Search Result
Results for "
Boc
" in MedChemExpress (MCE) Product Catalog:
1110
Inhibitors & Agonists
76
Biochemical Assay Reagents
13
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P2237
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- HY-P1795
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- HY-P2008
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IEGR-AMC
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Factor Xa
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Cardiovascular Disease
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Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .
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- HY-W753820A
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Boc-Leu-Arg-Arg-AMC TFA
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Biochemical Assay Reagents
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Others
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Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
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- HY-115391
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Boc-Leu-Arg-Arg-AMC
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Biochemical Assay Reagents
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Others
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Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
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- HY-W013781
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Biochemical Assay Reagents
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Others
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Boc-Glu(OBzl)-OH (Compound 9) is a glutamic acid derivative commonly used in Boc SPPS. Glutamic acid residues increase the hydrophilicity of the polypeptide and play an important structural and receptor binding role .
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- HY-P5834
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- HY-P2669
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- HY-P10060
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- HY-138335
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PROTAC Linkers
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Cancer
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Boc-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138473
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PROTAC Linkers
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Cancer
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Boc-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W048332
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- HY-W008919
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N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester
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Amino Acid Derivatives
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Others
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Boc-Lys(Boc)-Onp (N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester) is a lysine with a Boc protecting group. Boc-Lys(Boc)-Onp was used as a substrate for a catalyst model to study its enzymatic hydrolysis reaction catalyzed by a copper(II) complex .
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- HY-W088151
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- HY-140420
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PROTAC Linkers
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Cancer
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Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140613
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PROTAC Linkers
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Cancer
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Boc-PEG4-sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138370
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PROTAC Linkers
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Cancer
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Boc-NH-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-41121
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Boc-Ala-OH
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Amino Acid Derivatives
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Others
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Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein .
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- HY-41912B
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Boc-D-Nle-OH; N-Boc-D-norleucine
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Amino Acid Derivatives
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Others
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Boc-D-norleucine (Boc-D-Nle-OH) is a leucine derivative that can be used for peptide synthesis .
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- HY-W101495
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N-Boc-L-leucine monohydrate
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Amino Acid Derivatives
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Others
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Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .
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- HY-141198
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PROTAC Linkers
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Cancer
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Boc-NH-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138494
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PROTAC Linkers
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Cancer
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Boc-NH-PEG12-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W007743
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Boc-L-pipecolic acid
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Biochemical Assay Reagents
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Others
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Boc-Pip-OH (Boc-L-pipecolic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W077219
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Boc-Arg(Mtr)-OH
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Amino Acid Derivatives
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Others
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Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
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- HY-W002299
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Boc-D-Leu-OH hydrate
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Amino Acid Derivatives
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Neurological Disease
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Boc-D-Leucine monohydrate (Boc-D-Leu-OH hydrate) is an N-Boc-protected form of D-Leucine. D-Leucine is an unnatural isomer of L-Leucine that acts as an auto-inhibitor of lactic streptococci. D-Leucine shows potent anti-seizure effect .
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- HY-W101889
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N-Boc-N'-xanthyl-L-glutamine
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Amino Acid Derivatives
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Others
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Boc-Gln(Xan)-OH (N-Boc-N'-xanthyl-L-glutamine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antigenic activity .
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- HY-W091365
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N-Boc-N'-xanthyl-L-asparagine
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Amino Acid Derivatives
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Others
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Boc-Asn(Xan)-OH (N-Boc-N'-xanthyl-L-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize locust fat growth hormone .
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- HY-W003605
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N-Boc-D-pyroglutamic acid ethyl ester
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Biochemical Assay Reagents
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Others
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Boc-D-Pyr-Oet (N-Boc-D-pyroglutamic acid ethyl ester) is used as a biochemical assay reagent .
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- HY-168276
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PROTAC Linkers
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Cancer
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Boc-Nonanol is a PROTAC linker. Boc-Nonanol can be used in the synthesis of PROTAC TRIB2 degrader-1 (HY-168274) .
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- HY-W010835
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Boc-S-trityl-D-cysteine
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Amino Acid Derivatives
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Others
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Boc-D-Cys(Trt)-OH (Boc-S-trityl-D-cysteine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize the bicyclic depsipeptide histone deacetylase inhibitor spirocysteine .
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- HY-W008633
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- HY-W011321
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- HY-41631
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(S)-Ethyl-N-Boc-pyroglutamate
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Amino Acid Derivatives
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Others
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Boc-Pyr-Oet is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds .
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- HY-P4548
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Boc-RVRR-AMC
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Furin
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Others
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Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
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- HY-W007529
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PROTAC Linkers
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Cancer
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Boc-6-aminohexanoic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-79096S
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- HY-W014692
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N-t-Boc-amino-D-alanine; Boc-D-Dap-OH
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Amino Acid Derivatives
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Others
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Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity .
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- HY-P4458
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Ser/Thr Protease
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Cancer
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Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
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- HY-Y0978S
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- HY-W009229
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- HY-35028
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Amino Acid Derivatives
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Others
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Boc-Glu-Ofm is a peptide. Boc-Glu-Ofm has been used for the synthesis of ester insulin and cyclic peptide mixtures .
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- HY-P4455
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Bacterial
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Infection
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Boc-AAG-pNA is a glycine endopeptidase substrate. Boc-AAG-pNA can be used to test the amidase activity glycine endopeptidase .
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- HY-W014097
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- HY-W088100
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N-Boc-N'-trityl-D-asparagine; Boc-D-Asn(Trt)-OH
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Amino Acid Derivatives
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Cancer
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Boc-N-gamma-trityl-D-asparagin (N-Boc-N'-trityl-D-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize metastasis-inhibiting or tumor growth-inhibiting metastasis-inhibiting MS derivatives .
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- HY-W101891
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- HY-75970
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N-Boc-Propargylamine
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Biochemical Assay Reagents
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Others
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N-Boc-Propargylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Boc-Propargylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W141812
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- HY-W012000
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Boc-N-Me-Ile-OH
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Amino Acid Derivatives
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Others
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Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a peptide products and can be used as a precursor in organic synthesis and pharmaceuticals .
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- HY-W013253
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PROTAC Linkers
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Cancer
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Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432 (HY-130602) .
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- HY-W089233
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N-Boc-D-glutaMic acid 1-tert-butyl ester
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Amino Acid Derivatives
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Others
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Boc-D-Glu-OtBu (N-Boc-D-glutaMic acid 1-tert-butyl ester) is an amino acid derivative with a Boc protecting group, which can be used to synthesize Adamant-1-yl tripeptide with immunostimulatory activity .
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- HY-34738
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3-(Boc-amino)-1-propanol
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Amino Acid Derivatives
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Others
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Boc-β-Ala-ol (3-(Boc-amino)-1-propanol) is an alanine derivative with a Boc protecting group at the N-terminus, which can be used to synthesize bioactive peptide mimics, such as Nα-Benzoyl-α-azaornithine phenyl ester, which has trypsin inhibitory activity .
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- HY-W013293R
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Amino Acid Derivatives
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Others
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Boc-D-Tyr-OH (Standard) is the analytical standard of Boc-D-Tyr-OH. This product is intended for research and analytical applications. Boc-D-Tyr-OH is a tyrosine derivative .
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- HY-13229
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BOC-D-FMK
Maximum Cited Publications
6 Publications Verification
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Caspase
Apoptosis
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Cancer
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Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor. Boc-D-FMK inhibits apoptosis stimulated by TNF-α with an IC50 of 39 µM.
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- HY-W007618
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Biochemical Assay Reagents
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Others
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Boc-Lys-OH is a lysine derivative of azocyclic and anthraquinone. Boc-Lys-OH is a polypeptide-based heterofunctional linking molecule, which can be used as a biomarker reagent .
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- HY-W048829
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Amino Acid Derivatives
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Others
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Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .
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- HY-W007993
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N-Boc-cycloleucine
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Biochemical Assay Reagents
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Others
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Boc-Cycloleucine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W562116
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Amino Acid Derivatives
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Others
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Boc-Lys(ivdde)-OH is a derivative of amino acid. Boc-Lys(ivdde)-OH can be used for synthesis of lysine containing peptide .
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- HY-169351
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Proteasome
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Cancer
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Boc 3 Arg is the tert-butyl carbamate-protected arginine. Boc 3 Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S proteasome .
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- HY-W002300
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- HY-W008113
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- HY-P10448
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- HY-23122
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- HY-32688
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- HY-42065
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- HY-W017788
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- HY-W018741
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- HY-W002173
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- HY-W041867
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- HY-W052529
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- HY-W012437
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- HY-W012446
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- HY-W007354
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- HY-W019676
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- HY-W007875
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- HY-41121S4
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- HY-W010946
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- HY-W011092
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Nα-Boc-Nδ-Cbz-L-ornithine
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Biochemical Assay Reagents
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Others
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Boc-Orn(Z)-OH (Nα-Boc-Nδ-Cbz-L-ornithine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-65039
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ADC Linker
PROTAC Linkers
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Cancer
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Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-I0781
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ADC Linker
PROTAC Linkers
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Cancer
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Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
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- HY-78931G
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ADC Linker
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Cancer
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Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
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- HY-151652
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ADC Linker
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Others
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Boc-L-Cys(Propargyl)-OH is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH can be used for the research of various biochemical .
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- HY-140098
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ADC Linker
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Cancer
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Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-147052
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PROTAC Linkers
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Cancer
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Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker . Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-41912
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N-[(1,1-Dimethylethoxy)carbonyl]-L-norleucine; Boc-L-norleucine; Boc-norleucine; N-(tert-Butoxycarbonyl)norleucine
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Amino Acid Derivatives
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Others
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Boc-Nle-OH is a leucine derivative .
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- HY-41121S
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- HY-108379
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ADC Linker
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Cancer
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Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W089230
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N,N'-Di-tert-butoxycarbonyl-L-histidine
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Amino Acid Derivatives
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Others
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Boc-His(Boc)-OH (N,N'-Di-tert-butoxycarbonyl-L-histidine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize the dodecapeptide α-mating factor of Saccharomyces cerevisiae .
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- HY-W011167
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- HY-W041864
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- HY-Z0438
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- HY-41257
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- HY-I0931
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- HY-W009673
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N-Boc-L-pyroglutamic acid
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Biochemical Assay Reagents
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Others
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Boc-Pyr-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W015230
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- HY-W011913
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- HY-W041862
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- HY-W050782
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- HY-W013473
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Boc-D-Pipecolic acid
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Biochemical Assay Reagents
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Others
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Boc-D-HoPro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W009258
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- HY-W015231
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- HY-W141779
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- HY-W010788
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- HY-79877
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- HY-W005144
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- HY-W007399
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- HY-W039449
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- HY-W041857
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- HY-W008800
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- HY-W008389
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- HY-W008382
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- HY-W011064
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- HY-W011199
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- HY-W011606
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- HY-W011977
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- HY-W011201
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- HY-W013293
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- HY-W002326
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- HY-I0377
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- HY-W018650
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- HY-W141815
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- HY-W009412
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- HY-W008022
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- HY-W108137
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- HY-151684
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ADC Linker
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Others
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Boc-Ser(O-propargyl)-OH is a click chemistry reagent containing an alkynes group. Boc-Ser(O-propargyl)-OH can be used for the research of various biochemical .
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- HY-P4453
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Caspase
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Cancer
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Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
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- HY-134432A
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Ser/Thr Protease
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Others
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Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2 .
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- HY-134432B
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Ser/Thr Protease
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Others
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Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .
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- HY-60265
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- HY-20797
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- HY-103473
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- HY-W927376
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Fluorescent Dye
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Others
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Boc-Val-Arg-AMC is a synthetic peptide compound. As a specific fluorescent substrate, Boc-Val-Arg-AMC can be specifically cleaved by specific enzymes, especially thrombin, to release a fluorescent molecule AMC (7-amino-4-methylcoumarin), which can be used to monitor thrombin activity. Boc-Val-Arg-AMC can be used to detect thrombin activity in plasma samples .
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- HY-W006937
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Boc-p-amino-D-Phe(Fmoc)-OH; Boc-D-phe(4-NH-fmoc)-OH
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Amino Acid Derivatives
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Others
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Boc-D-(4-fmoc)-aminophenylalanine (Boc-p-amino-D-Phe(Fmoc)-OH) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with gonadotropin-releasing hormone antagonist activity .
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- HY-W013097
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Amino Acid Derivatives
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Others
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Boc-Arg(di-Z)-OH can be used for the synthesis of amino acid. Boc-Arg(di-Z)-OH can be used for the research of inhibitors for processing proteinases. Boc-Arg(di-Z)-OH is coupled via the mixed anhydride (MA) with HGlu(OBzl)-Lys(Z)-Arg(Z,Z)-CH2Cl .
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- HY-139661
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PROTAC Linkers
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Cancer
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Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61 . Boc-bipiperidine-ethynylbenzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W142111
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- HY-40013
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1-Boc-Piperidine-4-carboxylic acid
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Biochemical Assay Reagents
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Others
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Boc-Inp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-151652A
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ADC Linker
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Others
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Boc-L-Cys(Propargyl)-OH (DCHA) is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH (DCHA) can be used for the research of various biochemical .
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- HY-W109513
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Amino Acid Derivatives
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Inflammation/Immunology
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Boc-Lys(Z)-OH (DCHA) is a involves in synthesis thymosin β4, βg and β6 fragments, and increases E-rosette forming capacity in Lupus Nephritis model. Boc-Lys(Z)-OH (DCHA) involves in synthesis Boc-Lyz-OCH3 and acts as a reagent of peptidyl thrombin inhibitors production .
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- HY-159622
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PROTAC Linkers
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Cancer
|
|
Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl is a PROTAC Linker. Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl can be used in synthesis PROTAC GSPT1 degrader-2 (HY-159610) .
|
-
- HY-W034599
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C14-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-W045598
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C16-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs
|
-
- HY-W040417
-
|
|
PI3K
|
Others
|
|
Boc-L-cyclobutylglycine is a glycine derivative that can be used for PI3K inhibitor synthesis .
|
-
- HY-151767
-
|
|
ADC Linker
|
Others
|
|
Boc-Cystamine-Poc (compound H4) is a click chemistry reagent with cystamine building block .
|
-
- HY-169376
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-piperazine-C13-OTs is a PROTAC linker. Boc-piperazine-C13-OTs can be used to synthesize NC-R17 (HY-155075) .
|
-
- HY-W004110
-
-
- HY-W010783
-
-
- HY-W004098
-
-
- HY-W650842
-
|
|
Caspase
|
Cancer
|
|
Boc-Asp(OBzl)-CMK is an inhibitor for IL-1 converting enzyme (ICE, caspase1). Boc-Asp(OBzl)-CMK prevents death of CHP100 neuroblastoma cell, and IL-1β release elicited by the viral coat protein .
|
-
- HY-138379
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007729
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-L-Alaninol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40114
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-79096
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-L-phenylalanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-I0773
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-L-homophenylalanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W011832
-
-
- HY-W013968
-
-
- HY-W018717
-
-
- HY-W013906
-
-
- HY-W009260
-
-
- HY-W018366
-
-
- HY-W004083
-
-
- HY-W062304
-
-
- HY-W013048
-
-
- HY-W013300
-
-
- HY-W013210
-
-
- HY-W014048
-
-
- HY-W009534
-
-
- HY-W004697
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC .
|
-
- HY-W019623
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(Boc-aminooxy)acetic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008185
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-D-alaninol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W014099
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.
|
-
- HY-W039756
-
|
NSC 334362
|
Amino Acid Derivatives
|
Others
|
|
Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent .
|
-
- HY-RS01567
-
|
|
Small Interfering RNA (siRNA)
|
Others
|
|
BOC Human Pre-designed siRNA Set A contains three designed siRNAs for BOC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
BOC Human Pre-designed siRNA Set A
BOC Human Pre-designed siRNA Set A
- HY-W009403
-
-
- HY-W040067
-
-
- HY-W008486
-
-
- HY-W041866
-
-
- HY-W011178
-
-
- HY-W013874
-
-
- HY-78843
-
-
- HY-W009402
-
-
- HY-160795
-
|
|
ADC Linker
|
Cancer
|
|
Boc-NMeVal-Val-Dil-Dap is a linker, that can be used for ADC synthesis.
|
-
- HY-40118
-
|
Boc-L-proline methyl ester
|
Liposome
|
Others
|
|
Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
-
- HY-W038702
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141141
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140421
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-131091
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-Glu(OBzl)-OSu can be used for the solid-phase peptide synthesis containing glutamate benzyl ester residues.
|
-
- HY-P4312
-
-
- HY-140412
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140469
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140413
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminoxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140174
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140173
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138373
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG5-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138468
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG25-benzyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138492
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PPG2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-Y0978S3
-
-
- HY-W008325
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-L-Dap-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W904851
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Piperidine-piperazine-Cbz is a PROTAC linker that can be used in the synthesis of ZLC491 (HY-168162) .
|
-
- HY-159619
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-azetidine-2C-oxotetrahydropyrimidin-bromophenyl is a PROTAC Linker. Boc-azetidine-2C-oxotetrahydropyrimidin-bromophenyl can be used in the synthesis of PROTAC GSPT1 degrader-1 (HY-159609) .
|
-
- HY-168039
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-Piperidine-C5-OH is a PROTAC linker. Boc-NH-Piperidine-C5-OH can be used in the synthesis of PROTAC PIN1 degrader-1 (HY-168037) .
|
-
- HY-W011033
-
-
- HY-155466
-
|
|
Dopamine Receptor
|
Neurological Disease
|
|
Boc-MIF-1-Am (compound 2) is a human dopamine D2 receptor enhancer (EC50=17.82 nM) and is a bioconjugate of melanostatin (MIF-1) and amantadine. Boc-MIF-1-Am (200 μM) exhibited mild neurotoxicity in SH-SY5Y cells .
|
-
- HY-P4319
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin .
|
-
- HY-P4323
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
-
- HY-P4323A
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
-
- HY-140342
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136547
-
|
|
ADC Linker
|
Others
|
|
Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs) .
|
-
- HY-W002900
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-D-Nip-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W013249
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-piperazine-benzoic acid is a PROTAC linker and can be used in the synthesis of PROTACs, such as PROTAC androgen receptor (AR) degrader ARD-2128 (HY-13229) .
|
-
- HY-140049
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140052
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140053
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140050
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminooxy-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140878
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140884
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG9-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG9-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140885
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG12-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140881
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140882
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG7-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG7-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140883
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG8-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140880
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133500
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-HyNic-PEG2-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-HyNic-PEG2-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133502
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-HyNic-PEG2-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-HyNic-PEG2-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138159
-
-
- HY-W016018
-
-
- HY-103473A
-
|
Boc-Met-Leu-Phe-OH TFA
|
Formyl Peptide Receptor (FPR)
|
Inflammation/Immunology
|
|
Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations .
|
-
- HY-103348
-
|
Boc-Asp(OMe)-FMK
|
Caspase
|
Inflammation/Immunology
|
|
Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8 .
|
-
- HY-140116
-
|
|
ADC Linker
|
Cancer
|
|
Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140117
-
|
|
ADC Linker
|
Cancer
|
|
Boc-aminooxy-ethyl-SS-propanol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141142
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130932
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130961
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-137784
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Val-Pro-Arg-AMC hydrochloride is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .
|
-
- HY-P4326
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Val-Pro-Arg-MCA is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .
|
-
- HY-151684A
-
|
|
ADC Linker
|
Others
|
|
Boc-Ser(O-propargyl)-OH (DCHA) is a click chemistry reagent containing a propynyl group.
|
-
- HY-140081
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W011561
-
|
|
ADC Linker
|
Cancer
|
|
Boc-NH-C6-Br is a non-cleavable linker used for antibody-drug conjugates (ADC) .
|
-
- HY-140428
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140435
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140468
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140390
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140423
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminoxy-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140391
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140377
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140233
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140231
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140376
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141304
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140172
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140439
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG3-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141118
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141120
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007322
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133499
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-HyNic-PEG1-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134709
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134744
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Pyrrolidine-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138398
-
|
|
PROTAC Linkers
|
Cancer
|
|
BOC-NH-PEG2-propene is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138441
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138481
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-methyl propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141119
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135947
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190963
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG7-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-129353
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Phe-(Alloc)Lys-PAB-PNP is a used as a cleavable linker for antibody-drug conjugates (ADC).
|
-
- HY-133044
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Pip-alkyne-Ph-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-Pip-alkyne-Ph-COOH can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 effectively induces degradation of androgen receptor (AR) protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM . Boc-Pip-alkyne-Ph-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-P4419
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
-
- HY-W007803
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138311
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG-Thiol (MW 10000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140879
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-N-Amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-78931
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
|
-
- HY-151676
-
|
N-Boc-O-(2-azidoethyl)-L-tyrosine
|
ADC Linker
|
Others
|
|
Boc-L-Tyr(2-azidoethyl)-OH (N-Boc-O-(2-azidoethyl)-L-tyrosine) is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W017970
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-C2-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W008432
-
-
- HY-W013824
-
-
- HY-140725
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG-amine (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140726
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG-amine (MW 3400) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140727
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-79404A
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-beta-t-butyl-d-alanine is an intermediate, can be used in the synthesis of peptides and other amino acids .
|
-
- HY-130975
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Dil-Dap-Phe-OMe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P3318
-
-
- HY-42640
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136037
-
|
|
ADC Linker
|
Cancer
|
|
Boc-amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-135962
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Aminooxy-PEG2-bromide is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136041
-
|
|
ADC Linker
|
Cancer
|
|
Boc-amino-PEG3-SSPy is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-42364
-
-
- HY-Y0029
-
-
- HY-113951
-
|
Boc-Pro-prolinal; (Boc)-Prolyl-prolinal
|
Prolyl Endopeptidase (PREP)
|
Neurological Disease
|
|
Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) is a potent prolyl endopeptidase (PEP; PE) inhibitor, with a Ki value of 15 nM. Prolyl Endopeptidase Inhibitor 1 has anti-amnesic effect .
|
-
- HY-140392
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-Amido-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133436
-
|
|
ADC Linker
|
Cancer
|
|
Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-aminooxy-amide-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-136274
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Boc-A 410099.1 amide-alkylC4-amine is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-alkylC4 linker with terminal amine. Boc-A 410099.1 amide-alkylC4-amine can conjugates with target protein ligands.
|
-
- HY-140430
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-Aminooxy-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140432
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-Aminooxy-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140433
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-Aminooxy-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140838
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140839
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140836
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140840
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG9-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140837
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133356
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG15-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG15-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140236
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG23-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140234
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140232
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140235
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG15-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140438
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133355
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG12-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133405
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-169966
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-CH2-O-(CH2)4-OTs is a PROTAC linker. Boc-CH2-O-(CH2)4-OTs can be used to synthesize PROTAC AR Degrader-5 (HY-160547) .
|
-
- HY-151703
-
|
|
ADC Linker
|
Others
|
|
Boc-D-Lys(N3)-OH is a Boc-protected amino acid derivative, can be used as a click chemistry reagent and an intermediate for synthesis of linkers . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-141122
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133388
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138397
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG15-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138402
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG15-C1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138410
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG11-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130956
-
|
|
ADC Linker
|
Cancer
|
|
Boc-NMe-Val-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-P1449
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-140478
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-amido-PEG4-C3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-168223
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Piperazine-2-F-Ph-CHO (Compound 2) is a PROTAC linker, used for the synthesis of YD54 (HY-168221) .
|
-
- HY-140835
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-N-Amido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-41121S2
-
-
- HY-Y0978
-
-
- HY-161496
-
-
- HY-161499
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NHCH2-Ph-pyrimidine-NH2 is the linker for PROTAC molecule XYD198 (HY-161498) .
|
-
- HY-133501
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-HyNic-PEG2-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-HyNic-PEG2-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-33366
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-126381
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W005056
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140426
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG2-C2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140477
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140415
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140476
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141116
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134737
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG1-C5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138406
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG8-C2-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138475
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG2-ethoxyethane-PEG2-benzyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-168218
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Piperazine-piperidine-2-F-Ph-CHO is a PROTAC linker that can be used in the synthesis of YDR1 (HY-168215) .
|
-
- HY-P1449A
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-141117
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-15400
-
-
- HY-W004896
-
|
PROTAC Linker 11
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG2 (PROTAC Linker 11) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W017772
-
|
PROTAC Linker 10
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3 (PROTAC Linker 10) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W025896
-
|
PROTAC Linker 12
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4 (PROTAC Linker 12) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-41121S1
-
-
- HY-W040244
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-20841
-
|
(S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-4-Pyranoyl-Gly-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-(2S)-Gly-4-pyranoyl ((S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid) is an amino-terminally protected glycine derivative that can be used to synthesize dipeptidyl peptidase IV with antidiabetic activity .
|
-
- HY-W040132
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC . Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC) .
|
-
- HY-140425
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG1-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140427
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138399
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG22-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138432
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG26-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130637
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC Linker which is used for the EED-targeted PROTAC .
|
-
- HY-140237
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Gly-amido-C-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130618
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the Alkyl/ether composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-140834
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-Amido-PEG2-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-N-Amido-PEG2-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W101495S
-
-
- HY-151763
-
|
|
ADC Linker
|
Others
|
|
Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151846
-
|
|
ADC Linker
|
Others
|
|
Boc-L-Pra-OH (DCHA) is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-W022232
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG5-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-W025812
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG2-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-140416
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140473
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG20-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140474
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG24-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140475
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG36-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140470
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140472
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140471
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG10-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138474
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG1-PPG2-C2-azido is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-PEG1-PPG2-C2-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132119
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NHCH2CH2-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NHCH2CH2-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W008352
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-NH-PEG4-CH2CH2NH2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138485
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG1-PPG2-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-160247
-
|
|
Drug-Linker Conjugates for ADC
|
Others
|
|
Boc-Lys-PEG8-N-bis(D-glucose) (compound 89-5) is a drug linker that can be used in the synthesis of antibody-drug conjugates (ADCs) extracted from patent WO2023280227A2 .
|
-
- HY-41650
-
|
(S)-2-((tert-Butoxycarbonyl)amino)-N-methoxy-N-methylpropanamide; (S)-2-(tert-Butoxycarbonylamino)-N-methoxy-N-methylpropionamide
|
Amino Acid Derivatives
|
Others
|
|
Boc-Ala-NMe(OMe) is an alanine derivative .
|
-
- HY-130619
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PROTAC linker, which refers to the PEG composition. Boc-C1-PEG3-C4-OBn can be used in the synthesis of a series of PROTACs, such as PROTAC SGK3 degrader-1 (HY-125878). PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-135930
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG10-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135933
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126677
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-agent-conjugation (ADC). Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA also is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-125888
-
|
PROTAC Linker 32
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-C6-amido-C4-acid (PROTAC Linker 32) is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-151722
-
|
|
ADC Linker
|
Cancer
|
|
Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W250992
-
|
|
ADC Linker
|
Others
|
|
Boc-L-Lys(N3)-OH CHA is a click chemistry reagent containing an azide . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151784
-
|
|
ADC Linker
|
Others
|
|
Boc-D-Aza-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-130897
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG11-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG11-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130899
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG23-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG23-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151824
-
|
|
ADC Linker
|
Others
|
|
Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W008474
-
|
PROTAC Linker 13
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG2-C2-NH2 (PROTAC Linker 13) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-120775
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs .
|
-
- HY-168075
-
|
|
PROTAC Linkers
|
Others
|
|
Boc-PIP-Me-CH2-2,7-diazaspiro[3.5]nonane is the linker of PROTAC K-Ras Degrader-3 (HY-168054), which can be used in the synthesis of PROTACs .
|
-
![Boc-PIP-Me-CH2-2,7-diazaspiro[3.5]nonane](//file.medchemexpress.eu/product_pic/hy-168075.gif)
- HY-108371
-
|
PROTAC Linker 1
|
PROTAC Linkers
|
Cancer
|
|
Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W419403
-
|
|
ADC Linker
|
Others
|
|
Boc-D-Aza-OH (CHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151718
-
|
|
ADC Linker
|
Others
|
|
Boc-L-Tyr(PEG(3)-N3)-OH is a click chemistry agent containing azide. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-125887
-
|
PROTAC Linker 30
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-151718A
-
|
|
ADC Linker
|
Others
|
|
Boc-L-Tyr(PEG(3)-N3)-OH DCHA is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151858
-
|
|
ADC Linker
|
Others
|
|
Boc-L-Lys(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-79046
-
|
Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-; Butyric acid, 2-(carboxyamino)-, N-tert-butyl ester, L- (8CI); (2S)-2-(tert-Butoxycarbonylamino)butanoic acid; (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid
|
Amino Acid Derivatives
|
Others
|
|
Boc-L-2-aminobutanoic acid is an alanine derivative .
|
-
- HY-108372
-
|
PROTAC Linker 2
|
PROTAC Linkers
|
Cancer
|
|
Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.
|
-
- HY-161653
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-C3-O-Ph(NO2)-methylester-O-pyrrolidine-2,5-dione is a linker of PROTAC BRD4 Degrader-26 (HY-161650), and can be used for synthesis of PROTACs .
|
-
- HY-151703A
-
|
|
ADC Linker
|
Others
|
|
Boc-D-Lys(N3)-OH CHA is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-Y0978S2
-
|
N-tert-Butoxycarbonyl-2-aminoacetic acid-2-13C; NSC 127669-2-13C
|
Isotope-Labeled Compounds
Androgen Receptor
|
Endocrinology
|
|
Boc-Glycine-2- 13C is a 13C-labeled Linuron. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive a
|
-
- HY-W047799
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Phe(4-CONH2)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a small-sized HTLV-I protease inhibitor with hydrophilicity .
|
-
- HY-Z0615
-
|
Boc-L-Asp(OBn)-OH
|
Amino Acid Derivatives
|
Others
|
|
(2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid is an aspartic acid derivative .
|
-
![(2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid](//file.medchemexpress.eu/product_pic/hy-z0615.gif)
- HY-W003605A
-
|
|
Amino Acid Derivatives
|
Others
|
|
1-Boc-DL-Pyroglutamic acid ethyl ester is a Boc-protected Pyroglutamic acid derivative, can be used for the synthesis of agents or other compounds .
|
-
- HY-400312
-
-
- HY-P2147
-
|
|
Renin
|
Others
|
|
Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-Ome is a specific renin inhibitor .
|
-
- HY-140419
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-123109
-
|
VH032-Boc
|
Ligands for E3 Ligase
|
Cancer
|
|
(S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology .
|
-
- HY-148549
-
|
|
Others
|
Others
|
|
MC-PEG2-Boc (compound 3b) is a Boc-protected Maleimide. MC-PEG2-Boc can be used for the preparation of maleimide linker .
|
-
- HY-W101935
-
|
N-Boc-D-arginine hydrochloride
|
Amino Acid Derivatives
|
Others
|
|
N-Boc-D-Arg hydrochloride (N-Boc-D-arginine hydrochloride) is an amino acid derivative with a Boc protecting group, which can be used to synthesize desmopressin with the effects of improving nocturia, urinary incontinence and enuresis .
|
-
- HY-140336
-
|
|
PROTAC Linkers
|
Cancer
|
|
C-NH-Boc-C-Bis-(C-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-123109A
-
|
(S,S,S)-VH032-Boc
|
Others
|
Cancer
|
|
(S,S,S)-AHPC-Boc is the isomer of (S,R,S)-AHPC-Boc (HY-123109), and can be used as an experimental control. (S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology .
|
-
- HY-41062
-
-
- HY-160124
-
|
|
FGFR
|
Cancer
|
|
Infigratinib-Boc is a derivative of Infigratinib containing a Boc (t-Butyloxy carbonyl) group. Infigratinib is an ATP-competitive pan-FGFR inhibitor .
|
-
- HY-W019939
-
|
|
ADC Linker
|
Cancer
|
|
Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024) . Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011) .
|
-
- HY-140562
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140565
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140563
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140567
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG4)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-40021
-
|
N-Boc-2-Piperidone
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-2-piperidone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40091
-
|
1-Boc-3-aminopyrrolidine
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-3-Aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-140568
-
|
N-(Hydroxy-PEG3)-N-Boc-PEG4-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
N-(Hydroxy-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140566
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Azido-PEG4-N-Boc-N-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-161931
-
-
- HY-W019799
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG8-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141395
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W584534
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
VH032-CH2-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-CH2-Boc will remove the protecting group under acidic conditions and be directly used in PROTAC molecule synthesis. VH032-CH2-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand.
|
-
- HY-W584535
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
VH032-C3-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C3-Boc will remove the protective group under acidic conditions and be directly used for PROTAC molecular synthesis. VH032-C3-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands.
|
-
- HY-131159
-
-
- HY-130375
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG8-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130380
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG7-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130384
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG6-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140027
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140028
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140029
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG10-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140030
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG14-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG14-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130597
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138733
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG13-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140026
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130662
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG8-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-D1586
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 Boc-hydrazide (chloride) is a cyanine5-labeled and Boc-protected hydrazide fluorescent dye.
|
-
- HY-65039A
-
|
|
Others
|
Cancer
|
|
rel-Boc-Hyp-OMe is the isomer of Boc-Hyp-OMe (HY-65039), and can be used as an experimental control. Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140259
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG4)-NH-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130513
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-125534
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130523
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130534
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130831
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130832
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130833
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130834
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141396
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141400
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG12-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141401
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG13-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140194
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140196
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140195
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141369
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141202
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140385
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140365
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141203
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133212
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135169
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130469
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133211
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140748
-
|
|
PROTAC Linkers
|
Cancer
|
|
BnO-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140749
-
|
|
PROTAC Linkers
|
Cancer
|
|
BnO-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140193
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141368
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141367
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141366
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141389
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141282
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140936
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140965
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140387
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140198
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG20-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140200
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG36-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140966
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141204
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141206
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG11-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141207
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG20-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141281
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140197
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141205
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140199
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134677
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134707
-
|
|
PROTAC Linkers
|
Cancer
|
|
CHO-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138326
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG18-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138340
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138345
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG11-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138346
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138347
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138352
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138368
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138478
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138480
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138449
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096145
-
|
|
PROTAC Linkers
|
Cancer
|
|
Chloro-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134752
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134755
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138722
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140051
-
|
t-Boc-aminooxy-PEG3-Propargyl
|
ADC Linker
|
Cancer
|
|
N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC .
|
-
- HY-W718754
-
-
- HY-133162
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138504
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-164041
-
|
|
PKC
|
Others
|
|
Staurosporine-Boc, a natural product isolated from the actinomyces Streptomyces staurosporeus, is a potent non-selective inhibitor of protein kinase. Staurosporine-Boc inhibits a variety of protein kinases, including protein kinase C (PKC), tyrosine kinase, and serine/threonine kinase. Because of its broad inhibition profile, Staurosporine-Boc is widely used as a tool compound in biological research, especially when studying cell signaling pathways .
|
-
- HY-130404
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140075
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG6-Boc is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-40020
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-3-piperidone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001639
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-3-Oxopiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-46398
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Val-Phe-Boc is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Val-Phe-Boc can be used in the synthesis of the Deruxtecan .
|
-
- HY-40145
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-3-iodoazetidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40029
-
|
(S)-(+)-3-Amino-1-Boc-piperidine
|
Biochemical Assay Reagents
|
Others
|
|
(S)-1-Boc-3-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-130486
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W044078
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-diethanolamine is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-diethanolamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140074
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG4-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-141210
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-41063
-
|
|
ADC Linker
|
Cancer
|
|
N-Boc-N-methyl-D-Valinol is an ADC linker with BOC protecting group.
|
-
- HY-41064
-
|
|
ADC Linker
|
Cancer
|
|
N-Boc-N-methyl-D-Valaldehyde is an ADC linker with a BOC protecting group.
|
-
- HY-W047788
-
|
|
Amino Acid Derivatives
|
Others
|
|
H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities .
|
-
- HY-140781
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140775
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140780
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG9-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140777
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140795
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140778
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140782
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG12-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140784
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140785
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG36-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG36-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133319
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG24-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138457
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG20-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG20-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W005561
-
|
|
Amino Acid Derivatives
|
Others
|
|
H-Dab(Boc)-OMe hydrochloride is an N-terminally protected diaminobutyric acid containing two protecting groups: methoxy (OMe) and tert-butyloxycarbonyl (Boc). H-Dab(Boc)-OMe hydrochloride can be used to synthesize the bifunctional chelator H3Dpaa that can rapidly complex 68Ga under physiological conditions .
|
-
- HY-164637
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Aniline-PEG3-C1-Boc (compound D-1) is an intermediate of cytotoxic drug linker polymer. Aniline-PEG3-C1-Boc can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140628
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140967
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-Amido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140629
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141347
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141346
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141348
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140626
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141345
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140257
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140258
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140444
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cbz-aminooxy-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140627
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140600
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-Bis-(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138447
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-NH-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130742
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-161961
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-NH-C10-Boc (compound S20) is a conjugate of the E3 ubiquitinase ligand Thalidomide and PROTAC Linker, which can recruit Cereblon ubiquitinase. Thalidomide-NH-C10-Boc can couple the target protein ligand through the PTOTAC Linker to synthesize PROTAC molecules with degradation effects. For example, Thalidomide-NH-C10-Boc can couple with the ligand EP300/CBP ligand 2 (HY-161960) to produce the PROTAC molecule dCE-2 (HY-161958) .
|
-
- HY-141361
-
|
|
PROTAC Linkers
|
Cancer
|
|
(2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W090299
-
-
- HY-42488
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196) . Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-W039178
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191). Hydroxy-PEG4-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-W067061
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196) . Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-161576
-
-
- HY-41919
-
|
mDPR(Boc); (S)-MALEOYL-DPR(Boc)-OH·DCHA
|
ADC Linker
|
Cancer
|
|
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W426106
-
|
|
ADC Linker
|
Cancer
|
|
Gly-NH-CH2-Boc is a cleavable ADC linker that can be used to synthesize antibody-conjugated active molecules (ADC) .
|
-
- HY-21629
-
-
- HY-W021597
-
|
|
Others
|
Others
|
|
N-Boc-5-bromoindole is formed as an intermediate for the synthesis of di-Boc-protected 5-aminoindole via a Buchwald-Hartwig amination with tBu-carbamate followed by regioselective bromination .
|
-
- HY-140123
-
|
|
ADC Linker
|
Cancer
|
|
THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-78926
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-2-(S)-pyrrolidinemethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40007
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-4-(aminomethyl)piperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-60218
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-3-(hydroxymethyl)pyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002169
-
-
- HY-W127828
-
|
T-Boc-AC-NTA
|
Biochemical Assay Reagents
|
Others
|
|
t-Boc-aminocaproicnitrilotriacetic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-140031
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-OCH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-44063
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-NH-PEG3-NH-Boc is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-NH-PEG3-NH-Boc acts as a ligand for Cereblon to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-PEG3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-PEG3-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
|
-
- HY-40022
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(R)-1-Boc-3-Hydroxypiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40023
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-1-Boc-3-hydroxypiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40040
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-1-Boc-3-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40097
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(R)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-112516
-
|
|
Others
|
Others
|
|
Fmoc-Lys(amino aldehyde)-Boc is a lysine derivative, and is very sensitive to acid and heat. Fmoc-Lys(amino aldehyde)-Boc and can be used in solid phase synthesis .
|
-
- HY-40098
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-79128
-
-
- HY-140107
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azidoethyl-SS-PEG2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138320
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-N-amido-PEG36-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-164271
-
|
|
Topoisomerase
|
Cancer
|
|
10-Boc-SN-38 is a tert-butyloxycarbonyl (Boc)-protected form of SN-38 (HY-13704). SN-38 is the active metabolite of Irinotecan (HY-16562) .
|
-
- HY-78927
-
|
|
Amino Acid Derivatives
|
Others
|
|
N-Boc-L-Prolinal is a proline with a Boc protecting group, which can be used to synthesize biologically active peptide mimetics, such as the synthesis of Dolastatin 10 (HY-15580) analogs with anti-colon cancer activity .
|
-
- HY-159680
-
|
|
PROTAC Linkers
|
Cancer
|
|
OMs-PEG2-NHAlloc-PEG2-Boc is a PROTAC linker. OMs-PEG2-NHAlloc-PEG2-Boc can be used in synthesis PROTAC SMARCA2/4-degrader-28 (HY-162835) .
|
-
- HY-W141985
-
-
- HY-W025807
-
-
- HY-W005295
-
-
- HY-65000
-
-
- HY-140293
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-42617
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130172
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG2-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130738
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG3-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-145367
-
|
|
ADC Linker
|
Cancer
|
|
Ala-CO-amide-C4-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W584513
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
Thalidomide-NH-(CH2)2-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)2-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)2-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
|
-
- HY-141014
-
-
- HY-130483
-
|
|
PROTAC Linkers
|
Cancer
|
|
Br-PEG3-C2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-130158
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130526
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130532
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133069
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133070
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133071
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-42620
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140383
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140401
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140402
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141365
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140479
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141208
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141209
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140481
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140482
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141364
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141388
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141370
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141371
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141372
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141211
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140480
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140964
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140483
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140403
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140631
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140630
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133336
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG12-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133337
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG24-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133338
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG36-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133335
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG10-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-42619
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138316
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG10-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138349
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-79128S
-
-
- HY-130470
-
|
|
PROTAC Linkers
|
Cancer
|
|
Chloroacetamido-PEG4-C2-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130599
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG2-CH2-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130758
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-PEG1-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-42618
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130520
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-130536
-
|
|
PROTAC Linkers
|
Cancer
|
|
Br-PEG4-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-130330
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W109214
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-L-Dap(Boc,Me)-OH is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of diaminopropionic acid containing peptide .
|
-
- HY-148773
-
|
|
ADC Linker
|
Cancer
|
|
MC-Gly-Gly-Phe-Boc is involved in the synthesis of antibody-drug conjugates (ADCs) to Trastuzumab (HY-P9907). MC-Gly-Gly-Phe-Boc can participate in cancer research .
|
-
- HY-W008034
-
|
|
Amino Acid Derivatives
|
Cancer
|
|
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .
|
-
- HY-168277
-
-
- HY-140779
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-C2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130389
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG4-O-C1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140599
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-S-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140612
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W018464
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-serinol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140991
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W584515
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
Thalidomide-NH-(CH2)3-NH-Boc is a Boc-modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)3-NH-Boc is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules targeting 11β-substituted estradiol.
|
-
- HY-W584520
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
|
-
- HY-40102
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-1-Boc-2-(aminomethyl)pyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40041
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(R)-1-Boc-3-methyl-piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-140163
-
|
|
PROTAC Linkers
|
Cancer
|
|
N,N'-DME-N-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141252
-
|
|
PROTAC Linkers
|
Cancer
|
|
N,N-Diethanol amine-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-59260
-
-
- HY-30090
-
-
- HY-42149
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W005308
-
|
|
Amino Acid Derivatives
|
Cancer
|
|
N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity .
|
-
- HY-130315
-
-
- HY-23167
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR .
|
-
- HY-P2355
-
-
- HY-141006
-
|
|
PROTAC Linkers
|
Cancer
|
|
3,4-Dibromo-Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141007
-
|
|
PROTAC Linkers
|
Cancer
|
|
3,4-Dibromo-Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140776
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-C2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140793
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG2-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140796
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-163232
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Phthalimidinoglutarimide-piperidine-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Phthalimidinoglutarimide-piperidine-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-66024
-
-
- HY-W008359
-
-
- HY-W043473
-
-
- HY-W591438
-
-
- HY-W055870
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG1-(CH2)2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141390
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG9-ethylcarbamoyl-C4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141391
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG9-ethylcarbamoyl-C8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141392
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG9-ethylcarbamoyl-C12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130491
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-NH-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140609
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-Sulfone-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W001484
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-nortropinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002899
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-Boc-nipecotic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-132856
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC .
|
-
- HY-140792
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W584529
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
VH032-C2-NH-Boc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C2-NH-Boc will remove the protecting group under acidic conditions, and can be directly used for the synthesis of PROTAC molecules. VH032-C2-NH-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands.
|
-
- HY-W584530
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
VH032-C4-NH-Boc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL to recruit von Hippel-Lindau (VHL) proteins. VH032-C4-NH-Boc will remove the protecting group under acidic conditions and be directly used in PROTAC molecule synthesis. VH032-C4-NH-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand.
|
-
- HY-W584531
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
VH032-C6-NH-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C6-NH-Boc will remove the protecting group under acidic conditions and be directly used in PROTAC molecule synthesis. VH032-C6-NH-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand.
|
-
- HY-W584533
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
VH032-PEG2-NH-BOC is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-PEG2-NH-BOC will remove the protecting group under acidic conditions and be directly used for PROTAC molecule synthesis. VH032-PEG2-NH-BOC is a key intermediate in the synthesis of PROTAC based on VHL ligand.
|
-
- HY-140256
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(PEG2-C2-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140252
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140750
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyloxy carbonyl-PEG3-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-40014
-
|
1-Boc-Piperidine-3-carboxylic acid
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-piperidine-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-130549
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR .
|
-
- HY-130293
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-134982
-
-
- HY-40181
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-homopiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W004649
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
|
-
- HY-40002
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Boc-Aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-131250
-
-
- HY-140596
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-S-PEG3-Boc is a PEG- and Alkyl/ether -based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-135918
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135938
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135943
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG8-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135804
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W073709
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG1-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-42427
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141327
-
|
Thiol-PEG3-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140156
-
|
Methylamino-PEG4-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140155
-
|
Methylamino-PEG2-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140616
-
|
DNP-PEG6-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140154
-
|
Methylamino-PEG1-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141328
-
|
Thiol-PEG4-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-168019
-
-
- HY-W040113
-
|
|
Others
|
Others
|
|
6-(N-Boc)caproic acid NHS is a protein cross-linking agent.
|
-
- HY-120702
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130503
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG1-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG1-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130505
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG7-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W006445
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG2-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W046471
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG4-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W071583
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG9-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG9-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W071584
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG6-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130100
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG3-C1-Boc is an ADC linker, which belongs to a polyethylene glycol (PEG) linker.
|
-
- HY-W019205
-
-
- HY-W546498
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-Biotinylethylenediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W013734
-
-
- HY-153370
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG3-oxyamine-Boc hydrochloride is an ADC linker . DBCO-PEG3-oxyamine-Boc (hydrochloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130202
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-amido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140604
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140786
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-amido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130690
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG1-SS-PEG1-C2-Boc is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG1-SS-PEG1-C2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-40142
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-N-Boc-3-hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs
|
-
- HY-40115
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-D-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-141250
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-Amino-bis(PEG1-C2-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W021482
-
-
- HY-W129448
-
-
- HY-W004064
-
-
- HY-140032
-
|
Alkyne-ethyl-PEG1-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Alkyne-ethyl-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-ethyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130881
-
|
|
PROTAC Linkers
|
Cancer
|
|
HS-PEG6-CH2CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138355
-
|
|
PROTAC Linkers
|
Cancer
|
|
CHO-CH2-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-40141
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
|
-
- HY-W584532
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
VH032-O-C2-NH-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-O-C2-NH-Boc will remove the protecting group under acidic conditions and can be directly used in PROTAC molecule synthesis. VH032-O-C2-NH-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand.
|
-
- HY-33046
-
|
(2R,3R)-Boc-dolaproine
|
Others
|
Cancer
|
|
N-Boc-dolaproine (Dap) is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .
|
-
- HY-78924
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-D-prolinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010856
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-Orn(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008206
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(±)-Boc-α-phosphonoglycine trimethyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-78931C
-
|
|
Others
|
Cancer
|
|
(S,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
|
-
- HY-78931E
-
|
|
Others
|
Cancer
|
|
(R,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
|
-
- HY-78931F
-
|
|
Others
|
Cancer
|
|
(R,S,S,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
|
-
- HY-W061614
-
|
|
Amino Acid Derivatives
|
Others
|
|
(4R)-1-Boc-4-fluoro-D-proline is an amino acid derivative that can be used for preparation of peptidomimetics, dihydropyridopyrimidines and pyridopyrimidines .
|
-
- HY-W037441
-
-
- HY-140292
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG9-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG9-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140291
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140289
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG1-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140290
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG2-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-131189
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
N-Boc-SBP-0636457-OH, a ligand for E3 ubiquitin ligase, is used in the recruitment of IAP E3 ligases. N-Boc-SBP-0636457-OH can be connected to the ligand for Bcl-xL by a linker to form PROTAC Bcl-xL degrader-1 (HY-131188).
|
-
- HY-138651
-
|
|
ADC Linker
|
Inflammation/Immunology
|
|
PAB-Val-Lys-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) for stimulating an immune response .
|
-
- HY-134853
-
|
|
Others
|
Cancer
|
|
2-(Boc-amino)ethanethiol (compound 35) is a bifunctional cross-linker that can be used in the synthesis of bifunctional azobenzene glycoconjugates .
|
-
- HY-W000923
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(4-Boc-aminophenyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-140576
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG2-C2-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141251
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Hydroxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140253
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Amino-PEG3)-N-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140255
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Amino-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140254
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140446
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141288
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Biotin-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140393
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Tos-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-23641
-
|
|
ADC Linker
|
Cancer
|
|
NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
|
-
- HY-79129
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-132088
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-69348
-
|
|
Biochemical Assay Reagents
|
Others
|
|
S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-126884
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-78931A
-
|
|
Others
|
Cancer
|
|
(R,S,S,R,S)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
|
-
- HY-78931B
-
|
|
Others
|
Cancer
|
|
(S,S,S,S,R)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
|
-
- HY-32959
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-2-pyrroleboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40028
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-3-Boc-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001478
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-4-Bromopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-75026
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-4-hydroxypiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-140157
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Me-N-bis(PEG4-C2-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W008296
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC .
|
-
- HY-126670
-
|
|
ADC Linker
|
Cancer
|
|
mDPR(Boc)-Val-Cit-PAB is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC) .
|
-
- HY-139353
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Phe-Lys(Boc)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131959
-
-
- HY-170315
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ethyne-C2-Pip-CO-Pip-Boc (Compound 21) is a PROTAC linker. Ethyne-C2-Pip-CO-Pip-Boc can be used to synthesize QA-68 (HY-150797) .
|
-
- HY-130712
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-C2-amido-C2-Boc is a PROTAC linker, which refers to the alkyl/ether composition. NH2-C5-NH-Boc can be used in the synthesis of a series of PROTACs, such as the PROTAC CDK2/9 Degrader-1 (HY-130709) .
|
-
- HY-140595
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-S-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-43721
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277 (HY-130122) . N-Boc-4-pentyne-1-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-163960
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-Ph-NH-cyclohexane-NH-Boc is a PROTAC linker. NH2-Ph-NH-cyclohexane-NH-Boc can be used in synthesis PROTAC erf3a Degrader-1 (HY-163938) .
|
-
- HY-W000438
-
|
|
Amino Acid Derivatives
|
Cancer
|
|
N-Boc-O-tosyl hydroxylamine is used as a safe and efficient nitrogen source for the N-amination of aryl and alkyl amines .
|
-
- HY-W008279
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG2-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-135798
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141194
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG16-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141195
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141196
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG36-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141197
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG23-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141192
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141191
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141193
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130193
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140223
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140224
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG8-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141200
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141081
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141201
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-aminooxy-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140935
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141279
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140414
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141280
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG24-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134738
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetamide-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138493
-
|
|
PROTAC Linkers
|
Cancer
|
|
F-PEG2-S-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138500
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG12-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138520
-
|
|
PROTAC Linkers
|
Cancer
|
|
5-[Boc(methyl)amino]pentanal is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
![5-[Boc(methyl)amino]pentanal](//file.medchemexpress.eu/product_pic/hy-138520.gif)
- HY-144076
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-amido-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190945
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190857
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130770
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG3-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of SGK3 kinase PROTAC degrader .
|
-
- HY-40151
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Methyl 1-Boc-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Boc-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1
|
-
- HY-161201
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-piperazine-pyrimidine-piperazine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperazine-pyrimidine-piperazine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161205
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-PIP-(R)C-pyrrolidine-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-PIP-(R)C-pyrrolidine-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161208
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Deoxy-thalidomide-Pip-C-PIP-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Deoxy-thalidomide-Pip-C-PIP-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161210
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-azetidine-C-PIP-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-azetidine-C-PIP-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-W010922
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists .
|
-
- HY-W042478
-
-
- HY-W090421
-
-
- HY-42489
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG3-CH2CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-40152
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]
|
-
- HY-159572
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-C5-Azacyclohexane-N-Boc is a PROTAC linker. NH2-C5-Azacyclohexane-N-Boc can be used in synthesis XD2-149 (HY-159570) .
|
-
- HY-159571
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-NH-C5-azacyclohexane-N-Boc is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-NH-C5-azacyclohexane-N-Boc can be used to synthesize XD2-149 (HY-159570) .
|
-
- HY-140992
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-C4-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007655
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-D-Lys(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003985
-
-
- HY-168231
-
|
|
PROTAC Linkers
|
Cancer
|
|
trans-Boc-Piperidine-C-PIP-O-cyclobutane-OH is a PROTAC linker. trans-Boc-Piperidine-C-PIP-O-cyclobutane-OH can be used to synthesize PROTAC SMARCA2 degrader-27 (HY-168229) .
|
-
- HY-130449
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130422
-
|
Tos-PEG4-Boc
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM .
|
-
- HY-140868
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG3-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140867
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140869
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140054
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-aminooxy-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-aminooxy-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-131184
-
|
|
PROTAC Linkers
|
Inflammation/Immunology
|
|
N-Boc-piperazine-C3-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-N-piperazine-C3-COOH can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183) .
|
-
- HY-30105
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183) .
|
-
- HY-129968
-
|
|
PROTAC Linkers
|
Cancer
|
|
AM-Imidazole-PA-Boc is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC IRAK4 degrader-1 (HY-129966) .
|
-
- HY-43304
-
|
|
Others
|
Cancer
|
|
N-Boc-dolaproine-methyl is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .
|
-
- HY-140934
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG2-NH-Boc is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W001294
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(R)-(-)-Boc-3-pyrrolidinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W000913
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-(Boc-amino)benzeneboronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W019032
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .
|
-
- HY-W067489
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG1-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-168040
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-O-C5-piperidine-NH-Boc is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-O-C5-piperidine-NH-Boc can be used to synthesize PROTAC PIN1 degrader-1 (HY-168037) .
|
-
- HY-33046A
-
|
(2R,3R)-Boc-dolaproine dicyclohexylamine
|
Others
|
Cancer
|
|
N-Boc-dolaproine dicyclohexylamine is an amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity. And contains dicyclohexylamine .
|
-
- HY-W739800
-
-
- HY-114430
-
|
|
ADC Linker
|
Others
|
|
Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-130638
-
|
VH032-O-Ph-PEG1-NH-Boc
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is a synthesized E3 ligase ligand-linker conjugate which is used for the EED-targeted PROTAC .
|
-
- HY-133310
-
|
HO-PEG7-CH2COOtBu
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133311
-
|
HO-PEG8-CH2COOtBu
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG8-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133312
-
|
HO-PEG10-CH2COOtBu
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG10-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133313
-
|
HO-PEG12-CH2COOtBu
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG12-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133314
-
|
HO-PEG24-CH2COOtBu
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG24-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-117079
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG2-OH) is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W002886
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-cis-4-hydroxy-L-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
|
-
- HY-152502
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5-N-Boc-aminomethyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-79295
-
|
N-Boc-3-Fluoro-D-phenylalanine; N-tert-Butoxycarbonyl-3-fluoro-D-phenylalanine
|
Amino Acid Derivatives
|
Others
|
|
N-BOC-3-Fluoro-D-phenylalanine is a phenylalanine derivative .
|
-
- HY-136269
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
A 410099.1, amine-Boc hydrochloride is a functionalized IAP ligand and can be used for the synthesis of PROTACs, such as PROTACs targeting BTK (PROTACs 4 and 5) .
|
-
- HY-79691
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-3-(Boc-amino)pyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-161185
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
Thalidomide-piperidine-O-azetidine-boc is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.
|
-
- HY-W002887
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-Hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the Synthesis of ADCs or PROTACs.
|
-
- HY-153151
-
|
|
Others
|
Cancer
|
|
Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .
|
-
- HY-140077
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG3-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140553
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130976
-
|
|
ADC Linker
|
Cancer
|
|
N-Boc-Val-Dil-Dap-Doe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141291
-
|
|
PROTAC Linkers
|
Cancer
|
|
N'-Boc-N-(Gly-Oleoyl)-Lys is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-Y0755
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-cis-4-hydroxy-L-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
|
-
- HY-161193
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-piperazine-(R)-C-pyrrolidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperazine-(R)-C-pyrrolidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161195
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Deoxy-thalidomide-piperidine-C-piperazine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Deoxy-thalidomide-piperidine-C-piperazine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161198
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-azetidine-pyrrolidine-C-piperidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-azetidine-pyrrolidine-C-piperidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161206
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-Pip-C-Pip-O-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-Pip-C-Pip-O-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-40249
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W056267
-
|
|
PROTAC Linkers
|
Cancer
|
|
3-Boc-3-azaspiro[5.5]undecane-9-carbaldehyde is a PROTAC linker, and can be used for synthesis of PROTAC SOS1 degrader-8 (HY-161634) .
|
-
![3-Boc-3-azaspiro[5.5]undecane-9-carbaldehyde](//file.medchemexpress.eu/product_pic/hy-w056267.gif)
- HY-130527
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140636
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140539
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140540
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140380
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-aminoxy-Boc-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140538
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140972
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG9-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140378
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG8-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140418
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140437
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG7-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140429
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140424
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140436
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG7-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140417
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140422
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132089
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134681
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143821
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143825
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W003499
-
-
- HY-136273
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-PEG3 linker with terminal amine. A 410099.1 amide-PEG2-amine-Boc can conjugates with target protein ligands.
|
-
- HY-136272
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
A 410099.1 amide-PEG3-amine-Boc is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-PEG3 linker with terminal amine. A 410099.1 amide-PEG3-amine-Boc can conjugates with target protein ligands.
|
-
- HY-140816
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140817
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140794
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-C-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140849
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-Ala-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Ala-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138377
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG8-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138388
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-formylhydrazine-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-formylhydrazine-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138464
-
|
|
PROTAC Linkers
|
Cancer
|
|
Br-Boc-C2-azido is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Br-Boc-C2-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-P2389
-
-
- HY-P2408
-
-
- HY-P2388
-
-
- HY-P2412
-
-
- HY-W090446
-
|
|
PROTAC Linkers
|
Cancer
|
|
4-Boc-amino-22-dimethylbutyric acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-131190
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
N-Boc-SBP-0636457-OH is a synthesized E3 ligase ligand-linker conjugate that incorporates IAP ligand and a linker. N-Boc-SBP-0636457-OH can be used to design a PROTAC Bcl-xL degrader-1 (HY-131188) .
|
-
- HY-161656
-
|
|
PROTAC Linkers
|
Cancer
|
|
PIP-C-3-Azaspiro[5.5]undecane-boc is the linker for PROTAC. PIP-C-3-Azaspiro[5.5]undecane-boc is utilized for synthesis of PROTAC SOS1 degrader-10 (HY-161654) .
|
-
![PIP-C-3-Azaspiro[5.5]undecane-boc](//file.medchemexpress.eu/product_pic/hy-161656.gif)
- HY-140089
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W008024
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release .
|
-
- HY-140588
-
|
N-Benzyl-N-bis(PEG3-t-butyl ester)
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-N-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-42912
-
|
|
Others
|
Cancer
|
|
N-Boc-dolaproine-OH ((+)-phenylethylamine) is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .
|
-
- HY-42912A
-
|
|
Others
|
Cancer
|
|
N-Boc-dolaproine-OH dicyclohexylamine is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .
|
-
- HY-128801
-
|
PROTAC Linker 5
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-133461
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG6-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133462
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-168227
-
|
|
PROTAC Linkers
|
Cancer
|
|
trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc is a PROTAC linker. trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc can be used in the synthesis of PROTAC SMARCA2/4-degrader-35 (HY-168225) .
|
-
- HY-131168
-
|
VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH (VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) is a E3 ligase ligand-linker conjugate that contains on one end a VHL ligand. (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is used in PROTAC technology .
|
-
- HY-136154
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-145488
-
|
|
ADC Linker
|
Cancer
|
|
MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W190966
-
|
|
PROTAC Linkers
|
Others
|
|
t-Boc-Aminooxy-PEG4-t-butyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-151841
-
|
|
ADC Linker
|
Others
|
|
N3-L-Lys(Boc)-OH is a click chemistry reagent containing an azide group . N3-L-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140294
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-C2-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C2-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140295
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-C3-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C3-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W003233
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Boc-pyrazole-4-boronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W320685
-
|
|
Drug Intermediate
|
Others
|
|
(S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.
|
-
- HY-140434
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140431
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-Aminooxy-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151654
-
|
|
ADC Linker
|
Others
|
|
N3-D-Lys(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151729
-
|
|
ADC Linker
|
Others
|
|
N3-D-Dab(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Dab(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151735
-
|
|
ADC Linker
|
Others
|
|
N3-L-Dab(Boc)-OH is a click chemistry reagent containing an azide group. N3-L-Dab(Boc)-OH can be used for the research of various biochemical . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151764
-
|
|
ADC Linker
|
Others
|
|
N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-140510
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Methyl-N-(t-Boc)-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096165
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-N-amido-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143828
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-N-amido-PEG10-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143829
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-N-amido-PEG15-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140201
-
|
17-(Amino-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG6-amido-C16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140202
-
|
17-(Amino-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG9-amido-C16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W046355
-
-
- HY-169377
-
-
- HY-132163
-
|
|
ADC Linker
|
Cancer
|
|
MP-PEG4-VK(Boc)G-OSu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-161203
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-azetidine-piperazine-C2-O-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-azetidine-piperazine-C2-O-C-boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-W007056
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .
|
-
- HY-40178
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-C4-NH-Boc (compound 15) is a PROTAC linker, which refers to the Alkyl/ether composition. NH2-C4-NH-Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-141199
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-C2-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140534
-
|
|
PROTAC Linkers
|
Cancer
|
|
4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140222
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG2-C2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140405
-
|
|
PROTAC Linkers
|
Cancer
|
|
1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W046071
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-trans-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-49053
-
|
|
Others
|
Cancer
|
|
N-Boc-dolaproine-amide-Me-Phe is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .
|
-
- HY-41061
-
|
|
Apoptosis
|
Cancer
|
|
D-Boc Valine methyl ester is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis .
|
-
- HY-W106325
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-N-Me-D-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize somatostatin-dopamine chimeric analogs .
|
-
- HY-140558
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140557
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG3-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151764A
-
|
|
ADC Linker
|
Others
|
|
N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-132004
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-O-C4-NH-Boc is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs, such as BSJ-03-204 (HY-136250) .
|
-
- HY-140406
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130941
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-N-bis-PEG3-NH-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P2355A
-
-
- HY-140575
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140574
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140788
-
|
5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG9-amido-C4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140790
-
|
13-(Azide-PEG9-ethylcarbamoyl)tridecanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG9-amido-C12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C12-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140789
-
|
9-(Azide-PEG9-ethylcarbamoyl)nonanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG9-amido-C8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140787
-
|
17-(Azide-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG6-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140791
-
|
17-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133572
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130639
-
-
- HY-141005
-
|
|
PROTAC Linkers
|
Cancer
|
|
3,4-Dibromo-Mal-PEG2-N-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140556
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(PEG4-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140555
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-159974
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Me-SJ46411-PEG1-Piperazine-Boc is a conjugate of E3 ubiquitin ligase and PROTAC linker, which can be used for the synthesis of PROTAC molecules. For example, Me-SJ46411-PEG1-Piperazine-Boc combined with target protein ligand (+)-JQ-1 (HY-13030) can be used to synthesize the selective BRD3 PROTAC degrader SJ46420 (HY-168635). .
|
-
- HY-161186
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-piperidine-C-azetidine-C2-O-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperidine-C-azetidine-C2-O-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-134592
-
-
- HY-151736
-
|
|
ADC Linker
|
Others
|
|
N3-L-Dap(Boc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-L-Dap(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-40226
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Amino-1-Boc-piperidine-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W674127
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Biotinyl-N'-Boc-1,6-hexanediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-162668
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Biotinyl-N'-Boc-1,4-butanediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-140260
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(PEG3-C2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130531
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(C2-PEG2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140536
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG3)-N-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W017829
-
|
|
PROTAC Linkers
|
Cancer
|
|
1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140537
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140261
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(PEG4-C2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W003222
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-tert-Boc-cis-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-161194
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-acetyl-azetidine-PIP-boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S,R,S)-AHPC-acetyl-azetidine-PIP-boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-130312
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140569
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(PEG1-OH)-N-Boc-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140090
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140093
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-161187
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-piperidine-1,6-diazaspiro[3.3]heptane-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperidine-1,6-diazaspiro[3.3]heptane-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
![Thalidomide-piperidine-1,6-diazaspiro[3.3]heptane-boc](//file.medchemexpress.eu/product_pic/hy-161187.gif)
- HY-33241
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-hexahydro-1H-azepine-4-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-161207
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-acetyl-Pip-O-azetidine-boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S,R,S)-AHPC-acetyl-Pip-O-azetidine-boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-145177
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader . (From patent WO2017180417A1 compound s7).
|
-
- HY-128803
-
|
PROTAC Linker 7
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-128805
-
|
PROTAC Linker 9
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG3-NH-Boc (PROTAC Linker 9) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-163219
-
-
- HY-130669
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-amido-C2-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141254
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132973
-
|
|
ADC Linker
|
Cancer
|
|
MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-143830
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-N-amido-PEG2-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-161792
-
|
|
PROTAC Linkers
|
Infection
|
|
N3-C5-O-C-Boc is a linker, which can be utilized for the synthesis of PROTAC SARS-CoV-2 Mpro degrader-3 (HY-161789) .
|
-
- HY-140524
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140525
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140526
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-136934
-
|
[Boc-Glu(Obzl)]2-Lys-Ome
|
P-glycoprotein
|
Cancer
|
|
Reversin 205 ([Boc-Glu(Obzl)]2-Lys-Ome) is a P-glycoprotein (ABCB1) inhibitor. Reversin 205 is a peptide chemosensitizer .
|
-
- HY-154111
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
8-(N-Boc-aminomethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-140094
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-161209
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-2,6-diazaspiro[3.4]octane-C-Pip-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-2,6-diazaspiro[3.4]octane-C-Pip-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
![Thalidomide-2,6-diazaspiro[3.4]octane-C-Pip-boc](//file.medchemexpress.eu/product_pic/hy-161209.gif)
- HY-163225
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161204
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-O-C4H4-N(Me)-piperidine-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-O-C4H4-N(Me)-piperidine-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-163216
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
PROTAC PTK6 ligand-O-4,4-dimethylpiperidine-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. PROTAC PTK6 ligand-O-4,4-dimethylpiperidine-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-133702
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aniline-piperazine-C3-NH-Boc (Compound Int-3) is a PROTAC linker, and can be used for synthesis of Pomalidomide-C3-adavosertib (HY-133618) and AZD1775 (HY-10993) (a Wee1 inhibitor) .
|
-
- HY-140347
-
|
tert-Butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate
|
PROTAC Linkers
|
Cancer
|
|
APN-C3-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . APN-C3-NH-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W101718
-
|
|
Isotope-Labeled Compounds
ADC Linker
|
Cancer
|
|
Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody agent coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1].
|
-
- HY-130598
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs N-(Azido-PEG3)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-79128S1
-
-
- HY-140999
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-Lys(t-Boc)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141259
-
|
|
PROTAC Linkers
|
Cancer
|
|
C-NH-Boc-C-Bis-(C1-PEG1-PFP) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-33292
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(1R,2R)-N-Boc-1,2-cyclohexanediamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-140092
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-161192
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-O-C4H4-N(Me)-piperidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-O-C4H4-N(Me)-piperidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161196
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
![Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C-boc](//file.medchemexpress.eu/product_pic/hy-161196.gif)
- HY-163221
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-140561
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140554
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(C2-PEG1-azide) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(C2-PEG1-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140871
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Boc-PEG3)-N-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140872
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG2)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Boc-PEG2)-N-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140560
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140559
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W002736
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N,N'-Di-Boc-1H-pyrazole-1-carboximidamide (Compound 1) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-140337
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-163215
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S)-PROTAC PTK6 ligand-O-4,4-dimethylpiperidine-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S)-PROTAC PTK6 ligand-O-4,4-dimethylpiperidine-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-163228
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
PROTAC PTK6 ligand-O-C2-O-piperidine-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. PROTAC PTK6 ligand-O-C2-O-piperidine-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-40171
-
|
PROTAC Linker 22
|
PROTAC Linkers
|
Cancer
|
|
NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W004710
-
|
PROTAC Linker 23
|
PROTAC Linkers
|
Cancer
|
|
NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-134679
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-C1-PEG5-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W004640
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-163229
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
(1r,4r)-Thalidomide-piperidine-N(Me)-CH-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1r,4r)-Thalidomide-piperidine-N(Me)-CH-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-169364
-
|
|
PD-1/PD-L1
|
Others
|
|
2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc is the PD-L1 ligand-linker conjugate part of AUTAC PD-L1 degrader-3 (HY-169363). 2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc can be utilized in AUTAC synthesis .
|
-
- HY-130820
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) .
|
-
- HY-140564
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140242
-
|
|
ADC Linker
|
Cancer
|
|
NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a cleavable 28 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131186
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-amido-C3-piperazine-N-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183) .
|
-
- HY-163224
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S)-PROTAC PTK6 ligand-O-C2-O-piperidine-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S)-PROTAC PTK6 ligand-O-C2-O-piperidine-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-143849
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130854
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-NH-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used for MI-389 (compound 22) synthesis. MI-389 is a potent phthalimide PROTAC degrader based on the multi-targeted receptor tyrosine kinase inhibitor sunitinib (HY-10255A) .
|
-
- HY-163222
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
4-Methylanisole-dihydrouracil-imidazo[1,2-a]pyridine-piperidine-NH-Boc is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.
|
-
![4-Methylanisole-dihydrouracil-imidazo[1,2-a]pyridine-piperidine-NH-Boc](//file.medchemexpress.eu/product_pic/hy-163222.gif)
- HY-163217
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
![PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc](//file.medchemexpress.eu/product_pic/hy-163217.gif)
- HY-W699503
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-1,5-imino-D-glucitol is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-163230
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
![(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc](//file.medchemexpress.eu/product_pic/hy-163230.gif)
- HY-159077
-
|
|
PROTAC Linkers
|
Cancer
|
|
H2N-C6-NH-CO-CH2-O-Ph-CH2-NH-Boc is a linker. H2N-C6-NH-CO-CH2-O-Ph-CH2-NH-Boc can be utilized for synthesis of PROTAC BET Degrader-12 (HY-158764) .
|
-
- HY-168076
-
|
|
PROTAC-Linker Conjugates for PAC
|
Cancer
|
|
(S)-Deoxy-thalidomide-2,7-diazaspiro[3.5]nonane-CH2-Me-PIP-Boc consists of E3 ligase ligand and PROTAC linker of PROTAC K-Ras Degrader-3 (HY-168054). (S)-Deoxy-thalidomide-2,7-diazaspiro[3.5]nonane-CH2-Me-PIP-Boc is promising for research of cancers .
|
-
![(S)-Deoxy-thalidomide-2,7-diazaspiro[3.5]nonane-CH2-Me-PIP-Boc](//file.medchemexpress.eu/product_pic/hy-168076.gif)
- HY-141287
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151677
-
|
|
ADC Linker
|
Others
|
|
(2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide . (2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W022240
-
|
PROTAC Linker 17
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-163220
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-CO-CH2-O-CH2-piperidine-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S,R,S)-AHPC-CO-CH2-O-CH2-piperidine-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-163223
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-CO-CH2-piperazine-C3-piperazine-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S,R,S)-AHPC-CO-CH2-piperazine-C3-piperazine-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-42776
-
|
PROTAC Linker 15
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG3-C2-NH-Boc (PROTAC Linker 15) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-161189
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C-boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
![Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C-boc](//file.medchemexpress.eu/product_pic/hy-161189.gif)
- HY-130853
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology .
|
-
- HY-151677A
-
|
|
ADC Linker
|
Others
|
|
(2R,4S)-Boc-D-Pro(4-N3)-OH DCHA is a click chemistry reagent containing an azide . (2R,4S)-Boc-D-Pro(4-N3)-OH (DCHA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151848
-
|
|
ADC Linker
|
Others
|
|
(2R,4R)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-P10117
-
-
- HY-P10061
-
|
|
Cathepsin
|
Cancer
|
|
Cathepsin K inhibitor 4 is a potent carbohydrazide Cathepsin K inhibitor with IC50s of 13 nM, 269 nM, 296 nM for human, rat, mouse Cathepsin K, respectively .
|
-
- HY-P2097
-
-
- HY-P1994
-
-
- HY-161183
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
(S)-Thalidomide-O-(1S,3r)-C4H4-N(Me)-Pip-C2-O-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-O-(1S,3r)-C4H4-N(Me)-Pip-C2-O-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-163226
-
|
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
|
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
![(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc](//file.medchemexpress.eu/product_pic/hy-163226.gif)
- HY-163227
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Ligands for E3 Ligase
Autophagy
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Cancer
|
|
(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
![(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc](//file.medchemexpress.eu/product_pic/hy-163227.gif)
- HY-W048673
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Amino Acid Derivatives
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Others
|
|
Boc-Dap(Boc)-OH is an amino acid derivative with a Boc protecting group and can be used in the synthesis of primary amides .
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-
- HY-125884
-
|
Cereblon Ligand-Linker Conjugates 21; E3 Ligase Ligand-Linker Conjugates 54
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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|
Pomalidomide-amido-C4-amido-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
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-
- HY-125883
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Cereblon Ligand-Linker Conjugates 20; E3 Ligase Ligand-Linker Conjugates 53
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E3 Ligase Ligand-Linker Conjugates
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Cancer
|
|
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
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-
- HY-141399
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|
PROTAC Linkers
|
Cancer
|
|
m-PEG10-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141398
-
|
Methyl-PEG9-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
m-PEG9-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141397
-
|
Methyl-peg8-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
m-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-168196
-
-
- HY-W017882
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|
|
ADC Linker
PROTAC Linkers
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Cancer
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|
Boc-trans-D-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-trans-D-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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-
- HY-168016
-
|
|
PROTACs
YAP
|
Cancer
|
|
PROTAC YAP degrader-1 (compound YZ-6) is a PROTAC targeting YAP and also inhibits the nuclear localization of YAP. PROTAC YAP degrader-1 is composed of PROTAC target protein ligand NSC682769 (HY-168017) (red part) and E3 ubiquitin ligase ligand + Linker conjugate (R,S,R)-AHPC-PEG2-C2-boc (HY-168019) (blue+black part), in which the PROTAC Linker used is Acid-PEG2-C2-Boc (HY-140480) and the target protein ligand activity control is Demethyl-NSC682769 (HY-168018) [1] .
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-
- HY-101064S
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PPAR
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Others
|
|
Fmoc-leucine- 13C is a 13C-labeled Boc-Glycine[1].
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-
- HY-40174A
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Biochemical Assay Reagents
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Others
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|
tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-P3936
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Fluorescent Dye
|
Others
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|
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
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-
- HY-W002680
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ADC Linker
PROTAC Linkers
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Cancer
|
|
N-Boc-cis-4-hydroxy-D-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-D-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1
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-
- HY-169350
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Glutathione S-transferase
|
Cancer
|
|
EA-B2L is a potent degrader of glutathione S-transferase (GSTP), with the DC50 of 48 μM. EA-B2L is a kind of Boc2Lys-linked Ethacrynic acid (HY-B1640). EA-B2L plays an important role in cancer research .
|
-
- HY-136269A
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-
- HY-W002421
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Biochemical Assay Reagents
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Others
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|
tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-50284
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Biochemical Assay Reagents
|
Others
|
|
(1-(tert-Butoxycarbonyl)-1H-indol-2-yl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-76366
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Biochemical Assay Reagents
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Others
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|
(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W000924
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Biochemical Assay Reagents
|
Others
|
|
3-(tert-Butoxycarbonylamino)phenyl-boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
- HY-41049
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|
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ADC Linker
|
Cancer
|
|
NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates .
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-
- HY-133503
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amide-PEG2-oxyamineBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007586
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-1-(tert-Butoxycarbonyl)azetidine-2-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W190962
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|
|
PROTAC Linkers
|
Cancer
|
|
BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007941S
-
-
- HY-W337644
-
|
|
Amino Acid Derivatives
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Others
|
|
Fmoc-L-Homoarg(Et)2-OH hydrochloride is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of homoarginine containing peptide .
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-
- HY-W584525
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Ligands for E3 Ligase
|
Cancer
|
|
VH032-NH-CO-CH2-NHBoc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL to recruit von Hippel-Lindau (VHL) proteins. VH032-NH-CO-CH2-NHBoc will remove the Boc protection under acidic conditions, and connect with the target protein ligand through a linker to form a PROTAC molecule, which is a key intermediate for the synthesis of PROTAC based on VHL ligand.
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-
- HY-W800843
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|
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Liposome
|
Cancer
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|
tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate is an aminolipid featuring a Boc-protected primary amine, a propylamine spacer attached to an octanoate chain and a C11 chain.
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-
- HY-131864
-
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|
EGFR
PROTACs
|
Cancer
|
|
SJF-1528 is a potent EGFR PROTAC degrader with DC50 values of 39.2 nM and 736.2 nM for wild-type EGFR in OVCAR8 cells and Exon 20 Ins mutated EGFR in HeLa cells. SJF-1528 also degrades HER2 (Pink: ligand for target protein (HY-159047); Black: linker Tos-PEG2-CH2-Boc (HY-130532); Blue: ligand for E3 ligase (S,R,S)-AHPC (HY-125845)) .
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-
- HY-131864A
-
|
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PROTACs
EGFR
|
Cancer
|
|
SJF-1528 hemihydrate is the hemihydrate form of SJF-1528 (HY-131864). SJF-1528 hemihydrate is a EGFR PROTAC degrader with DC50 values of 39.2 nM and 736.2 nM for wild-type EGFR in OVCAR8 cells and Exon 20 Ins mutated EGFR in HeLa cells. SJF-1528 hemihydrate also degrades HER2. (Pink: ligand for target protein (HY-159047); Black: linker Tos-PEG2-CH2-Boc (HY-130532); Blue: ligand for E3 ligase (S,R,S)-AHPC (HY-125845))
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-
- HY-159570
-
|
|
PROTACs
STAT
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Cancer
|
|
XD2-149 is a PROTAC targeting STAT3. XD2-149 consists of PROTAC target protein ligand Napabucasin (HY-13919) (red part), E3 ligase Thalidomide (HY-14658) (black part), and linker NH2-C5-Azacyclohexane-N-Boc (HY-159572) (blue part). The E3 ligase + linker conjugate is Thalidomide-NH-C5-azacyclohexane-N-Boc (HY-159571), and the active control of the target protein ligand is Thalidomide acid (HY-159573) [1] .
|
-
- HY-40146
-
|
N-Boc-3-azetidinone
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl 3-oxoazetidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W800849
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 315 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. One of these esters features a symmetrical branched C17 tail, while the other is an asymmetric C11 tail.
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-
- HY-161960
-
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|
Ligands for Target Protein for PROTAC
Epigenetic Reader Domain
|
Cancer
|
|
EP300/CBP ligand 2 (compound S19) is a ligand targeting the bromodomain of CREB binding protein (CBP) and E1A-associated protein (EP300). EP300/CBP ligand 2 can be used as a target protein ligand in the PROTAC structure, and can be coupled to the E3 ubiquitin ligase ligand through the PTOTAC Linker to synthesize PROTAC molecules with degradation effects. For example, EP300/CBP ligand 2 can be coupled with the conjugate (E3 ubiquitin enzyme ligand + Linker) Thalidomide-NH-C10-Boc (HY-161961) to produce the PROTAC molecule dCE-2 (HY-161958) .
|
-
- HY-161497
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-benzylamine-Py-NH2 is a conjugate of E3 ligase ligand and linker, which is consisted of a Thalidomide (HY-14658) and the Linker Boc-NHCH2-Ph-Py-NH2 (HY-161496). Thalidomide-benzylamine-Py-NH2 is utilized for synthesis of PROTAC molecule XYD190 (HY-161494) .
|
-
- HY-149917
-
|
|
PROTACs
Itk
|
Cancer
|
|
ITK degrader 1 is a highly selective degrader of interleukin-2-inducible T-cell kinase (ITK; DC50=3.6 nM in vivo in mice), with good plasma exposure levels. ITK degrader 1 induces rapid, and prolonged ITK degradation and suppresses IL-2 secretion (EC50=35.2 nM, Jurkat cells) stimulated by anti-CD3 antibodyin vivo. ITK degrader 1 consists of target protein ligand (red part) ITK ligand 1 (HY-168387), PROTAC linker (black part) Piperidine-C2-piperazine-Boc (HY-168388) and E3 ubiquitinase ligand (blue part) Thalidomide 5-fluoride (HY-W087383). E3 ubiquitinase and PROTAC linker can form Thalidomide-piperidine-C2-piperazine-Boc (HY-168389) .
|
-
- HY-161958
-
|
|
PROTACs
Histone Acetyltransferase
|
Cancer
|
|
dCE-2 (compound 5) is a PROTAC targeting CREB binding protein (CBP) and E1A-associated protein (EP300), which was developed based on the crystal structure of bromodomain (BRD) inhibitors. dCE-2 is composed of E3 ubiquitin ligase ligand Thalidomide-4-OH (HY-103596) (blue part), PROTAC Linker tert-Butyl 11-aminoundecanoate (HY-130715) (black part) and PROTAC target protein ligand EP300/CBP ligand 2 (HY-161960) (red part), of which the target protein ligand activity control is EP300/CBP ligand 1 (HY-161959), and the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-NH-C10-Boc (HY-161961) [1] .
|
-
- HY-168217
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-piperazine-piperidine-2-F-Ph-CHO is a E3 ligase ligand-linker conjugate, which is consisted of a Thalidomide (HY-14658) and a linker Boc-Piperazine-piperidine-2-F-Ph-CHO (HY-168218). Thalidomide-piperazine-piperidine-2-F-Ph-CHO is utilized for synthesis of PROTAC molecule YDR1 (HY-168215) .
|
-
- HY-159973
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
Me-SJ46411 is an E3 ubiquitin ligase ligand, which can be used for the synthesis of PROTAC molecules. For example, Me-SJ46411 combined with PROTAC linker Boc-Piperazine-OH (HY-20797) and target protein ligand (+)-JQ-1 (HY-13030) can be used to synthesize the selective BRD3 PROTAC degrader SJ46420 (HY-168635). .
|
-
- HY-161500
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-NHCH2-Ph-pyrimidine-NH2 is a conjugate of E3 ligase ligand and linker, which is consisted of a Thalidomide (HY-14658) and a Linker Boc-NHCH2-Ph-pyrimidine-NH2 (HY-161499). Thalidomide-NHCH2-Ph-pyrimidine-NH2 is utilized for synthesis of PROTAC molecule XYD198 (HY-161498) .
|
-
- HY-W584518
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.
|
-
- HY-161972
-
|
|
PROTACs
Glutathione Peroxidase
Ferroptosis
|
Cancer
|
|
ZX782 is a Hty-type PROTAC targeting GPX4 and a ferroptosis inducer, which induces GPX4 degradation and significantly increases lipid ROS accumulation in HT1080 cells. ZX782 can be used to treat AD by reducing the size and/or number of brain amyloid plaques and by inhibiting the spread of IL-1beta-positive microglial-like cells around amyloid plaques. ZX782 is labeled with hydrophobic benzyl alcohol (HBA) and appears bright blue under acidic conditions, which can be used for quantitative determination . ZX782 is composed of target protein ligand (red part) ML-210 (HY-100003), PROTAC linker (black part) Bromo-PEG2-CH2-Boc (HY-141371) and Hty molecule (blue part) Adamantan-1-ylmethanamine (HY-W037848). The conjugate consisting of Hyt and linker parts is Adamantan-C-amide-PEG2-C-Br (HY-161974), and the activity control of the target protein ligand is Hydroxyl-ML-210 (HY-161973).
|
-
- HY-W584523
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-4-NH-PEG1-COOH TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-COOH TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-COOH TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
|
-
- HY-W584521
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-4-NH-PEG1-NH2 TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-NH2 TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
|
-
- HY-144995
-
|
CDK4/6-IN-11
|
PROTACs
CDK
|
Cancer
|
|
CDK4/6-IN-11 is a potent PROTAC CDK4/6 degrader . CDK4/6-IN-11 consists of a thalidomide-based E3 ligase ligand (blue part) Thalidomide-NH-CH2-COOH (HY-131717), a target protein ligand (red part) Palbociclib (HY-50767), and a PROTAC linker (black part) Boc-NH-C4-Br (HY-W007803). E3 ligase ligand and linker can form Thalidomide-NH-amido-C4-Br (HY-170307).
|
-
- HY-160221
-
|
|
PROTACs
Androgen Receptor
|
Cancer
|
|
PROTAC AR Degrader-7 (compound 99) is a PROTAC targeting androgen receptor with an IC50 value of 3 nM. PROTAC AR Degrader-7 is composed of PROTAC target protein ligand AR ligand-32 (HY-170303) (red part), E3 ligase ligand E3 ligase Ligand 44 (HY-170304) (blue part) and PROTAC Linker N-Boc-piperazine (HY-30105) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is E3 Ligase Ligand-linker Conjugate 145 (HY-170305) .
|
-
- HY-155075
-
|
|
PROTACs
Glutathione Peroxidase
Ferroptosis
|
Cancer
|
|
NC-R17 is a PROTAC-class, non-covalent GPX4 degrader based on RSL3, involved in ferroptosis. NC-R17 has antitumor activity and is used for non-covalent GPX4 PROTAC design . NC-R17 consists of a target protein ligand (red part) Demethyl-RSL3 (HY-135832); an E3 ubiquitin ligase ligand (blue part) Lenalidomide (HY-A0003) and a PROTAC linker (black part) (HY-169376). E3 ubiquitin ligase and linker can form Lenalidomide-C13-piperazine-Boc (HY-169377); the active control for the target protein ligand is RSL3-4-Me (HY-169375).
|
-
- HY-150797
-
|
QA-68-ZU81
|
PROTACs
Epigenetic Reader Domain
|
Inflammation/Immunology
Cancer
|
|
QA-68 (QA-68-ZU81) is an effective PROTAC-class BRD9 degrader. QA-68 can inhibit cell cycle progression and cell colony formation. QA-68 has antiproliferative activity against acute myeloid leukemia (AML) cell lines . QA-68 can be formed by a target protein ligand (red part) EA-89 (HY-170314), an E3 ubiquitin ligase ligand (blue part) Lenalidomide-I (HY-131318), and a PROTAC linker (black part) Ethyne-C2-Pip-CO-Pip-Boc (HY-170315). E3 ubiquitin ligase and linker can form Lenalidomide-ethyne-C2-Pip-CO-Pip (HY-170319); the active control for the target protein ligand is EA-89-Succinic acid (HY-170317).
|
-
- HY-169385
-
|
|
AUTOTACs
Androgen Receptor
|
Cancer
|
|
ATC-324 is an bivalent AR (Androgen Receptor) degrader based on the protein degradation technology platform AUTOphagy-TArgeting Chimera (AUTOTAC). ATC-324 induces the formation of AR/p62 complex, leading to autophagy-lysosomal degradation of AR. ATC-324 can reduce nuclear AR levels and downregulate target gene expression of AR and AR-v7, and also has a degradation effect on common AR mutants in PCa . ATC-324 is composed of target-binding ligand (TBL) Enzalutamide (HY-70002) and p62/SQSTM1 autophagy-targeting ligand (ATL) YT 6-2 analog-1 (HY-169386), connected by Boc-NH-PEG4-CH2CH2NH2 (HY-W008352). Among them, the active control of the target protein ligand is Enzalutamide carboxylic acid (HY-70002B), and the conjugate composed of the autophagy-targeting ligand and the linker is YT 6-2-PEG3-C2-NH2 (HY-169387).
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-134432B
-
|
|
Dyes
|
|
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .
|
-
- HY-138159
-
-
- HY-78931G
-
|
|
Fluorescent Dye
|
|
Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
|
-
- HY-D1586
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5 Boc-hydrazide (chloride) is a cyanine5-labeled and Boc-protected hydrazide fluorescent dye.
|
| Cat. No. |
Product Name |
Type |
-
- HY-W007743
-
|
Boc-L-pipecolic acid
|
Biochemical Assay Reagents
|
|
Boc-Pip-OH (Boc-L-pipecolic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W009229
-
-
- HY-75970
-
|
N-Boc-Propargylamine
|
Biochemical Assay Reagents
|
|
N-Boc-Propargylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Boc-Propargylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W007618
-
|
|
Amino acids and Derivatives
|
|
Boc-Lys-OH is a lysine derivative of azocyclic and anthraquinone. Boc-Lys-OH is a polypeptide-based heterofunctional linking molecule, which can be used as a biomarker reagent .
|
-
- HY-W013473
-
|
Boc-D-Pipecolic acid
|
Biochemical Assay Reagents
|
|
Boc-D-HoPro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W101891
-
-
- HY-W007993
-
|
N-Boc-cycloleucine
|
Biochemical Assay Reagents
|
|
Boc-Cycloleucine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-78931G
-
|
|
Biochemical Assay Reagents
|
|
Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
|
-
- HY-W009673
-
|
N-Boc-L-pyroglutamic acid
|
Biochemical Assay Reagents
|
|
Boc-Pyr-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40013
-
|
1-Boc-Piperidine-4-carboxylic acid
|
Biochemical Assay Reagents
|
|
Boc-Inp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010783
-
-
- HY-W007729
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-Alaninol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40114
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-79096
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-phenylalanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-I0773
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-homophenylalanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W019623
-
|
|
Biochemical Assay Reagents
|
|
(Boc-aminooxy)acetic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008185
-
|
|
Biochemical Assay Reagents
|
|
Boc-D-alaninol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008325
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-Dap-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002900
-
|
|
Biochemical Assay Reagents
|
|
Boc-D-Nip-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40021
-
|
N-Boc-2-Piperidone
|
Biochemical Assay Reagents
|
|
1-Boc-2-piperidone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40091
-
|
1-Boc-3-aminopyrrolidine
|
Biochemical Assay Reagents
|
|
1-Boc-3-Aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40020
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-3-piperidone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001639
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-3-Oxopiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40145
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-3-iodoazetidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40029
-
|
(S)-(+)-3-Amino-1-Boc-piperidine
|
Biochemical Assay Reagents
|
|
(S)-1-Boc-3-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W090299
-
-
- HY-21629
-
|
|
Cell Assay Reagents
|
|
N-Boc-4-piperidinemethanol (compound 4) is an acetylcholinesterase (AChE) inhibitor. N-Boc-4-piperidinemethanol can used ti study Alzheimer’s Disease .
|
-
- HY-78926
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-2-(S)-pyrrolidinemethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40007
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-4-(aminomethyl)piperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-60218
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-3-(hydroxymethyl)pyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127828
-
|
T-Boc-AC-NTA
|
Biochemical Assay Reagents
|
|
t-Boc-aminocaproicnitrilotriacetic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40022
-
|
|
Biochemical Assay Reagents
|
|
(R)-1-Boc-3-Hydroxypiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40023
-
|
|
Biochemical Assay Reagents
|
|
(S)-1-Boc-3-hydroxypiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40040
-
|
|
Biochemical Assay Reagents
|
|
(S)-1-Boc-3-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40097
-
|
|
Biochemical Assay Reagents
|
|
(R)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40098
-
|
|
Biochemical Assay Reagents
|
|
(S)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008034
-
|
|
Drug Delivery
|
|
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .
|
-
- HY-40102
-
|
|
Biochemical Assay Reagents
|
|
(S)-1-Boc-2-(aminomethyl)pyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40041
-
|
|
Biochemical Assay Reagents
|
|
(R)-1-Boc-3-methyl-piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W001484
-
|
|
Biochemical Assay Reagents
|
|
N-Boc-nortropinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002899
-
|
|
Biochemical Assay Reagents
|
|
(S)-Boc-nipecotic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40014
-
|
1-Boc-Piperidine-3-carboxylic acid
|
Biochemical Assay Reagents
|
|
1-Boc-piperidine-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40181
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-homopiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W004649
-
|
|
Chelators
|
|
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
|
-
- HY-40002
-
|
|
Biochemical Assay Reagents
|
|
4-Boc-Aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W546498
-
|
|
Biochemical Assay Reagents
|
|
N-Boc-Biotinylethylenediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-40115
-
|
|
Biochemical Assay Reagents
|
|
Boc-D-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-78924
-
|
|
Biochemical Assay Reagents
|
|
N-Boc-D-prolinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010856
-
|
|
Biochemical Assay Reagents
|
|
Fmoc-Orn(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008206
-
|
|
Biochemical Assay Reagents
|
|
(±)-Boc-α-phosphonoglycine trimethyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W000923
-
|
|
Biochemical Assay Reagents
|
|
(4-Boc-aminophenyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-69348
-
|
|
Biochemical Assay Reagents
|
|
S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-32959
-
|
|
Biochemical Assay Reagents
|
|
N-Boc-2-pyrroleboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-40028
-
|
|
Biochemical Assay Reagents
|
|
(S)-3-Boc-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W001478
-
|
|
Biochemical Assay Reagents
|
|
N-Boc-4-Bromopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W007655
-
|
|
Biochemical Assay Reagents
|
|
Fmoc-D-Lys(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W001294
-
|
|
Biochemical Assay Reagents
|
|
(R)-(-)-Boc-3-pyrrolidinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W000913
-
|
|
Biochemical Assay Reagents
|
|
4-(Boc-amino)benzeneboronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W739800
-
|
|
Drug Delivery
|
|
N-Boc-1-pivaloyl-D-erythro-sphingosine is a kind of biochemical reagent.
|
- HY-79691
-
|
|
Biochemical Assay Reagents
|
|
(S)-3-(Boc-amino)pyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-40249
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W003233
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-pyrazole-4-boronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-40226
-
|
|
Gene Sequencing and Synthesis
|
|
4-Amino-1-Boc-piperidine-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W674127
-
|
|
Biochemical Assay Reagents
|
|
N-Biotinyl-N'-Boc-1,6-hexanediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .
|
- HY-162668
-
|
|
Biochemical Assay Reagents
|
|
N-Biotinyl-N'-Boc-1,4-butanediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .
|
- HY-33241
-
|
|
Biochemical Assay Reagents
|
|
N-Boc-hexahydro-1H-azepine-4-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-33292
-
|
|
Biochemical Assay Reagents
|
|
(1R,2R)-N-Boc-1,2-cyclohexanediamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W002736
-
|
|
Biochemical Assay Reagents
|
|
N,N'-Di-Boc-1H-pyrazole-1-carboximidamide (Compound 1) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
- HY-W699503
-
|
|
Carbohydrates
|
|
N-Boc-1,5-imino-D-glucitol is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
- HY-40174A
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W002421
-
|
|
Biochemical Assay Reagents
|
|
tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-50284
-
|
|
Biochemical Assay Reagents
|
|
(1-(tert-Butoxycarbonyl)-1H-indol-2-yl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-76366
-
|
|
Biochemical Assay Reagents
|
|
(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W000924
-
|
|
Biochemical Assay Reagents
|
|
3-(tert-Butoxycarbonylamino)phenyl-boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W007586
-
|
|
Biochemical Assay Reagents
|
|
(S)-1-(tert-Butoxycarbonyl)azetidine-2-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-40146
-
|
N-Boc-3-azetidinone
|
Biochemical Assay Reagents
|
|
tert-Butyl 3-oxoazetidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2237
-
-
- HY-P1795
-
-
- HY-W753820A
-
|
Boc-Leu-Arg-Arg-AMC TFA
|
Biochemical Assay Reagents
|
Others
|
|
Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
|
-
- HY-115391
-
|
Boc-Leu-Arg-Arg-AMC
|
Biochemical Assay Reagents
|
Others
|
|
Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
|
-
- HY-W013781
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-Glu(OBzl)-OH (Compound 9) is a glutamic acid derivative commonly used in Boc SPPS. Glutamic acid residues increase the hydrophilicity of the polypeptide and play an important structural and receptor binding role .
|
-
- HY-P4716
-
|
|
Peptides
|
Inflammation/Immunology
|
|
Boc-D-Trp(For)-OH, containing the amino acid tryptophan, is synthesized by the ammonolysis of Boc-protected D-alanine, followed by cyclization to form a dipeptide with ninhydrin. Boc-D-Trp(For)-OH has pharmacological properties, including inhibition of growth hormone release, induction of sleep and antiinflammatory .
|
-
- HY-P5834
-
-
- HY-P2669
-
-
- HY-P10059
-
|
|
Peptides
|
Others
|
|
Boc-Val-Gly-Arg-βNA is a colorimetric substrate for plasminogen activator .
|
-
- HY-P10060
-
-
- HY-P2715
-
|
|
Peptides
|
Others
|
|
Boc-Leu-Ser-Thr-Arg-AMC is a fluorogenic AMC-linked protease substrate .
|
-
- HY-P2008
-
|
IEGR-AMC
|
Factor Xa
|
Cardiovascular Disease
|
|
Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .
|
-
- HY-W048332
-
-
- HY-W129194
-
-
- HY-W008919
-
|
N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester
|
Amino Acid Derivatives
|
Others
|
|
Boc-Lys(Boc)-Onp (N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester) is a lysine with a Boc protecting group. Boc-Lys(Boc)-Onp was used as a substrate for a catalyst model to study its enzymatic hydrolysis reaction catalyzed by a copper(II) complex .
|
-
- HY-41121
-
|
Boc-Ala-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein .
|
-
- HY-41912B
-
|
Boc-D-Nle-OH; N-Boc-D-norleucine
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-norleucine (Boc-D-Nle-OH) is a leucine derivative that can be used for peptide synthesis .
|
-
- HY-W801296
-
|
Boc-L-Pyroglutamicacidtert-butylester
|
Peptides
|
Others
|
|
Boc-Pyr-OtBu (Boc-L-Pyroglutamicacidtert-butylester) is a peptide intermediate and can be used in peptide synthesis.
|
-
- HY-W101495
-
|
N-Boc-L-leucine monohydrate
|
Amino Acid Derivatives
|
Others
|
|
Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .
|
-
- HY-W077219
-
|
Boc-Arg(Mtr)-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
|
-
- HY-W002299
-
|
Boc-D-Leu-OH hydrate
|
Amino Acid Derivatives
|
Neurological Disease
|
|
Boc-D-Leucine monohydrate (Boc-D-Leu-OH hydrate) is an N-Boc-protected form of D-Leucine. D-Leucine is an unnatural isomer of L-Leucine that acts as an auto-inhibitor of lactic streptococci. D-Leucine shows potent anti-seizure effect .
|
-
- HY-W101889
-
|
N-Boc-N'-xanthyl-L-glutamine
|
Amino Acid Derivatives
|
Others
|
|
Boc-Gln(Xan)-OH (N-Boc-N'-xanthyl-L-glutamine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antigenic activity .
|
-
- HY-W091365
-
|
N-Boc-N'-xanthyl-L-asparagine
|
Amino Acid Derivatives
|
Others
|
|
Boc-Asn(Xan)-OH (N-Boc-N'-xanthyl-L-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize locust fat growth hormone .
|
-
- HY-W003605
-
|
N-Boc-D-pyroglutamic acid ethyl ester
|
Biochemical Assay Reagents
|
Others
|
|
Boc-D-Pyr-Oet (N-Boc-D-pyroglutamic acid ethyl ester) is used as a biochemical assay reagent .
|
-
- HY-W351592
-
|
Boc-S-acetamidomethyl-L-penicillamine
|
Peptides
|
Others
|
|
Boc-Pen(Acm)-OH (Boc-S-acetamidomethyl-L-penicillamine) is a peptide intermediate and can be used in peptide synthesis.
|
-
- HY-W010835
-
|
Boc-S-trityl-D-cysteine
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-Cys(Trt)-OH (Boc-S-trityl-D-cysteine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize the bicyclic depsipeptide histone deacetylase inhibitor spirocysteine .
|
-
- HY-W008633
-
-
- HY-W011321
-
-
- HY-41631
-
|
(S)-Ethyl-N-Boc-pyroglutamate
|
Amino Acid Derivatives
|
Others
|
|
Boc-Pyr-Oet is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds .
|
-
- HY-P4548
-
|
Boc-RVRR-AMC
|
Furin
|
Others
|
|
Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
|
-
- HY-W014692
-
|
N-t-Boc-amino-D-alanine; Boc-D-Dap-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity .
|
-
- HY-P4458
-
|
|
Ser/Thr Protease
|
Cancer
|
|
Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
|
-
- HY-35028
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-Glu-Ofm is a peptide. Boc-Glu-Ofm has been used for the synthesis of ester insulin and cyclic peptide mixtures .
|
-
- HY-P4455
-
|
|
Bacterial
|
Infection
|
|
Boc-AAG-pNA is a glycine endopeptidase substrate. Boc-AAG-pNA can be used to test the amidase activity glycine endopeptidase .
|
-
- HY-W014097
-
-
- HY-W088100
-
|
N-Boc-N'-trityl-D-asparagine; Boc-D-Asn(Trt)-OH
|
Amino Acid Derivatives
|
Cancer
|
|
Boc-N-gamma-trityl-D-asparagin (N-Boc-N'-trityl-D-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize metastasis-inhibiting or tumor growth-inhibiting metastasis-inhibiting MS derivatives .
|
-
- HY-W141812
-
-
- HY-W012000
-
|
Boc-N-Me-Ile-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a peptide products and can be used as a precursor in organic synthesis and pharmaceuticals .
|
-
- HY-W089233
-
|
N-Boc-D-glutaMic acid 1-tert-butyl ester
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-Glu-OtBu (N-Boc-D-glutaMic acid 1-tert-butyl ester) is an amino acid derivative with a Boc protecting group, which can be used to synthesize Adamant-1-yl tripeptide with immunostimulatory activity .
|
-
- HY-34738
-
|
3-(Boc-amino)-1-propanol
|
Amino Acid Derivatives
|
Others
|
|
Boc-β-Ala-ol (3-(Boc-amino)-1-propanol) is an alanine derivative with a Boc protecting group at the N-terminus, which can be used to synthesize bioactive peptide mimics, such as Nα-Benzoyl-α-azaornithine phenyl ester, which has trypsin inhibitory activity .
|
-
- HY-W013293R
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-Tyr-OH (Standard) is the analytical standard of Boc-D-Tyr-OH. This product is intended for research and analytical applications. Boc-D-Tyr-OH is a tyrosine derivative .
|
-
- HY-W007618
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-Lys-OH is a lysine derivative of azocyclic and anthraquinone. Boc-Lys-OH is a polypeptide-based heterofunctional linking molecule, which can be used as a biomarker reagent .
|
-
- HY-W048829
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .
|
-
- HY-W562116
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-Lys(ivdde)-OH is a derivative of amino acid. Boc-Lys(ivdde)-OH can be used for synthesis of lysine containing peptide .
|
-
- HY-W002300
-
-
- HY-W008113
-
-
- HY-P10448
-
-
- HY-23122
-
-
- HY-32688
-
-
- HY-42065
-
- HY-W017788
-
- HY-W018741
-
- HY-W002173
-
- HY-W041867
-
- HY-W052529
-
- HY-W012437
-
- HY-W012446
-
- HY-W007354
-
- HY-W019676
-
- HY-W007875
-
- HY-W010946
-
- HY-W141845
-
|
|
Peptides
|
Others
|
|
Boc-3-(3-quinolyl)-DL-Ala-OH is a Boc-protected quinolyl Alanine derivative, can be used to synthesis compounds.
|
- HY-41912
-
|
N-[(1,1-Dimethylethoxy)carbonyl]-L-norleucine; Boc-L-norleucine; Boc-norleucine; N-(tert-Butoxycarbonyl)norleucine
|
Amino Acid Derivatives
|
Others
|
|
Boc-Nle-OH is a leucine derivative .
|
- HY-W089230
-
|
N,N'-Di-tert-butoxycarbonyl-L-histidine
|
Amino Acid Derivatives
|
Others
|
|
Boc-His(Boc)-OH (N,N'-Di-tert-butoxycarbonyl-L-histidine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize the dodecapeptide α-mating factor of Saccharomyces cerevisiae .
|
- HY-W011167
-
- HY-W041864
-
- HY-Z0438
-
- HY-41257
-
- HY-I0931
-
- HY-W015230
-
- HY-W011913
-
- HY-W041862
-
- HY-W050782
-
- HY-W009258
-
- HY-W015231
-
- HY-W141779
-
- HY-W010788
-
- HY-79877
-
- HY-W005144
-
- HY-W007399
-
- HY-W039449
-
- HY-W041857
-
- HY-W008800
-
- HY-W008389
-
- HY-W008382
-
- HY-W011064
-
- HY-W011199
-
- HY-W011606
-
- HY-W011977
-
- HY-W011201
-
- HY-W013293
-
- HY-W002326
-
- HY-I0377
-
- HY-W018650
-
- HY-W141815
-
- HY-W009412
-
- HY-W008022
-
- HY-P4706
-
- HY-W011073
-
- HY-P4453
-
|
|
Caspase
|
Cancer
|
|
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
|
- HY-134432B
-
|
|
Ser/Thr Protease
|
Others
|
|
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .
|
- HY-60265
-
- HY-103473
-
- HY-W006937
-
|
Boc-p-amino-D-Phe(Fmoc)-OH; Boc-D-phe(4-NH-fmoc)-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-(4-fmoc)-aminophenylalanine (Boc-p-amino-D-Phe(Fmoc)-OH) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with gonadotropin-releasing hormone antagonist activity .
|
- HY-W013097
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-Arg(di-Z)-OH can be used for the synthesis of amino acid. Boc-Arg(di-Z)-OH can be used for the research of inhibitors for processing proteinases. Boc-Arg(di-Z)-OH is coupled via the mixed anhydride (MA) with HGlu(OBzl)-Lys(Z)-Arg(Z,Z)-CH2Cl .
|
- HY-P4209
-
|
|
Peptides
|
Others
|
|
Boc-GRR-AMC is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity .
|
- HY-W142111
-
- HY-W109513
-
|
|
Amino Acid Derivatives
|
Inflammation/Immunology
|
|
Boc-Lys(Z)-OH (DCHA) is a involves in synthesis thymosin β4, βg and β6 fragments, and increases E-rosette forming capacity in Lupus Nephritis model. Boc-Lys(Z)-OH (DCHA) involves in synthesis Boc-Lyz-OCH3 and acts as a reagent of peptidyl thrombin inhibitors production .
|
- HY-W040417
-
|
|
PI3K
|
Others
|
|
Boc-L-cyclobutylglycine is a glycine derivative that can be used for PI3K inhibitor synthesis .
|
- HY-34611
-
|
N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH
|
Peptides
|
Neurological Disease
Cancer
|
|
Boc-L-2,4-Diaminobutyric acid is a derivative of L-2,4-Diaminobutyric acid (HY-101414) [1.
|
- HY-W004110
-
- HY-W004098
-
- HY-W650842
-
|
|
Caspase
|
Cancer
|
|
Boc-Asp(OBzl)-CMK is an inhibitor for IL-1 converting enzyme (ICE, caspase1). Boc-Asp(OBzl)-CMK prevents death of CHP100 neuroblastoma cell, and IL-1β release elicited by the viral coat protein .
|
- HY-W011832
-
- HY-W013968
-
- HY-W018717
-
- HY-W013906
-
- HY-W009260
-
- HY-W018366
-
- HY-W004083
-
- HY-W062304
-
- HY-W013048
-
- HY-W013300
-
- HY-W013210
-
- HY-W014048
-
- HY-W009534
-
- HY-W141814
-
- HY-P4209A
-
|
|
Peptides
|
Others
|
|
Boc-GRR-AMC (TFA) is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity .
|
- HY-W039756
-
|
NSC 334362
|
Amino Acid Derivatives
|
Others
|
|
Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent .
|
- HY-W009403
-
- HY-W040067
-
- HY-W008486
-
- HY-W041866
-
- HY-W011178
-
- HY-W013874
-
- HY-78843
-
- HY-W009402
-
- HY-40118
-
|
Boc-L-proline methyl ester
|
Liposome
|
Others
|
|
Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
- HY-P4312
-
- HY-W011033
-
- HY-P4319
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin .
|
- HY-P4323
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
- HY-P4323A
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
- HY-W016018
-
- HY-P4326
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Val-Pro-Arg-MCA is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .
|
- HY-P4419
-
|
|
Fluorescent Dye
|
Others
|
|
Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
- HY-W008432
-
- HY-W013824
-
- HY-79404A
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-beta-t-butyl-d-alanine is an intermediate, can be used in the synthesis of peptides and other amino acids .
|
- HY-P3318
-
- HY-42364
-
- HY-Y0029
-
- HY-W142047
-
|
|
Peptides
|
Others
|
|
Boc-(R)-4-[4-(trifluoromethyl)benzyl]-L-proline is a proline derivative .
|
- HY-P1449
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
- HY-Y0978
-
- HY-P4310
-
|
|
Peptides
|
Others
|
|
Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain .
|
- HY-P1449A
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
- HY-15400
-
- HY-20841
-
|
(S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-4-Pyranoyl-Gly-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-(2S)-Gly-4-pyranoyl ((S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid) is an amino-terminally protected glycine derivative that can be used to synthesize dipeptidyl peptidase IV with antidiabetic activity .
|
- HY-P4331
-
|
|
Peptides
|
Others
|
|
Boc-Gln-Gly-Arg-AMC is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4314
-
|
|
Peptides
|
Others
|
|
Boc-Gly-Lys-Arg-AMC is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4332
-
|
|
Peptides
|
Others
|
|
Boc-Glu(OBzl)-Ala-Arg-AMC is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4333
-
|
|
Peptides
|
Others
|
|
Boc-Glu(OBzl)-Gly-Arg-AMC is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-41650
-
|
(S)-2-((tert-Butoxycarbonyl)amino)-N-methoxy-N-methylpropanamide; (S)-2-(tert-Butoxycarbonylamino)-N-methoxy-N-methylpropionamide
|
Amino Acid Derivatives
|
Others
|
|
Boc-Ala-NMe(OMe) is an alanine derivative .
|
- HY-79046
-
|
Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-; Butyric acid, 2-(carboxyamino)-, N-tert-butyl ester, L- (8CI); (2S)-2-(tert-Butoxycarbonylamino)butanoic acid; (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid
|
Amino Acid Derivatives
|
Others
|
|
Boc-L-2-aminobutanoic acid is an alanine derivative .
|
- HY-W047799
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Phe(4-CONH2)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a small-sized HTLV-I protease inhibitor with hydrophilicity .
|
- HY-W051937
-
|
|
Peptides
|
Others
|
|
N-[(1,1-Dimethylethoxy)carbonyl]-1-(triphenylmethyl)-D-histidine is a histidine derivative .
|
- HY-Z0615
-
|
Boc-L-Asp(OBn)-OH
|
Amino Acid Derivatives
|
Others
|
|
(2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid is an aspartic acid derivative .
|
- HY-W003605A
-
|
|
Amino Acid Derivatives
|
Others
|
|
1-Boc-DL-Pyroglutamic acid ethyl ester is a Boc-protected Pyroglutamic acid derivative, can be used for the synthesis of agents or other compounds .
|
- HY-400312
-
- HY-P2147
-
|
|
Renin
|
Others
|
|
Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-Ome is a specific renin inhibitor .
|
- HY-W101935
-
|
N-Boc-D-arginine hydrochloride
|
Amino Acid Derivatives
|
Others
|
|
N-Boc-D-Arg hydrochloride (N-Boc-D-arginine hydrochloride) is an amino acid derivative with a Boc protecting group, which can be used to synthesize desmopressin with the effects of improving nocturia, urinary incontinence and enuresis .
|
- HY-W047788
-
|
|
Amino Acid Derivatives
|
Others
|
|
H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities .
|
- HY-W005561
-
|
|
Amino Acid Derivatives
|
Others
|
|
H-Dab(Boc)-OMe hydrochloride is an N-terminally protected diaminobutyric acid containing two protecting groups: methoxy (OMe) and tert-butyloxycarbonyl (Boc). H-Dab(Boc)-OMe hydrochloride can be used to synthesize the bifunctional chelator H3Dpaa that can rapidly complex 68Ga under physiological conditions .
|
- HY-W002169
-
- HY-W089292
-
|
|
Peptides
|
Others
|
|
1-Boc-3,3-difluoro-D-proline is an amino acid derivative.
|
- HY-79128
-
- HY-78927
-
|
|
Amino Acid Derivatives
|
Others
|
|
N-Boc-L-Prolinal is a proline with a Boc protecting group, which can be used to synthesize biologically active peptide mimetics, such as the synthesis of Dolastatin 10 (HY-15580) analogs with anti-colon cancer activity .
|
- HY-W141985
-
- HY-W025807
-
- HY-W005295
-
- HY-65000
-
- HY-W109214
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-L-Dap(Boc,Me)-OH is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of diaminopropionic acid containing peptide .
|
- HY-59260
-
- HY-30090
-
- HY-W005308
-
|
|
Amino Acid Derivatives
|
Cancer
|
|
N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity .
|
- HY-P2355
-
- HY-66024
-
- HY-W008359
-
- HY-W043473
-
- HY-P3955
-
- HY-W019205
-
- HY-W013734
-
- HY-W021482
-
- HY-W129448
-
- HY-W004064
-
- HY-W061614
-
|
|
Amino Acid Derivatives
|
Others
|
|
(4R)-1-Boc-4-fluoro-D-proline is an amino acid derivative that can be used for preparation of peptidomimetics, dihydropyridopyrimidines and pyridopyrimidines .
|
- HY-W037441
-
- HY-PS0015
-
|
|
Peptides
|
Others
|
|
Fmoc-Lys(Boc)-Wang resin is a resin containing a lysine protecting group and can be used for the synthesis of peptides .
|
- HY-W010922
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists .
|
- HY-W042478
-
- HY-W090421
-
- HY-W003985
-
- HY-W019032
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .
|
- HY-W141801
-
|
|
Peptides
|
Others
|
|
(R)-Boc-2-methyl-β-Phe-OH is a phenylalanine derivative .
|
- HY-79295
-
|
N-Boc-3-Fluoro-D-phenylalanine; N-tert-Butoxycarbonyl-3-fluoro-D-phenylalanine
|
Amino Acid Derivatives
|
Others
|
|
N-BOC-3-Fluoro-D-phenylalanine is a phenylalanine derivative .
|
- HY-W003499
-
- HY-P2389
-
- HY-P2408
-
- HY-P2388
-
- HY-P2412
-
- HY-W008024
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release .
|
- HY-W046355
-
- HY-W007056
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .
|
- HY-W046071
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-trans-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W106325
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-N-Me-D-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize somatostatin-dopamine chimeric analogs .
|
- HY-P2355A
-
- HY-W142139
-
|
|
Peptides
|
Others
|
|
(S)-Boc-2-amino-5-azido-pentanoic acid (dicyclohexylammonium) is an amino acid derivative, can be used for the synthesis of compounds .
|
- HY-W003222
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-tert-Boc-cis-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-136934
-
|
[Boc-Glu(Obzl)]2-Lys-Ome
|
P-glycoprotein
|
Cancer
|
|
Reversin 205 ([Boc-Glu(Obzl)]2-Lys-Ome) is a P-glycoprotein (ABCB1) inhibitor. Reversin 205 is a peptide chemosensitizer .
|
- HY-P10117
-
- HY-P2055
-
|
|
Peptides
|
Endocrinology
|
|
A-57696 is a cholecystokinin antagonist with selective activity at cortical CCK-B receptors (IC50 = 25 nM). A-57696 behaves as a competitive antagonist in reversing CCK8-stimulated pancreatic alpha-amylase secretion and phosphatidylinositol degradation. A-57696 fails to induce gallbladder contraction and inhibits CCK8-induced contraction. A-57696 behaves as a partial agonist at CCK-B/gastrin receptors on NCI-H345 cells, achieving 80% of the maximal CCK8 response. A-57696 and CCK8 inhibit each other in a calcium mobilization assay .
|
- HY-P10061
-
|
|
Cathepsin
|
Cancer
|
|
Cathepsin K inhibitor 4 is a potent carbohydrazide Cathepsin K inhibitor with IC50s of 13 nM, 269 nM, 296 nM for human, rat, mouse Cathepsin K, respectively .
|
- HY-P2097
-
- HY-P2424
-
|
CCK-J
|
Peptides
|
Others
|
|
Cholecystokinin-J (CCK-J), a cholecystokinin, stimulates Ca 2+ release .
|
- HY-P1994
-
- HY-P2596
-
- HY-W048673
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-Dap(Boc)-OH is an amino acid derivative with a Boc protecting group and can be used in the synthesis of primary amides .
|
- HY-W007599
-
|
|
Peptides
|
Cancer
|
|
(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer, as a nonviral gene vectors, realizes the method in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid also involves in the synthesis of an organic substance that increases the luminescence intensity of alkaline phosphatase substrates .
|
- HY-P3936
-
|
|
Fluorescent Dye
|
Others
|
|
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
|
- HY-W337644
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-L-Homoarg(Et)2-OH hydrochloride is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of homoarginine containing peptide .
|
- HY-P2439
-
|
|
Peptides
|
Others
|
|
MEN 10208 is a neurokinin A antagonist prepared by solid phase synthesis. The Fmoc strategy has more advantages than the Boc strategy in its preparation, and can obtain products with higher yield and purity.
|
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| Purity |
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| Endotoxin Level |
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| Biological Activity |
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| Appearance |
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| Formulation |
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| Storage & Stability |
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| Shipping |
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| Free Sample |
Yes
No
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| Size |
* This product has been "discontinued".
Optimized version of product available:
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-Y0978S
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Boc-Glycine- 15N is the 15N labeled Boc-Glycine[1].
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-
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- HY-41121S
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Boc-Ala-OH-1- 13C is the 13C labeled Boc-Ala-OH[1].
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-
-
- HY-79096S
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BOC-L-Phenylalanine- 13C is a 13C-labeled BOC-L-Phenylalanine. BOC-L-Phenylalanine is a derivative of Phenylalanine[1].
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-
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- HY-41121S4
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Boc-L-Ala-OH- 15N is the 15N labeled Boc-L-Ala-OH.
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-
-
- HY-Y0978S3
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Boc-Glycine- 13C is a 13C-labeled H-Lys-OH.2HCl[1].
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-
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- HY-41121S2
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Boc-L-Ala-OH-2- 13C is a 13C-labeled H-Lys-OH.2HCl[1].
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-
-
- HY-41121S1
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Boc-L-Ala-OH-3- 13C is a 13C-labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
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-
-
- HY-W101495S
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Boc-Leu-OH·H2O- 13C is a 13C-labeled γ-Tocotrienol. γ-Tocotrienol is an active form of vitamin E[1].
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-
-
- HY-Y0978S2
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Boc-Glycine-2- 13C is a 13C-labeled Linuron. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive a
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-
-
- HY-79128S
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Fmoc-L-Lys (Boc)-OH- 15N2 is a 15N-labeled Fmoc-L-Lys (Boc)-OH (HY-79128). Fmoc-L-Lys (Boc)-OH is a lysine derivative .
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-
-
- HY-79128S1
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Fmoc-L-Lys (Boc)-OH- 13C6, 15N2 is a 15N-labeled and 13C-labled Triclabendazole.
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-
-
- HY-101064S
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Fmoc-leucine- 13C is a 13C-labeled Boc-Glycine[1].
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-
-
- HY-W007941S
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Fmoc-Ser(tBu)-OH- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-L-Lys (Boc)-OH[1].
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-
| Cat. No. |
Product Name |
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Classification |
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- HY-75970
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N-Boc-Propargylamine
|
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Alkynes
|
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N-Boc-Propargylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Boc-Propargylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151652
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Alkynes
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Boc-L-Cys(Propargyl)-OH is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH can be used for the research of various biochemical .
|
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- HY-147052
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|
|
Alkynes
PROTAC Synthesis
|
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Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker . Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-151684
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Alkynes
|
|
Boc-Ser(O-propargyl)-OH is a click chemistry reagent containing an alkynes group. Boc-Ser(O-propargyl)-OH can be used for the research of various biochemical .
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-
- HY-151652A
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Alkynes
|
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Boc-L-Cys(Propargyl)-OH (DCHA) is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH (DCHA) can be used for the research of various biochemical .
|
-
- HY-151767
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|
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Alkynes
|
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Boc-Cystamine-Poc (compound H4) is a click chemistry reagent with cystamine building block .
|
-
- HY-140049
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Alkynes
PROTAC Synthesis
|
|
Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140052
-
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|
|
PROTAC Synthesis
Alkynes
|
|
Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140053
-
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|
|
Alkynes
PROTAC Synthesis
|
|
Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140050
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Boc-aminooxy-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140878
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-NH-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140884
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-NH-PEG9-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG9-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140885
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-NH-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG12-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140881
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140882
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Boc-NH-PEG7-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG7-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140883
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG8-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140880
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133500
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-HyNic-PEG2-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-HyNic-PEG2-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133502
-
|
|
|
PROTAC Synthesis
DBCO
|
|
Boc-HyNic-PEG2-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-HyNic-PEG2-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151684A
-
|
|
|
Alkynes
|
|
Boc-Ser(O-propargyl)-OH (DCHA) is a click chemistry reagent containing a propynyl group.
|
-
- HY-140081
-
|
|
|
PROTAC Synthesis
ADC Synthesis
BCN
|
|
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140879
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-N-Amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151676
-
|
N-Boc-O-(2-azidoethyl)-L-tyrosine
|
|
Azide
|
|
Boc-L-Tyr(2-azidoethyl)-OH (N-Boc-O-(2-azidoethyl)-L-tyrosine) is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-133436
-
|
|
|
Alkynes
ADC Synthesis
|
|
Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-aminooxy-amide-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140430
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-Aminooxy-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-Aminooxy-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140432
-
|
|
|
PROTAC Synthesis
Azide
|
|
Boc-Aminooxy-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-Aminooxy-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140433
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-Aminooxy-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140838
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-NH-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140839
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-NH-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140836
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-NH-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140840
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-NH-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG9-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140837
-
|
|
|
PROTAC Synthesis
Azide
|
|
Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133356
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-NH-PEG15-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG15-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151703
-
|
|
|
Azide
|
|
Boc-D-Lys(N3)-OH is a Boc-protected amino acid derivative, can be used as a click chemistry reagent and an intermediate for synthesis of linkers . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-140835
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-N-Amido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133501
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-HyNic-PEG2-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-HyNic-PEG2-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140834
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-N-Amido-PEG2-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-N-Amido-PEG2-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151763
-
|
|
|
Azide
|
|
Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151846
-
|
|
|
Alkynes
|
|
Boc-L-Pra-OH (DCHA) is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-138474
-
|
|
|
Azide
PROTAC Synthesis
|
|
Boc-PEG1-PPG2-C2-azido is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-PEG1-PPG2-C2-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132119
-
|
|
|
PROTAC Synthesis
Azide
|
|
Boc-NHCH2CH2-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NHCH2CH2-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151722
-
|
|
|
Azide
|
|
Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W250992
-
|
|
|
Azide
|
|
Boc-L-Lys(N3)-OH CHA is a click chemistry reagent containing an azide . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151784
-
|
|
|
Azide
|
|
Boc-D-Aza-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-130897
-
|
|
|
PROTAC Synthesis
Azide
|
|
Boc-NH-PEG11-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG11-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130899
-
|
|
|
PROTAC Synthesis
Azide
|
|
Boc-NH-PEG23-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG23-CH2CH2N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151824
-
|
|
|
Alkynes
|
|
Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W419403
-
|
|
|
Azide
|
|
Boc-D-Aza-OH (CHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151718
-
|
|
|
Azide
|
|
Boc-L-Tyr(PEG(3)-N3)-OH is a click chemistry agent containing azide. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-151718A
-
|
|
|
Azide
|
|
Boc-L-Tyr(PEG(3)-N3)-OH DCHA is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-151858
-
|
|
|
Azide
|
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Boc-L-Lys(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-151703A
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Azide
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Boc-D-Lys(N3)-OH CHA is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-140562
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Azide
PROTAC Synthesis
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N-(Azido-PEG2)-N-Boc-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140565
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PROTAC Synthesis
Azide
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N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140563
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Azide
PROTAC Synthesis
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|
N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140567
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Azide
PROTAC Synthesis
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|
N-(Azido-PEG4)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140566
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Azide
PROTAC Synthesis
|
|
N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Azido-PEG4-N-Boc-N-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130375
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PROTAC Synthesis
Alkynes
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Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG8-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130380
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PROTAC Synthesis
Alkynes
|
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Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG7-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-130384
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PROTAC Synthesis
Alkynes
|
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Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG6-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140027
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PROTAC Synthesis
Alkynes
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Propargyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140028
-
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Alkynes
PROTAC Synthesis
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Propargyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140029
-
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Alkynes
PROTAC Synthesis
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Propargyl-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG10-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140030
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Alkynes
PROTAC Synthesis
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Propargyl-PEG14-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG14-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130597
-
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Alkynes
PROTAC Synthesis
|
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Propargyl-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-138733
-
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PROTAC Synthesis
Alkynes
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Propargyl-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG13-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140026
-
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PROTAC Synthesis
Alkynes
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Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141282
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Tetrazine
|
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Methyltetrazine-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141281
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Tetrazine
|
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Methyltetrazine-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-140051
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t-Boc-aminooxy-PEG3-Propargyl
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Alkynes
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N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC .
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- HY-140075
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BCN
PROTAC Synthesis
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endo-BCN-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG6-Boc is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140074
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BCN
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endo-BCN-PEG4-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
- HY-140781
-
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PROTAC Synthesis
Azide
|
|
Azido-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140775
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Azide
PROTAC Synthesis
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|
Azido-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140780
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Azide
PROTAC Synthesis
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Azido-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG9-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140777
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Azide
PROTAC Synthesis
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Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140795
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Azide
PROTAC Synthesis
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Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140778
-
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Azide
PROTAC Synthesis
|
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Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140782
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Azide
PROTAC Synthesis
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Azido-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG12-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140784
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Azide
PROTAC Synthesis
|
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Azido-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140785
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Azide
PROTAC Synthesis
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Azido-PEG36-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG36-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-133319
-
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Azide
PROTAC Synthesis
|
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Azido-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG24-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-138457
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Azide
PROTAC Synthesis
|
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Azido-PEG20-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG20-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130742
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Azide
PROTAC Synthesis
|
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Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140031
-
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PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-OCH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140107
-
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Azide
PROTAC Synthesis
|
|
Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azidoethyl-SS-PEG2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140293
-
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DBCO
PROTAC Synthesis
|
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DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-42618
-
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PROTAC Synthesis
ADC Synthesis
Azide
|
|
Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140779
-
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Azide
PROTAC Synthesis
|
|
Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-C2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-130389
-
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|
|
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG4-O-C1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140599
-
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|
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Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-S-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140612
-
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PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140776
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-C2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140793
-
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|
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Azide
PROTAC Synthesis
|
|
Azido-PEG2-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140796
-
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|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140792
-
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|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-130293
-
|
|
|
Alkynes
ADC Synthesis
PROTAC Synthesis
|
|
Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-153370
-
|
|
|
DBCO
|
|
DBCO-PEG3-oxyamine-Boc hydrochloride is an ADC linker . DBCO-PEG3-oxyamine-Boc (hydrochloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140604
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG3-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140786
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG4-amido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-130690
-
|
|
|
Alkynes
PROTAC Synthesis
ADC Synthesis
|
|
Propargyl-PEG1-SS-PEG1-C2-Boc is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG1-SS-PEG1-C2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140032
-
|
Alkyne-ethyl-PEG1-t-butyl ester
|
|
PROTAC Synthesis
Alkynes
|
|
Alkyne-ethyl-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-ethyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140292
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG9-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG9-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140291
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140289
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG1-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140290
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG2-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-126884
-
|
|
|
PROTAC Synthesis
ADC Synthesis
DBCO
|
|
DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-170315
-
|
|
|
Alkynes
|
|
Ethyne-C2-Pip-CO-Pip-Boc (Compound 21) is a PROTAC linker. Ethyne-C2-Pip-CO-Pip-Boc can be used to synthesize QA-68 (HY-150797) .
|
- HY-43721
-
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|
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PROTAC Synthesis
Alkynes
|
|
N-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277 (HY-130122) . N-Boc-4-pentyne-1-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-141279
-
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|
|
Tetrazine
|
|
Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141280
-
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|
|
Tetrazine
|
|
Methyltetrazine-PEG24-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-42489
-
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Azide
PROTAC Synthesis
ADC Synthesis
|
|
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG3-CH2CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140868
-
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|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG3)-N-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG3-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140867
-
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|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140869
-
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|
|
PROTAC Synthesis
Azide
|
|
N-(Azido-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140054
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
t-Boc-aminooxy-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-aminooxy-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140077
-
|
|
|
BCN
|
|
endo-BCN-PEG3-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
- HY-140816
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140817
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140794
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG3-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-C-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140849
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG3-Ala-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Ala-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-138377
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG8-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-138388
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG4-formylhydrazine-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-formylhydrazine-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-138464
-
|
|
|
Azide
PROTAC Synthesis
|
|
Br-Boc-C2-azido is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Br-Boc-C2-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140089
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
N-Boc-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-133461
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG6-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133462
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-151841
-
|
|
|
Azide
|
|
N3-L-Lys(Boc)-OH is a click chemistry reagent containing an azide group . N3-L-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140294
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-C2-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C2-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140295
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-C3-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C3-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140434
-
|
|
|
Azide
PROTAC Synthesis
|
|
t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140431
-
|
|
|
PROTAC Synthesis
Azide
|
|
t-Boc-Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-Aminooxy-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-151654
-
|
|
|
Azide
|
|
N3-D-Lys(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-151729
-
|
|
|
Azide
|
|
N3-D-Dab(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Dab(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-151735
-
|
|
|
Azide
|
|
N3-L-Dab(Boc)-OH is a click chemistry reagent containing an azide group. N3-L-Dab(Boc)-OH can be used for the research of various biochemical . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-151764
-
|
|
|
Azide
ADC Synthesis
|
|
N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-151764A
-
|
|
|
Azide
ADC Synthesis
|
|
N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-140788
-
|
5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester
|
|
Azide
PROTAC Synthesis
|
|
Azide-PEG9-amido-C4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140790
-
|
13-(Azide-PEG9-ethylcarbamoyl)tridecanoic t-butyl ester
|
|
Azide
PROTAC Synthesis
|
|
Azide-PEG9-amido-C12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C12-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140789
-
|
9-(Azide-PEG9-ethylcarbamoyl)nonanoic t-butyl ester
|
|
Azide
PROTAC Synthesis
|
|
Azide-PEG9-amido-C8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140787
-
|
17-(Azide-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester
|
|
PROTAC Synthesis
Azide
|
|
Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG6-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140791
-
|
17-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester
|
|
Azide
PROTAC Synthesis
|
|
Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140556
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-Boc-N-bis(PEG4-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(PEG4-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140555
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-Boc-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-151736
-
|
|
|
Azide
|
|
N3-L-Dap(Boc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-L-Dap(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-130312
-
|
|
|
PROTAC Synthesis
Azide
|
|
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140569
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(PEG1-OH)-N-Boc-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140090
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140093
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-161792
-
|
|
|
Azide
|
|
N3-C5-O-C-Boc is a linker, which can be utilized for the synthesis of PROTAC SARS-CoV-2 Mpro degrader-3 (HY-161789) .
|
- HY-140524
-
|
|
|
PROTAC Synthesis
Azide
|
|
N-(Azido-PEG2)-N-Boc-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140525
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG2)-N-Boc-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140526
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG3)-N-Boc-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140094
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-130598
-
|
|
|
PROTAC Synthesis
Azide
|
|
N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs N-(Azido-PEG3)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140092
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140561
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140554
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-Boc-N-bis(C2-PEG1-azide) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(C2-PEG1-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140871
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Boc-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Boc-PEG3)-N-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140872
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Boc-PEG2)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Boc-PEG2)-N-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140560
-
|
|
|
PROTAC Synthesis
Azide
|
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N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140559
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PROTAC Synthesis
Azide
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N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140564
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PROTAC Synthesis
Azide
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N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-141287
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Azide
PROTAC Synthesis
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N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151677
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Azide
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(2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide . (2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151677A
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Azide
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(2R,4S)-Boc-D-Pro(4-N3)-OH DCHA is a click chemistry reagent containing an azide . (2R,4S)-Boc-D-Pro(4-N3)-OH (DCHA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151848
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Azide
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(2R,4R)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-168196
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Alkynes
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DYR530-Boc is a target protein ligand activity control that can be used to synthesize PROTAC (HY-168194) .
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| Cat. No. |
Product Name |
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Classification |
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- HY-RS01567
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siRNAs
Pre-designed siRNA Sets
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BOC Human Pre-designed siRNA Set A contains three designed siRNAs for BOC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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- HY-152502
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Nucleosides and their Analogs
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5-N-Boc-aminomethyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
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- HY-154111
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Nucleosides and their Analogs
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8-(N-Boc-aminomethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
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- HY-W800843
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Cationic Lipids
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tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate is an aminolipid featuring a Boc-protected primary amine, a propylamine spacer attached to an octanoate chain and a C11 chain.
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- HY-W800849
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Cationic Lipids
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BP Lipid 315 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. One of these esters features a symmetrical branched C17 tail, while the other is an asymmetric C11 tail.
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