-94149 / Unkown
HY-W042357S Ac-rC Phosphoramidite-15N / Unkown
HY-W042357S1 Ac-rC Phosphoramidite-15N2 / Unkown
HY-W042357S2 Ac-rC Phosphoramidite-15N3 / Unkown
HY-W042357S4 Ac-rC Phosphoramidite-13C9 / Unkown
HY-W042357S6 Ac-rC Phosphoramidite-13C9,15N3 / Unkown
HY-W044285 Fmoc-D-4-Aph(cBm)-OH / Unkown
HY-W048674 Fmoc-Ser(Ac)-OH 97.40% Unkown
HY-W101384 Ac-D-2-Nal-OH / Unkown
HY-W114327 N4-Acetyl-2'-O-methylcytidine / Unkown
HY-W145531 Neu5GcAc[1Me,478Ac,9N3]-β-SPh / Unkown
HY-W145540 Galβ(1-3)[Neu5Acα(2-6)]GalNAc-α-pNP / Unkown
HY-W145548 GlcNPhth[36Bn,4Ac]-β-MP / Unkown
HY-W145609 Neu5Troc[1Me,4789Ac]α(2-3)Gal[26Bn]-β-MP / Unkown
HY-W145622 Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP / Unkown
HY-W214058 Ac-2-Nal-OH / Unkown
HY-W393498 Phenyl 2,4,6-tri-O-acetyl-3-O-allyl-β-D-thiogalactopyranoside / Unkown
HY-W415798 Ac4GalNAlk / Unkown
HY-W560922 Piperazine-Ac-OMe / Unkown
HY-W560961 3',5'-TIPS-N-Ac-Adenosine / Unkown
HY-W713878 Ac-VDVAD-pNA / Unkown
HY-W854187 2'-Ome-Ac-G Phosporamidite / Unkown
HY-10658 AC-7954 / Unkown
HY-108312 AC-VEID-CHO Inhibitor / Unkown
HY-110209 AC4 Antagonist / Unkown
HY-113844 Ac-Gly-Lys-OMe / Unkown
HY-118464 AC915 / Unkown
HY-118806A AC-42 hydrochloride Agonist / Unkown
HY-120278 4-Ethoxyquinazoline / Unkown
HY-121248 Hydramethylnon Inhibitor / Unkown
HY-121699 Kibdelone B / Unkown
HY-129027 Ac-Leu-Gly-Lys(Ac)MCA / Unkown
HY-129648 AC-7954 free base / Unkown
HY-13493A AC710 Mesylate Inhibitor / Unkown
HY-135020 AC-24,055 / Unkown
HY-136666 Antibiotic AC4437 / Unkown
HY-138165 Ac-Phe-NH2 / Unkown
HY-154036 5′-DMTr-dC (Ac)-Methylphosphonamidite / Unkown
HY-154829 AC-099 Agonist / Unkown
HY-156287 GCase modulator-1 Modulator ≥97.0% Unkown
HY-157232 AC Antibody purification resin 2 / Unkown
HY-157233 AC Antibody purification resin 1 / Unkown
HY-157234 AC mAb-X purification resin / Unkown
HY-157235 AC Antibody affinity resin / Unkown
HY-158783 SACLAC / Unkown
HY-158792 GK241 / Unkown
HY-16020 AC-430 hydrobromide Inhibitor / Unkown
HY-161021 AC2 selective-IN-1 / Unkown
HY-161913 AC-4-248 Inhibitor / Unkown
HY-162159 Ac-Cys-NHMe / Unkown
HY-163106 W000113414_I13 Agonist / Unkown
HY-163820 WIZ degrader 4 Degrader / Unkown
HY-164053 MicroRNA modulator-1 Modulator 99.58% Unkown
HY-164248 Ac-rG / Unkown
HY-164249 DMT-rG(Ac) / Unkown
HY-164253 TBS-rG(Ac) / Unkown
HY-19647 Ritipenem acoxil Inhibitor / Unkown
HY-20560 (Ac)Phe-Lys(Alloc)-PABC-PNP / Unkown
HY-N12336 Gnetuhainin I / Unkown
HY-N12894 (Z,E)-7,11-Hexadecadienyl acetate / Unkown
HY-N12920 (Z)-3-Dodecenyl acetate / Unkown
HY-P10336 Serpinin Agonist / Unkown
HY-P10639A C5aR2 agonist P32 acetate Agonist / Unkown
HY-P10657 Ac-DEMEEC-OH Inhibitor / Unkown
HY-P10666 Ac-VDQQD-pNA / Unkown
HY-P10668 Ac-EVKKQR-pNA Inhibitor / Unkown
HY-P3234 Ac-ESMD-CHO Inhibitor / Unkown
HY-W042357 Ac-rC Phosphoramidite 98.87% Unkown
HY-W129441 N-Acetyl-4-S-cysteaminylphenol / Unkown
HY-W130878 4-Octylphenol Activator / Unkown
HY-W131753 2'-F-Ac-C / Unkown
HY-W780787 (E,Z)-3,13-Octadecadienyl acetate / Unkown
HY-W783407 Ac-rG Phosporamidite / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ACLY VGNC VGNC:59513
Canis familiaris ACLY VGNC VGNC:37511
Macaca mulatta ACLY VGNC VGNC:99112
Rattus norvegicus ACLY RGD RGD:2018
Bos taurus ACLY VGNC VGNC:25543
Mus musculus ACLY MGD MGI:103251
Others ACLY NCBI