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Results for "

NHS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (3) ADC Linker (136) Apoptosis (1) Autophagy (1) Biochemical Assay Reagents (122) DNA Stain (4) DNA/RNA Synthesis (1) Drug Derivative (1) Drug Intermediate (4) Drug-Linker Conjugates for ADC (8) E3 Ligase Ligand-Linker Conjugates (5) EGFR (1) Fluorescent Dye (172) Isotope-Labeled Compounds (3) Kinesin (1) Ligands for E3 Ligase (1) Liposome (16) LYTACs (1) Microtubule/Tubulin (3) Peptide-Drug Conjugates (PDCs) (1) PROTAC Linkers (244) PSMA (2) Radionuclide-Drug Conjugates (RDCs) (4) Reactive Oxygen Species (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (375) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (8) Metabolic Disease (2) Neurological Disease (1)
Click Chemistry:	ADC Synthesis (52) TCO (19) Labeling and Fluorescence Imaging (1) DBCO (28) PROTAC Synthesis (66) BCN (11) Azide (43) Tetrazine (22) Alkynes (17)
Oligonucleotides:	Pegylated Lipids (8) Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Phospholipids (4) Human Pre-designed siRNA Sets (1) Polymers (6) siRNAs (3)

704

Inhibitors & Agonists

165

Fluorescent Dye

Biochemical Assay Reagents

MCE Kits

Inhibitory Antibodies

Isotope-Labeled Compounds

140

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136304

**NHS-PEG1-SS-PEG1-NHS**	Biochemical Assay Reagents	Cardiovascular Disease Metabolic Disease Cancer
NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecule. NHS-PEG1-SS-PEG1-NHS can be used in proteins liposomes or nanoparticles .

HY-136133

**NHS-PEG2-SS-PEG2-NHS**	ADC Linker	Cancer
NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-D0802

Biotin NHS 10+ Cited Publications Biotin N-hydroxysuccinimide ester; NHS-Biotin	Fluorescent Dye	Others
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.

HY-147117

NHS-SS-Ac	Biochemical Assay Reagents	Others
NHS-SS-Ac is an amine-reactive product synthesized from acetic acid .

HY-140129

NHS-SS-biotin	ADC Linker	Cancer
NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-139326

NHS-MMAF	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
NHS-MMAF is a modified MMAF extracted from patent WO2012143499, intermediat 219. MMAF is a potent tubulin polymerization inhibitor and is used as a antitumor agent

HY-W615173

**NHS ester-C2-NHCO-C2-NHS**	Biochemical Assay Reagents	Others
NHS ester-C2-NHCO-C2-NHS is a heterobifunctional PEG linker, featuring a terminal NHS ester that can be used to label amine compounds and maleimide group for reactions with thiol groups.

HY-D0167

NHS-5(6)Carboxyrhodamine	Fluorescent Dye	Others
NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .

HY-W250735

NHS-PEG4-biotinidase resistant biotin	Biochemical Assay Reagents	Others
NHS-PEG4-biotinidase resistant biotin is a biotinylation reagent with a terminal NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

HY-RS09290

NHS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NHS Human Pre-designed siRNA Set A contains three designed siRNAs for NHS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NHS Human Pre-designed siRNA Set A NHS Human Pre-designed siRNA Set A

HY-RS22963

Nhs Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nhs Rat Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nhs Rat Pre-designed siRNA Set A Nhs Rat Pre-designed siRNA Set A

HY-RS16532

Nhs Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nhs Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nhs Mouse Pre-designed siRNA Set A Nhs Mouse Pre-designed siRNA Set A

HY-145714

NHS-NH-(diethylamino)ethyl benzoate	Biochemical Assay Reagents	Others
NHS-NH-(diethylamino)ethyl benzoate is a compound that can be used for N-glycan labeling .

HY-139325

NHS-Modified MMAF	Drug-Linker Conjugates for ADC	Others
NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) .

HY-W190737

NHS-S-S-dPEG4-biotin (cleavable)	Biochemical Assay Reagents
NHS-SS-dPEG4-biotin (cleavable) is a biodegradable crosslinker with efficient bioconjugation activity. NHS-SS-dPEG4-biotin (cleavable) can effectively connect biomolecules, optimize the efficiency of biolabeling, and be used in targeted compound delivery systems. NHS-SS-dPEG4-biotin (cleavable) can also play an important role in protein engineering and fluorescence imaging.

HY-139325A

NHS-Modified MMAF TFA	Drug-Linker Conjugates for ADC	Cancer
NHS-Modified MMAF (intermediat 210) TFA is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) .

HY-138509

NHS ester-PEG13-COOH	PROTAC Linkers	Cancer
NHS ester-PEG13-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-138511

NHS ester-PEG7-COOH	PROTAC Linkers	Cancer
NHS ester-PEG7-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-160719

NHS-activated 2-octynoic acid-BSA	Peptide-Drug Conjugates (PDCs)	Inflammation/Immunology
NHS-activated 2-octynoic acid-BSA is an immunogen used to establish a murine model of primary biliary cholangitis (PBC). NHS-activated 2-octynoic acid-BSA works in conjunction with Complete Freund's Adjuvant (HY-153808) to stimulate the body's immune system, causing the immune system to recognize it as a foreign antigen and trigger an immune response against autologous biliary epithelial cells. This leads to the production of anti-PDC-E2 antibodies, resulting in bile duct damage and inflammation. NHS-activated 2-octynoic acid-BSA is promising for research of primary biliary cholangitis .

HY-138522

NHS-bis-PEG2-amide-Mal	PROTAC Linkers	Cancer
NHS-bis-PEG2-amide-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-148657

Aminopterin N-hydroxysuccinimide ester NHS-Methotrexate	Others	Inflammation/Immunology Cancer
Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible Methotrexate (HY-14519) influx carrier inhibitor. Aminopterin N-hydroxysuccinimide ester can be used for the research of rheumatoid arthritis and a number of cancers (such as acute lymphoblastic leukemia) .

HY-157338

NHS-Ala-Ala-Asn-active metabolite	ADC Linker Kinesin	Cancer
NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor .

HY-132103

NHS ester-PEG3-S-methyl ethanethioate	PROTAC Linkers	Cancer
NHS ester-PEG3-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-141124

NHS-PEG4-(m-PEG4)3-ester	PROTAC Linkers	Cancer
NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-141125

NHS-PEG4-(m-PEG12)3-ester	PROTAC Linkers	Cancer
NHS-PEG4-(m-PEG12)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-130989

SuO-Glu-Val-Cit-PAB-MMAE NHS-Glutarate-Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W012166

N-Succinimidyl bromoacetate NHS-Bromoacetate	Biochemical Assay Reagents	Others
N-Succinimidyl bromoacetate is a heterobifunctional cross-linking reagent can be used to prepare peptide-protein immunogens .

HY-130112

N-Succinimidyloxycarbonylpropyl methanethiosulfonate NHS-C4-MTS	ADC Linker	Cancer
N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-126681

SC-VC-PAB-MMAE 2 Publications Verification NHS-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
SC-VC-PAB-MMAE is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB .

HY-D2291

*BODIPY TMR NHS* ester**	Fluorescent Dye	Others
BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .

HY-D1730

*AF488 NHS* ester**	Fluorescent Dye	Others
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .

HY-141166A

*(S,E)-TCO2-PEG3-NHS* ester**	Biochemical Assay Reagents	Cancer
(S,E)-TCO2-PEG3-NHS ester is NH₂ reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .

HY-160773

*DBCO-PEG6-NHS* ester**	Biochemical Assay Reagents	Others
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-D1568

*Sulfo-Cy7.5 NHS* ester**	Fluorescent Dye	Others
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .

HY-164165

*Paclitaxel-2′-succinate NHS* ester**	Microtubule/Tubulin Drug Derivative	Cancer
Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy .

HY-D2290

*Demethoxy-BODIPY TMR NHS* ester**	Fluorescent Dye	Others
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-160773A

*DBCO-C3-amide-PEG6-NHS* ester**	Biochemical Assay Reagents	Others
DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-C3-amide-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-D1567

*Cy7.5 NHS* ester**	Fluorescent Dye	Others
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study .

HY-D2178

*AF 568 NHS* ester**	Fluorescent Dye	Others
AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .

HY-164862

*N-(NHS* ester-PEG2)-N-bis(PEG3-azide)**	Biochemical Assay Reagents	Others
N-(NHS ester-PEG2)-N-bis(PEG3-azide) is a PEG linker with an NHS ester group and two terminal azide groups. N-(NHS ester-PEG2)-N-bis(PEG3-azide) can be utilized in Click Chemistry .

HY-W749072

*BP Fluor 568 NHS* ester**	Fluorescent Dye	Others
BP Fluor 568 NHS ester is an amine-reactive, orange fluorescent dye routinely used to label proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules (Ex/Em: 578 nm/602 nm) .

HY-135413

*MeCY5-NHS* ester** Sulfo-Cyanine5 NHS ester	DNA Stain	Inflammation/Immunology Cancer
MeCY5-NHS estera is a reactive dye. MeCY5-NHS estera can be used for the labeling of proteins and nucleic acids.

HY-150241

DOPE-NHS	Liposome	Others
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .

HY-W441011

DSPE-NHS	Biochemical Assay Reagents Liposome	Neurological Disease Inflammation/Immunology Cancer
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-D2105

TAMRA-PEG3-NHS	Fluorescent Dye	Others
TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2106

TAMRA-PEG4-NHS	Fluorescent Dye	Others
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2107

TAMRA-PEG8-NHS	Fluorescent Dye	Others
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-135413A

*Sulfo-CY5-NHS* ester potassium** Sulfo-Cyanine5 NHS ester potassium	DNA Stain	Inflammation/Immunology Cancer
MeCY5-NHS ester (potassium) is a reactive dye and can be used for labeling protein nucleic acid .

HY-140341A

*Sulfo-NHS-Acetate sodium*	PROTAC Linkers	Others
Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of PROTACs .

HY-150014

AMT-NHS	Others	Others
AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .

Cat. No.	Product Name	Type

HY-136304

**NHS-PEG1-SS-PEG1-NHS**	Drug Delivery
NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecule. NHS-PEG1-SS-PEG1-NHS can be used in proteins liposomes or nanoparticles .

HY-150241

DOPE-NHS	Drug Delivery
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .

HY-W441011

DSPE-NHS	Drug Delivery
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-W437745

*Desthiobiotin-NHS* ester**	Biochemical Assay Reagents
Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .

HY-W777012

*Acridinium C2 NHS* ester**	Cell Assay Reagents
Acridinium C2 NHS ester is a chemiluminescent label that is active for the development of protein and nucleic acid probes. Acridinium C2 NHS ester can be used in bioanalysis and diagnostics to provide highly sensitive detection solutions. Acridinium C2 NHS ester is widely used in medical research, especially in the monitoring and analysis of biomolecules.

HY-158072

*DOTAM-NHS-ester*	Chelators
DOTAM-NHS-esteris a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester can be used for conjugation of peptides and radionuclides.

HY-128890A

*DOTA-NHS-ester hexafluorophosphate TFA*	Chelators
DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.

HY-172355

*Azide-PEG-NHS* (MW 3500)**	3D Bioprinting
Azide-PEG-NHS (Mn 3500) is an azide PEG NHS ester that can be used for click chemistry reactions and can also be used to synthesize PEG hydrogels .

HY-172355A

*Azide-PEG-NHS* (MW 5000)**	3D Bioprinting
Azide-PEG-NHS (Mn 5000) is an azide PEG NHS ester that can be used for click chemistry reactions and can also be used to synthesize PEG hydrogels .

HY-W440697

*Cholesterol-PEG-NHS* (MW 1000)**	Drug Delivery
Cholesterol-PEG-NHS (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 1000) can be used in drug delivery research .

HY-W440702

*Cholesterol-PEG-NHS* (MW 2000)**	Drug Delivery
Cholesterol-PEG-NHS (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 2000) can be used in drug delivery research .

HY-W440704

*Cholesterol-PEG-NHS* (MW 5000)**	Carbohydrates
Cholesterol-PEG-NHS (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 5000) can be used in drug delivery research .

HY-W440703

*Cholesterol-PEG-NHS* (MW 3400)**	Drug Delivery
Cholesterol-PEG-NHS (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 3400) can be used in drug delivery research .

HY-W544595

*Methyltetrazine-PEG5-sulfo-NHS* ester sodium**	Biochemical Assay Reagents
Methyltetrazine-PEG5-sulfo-NHS ester (sodium) is a kind of biochemical reagent.

HY-W441013

*DSPE-PEG-NHS, MW 1000*	Drug Delivery
DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.

HY-W143136

6-(N-Trifluoroacetyl)caproic acid NHS TCFS	Biochemical Assay Reagents
6-(N-Trifluoroacetyl)caproic acid NHS (TCFS) is a biochemical reagent.

HY-W441014

*DSPE-PEG-NHS, MW 2000* DSPE-PEG2000-NHS	Drug Delivery
DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.

HY-172354B

*Acrylate-PEG-NHS* (MW 5000)**	3D Bioprinting
Acrylate-PEG-NHS (MW 5000) is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .

HY-172354A

*Acrylate-PEG-NHS* (MW 3500)**	3D Bioprinting
Acrylate-PEG-NHS (MW 3500) is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .

HY-172354

*Acrylate-PEG-NHS* (MW 2000)**	3D Bioprinting
Acrylate-PEG-NHS (MW 2000) is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .

HY-136158A

*6-Maleimidocaproic acid sulfo-NHS* sodium** Sulfo-EMCS	Drug Delivery
6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W441015A

*DSPE-m-PEG-NHS* (MW 3400)**	Drug Delivery
DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.

HY-W441012

*DSPE-PEG-NHS, MW 600*	Drug Delivery
DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.

HY-W123004

*PEG NHS* ester disulfide** N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid	Biochemical Assay Reagents
PEG NHS ester disulfide (N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid) is a biochemical reagent.

HY-155909

*m-PEG-NHS* ester (MW 3400)** mPEG-SC (MW 3400); mPEG-Succinimidyl ester (MW 3400)	Drug Delivery
m-PEG-NHS ester (MW 3400) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909A

*m-PEG-NHS* ester (MW 1000)** mPEG-SC (MW 1000); mPEG-Succinimidyl ester (MW 1000)	Drug Delivery
m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909C

*m-PEG-NHS* ester (MW 350)** mPEG-SC (MW 350); mPEG-Succinimidyl ester (MW 350)	Drug Delivery
m-PEG-NHS ester (MW 350) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909B

*m-PEG-NHS* ester (MW 550)** mPEG-SC (MW 550); mPEG-Succinimidyl ester (MW 550)	Drug Delivery
m-PEG-NHS ester (MW 550) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-W591424

*m-PEG-NHS* ester (MW 2000)** mPEG-SC (MW 2000); mPEG-Succinimidyl ester (MW 2000)	Drug Delivery
m-PEG-NHS ester (MW 2000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-140700

*m-PEG-NHS* ester (MW 20000)** mPEG-SC (MW 20000); mPEG-Succinimidyl ester (MW 20000)	Drug Delivery
m-PEG-NHS ester (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140699

*m-PEG-NHS* ester (MW 10000)** mPEG-SC (MW 10000); mPEG-Succinimidyl ester (MW 10000)	Drug Delivery
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140698

*m-PEG-NHS* ester (MW 5000)** mPEG-SC (MW 5000); mPEG-Succinimidyl ester (MW 5000)	Drug Delivery
m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W011412

TSTU	Biochemical Assay Reagents
TSTU is able to converse carboxylic acid to the corresponding N-hydroxysuccinimidyl (NHS) ester, and is utilized as coupling reagent in peptide chemistry .

HY-W440928

*Stearic acid-PEG-NHS* (MW 3400)**	Drug Delivery
DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.

HY-W440926

Stearic acid-PEG-NHS (MW 1000)

Drug Delivery

DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.

HY-D0975

Sulfo-SMCC sodium 4 Publications Verification	Biochemical Assay Reagents
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

HY-140677

mPEG-amine (MW 5000)

mPEG-NH2 (MW 5000)

Drug Delivery

mPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies .

HY-42972G

DBCO-acid (GMP)

Biochemical Assay Reagents

DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690) . DBCO-acid is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Product Name	Target	Research Area

HY-P99239

Rosopatamab HUJ-591	PSMA Radionuclide-Drug Conjugates (RDCs)	Cancer
Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 ( ¹⁷⁷Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency .

Cat. No.	Product Name		Classification

HY-150241

DOPE-NHS		Phospholipids
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .

HY-W441011

DSPE-NHS		Phospholipids
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-W440927

*Stearic acid-PEG-NHS, MW 2000*		Pegylated Lipids
Stearic acid-PEG-NHS, MW 2,000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.

HY-W441014

*DSPE-PEG-NHS, MW 2000* DSPE-PEG2000-NHS		Pegylated Lipids
DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.

HY-RS09290

NHS Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
NHS Human Pre-designed siRNA Set A contains three designed siRNAs for NHS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS22963

Nhs Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Nhs Rat Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS16532

Nhs Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Nhs Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-W441013

*DSPE-PEG-NHS, MW 1000*		Pegylated Lipids
DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.

HY-W441015A

*DSPE-m-PEG-NHS* (MW 3400)**		Pegylated Lipids
DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.

HY-W441012

*DSPE-PEG-NHS, MW 600*		Pegylated Lipids
DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.

HY-W441016

*DSPE-PEG-NHS, MW 5000*		Pegylated Lipids
DSPE-PEG-NHS, MW 5000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .

HY-155909

*m-PEG-NHS* ester (MW 3400)** mPEG-SC (MW 3400); mPEG-Succinimidyl ester (MW 3400)		Polymers
m-PEG-NHS ester (MW 3400) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909A

*m-PEG-NHS* ester (MW 1000)** mPEG-SC (MW 1000); mPEG-Succinimidyl ester (MW 1000)		Polymers
m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909C

*m-PEG-NHS* ester (MW 350)** mPEG-SC (MW 350); mPEG-Succinimidyl ester (MW 350)		Polymers
m-PEG-NHS ester (MW 350) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909B

*m-PEG-NHS* ester (MW 550)** mPEG-SC (MW 550); mPEG-Succinimidyl ester (MW 550)		Polymers
m-PEG-NHS ester (MW 550) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-W591424

*m-PEG-NHS* ester (MW 2000)** mPEG-SC (MW 2000); mPEG-Succinimidyl ester (MW 2000)		Polymers
m-PEG-NHS ester (MW 2000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-157745

*m-PEG-NHS* ester (MW 40000)** mPEG-SC (MW 40000); mPEG-Succinimidyl ester (MW 40000)		Polymers
m-PEG-NHS ester (MW 40000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects .

HY-W441005

Amino-Gly-Gly-DSPE hydrochloride		Phospholipids
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.

HY-W440706

Cholesterol-PEG-alcohol (MW 2000)		Pegylated Lipids
Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.

HY-W440945

Stearic acid-PEG-amine, MW 2000		Pegylated Lipids
Stearic acid-PEG-amine, MW 2000 is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.

HY-145547

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine 14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine		Phospholipids
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .

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