Search Result

Results for "

nitric oxide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	NO Synthase (143) Adrenergic Receptor (2) Akt (2) Aldehyde Dehydrogenase (ALDH) (1) AMPK (1) Angiotensin Receptor (3) Angiotensin-converting Enzyme (ACE) (3) Antibiotic (4) Apoptosis (31) Arginase (3) Autophagy (5) Bacterial (9) Bcl-2 Family (1) Biochemical Assay Reagents (3) c-Kit (2) Calcium Channel (6) Caspase (5) CD38 (1) CD47 (1) COX (18) Cuproptosis (2) DNA/RNA Synthesis (2) Dopamine Transporter (1) Drug Metabolite (2) EBV (3) Endogenous Metabolite (38) Epigenetic Reader Domain (1) ERK (2) Estrogen Receptor/ERR (1) Factor Xa (2) Fluorescent Dye (9) Fungal (3) Glucosidase (1) GLUT (1) Guanylate Cyclase (14) HDAC (2) Histamine Receptor (2) HIV Protease (1) HMG-CoA Reductase (HMGCR) (2) HSV (3) iGluR (2) IKK (1) Imidazoline Receptor (1) Indoleamine 2,3-Dioxygenase (IDO) (1) Interleukin Related (10) Isotope-Labeled Compounds (9) JAK (2) JNK (1) Keap1-Nrf2 (3) Lactate Dehydrogenase (1) Liposome (1) Lipoxygenase (2) MDM-2/p53 (1) Microtubule/Tubulin (5) Mitochondrial Metabolism (3) Monoamine Oxidase (6) nAChR (1) NADPH Oxidase (1) Neprilysin (1) NF-κB (23) NOD-like Receptor (NLR) (1) p38 MAPK (3) Parasite (6) PGE synthase (1) Phosphatase (1) Phosphodiesterase (PDE) (2) PKC (4) PKG (1) PPAR (2) Prostaglandin Receptor (2) Proteasome (2) Proton Pump (1) Pyruvate Kinase (1) RANKL/RANK (1) Reactive Oxygen Species (11) Ser/Thr Protease (1) Serotonin Transporter (2) STAT (1) STING (2) TGF-β Receptor (1) TNF Receptor (9) Toll-like Receptor (TLR) (5) Tyrosinase (1) VEGFR (2) Xanthine Oxidase (1) β-catenin (1)
By Research Areas:	Cancer (74) Cardiovascular Disease (59) Endocrinology (12) Infection (28) Inflammation/Immunology (130) Metabolic Disease (23) Neurological Disease (62)
Oligonucleotides:	Solubilizing Agents (1) Phospholipids (1)

310

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

116

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: NO Synthase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W011370

Pelargonidin chloride	Reactive Oxygen Species	Others
Pelargonidin chloride is a scavenger of nitric oxide radical and has antioxidant activities .

HY-N3473

Isomaculosidine	NO Synthase	Neurological Disease
Isomaculosidine is an alkaloid that can be isolated from D. dasycarpus. Isomaculosidine can inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 microglial cells .

HY-101394

Spermine NONOate	Others	Others
Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing .

HY-153056

BNN3	Others	Others
BNN3 is a caged nitric oxide (NO) donor. BNN3 is membrane-permeant and incorporated in the lipid membrane .

HY-N12139

Nitric oxide production-IN-1	NO Synthase	Cancer
Nitric oxide production-IN-1（Compound 1） is a inhibitor of NO Production which isolated from Tupistra chinensis. Nitric oxide production-IN-1（Compound 1） inhibits NO production in rat abdomen macrophages induced by lipopolysaccharide

HY-N10218

Sterpurol D	Others	Inflammation/Immunology
Sterpurol D is a compound of the sterpurane sesquiterpenoid. Sterpurol D significantly inhibits nitric oxide (NO) production .

HY-117601

11-Deoxyalisol B	Others	Inflammation/Immunology
11-Deoxyalisol B, a triterpene, shows the potent inhibitory activity on Lipopolysaccharide (LPS)-induced nitric oxide (NO) production .

HY-N2838

Alismol	NO Synthase	Inflammation/Immunology
Alismol is a natural sesquiterpene. Alismol shows promising inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells .

HY-N9092

Geranyl ferulate (E)-geranylferulic acid	NO Synthase	Infection Inflammation/Immunology
Geranyl ferulate ((E)-geranylferulic acid), isolated from Zingiber officinale, exhibits inhibitory effect on the production of nitric oxide (NO) .

HY-145882

BOD-NH-NP	Fluorescent Dye	Others
BOD-NH-NP is an activatable fluorescent probe for imaging endogenous nitric oxide via the eNOS enzymatic pathway .

HY-N3313

Masticadienolic acid	Others	Cancer
Masticadienolic acid is an antitumor agent via increasing the production of nitric oxide (NO). Masticadienolic acid also increases the release of NO in resting macrophages .

HY-116885

Thunalbene	Others	Inflammation/Immunology
Thunalbene is a stilbene derivative isolated from Thunia alba. Thunalbene has a weak inhibitory effect on nitric oxide production and is not cytotoxic .

HY-164361

2′-Hydroxy-2,3-dimethoxychalcone	NO Synthase	Inflammation/Immunology
α-Gracinoic acid is a Chalcone (HY-121054) derivative with anti-inflammatory activity. α-Gracinoic acid inhibits nitric oxide production catalyzed by inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-treated RAW 264.7 cells .

HY-N10217

Paneolilludinic acid	NO Synthase	Inflammation/Immunology
Paneolilludinic acid is a compound isolated from an endolichenic fungus Cryptomarasmius aucubae. Paneolilludinic acid significantly inhibits nitric oxide (NO) production .

HY-146309

iNOS-IN-2	NO Synthase	Inflammation/Immunology
iNOS-IN-2 (Compound 53) is a potent down-regulator of inducible nitric oxide synthase (iNOS) protein. iNOS-IN-2 effectively inhibits the NO production (IC₅₀=6.4 μM). iNOS-IN-2 has a potential therapeutic effect on chronic inflammation .

HY-N10214

(-)-10,11-Dihydroxyfarnesol	NO Synthase	Inflammation/Immunology
(-)-10,11-Dihydroxyfarnesol is a compound isolated from an endolichenic fungus Cryptomarasmius aucubae. (–)-10,11-Dihydroxyfarnesol significantly inhibits nitric oxide (NO) production .

HY-110275

RA839	Keap1-Nrf2	Others
RA839 is a noncovalent small molecule binder to Keap1 with a K_d of ∼6 μM and selective activator of Nrf2 signaling. RA839 prevents the induction of both inducible nitric-oxide synthase expression and nitric oxide release in response to lipopolysaccharides in macrophages. RA839 is a selective inhibitor of the Keap1/Nrf2 interaction and a useful tool compound to study the biology of Nrf2 .

HY-107546

CFM 1571 hydrochloride	Guanylate Cyclase	Cardiovascular Disease
CFM 1571 hydrochloride is the stimulator of the nitric oxide receptor, soluble guanylate cyclase (sGC) with an EC₅₀ and IC₅₀ of 5.49 μM and 2.84 μM, respectively. Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). CFM 1571 hydrochloride has the potential for the research of cardiovascular and other diseases .

HY-P10159

DJK-5	Bacterial	Infection
Diplacol ia a natural compound from from Mimulus clevelandi and shows potent inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide production .

HY-N10857

12-Hydroxymyricanone	Others	Others
12-Hydroxymyricanone is a nature product that could be isolated from the roots of Myrica nana. 12-Hydroxymyricanone inhibits the release of nitric oxide with an IC₅₀ value of 30.19 μM .

HY-12124

BBS-4	NO Synthase	Cardiovascular Disease
BBS-4 is a potent and selective inducible nitric oxide synthase (NOS2) dimerization inhibitor, with an IC₅₀ of 0.49 nM. BBS-4 can protect mice from the cardiovascular dysfunction of sepsis .

HY-155551

Anti-inflammatory agent 46	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 46 (compound 7h) is an anti-inflammatory agent with nitric oxide (NO) inhibitory effect. Anti-inflammatory agent 46 binds to iNOS with low energies, inhibits swelling in mice (at dose of 10 mg/kg) .

HY-N1695

Demethylregelin Regelin acid	NO Synthase	Inflammation/Immunology
Demethylregelin (Regelin acid), a triterpene, effectively reduces the expression of iNOS protein and subsequent nitric oxide production induced by lipopolysaccharide (HY-D1056) in RAW264.7 cells. Demethylregelin has anti-inflammatory activities .

HY-N8129

Rhaponticin 6′′-O-gallate	Others	Others
Rhaponticin 6′′-O-gallate is a stilbene glucoside gallate that can be found in rhizome of Rheum undulatum L. Rhaponticin 6′′-O-gallate inhibits nitric oxide production in lipopolysaccharide-activated macrophages .

HY-N10212

Dendryphiellin D	Fungal	Infection
Dendryphiellin D is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Dendryphiellin D significantly inhibits the production of nitric oxide (NO) .

HY-N10213

Septeremophilane E	NO Synthase	Infection
Septeremophilane E is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Septeremophilane E significantly inhibits the production of nitric oxide (NO) .

HY-134221

S-Nitroso-N-acetylcysteine	Others	Cardiovascular Disease
S-Nitroso-N-acetylcysteine is a nitric oxide donor. S-Nitroso-N-acetylcysteine has a tissue vascular dilation effect, which can enhance liver microcirculation and effectively prevent ischemia-reperfusion injury in fatty liver. S-Nitroso-N-acetylcysteine can reduce liver fibrosis in rats with cirrhosis .

HY-N8812

19-[(β-D-Glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide	NO Synthase	Inflammation/Immunology
19-[(β-D-Glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide, the metabolite of Neoandrographolide, inhibits nitric oxide (NO) production in lipopolysaccharide-activated macrophages .

HY-149339

hnNOS-IN-2	NO Synthase	Neurological Disease
hnNOS-IN-2 (compound 17) is a human neuronal nitric oxide synthase (hnNOS) inhibitor with good metabolic stability. hnNOS-IN-2 can be used for research in neurodegenerative diseases .

HY-P4523

FA-Ala-Arg	Endogenous Metabolite	Endocrinology
FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells .

HY-155182

HDAC-IN-62	HDAC Autophagy	Neurological Disease Inflammation/Immunology
HDAC-IN-62 (Compound 5) a HDAC inhibitor, with IC₅₀s of 0.78, 1.0, 1.2? μM for HDAC6/8/11 respectively. HDAC-IN-62 inhibits-induced microglial activation by the initiation of autophagy, and inhibits nitric oxide production. HDAC-IN-62 has anti-inflammatory and anti-depressant effects. HDAC-IN-62 inhibits microglial activation in mouse brain .

HY-N11657

Sanggenon A Sanggenone A	NF-κB Keap1-Nrf2	Inflammation/Immunology
Sanggenon A (Sanggenone A) exerts anti-inflammatory effects by regulating NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells. Sanggenon A markedly inhibits the Lipopolysaccharide (LPS; HY-D1056)-induced production of nitric oxide .

HY-145846

iNOs-IN-1 1 Publications Verification	NO Synthase Interleukin Related	Inflammation/Immunology
iNOs-IN-1 (YPW) is a potent inducible nitric oxide synthase (iNOS) inhibitor. iNOs-IN-1 can significantly inhibit the expression of IL-6 and iNOS, as well as reduce LPS-induced NO generation with dose-dependent manner in mouse macrophages. Anti-inflammatory effects .

HY-N12224

1-Heptadecanoyl-rac-glycerol MG(17:0/0:0/0:0); 1-Heptadecanoin	NO Synthase	Inflammation/Immunology
1-Heptadecanoyl-rac-glycerol (1-Heptadecanoin) is a glyceride compound with anti-inflammatory activity. 1-Heptadecanoyl-rac-glycerol inhibits the occurrence of inflammation by suppressing the expression of *inducible nitric* oxide synthase (iNOS**) related to inflammation. 1-Heptadecanoyl-rac-glycerol can be used for research on diseases related to inflammation .

HY-W013435

1,2-Diaminoanthraquinone	Fluorescent Dye	Others
1,2-Diaminoanthraquinone is a sensitivity, specificity and nontoxic **nitric oxide** (NO) fluorescent probe. 1,2-Diaminoanthraquinone can be used to detect NO productions in live cell and animals with a maximum of absorption at about 540 nm and a detection limit of 5 μM for NO .

HY-145607

Zagociguat CY-6463; IW-6463	Guanylate Cyclase	Cardiovascular Disease
Zagociguat is the stimulator of soluble guanylate cyclase. Zagociguat increases nitric oxide (NO) signaling leading to an increase in cyclic guanosine monophosphate production. Zagociguat has the potential for the research of noncentral nervous system (CNS) disorders .

HY-N3426

Kazinol B	NO Synthase Akt AMPK	Metabolic Disease
Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research .

HY-139419

Bimatoprost grenod NCX 470	Prostaglandin Receptor	Cardiovascular Disease Neurological Disease
Bimatoprost grenod (NCX 470) is a second-generation nitric oxide (NO)-donating prostaglandin analogue. Bimatoprost grenod effectively lowers intraocular pressure (IOP) in animal models of ocular hypertension and glaucoma by activating bimatoprost-mediated uveoscleral outflow and NO mediated conventional outflow. Bimatoprost grenod can be used for the research of cular hypertension and glaucoma .

HY-160424

DEANO sodium Diethylamine NONOate sodium; Diethylamine nitric oxide sodium	Others	Others
DEANO sodium is notric oxide donor. DEANO sodium potentiates the abilitv of hypoxanthine/xanthine oxidase to induce lipid peroxidation as well as DNA single- and double-strand breaks .

HY-163478

TNIK-IN-9	NF-κB	Inflammation/Immunology
TNIK-IN-9 (Compound 54) is a selective and potent NIK inhibitor, with an IC₅₀ of 1.27 nM. TNIK-IN-9 can inhibit pro-inflammatory cytokines and nitric oxide production. TNIK-IN-9 exhibits significant anti-inflammatory effects, improved mortality, and hepatoprotective effects in sepsis models .

HY-B0300

Penicillamine 2 Publications Verification D-(-)-Penicillamine	Cuproptosis Drug Metabolite	Inflammation/Immunology Cancer
Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine reduces free copper and reduces oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria .

HY-153092

Avenciguat BI-685509	Guanylate Cyclase	Cardiovascular Disease Metabolic Disease
Avenciguat (BI-685509) is a potent and orally active sGC activator. Avenciguat restores cyclic guanosine monophosphate (cGMP) and improves functionality of nitric oxide (NO) pathways. Avenciguat can be used in research of chronic kidney disease (CKD) and diabetic kidney disease (DKD) .

HY-N11085

Isophysalin A	NO Synthase IKK	Inflammation/Immunology
Isophysalin A is a physalin with alpha and beta unsaturated ketone components. Isophysalin A binds to GSH and targets multiple cysteine residues on IKKβ. Isophysalin A also inhibits inducible NO synthase (iNOS) and nitric oxide (NO) production, showing anti-inflammatory activity .

HY-136278

DETA NONOate 3 Publications Verification Diethylamine NONOate; NOC-18	NO Synthase	Cardiovascular Disease
DETA NONOate (NOC 18) is an exogenous **nitric oxide (NO)** donor. DETA NONOate shows a slow release normal amounts of NO and long-acting .

HY-B0300R

Penicillamine (Standard)	Cuproptosis Drug Metabolite	Inflammation/Immunology Cancer
Penicillamine (Standard) is the analytical standard of Penicillamine. This product is intended for research and analytical applications. Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine reduces free copper and reduces oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria .

HY-103385

NCX4040 NO-Aspirin	Apoptosis	Inflammation/Immunology Cancer
NCX4040 (NO-Aspirin), a non-steroidal anti-inflammatory drug (NSAID), is a nitric oxide (NO) releasing form of Aspirin. NCX4040 induces apoptosis in PC3 metastatic prostate cancer cells. NCX4040 has anti-inflammatory and anti-cancer effects .

HY-117607

Alatrioprilat	Neprilysin Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Alatrioprilat is an orally active inhibitor of angiotensin-converting enzyme (ACE) (IC₅₀=19.6 nM; K_i=9.8 nM) and enkephailnase (IC₅₀=6.1 nM; K_i=5.1 nM). Alatrioprilat plays a key role in the metabolism of hormonal peptides through the degradation of nitric oxide and atrial natriuretic factor (ANF). Alatrioprilat can be used in the study of cardiovascular diseases .

HY-15509A

Semapimod tetrahydrochloride 2 Publications Verification CNI-1493; CPSI-2364 tetrahydrochloride	TNF Receptor Interleukin Related p38 MAPK	Inflammation/Immunology Cancer
Semapimod tetrahydrochloride (CNI-1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF-α, IL-1β, and IL-6. Semapimod tetrahydrochloride inhibits TLR4 signaling (IC₅₀≈0.3 μM). Semapimod tetrahydrochloride inhibits p38 MAPK and nitric oxide production in macrophages. Semapimod tetrahydrochloride has potential in a variety of inflammatory and autoimmune disorders .

HY-W062836

BAY 41-8543	Guanylate Cyclase	Cardiovascular Disease
BAY 41-8543 is an orally active, nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC). BAY 41-8543 has vasodilator activity in the pulmonary and systemic vascular beds in the rat. BAY 41-8543 has antiplatelet effects and has the potential for cardiovascular diseases research .

HY-U00432B

S-MTC acetate S-Methyl-L-thiocitrulline acetate	Others	Inflammation/Immunology
S-MTC acetate (S-Methyl-L-thiocitrulline acetate) acts as a powerful inhibitor of inducible nitric oxide synthase, favoring the inhibition of constitutive (neuronal) nitric oxide synthase over inducible (endothelial) nitric oxide synthase.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W011370

Pelargonidin chloride	Anthocyans Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Plants Phaseolus vulgaris Linn. Disease Research Fields	Reactive Oxygen Species
Pelargonidin chloride is a scavenger of nitric oxide radical and has antioxidant activities .

HY-N3473

Isomaculosidine	Alkaloids Dictamnus dasycarpus Turcz. Source classification Rutaceae Quinoline Alkaloids Plants	NO Synthase
Isomaculosidine is an alkaloid that can be isolated from D. dasycarpus. Isomaculosidine can inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 microglial cells .

HY-N12139

Nitric oxide production-IN-1	Structural Classification Source classification Plants Rohdea chinensis (Baker) N.Tanaka Saccharides Monosaccharides Asparagaceae Juss.	NO Synthase
Nitric oxide production-IN-1（Compound 1） is a inhibitor of NO Production which isolated from Tupistra chinensis. Nitric oxide production-IN-1（Compound 1） inhibits NO production in rat abdomen macrophages induced by lipopolysaccharide

HY-N10218

Sterpurol D	Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields Inflammation/Immunology	Others
Sterpurol D is a compound of the sterpurane sesquiterpenoid. Sterpurol D significantly inhibits nitric oxide (NO) production .

HY-N2838

Alismol	Structural Classification Animals Terpenoids Sesquiterpenes Source classification	NO Synthase
Alismol is a natural sesquiterpene. Alismol shows promising inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells .

HY-N9092

Geranyl ferulate (E)-geranylferulic acid	Zingiber officinale Roscoe Monophenols Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology Zingiberaceae	NO Synthase
Geranyl ferulate ((E)-geranylferulic acid), isolated from Zingiber officinale, exhibits inhibitory effect on the production of nitric oxide (NO) .

HY-N3313

Masticadienolic acid	Triterpenes Structural Classification Amphipterygium adstringens (Schltdl.) Schiede ex Standl. Ketones, Aldehydes, Acids Terpenoids Source classification Plants Anacardiaceae	Others
Masticadienolic acid is an antitumor agent via increasing the production of nitric oxide (NO). Masticadienolic acid also increases the release of NO in resting macrophages .

HY-116885

Thunalbene	Structural Classification Orchidaceae Thunia alba (Lindl.) Rchb. F. Source classification Phenols Plants	Others
Thunalbene is a stilbene derivative isolated from Thunia alba. Thunalbene has a weak inhibitory effect on nitric oxide production and is not cytotoxic .

HY-N10217

Paneolilludinic acid	Structural Classification Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Inflammation/Immunology Disease Research Fields	NO Synthase
Paneolilludinic acid is a compound isolated from an endolichenic fungus Cryptomarasmius aucubae. Paneolilludinic acid significantly inhibits nitric oxide (NO) production .

HY-N10214

(-)-10,11-Dihydroxyfarnesol	Structural Classification Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Inflammation/Immunology Disease Research Fields	NO Synthase
(-)-10,11-Dihydroxyfarnesol is a compound isolated from an endolichenic fungus Cryptomarasmius aucubae. (–)-10,11-Dihydroxyfarnesol significantly inhibits nitric oxide (NO) production .

HY-N10857

12-Hydroxymyricanone	Structural Classification Natural Products Source classification Plants Morella adenophora (Hance) J. Herb. Myricaceae	Others
12-Hydroxymyricanone is a nature product that could be isolated from the roots of Myrica nana. 12-Hydroxymyricanone inhibits the release of nitric oxide with an IC₅₀ value of 30.19 μM .

HY-N1695

Demethylregelin Regelin acid	Structural Classification Terpenoids Source classification Celastraceae Plants Pentacyclic Triterpenoids Euonymus alatus (Thunb.) Sieb.	NO Synthase
Demethylregelin (Regelin acid), a triterpene, effectively reduces the expression of iNOS protein and subsequent nitric oxide production induced by lipopolysaccharide (HY-D1056) in RAW264.7 cells. Demethylregelin has anti-inflammatory activities .

HY-N8129

Rhaponticin 6′′-O-gallate	Structural Classification Stilbenes Classification of Application Fields Polygonaceae Source classification Rheum rhabarbarum Linnaeus Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Rhaponticin 6′′-O-gallate is a stilbene glucoside gallate that can be found in rhizome of Rheum undulatum L. Rhaponticin 6′′-O-gallate inhibits nitric oxide production in lipopolysaccharide-activated macrophages .

HY-N10212

Dendryphiellin D	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal
Dendryphiellin D is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Dendryphiellin D significantly inhibits the production of nitric oxide (NO) .

HY-N10213

Septeremophilane E	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	NO Synthase
Septeremophilane E is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Septeremophilane E significantly inhibits the production of nitric oxide (NO) .

HY-N11657

Sanggenon A Sanggenone A	Structural Classification Flavonoids Source classification Morus alba L. Plants Moraceae Other Flavonoids	NF-κB Keap1-Nrf2
Sanggenon A (Sanggenone A) exerts anti-inflammatory effects by regulating NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells. Sanggenon A markedly inhibits the Lipopolysaccharide (LPS; HY-D1056)-induced production of nitric oxide .

HY-N12224

1-Heptadecanoyl-rac-glycerol MG(17:0/0:0/0:0); 1-Heptadecanoin	Apocynaceae Structural Classification Natural Products Source classification Plants Trachelospermum jasminoides (Lindl.) Lem.	NO Synthase
1-Heptadecanoyl-rac-glycerol (1-Heptadecanoin) is a glyceride compound with anti-inflammatory activity. 1-Heptadecanoyl-rac-glycerol inhibits the occurrence of inflammation by suppressing the expression of *inducible nitric* oxide synthase (iNOS**) related to inflammation. 1-Heptadecanoyl-rac-glycerol can be used for research on diseases related to inflammation .

HY-N3426

Kazinol B	Structural Classification other families Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	NO Synthase Akt AMPK
Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research .

HY-B0300

Penicillamine 2 Publications Verification D-(-)-Penicillamine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Inflammation/Immunology Disease Research Fields	Cuproptosis Drug Metabolite
Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine reduces free copper and reduces oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria .

HY-N11085

Isophysalin A	Structural Classification Natural Products Source classification Plants Solanaceae Alkekengi officinarum Moench	NO Synthase IKK
Isophysalin A is a physalin with alpha and beta unsaturated ketone components. Isophysalin A binds to GSH and targets multiple cysteine residues on IKKβ. Isophysalin A also inhibits inducible NO synthase (iNOS) and nitric oxide (NO) production, showing anti-inflammatory activity .

HY-B0300R

Penicillamine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Cuproptosis Drug Metabolite
Penicillamine (Standard) is the analytical standard of Penicillamine. This product is intended for research and analytical applications. Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine reduces free copper and reduces oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria .

HY-W074890

Palmitoylglycine N-palmitoyl glycine	Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Calcium Channel NO Synthase
Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA .

HY-N9814

Shanciol B	Pholidota imbricata Hook. Classification of Application Fields Orchidaceae Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	NO Synthase
Shanciol B, isolated from the ethyl acetate extract of the air-dried whole plant of Pholidota imbricate Hook, inhibits nitric oxide (NO) production and 1,1-diphenyl-2-picrylhydrazil (DPPH) radical scavenging activity . Shanciol B is a microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with anti-inflammatory activity .

HY-N4155

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid	Rosaceae Rosa cymosa (L.) Tratt. Plants	EBV HIV Protease HSV
2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides)-activated RAW 264.7 cells .

HY-N0617

Sanggenon C 2 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Plants Moraceae Flavanonols Flavonoids Phenols Polyphenols Inflammation/Immunology Disease Research Fields Morus alba Linn.	Phosphatase ERK NF-κB Apoptosis
Sanggenon C, a flavonoid, exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits mitochondrial fission to induce apoptosis by blocking the ERK signaling pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and TNF-α-stimulated cell adhesion and VCAM-1 expression, by suppressing NF-κB activity. Sanggenon C possesses antioxidant, anti-inflammatory and antitumor activities .

HY-A0129

Histamine phosphate 5+ Cited Publications Histamine diphosphate	Alkaloids Structural Classification Neurological Disease Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Endocrinology Cancer	Histamine Receptor Endogenous Metabolite
Histamine (phosphate) is a strong histamine receptor activator and vasodilator neuroagent, capable of activating nitric oxide synthase.

HY-125458

Iromycin A	Structural Classification Natural Products Microorganisms Source classification	NO Synthase
Iromycin A is a potent inhibitor of nitric oxide synthases (NO synthase) that can be isolated from Streptomyces sp. .

HY-N1317

Salirepin	Monophenols Source classification Melia azedarach L. Phenols Plants Meliaceae	Others
Salirepin is a phenolic glycoside from fruits of Idesia polycarpa, inhibits LPS-induced nitric oxide production .

HY-N4207

Cnidicin	Structural Classification Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Umbelliferae Plants Disease Research Fields Echinacea angustifolia DC.	Others
Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells .

HY-113216

Asymmetric dimethylarginine 2 Publications Verification NG,NG-Dimethylarginine	Cardiovascular Disease Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite NO Synthase
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states.

HY-N0455

L-Arginine 5+ Cited Publications	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Amino acids Endogenous metabolite Disease Research Fields Cancer	NO Synthase Endogenous Metabolite
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N0455A

L-Arginine hydrochloride 5+ Cited Publications (S)-(+)-Arginine hydrochloride	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	NO Synthase Endogenous Metabolite
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N8759

Vogeloside	Structural Classification Caprifoliaceae Triosteum pinnatifidum Maxim. Source classification Plants Saccharides Monosaccharides	Others
Vogeloside is an iridoid that can be isolated from the roots of Triosteum pinnatifidum. Vogeloside inhibits nitric oxide production in LPS-activated macrophages .

HY-107383

Tetrahydrobiopterin (Rac)-Sapropterin	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Disease markers Endogenous metabolite Inflammation/Immunology Disease Research Fields Cardiovascular System Disorder	NO Synthase Endogenous Metabolite
Tetrahydrobiopterin ((Rac)-Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.

HY-N2300

Kuwanon A 1 Publications Verification	Structural Classification Classification of Application Fields Flavones Source classification Metabolic Disease Plants Moraceae Flavonoids other families Phenols Polyphenols Morus alba L. Inflammation/Immunology Disease Research Fields	NO Synthase
Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC₅₀ of 10.5 μM.

HY-N10416

Neuroinflammatory-IN-1	Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology	Others
Neuroinflammatory-IN-1 (Compound 5) is an anti-neuroinflammatory agent and displays inhibitory effect on nitric oxide (NO) production with an IC₅₀ value of 65.4 μM .

HY-N9675

(+)-Hannokinol	Structural Classification Amomum tsaoko Crevost et Lemarie Source classification Phenols Polyphenols Plants Zingiberaceae	NO Synthase
(+)-Hannokinol can be isolated from AMOMUM TSAO-KO (ginger family) fruit. (+)-Hannokinol inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglia .

HY-133098

Juncutol	Juncaceae Source classification Plants Juncus acutus L.	NO Synthase
Juncutol is a potent *inducible nitric* oxide synthase (iNOS)** inhibitor. Juncutol decreases the LPS (HY-D1056)-stimulated iNOS protein expression .

HY-101238

Agmatine sulfate	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Imidazoline Receptor NO Synthase Endogenous Metabolite
Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor.

HY-N9896

Anhydronotoptol	Structural Classification Natural Products Source classification Plants Umbelliferae Kleinia odora (Forssk.) DC.	NO Synthase
Anhydronotoptol is a potent nitric oxide inhibitory coumarin. Anhydronotoptol inhibits NO production in RAW 264.7 cells induced by LPS with an IC₅₀ value of 36.6 μM .

HY-N0455R

L-Arginine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	NO Synthase Endogenous Metabolite
L-Arginine (Standard) is the analytical standard of L-Arginine. This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N0455AR

L-Arginine hydrochloride (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	NO Synthase Endogenous Metabolite
L-Arginine (hydrochloride) (Standard) is the analytical standard of L-Arginine (hydrochloride). This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-101410

SDMA Symmetric dimethylarginine; NG,NG'-Dimethyl-L-arginine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other disease Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.

HY-N3245

Moracin C 1 Publications Verification	Structural Classification Source classification Phenols Polyphenols Plants Moraceae	Reactive Oxygen Species COX
Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells .

HY-A0129R

Histamine phosphate (Standard)	Alkaloids Structural Classification Other Alkaloids Source classification Endogenous metabolite	Histamine Receptor Endogenous Metabolite
Histamine (phosphate) (Standard) is the analytical standard of Histamine (phosphate). This product is intended for research and analytical applications. Histamine (phosphate) is a strong histamine receptor activator and vasodilator neuroagent, capable of activating nitric oxide synthase.

HY-N6770

Curvularin (S)-Curvularin	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Disease Research Disease Research Fields	NO Synthase
Curvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC₅₀ of 9.5 µM .

HY-N1382

Asperuloside 2 Publications Verification	Structural Classification Iridoids Classification of Application Fields Terpenoids Source classification Rubiaceae Plants Inflammation/Immunology Disease Research Fields Hedyotis diffusa Willd.	NO Synthase
Asperuloside is an iridoid isolated from Hedyotis diffusa, with anti-inflammatory activity. Asperuloside inhibits inducible nitric oxide synthase (iNOS), suppresses NF-κB and MAPK signaling pathways .

HY-N1080

Vitexdoin A	Structural Classification Verbenaceae Source classification Lignans Phenylpropanoids Plants Vitex negundo Linn.	Others
Vitexdoin A is a nitric oxide scavenging lignin. Vitexdoin A inhibits NO production with an IC₅₀ of 0.38 μM in LPS (HY-D1056)-stimulated RAW 264.7 cells .

HY-N4207R

Cnidicin (Standard)	Structural Classification Source classification Coumarins Phenylpropanoids Umbelliferae Plants Echinacea angustifolia DC.	Others
Cnidicin (Standard) is the analytical standard of Cnidicin. This product is intended for research and analytical applications. Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells .

HY-N9376

Kansuinine E	Classification of Application Fields Terpenoids Source classification Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology	Others
Kansuinine E is a plant-derived **nitric oxide inhibitor (IC₅₀**=6.3 μM). Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui .

Cat. No.	Product Name	Chemical Structure

HY-101410S

SDMA-d6
SDMA-d₆ is the deuterium labeled SDMA. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity[1][2].

HY-N0455AS2

L-Arginine-d7 hydrochloride
L-Arginine-d₇ (hydrochloride) is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS7

L-Arginine-13C hydrochloride
L-Arginine- ¹³C (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS

L-Arginine-15N2 hydrochloride 1 Publications Verification
L-Arginine- ¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS6

L-Arginine-13C6 hydrochloride
L-Arginine- ¹³C₆ (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS1

L-Arginine-15N4 hydrochloride
L-Arginine- ¹⁵N₄ (hydrochloride) is the ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis[1].

HY-N0455AS5

L-Arginine-1,2-13C2 hydrochloride
L-Arginine-1,2- ¹³C₂ (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS8

L-Arginine-13C6,15N4 hydrochloride
L-Arginine- ¹³C₆, ¹⁵N₄ (hydrochloride) is the ¹³C- and ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-113216S

Asymmetric dimethylarginine-d7 hydrochloride hydrate
Asymmetric dimethylarginine-d₇ (hydrochloride hydrate) is the deuterium labeled Asymmetric dimethylarginine. Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a num

HY-N0455AS3

L-Arginine-1-13C hydrochloride
L-Arginine-1- ¹³C (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS9

L-Arginine-15N4,d7 hydrochloride
L-Arginine- ¹⁵N₄,d₇ (hydrochloride) is the deuterium and ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS4

L-Arginine-13C6,15N4,d7 hydrochloride
L-Arginine- ¹³C₆, ¹⁵N₄,d₇ (hydrochloride) is the deuterium, ¹³C-, and 15-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-B0503S

2-Thiouracil-13C,15N2
2-Thiouracil- ¹³C, ¹⁵N₂ is the ¹³C, ¹⁵N labeled 2-Thiouracil. 2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM.

HY-B1448AS

(Rac)-Benidipine-d7
(Rac)-Benidipine-d₇ is the deuterium labeled Benidipine[1]. Benidipine is a potent and orally active calcium channel antagonist[2]. Benidipine shows anti-apoptosis effects in ischaemic/reperfused myocardial cells[3]. Benidipine increases the activity of endothelial cell-type nitric oxide synthase and improves coronary circulation in hypertensive rats[4].

HY-78131S2

Ibuprofen-d4
Ibuprofen-d₄ is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[2][3][4][5].

HY-N0455AS11

L-Arginine-13C6,d14 hydrochloride
L-Arginine-13C6,d14 hydrochloride ((S)-(+)-Arginine-13C6,d14 hydrochloride) is a deuterated derivative of L-Arginine hydrochloride (HY-N0455A) that is labeled with ¹³C6. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) serves as a nitrogen donor for the synthesis of nitric oxide and is a vasodilator .

HY-78131S3

Ibuprofen-13C6

Ibuprofen- ¹³C₆ ((±)-Ibuprofen- ¹³C₆) is a ¹³C labeled Ibuprofen (HY-78131). Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC₅₀ value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .

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