Parasite

Parasite

Parasite

Related Products

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison

Parasite Related Products (1917)
Parasite Isoform Comparison

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By Effects:	Controls (10) Inhibitors (1582) Agonist (1) Antagonist (1) Activators (2) Modulators (3)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-149289

DNMT-IN-3	Inhibitor
DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC₅₀ of 60 nM against Plasmodium falciparum (Plasmodium). DNMT-IN-3 can be used for malaria related research.

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Inhibitor
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively.

HY-172206

TSO-13	Inhibitor
TSO-13 is the inhibitor for the main cysteine protease of Trypanosoma cruzi Cruzipain with an IC₅₀ of 2.2 μM. TSO-13 inhibits T. cruzi in Vero cell with an IC₅₀ of 1.9 μM.

HY-B1064R

Clindamycin phosphate (Standard)	Inhibitor
Clindamycin phosphate (Standard) is the analytical standard of Clindamycin phosphate. This product is intended for research and analytical applications. Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate can be used for researching acne and bacterial vaginosis.

HY-D1532

DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite.

HY-149960

Antiparasitic agent-17	Inhibitor
Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC₅₀s of 0.96 μM and 1.67 μM, respectively.

HY-A0163CR

trans-Clopenthixol (dihydrochloride) (Standard)	Inhibitor

HY-146043

Antiparasitic agent-5	Inhibitor
Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC₅₀ = 6.78 μM).

HY-130993

Isatropolone A	Inhibitor
Isatropolone A, a natural product containing a 1,5-diketone moiety, is reisolated from Streptomyces G 66. Isatropolone A shows potent activity against *Leishmania donovani* with an IC₅₀ of 0.5 μM.

HY-138050

Nyasol	Inhibitor
Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells.

HY-127087

Isogarcinol	Inhibitor
Isogarcinol (Cambogin) is a potent AChE and BChE inhibitor, with IC₅₀ values of 1.13 and 8.30 μM, respectively. Isogarcinol also shows leishmanicidal activity, with an IC₅₀ of 0.33 μM against L. donovani.

HY-116535A

DL-threo-PPMP hydrochloride
DL-threo-PPMP hydrochloride is an inhibitor of sphingosine synthetase in Plasmodium falciparum. DL-threo-PPMP hydrochloride inhibits the activity of sphingosine synthetase (sphingosine synthetase) by binding to a substrate that mimics sphingosine. This inhibition leads to a rapid decline in sensitive sphingomyelin synthase (SSS) activity, selectively disrupting the interconnected tubular network of TVM in the cytoplasm of the host cell, and this inhibition also blocks the proliferation of the parasite. DL-threo-PPMP hydrochloride can be used in the study of malaria parasite biology and the search for new antimalarial strategies.

HY-17598S

Rafoxanide-¹³C₆	Inhibitor
Rafoxanide ¹³C₆ is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent[1].

HY-143409

Antimalarial agent 10
Antimalarial agent 10 (Compound 17b) is an aminoalcohol quinoline compound. Antimalarial agent 10 is an antimalarial agent with IC₅₀ values of 14.9 nM and 11.0 nM against respectively Pf3D7 and PfW2 and a selectivity index higher than 770 whatever the cell line is.

HY-17598R

Rafoxanide (Standard)	Inhibitor
Rafoxanide (Standard) is the analytical standard of Rafoxanide. This product is intended for research and analytical applications. Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein, which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research.

HY-B1198R

Piperonyl butoxide (Standard)	Inhibitor
Piperonyl butoxide (Standard) is the analytical standard of Piperonyl butoxide. This product is intended for research and analytical applications. Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and ATF-2 in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice.

HY-B0497G

Niclosamide (GMP)	Inhibitor
Niclosamide (GMP) is Niclosamide (HY-B0497) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research. Niclosamide is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells. Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells.

HY-13557R

Ascomycin (Standard)	Inhibitor

HY-N6816

Ludaconitine	Inhibitor
Ludaconitine, isolated from Aconitum spicatum (Bruhl) Stapf, exhibits antileishmanial activity with an IC₅₀ of 36.10 μg/mL.

HY-148180

Antimycobacterial agent-4	Inhibitor	≥98.0%
Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line.

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