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SHIV C2/1

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715

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3

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6

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9

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7

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40

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202

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57

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36

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1517

    Aldose Reductase Cancer
    Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM [2].
    Ganoderic acid C2
  • HY-101180
    C2 Ceramide
    1 Publications Verification

    Ceramide 2

    Phosphatase Mitochondrial Metabolism Apoptosis Autophagy Metabolic Disease Endocrinology
    C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis, inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss [2] .
    C2 Ceramide
  • HY-N6910

    Others Metabolic Disease
    Pseudolaric Acid C2, a diterpenoid isolated from Pseudolarix kaempferi, is identified as the specific metabolite of Pseudolaric acid B in plasma, urine, bile and feces after both oral and intravenous administration to rats [2].
    Pseudolaric Acid C2
  • HY-W590664

    Endogenous Metabolite Cardiovascular Disease
    C2 Dihydroceramide is a derivative of C2 Ceramide (HY-101180). C2 Dihydroceramide enhances the ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I) without causing cytotoxicity .
    C2 Dihydroceramide
  • HY-138083

    Bacterial Antibiotic Infection
    Parvodicin C2 is a glycopeptide antibiotic that can be isolated from parvosata. Parvodicin C2 has antibacterial activity .
    Parvodicin C2
  • HY-N12297

    Others Others
    Ciwujianoside C2 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C2 enhances pancreatic lipase activity in vitro .
    Ciwujianoside C2
  • HY-N7521

    Procyanidine C2

    Others Others
    Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .
    Procyanidin C2
  • HY-126830

    Antifolate Apoptosis Cancer
    Antifolate C2 is an anti-folate compound that has inhibitory effects on the proliferation of non-squamous non-small cell lung cancer (NS-NSCLC). Antifolate C2 achieves tumor selectivity by targeting proton-coupled folate transporter (PCFT), which is more selective to PCFT than the commonly used anti-folate drug Pemetrexed (HY-10820). Antifolate C2 blocks the biosynthesis of deoxypurine nucleotides by inhibiting glycinamide ribonucleotide formyltransferase (GARFTase), ultimately inhibiting the proliferation of tumor cells. Antifolate C2 can be used in studies of NS-NSCLC, especially in patients who do not respond well to Pemetrexed .
    Antifolate C2
  • HY-130155

    AMPK Neurological Disease
    AMPK activator C2 is a potent allosteric AMPK activator that is promising for research of epilepsy and convulsions .
    AMPK activator C2
  • HY-165072

    C2 Sulfatide; N-Acetyl sulfatide

    Others Others
    C2 3'-Sulfo galactosylceramide (d18:1/2:0) (C2 Sulfatide) is one of the sulfatide class of glycolipids. C2 3'-Sulfo galactosylceramide (d18:1/2:0) can be used in the quantification of lysosulfatides in mouse brain tissue and plasma .
    C2 3'-Sulfo galactosylceramide (d18:1/2:0)
  • HY-RS01738

    Small Interfering RNA (siRNA) Others

    C2 Human Pre-designed siRNA Set A contains three designed siRNAs for C2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C2 Human Pre-designed siRNA Set A
    C2 Human Pre-designed siRNA Set A
  • HY-166226

    Others Metabolic Disease
    C2 Sphingomyelin (d18:1/2:0) is an ester product.
    C2 Sphingomyelin (d18:1/2:0)
  • HY-135868

    Mitochondrial Metabolism Neurological Disease
    Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect .
    Mito-apocynin (C2)
  • HY-N6980
    Licorice glycoside C2
    1 Publications Verification

    HIV Infection Cancer
    Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .
    Licorice glycoside C2
  • HY-116877

    COX Cancer
    C2 Ceramide (d14:1/2:0) is a composition for diagnosing diseases associated with cyclooxygenase 2 (COX2) overexpression. C2 Ceramide (d14:1/2:0) exhibits a strong binding activity to COX2 protein (extracted from patent WO2019235824A1).
    C2 Ceramide (d14:1/2:0)
  • HY-131992

    C2 Galactosylceramide (d18:1/2:0)

    Others Inflammation/Immunology
    N-Acetylpsychosine (C2 Galactosylceramide (d18:1/2:0)), α-galactosylated C2-ceramide, has immunostimulatory activity. N-Acetylpsychosine can be a useful tool to investigate the mechanism of apoptosis and the immune reponses induced by dendritic cells (DCs) .
    N-Acetylpsychosine
  • HY-165064

    L-Erythro cer(d18:1/2:0); N-Acetyl-L-erythro-sphingosine; Acetyl-L-erythro-sphingosine

    Others Cancer
    C2 L-Erythro ceramide (d18:1/2:0) is a cell-permeable sphingolipid. C2 L-Erythro ceramide (d18:1/2:0) induces cell cycle arrest in the G0/G1 phase and inhibits cell growth [2].
    C2 L-Erythro ceramide (d18:1/2:0)
  • HY-124273

    L-threo Cer(d18:1/2:0); L-threo Ceramide (d18:1/2:0); N-acetyl-L-threo-Sphingosine

    Endogenous Metabolite Cardiovascular Disease
    C2 L-threo Ceramide (d18:1/2:0) (L-threo Cer(d18:1/2:0); L-threo Ceramide (d18:1/2:0)) is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide. C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.
    C2 L-threo Ceramide (d18:1/2:0)
  • HY-P1182

    Histone Methyltransferase Cancer
    C21 is a potent, irreversible, and selective PRMT1 inhibitor with an IC50 of 1.8 μM. C21 inhibits PRMT6 with an IC50 of 8.8 μM .
    C21
  • HY-48394A

    Others Others
    Bis-S-C2-N(N-Me)-C2-OH (dihydrochloride) is an active compound. Bis-S-C2-N(N-Me)-C2-OH (dihydrochloride) can be used for various biochemical studies.
    Bis-S-C2-N(N-Me)-C2-OH dihydrochloride
  • HY-130713

    E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-C2-amido-C2-COOH incorporates a CRBN ligand for the E3 ubiquitin ligase, and a linker. Thalidomide-C2-amido-C2-COOH can be used to design PROTAC CDK2/9 Degrader-1 (HY-130709) .
    Thalidomide-C2-amido-C2-COOH
  • HY-148080

    ADC Linker Others
    Indole-C2-amide-C2-NH2 is a potent linker .
    Indole-C2-amide-C2-NH2
  • HY-130436

    PROTAC Linkers Cancer
    Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Acid-C2-PEG4-C2-NHS ester
  • HY-163078

    Others Cancer
    C2-Gal-Dox is a galactose conjugate with high cytotoxicity. C2-Gal-Dox inhibits the growth of a variety of cancer cells .
    C2-Gal-Dox
  • HY-161191

    Ligands for E3 Ligase Autophagy Cancer
    Thalidomide-azetidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-azetidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
    Thalidomide-azetidine-piperazine-C2-O-C2-OH
  • HY-W590667

    Biochemical Assay Reagents Others
    B27&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B27&"can be used in drug delivery research ."
    C2 Ceramide-1-phosphate
  • HY-140127

    ADC Linker Cancer
    Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azide-C2-SS-C2-biotin
  • HY-140101

    ADC Linker Cancer
    Azido-C2-SS-PEG2-C2-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-C2-SS-PEG2-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-C2-SS-PEG2-C2-acid
  • HY-157759

    Ligands for E3 Ligase Autophagy Cancer
    (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN proteins and serve as a key intermediate for the synthesis of complete PROTAC molecules.
    (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH
  • HY-123439

    Others Neurological Disease
    FTY720-C2 is a derivative of FTY72 (HY-12005). FTY720-C2 promotes the expression of brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) in multiple system atrophy (MSA) models, without causing immunosuppression. FTY720-C2 improves motor dysfunction and reduces the levels of insoluble alpha-synuclein (αSyn) in MSA mouse models. FTY720-C2 is blood-brain barrier penetrate .
    FTY720-C2
  • HY-N3671

    Others Others
    Cycloshizukaol A is a symmetrical cyclic lindenane dimer with C2 symmetry. Cycloshizukaol A can be isolated from the root of Chloranthus serratus .
    Cycloshizukaol A
  • HY-164210

    ADC Linker Cancer
    DBCO-PEG2-C2-acid is an ADC Linker. DBCO-PEG2-C2-acid can be used to synthesize Antibody-Drug Conjugates (ADCs) .
    DBCO-PEG2-C2-acid
  • HY-115384

    ADC Linker PROTAC Linkers Cancer
    Amino-PEG5-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    Amino-PEG5-C2-acid
  • HY-W040165

    ADC Linker PROTAC Linkers Cancer
    Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG3-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Amino-PEG3-C2-acid
  • HY-135928

    ADC Linker Cancer
    Biotin-C2-S-S-pyridine is a cleavable ADC linker. Biotin-C2-S-S-pyridine can be used in the synthesis of antibody-drug conjugates (ADCs) .
    Biotin-C2-S-S-pyridine
  • HY-148484

    Others Others
    Pomalidomide-5'-PEG5-C2-COOH is an active compound. Pomalidomide-5'-PEG5-C2-COOH can be used for the research of various biochemical .
    Pomalidomide-5'-PEG5-C2-COOH
  • HY-113697
    Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
    1 Publications Verification

    Mal-PEG2-AZD

    PROTAC Linkers Cancer
    Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (Mal-PEG2-AZD) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
  • HY-161197

    Ligands for E3 Ligase Autophagy Cancer
    Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
    Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C2-OH
  • HY-W040168

    ADC Linker PROTAC Linkers Cancer
    Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG2-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Amino-PEG2-C2-acid
  • HY-W584529

    E3 Ligase Ligand-Linker Conjugates Cancer
    VH032-C2-NH-Boc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C2-NH-Boc will remove the protecting group under acidic conditions, and can be directly used for the synthesis of PROTAC molecules. VH032-C2-NH-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands.
    VH032-C2-NH-Boc
  • HY-156304

    Fluorescent Dye Others
    Coumarin-C2-TCO is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
    Coumarin-C2-TCO
  • HY-130712

    PROTAC Linkers Cancer
    NH2-C2-amido-C2-Boc is a PROTAC linker, which refers to the alkyl/ether composition. NH2-C5-NH-Boc can be used in the synthesis of a series of PROTACs, such as the PROTAC CDK2/9 Degrader-1 (HY-130709) .
    NH2-C2-amido-C2-Boc
  • HY-126673

    ADC Linker Cancer
    Mal-C2-Gly3-EDA is a cleavable ADC linker containing a Maleimide group. Mal-C2-Gly3-EDA is used for making antibody-drug conjugate.
    Mal-C2-Gly3-EDA
  • HY-126512

    ADC Linker Cancer
    Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-C2-NHS ester
  • HY-130396

    PROTAC Linkers Cancer
    DBCO-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-C2-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-C2-acid
  • HY-148662

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-PEG5-C2-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG5-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-PEG5-C2-NH2 hydrochloride
  • HY-141662

    STING Drug-Linker Conjugates for ADC Inflammation/Immunology Cancer
    2’,3’-cGAMP-C2-PPA is a cyclic dinucleotide interferon gene-stimulating protein (STING) agonist. 2’,3’-cGAMP-C2-PPA is a drug conjugated conjugate used to target antibody-drug conjugated conjugate (ADC) for the treatment of cancer. 2’,3’-cGAMP-C2-PPA can be used in the study of immune and tumor-related diseases [2] .
    2',3'-cGAMP-C2-PPA
  • HY-W580022

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5'-PEG8-C2-COOH is an E3 Ligase Ligand-Linker Conjugates, consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-5'-PEG8-C2-COOH can be used for synthesis of PROTACs .
    Pomalidomide-5'-PEG8-C2-COOH
  • HY-40171S

    PROTAC Linker 22-d4

    PROTAC Linkers Cancer
    NH2-C2-NH-Boc-d4 is the deuterium labeled NH2-C2-NH-Boc[1]. NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs[2].
    NH2-C2-NH-Boc-d4
  • HY-141323

    PROTAC Linkers Cancer
    C2-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    C2-Bis-phosphoramidic acid diethyl ester

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