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E. coli.

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Amino Acid Derivatives (3) Antibiotic (58) Antifolate (2) Apoptosis (7) Autophagy (7) Bacterial (242) Beta-lactamase (2) Biochemical Assay Reagents (13) Calcium Channel (2) COX (3) Dihydrofolate reductase (DHFR) (3) DNA/RNA Synthesis (11) Drug Derivative (1) Endogenous Metabolite (29) Fatty Acid Synthase (FASN) (1) Fluorescent Dye (9) Fungal (17) Gli (1) Glutathione Peroxidase (1) Glycosyltransferase (1) HIV (1) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (1) Isotope-Labeled Compounds (4) MAPKAPK2 (MK2) (1) Mitochondrial Metabolism (1) NF-κB (1) Nucleoside Antimetabolite/Analog (3) Oxidative Phosphorylation (1) PD-1/PD-L1 (1) Penicillin-binding protein (PBP) (1) Phosphodiesterase (PDE) (1) Phospholipase (1) Pyruvate Kinase (1) Renin (1) Smo (1) Toll-like Receptor (TLR) (7) Topoisomerase (9) Tyrosinase (1) β-glucuronidase (8)
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320

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109

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2854

Alanine dehydrogenase, expressed in E. coli	Endogenous Metabolite	Metabolic Disease
Alanine dehydrogenase, expressed in E. coli is a microbial enzyme that catalyzes a reversible conversion of L-alanine to pyruvate .

HY-D1056

*Lipopolysaccharides, from E. coli* O55:B5** Maximum Cited Publications 265 Publications Verification LPS	Toll-like Receptor (TLR)	Inflammation/Immunology Cancer
Lipopolysaccharides, from E. coli O55:B5 (LPS, from Escherichia coli (O55:B5)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O55:B5) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O55:B5 possess the typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activate TLR-4 in immune cells, exhibit high pyrogenicity, and demonstrate dose and serotype specificity. *Lipopolysaccharides, from E. coli* O55:B5 can be used to induce cellular inflammation and establish animal models related to inflammation** .

HY-157351

E.Coli Broth	Biochemical Assay Reagents	Others
E.Coli Broth is a selectively concentrated broth that can be used to isolate, detect or culture E. coli.

HY-NP025

E.coli Bacterial protein EPEC	Bacterial	Infection
E.coli Bacterial protein is a native protein that can be isolated from E.coli .

HY-170810

E.coli Gyrase B-IN-1	Bacterial	Infection
E.coli Gyrase B-IN-1 (Compound 10g) is a E.coli Gyrase B inhibitor with antibacterial activities. E.coli Gyrase B-IN-1 has potent inhibitory activity against E. coli, with a MIC value of 0.12 mM. E.coli Gyrase B-IN-1 is promising for research of antimicrobial agents .

HY-NP020

E.coli DH-5 alpha Bacterial protein E.coli DH-5 alpha protein	Bacterial	Others
E.coli DH-5 alpha Bacterial protein is a purified native protein from E.coli DH-5 alpha bacterial .

HY-E70412

Galactose 1-dehydrogenase, E.coli	Endogenous Metabolite	Metabolic Disease
Galactose 1-dehydrogenase, E.coli is a dehydrogenase expressed in E. coli. Galactose 1-dehydrogenase, E.coli catalyzes the oxidation of L-arabinose and D-galactose using NADP ⁺/NAD ⁺ as cofactors. Galactose 1-dehydrogenase, E.coli can be used in diagnostic tests to determine total galactose content and can also serve as a biocatalyst for producing galacturonate .

HY-P5089

*Enterotoxin STp (E. coli)*	Biochemical Assay Reagents	Infection
Enterotoxin STp (E. coli) is a heat-stable enterotoxin that can be used in vaccine research .

HY-D1056A5

*Lipopolysaccharides, from E. coli* K-235** LPS, from Escherichia coli (K-235)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from E. coli (Escherichia coli) K-235 are lipopolysaccharide endotoxins and TLR-4 activators derived from E. coli, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from E. coli K-235 exhibit a typical three-part structure: O-antigen (O-antigen), core oligosaccharide (core oligosaccharide), and lipid A (Lipid A). Lipopolysaccharides, from E. coli K-235 have a mitogenic effect on C57BL/10ScN spleen cells. Additionally, LPS purified using butanol and deoxycholic acid methods stimulates spleen cells in C57BL/10ScCR and C3H/HeJ mice .

HY-D1056A4

*Lipopolysaccharides, from E. coli* O128:B12** LPS, from Escherichia coli (O128:B12)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from E. coli O128:B12 (LPS, from Escherichia coli (O128:B12)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O128:B12) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O128:B12 possess the typical three-part structure: O-antigen, R3-type core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O128:B12 activate TLR-4 in immune cells, can be used to construct animal models of neonatal brain inflammation, and may influence preterm birth in neonates .

HY-D1056A2

*Lipopolysaccharides, from E. coli* O127:B8** LPS, from Escherichia coli (O127:B8)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from E. coli O127:B8 (LPS, from Escherichia coli (O127:B8)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O127:B8) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O127:B8 possess the typical three-part structure: O-antigen, R3-type core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O127:B8 activate TLR-4 in immune cells, can induce inflammatory responses and ileal contractility, and can be used to construct intestinal inflammation models .

HY-D1056A1

*Lipopolysaccharides, from E. coli* O111:B4** 1 Publications Verification LPS, from Escherichia coli (O111:B4)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O111:B4) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O111:B4 possess the typical three-part structure: O-antigen, R3-type core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O111:B4 activate TLR-4 in immune cells and can cause significant gastric diseases. *Lipopolysaccharides, from E. coli* O111:B4 can be used to induce cellular inflammation and establish animal models related to inflammation** .

HY-P5089A

*Enterotoxin STp (E. coli) TFA*	Biochemical Assay Reagents	Infection
Enterotoxin STp (E. coli) TFA is a heat-stable enterotoxin that can be used in vaccine research .

HY-D1056A3

*Lipopolysaccharides, from E. coli* O26:B6** LPS, from Escherichia coli (O26:B6)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from E. coli (Escherichia coli) O26:B6 are lipopolysaccharide endotoxins and TLR-4 activators derived from E. coli, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from E. coli O26:B6 exhibit a typical three-part structure: O-antigen (O-antigen), core oligosaccharide (core oligosaccharide), and lipid A (Lipid A), and can be recognized by the core-specific monoclonal antibody MAb J8-4C10. Lipopolysaccharides, from E. coli O26:B6 can promote an increase in pro-inflammatory cytokines in plasma, thereby triggering hypothalamic-pituitary-adrenal (HPA) activation and leading to adrenal oxidative damage. The pathogenic effects of Lipopolysaccharides, from E. coli O26:B6 can be blocked by PD149163 (HY-123434) .

HY-D1056F

*Biotin-Lipopolysaccharide, from E.coli* O111:B4** Biotin-LPS, from Escherichia coli (O111:B4)	Biochemical Assay Reagents	Others
Biotin-Lipopolysaccharide, from E.coli O111:B4 (Biotin-LPS, from Escherichia coli (O111:B4)) is a biotin-conjugated Lipopolysaccharide (LPS) (HY-D1056A1) that can be coupled with streptavidin protein. Biotin-Lipopolysaccharide, from E.coli O111:B4 can be used to identify Lipopolysaccharide ligands. Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O111:B4) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O111:B4 possess the typical three-part structure: O-antigen, R3-type core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O111:B4 activate TLR-4 in immune cells and can cause significant gastric diseases. Lipopolysaccharides, from E. coli O111:B4 can also induce M1-type polarization in mouse macrophages .

HY-P2869B

β1-4 Galactosidase, E. coli	Endogenous Metabolite	Metabolic Disease
β1-4 Galactosidase, E. coli is a highly specific exoglycosidase that catalyzes the hydrolysis of terminal, non-reducing β1-4 linked galactose residues from oligosaccharides .

HY-P2733

Glycerol-3-phosphate oxidase, E. coli GPO	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .

HY-114737

L-573655	Bacterial	Infection
L-573655 is a reversible inhibitor of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase with an IC₅₀ value of 8.5 μM. L-573655 possesses antibacterial activity against a wild-type strain of E. coli. with MIC values of 200-400 μg/mL .

HY-E70284

Keratanase II,bacillus circulans,expressed in E.coli	Biochemical Assay Reagents	Others
Keratanase II,bacillus circulans,expressed in E.coli has transglycosylation activity. Keratanase II,bacillus circulans,expressed in E.coli efficiently catalyzes the transglycosylation of α(2→3)-sialylated 6,6′-di-sulfo-LacNAc with two kinds of glycosyl acceptors, 6-sulfo-Lewis X and 6,6'-di-sulfo-LacNAc derivatives, providing Sialyl sulfo-hexasaccharide and Sialyl sulfo-pentasaccharide .

HY-P2869

β-Galactosidase, E. coli EC 3.2.1.23; GAL	Endogenous Metabolite	Others
β-Galactosidase (EC 3.2.1.23) is a glycoside hydrolase that hydrolyzes the β-glycosidic bonds formed between galactose and its organic moieties. In E.coli, the lacZ gene is the structural gene of β-galactosidase, which can be used as part of the induction system lac operon. β-Galactosidase can hydrolyze lactose to form glucose and galactose, and enter glycolysis; it can also catalyze the transgalactosylation of lactose into allolactose; allolactose can be cracked into monosaccharides .

HY-P2834

Penicillin amidase, E. coli PGA	Biochemical Assay Reagents	Infection Cancer
Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics .

HY-153771

Du011	Bacterial	Infection
Du011 is an E. coli polysaccharide capsule biogenesis inhibitor that targets MprA. Du011 can be used in research against E. coli infection .

HY-155048

BDM91270	Bacterial	Infection
BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC₉₀ of 0.6 μM for wild-type E. coli AcrB. BDM91270 can be used in the study of Escherichia coli drug resistance .

HY-E70414

DNase B, Escherichia coli	Others	Others
DNase B, Escherichia coli is an enzyme that specializes in the degradation of DNA and can be extracted from E.coli .

HY-133154

Carboxyaminoimidazole ribotide 2 Publications Verification CAIR; 4-Carboxy-AIR	Endogenous Metabolite	Infection
Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine .

HY-148197

Glutathionylspermidine	Endogenous Metabolite	Others
Glutathionylspermidine is a peptide and a metabolite of E. coli .

HY-Y0367

Maleic Acid 1 Publications Verification	Endogenous Metabolite Bacterial	Infection
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and *L. monocytogenes*.

HY-144701

SABA1	Antibiotic Bacterial	Infection Inflammation/Immunology
SABA1 possesses antibacterial properties against Pseudomonas aeruginosa and Escherichia coli, with an IC₅₀ of 4.0 µM against E. coli ACC .

HY-N14359

Megovalicin B	Bacterial	Infection
Megovalicin B has the effect against subtilis and E.coli .

HY-P1940

Maculosin Cyclo(Tyr-Pro)	Endogenous Metabolite Bacterial Fungal	Infection Cancer
Maculosin (Cyclo (Tyr-Pro)) is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication. Maculosin also acts as a signaling molecule regulating virulence gene expression. Maculosin shows antimicrobial, antifungal, antioxidant and anti-cancer properties .Maculosin (Cyclo (Tyr-Pro)) is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication. Maculosin also acts as a signaling molecule regulating virulence gene expression. Maculosin shows antimicrobial, antifungal, antioxidant and anti-cancer properties .

HY-P1940R

Maculosin (Standard)	Endogenous Metabolite Bacterial Fungal	Infection Cancer
Complanatuside (Standard) is the analytical standard of Complanatuside. This product is intended for research and analytical applications. Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

HY-E70207

dam Methyltransferase	Bacterial DNA/RNA Synthesis	Metabolic Disease
dam Methyltransferase plays a role in the control of DNA replication in E. coli .

HY-N14263

Kirrothricin	Bacterial	Infection
Kirrothricin has antibacterial action, but no activity to subtilis, E.coli and fungi .

HY-162884

β-Glucuronidase-IN-4	β-glucuronidase	Infection
EcGUS-IN-1 (Compound E-9) is a non-competitive β-glucuronidase inhibitor, with an IC₅₀ of 2.68 μM and a K_i value of 1.64 μM. EcGUS-IN-1 can improve gastrointestinal adverse events (GIAE) caused by Escherichia coli infection by inhibiting E. coli β-glucuronidase activity .

HY-156859

NSC309401 dihydrochloride	Bacterial	Inflammation/Immunology
NSC309401 is an inhibitor of E. coli DHFR (IC₅₀: 189 nM, K_D: 14.57 nM) .

HY-156859A

NSC309401	Bacterial	Infection
NSC309401 is an inhibitor of E. coli DHFR (IC₅₀: 189 nM, K_D: 14.57 nM) .

HY-P5720

Peptide 5e	Bacterial	Infection
Peptide 5e is an antimicrobial peptide. Peptide 5e inhibits E. coli, S. aureus, and C. albicans with MIC values of 30, 5, 25 μg/mL respectively .

HY-N8300

Rupesin E	Bacterial	Infection
Rupesin E is a natural product that can be isolated from Patrinia rupestris. Rupesin E has significant antibacterial activity against Escherichia coli .

HY-136861

Antibacterial agent 192	Bacterial	Infection
Antibacterial agent 192 is an antibacterial agent that can disrupt iron homeostasis in E. coli .

HY-N14132

Cyclothialidine E	DNA/RNA Synthesis	Infection
Cyclothialidine E inhibits escherichia coli DNA helicases with an IC₅₀ of 0.7 μM .

HY-N2594

Isoforsythiaside	Bacterial	Infection
Isoforsythiaside is an antioxidant and antibacterial phenylethanoid glycoside with MICs of 40.83, 40.83, and 81.66 μg/mL for Escherichia coli(E. coli), Pseudomonas aeruginosa(PAO), and Staphylococcus aureus (SA), respectively .

HY-144387

Antibacterial agent 71	Antibiotic Bacterial	Infection Inflammation/Immunology
ient S. Tm and hyperpermeable Escherichia coli. The potencies against WT strains of E. coli, Acinetobacter baumannii, and Burkholderia cenocepacia are also improved considerably (up to >128-fold) with the outer-membrane permeabi

HY-111643

6-Amino-5-azacytidine	Bacterial	Infection
6-Amino-5-azacytidine inhibits the growth of bacteria E. coli .

HY-139982

OX11	Bacterial	Infection
OX11 is a selective inhibitor of S. pneumoniae, P. aeruginosa, and E. coli bacterial strains .

HY-P5596

Combi-2	Bacterial	Infection
Combi-2 is an antimicrobial peptide against S.aureus, S.sanguis and E.coli .

HY-P5566

GLK-19	Bacterial	Infection
GLK-19 is an antimicrobial peptide, and is active against E. coli (MIC: 10 μM) .

HY-Z15868

5-Hydroxycytidine	Nucleoside Antimetabolite/Analog	Infection
5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli .

HY-P5753A

JB-95 acetate	Bacterial	Infection
JB-95 acetate, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 acetate can selectively disrupt the outer membrane but not the inner membrane of E. coli .

HY-146400

Antibacterial agent 97	Bacterial	Infection
Antibacterial agent 97 (hit compound) is a potent antibacterial agent. Antibacterial agent 97 shows antibacterial activities with MIC of 16 and 16 µg/mL for Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), respectively .

HY-P5753

JB-95	Bacterial	Infection
JB-95, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 can selectively disrupt the outer membrane but not the inner membrane of E. coli .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D1056

*Lipopolysaccharides, from E. coli* O55:B5** Maximum Cited Publications 265 Publications Verification LPS	Structural Classification Polysaccharides Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Saccharides	Toll-like Receptor (TLR)
Lipopolysaccharides, from E. coli O55:B5 (LPS, from Escherichia coli (O55:B5)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O55:B5) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O55:B5 possess the typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activate TLR-4 in immune cells, exhibit high pyrogenicity, and demonstrate dose and serotype specificity. *Lipopolysaccharides, from E. coli* O55:B5 can be used to induce cellular inflammation and establish animal models related to inflammation** .

HY-133154

Carboxyaminoimidazole ribotide 2 Publications Verification CAIR; 4-Carboxy-AIR	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine .

HY-Y0367

Maleic Acid 1 Publications Verification	Infection Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite Disease Research Fields	Endogenous Metabolite Bacterial
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and *L. monocytogenes*.

HY-P1940

Maculosin Cyclo(Tyr-Pro)	Alkaloids Monophenols Microorganisms Pyrrole Alkaloids Source classification Phenols Disease Research Fields Cancer	Endogenous Metabolite Bacterial Fungal
Maculosin (Cyclo (Tyr-Pro)) is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication. Maculosin also acts as a signaling molecule regulating virulence gene expression. Maculosin shows antimicrobial, antifungal, antioxidant and anti-cancer properties .Maculosin (Cyclo (Tyr-Pro)) is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication. Maculosin also acts as a signaling molecule regulating virulence gene expression. Maculosin shows antimicrobial, antifungal, antioxidant and anti-cancer properties .

HY-148197

Glutathionylspermidine	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glutathionylspermidine is a peptide and a metabolite of E. coli .

HY-N14359

Megovalicin B	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Bacterial
Megovalicin B has the effect against subtilis and E.coli .

HY-P1940R

Maculosin (Standard)	Alkaloids Monophenols Microorganisms Pyrrole Alkaloids Source classification Phenols	Endogenous Metabolite Bacterial Fungal
Complanatuside (Standard) is the analytical standard of Complanatuside. This product is intended for research and analytical applications. Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

HY-N14263

Kirrothricin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Kirrothricin has antibacterial action, but no activity to subtilis, E.coli and fungi .

HY-N8300

Rupesin E	Structural Classification Caprifoliaceae Iridoids Terpenoids Source classification Plants Patrinia rupestris (Pall.) Juss.	Bacterial
Rupesin E is a natural product that can be isolated from Patrinia rupestris. Rupesin E has significant antibacterial activity against Escherichia coli .

HY-N14132

Cyclothialidine E	Structural Classification Microorganisms Source classification Phenols Polyphenols	DNA/RNA Synthesis
Cyclothialidine E inhibits escherichia coli DNA helicases with an IC₅₀ of 0.7 μM .

HY-N2594

Isoforsythiaside	Infection Structural Classification Oleaceae Classification of Application Fields Simple Phenylpropanols Source classification Phenols Polyphenols Phenylpropanoids Forsythia suspensa (Thunb.) Vahl Plants Disease Research Fields	Bacterial
Isoforsythiaside is an antioxidant and antibacterial phenylethanoid glycoside with MICs of 40.83, 40.83, and 81.66 μg/mL for Escherichia coli(E. coli), Pseudomonas aeruginosa(PAO), and Staphylococcus aureus (SA), respectively .

HY-N12320

Majoranaquinone	Quinones Structural Classification Labiatae Source classification Plants Naphthalene Quinones Baccharis sarothroides A.Gray	Antibiotic
Majoranaquinone exhibits a high antibacterial effect against 4 Staphylococcus, 1 Moraxella, and 1 Enterococcus strains. Majoranaquinone shows substantial efflux pump inhibitory activity in Escherichia coliATCC 25922 strain. Majoranaquinone is found to be an effective biofilm formation inhibitor on E.coli, ATCC 25922 and E. coli K-12 AG100 bacteria .

HY-N7322

Swietemahalactone	Structural Classification Natural Products Source classification Plants Swietenia mahagoni (L.) Jacq. Meliaceae	Bacterial
Swietemahalactone is a natural compound isolated from Swietenia mahagoni. Swietemahalactone exhibits antibacterial activity aganist E. coli .

HY-N14360

Megovalicin H	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Bacterial
Megovalicin H has an effect against subtilis and E.coli, and it also has the effect against Pseudomonas aeruginosa .

HY-N11554

(-)-Codonopsine	Structural Classification Alkaloids Pyrrole Alkaloids Source classification Campanulaceae Codonopsis pilosula Plants	Bacterial
(-)-Codonopsine is an alkaloid that can be found in Codonopsis clematidea. It has antibacterial and hypotensive activities. The MIC value of (-)-Codonopsine against Escherichia coli (E. coli) is 64 μg/mL. (-)-Codonopsine is expected to be used in the research of anti-infection and cardiovascular fields .

HY-N13884

Amythiamicin D	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Amythiamicin D is a thiopeptide antibiotic that inhibits the growth of many Gram-positive bacteria, but not Gram-negative bacteria such as E.coli .

HY-N14829

Naphthoquinomycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Fungal
Naphthoquinomycin A is an Ansa antibiotic with anti-Gram-positive bacteria and fungi activity, and can inhibit the synthesis of E. coli fatty acids .

HY-113270

Actinine γ-Butyrobetaine; Deoxycarnitine	Structural Classification Natural Products Microorganisms Marine algae Source classification Marine natural products Endogenous metabolite	Endogenous Metabolite
Actinine (γ-Butyrobetaine) is an amino acid betaine aminobutyric acid zwitterion. Actinine acts as both a human metabolite and a metabolite of E. coli .

HY-N3651

Curzerenone 1 Publications Verification	Infection Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Source classification Curcuma phaeocaulis Valeton Plants Disease Research Fields Zingiberaceae	Bacterial
Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli .

HY-165154

Cyclamidomycin Desdanine; Pyracrimycin A	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Fungal Pyruvate Kinase Oxidative Phosphorylation
Cyclamidomycin (Desdanine) is an acrylamide antibiotic with antibacterial activity. Cyclamidomycin inhibits nucleoside diphosphate kinase and pyruvate kinase (in E. coli) and oxidative phosphorylation in rat liver mitochondria. Cyclamidomycin is active against S. aureus, M. flavus, S. lutea, B. subtilis, E. coli, S. flexneri, S. typhosa, P. vulgaris, and K. pneumoniae (MICs=3.12-25 mg/ml) .

HY-N14833

Naphthoquinomycin B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Fungal
Naphthoquinomycin B is an Ansa antibiotic with anti-Gram-positive bacteria and fungi activity, and can inhibit the synthesis of E. coli fatty acids .

HY-N1312

Sinapaldehyde	Infection Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields	Bacterial
Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μg/mL .

HY-N5127

Nonacosane	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	Bacterial
Nonacosane, isolated from Baphia massaiensis, exhibits weak activities against E. coli, B. subtilis, P. aeruginosa and S. aureus .

HY-N9477

Betulinic aldehyde oxime Betulin-28-oxime	Triterpenes Structural Classification Terpenoids Betula platyphylla Sukaczev Source classification Plants Betulaceae	Drug Derivative Bacterial
Betulinic aldehyde oxime (Compound 31) is a betulin (HY-N0083) derivative that has antimicrobial properties against E. aerogenes, E. coli, E. faecalis, P. aeruginosa, S. aureus, and C. albicans. Betulinic aldehyde oxime displays cytotoxicity towards hepatocytes, with an IC₅₀ of 25 μM .

HY-154871

α-D-Glucosamine 1-phosphate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
α-D-Glucosamine 1-phosphate is an E.coli metabolite. α-D-Glucosamine 1-phosphate is one of the precursors of peptidoglycan synthesis .

HY-N8515B

UDP-3-O-acyl-GlcNAc diammonium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc diammonium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N6738

Bafilomycin B1	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Fungal Antibiotic
Bafilomycin B1 is a macrolide antibiotic isolated from Streptomyces sp, inhibits Gram-positive bacteria and fungi, and acts as an inhibitor of K ⁺-dependent ATPase of E. coli .

HY-N3837

Epitaraxerol Isotaraxerol; 3α-Taraxerol	Triterpenes Structural Classification Excoecaria agallocha L. Terpenoids Source classification Euphorbiaceae Plants	Bacterial
Epitaraxerol (compound 6) is a natural product isolated from the leaves of E. neriifolia. Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis* .*

HY-130281

Ianthelliformisamine B diTFA	Structural Classification Natural Products Source classification Marine natural products Sponge	Bacterial
Ianthelliformisamine B diTFA is a bromotyrosine-derived antibacterial agent. Ianthelliformisamine B diTFA is against E. coli and S. aureus strains with MICs of 14.5 μM and 144.7 μM .

HY-N5127R

Nonacosane (Standard)	Structural Classification Natural Products other families Source classification Plants	Bacterial
Nonacosane (Standard) is the analytical standard of Nonacosane. This product is intended for research and analytical applications. Nonacosane, isolated from Baphia massaiensis, exhibits weak activities against E. coli, B. subtilis, P. aeruginosa and S. aureus .

HY-113054

DL-Glyceraldehyde 3-phosphate	Infection Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Acyltransferase Bacterial Endogenous Metabolite
DL-Glyceraldehyde 3-phosphate is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. DL-Glyceraldehyde 3-phosphate is a potent inhibitor of the growth of E. coli. DL-Glyceraldehyde 3-phosphate is a competitive inhibitor of the acyltransferase .

HY-N10087

Angustifoline	Structural Classification Alkaloids Leguminosae Lupinus angustifolius L. Plants	Bacterial
Angustifoline, an alkaloid, can be isolated from Lupinus angustifolius L. alkaloid extract. Angustifoline exhibits antimicrobial activity. Angustifoline could have bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis .

HY-N10087A

Angustifoline hydrochloride	Structural Classification Alkaloids Leguminosae Source classification Lupinus angustifolius L. Plants	Bacterial
Angustifoline hydrochloride, an alkaloid, can be isolated from Lupinus angustifolius L. alkaloid extract. Angustifoline hydrochloride exhibits antimicrobial activity. Angustifoline hydrochloride could have bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis .

HY-141465

3-Hydroxybutyryl-CoA	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
3-Hydroxybutyryl-CoA is a metabolite which can be found in mouse or E.coli, et al. 3-Hydroxybutyryl-CoA has a 3-hydroxybutanoyl as the S-acyl component, and is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan .

HY-W007972R

Methyl 3-methoxyacrylate (Standard)	Structural Classification Natural Products Microorganisms Source classification	Others
Anilazine (Standard) is the analytical standard of Anilazine. This product is intended for research and analytical applications. Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity .

HY-N1079

Vitexilactone	Structural Classification Terpenoids Verbenaceae Diterpenoids Plants Vitex negundo Linn.	Bacterial Apoptosis
Vitexilactone is a diterpenoid that can be isolated from the leaves of Vitex negundo L. Vitexilactone shows antimicrobial activity towards E. coli. Vitexilactone induces cell apoptosis and inhibits cell cycle of cancer cells. Vitexilactone can be used for the research of cancer .

HY-126634

Lyngbyatoxin B	Structural Classification Natural Products other families Source classification Plants Lyngbya majuscule	Others
Lyngbyatoxin B is a complex compound in a versatile biosynthetic pathway from the marine cyanobacterium Moorea producens. By heterologously expressing the lyngbyatoxin biosynthetic pathway in Escherichia coli, lyngbyatoxin A (25.6 mg/L) and its precursor indolactam-V (150 mg/L) were successfully produced. This approach confirmed the biosynthetic route of lyngbyatoxin and laid a chemical foundation for future pathway engineering. In addition, the successful production of lyngbyatoxin A in E. coli opens the possibility for heterologous expression and characterization of other cyanobacterial natural products.

HY-N7224

N-Formylfortimicin A SF-1854	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial Antibiotic
N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases .

HY-N14342

Manumycin E	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Manumycin E has anti-Gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-Gram-negative bacteria, and has no effect on fungi. Manumycin E inhibits RAS Faraday base transfer and has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC₅₀ is 15.6 μg/mL) .

HY-N8515

UDP-3-O-acyl-GlcNAc UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine	Structural Classification Natural Products Microorganisms Source classification	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N14627

Liposidomycin A	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Liposidomycin A has antibacterial effect, but the antibacterial activity is weak. Liposidomycin A has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). Liposidomycin A has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of E.coli with an IC₅₀ of 0.03 μg/mL .

HY-N8515C

UDP-3-O-acyl-GlcNAc disodium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine disodium	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) disodium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-W585865

UDP-3-O-acyl-GlcNAc Tris UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) Tris is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N1654

2',3'-Dehydrosalannol	Infection Natural Products Classification of Application Fields Source classification Azadirachta indica A. Juss. Plants Meliaceae Disease Research Fields	Bacterial
2',3'-Dehydrosalannol is a potent antibacterial agent. 2',3'-Dehydrosalannol shows antibacterial activity against K. pneumonia ATCC 13883, P. aeruginosa ATCC 27853, S. aureus ATCC 25922, E. coli ATCC 11775, and E. faecalis ATCC 10541, with MIC values of 0.78, 1.56, 1.56, 6.25, and 25 μg/mL, respectively .

HY-B0117

Tigecycline 25+ Cited Publications GAR-936	Microorganisms Source classification	Bacterial Autophagy Antibiotic
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL . MIC₅₀ and MIC₉₀ are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively .

HY-P5683

Maximin 45	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 45 is an antimicrobial peptide. Maximin 41 has antibacterial activity against S. aureus, E. coli, B. subtilis (MIC: 4.7, 9.4, 75 μg/mL). Maximin 45 has hemolytic activities against human and rabbit red cells .

HY-N14629

Liposidomycin C	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Liposidomycin C has antibacterial effect, but the antibacterial activity is weak. Liposidomycin C has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). Liposidomycin C has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of E.coli with an IC₅₀ of 0.03 μg/mL .

HY-N14628

Liposidomycin B	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Liposidomycin B has antibacterial effect, but the antibacterial activity is weak. Liposidomycin B has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). Liposidomycin B has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of E.coli with an IC₅₀ of 0.03 μg/mL .

HY-113245

3-Indolyl-β-D-glucuronide	Structural Classification Alkaloids Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Indole Alkaloids	Endogenous Metabolite
3-Indolyl-β-D-glucuronide, a chromogenic substrate for β-D-glucuronidase, employs in the detection and enumeration of E. coli, yielding a blue precipitate upon cleavage. 3-Indolyl-β-D-glucuronide in? patients' plasma act as a new indicator of renal failure .

HY-N8060

Orotidine 5′-monophosphate Orotidine monophosphate; Orotidylic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of?uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase .

Cat. No.	Product Name	Chemical Structure

HY-Y0367S

Maleic Acid-d2
Maleic Acid-d₂ is the deuterium labeled Maleic Acid[1]. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes[2][3].

HY-B0117S

Tigecycline-d9
Tigecycline-d₉ is deuterium labeled Tigecycline. Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL[1]. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively[2].

HY-W653962

Triclosan-13C6

Triclosan- ¹³C₆ is ¹³C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-118827S

Vedaprofen-d3
Vedaprofen-d₃ is the deuterium labeled Vedaprofen. Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition [1]. Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC50 of 222 μM[2].

HY-10581AS

Gatifloxacin-d3 hydrochloride

Gatifloxacin-d₃ (hydrochloride) is the deuterium labeled Gatifloxacin (hydrochloride). Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.

HY-W747491

Triclosan-13C12

Triclosan- ¹³C₁₂ is ¹³C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

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