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Results for "

sensitive

" in MedChemExpress (MCE) Product Catalog:

By Targets:	VAP-1 (1) 5-HT Receptor (1) Adrenergic Receptor (3) Akt (4) Aldose Reductase (1) Amino Acid Derivatives (1) Amyloid-β (1) Angiotensin Receptor (3) Antibiotic (16) Antibody-Drug Conjugates (ADCs) (2) Antifolate (1) Apoptosis (28) Aryl Hydrocarbon Receptor (1) Aurora Kinase (1) Autophagy (24) Bacterial (44) Bcr-Abl (1) Biochemical Assay Reagents (18) Calcium Channel (26) Carbonic Anhydrase (6) Carboxypeptidase (1) Caspase (1) Cathepsin (1) CDK (1) CFTR (4) Checkpoint Kinase (Chk) (1) Cryptochrome (1) Cytochrome P450 (2) DAPK (1) Dihydrofolate reductase (DHFR) (1) Dipeptidyl Peptidase (3) DNA Alkylator/Crosslinker (1) DNA Stain (1) DNA/RNA Synthesis (7) Drug Intermediate (1) Drug Metabolite (9) Drug-Linker Conjugates for ADC (3) EGFR (5) Endogenous Metabolite (22) Epigenetic Reader Domain (1) ERK (2) Estrogen Receptor/ERR (2) FAAH (1) Fatty Acid Synthase (FASN) (1) FLT3 (1) Fluorescent Dye (128) Formyl Peptide Receptor (FPR) (2) Free Fatty Acid Receptor (1) Fungal (2) G-quadruplex (1) GABA Receptor (9) Glucocorticoid Receptor (1) GLUT (1) Glycosidase (1) Guanylate Cyclase (1) HBV (1) HDAC (2) Herbicide (5) HIF/HIF Prolyl-Hydroxylase (1) Histamine Receptor (2) HIV (2) HIV Protease (2) HSP (2) HSV (2) IGF-1R (2) iGluR (9) Influenza Virus (4) Insecticide (1) Interleukin Related (1) Isotope-Labeled Compounds (15) JAK (1) Keap1-Nrf2 (1) Ligands for Target Protein for PROTAC (1) Lipase (5) Liposome (5) MAGL (1) MALT1 (1) MCHR1 (GPR24) (2) MDM-2/p53 (2) Melanocortin Receptor (2) mGluR (3) MicroRNA (1) Microtubule/Tubulin (4) Mitochondrial Metabolism (5) Mitophagy (2) MMP (6) Monoamine Oxidase (8) Na+/Ca2+ Exchanger (1) nAChR (3) NADPH Oxidase (1) Neurokinin Receptor (1) NF-κB (1) Opioid Receptor (2) Organoid (3) P-glycoprotein (4) P2X Receptor (1) Parasite (24) PARP (1) PD-1/PD-L1 (2) Peptide-Drug Conjugates (PDCs) (2) Phosphatase (6) Phosphodiesterase (PDE) (2) Pim (1) PKA (1) PKC (2) Polo-like Kinase (PLK) (1) Potassium Channel (91) PPAR (1) Prostaglandin Receptor (2) PROTAC Linkers (2) PROTACs (1) Proteasome (1) Protein Arginine Deiminase (1) Radionuclide-Drug Conjugates (RDCs) (1) Ras (2) Reactive Oxygen Species (10) RET (1) Reverse Transcriptase (1) Ser/Thr Protease (1) SHP2 (1) Smo (1) Sodium Channel (29) SphK (1) Survivin (1) TAM Receptor (1) Thyroid Hormone Receptor (1) Topoisomerase (6) TRP Channel (2) TrxR (1) VD/VDR (1) VSV (2)
By Research Areas:	Cancer (118) Cardiovascular Disease (44) Endocrinology (10) Infection (77) Inflammation/Immunology (41) Metabolic Disease (42) Neurological Disease (92)
Click Chemistry:	Labeling and Fluorescence Imaging (5) PROTAC Synthesis (1) Azide (3) Alkynes (4)
Oligonucleotides:	Nucleotides and their Analogs (2) Phospholipids (2) Cationic Lipids (3)

522

Inhibitors & Agonists

Screening Libraries

103

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

CypHer 5	Fluorescent Dye	Others
CypHer 5 is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. CypHer 5 has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. CypHer 5 has been used as a pH sensor of lysosomal compartments .

Z-Arg-Arg-βNA acetate	Cathepsin	Others
Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins .

NBD-X, SE	Fluorescent Dye	Others
NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates .

N-(2-Aminoethyl)maleimide hydrochloride 2-Maleimidoethylamine hydrochloride	Biochemical Assay Reagents	Cancer
N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a cross-linker. N-(2-Aminoethyl)maleimide hydrochloride can be used to prepare MMP-2 sensitive nanosystem, and for cancer research .

Glibornuride	Potassium Channel	Metabolic Disease
Glibornuride is a blocker of ATP-sensitive K ⁺ channels (K_ATP channel) with a pK_i of 5.75 . Antidiabetic agent .

Uracil DNA Glycosylase (UDG/UNG), heat-sensitive Heat-sensitive UDG	DNA/RNA Synthesis	Cancer
Uracil DNA Glycosylase (UDG/UNG), heat-sensitive (Heat-sensitive UDG) can catalyze the hydrolysis of the N-glycosidic bond between the uracil base and the sugar phosphate backbone in the DNA chain containing uracil, releasing free uracil. Uracil DNA Glycosylase (UDG/UNG), heat-sensitive eliminates the carryover contamination dUTP-incorporated amplification products .

Patman	Fluorescent Dye	Others
Patman is a polarity sensitive dye .

Fura PE-3 potassium	Fluorescent Dye	Others
Fura PE-3 potassium is a Ca ²⁺sensitive fluorophore. Fura PE-3 potassium loads in IPA (intrapulmonary arteries) and MA (mesenteric resistance arteries) for the research of vasoconstriction .

PSA-IN-1	Others	Neurological Disease
PSA-IN-1 (compound 19) is a *puromycin sensitive* aminopeptidase (PSA) inhibitor with IC₅₀** at 7 nM. PSA-IN-1 has analgesic activity .

Calcium alginate	Biochemical Assay Reagents	Inflammation/Immunology
Calcium alginate is a biopolymer that can be used for developing oral agent-delivery systems . Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media .

Di-2-ANEPEQ	Fluorescent Dye	Neurological Disease
Di-2-ANEPEQ is a voltage sensitive membrane potential fluorescence dye. Di-2-ANEPEQ can be used for the evaluation of voltage-sensitive fluorescence dyes for monitoring neuronal activity in the embryonic central nervous system .

Glibornuride (Standard)	Potassium Channel	Metabolic Disease
Glibornuride (Standard) is the analytical standard of Glibornuride. This product is intended for research and analytical applications. Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75 . Antidiabetic agent .

Nile blue chloride	Fluorescent Dye	Others
Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics .

PXS-4728A BI-1467335	Monoamine Oxidase	Inflammation/Immunology
PXS-4728A (BI-1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO). PXS-4728A ameliorates chronic obstructive pulmonary disease in mice .

SW157765	GLUT	Cancer
SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double mutant NSCLC cells are selectively sensitive to the SW157765, due to the convergent consequences of dual KRAS and NRF2 modulation of metabolic and xenobiotic gene regulatory programs .

MK-2206	Organoid Akt Autophagy Apoptosis	Cancer
MK-2206 is an orally active, highly potent and selective allosteric Akt inhibitor, with IC₅₀s of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. Many breast cancer cell lines, and PIK3CA-mutant and cell lines with PTEN loss are sensitive to MK-2206. MK-2206 has anticancer activities .

ACT-451840	Parasite	Infection
ACT-451840 is an orally active, potent and low-toxicity compound, showing activity against sensitive and resistant plasmodium falciparum strains. ACT-451840 targets all asexual blood stages of the parasite, has a rapid onset of action. ACT-451840 behaves in a way similar to artemisinin derivatives, with very rapid onset of action and elimination of parasite. ACT-451840 can be used for the research of malarial .

9-Amino-6-chloro-2-methoxyacridine	Fluorescent Dye	Others
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H ⁺/solute antiport system .

MK-2206 free base	Organoid Akt Autophagy Apoptosis	Cancer
MK-2206 free base is an orally active, highly potent and selective allosteric Akt inhibitor, with IC₅₀s of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. Many breast cancer cell lines, and PIK3CA-mutant and cell lines with PTEN loss are sensitive to MK-2206 free base. MK-2206 free base has anticancer activities .

FM-red PSH-red	Fluorescent Dye	Neurological Disease
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .

Eprociclovir A-5021	DNA/RNA Synthesis	Infection
Eprociclovir is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir can be used in studies interfered with by sensitive viruses .

Eprociclovir potassium A-5021 potassium	DNA/RNA Synthesis	Infection
Eprociclovir potassium is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir potassium is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir potassium is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir potassium can be used in studies interfered with by sensitive viruses .

Eprociclovir sodium A-5021 sodium	DNA/RNA Synthesis	Infection
Eprociclovir sodium is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir sodium is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir sodium is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir sodium can be used in studies interfered with by sensitive viruses .

Dactimicin sulfate SF-2052 sulfate	Antibiotic	Infection
Dactimicin sulfate (SF-2052 sulfate) is an antibiotic produced by Dactylosporangium matsuzakiense and belongs to the fortimicin antibiotic family. Dactimicin sulfate is an aminoglycoside antibiotic containing a carboximido group and inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria. Dactimicin sulfate can be used in research on infections caused by sensitive bacteria .

SKI-178	SphK Apoptosis	Cancer
SKI-178 is a potent sphingosine kinase-1 (SphK1) and SphK2 inhibitor. SKI-178 is cytotoxic at IC₅₀ concentrations ranging from 1.8 to 0.1 μM in both agent sensitive and multi-agent resistant cancer cell lines (i.e., MTR3, NCI-ADR and HL60/VCR cells). SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines .

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine	Liposome	Others
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs .

NOX2-IN-3	NADPH Oxidase	Cancer
NOX2-IN-3 (compound 3) is an inhibitor of NOX2 (NADPH Oxidase 2). NOX2-IN-3 sensitizes tumor cells to MRTX1133 (HY-134813) .

Fura Red	Fluorescent Dye	Others
Fura Red is a Ca ²⁺-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca ²⁺] .

Acetyl tetrapeptide-15	Opioid Receptor	Neurological Disease
Acetyl tetrapeptide-15 is a synthetic peptide used in the cosmetics for sensitive skin. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway .

MSOP	mGluR	Neurological Disease
MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent K_D of 51 μM for the L-AP4-sensitive presynaptic mGluR.

MPPG	mGluR	Neurological Disease
MPPG is a potent and selective *L-AP4*-sensitive receptor antagonist with an k_D value of 9.2 μM, being tested on the neonatal rat spinal cord .

MMBC	Fluorescent Dye	Others
MMBC is a sulfhydryl-sensitive fluorophore .

Fmoc-Lys(5-FITC)-OH	Fluorescent Dye	Others
Fmoc-Lys(5-FITC)-OH is a marker for polypeptides or proteins. FITC is a fluorescence probe for the labeling of amines. FITC is a pH- and Cu ²⁺-sensitive fluorescence dye .

McN5691 RWJ26240	Calcium Channel	Cardiovascular Disease
McN5691 is a voltage-sensitive calcium channel blocker.

Oxonol 595	Fluorescent Dye	Others
Oxonol 595 is a voltage-sensitive fluorescent dye .

Prodan	Fluorescent Dye	Others
Prodan, a solvatochromic fluorophore, has been used as a microenvironment-sensitive membrane reporter. Based on the chemistry of Prodan, fluorescent nucleosides are designed and synthesized.The fluorescent nucleosides sensitively varied the Stokes shift values depending on the orientational polarizability of the solvent .

Levcromakalim 4 Publications Verification (-)-Cromakalim; BRL 38227	Potassium Channel	Cardiovascular Disease
Levcromakalim ((-)-Cromakalim) is an ATP-sensitive K ⁺ channel (K_ATP) activator.

Sudocetaxel	Microtubule/Tubulin	Cancer
Sudocetaxel is a microtubule depolymerization inhibitor for pH-sensitive docetaxel delivery.

RH 795	Fluorescent Dye	Others
RH 795 is a fast-response voltage-sensitive dye .

Paederosidic acid methyl ester	Potassium Channel	Neurological Disease
Paederosidic acid methyl ester is a ATP‐sensitive K ⁺ channel activator, isolated from P. scandens. Paederosidic acid methyl ester exhibits significant central analgesic activity, and enhances the threshold of pain by activating ATP‐sensitive K ⁺ channel in the brain and spinal cord level .

Bromochlorophenol Blue sodium salt	Biochemical Assay Reagents	Others
Bromochlorophenol Blue sodium salt, an acid-sensitive dye, is a pH-indicating dye .

L-ANAP hydrochloride	Fluorescent Dye	Others
L-ANAP hydrochloride is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa).

Cevadine	Sodium Channel Parasite	Infection
Cevadine is a voltage-sensitive sodium channel agonist. Cevadine has insecticidal activity .

Oxonol V	Fluorescent Dye	Others
Oxonol V is a slow-response sensitive probe for measuring cellular membrane potential.

DiBAC4(5)	Fluorescent Dye	Neurological Disease
DiBaC4(5) is a fluorescent voltage-sensitive dye that can be used to monitor the transmembrane potentials when Papain-dissociated retinal cells from adult zebrafish were exposed to GABAergic ligands. DiBaC4(5) is a potential-sensitive fluorescence dye .

NS-8	Potassium Channel	Endocrinology
NS-8, a pyrrole derivative, activates the Ca ²⁺-sensitive k ⁺-channel. NS-8 can suppress the micturition reflex by decreasing afferent pelvic nerve activity. NS-8 can be used in the research of urinary frequency and incontinence .

Cat. No.	Product Name

HY-E0077

Adhesive Aluminium Foil Plate Seal

0 compounds

MCE adhesive aluminium foil plate seals are of strong adhesive that can reduce chance of well-to-well contamination and sample evaporation when applied to microplates. This aluminium foil seal is suitable for long-term storage of samples at -80°C. The high integrity sealing materials give the best protection against evaporation and contamination. The aluminium foil seal features excellent chemical resistance to DMSO and DNase- & RNase- free. MCE adhesive foil seal is pierceable, peelable and easy-to-use.

HY-L118

Sodium Channel Blocker Library

151 compounds

Sodium channels conduct sodium ions (Na+) through a cell's plasma membrane that are the source of excitatory currents for the nervous system and muscle. Na channels are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change (Voltage-gated, voltage-sensitive, or voltage-dependent sodium channel also called VGSCs or Nav channel) or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). Dysfunction in voltage-gated sodium channels correlates with neurological and cardiac diseases, including epilepsy, myopathies, pain and cardiac arrhythmias. Sodium channel blockers are used in the treatment of cardiac arrhythmia, pain and convulsion.

MCE offers a unique collection of 151 sodium channel blocker and antagonists, all of which have the identified inhibitory effect on sodium channels. MCE Sodium Channel Blocker Library can be used for neurological and cardiac diseases drug discovery and sodium channel research.

HY-L022M

FDA-Approved Drug Library Mini

3,102 compounds

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.

MCE owns a unique collection of 3,102 approved compounds which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties. The package of this library is 96-well microplate with peelable foil seal, which makes the screening process easier and faster.

HY-L075

Anti-Lung Cancer Compound Library

2,148 compounds

Lung cancer is a major global health problem, as it is the leading cause of cancer-related deaths worldwide. Lung cancer is divided into two categories: small cell lung cancer and non-small cell lung cancer (NSCLC). Non-small cell lung cancer accounts for about 85 percent of lung cancers.

As with all cancers, lung cancer may be treated with surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy or a combination thereof. Targeted therapy is one of the most exciting developments in lung cancer medicine, especially for NSCLC. Extensive genomic characterization of NSCLC has led to the identification of molecular subtypes of NSCLC that are oncogene addicted and exquisitely sensitive to targeted therapies. These include activating mutations in epidermal growth factor receptor (EGFR) and BRAF or echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusions and ROS1 receptor tyrosine kinase fusions. These are important targets for target therapy.

MCE offers a unique collection of 2,148 compounds with identified and potential anti-lung cancer activity. These compounds target lung cancer’s major targets and signaling pathways. MCE anti-lung cancer compound library is a useful tool for anti-lung cancer drugs screening and other related research.

Cat. No.	Product Name	Type

HY-D1563

CypHer 5	Dyes
CypHer 5 is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. CypHer 5 has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. CypHer 5 has been used as a pH sensor of lysosomal compartments .

HY-134566

NBD-X, SE	Fluorescent Dyes/Probes
NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates .

HY-D1427

Di-2-ANEPEQ	Fluorescent Dyes/Probes
Di-2-ANEPEQ is a voltage sensitive membrane potential fluorescence dye. Di-2-ANEPEQ can be used for the evaluation of voltage-sensitive fluorescence dyes for monitoring neuronal activity in the embryonic central nervous system .

HY-118155

9-Amino-6-chloro-2-methoxyacridine	Fluorescent Dyes/Probes
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H ⁺/solute antiport system .

HY-D1260

FM-red PSH-red	Fluorescent Dyes/Probes
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .

HY-D1512

Oxonol 595	Fluorescent Dyes/Probes
Oxonol 595 is a voltage-sensitive fluorescent dye .

HY-D0074

Prodan	Fluorescent Dyes/Probes
Prodan, a solvatochromic fluorophore, has been used as a microenvironment-sensitive membrane reporter. Based on the chemistry of Prodan, fluorescent nucleosides are designed and synthesized.The fluorescent nucleosides sensitively varied the Stokes shift values depending on the orientational polarizability of the solvent .

HY-D1487

Patman	Dyes
Patman is a polarity sensitive dye .

HY-104056

Fura Red	Fluorescent Dyes/Probes
Fura Red is a Ca ²⁺-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca ²⁺] .

HY-W353607A

Bromochlorophenol Blue sodium salt	Dyes Indicators
Bromochlorophenol Blue sodium salt, an acid-sensitive dye, is a pH-indicating dye .

HY-101937B

L-ANAP hydrochloride	Fluorescent Dyes/Probes
L-ANAP hydrochloride is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa).

HY-130210

Oxonol V	Fluorescent Dyes/Probes
Oxonol V is a slow-response sensitive probe for measuring cellular membrane potential.

HY-D1092

DiBAC4(5)	Fluorescent Dyes/Probes
DiBaC4(5) is a fluorescent voltage-sensitive dye that can be used to monitor the transmembrane potentials when Papain-dissociated retinal cells from adult zebrafish were exposed to GABAergic ligands. DiBaC4(5) is a potential-sensitive fluorescence dye .

HY-D0035

MPAC-Br	Fluorescent Dyes/Probes
MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

HY-D1631

Calcium Green-5N AM	Fluorescent Dyes/Probes
Calcium Green-5N AM is a novel Ca ²⁺-sensitive fluorescent probe. Calcium Green-5N AM shows enhancement in fluorescence intensity on binding Ca ²⁺, and can monitor free Ca ²⁺ in neurons .

HY-101937

L-ANAP	Fluorescent Dyes/Probes
L-ANAP is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa) .

HY-D1470

BADAN	Fluorescent Dyes/Probes
BADAN (6-Bromoacetyl-2-dimethylaminonaphthalene) is a polarity-sensitive fluorescent probe .

HY-D1750

Rhodamine B thiolactone	Fluorescent Dyes/Probes
Rhodamine B thiolactone is a high-sensitive Hg ²⁺ indicator used for measuring Hg ²⁺ concentration.

HY-101892

DiBAC4(3) 5+ Cited Publications	Fluorescent Dyes/Probes
DiBAC4(3) is a voltage-sensitive fluorescent dye (λ_ex=490 nm, λ_em=505 nm).

HY-P2685

MeOSuc-Ala-Ala-Pro-Val-pNA	Chromogenic Substrates
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .

HY-130025

HKOCl-3 2 Publications Verification	Fluorescent Dyes/Probes
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.E_x: 490 nm; E_m 527 nm .

HY-W040230

Acrylodan	Fluorescent Dyes/Probes
Acrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys ³⁴ .

HY-D1459

BODIPY 665/676	Fluorescent Dyes/Probes
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation .

HY-15909

BCIP BCIP p-toluidine salt; X-phosphate p-toluidine salt	Chromogenic Substrates
BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.

HY-D2115

NBDT	Fluorescent Dyes/Probes
NBDT is sensitive and selective light-up fluorescent probe for monitoring gallium and chromium ionsin vitro and in vivo and can be detected at 574 nM .

HY-D0817

Rhodamine 110 Rhodamine 110 chloride; RH110	Fluorescent Dyes/Probes
Rhodamine 110 is a sensitive and selective substrate for assaying proteinases in solution or inside living cells. The excitation wavelength is 498 nm and the emission wavelength is 521 nm .

HY-101891

Di-8-ANEPPS 1 Publications Verification	Fluorescent Dyes/Probes
Di-8-ANEPPS is a naphthylstyryl voltage-sensitive dye, shifting both their fluorescence excitation and emission spectra upon changes in V_m .

HY-114958

RH 421	Fluorescent Dyes/Probes
RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase .

HY-D1091

DiSBAC2(3)	Fluorescent Dyes/Probes
DiSBAC2(3) is an anionic membrane-potential-sensitive dye. DiSBAC2(3) is a plasma membrane potential indicator .

HY-D2481

Asante potassium green-2 (TMA) APG-2 (TMA)	Fluorescent Dyes/Probes
Asante potassium green-2 (APG-2) TMA is a cell-impermeable K ⁺ (potassium) sensitive fluorescent indicator (excitation/emission = 525/545 nm) .

HY-D2482

Asante potassium green-1 AM APG-1 AM	Fluorescent Dyes/Probes
Asante potassium green-1 AM (APG-1 AM) is a cell-permeable K ⁺ (potassium) sensitive fluorescent indicator (excitation/emission = 525/545 nm).

HY-D2483

Asante potassium green-1 (TMA) APG-1 (TMA)	Fluorescent Dyes/Probes
Asante potassium green-1 (APG-1) TMA is a cell-impermeable K ⁺ (potassium) sensitive fluorescent indicator (excitation/emission = 525/545 nm) .

HY-D1442

SBFI tetraammonium	Fluorescent Dyes/Probes
SBFI (tetraammonium), the tetraammonium salt of SBFI, is a sodium fluorescence indicator. SBFI (tetraammonium) is sodium-sensitive dye. The excitation wavelength is set 333 nm, and the emission wavelength is 539 nm for SBFI .

HY-D1180

DTTCI 3,3′-Diethylthiatricarbocyanine iodide	Dyes
DTTCI (3,3′-Diethylthiatricarbocyanine iodide) is an infrared photographic sensitizing dye. DTTCI is a highly sensitive chiroptical reporter of DNA helicity and sequence .

HY-157036

INSA	Fluorescent Dyes/Probes
INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences .

HY-D0981

7-Amino-4-(trifluoromethyl)coumarin 1 Publications Verification Coumarin 151; AFC	Fluorescent Dyes/Probes
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.

HY-138760

SEluc-2	Fluorescent Dyes/Probes
SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells .

HY-D0075

DHPDS disodium salt	Fluorescent Dyes/Probes
DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver .

HY-D1556

18:1 PE CF 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) ammonium	Fluorescent Dyes/Probes
DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids .

HY-101882

BCECF 1 Publications Verification 2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein	Fluorescent Dyes/Probes
BCECF is a *pH-sensitive* fluorescent dye. BCECF allows measurements in the physiological pH range 6.0–8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.

HY-D0893

NSP-SA-NHS	Fluorescent Dyes/Probes
NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed .

HY-D1151

HKOH-1 1 Publications Verification	Fluorescent Dyes/Probes
HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-D1457

DND-189	Fluorescent Dyes/Probes
DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .

HY-D1148

HKGreen-4I 1 Publications Verification	Fluorescent Dyes/Probes
HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO ^- in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .

HY-D1159

HKOH-1r 5 Publications Verification	Fluorescent Dyes/Probes
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-D0023

Pyranine 1 Publications Verification HPTS; Solvent Green 7	Fluorescent Dyes/Probes
Pyranine (HPTS; Solvent Green 7) is a pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu ⁺ ion(λex=450 nm, λem=510 nm) .

HY-130022

HKPerox-1 1 Publications Verification	Fluorescent Dyes/Probes
HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H₂O₂ in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .

HY-D1157

HKPerox-2 4 Publications Verification	Fluorescent Dyes/Probes
HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H₂O₂ in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .

HY-D1094

Carboxy-SNARF 1 (5/6-mixture) SNARF 1	Fluorescent Dyes/Probes
Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH. Carboxy-SNARF 1 (5/6-mixture) can be used for measurement pH .

HY-137296

Lumogallion 1 Publications Verification	Fluorescent Dyes/Probes
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm .

Cat. No.	Product Name	Type

HY-W068119A

N-(2-Aminoethyl)maleimide hydrochloride 2-Maleimidoethylamine hydrochloride	Biochemical Assay Reagents
N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a cross-linker. N-(2-Aminoethyl)maleimide hydrochloride can be used to prepare MMP-2 sensitive nanosystem, and for cancer research .

HY-142989

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine

Drug Delivery

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs .

HY-W016473

Adamantane-carboxylic acid	Biochemical Assay Reagents
Adamantane-carboxylic acid is an antibacterial agent that is effective in inhibiting the growth of Gram-positive bacteria but is less sensitive to Gram-negative bacteria .

HY-W353607A

Bromochlorophenol Blue sodium salt	Dyes Indicators
Bromochlorophenol Blue sodium salt, an acid-sensitive dye, is a pH-indicating dye .

HY-111157

Dezinamide AHR11748; AN051; ADD94057	Cell Assay Reagents
Dezinamide (ADD94057) is an antiepileptic agent. Dezinamide binds to the voltage-sensitive sodium channel .

HY-144025

DOBAQ	Drug Delivery
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .

HY-W134005

Mg(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate	Chelators
Mg(II)-EDTA (disodium tetrahydrate) is an ion-chelating agent that can be used to prepare reagents for ion-sensitive experiments .

HY-W441021

DSPE-Pyrene	Drug Delivery
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.

HY-W250149

Chlorophosphonazo III	Biochemical Assay Reagents
Chlorophosphonazo III is a sensitive reagent for both calcium and magnesium. It is possible to determine calcium alone at pH 2.2 and calcium and magnesium at pH 7.0. Chlorophosphonazo III can also be used for the spectrophotometric determination of titanium, zirconium, thorium, and scandium, quinquevalent actinide elements, and protactinium .

HY-157917

Nitro-PAPS disodium dihydrate	Chelators
Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V .

HY-W699926

(R)-Naproxen acyl-β-D-glucuronide (R)-Naproxen-β-D-glucuronide	Cell Assay Reagents
(R)-Naproxen acyl-β-D-glucuronide ((R)-Naproxen-β-D-glucuronide) is a compound metabolite with anti-inflammatory activity. (R)-Naproxen acyl-β-D-glucuronide can serve as a sensitive fluorescent substrate for proglutamyl peptidase 1, which produces a blue reaction after cleavage.

HY-W777012

Acridinium C2 NHS ester	Cell Assay Reagents
Acridinium C2 NHS ester is a chemiluminescent label that is active for the development of protein and nucleic acid probes. Acridinium C2 NHS ester can be used in bioanalysis and diagnostics to provide highly sensitive detection solutions. Acridinium C2 NHS ester is widely used in medical research, especially in the monitoring and analysis of biomolecules.

HY-147087

YSK 05	Drug Delivery
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .

HY-157916

ARP Aldehyde reactive probe	Indicators
ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 ⁴ nucleotides) .

HY-157926

Nitroso-PSAP	Chelators
Nitroso-PSAP is a sensitive and specific chromogenic reagent for iron (Fe ²⁺), which is used for the colorimetric determination of iron in blood after mineralization with periodic acid. TNitroso-PSAP chelates with iron (Fe ²⁺) to produce a green complex (λmax=756 nm, Epsilon = 4.5 x 10 < sup > 4 < / sup > dm < sup > 3 < / sup > mol < sup > 1 < / sup > cm < sup > 1 < / sup >) .

HY-W750190

L-Arginine 7-amido-4-methylcoumarin dihydrochloride	Enzyme Substrates
L-Arginine 7-amido-4-methylcoumarin dihydrochloride is a special fluorescent substrate with the potential to be used for detecting cathepsin H activity. L-Arginine 7-amido-4-methylcoumarin dihydrochloride can be used to provide highly sensitive fluorescent signals for biological research. L-Arginine 7-amido-4-methylcoumarin dihydrochloride has important applications in enzyme activity analysis.

HY-W090065

Pyren-1-ylmethanamine hydrochloride

1-Pyrenemethylamine hydrochloride

Biochemical Assay Reagents

Pyren-1-ylmethanamine hydrochloride, Pyren-1-ylmethanamine hydrochloride is commonly used as a fluorescent probe in biochemistry and molecular biology to detect and study nucleic acids, proteins and other biomolecules, moreover, it has been used in analytical chemistry Among them, for the detection of heavy metals and other pollutants in environmental samples, the pyrene group in the molecule exhibits strong fluorescence properties, which makes it useful as a sensitive and selective detector in various applications.

HY-140677

mPEG-amine (MW 5000)

mPEG-NH2 (MW 5000)

Drug Delivery

mPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies .

HY-113066C

Guanosine 5'-diphosphate (sodium), 96% (HPLC)

2 Publications Verification

GDP (sodium), Type I, 96% (HPLC)

Gene Sequencing and Synthesis

Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-D0175

3-Aminopropyltriethoxysilane

1 Publications Verification

γ-Aminopropyltriethoxysilane; APTES

Biochemical Assay Reagents

3-Aminopropyltriethoxysilane (APTES) acts as a strong glue to immobilize biomolecules such as antibodies and enzymes to silicon and silicon derivatives such as silicon nitride (Si₃N₄)) on. 3-Aminopropyltriethoxysilane also acts as a spacer, providing biomolecules with more spatial freedom during immobilization for higher specific activity. 3-Aminopropyltriethoxysilane can form a more stable, sensitive, and highly biocompatible bioanalytical platform by immobilizing biomolecules onto some solid materials, electrode materials, nanomaterials, and nanocomposites .

HY-W040144

Bromocresol green

Indicators

Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells .

HY-W009022

Diantipyrylmethane	Indicators
Diantipyrylmethane is a chromogenic agent commonly used in spectrophotometry and extraction photometry for the determination of metals such as Au(III), Ti(IV), Ir, Fe(III), Mo, Nd, U(IV), Ir, Pt, and Re. Diantipyrylmethane is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W034953

Bathocuproine disulfonate disodium

Biochemical Assay Reagents

Bathocuproine disulfonate disodium (BCS) is an organic compound used as a highly sensitive colorimetric reagent for copper ions in biochemical and analytical applications. It has a bright yellow color and absorbs light at specific wavelengths, so it can be used to detect and quantify trace copper. In biochemical applications, BCS is commonly used to study the role of copper ions in various biological processes. Copper is an essential nutrient for many organisms, but it can also be toxic in high concentrations, so accurate measurement of copper levels is important to understand its impact on living systems. In terms of analysis, BCS is often used in environmental monitoring and water quality testing to detect copper pollution. It can detect copper even at very low concentrations, making it an invaluable tool for identifying potential sources of pollution and assessing the impact of industrial activities on aquatic ecosystems.

Cat. No.	Product Name	Target	Research Area

HY-158307

Z-Arg-Arg-βNA acetate	Cathepsin	Others
Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins .

HY-P1626

Acetyl tetrapeptide-15	Opioid Receptor	Neurological Disease
Acetyl tetrapeptide-15 is a synthetic peptide used in the cosmetics for sensitive skin. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway .

HY-P4319

Boc-Glu-Lys-Lys-AMC	Fluorescent Dye	Others
Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin .

HY-P2685

MeOSuc-Ala-Ala-Pro-Val-pNA	Fluorescent Dye	Others
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .

HY-137784

Boc-Val-Pro-Arg-AMC hydrochloride	Fluorescent Dye	Others
Boc-Val-Pro-Arg-AMC hydrochloride is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .

HY-P4489

Suc-AAPM-pNA	Peptides	Others
Suc-AAPM-pNA is a sensitive substrate for the determination of human pancreatic elastase activity .

HY-P5868

mHuwentoxin-IV	Sodium Channel	Neurological Disease
mHuwentoxin-IV is a naturally modified Huwentoxin-IV (HY-P1220). mHuwentoxin-IV inhibits tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels of dorsal root ganglion neurons with an IC₅₀ of 54.16 nM. mHuwentoxin-IV inhibition of tetrodotoxin-sensitive sodium channels is not reversed by strong depolarization voltages .

HY-P2656

β-Defensin-4 (human) hBD-4	Bacterial	Infection
β-Defensin-4 human is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity .

HY-P4326

Boc-Val-Pro-Arg-AMC	Fluorescent Dye	Others
Boc-Val-Pro-Arg-MCA is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .

HY-P3147

IYPTNGYTR	Drug Metabolite	Others
IYPTNGYTR, a deamidation-sensitive signature peptide, is a deamidation product of Trastuzumab. IYPTNGYTR can be used to monitor in vivo Trastuzumab metabolism .

HY-P3147A

IYPTNGYTR acetate	Drug Metabolite	Others
IYPTNGYTR acetate, a deamidation-sensitive signature peptide, is a deamidation product of Trastuzumab. IYPTNGYTR acetate can be used to monitor in vivo Trastuzumab metabolism .

HY-P4519

Ac-Lys(Ac)-D-Ala-D-Lactic acid	Carboxypeptidase	Others
Ac-Lys(Ac)-D-Ala-D-Lactic acid is a depsipeptide substrate for penicillin-sensitive D-alanine carboxypeptidases (DD-carboxypeptidases) .

HY-P5226

Palmitoyl tripeptide-8	Peptides	Inflammation/Immunology
Palmitoyl tripeptide-8 s a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient .

HY-P5423

GALA	Peptides	Others
GALA is a biological active peptide. (GALA, a pH-sensitive fusogenic peptide, is a promising method to accelerate this step in order to enhance the expression of the desired proteins.)

HY-P5899

Mambalgin-3	Sodium Channel	Neurological Disease
Mambalgin-3 is an acid-sensitive ion channel 1 (ASIC1) inhibitor. Mambalgin-3 can be used in the study of analgesia .

HY-P5405

dTAT-HA2 Transducible TAT-HA fusogenic peptide	Peptides	Others
dTAT-HA2 enhances TAT-Cre escape from macropinosomes. dTAT-HA2 is a transfusible, *pH-sensitive, fusogenic* peptide .

HY-P5423A

GALA TFA	Peptides	Others
GALA (TFA) is a biological active peptide (GALA, a pH-sensitive fusogenic peptide, is a promising method to accelerate this step in order to enhance the expression of the desired proteins.) .

HY-P1347

RETF-4NA	Biochemical Assay Reagents	Metabolic Disease
RETF-4NA, a chymase-specific substrate, is a sensitive and selective substrate for chymase when free or bound to α₂M .

HY-125576

Griselimycin	Bacterial	Others
Griselimycin is a compound with antituberculosis activity that exhibits good in vitro and in vivo activity against sensitive and resistant Mycobacterium tuberculosis, and its cyclohexyl derivative has high transformative potential.

HY-P1347A

RETF-4NA TFA	Peptides	Metabolic Disease
RETF-4NA TFA, a chymase-specific substrate, is a sensitive and selective substrate for chymase when free or bound to α₂M .

HY-P4360

Suc-Ala-Phe-Lys-AMC	Fluorescent Dye	Others
Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K .

HY-103048A

PD-1/PD-L1-IN 3 TFA	PD-1/PD-L1	Cancer
PD-1/PD-L1-IN 3 TFA, a macrocyclic peptide, is a potent and selective inhibitor of the PD-1/PD-L1 and CD80/PD-L1 interactions extracted from patent WO2014151634A1, compound No.1. PD-1/PD-L1-IN 3 TFA interferes with PD-L1 binding to PD-1 and CD80 by binding to PD-L1, with IC₅₀s of 5.60 nM and 7.04 nM, respectively. PD-1/PD-L1-IN 3 TFA can be used for the research of various diseases, including cancer and infectious diseases .

HY-P4310

Boc-Val-Leu-Lys-AMC	Ser/Thr Protease	Others
Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain .

HY-P10073

Calpain-1 substrate, fluorogenic	Fluorescent Dye	Others
Calpain-1 substrate, fluorogenic serves as a sensitive and specific substrate for calpain-1 that cleaves Tyr-Gly bond and results in enhanced fluorescence .(Ex/Em = 490 nm/518 nm)

HY-P5227

Acetyl hexapeptide-49	Interleukin Related	Inflammation/Immunology
Acetyl hexapeptide-49 is a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient .

HY-P4113

TAT-NSF700 Fusion Peptide	Peptides	Neurological Disease
TAT-NSF700 Fusion Peptide is a potent N-ethyl-maleimide-sensitive factor (NSF) inhibitor. TAT-NSF700 Fusion Peptide can readily permeate the cell membrane and interact with the intracellular organelle directly .

HY-P5184

Hainantoxin-IV HNTX-IV	Sodium Channel	Neurological Disease
Hainantoxin-IV is a specific antagonist of Sodium Channel, targeting to tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels. His28 and Lys32 are the key resiudes of Hainantoxin-IV for binding with target, while Hainantoxin-IV adopts an inhibitor cystine knot motif .

HY-P5250

Palmitoyl tripeptide-5	MMP	Others
Palmitoyl tripeptide-5 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .

HY-P4110

TAT-NSF222 Fusion Peptide	iGluR	Metabolic Disease Inflammation/Immunology
TAT-NSF222 Fusion Peptide is a fusion polypeptide with two domains, a TAT domain, which enters cells through macropinocytosis, and an NSF domain that inhibits N-ethylmaleimide-sensitive factor (NSF). TAT-NSF222 Fusion Peptide is an exocytosis inhibitor .

HY-P5863

Mambalgin-2 Mamb-2	Sodium Channel	Neurological Disease
Mambalgin-2 (Mamb-2) is an acid-sensitive ion channels (ASICs) inhibitor and a venom peptide. Mambalgin-2 can be obtained from the venom of the African black mamba. Mambalgin-2 can be used in the study of pain and neurological diseases .

HY-P5180

Hainantoxin-III	Sodium Channel	Neurological Disease
Jingzhaotoxin-V is a peptide that inhibits potassium currents in Xenopus laevis oocytes with an IC₅₀ value of 604.2 nM. Jingzhaotoxin-V also inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC₅₀ values of 27.6 and 30.2 nM, respectively .

HY-P5773

Jingzhaotoxin-34	Sodium Channel	Neurological Disease
Jingzhaotoxin-34, a 35-residue polypeptide, is a neurotoxin. Jingzhaotoxin-34 inhibits *tetrodotoxin-sensitive* (TTX-S) sodium currents (IC₅₀** of ~85 nM) while having no significant effects on tetrodotoxin-resistant (TTX-R) sodium currents on rat dorsal root ganglion neurons .

HY-P10742

CBX-12	Peptide-Drug Conjugates (PDCs) Topoisomerase	Cancer
CBX-12 is a PDC (peptide drug conjugate) that targets tumors in an antigen-independent manner and exhibits antitumor activity. CBX-12 consists of a pH-sensitive peptide (pHLIP), a self-immolating linker, and a topoisomerase 1 (TOP1) inhibitor Exatecan (HY-13631) .

HY-P3799

[Glp6] Substance P (6-11)	Neurokinin Receptor	Neurological Disease
[Glp6] Substance P (6-11) is an analogue of substance P (6-11). Substance P (6-11) stimulates [3H]-inositol monophosphate ([3H]-IP1) formation in rat urinary bladder by acting on the 'septide-sensitive' tachykinin receptors .

HY-P2213

GPLGIAGQ	MMP Apoptosis	Cancer
GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .

HY-P2213A

GPLGIAGQ TFA	MMP Apoptosis	Cancer
GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .

HY-P10765

DTS-108	Peptide-Drug Conjugates (PDCs) Topoisomerase	Cancer
DTS-108 is a prodrug of SN38 (HY-13704) (a Topoisomerase I inhibitor). DTS-108 is a conjugate generated by linking SN38 to a human oligopeptide via an esterase sensitive cross-linker. DTS-108 exhibits anti-tumor activity against colorectal, lung, and mammary cancer .

HY-P5771

Jingzhaotoxin-IX	Sodium Channel	Neurological Disease
Jingzhaotoxin-IX, a C-terminally amidated peptide composed of 35 amino acid residues, is a neurotoxin. Jingzhaotoxin-IX inhibits voltage-gated sodium channels (both tetrodotoxin-resistant and tetrodotoxin-sensitive isoforms) and Kv2.1 channel. Jingzhaotoxin-IX has no effect on delayed rectifier potassium channel Kv1.1, 1.2 and 1.3 .

HY-P4108

TAT-HA2 Fusion Peptide	Influenza Virus	Infection
TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide is a transactivator of transcription and hemaglutanin for endosomal release. TAT-HA2 Fusion Peptide enhances cellular uptake of macromolecules .

HY-P5916

VSTx-3 κ-Theraphotoxin-Gr4a; Kappa-TRTX-Gr4a; Voltage sensor toxin 3; Peptide F	Peptides Potassium Channel	Neurological Disease
VSTx-3 is a K_V channel blocker. VSTx-3 is demonstrated to be a potent, TTX-sensitive sodium channel blocker and especially, a potent blocker of NaV1.8 channels (IC₅₀ 0.19 μM for hNaV1.3, 0.43 μM for hNaV1.7 and 0.77 μM for hNaV1.8 channels).

HY-P3106

(Z-Ala-Ala-Ala-Ala)2Rh110 (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110	Fluorescent Dye	Others
(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.

HY-P5770

Jingzhaotoxin-V	Sodium Channel	Neurological Disease
Jingzhaotoxin-V, a 29-residue polypeptide, is derived from the venom of the spider Chilobrachys jingzhao. Jingzhaotoxin-V inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC₅₀ values of 27.6 nM and 30.2 nM, respectively. Jingzhaotoxin-V also inhibits Kv4.2 potassium currents expressed in Xenpus Laevis oocytes (IC₅₀ of 604.2 nM) .

HY-P1399

Pep2m, myristoylated Myr-Pep2m	PKC	Neurological Disease
Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, *N-ethylmaleimide-sensitive* factor/glutamate receptor subunit 2 (NSF/GluR2) interactions**. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .

HY-P3749

Mca-(ala7,lys(dnp)9)-bradykinin	Fluorescent Dye	Others
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .

HY-P1399A

Pep2m, myristoylated TFA Myr-Pep2m TFA	PKC	Neurological Disease
Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, *N-ethylmaleimide-sensitive* factor/glutamate receptor subunit 2 (NSF/GluR2) interactions**. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .

HY-123275A

H-D-Phe-Pip-Arg-pNA hydrochloride S-2238 hydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .

HY-123275

H-D-Phe-Pip-Arg-pNA S-2238	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .

HY-123275C

H-D-Phe-Pip-Arg-pNA dihydrochloride S-2238 dihydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .

HY-123275B

H-D-Phe-Pip-Arg-pNA acetate S-2238 acetate	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .

HY-P1205

MCH(human, mouse, rat) Melanin-concentrating hormone(human, mouse, rat)	MCHR1 (GPR24)	Neurological Disease
MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC₅₀ values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC₅₀ values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively .

Cat. No.	Product Name

HY-K2006

Sensitive ECL Kit 3 Publications Verification
Sensitive ECL Kit enables low picogram detection of antigen by oxidizing luminol in the presence of HRP and peroxide. This reaction produces a prolonged chemiluminescence which can be visualized on X-ray film or digital imaging systems.

HY-K0301

Cell Counting Kit-8 Maximum Cited Publications 2747 Publications Verification
Cell Counting Kit-8 (CCK-8) allows sensitive colorimetric assays for the determination of cell viability in cell proliferation and cytotoxicity assays.

HY-K1004

SYBR Green I Nucleic Acid Gel Stain 5+ Cited Publications
MCE SYBR Green I Nucleic Acid Gel Stain is one of the most sensitive stains available for detecting double-stranded DNA (dsDNA) in agarose and polyacrylamide gels.

HY-K1005

Ultra High Sensitivity ECL Kit 70+ Cited Publications
MCE Ultra High Sensitivity ECL Kit is an ultra-sensitive, luminol-based enhanced chemiluminescent substrate for detecting horseradish peroxidase (HRP) labeled antibodies on western blots.

HY-K1103

Coomassie Blue Fast Staining Solution (No Heating, 10×)
MCE Coomassie Blue Fast Staining Solution (No Heating, 10×) uses Coomassie Brilliant Blue G250 as the dye. It can be used for rapid, sensitive staining of protein gels in SDS-PAGE or Native-PAGE without contamination, or for detecting residual proteins on PAGE gels after Western Blot transfer.

Cat. No.	Product Name	Target	Research Area

HY-P99463

Batiraxcept AVB-S6-500	TAM Receptor	Cancer
Batiraxcept (AVB-S6-500) is a highly potent and specific AXL inhibitor, a recombinant fusion protein dimer containing the extracellular domain of human AXLM and human immunoglobulin G1 heavy chain (Fc). Batiraxcept binds to GAS6 and inhibits the interaction of GAS6 with AXL, thereby substantially reducing AXL signaled invasion and migration of highly metastatic cells in vitro and inhibiting metastatic disease in nonclinical models of aggressive human cancers. Batiraxcept is available for studies in advanced or metastatic clear cell renal cell carcinoma (ccRCC) and platinum sensitive recurrent ovarian cancer .

Species:	Human (13) Mouse (1)
Tag:	GFP (1) His (13) SUMO (1) Tag Free (1) Strep (2) GST (2) MBP (2) Flag (3)
Source:	HEK293 (4) E. coli Cell-free (1) Sf9 insect cells (1) P. pastoris (2) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source

HY-P71326

	SNAP-alpha Protein, Human (His) Alpha-Soluble NSF Attachment Protein; SNAP-Alpha; N-Ethylmaleimide-sensitive Factor Attachment Protein Alpha; NAPA; SNAPA	Human	E. coli
	SNAP-α proteins are critical in vesicle trafficking, mediating dynamic exchange between the endoplasmic reticulum and the Golgi apparatus. It cooperates with GNA12 to localize CDH5 to the plasma membrane. SNAP-alpha Protein, Human (His) is the recombinant human-derived SNAP-alpha protein, expressed by E. coli , with N-6*His labeled tag. The total length of SNAP-alpha Protein, Human (His) is 295 a.a., with molecular weight of 33-35 kDa.

HY-P702792

	CRIP1 Protein, Human (GST) CKBBP1; CKII beta binding protein 1; CKII beta-binding protein 1; Rbx 2; Rbx2; RBX2_HUMAN; Regulator of cullins 2; RING box protein 2; RING finger protein 7; RING-box protein 2; RNF 7; RNF7; ROC 2; ROC2; SAG; sensitive to apoptosis gene; sensitive to apoptosis gene protein; Zinc RING finger protein SAG	Human	E. coli
	CRIP1 Protein, Human (GST) is the recombinant human-derived CRIP1, expressed by E. coli , with N-GST labeled tag. The total length of CRIP1 Protein, Human (GST) is 77 a.a.,

HY-P702398

	OPN1LW Protein, Human (Cell-Free, His) Long-wave-sensitive opsin 1; Red cone photoreceptor pigment; Red-sensitive opsin; ROP	Human	E. coli Cell-free
	OPN1LW protein, crucial for vision, is a vital element of visual pigments responsible for light absorption. The pigments consist of opsin, forming a covalent bond with cis-retinal. This molecular mechanism is indispensable for perceiving light stimuli in vision. OPN1LW Protein, Human (Cell-Free, His) is the recombinant human-derived OPN1LW protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of OPN1LW Protein, Human (Cell-Free, His) is 364 a.a., with molecular weight of 43.4 kDa.

HY-P702029

	SLC29A1 Protein, Human (Sf9, His, MBP, FLAG) SLC29A1; Equilibrative nucleoside transporter 1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative NBMPR-sensitive nucleoside transporter; Nucleoside transporter; es-type; Solute carrier family 29 member 1	Human	Sf9 insect cells
	The SLC29A1 protein is an important uniporter that actively promotes the transport of nucleosides and nucleobases and maintains cellular homeostasis of essential compounds. As a Na(+)-independent transporter, SLC29A1 efficiently transports a series of nucleosides and nucleobases, including adenosine, guanosine, inosine, uridine, thymidine, cytidine, hypoxanthine, adenine, guanine, Thymine and uracil. SLC29A1 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC29A1 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC29A1 Protein, Human (Sf9, His, MBP, FLAG) is 455 a.a., .

HY-P701958

	PBP1A Protein, Mycobacterium tuberculosis ponA1; Penicillin-binding protein 1A; PBP-1A; Penicillin-binding protein 1; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive* transpeptidase; DD-transpeptidase	Others	E. coli
	PBP1A (penicillin-binding protein 1A) is involved in cell wall formation and plays a crucial role in the synthesis of cross-linked peptidoglycan from lipid intermediates. The enzyme has a bifunctional structure. The penicillin-insensitive transglycosylase N-terminal domain is responsible for the formation of linear glycan chains, and the penicillin-sensitive transpeptidase C-terminal domain promotes the cross-linking of peptide subunits. PBP1A Protein, Mycobacterium tuberculosis is the recombinant PBP1A protein, expressed by E. coli , with tag free. The total length of PBP1A Protein, Mycobacterium tuberculosis is 430 a.a., .

HY-P701959

	PBP1A Protein, Mycobacterium tuberculosis (His) ponA1; Penicillin-binding protein 1A; PBP-1A; Penicillin-binding protein 1; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive* transpeptidase; DD-transpeptidase	Others	E. coli
	PBP1A (penicillin-binding protein 1A) is involved in cell wall formation and plays a crucial role in the synthesis of cross-linked peptidoglycan from lipid intermediates. The enzyme has a bifunctional structure. The penicillin-insensitive transglycosylase N-terminal domain is responsible for the formation of linear glycan chains, and the penicillin-sensitive transpeptidase C-terminal domain promotes the cross-linking of peptide subunits. PBP1A Protein, Mycobacterium tuberculosis (His) is the recombinant PBP1A protein, expressed by E. coli , with N-6*His labeled tag. The total length of PBP1A Protein, Mycobacterium tuberculosis (His) is 430 a.a., .

HY-P701382

	TRPA1 Protein, Human (HEK293, His, MBP, FLAG) TRPA1; Transient receptor potential cation channel subfamily A member 1; Ankyrin-like with transmembrane domains protein 1; Transformation-sensitive protein p120; Wasabi receptor	Human	HEK293
	The TRPA1 protein is a receptor-activated nonselective cation channel that is critical for pain detection and may affect cold sensation, oxygen sensing, cough reflex, itch, and inner ear function. It responds to inflammatory mediators and irritants such as allyl thiocyanate (AITC), cinnamic aldehyde, diallyl disulfide (DADS), and acrolein. TRPA1 Protein, Human (HEK293, His, MBP, FLAG) is the recombinant human-derived TRPA1 protein, expressed by HEK293 , with N-10*His, N-MBP, C-Flag labeled tag. The total length of TRPA1 Protein, Human (HEK293, His, MBP, FLAG) is 1118 a.a. .

HY-P702022

	SLC12A2 Protein, Human (Sf9, His, StrepⅡ, FLAG) SLC12A2; Solute carrier family 12 member 2; Basolateral Na-K-Cl symporter; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2	Human	HEK293
	SLC12A2 Protein mediates electroneutral transport of chloride, potassium, and/or sodium ions across the membrane, crucial for regulating ionic balance and cell volume. SLC12A2 Protein, Human (HEK293, His, Strep, FLAG) is the recombinant human-derived SLC12A2 protein, expressed by HEK293 insect cells , with N-Strep, C-Flag, N-8*His labeled tag. The total length of SLC12A2 Protein, Human (HEK293, His, Strep, FLAG) is 1211 a.a., .

HY-P703077

	SLC12A2 Protein, Human (HEK293, His, StrepⅡ, GFP) SLC12A2; Solute carrier family 12 member 2; Basolateral Na-K-Cl symporter; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2	Human	HEK293
	SLC12A2 Protein mediates electroneutral transport of chloride, potassium, and/or sodium ions across the membrane, crucial for regulating ionic balance and cell volume. SLC12A2 Protein, Human (HEK293, His, Strep, GFP) is the recombinant human-derived SLC12A2 protein, expressed by HEK293 , with N-Strep, N-EGF, N-His labeled tag.

HY-P702791

	RNF7 Protein, Human (GST) CKBBP1; CKII beta binding protein 1; CKII beta-binding protein 1; Rbx 2; Rbx2; RBX2_HUMAN; Regulator of cullins 2; RING box protein 2; RING finger protein 7; RING-box protein 2; RNF 7; RNF7; ROC 2; ROC2; SAG; sensitive to apoptosis gene; sensitive to apoptosis gene protein; Zinc RING finger protein SAG	Human	E. coli
	RNF7 Protein, Human (GST) is the recombinant human-derived RNF7, expressed by E. coli , with N-GST labeled tag. ,

HY-P70065

	AOC3 Protein, Human (HEK293, His) rHuMembrane primary amine oxidase/AOC3, His; Membrane primary amine oxidase; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1; AOC3; VAP1	Human	HEK293
	As a cell adhesion molecule, AOC3 protein plays a key role in lymphocyte extravasation and recycling by promoting the binding of lymphocytes to peripheral lymph node vascular endothelial cells, independent of L-selectin. In addition to its role in cell adhesion, AOC3 exhibits semicarbazide-sensitive monoamine oxidase activity, contributing to its enzymatic function. AOC3 Protein, Human (HEK293, His) is the recombinant human-derived AOC3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of AOC3 Protein, Human (HEK293, His) is 736 a.a., with molecular weight of ~95 kDa.

HY-P702790

	RNF7 Protein, Human (P.pastoris, His) CKBBP1; CKII beta binding protein 1; CKII beta-binding protein 1; Rbx 2; Rbx2; RBX2_HUMAN; Regulator of cullins 2; RING box protein 2; RING finger protein 7; RING-box protein 2; RNF 7; RNF7; ROC 2; ROC2; SAG; sensitive to apoptosis gene; sensitive to apoptosis gene protein; Zinc RING finger protein SAG	Human	P. pastoris
	RNF7 Protein, Human (P.pastoris, His) is the recombinant human-derived RNF7, expressed by P. pastoris , with N-6*His labeled tag. ,

HY-P70335

	IMPA1 Protein, Human (His) rHuInositol monophosphatase 1/IMPA1, His; Inositol Monophosphatase 1; IMP 1; IMPase 1; Inositol-1(or 4)-Monophosphatase 1; Lithium-sensitive Myo-Inositol Monophosphatase A1; IMPA1; IMPA	Human	E. coli
	IMPA1 protein provides essential inositol for the synthesis of phosphatidylinositol and polyphosphate inositol. IMPA1 Protein, Human (His) is the recombinant human-derived IMPA1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702822

	YBX1 Protein, Mouse (P.pastoris, His) Ybx1; Msy-1; Msy1; Nsep1; Yb1; Y-box-binding protein 1; YB-1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Nuclease-sensitive element-binding protein 1; Y-box transcription factor	Mouse	P. pastoris
	YBX1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived YBX1, expressed by P. pastoris , with N-6*His labeled tag. ,

HY-P72166

	DBI Protein, Human (103a.a, His) ACBD1; ACBP; ACBP_HUMAN; Acyl CoA binding domain containing 1; Acyl CoA binding protein; Acyl Coenzyme A binding domain containing 1; Acyl coenzyme A binding protein; Acyl-CoA-binding protein; CCK RP; CCKRP; Cholecystokinin releasing peptide trypsin sensitive; DBI; Diazepam-binding inhibitor; Endozepine; EP; GABA receptor modulator; MGC70414	Human	E. coli
	DBI, a versatile protein, binds medium- and long-chain acyl-CoA esters, indicating a potential intracellular carrier role. It also displaces diazepam from the benzodiazepine recognition site on the GABA type A receptor. This dual functionality suggests DBI may act as a neuropeptide, modulating GABA receptor activity. Remarkably, DBI functions as a monomer in these interactions. DBI Protein, Human (103a.a, His) is the recombinant human-derived DBI protein, expressed by E. coli , with N-6*His labeled tag. The total length of DBI Protein, Human (103a.a, His) is 103 a.a., with molecular weight of ~14 kDa.

HY-P72109

	CACNA2D1 Protein, Human (His-SUMO) CA2D1_HUMAN; CACN A2; CACNA2; Cacna2d1; CACNL2A; Calcium channel L type alpha 2 polypeptide; Calcium channel voltage dependent alpha 2/delta subunit 1; CCHL2A; Dihydropyridine receptor alpha 2 subunit; Dihydropyridine sensitive L type calcium channel alpha 2/delta subunit; Dihydropyridine sensitive L type calcium channel subunits alpha 2/delta; L type calcium channel subunit alpha 2; MHS 3; MHS3; Voltage dependent calcium channel subunit alpha 2/delta 1; Voltage gated calcium channel subunit alpha 2/delta 1; Voltage-dependent calcium channel subunit delta-1; Voltage-gated calcium channel subunit alpha-2/delta-1	Human	E. coli
	The CACNA2D1 protein, particularly its α-2/δ subunit, plays a key role in regulating calcium current density and activation/deactivation kinetics of voltage-dependent calcium channels. It contributes to excitation-contraction coupling, coordinating cellular processes. CACNA2D1 Protein, Human (His-SUMO) is the recombinant human-derived CACNA2D1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of CACNA2D1 Protein, Human (His-SUMO) is 141 a.a., with molecular weight of ~32.3 kDa.

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Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
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Free Sample	Yes No
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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80464

	*Phospho-Hormone sensitive* lipase (Ser853) Antibody** Hormone sensitive lipase antibody; Hormone sensitive lipase testicular isoform antibody; Hormone-sensitive lipase antibody; HSL antibody; LHS; Lipase hormone sensitive antibody; LIPE antibody; LIPS_HUMAN antibody; Phospho-Hormonesensitivelipase(S853); PhosphoHormonesensitivelipase(S853)	WB, IHC-P	Human, Mouse, Rat
	Phospho-Hormone sensitive lipase (Ser853) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 117 kDa, targeting to Phospho-Hormone sensitive lipase (S853). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P81204

	Alpha-ENaC Antibody Alpha ENaC 2; Alpha ENaC; Alpha NaCH; Alpha-NaCH; Amiloride sensitive epithelial sodium channel alpha subunit; Amiloride sensitive sodium channel subunit alpha; Amiloride-sensitive sodium channel subunit alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; Epithelial Na+ channel subunit alpha; FLJ21883; Nonvoltage gated sodium channel 1 subunit alpha; Nonvoltage-gated sodium channel 1 subunit alpha; SCNEA; SCNN 1; SCNN1; SCNN1A; SCNNA_HUMAN; Sodium channel nonvoltage gated 1 alpha.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat
	Alpha-ENaC Antibody is an unconjugated, approximately 76 kDa, rabbit-derived, anti-Alpha-ENaC polyclonal antibody. Alpha-ENaC Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, pig, cow, horse, sheep background without labeling.

HY-P80936

	YB1 Antibody YBX1; NSEP1; YB1; Nuclease-sensitive element-binding protein 1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YB-	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	YB1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 36 kDa, targeting to YB1. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P82854

	*Phospho-Hormone Sensitive* Lipase (Ser855) Antibody (YA2599)** LIPE; Hormone-sensitive lipase; HSL	WB	Human
	Phospho-Hormone Sensitive Lipase (Ser855) Antibody (YA2599) is a biotin-conjugated non-conjugated IgG antibody, targeting Phospho-Hormone Sensitive Lipase (Ser855), with a predicted molecular weight of 117 kDa (observed band size: 83 kDa). Phospho-Hormone Sensitive Lipase (Ser855) Antibody (YA2599) can be used for WB experiment in human background.

HY-P83742

	SLC12A1 Antibody (YA3471) BSC1 antibody; Bumetanide sensitive sodium 3 antibody; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 antibody; Kidney specific Na K Cl symporter antibody; Kidney-specific Na-K-Cl symporter antibody; MGC48843 antibody; Na K 2Cl cotransporter antibody; NKCC2 antibody; potassiumchloride cotransporter 2 antibody; S12A1_HUMAN antibody; Slc12a1 antibody; sodium potassium chloride cotransporter 2 antibody; solute carrier family 12 (sodium/potassium/chloride transporters) antibody; Solute carrier family 12 member 1 antibody	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	SLC12A1 Antibody (YA3471) is a non-conjugated IgG antibody, targeting SLC12A1, with a predicted molecular weight of 121 kDa (observed band size: 150 kDa). SLC12A1 Antibody (YA3471) can be used for WB, IHC-P, IF-Cell, mIHC experiment in human, Mouse and Rat background.

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Free Sample	Yes No
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Cat. No.	Product Name		Classification

HY-B0216

Ethinylestradiol 2 Publications Verification Ethynyl estradiol; 17α-Ethynylestradiol		Alkynes
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers .

HY-130913

5-FAM-Alkyne		Alkynes Labeling and Fluorescence Imaging
5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP) . 5-FAM-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-119323

7-Azido-4-methylcoumarin		Azide Labeling and Fluorescence Imaging
7-Azido-4-methylcoumarin is a fluorescent hydrogen sulfide (H2S) probe. 7-Azido-4-methylcoumarin serves as a highly sensitive assay for cystathionine β-synthase activity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151711

Sulfo-Cy5.5 Azide		Labeling and Fluorescence Imaging Azide
Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-118411

5-Ethynyl-2'-deoxyuridine 15+ Cited Publications		Alkynes PROTAC Synthesis
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1593

BODIPY TMR-X alkyne		Alkynes Labeling and Fluorescence Imaging
BODIPY TMR-X alkyne, an orange-fluorescent dye, is an alkyne modified BODIPY TMR-X. BODIPY TMR-X alkyne can react with azides by the copper-catalyzed click reaction. BODIPY TMR-X alkyne is not sensitive to pH.

HY-151710

Sulfo-Cy3 Azide		Labeling and Fluorescence Imaging Azide
Sulfo-Cy3 Azide is a water-soluble fluorogenic dye containing an azide group, which enables Click Chemistry. Sulfo-Cy3 Azide can be used for the labeling of sensitive molecules such as proteins . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-142989

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine		Phospholipids
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs .

HY-139305

CL4H6		Cationic Lipids
CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .

HY-147087

YSK 05		Cationic Lipids
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .

HY-113066A

Guanosine 5'-diphosphate disodium salt 2 Publications Verification GDP disodium salt		Nucleotides and their Analogs
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-144025

DOBAQ		Cationic Lipids
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .

HY-W441021

DSPE-Pyrene		Phospholipids
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.

HY-113066

Guanosine 5'-diphosphate GDP		Nucleotides and their Analogs
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

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