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Hyoscine-d<sub>3</sub> hydrobromide

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By Research Areas:	Cancer (194) Cardiovascular Disease (32) Endocrinology (23) Infection (84) Inflammation/Immunology (66) Metabolic Disease (109) Neurological Disease (107)
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Oligonucleotides:	Pre-designed siRNA Sets (1) Polymers (1) siRNAs (1)

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Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010892

*Scopolamine hydrobromide* trihydrate** 10+ Cited Publications Hyoscine hydrobromide trihydrate	mAChR	Neurological Disease
Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness .

HY-N0898S

Catechin-13C3 (+)-Catechin-¹³C<sub>3sub>; Cianidanol-¹³C<sub>3sub>; Catechuic acid-¹³C<sub>3sub>	COX Apoptosis Influenza Virus Endogenous Metabolite	Cancer
Catechin- ¹³C₃ is the ¹³C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

HY-D0184S2

2'-Deoxycytidine-15N3 Deoxycytidine-¹⁵N<sub>3sub>; Cytosine deoxyriboside-¹⁵N<sub>3sub>; Deoxyribose cytidine-¹⁵N<sub>3sub>	Endogenous Metabolite	Others
2'-Deoxycytidine- ¹⁵N₃ is the ¹⁵N labeled 2'-Deoxycytidine[1]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu)[2].

HY-40354S

Tofacitinib-13C3 Tasocitinib-¹³C<sub>3sub>; CP-690550-¹³C<sub>3sub>	JAK Apoptosis	Inflammation/Immunology Cancer
Tofacitinib- ¹³C₃ is the ¹³C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-W010892R

*Scopolamine (hydrobromide* trihydrate) (Standard)**	mAChR	Neurological Disease
Scopolamine (hydrobromide trihydrate) (Standard) is the analytical standard of Scopolamine (hydrobromide trihydrate). This product is intended for research and analytical applications. Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness .

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-A0253S

Cefacetrile-13C3 Cephacetrile-¹³C<sub>3sub>; Cephacetril-¹³C<sub>3sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Others
Cefacetrile- ¹³C₃ is the ¹³C₃ labeled Cefacetrile.

HY-B0139AS

Flucytosine-15N3 hydrochloride 5-Fluorocytosine-¹⁵N<sub>3sub> hydrochloride; NSC 103805-¹⁵N<sub>3sub> hydrochloride; Ro 2-9915-¹⁵N<sub>3sub> hydrochloride	Isotope-Labeled Compounds	Others
Flucytosine- ¹⁵N₃ hydrochloride is ¹⁵N labeled Flucytosine.

HY-B0234S

Estrone-13C3 E1-¹³C<sub>3sub>; Oestrone-¹³C<sub>3sub>	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Estrone- ¹³C₃ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B1331S1

Cyromazine-13C3 Cyromazin-¹³C<sub>3sub>; CGA-72662-¹³C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Cyromazine- ¹³C₃ is the ¹³C₃ labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium PQQ-¹³C<sub>3sub> sodium; Methoxatin-¹³C<sub>3sub> sodium	Endogenous Metabolite	Inflammation/Immunology
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-B1804S

Tricaprilin-13C3 Trioctanoin-¹³C<sub>3sub>; Glyceryl trioctanoate-¹³C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Tricaprilin-13C3 is a deuterated labeled Tricaprilin . Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite ^[3].

HY-W653853

Ritonavir-13C3 ABT 538-¹³C<sub>3sub>; RTV-¹³C<sub>3sub>	Isotope-Labeled Compounds Apoptosis SARS-CoV HIV Protease HIV	Cancer
Ritonavir- ¹³C₃ is ¹³C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.61 μM .

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Parasite	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-B0389S18

D-Glucose-13C3-1 Glucose-¹³C<sub>3sub>-1; D-(+)-Glucose-¹³C<sub>3sub>-1; Dextrose-¹³C<sub>3sub>-1	Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C₃-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S9

D-Glucose-13C3-2 Glucose-¹³C<sub>3sub>-2; D-(+)-Glucose-¹³C<sub>3sub>-2; Dextrose-¹³C<sub>3sub>-2	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C₃-2 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-W654126

Cytarabine-13C3 Cytosine β-D-arabinofuranoside--¹³C<sub>3sub>; Cytosine Arabinoside--¹³C<sub>3sub>; Ara-C-¹³C<sub>3sub>	Isotope-Labeled Compounds	Others
Cytarabine- ¹³C₃ (Cytosine β-D-arabinofuranoside- ¹³C₃) is ¹³C labeled Cytarabine .

HY-N0650S

L-Serine-13C3 (-)-Serine-¹³C<sub>3sub>; (S)-Serine-¹³C<sub>3sub>	Endogenous Metabolite	Cancer
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-B0495S4

Lamotrigine-13C3 LTG-¹³C<sub>3sub>; BW430C-¹³C<sub>3sub>	Sodium Channel Autophagy	Neurological Disease
Lamotrigine- ¹³C₃ is the ¹³C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

HY-D0184S3

2'-Deoxycytidine-13C9,15N3 Deoxycytidine-¹³C<sub>9sub>,¹⁵N<sub>3sub>; Cytosine deoxyriboside-¹³C<sub>9sub>,¹⁵N<sub>3sub>; Deoxyribose cytidine-¹³C<sub>9sub>,¹⁵N<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxycytidine- ¹³C₉, ¹⁵N₃ (Deoxycytidine- ¹³C₉, ¹⁵N₃; Cytosine deoxyriboside- ¹³C₉, ¹⁵N₃; Deoxyribose cytidine- ¹³C₉, ¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-N0680S3

Thiamine-13C3 hydrochloride Thiamine chloride-¹³C<sub>3sub> hydrochloride; Vitamin B1-¹³C<sub>3sub> hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis HBV	Neurological Disease
Thiamine- ¹³C₃ (hydrochloride) is the ¹³C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-14605S

Rasagiline-13C3 mesylate (R)-AGN1135-¹³C<sub>3sub> mesylate; TVP1012-¹³C<sub>3sub> mesylate	Isotope-Labeled Compounds	Others
Rasagiline- ¹³C₃ ((R)-AGN1135- ¹³C₃; TVP1012- ¹³C₃) mesylateis the deuterium labeledRasagiline (mesylate)(HY-14605) . Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively .

HY-W700491

AalphaC-15N3 2-Amino-α-carboline-¹⁵N<sub>3sub>; AαC-¹⁵N<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
AalphaC- ¹⁵N₃ (2-Amino-α-carboline- ¹⁵N₃) is ¹⁵N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .

HY-118406B

Ethybenztropine hydrobromide Ponalid hydrobromide; UK 738 hydrobromide	mAChR	Neurological Disease
Ethybenztropine hydrobromide (Ponalid hydrobromide) is an anticholinergic drug with antiparkinsonian activity. Ethybenztropine hydrobromide may also act as a dopamine reuptake inhibitor. Ethybenztropine hydrobromide is commonly used to suppress Parkinson's disease .

HY-Y0921S3

(±)-1,2-Propanediol-13C3 1,2-(RS)-Propanediol-¹³C<sub>3sub>; 1,2-Propylene glycol-¹³C<sub>3sub>; Propylene glycol-¹³C<sub>3sub>	Endogenous Metabolite Isotope-Labeled Compounds	Neurological Disease
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-14605BS

Rasagiline-13C3 mesylate racemic AGN1135-¹³C<sub>3sub>; TVP1012-¹³C<sub>3sub> racemic	Isotope-Labeled Compounds Monoamine Oxidase	Neurological Disease
Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0891S1

17α-Hydroxyprogesterone-13C3 17-Hydroxyprogesterone-¹³C<sub>3sub>; 17-OHP-¹³C<sub>3sub>	Progesterone Receptor Endogenous Metabolite	Others
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-N0086S3

N6-Methyladenosine-13C3 6-Methyladenosine-¹³C<sub>3sub>; N-Methyladenosine-¹³C<sub>3sub>	Isotope-Labeled Compounds Influenza Virus Endogenous Metabolite	Infection
N6-Methyladenosine- ¹³C₃ (6-Methyladenosine- ¹³C₃) is ¹³C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities ^[3].

HY-W777148

Anagrelide-13C3 BL 4162A-¹³C<sub>3sub>; BMY 26538-01-¹³C<sub>3sub>	Isotope-Labeled Compounds	Others
Anagrelide- ¹³C₃ (BL 4162A- ¹³C₃) is ¹³C labeled Anagrelide .

HY-113008AS

cis-Urocanic acid-13C3 (Z)-Urocanic acid-¹³C<sub>3sub>; cis-UCA-¹³C<sub>3sub>	Isotope-Labeled Compounds 5-HT Receptor	Inflammation/Immunology
cis-Urocanic acid- ¹³C₃ is the ¹³C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].

HY-B1342S3

Vitamin A-13C3 Vitamin A1-¹³C<sub>3sub>; all-trans-Retinol-¹³C<sub>3sub>	Isotope-Labeled Compounds	Others
Vitamin A- ¹³C₃ (Vitamin A1- ¹³C₃; all-trans-Retinol- ¹³C₃) is a ¹³C-labeled Vitamin A/Vitamin A (HY-B1342). Vitamin A is an endogenous metabolite.

HY-N0584A

Anisodamine hydrobromide 6-Hydroxyhyoscyamine hydrobromide	mAChR	Inflammation/Immunology Cancer
Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties .

HY-Y0219S

1,2,4-Triazole-13C2,15N3 s-Triazole¹³C<sub>2sub>,¹⁵N<sub>3sub>; Pyrrodiazole¹³C<sub>2sub>,¹⁵N<sub>3sub>	Isotope-Labeled Compounds	Others
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-106688A

Alinidine hydrobromide St-567 hydrobromide	Others	Cardiovascular Disease
Alinidine (St-567) hydrobromide is a specific bradycardic agent. Alinidine hydrobromide reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine hydrobromide shows antiischemic and antiarrhythmic effects .

HY-N0610AS2

Cinnamic acid-13C3 3-Phenylacrylic acid-¹³C<sub>3sub>; β-Phenylacrylic acid-¹³C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Cinnamic acid- ¹³C₃ (3-Phenylacrylic acid- ¹³C₃) is the ¹³C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC₅₀s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells .

HY-18569S4

3-Indoleacetic acid-13C6 Indole-3-acetic acid-¹³C<sub>6sub>; 3-IAA-¹³C<sub>6sub>	Endogenous Metabolite Molecular Glues	Others
3-Indoleacetic acid- ¹³C₆ is the ¹³C labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-19867A

Burixafor hydrobromide 1 Publications Verification TG-0054 hydrobromide	CXCR	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well anti-angiogenic drug that is of potential value in treating choroid neovascularization . Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction .

HY-A0009R

*Galanthamine hydrobromide* (Standard)** Galantamine hydrobromide (Standard)	nAChR Cholinesterase (ChE)	Neurological Disease
Galanthamine (hydrobromide) (Standard) is the analytical standard of Galanthamine (hydrobromide). This product is intended for research and analytical applications. Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC₅₀ of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α₃β₄, α₄β₂, α₆β₄ nicotinic receptors ( nAChRs). Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD) ^[3].

HY-16702A

Pifithrin-β hydrobromide 10+ Cited Publications PFT β hydrobromide; Cyclic Pifithrin-α hydrobromide	MDM-2/p53 Ferroptosis	Cancer
Pifithrin-β hydrobromide (PFT β hydrobromide) is a potent p53 inhibitor with an IC₅₀ of 23 μM.

HY-A0009

Galanthamine hydrobromide 10+ Cited Publications Galantamine hydrobromide	Cholinesterase (ChE) nAChR	Neurological Disease
Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC₅₀ of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α₃β₄, α₄β₂, α₆β₄ nicotinic receptors ( nAChRs). Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD) ^[3].

HY-14452A

Fatostatin hydrobromide 25+ Cited Publications 125B11 hydrobromide	Fatty Acid Synthase (FASN)	Cancer
Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin hydrobromide decreases the transcription of lipogenic genes in cells. Fatostatin hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice .

HY-125818S6

Cytidine-5'-triphosphate-15N3 dilithium Cytidine triphosphate-¹⁵N<sub>3sub> dilithium; 5'-CTP-¹⁵N<sub>3sub> dilithium	Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite	Infection Cancer
Cytidine-5'-triphosphate- ¹⁵N₃ (Cytidine triphosphate- ¹⁵N₃ dilithium; 5'-CTP- ¹⁵N₃) dilithium is ¹⁵N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-101400S3

Deoxycytidine triphosphate-15N3 dilithium dCTP-¹⁵N<sub>3sub> dilithium; 2′-Deoxycytidine-5′-triphosphate-¹⁵N<sub>3sub> dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate- ¹⁵N₃ (dCTP- ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃) dilithium is ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-15484

Pifithrin-α hydrobromide Maximum Cited Publications 65 Publications Verification Pifithrin hydrobromide; PFTα hydrobromide	MDM-2/p53 Aryl Hydrocarbon Receptor Ferroptosis Apoptosis	Cancer
Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist.

HY-B1081A

Oxidopamine hydrobromide 20+ Cited Publications 6-Hydroxydopamine hydrobromide; 6-OHDA hydrobromide	Dopamine Receptor Autophagy Mitophagy COX PGE synthase Interleukin Related p38 MAPK Apoptosis Caspase	Neurological Disease Cancer
Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrobromide is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrobromide promotes COX-2 activation, leading to PGE₂ synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrobromide can be used for the research of Parkinson’s disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome ^[3] .

HY-N0471B

L-Hyoscyamine hydrobromide Hyoscyamine hydrobromide	Others	Neurological Disease
L-Hyoscyamine (Hyoscyamine) hydrobromide is an anticholinergic agent that may potentially affect breastfeeding and milk production. L-Hyoscyamine hydrobromide is not likely to interfere with breastfeeding when used in single doses. L-Hyoscyamine hydrobromide should be monitored for signs of decreased lactation during long-term use.

HY-118700A

2-Iminobiotin hydrobromide Guanidinobiotin hydrobromide	NO Synthase	Neurological Disease
2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with K_is of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively . 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage .

HY-139427S

3-Methylglutaconic acid-13C3 β-Methylglutaconic acid-¹³C<sub>3sub>	Isotope-Labeled Compounds	Others
3-Methylglutaconic acid- ¹³C₃ is the ¹³C labeled 3-Methylglutaconic acid[1].

HY-B1098A

Hydroxyamphetamine hydrobromide 4-Hydroxyamphetamine hydrobromide	Others	Neurological Disease
Hydroxyamphetamine (4-Hydroxyamphetamine) hydrobromide is a sympathomimetic agent, stimulates the sympathetic nervous system. Hydroxyamphetamine hydrobromide can be used in eye drops to dilate the pupil .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010892

*Scopolamine hydrobromide* trihydrate** 10+ Cited Publications Hyoscine hydrobromide trihydrate	Alkaloids Structural Classification Other Alkaloids Source classification Datura metel L. Solanaceae Plants	mAChR
Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness .

HY-N0584A

Anisodamine hydrobromide 6-Hydroxyhyoscyamine hydrobromide	Alkaloids Structural Classification Pyrrole Alkaloids Classification of Application Fields Anisodus tanguticus (Maxinowicz) Pascher Source classification Solanaceae Plants Inflammation/Immunology Disease Research Fields	mAChR
Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties .

HY-A0009

Galanthamine hydrobromide Maximum Cited Publications 14 Publications Verification Galantamine hydrobromide	Structural Classification Alkaloids Other Alkaloids Plants Amaryllidaceae	Cholinesterase (ChE) nAChR
Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC₅₀ of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α₃β₄, α₄β₂, α₆β₄ nicotinic receptors ( nAChRs). Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD) ^[3].

HY-N2037C

(S)-Higenamine hydrobromide (S)-Norcoclaurine hydrobromide	Structural Classification Alkaloids Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Endogenous metabolite Isoquinoline Alkaloids Disease Research Fields	Endogenous Metabolite
(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-128975

m-Tyramine hydrobromide	Structural Classification Alkaloids Monophenols Neurological Disease Classification of Application Fields Other Alkaloids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
m-Tyramine hydrobromide is an endogenous trace amine neuromodulator. m-Tyramine hydrobromide has effects on the adrenergic and dopaminergic receptor ^{[1, 2]}.

HY-W010892R

*Scopolamine (hydrobromide* trihydrate) (Standard)**	Alkaloids Structural Classification Other Alkaloids Source classification Datura metel L. Solanaceae Plants	mAChR
Scopolamine (hydrobromide trihydrate) (Standard) is the analytical standard of Scopolamine (hydrobromide trihydrate). This product is intended for research and analytical applications. Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness .

HY-A0009R

*Galanthamine hydrobromide* (Standard)** Galantamine hydrobromide (Standard)	Structural Classification Alkaloids Other Alkaloids Source classification Plants Amaryllidaceae	nAChR Cholinesterase (ChE)
Galanthamine (hydrobromide) (Standard) is the analytical standard of Galanthamine (hydrobromide). This product is intended for research and analytical applications. Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC₅₀ of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α₃β₄, α₄β₂, α₆β₄ nicotinic receptors ( nAChRs). Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD) ^[3].

HY-N0584AR

*Anisodamine hydrobromide* (Standard)**	Alkaloids Structural Classification Pyrrole Alkaloids Anisodus tanguticus (Maxinowicz) Pascher Source classification Solanaceae Plants	mAChR
Anisodamine (hydrobromide) (Standard) is the analytical standard of Anisodamine (hydrobromide). This product is intended for research and analytical applications. Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties .

HY-B0489R

*Arecoline (hydrobromide) (Standard)*	Alkaloids Structural Classification Areca catechu L. Other Alkaloids Source classification Palmae Plants	mAChR nAChR
Arecoline (hydrobromide) (Standard) is the analytical standard of Arecoline (hydrobromide). This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress ^[3] .

HY-N6619

Lycoramine hydrobromide	Alkaloids other families Source classification Plants	Cholinesterase (ChE)
Lycoramine hydrobromide, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine hydrobromide is a potent acetylcholinesterase (AChE) inhibitor .

HY-N6621A

Hippeastrine hydrobromide	Structural Classification Natural Products Source classification Plants Amaryllidaceae Pancratium canariense Ker Gawl.	Topoisomerase
Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC₅₀ of 7.25?μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-129905A

L-Leucyl-L-Leucine methyl ester hydrobromide 5+ Cited Publications LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress ^[3].

HY-B0489

Arecoline hydrobromide 2 Publications Verification methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide	Structural Classification Neurological Disease Classification of Application Fields Areca catechu L. Source classification Metabolic Disease Plants Infection Alkaloids Other Alkaloids Palmae Inflammation/Immunology Disease Research Fields	mAChR nAChR
Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress ^[3] .

HY-N8580

Hydrocotarnine hydrobromide	Structural Classification Alkaloids Vaccinium macrocarpon Aiton Source classification Ericaceae Plants Isoquinoline Alkaloids	Others
Hydrocotarnine (hydrobromide) is a Alkaloids product that can be isolated from From Vaccinium macrocarpon .

HY-107670

Dihydro-β-erythroidine hydrobromide 1 Publications Verification DHβE hydrobromide	Alkaloids Piperidine Alkaloids Leguminosae Source classification Plants Erythrina	nAChR
Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC₅₀s of 0.19 and 0.37 μM, respectively. Antidepressant-like activities ^[3].

HY-101414A

L-DABA hydrobromide L-2,4-Diaminobutyric acid hydrobromide	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite GABA Receptor
L-DABA (L-2,4-Diaminobutyric acid) hydrobromide is a week GABA transaminase inhibitor with an IC₅₀ of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N1584AR

*Halofuginone hydrobromide* (Standard)**	Alkaloids Piperidine Alkaloids Structural Classification Dichroa febrifuga Lour Source classification Saxifragaceae Plants	DNA/RNA Synthesis TGF-beta/Smad Parasite Sodium Channel Calcium Channel
Halofuginone (hydrobromide) (Standard) is the analytical standard of Halofuginone (hydrobromide). This product is intended for research and analytical applications. Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM . Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity ^[3] . Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3] .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-N1584A

Halofuginone hydrobromide 10+ Cited Publications RU-19110 hydrobromide	Infection Cardiovascular Disease Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Dichroa febrifuga Lour Source classification Saxifragaceae Plants Inflammation/Immunology Disease Research Fields	DNA/RNA Synthesis TGF-beta/Smad Parasite Sodium Channel Calcium Channel
Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM . Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity ^[3] . Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

Cat. No.	Product Name	Chemical Structure

HY-N0898S

Catechin-13C3
Catechin- ¹³C₃ is the ¹³C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

HY-D0184S2

2'-Deoxycytidine-15N3
2'-Deoxycytidine- ¹⁵N₃ is the ¹⁵N labeled 2'-Deoxycytidine[1]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu)[2].

HY-40354S

Tofacitinib-13C3
Tofacitinib- ¹³C₃ is the ¹³C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

HY-A0253S

Cefacetrile-13C3
Cefacetrile- ¹³C₃ is the ¹³C₃ labeled Cefacetrile.

HY-B0139AS

Flucytosine-15N3 hydrochloride
Flucytosine- ¹⁵N₃ hydrochloride is ¹⁵N labeled Flucytosine.

HY-B0234S

Estrone-13C3
Estrone- ¹³C₃ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B1331S1

Cyromazine-13C3
Cyromazine- ¹³C₃ is the ¹³C₃ labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-B1804S

Tricaprilin-13C3
Tricaprilin-13C3 is a deuterated labeled Tricaprilin . Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite ^[3].

HY-W653853

Ritonavir-13C3
Ritonavir- ¹³C₃ is ¹³C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.61 μM .

HY-B0389S18

D-Glucose-13C3-1
D-Glucose- ¹³C₃-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S9

D-Glucose-13C3-2
D-Glucose- ¹³C₃-2 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-W654126

Cytarabine-13C3
Cytarabine- ¹³C₃ (Cytosine β-D-arabinofuranoside- ¹³C₃) is ¹³C labeled Cytarabine .

HY-N0650S

L-Serine-13C3
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-B0495S4

Lamotrigine-13C3
Lamotrigine- ¹³C₃ is the ¹³C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

HY-D0184S3

2'-Deoxycytidine-13C9,15N3
2'-Deoxycytidine- ¹³C₉, ¹⁵N₃ (Deoxycytidine- ¹³C₉, ¹⁵N₃; Cytosine deoxyriboside- ¹³C₉, ¹⁵N₃; Deoxyribose cytidine- ¹³C₉, ¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-N0680S3

Thiamine-13C3 hydrochloride
Thiamine- ¹³C₃ (hydrochloride) is the ¹³C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-14605S

Rasagiline-13C3 mesylate
Rasagiline- ¹³C₃ ((R)-AGN1135- ¹³C₃; TVP1012- ¹³C₃) mesylateis the deuterium labeledRasagiline (mesylate)(HY-14605) . Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively .

HY-W700491

AalphaC-15N3

AalphaC- ¹⁵N₃ (2-Amino-α-carboline- ¹⁵N₃) is ¹⁵N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .

HY-Y0921S3

(±)-1,2-Propanediol-13C3
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-14605BS

Rasagiline-13C3 mesylate racemic

Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0891S1

17α-Hydroxyprogesterone-13C3
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-N0086S3

N6-Methyladenosine-13C3
N6-Methyladenosine- ¹³C₃ (6-Methyladenosine- ¹³C₃) is ¹³C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities ^[3].

HY-W777148

Anagrelide-13C3
Anagrelide- ¹³C₃ (BL 4162A- ¹³C₃) is ¹³C labeled Anagrelide .

HY-113008AS

cis-Urocanic acid-13C3
cis-Urocanic acid- ¹³C₃ is the ¹³C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].

HY-B1342S3

Vitamin A-13C3
Vitamin A- ¹³C₃ (Vitamin A1- ¹³C₃; all-trans-Retinol- ¹³C₃) is a ¹³C-labeled Vitamin A/Vitamin A (HY-B1342). Vitamin A is an endogenous metabolite.

HY-Y0219S

1,2,4-Triazole-13C2,15N3
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-N0610AS2

Cinnamic acid-13C3
Cinnamic acid- ¹³C₃ (3-Phenylacrylic acid- ¹³C₃) is the ¹³C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC₅₀s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells .

HY-18569S4

3-Indoleacetic acid-13C6
3-Indoleacetic acid- ¹³C₆ is the ¹³C labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-125818S6

Cytidine-5'-triphosphate-15N3 dilithium

Cytidine-5'-triphosphate- ¹⁵N₃ (Cytidine triphosphate- ¹⁵N₃ dilithium; 5'-CTP- ¹⁵N₃) dilithium is ¹⁵N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-101400S3

Deoxycytidine triphosphate-15N3 dilithium
Deoxycytidine triphosphate- ¹⁵N₃ (dCTP- ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃) dilithium is ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-139427S

3-Methylglutaconic acid-13C3
3-Methylglutaconic acid- ¹³C₃ is the ¹³C labeled 3-Methylglutaconic acid[1].

HY-B0412S3

Estriol-13C3
Estriol- ¹³C₃ is the ¹³C-labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

HY-B1659S5

Glycerol-13C3
Glycerol- ¹³C₃ is the ¹³C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].

HY-N0136S1

(±)-Taxifolin-13C3

(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-B0111RS

Drospirenone-13C3
Drospirenone- ¹³C₃ is ¹³C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone .

HY-B0158S5

Cytidine-13C9,15N3
Cytidine- ¹³C₉, ¹⁵N₃ is the ¹³C and ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-W009162S5

Cytidine 5′-monophosphate-13C9,15N3 dilithium

Cytidine 5′-monophosphate- ¹³C₉, ¹⁵N₃ (5'-Cytidylic acid- ¹³C₉, ¹⁵N₃ dilithium; 5'-CMP- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-101400S2

Deoxycytidine triphosphate-13C9,15N3 dilithium

Deoxycytidine triphosphate- ¹³C₉, ¹⁵N₃ (dCTP- ¹³C₉, ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-B0158S6

Cytidine-15N3
Cytidine- ¹⁵N₃ is the ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-W009162S4

Cytidine 5′-monophosphate-15N3 dilithium
Cytidine 5′-monophosphate- ¹⁵N₃ (5'-Cytidylic acid- ¹⁵N₃ dilithium; 5'-CMP- ¹⁵N₃) dilithium is ¹⁵N labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-W015913S

Sodium 2-oxopropanoate-13C3
Sodium 2-oxopropanoate- ¹³C₃ is the ¹³C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2].

HY-139145S

Etbicyphat-13C3
Etbicyphat- ¹³C₃ is the ¹³C labeled Etbicyphat (HY-139145). Etbicyphat is a potent GABA(A) receptors competitive antagonist. Etbicyphat induces epileptiform activities in hippocampal CA1 neurons, and binds to the GABA(A)-benzodiazepine receptors[1][2].

HY-12542S

Dantrolene-13C3

Dantrolene- ¹³C₃ is the ¹³C₃ labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.

HY-B0285AS

Amiloride-15N3 hydrochloride
Amiloride- ¹⁵N₃ (hydrochloride) is the ¹⁵N labeled Amiloride hydrochloride[1]. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC[2]) and urokinase-type plasminogen activator receptor (uTPA[3]). Amiloride hydrochloride is a blocker of polycystin-2 (PC2;TRPP2[4]) channel.

HY-W769714

Favipiravir-13C3
Favipiravir- ¹³C3 is the ¹³C labeled isotope of Favipiravir- ¹³C3(HY-14768 ).Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with an IC₅₀ of 341 nM.

HY-10020S

Varenicline-15N3 hydrochloride

Varenicline-15N3 Hydrochloride (CP 526555-15N3 Hydrochloride) is the ¹⁵N labeled isotope of Varenicline hydrochloride (HY-10020). Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC₅₀ = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation ^[3] .

HY-127035S1

Tristearin-13C3
Tristearin- ¹³C₃ (Glycerol tristearate- ¹³C₃) is ¹³C labeled Tristearin. Tristearin is a triglyceride derived from three units of stearic acid .

HY-W105860S

Guanidine-15N3 hydrobromide
Guanidine Hydrobromide- ¹⁵N₃ is the ¹⁵N labeled Guanidine Hydrobromide[1].

HY-B1204S2

Histamine-13C5, 15N3
Histamine- ¹³C₅, ¹⁵N₃ (Ergamine- ¹³C₅, ¹⁵N₃) is the ¹³C and ¹⁵N labeled isotope of Histamine (HY-B1204). Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter .

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