Search Result
Results for "
NHS
" in MedChemExpress (MCE) Product Catalog:
34
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-136304
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- HY-136133
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ADC Linker
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Cancer
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NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-D0802
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Biotin N-hydroxysuccinimide ester; NHS-Biotin
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Fluorescent Dye
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Others
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Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
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- HY-147117
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Others
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Others
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NHS-SS-Ac is an amine-reactive product synthesized from acetic acid .
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- HY-140129
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ADC Linker
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Cancer
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NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-147118
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ADC Linker
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Cancer
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NHS-SS-Ph is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-D0167
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Fluorescent Dye
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Others
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NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
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- HY-139326
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- HY-RS09290
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Small Interfering RNA (siRNA)
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Others
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NHS Human Pre-designed siRNA Set A contains three designed siRNAs for NHS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NHS Human Pre-designed siRNA Set A
NHS Human Pre-designed siRNA Set A
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- HY-145714
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Others
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Others
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NHS-NH-(diethylamino)ethyl benzoate is a compound that can be used for N-glycan labeling .
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- HY-139325
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Drug-Linker Conjugates for ADC
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Others
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NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) .
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- HY-W190737
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Others
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NHS-SS-dPEG4-biotin (cleavable) is a biodegradable crosslinker with efficient bioconjugation activity. NHS-SS-dPEG4-biotin (cleavable) can effectively connect biomolecules, optimize the efficiency of biolabeling, and be used in targeted compound delivery systems. NHS-SS-dPEG4-biotin (cleavable) can also play an important role in protein engineering and fluorescence imaging.
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- HY-138509
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PROTAC Linkers
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Cancer
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NHS ester-PEG13-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138511
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PROTAC Linkers
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Cancer
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NHS ester-PEG7-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138522
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PROTAC Linkers
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Cancer
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NHS-bis-PEG2-amide-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-148657
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NHS-Methotrexate
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Others
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Inflammation/Immunology
Cancer
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Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible
Methotrexate (HY-14519) influx carrier inhibitor. Aminopterin N-hydroxysuccinimide ester can be used for the research of rheumatoid arthritis and a number of cancers (such as acute lymphoblastic leukemia) .
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- HY-157338
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ADC Linker
Kinesin
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Cancer
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NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor .
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- HY-132103
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PROTAC Linkers
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Cancer
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NHS ester-PEG3-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141124
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PROTAC Linkers
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Cancer
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NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141125
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PROTAC Linkers
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Cancer
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NHS-PEG4-(m-PEG12)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130989
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NHS-Glutarate-Val-Cit-PAB-MMAE
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Drug-Linker Conjugates for ADC
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Cancer
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SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W012166
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NHS-Bromoacetate
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Biochemical Assay Reagents
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Others
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N-Succinimidyl bromoacetate is a heterobifunctional cross-linking reagent can be used to prepare peptide-protein immunogens .
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- HY-130112
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NHS-C4-MTS
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ADC Linker
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Cancer
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N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-D2291
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Fluorescent Dye
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Others
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BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
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- HY-D1730
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Fluorescent Dye
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Others
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AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .
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- HY-141166A
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Biochemical Assay Reagents
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Cancer
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(S,E)-TCO2-PEG3-NHS ester is NH2 reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .
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- HY-160773
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Biochemical Assay Reagents
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Others
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DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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- HY-D1568
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Fluorescent Dye
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Others
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Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
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- HY-164165
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Drug Derivative
Microtubule/Tubulin
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Cancer
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Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy .
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- HY-D2290
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Fluorescent Dye
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Others
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Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
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- HY-D1567
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Fluorescent Dye
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Others
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Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study .
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- HY-D2178
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Fluorescent Dye
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Others
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AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
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- HY-164862
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Biochemical Assay Reagents
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Others
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N-(NHS ester-PEG2)-N-bis(PEG3-azide) is a PEG linker with an NHS ester group and two terminal azide groups. N-(NHS ester-PEG2)-N-bis(PEG3-azide) can be utilized in Click Chemistry .
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- HY-150241
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Liposome
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Others
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DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
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- HY-D2105
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Fluorescent Dye
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Others
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TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-D2106
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Fluorescent Dye
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Others
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TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-D2107
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Fluorescent Dye
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Others
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TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-135413A
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- HY-140341A
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PROTAC Linkers
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Others
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Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of PROTACs .
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- HY-W441011
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Liposome
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Neurological Disease
Inflammation/Immunology
Cancer
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DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
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- HY-150014
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Others
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Others
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AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .
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- HY-129526
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ADC Linker
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Cancer
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Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate .
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- HY-118431
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Others
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Others
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DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products .
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- HY-151727
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ADC Linker
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Others
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Norbornene-NHS is a click chemistry reagent. Norbornene-NHS is a dienophile for conjugation via copper-free Click reaction with tetrazines .
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- HY-135413B
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Sulfo-Cyanine5 NHS ester triethylamine
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DNA Stain
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Others
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MeCY5-NHS ester (potassium) is a reactive dye and can be used for labeling protein nucleic acid .
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- HY-151758
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ADC Linker
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Others
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Methyltetrazine-PEG12-NHS ester is a click chemistry reagent containing an azide group. Methyltetrazine-PEG12-NHS ester reacts with compounds containing TCO to form stable covalent bonds .
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- HY-126504
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ADC Linker
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Cancer
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Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester.
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- HY-130085
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ADC Linker
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Cancer
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Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.
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- HY-156385
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PROTAC Linkers
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Cancer
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SCO-PEG8-NHS SCO is a PROTAC linker and belongs to the PEG class. SCO-PEG8-NHS SCO contains SCO and NHS esters that can be covalently bound to amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-D2477
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Fluorescent Dye
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Others
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Sulfo-QSY21-NHS is a fluorescent dye, which contains a NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. Sulfo-QSY21-NHS can be used in the synthesis of activity-based probes (ABPs) .
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- HY-126886
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ADC Linker
PROTAC Linkers
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Cancer
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Mal-PEG1-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-NHS ester is PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-156383
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PROTAC Linkers
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Cancer
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SCO-PEG3-NHS is a PEG linker with a terminal imine(NH) group. SCO-PEG3-NHS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-130410
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ADC Linker
PROTAC Linkers
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Cancer
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Bis-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-141170
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ADC Linker
PROTAC Linkers
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Cancer
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TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-148142
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- HY-148143
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- HY-117009
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ADC Linker
PROTAC Linkers
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Cancer
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Bis-PEG9-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-126889
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ADC Linker
PROTAC Linkers
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Cancer
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Bis-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-126890
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ADC Linker
PROTAC Linkers
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Cancer
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Bis-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130824
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PROTAC Linkers
ADC Linker
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Cancer
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Bis-PEG10-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130825
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PROTAC Linkers
ADC Linker
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Cancer
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Bis-PEG13-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG13-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130826
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ADC Linker
PROTAC Linkers
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Cancer
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Bis-PEG17-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG17-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130827
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PROTAC Linkers
ADC Linker
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Cancer
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Bis-PEG21-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG21-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130828
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PROTAC Linkers
ADC Linker
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Cancer
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Bis-PEG25-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG25-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-126885
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ADC Linker
PROTAC Linkers
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Cancer
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DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-126974
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130376
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130381
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130385
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130388
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-133066
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PROTAC Linkers
ADC Linker
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Inflammation/Immunology
Cancer
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m-PEG6-NHS ester is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-158072
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Biochemical Assay Reagents
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Others
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DOTAM-NHS-esteris a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester can be used for conjugation of peptides and radionuclides.
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- HY-156384
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- HY-126511
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ADC Linker
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Cancer
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Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-126512
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ADC Linker
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Cancer
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Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-150311
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PROTAC Linkers
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Others
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endo-BCN-PEG24-NHS ester is composed of a benzocyclonorbornene, a twenty-tetramer of polyethylene glycol (PEG) and an N-hydroxysuccinimide ester. endo-BCN-PEG24-NHS is utilized as linker for synthesis of PROTAC molecule .
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- HY-128890
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ADC Linker
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Cancer
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DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors .
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- HY-D1848
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Fluorescent Dye
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Others
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Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
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- HY-140273
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PROTAC Linkers
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Cancer
|
|
DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140271
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140272
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140274
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133439
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138744
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138734
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126513
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126516
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141167A
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-W437745
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .
|
-
- HY-W040289
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-130446
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG9-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-122413
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG7-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-124323
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-133064
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-133065
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130291
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-D2329
-
|
|
Fluorescent Dye
|
|
|
Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-D1309
-
|
|
Fluorescent Dye
|
|
|
Sulfo-cyanine3 NHS ester sodium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
-
- HY-111456
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-135819
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141166
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141168
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141169
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-122456
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-122459
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126882
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130829
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG15-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130830
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141387
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141357
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141356
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141083
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141082
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141100
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141104
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141105
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141107
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141108
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG17-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141109
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG25-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141110
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG37-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141106
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130195
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126717
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141096
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140614
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141272
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141171
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141271
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141269
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140892
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140890
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140891
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141270
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140615
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140963
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141102
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141101
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141098
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG25-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141097
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133389
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG36-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133482
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodo-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135941
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG9-NHS Ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W019794
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG16-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130903
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG49-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141085
-
|
|
PROTAC Linkers
|
Cancer
|
|
Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133378
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133493
-
|
|
PROTAC Linkers
|
Cancer
|
|
Folate-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132016
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132017
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132018
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134683
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138412
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetic-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138422
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138430
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141394
-
|
|
PROTAC Linkers
|
Cancer
|
|
Chloroacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130672
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG3-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138718
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG14-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138720
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138721
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138726
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143855
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-145090
-
|
|
PROTAC Linkers
ADC Linker
|
Others
|
|
DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130087
-
|
|
ADC Linker
|
Cancer
|
|
Bis-PEG3-NHS ester is a nonclaevable 3-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-130088
-
|
|
ADC Linker
|
Cancer
|
|
Bis-PEG2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-130089
-
|
|
ADC Linker
|
Cancer
|
|
Bis-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-126502
-
|
|
ADC Linker
|
Cancer
|
|
Mal-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126888
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-114512
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG1-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-124377
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140342
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135915
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-C5-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135920
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-C10-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W009037
-
|
|
PROTAC Linkers
|
Cancer
|
|
Maleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141167B
-
|
|
ADC Linker
|
Cancer
|
|
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-130184
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130474
-
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ADC Linker
PROTAC Linkers
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Cancer
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Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-D0893
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Fluorescent Dye
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Others
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NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed .
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- HY-155500
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Others
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Others
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Digoxigenin NHS ester is an activated ester which readily reacts with amino groups under mild conditions, attaching the digoxigenin (HY-B1025) moiety to proteins or amino-. Digoxigenin NHS ester can be used to label proteins and oligonucleotides .
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-
- HY-D1239
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Fluorescent Dye
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Others
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|
BODIPY R6G NHS ester is a borondipyrromethene dye. BODIPY R6G NHS ester can be conjugated with proteins. BODIPY R6G NHS ester can be used for intracellular traces .
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-
- HY-156313
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ADC Linker
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Cancer
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|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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-
- HY-156476
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ADC Linker
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Cancer
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|
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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-
- HY-156490
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ADC Linker
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Cancer
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|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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-
- HY-156491
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ADC Linker
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Cancer
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|
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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-
- HY-140888
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PROTAC Linkers
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Cancer
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|
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-140889
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PROTAC Linkers
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Cancer
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|
Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-156507
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ADC Linker
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Cancer
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|
DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-126505
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ADC Linker
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Cancer
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|
Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes .
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-
- HY-140068
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PROTAC Linkers
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Cancer
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|
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-140275
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PROTAC Linkers
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Cancer
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|
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-140070
-
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|
PROTAC Linkers
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Cancer
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|
endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-140069
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|
PROTAC Linkers
|
Cancer
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|
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-140276
-
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PROTAC Linkers
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Cancer
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|
DBCO-NHCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-133375
-
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|
PROTAC Linkers
|
Cancer
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|
DBCO-NHCO-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-138756
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PROTAC Linkers
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Cancer
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|
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-156991
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NODA-GA-NHS ester
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Radionuclide-Drug Conjugates (RDCs)
EGFR
|
Cancer
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|
NODAGA-NHS (NODA-GA-NHS ester) is a [64]Cu chelator and the dissociated form of DOTA-trastuzumab in vivo. NODAGA-NHS was added in 0.1 M borate buffer at a ratio of 5/20/100 and was able to effectively bind trastuzumab (10 mg/mL) (4°C, 20 h). The copper content of the [64]Cu-NODAGA-trastuzumab was up to 80%. After blood was drawn from the caudal vein of mice, [64]Cu-NODAGA-trastuzumab was injected and showed good tumor uptake in mice expressing HER2 tumors, showing good PET imaging tracking ability.
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-
- HY-160072
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Others
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Cancer
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|
Fmoc-NH-PEG2-NHS ester is an intermediate used in the synthesis of E-selectin antagonists [1] .
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-
- HY-W019793
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-
- HY-141358
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ADC Linker
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Cancer
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|
SPDP-PEG36-NHS ester is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-136048
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ADC Linker
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Cancer
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|
Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-130551
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PROTAC Linkers
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Cancer
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|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-133371
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PROTAC Linkers
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Cancer
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|
DBCO-NHCO-C4-NHS ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-C4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-W777012
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Fluorescent Dye
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|
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Acridinium C2 NHS ester is a chemiluminescent label that is active for the development of protein and nucleic acid probes. Acridinium C2 NHS ester can be used in bioanalysis and diagnostics to provide highly sensitive detection solutions. Acridinium C2 NHS ester is widely used in medical research, especially in the monitoring and analysis of biomolecules.
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-
- HY-157012
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-
- HY-42973
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ADC Linker
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Cancer
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|
DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-141165
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PROTAC Linkers
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Cancer
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|
TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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-
- HY-140139
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ADC Linker
|
Cancer
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|
PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-156323
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ADC Linker
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Cancer
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|
BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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-
- HY-156324
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ADC Linker
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Cancer
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|
BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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-
- HY-140759
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PROTAC Linkers
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Cancer
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|
Azido-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140758
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PROTAC Linkers
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Cancer
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|
Azido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG9-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140757
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|
PROTAC Linkers
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Cancer
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|
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140756
-
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PROTAC Linkers
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Cancer
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|
Azido-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140764
-
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|
PROTAC Linkers
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Cancer
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|
Azido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140761
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|
PROTAC Linkers
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Cancer
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|
Azido-PEG16-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG16-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140762
-
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|
PROTAC Linkers
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Cancer
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|
Azido-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG24-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140760
-
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|
PROTAC Linkers
|
Cancer
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|
Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-138463
-
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|
PROTAC Linkers
|
Cancer
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|
Azido-PEG36-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG36-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-138707
-
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|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG7-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-151835
-
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ADC Linker
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Others
|
|
DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
|
-
- HY-W776820
-
|
OXYL-1-NHS
|
Biochemical Assay Reagents
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Others
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|
1-Oxyl-2,2,5,5-tetramethylpyrroline-3-carboxylate NHS ester (OXYL-1-NHS) is an active acylating agent that can be used to spin label proteins and aminoacylated RNA species .
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-
- HY-141169B
-
|
|
ADC Linker
|
Cancer
|
|
(R)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-W008879
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040133
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040134
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141103
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141012
-
-
- HY-126880
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-140746
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|
|
PROTAC Linkers
|
Cancer
|
|
Benzyloxy carbonyl-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140977
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141118
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-140442
-
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|
PROTAC Linkers
|
Cancer
|
|
Fmoc-aminooxy-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-141120
-
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|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140623
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138441
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141119
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138730
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138729
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138731
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1615
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 530/550 NHS ester can be used for the stain of protein. BODIPY 530/550 NHS ester can be used for fluorescence OIM (oblique illumination microscopic) image .
|
-
- HY-153631
-
|
|
Others
|
Inflammation/Immunology
|
|
Sulfo-TAG NHS ester (disodium) is an N-hydroxysuccinimide ester that can be coupled to proteins via primary amine groups. Sulfo-TAG NHS ester (disodium) can be used for antibody labeling .
|
-
- HY-164724
-
|
|
ADC Linker
|
Cancer
|
|
Bis-PEG30-NHS ester is a non-claevable 30-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140755
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Aeide-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D1653
-
|
|
Reactive Oxygen Species
|
Others
|
|
BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules.
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-
- HY-133584
-
|
|
ADC Linker
|
Cancer
|
|
Bis-SS-C3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W096079
-
|
|
ADC Linker
|
Cancer
|
|
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-151827
-
|
|
ADC Linker
|
Others
|
|
DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
|
-
- HY-W156324
-
|
|
PROTAC Linkers
Liposome
|
Others
|
|
Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Biotin-PEGn-NHS ester can interact with free neutral avidin in solution and successfully target malignant glioma cells. Biotin-PEGn-NHS ester can also be grafted onto the amino group of GelMA to prepare biotin-modified functionalized hydrogel, gelatin methacryloyl (Bio-GelMA) .
|
-
- HY-141044
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cy5-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140341
-
|
|
PROTAC Linkers
|
Cancer
|
|
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151686
-
|
|
ADC Linker
|
Others
|
|
Bz-(Me)Tz-NHS is a click chemistry reagent containing an methyltetrazine group. Bz-(Me)Tz-NHS is 3rd generation Click-Linker for Cu-free click conjugation .
|
-
- HY-126509
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ADC Linker
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Cancer
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Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
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-
- HY-126507
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ADC Linker
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Cancer
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Mal-amido-PEG1-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
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-
- HY-126508
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ADC Linker
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Cancer
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|
Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
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-
- HY-D2166
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Fluorescent Dye
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Others
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AF 594 NHS ester is a derivative of the red fluorescent dye AF 594 with high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 NHS ester can form an ester bond by reacting the NHS group with ammonia, with maximum excitation wavelength of 594 nm .
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- HY-140141
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PROTAC Linkers
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Cancer
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PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-133479
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PROTAC Linkers
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Cancer
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Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-C3-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-111496
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Fluorescent Dye
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Others
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Sulfo-NHS-SS-biotin is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin can be used for the labeling and purifying of cell-surface protein .
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-
- HY-147287
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PSMA
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Cancer
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Glu-urea-Glu-NHS ester (compound 21) is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu which can be used as a pharmacophore for linking with prostate specific membrane antigen (PSMA) inhibitors .
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- HY-128890A
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Biochemical Assay Reagents
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Others
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DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.
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-
- HY-130107
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ADC Linker
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Cancer
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|
Ald-Ph-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC).
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-
- HY-154834
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-
- HY-140134
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ADC Linker
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Cancer
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PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-141169A
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ADC Linker
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Cancer
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|
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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-
- HY-151698
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ADC Linker
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Others
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|
TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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-
- HY-D2365
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Fluorescent Dye
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Others
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|
QSY 21 NHS, a dark quencher is an efficient energy transfer acceptor of the far red and NIR fluorescent probes. QSY 21 NHS works in
the wavelength range of 540-750 nm, and is frequently used in FRET applications. QSY 21 NHS does not emit fluorescence in normal conditions. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-D1310
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|
|
Fluorescent Dye
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|
|
Sulfo-cyanine3.5 NHS ester tripotassium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
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-
- HY-D1119C
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Fluorescent Dye
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Others
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|
AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection) .
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-
- HY-140418
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PROTAC Linkers
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Cancer
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|
t-Boc-Aminooxy-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140417
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|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140135
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PROTAC Linkers
|
Cancer
|
|
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2238
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-
- HY-D1315
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-
- HY-126517
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ADC Linker
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Cancer
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|
Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-123687
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ADC Linker
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Cancer
|
|
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-135973
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|
ADC Linker
|
Cancer
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|
BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D1119
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Fluorescent Dye
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Others
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|
AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light .
|
-
- HY-128890B
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ADC Linker
Biochemical Assay Reagents
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Cancer
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|
DOTA-NHS-ester (TFA) is used as a linker for affibody molecules, and it can be employed in small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. DOTA-NHS-ester can be used to label radiotracers or imaging probes for tumor detection .
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-
- HY-D1917
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Fluorescent Dye
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Others
|
|
ATTO 390 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 390 NHS ester is an NHS ester derivative of ATTO 390 that can be used to label proteins or antibodies.
|
-
- HY-D1929
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Fluorescent Dye
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Others
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|
ATTO 594 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 594 NHS ester is an NHS ester derivative of ATTO 594 that can be used to label proteins or antibodies.
|
-
- HY-D1932
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Fluorescent Dye
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Others
|
|
ATTO 590 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 NHS ester is an NHS ester derivative of ATTO 590 that can be used to label proteins or antibodies.
|
-
- HY-D1935
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Fluorescent Dye
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Others
|
|
ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
|
-
- HY-D1957
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Fluorescent Dye
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Others
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|
ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
|
-
- HY-D1959
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Fluorescent Dye
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Others
|
|
ATTO 565 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 NHS ester is an NHS ester derivative of ATTO 565 that can be used to label proteins or antibodies.
|
-
- HY-D1993
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Fluorescent Dye
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Others
|
|
ATTO 647 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 647 NHS ester is an NHS ester derivative of ATTO 647 that can be used to label proteins or antibodies.
|
-
- HY-D1999
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Fluorescent Dye
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Others
|
|
ATTO 665 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 665 NHS ester is an NHS ester derivative of ATTO 665 that can be used to label proteins or antibodies.
|
-
- HY-D2001
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|
|
Fluorescent Dye
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Others
|
|
ATTO 488 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 NHS ester is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
-
- HY-153524
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|
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Fluorescent Dye
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Others
|
|
ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.
|
-
- HY-D2019
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|
|
Fluorescent Dye
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Others
|
|
ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
|
-
- HY-D2026
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 514 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 NHS ester is an NHS ester derivative of ATTO 514 that can be used to label proteins or antibodies.
|
-
- HY-D2046
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|
|
Fluorescent Dye
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Others
|
|
ATTO 532 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 NHS ester is an NHS ester derivative of ATTO 532 that can be used to label proteins or antibodies.
|
-
- HY-D2058
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|
|
Fluorescent Dye
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Others
|
|
ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
|
-
- HY-D2062
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|
|
Fluorescent Dye
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Others
|
|
ATTO 740 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 NHS ester is an NHS ester derivative of ATTO 740 that can be used to label proteins or antibodies.
|
-
- HY-D2073
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.
|
-
- HY-133405
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126908
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130283
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136032
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136033
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-126520
-
|
|
ADC Linker
|
Cancer
|
|
N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126521
-
|
|
ADC Linker
|
Cancer
|
|
N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126522
-
|
|
ADC Linker
|
Cancer
|
|
N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126523
-
|
|
ADC Linker
|
Cancer
|
|
N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-135414A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
|
-
- HY-D1691
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY-581/591 NHS ester is a bright, red fluorescent dye (excitation: 581 nm; emission: 591 nm). BODIPY-581/591 NHS ester shows unique hydrophobic properties for staining lipids, membranes, and other lipophilic compounds .
|
-
- HY-D1662
-
|
BODIPY 558/568SE
|
Fluorescent Dye
|
Others
|
|
BDP 558/568 NHS ester is a borondipyrromethene fluorophore with emission in the yellow part of the spectrum. BDP 558/568 NHS ester is an amine reactive NHS ester, and the absorption and emission spectra of BDP 558/568 NHS ester are similar with TAMRA, BDP TMR, Cyanine3, and sulfo-Cyanine3 .
|
-
- HY-141386
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG2-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140011
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-C2-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141122
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135931
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG11-C2-NHS Ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138414
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetic-PEG1-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1568A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications .
|
-
- HY-145368
-
|
|
LYTACs
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Others
|
|
Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC .
|
-
- HY-W019795
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-163792
-
-
- HY-115524
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry . DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151698B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(R,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-151698A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-W087028
-
-
- HY-140025
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-PEG4-CH2CO2-NHS (compound P-7) is a PEG derivative containing a propargyl group and an NHS group. Propargyl-PEG4-CH2CO2-NHS is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG4-CH2CO2-NHS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
|
-
- HY-130091
-
|
|
ADC Linker
|
Cancer
|
|
NHPI-PEG4-C2-NHS ester is an ADC Linker, which can be used to synthesize antibody-drug conjugates (ADCs) .
|
-
- HY-136134
-
|
|
ADC Linker
|
Cancer
|
|
SS-bis-amino-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-149117
-
|
|
Fluorescent Dye
|
Others
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-140142
-
|
|
PROTAC Linkers
|
Cancer
|
|
PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Azido-PEG11-NHS carbonate ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141268
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135959
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NH-PEG7-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NH-PEG7-C2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W414380
-
|
|
Fluorescent Dye
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Others
|
|
Bdp tr nhs ester is a chemiluminescent coupling compound with a long excited state lifetime for immunoassays and is suitable for microscopy and fluorescence polarization analysis applications. NHS ester can react specifically and efficiently with the side chains of primary amines such as lysine residues or amino silane coated surfaces under neutral or weakly basic conditions to form covalent bonds .
|
-
- HY-130093
-
|
|
ADC Linker
|
Cancer
|
|
NHPI-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-130095
-
|
|
ADC Linker
|
Cancer
|
|
NHPI-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-133579
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-134620
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine 5 NHS ester tetrafluoroborate (Compound Cy5) is a cyanine dye that is used to in fluorescence detection of macromolecules. Cyanine 5 NHS ester tetrafluoroborate exhibits an excitation wavelength of 638 nm .
|
-
- HY-131326
-
-
- HY-130390
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-135414
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
-
- HY-120773
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126881
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG2-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140067
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG2-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140767
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG8-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133581
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-148840
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo DBCO-PEG3-NHS ester is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .
|
-
- HY-126381
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-135029
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-N-PEG3-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141115
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-NO2-Ph-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141116
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136964
-
|
|
Others
|
Others
|
|
Sulfo-NHS-Biotin (sodium) stongly label single SDS-2ME soluble cuticular protein .
|
-
- HY-D1389
-
|
Sulfo-Cyanine5.5 NHS ester tripotassium
|
Fluorescent Dye
|
Others
|
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
|
-
- HY-130931
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-NH-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133539
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-C8-amido-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-115545
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC) . DBCO-NHS ester 3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141336
-
|
DL-α-Lipoic acid-NHS
|
PROTAC Linkers
|
Cancer
|
|
α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141117
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1352
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
-
- HY-133535
-
|
PA-JF646-NHS
|
Fluorescent Dye
|
Others
|
|
PA Janelia Fluor® 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag ® and SNAP-tag ®. PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λExcitation/emission~650/664 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-W440704
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-NHS (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 5000) can be used in drug delivery research .
|
-
- HY-W440697
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-NHS (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 1000) can be used in drug delivery research .
|
-
- HY-W440702
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-NHS (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 2000) can be used in drug delivery research .
|
-
- HY-W440703
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-NHS (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 3400) can be used in drug delivery research .
|
-
- HY-110210
-
|
BODIPY FL,SE
|
Fluorescent Dye
|
Others
|
|
BODIPY-FL NHS ester (BODIPY FL, SE) is an amine-reactive fluorescent probe. The maximum excitation/emission values are 502/511 nm. BODIPY-FL NHS ester can be used to synthesize protease substrates .
|
-
- HY-D1872
-
|
|
Fluorescent Dye
|
Others
|
|
800CW NHS ester is a near infrared probe that can be used for labeling lysine residues (λmax=776 nm) .
|
-
- HY-154802
-
|
|
ADC Linker
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-140558
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140571
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140572
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140557
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG3-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140583
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136157
-
|
|
ADC Linker
|
Cancer
|
|
Py-ds-dmBut-amido-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-133536
-
|
PA-JF549-NHS
|
Fluorescent Dye
|
Others
|
|
PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D0799
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-NHS-LC-Biotin sodium is an amine-reactive biotinylation reagent that can be used for antibody labeling .
|
-
- HY-160408
-
|
|
ADC Linker
|
Cancer
|
|
Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W040113
-
-
- HY-W544595
-
-
- HY-D1119A
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester (tripotassium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
-
- HY-D1119B
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
-
- HY-130086
-
|
|
ADC Linker
|
Cancer
|
|
Bis- PEG4- NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-140140
-
|
|
ADC Linker
|
Cancer
|
|
PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140138
-
|
|
ADC Linker
|
Cancer
|
|
PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-135415
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 NHS ester chloride is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
-
- HY-D0923
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3.5 NHS ester is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .
|
-
- HY-D1730A
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 NHS ester TEA is an amine specific fluorescence probe (λem=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-164085
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azide-C3-NHCO-C3-NHS ester is utilized as a linker in chemical synthesis, especially when rapid and specific ligation via click chemistry is required .
|
-
- HY-W441013
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.
|
-
- HY-135414B
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
-
- HY-130106
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG1-C2-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-130101
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-130104
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-W143136
-
-
- HY-130312
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140582
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130077
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130436
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133412
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133413
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-150015
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent .
|
-
- HY-D1352A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
-
- HY-D2157
-
|
Coumarin 343-aminohexanoic acid-NHS ester
|
Fluorescent Dye
|
Others
|
|
Coumarin 343 X NHS ester is a homologue of Coumarin 343 (HY-W267364). Coumarin 343 is a hydrophilic fluorescent probe for use in microfluids.
|
-
- HY-126526
-
|
|
ADC Linker
|
Cancer
|
|
N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126528
-
|
|
ADC Linker
|
Cancer
|
|
N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130109
-
|
|
ADC Linker
|
Cancer
|
|
N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130490
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-bis-amido-SS-NHS is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-141047
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-(N,N'-PEG4-NHS ester)-Cy5 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040254
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-LC-LC-NHS is a SMCC cross-linking reagent that can be used to mark antibody and other small molecules, such as Paclitaxel .
|
-
- HY-D1661
-
|
|
Fluorescent Dye
|
Others
|
|
BDP 564/570 NHS ester is a lypophilic orange fluorescein dye, can be used for the labeling of amine containing biomolecules, including amine-modified oligonucleotides.
|
-
- HY-140585
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-DBCO-N-bis(PEG2-C2-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151742
-
|
|
ADC Linker
|
Others
|
|
Norbornene-methyl-NHS is a click chemistry reagent containing a TCO group. Dienophile for conjugation via Diels-Alder-reaction, i.e. copper-free click reaction with tetrazines .
|
-
- HY-140766
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138350
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG10-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D0923A
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3.5 NHS ester TEA is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .
|
-
- HY-135415A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 NHS ester chloride TEA is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
-
- HY-133431
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-SS-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D2175
-
|
|
Fluorescent Dye
|
Others
|
|
AF 555 NHS ester is a bright, orange-red fluorescence probe. AF 555 NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. AF 555 exhibits average excitation wavelengths under green laser and red laser of 510 nm and 610 nm, respectively .
|
-
- HY-140102
-
|
|
ADC Linker
|
Cancer
|
|
Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141113
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141084
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-PEG6-bis-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141172
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG2-Sulfo-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141111
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG8-ethoxycarbonyl--NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141172A
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG2-Sulfo-NHS ester sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W440927
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-NHS, MW 2,000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.
|
-
- HY-140763
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D0892
-
|
|
Biochemical Assay Reagents
|
Others
|
|
NSP-DMAE-NHS is an acridinium ester chemiluminescence reagent containing N-sulfopropyl group. It is useful in the clinical diagnostics industry, especially in automated immunochemistry analyzers such as the ADVIA Centaur system from Siemens Healthcare Diagnostics.
|
-
- HY-136040
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133466
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-126524
-
|
|
ADC Linker
|
Cancer
|
|
N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-Ph-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140765
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W441014
-
|
DSPE-PEG2000-NHS
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-44149
-
|
|
ADC Linker
|
Cancer
|
|
m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W035129
-
|
|
Biochemical Assay Reagents
|
Others
|
|
endo-BCN-NHS carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-126514
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-O-C1-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126515
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140561
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140560
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140559
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W096149
-
|
|
Biochemical Assay Reagents
|
Others
|
|
exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D0799A
-
|
|
Fluorescent Dye
|
|
|
Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
|
-
- HY-133583
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-O-C1-amido-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D1041
-
|
ICG NHS ester
|
Fluorescent Dye
|
Cancer
|
|
ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
|
-
- HY-133544
-
|
|
ADC Linker
|
Cancer
|
|
Mal-CO-PEG5- NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-D1611
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .
|
-
- HY-D1974
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 610 NHS-Ester is an activated ester derivative of ATTO 610, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 616/633 nm.
|
-
- HY-D1979
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 NHS-Ester is an activated ester derivative of ATTO 725, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
-
- HY-D1983
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 NHS-Ester is an activated ester derivative of ATTO 620, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 620/642 nm.
|
-
- HY-140119
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140680
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG-Lys-NHS ester (MW 20000) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140681
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG-Lys-NHS ester (MW 40000) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151769
-
|
|
ADC Linker
|
Others
|
|
TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-140866
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D1849
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.
|
-
- HY-136158A
-
|
Sulfo-EMCS
|
PROTAC Linkers
|
Cancer
|
|
6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1496
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescent Red Mega 485 NHS-ester is an amine conjugating fluorescent biolabel that can be used to label proteins .
|
-
- HY-141046
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141045
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140768
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-O-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141123
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-C6-Gly-Leu-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-133585
-
|
|
ADC Linker
|
Cancer
|
|
Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-147172
-
|
|
Fluorescent Dye
|
Others
|
|
Ru(bpy)2(dcbpy)NHS (dihexafluorophosphate) combines with gold nanoparticle amplification can be used for the determination of lysozyme with electrochemiluminescence .
|
-
- HY-136158
-
|
Sulfo-EMCS free acid
|
PROTAC Linkers
|
Cancer
|
|
6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126525
-
|
|
ADC Linker
|
Cancer
|
|
4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-135966
-
|
|
ADC Linker
|
Cancer
|
|
Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG3-SS-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133545
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Ph-CONH-PEG4- NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-D2189
-
|
IRDye 700DX NHS ester
|
Fluorescent Dye
|
Others
|
|
IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
|
-
- HY-141048
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126510
-
|
|
ADC Linker
|
Cancer
|
|
MC-PEG2-C2- NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-140770
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-aminoacetic acid-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D1692
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 650/665 NHS ester is bright, far-red fluorescent dye that can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules . Ex / Em = 646 / 660 nm
|
-
- HY-W441015A
-
|
|
Liposome
|
Others
|
|
DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-D2096
-
|
|
Fluorescent Dye
|
Others
|
|
Alexa fluor 647 NHS ester can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-W441012
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-133582
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG3-C1- NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W441016
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 5000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
|
-
- HY-140340
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-pentanoic acid-NHS-SO3Na is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1322
-
|
|
Fluorescent Dye
|
|
|
Cyanine5.5 NHS ester tetrafluoroborate belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
-
- HY-W123004
-
|
N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid
|
Biochemical Assay Reagents
|
Others
|
|
PEG NHS ester disulfide (N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid) is a biochemical reagent.
|
-
- HY-112498
-
|
Cyanine3 NHS ester
|
Fluorescent Dye
|
Others
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-W071006
-
|
2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate
|
ADC Linker
|
Cancer
|
|
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D2096A
-
|
|
Fluorescent Dye
|
Others
|
|
Alexa fluor 647 NHS ester TEA can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-155909
-
|
mPEG-SC (MW 3400); mPEG-Succinimidyl ester (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-NHS ester (MW 3400) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909A
-
|
mPEG-SC (MW 1000); mPEG-Succinimidyl ester (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909B
-
|
mPEG-SC (MW 550); mPEG-Succinimidyl ester (MW 550)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-NHS ester (MW 550) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909C
-
|
mPEG-SC (MW 350); mPEG-Succinimidyl ester (MW 350)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-NHS ester (MW 350) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-W591424
-
|
mPEG-SC (MW 2000); mPEG-Succinimidyl ester (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-NHS ester (MW 2000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-D1756
-
|
|
Fluorescent Dye
|
Others
|
|
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.
|
-
- HY-157745
-
|
mPEG-SC (MW 40000); mPEG-Succinimidyl ester (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-NHS ester (MW 40000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects .
|
-
- HY-140698
-
|
mPEG-SC (MW 5000); mPEG-Succinimidyl ester (MW 5000)
|
PROTAC Linkers
|
Cancer
|
|
m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140699
-
|
mPEG-SC (MW 10000); mPEG-Succinimidyl ester (MW 10000)
|
PROTAC Linkers
|
Cancer
|
|
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140700
-
|
mPEG-SC (MW 20000); mPEG-Succinimidyl ester (MW 20000)
|
PROTAC Linkers
|
Cancer
|
|
m-PEG-NHS ester (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190766
-
|
S-Acetyl-dPEG(R)8-NHS ester; Polyethylene glycol
|
Others
|
|
|
dPEG(R)8-SATA (S-Acetyl-dPEG(R)8-NHS ester) is a bioconjugation reagent with excellent biocompatibility and high selectivity. dPEG(R)8-SATA can be used to label and cross-link biomolecules and promote the interaction between biomolecules. dPEG(R)8-SATA plays an important role in bioimaging and compound delivery systems.
|
-
- HY-D1232
-
|
|
Fluorescent Dye
|
Others
|
|
BDP TMR NHS ester is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-112498A
-
|
Cyanine3 NHS ester bromide
|
Fluorescent Dye
|
Others
|
|
Cy3 NHS ester bromide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D2328
-
|
Alexa Fluor 680 succinimidyl ester
|
Fluorescent Dye
|
Others
|
|
Alexa Fluor 680 NHS ester is a near-infrared (NIR) fluorescent dye. The Alexa Fluor 680 group has an absorption maximum at 679 nm and an emission maximum at 720 nm .
|
-
- HY-140865
-
|
|
PROTAC Linkers
|
Cancer
|
|
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D1800
-
|
VF 680 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1801
-
|
VF 488 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1790
-
|
VF 640 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1802
-
|
VF 425 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1803
-
|
VF 565 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 565 SE (VF 565 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=563 nm/594 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1797
-
|
VF 660 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1798
-
|
VF 350 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1799
-
|
VF 568 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 568 SE (VF 568 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=573 nm/595 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1791
-
|
VF 750 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1792
-
|
VF 555 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 555 SE (VF 555 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=550 nm/561 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1794
-
|
VF 405 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1795
-
|
VF 532 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1796
-
|
VF 594 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D0049
-
|
6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester
|
DNA Stain
|
Others
|
|
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .
|
-
- HY-D1388
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D1635
-
|
Biotin-XX-SSE
|
Fluorescent Dye
|
Infection
|
|
Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .
|
-
- HY-D1223
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 NHS ester diTEA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-110212
-
|
BODIPY TR-X NHS Ester
|
Fluorescent Dye
|
Others
|
|
BODIPY TR-X (BODIPY TR-X NHS Ester) is a potent fluorescent dye. BODIPY TR-X can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, red fluorescent light. (λex=545 nm, λem=560 nm) .
|
-
- HY-D1596
-
|
Cy3.5 NHS ester chloride; Cy 3.5 chloride
|
Fluorescent Dye
|
Others
|
|
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-131026
-
|
JF635, SE; JF635, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-P6021A
-
|
|
|
Others
|
|
HBpep-SP TFA is the TFA salt form of HBpep-SP (HY-P6021). HBpep-SP TFA is utilized for delivery and release of proteins, peptides and mRNA .
|
-
- HY-D0819A
-
|
Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt
|
Fluorescent Dye
|
Others
|
|
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
|
-
- HY-D1596A
-
|
Cy3.5 NHS ester bromide; Cy 3.5 bromide
|
Fluorescent Dye
|
Others
|
|
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-D0819
-
CY5-SE
Maximum Cited Publications
15 Publications Verification
Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
|
Fluorescent Dye
|
Others
|
|
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm):649, Emission (nm): 670.
|
-
- HY-138658
-
|
JF526, SE; JF526, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D0925
-
|
Cyanine5.5 NHS ester
|
Biochemical Assay Reagents
|
Others
|
|
Cy5.5-SE (Cyanine5.5 NHS ester) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
-
- HY-131025
-
|
JF585, SE; JF585, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-138660
-
|
HM-JF526 NHS
|
Fluorescent Dye
|
Others
|
|
HM Janelia Fluor® 526, SE (HM-JF526 NHS) is a derivative of hydroxymethyl JF526 (HM-JF526). SMLM (single-molecule localization microscopy) imaging in standard phosphate-buffered saline (pH 7.4) revealed that the HM-JF526 label showed spontaneous blinking behavior throughout the imaging session and did not require short-wavelength activation light . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D0925A
-
|
Cyanine5.5 NHS ester (DIPEA)
|
DNA Stain
Fluorescent Dye
|
Others
|
|
Cy5.5-SE (Cyanine5.5 NHS ester) DIPEA is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
-
- HY-D0925B
-
|
Cyanine5.5 NHS ester TEA
|
Fluorescent Dye
|
Others
|
|
Cy5.5-SE TEA (Cyanine5.5 NHS ester TEA) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
-
- HY-47373
-
|
|
PROTAC Linkers
|
Cancer
|
|
Folate-PEG3-C2-acid is the acid fragment of Folate-PEG3-NHS ester (HY-133493), which belongs to the PEG-type PROTAC linker and is used to synthesize PROTAC molecules.
|
-
- HY-D1106
-
|
|
Fluorescent Dye
|
Cancer
|
|
BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
|
-
- HY-136159
-
|
|
PROTAC Linkers
|
Cancer
|
|
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W422359A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Aminopurine-O-Ph-NHCO-C3-COOH hydrochloride is the acid form in the previous step of the final product 2-Aminopurine-O-Ph-NHCO-C3-NHS ester (HY-143336) .
|
-
- HY-D0823
-
-
- HY-126887
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-128925
-
AMAS
1 Publications Verification
|
ADC Linker
|
Cancer
|
|
AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
|
-
- HY-W011412
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TSTU is able to converse carboxylic acid to the corresponding N-hydroxysuccinimidyl (NHS) ester, and is utilized as coupling reagent in peptide chemistry .
|
-
- HY-D1906
-
|
|
Fluorescent Dye
|
Others
|
|
CellTracker Green BODIPY (compound 31) is a green fluorescent dye that acts as an intracellular environmental tracer .
|
-
- HY-D2309
-
|
|
Fluorescent Dye
|
Others
|
|
IRDye700Dx (IRDye 700DX NHS ester) Maleimide is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
|
-
- HY-W440926
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-W440928
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.
|
-
- HY-103688
-
|
|
ADC Cytotoxin
|
Cancer
|
|
AcBut-N-Ac-γ-Calicheamicin is an ADC cytotoxic payload that induces cell cycle arrest and apoptosis by causing DNA double-strand breaks. AcBut-N-Ac-γ-Calicheamicin is primarily used in the synthesis of antibody-drug conjugates (ADC) and holds promise for research in the field of cancer, including acute lymphoblastic leukemia (ALL) and other hematological malignancies .
|
-
- HY-D0975
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
|
-
- HY-129655
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules .
|
-
- HY-W441005
-
|
|
Liposome
|
Cancer
|
|
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.
|
-
- HY-137251
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo-MBS sodium is a heterobifunctional crosslinker with a maleimide group and an N-hydroxysuccinimide (NHS) ester group, which can react with cysteine residues and lysine residues on proteins. Sulfo-MBS sodium be used for protein cross-linking studies .
|
-
- HY-D1111
-
|
AFDye 568 NHS Ester
|
Fluorescent Dye
|
Others
|
|
TFAX 568, SE is an orange fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 568, SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
|
-
- HY-D1658
-
|
|
Fluorescent Dye
|
Others
|
|
BDP 581/591 amine hydrochloride is a BODIPY dye linker. BDP 581/591 is a universal, photostable fluorophore. The addition of the amine group allows for the compound to react with carboxylic acids, activated NHS esters and other carbonyl groups .
|
-
- HY-157262
-
|
|
Others
|
Infection
|
Methyl isonicotinate-(CH2)2-COOH (hapten 2b) is a hapten that can be activated with NHS and DCC. Methyl isonicotinate-(CH2)2-COOH has more immunogenicity and hydrophobicity .
|
-
- HY-D0048
-
|
5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester
|
Fluorescent Dye
|
Others
|
|
5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability.
|
-
- HY-160885
-
|
|
ADC Cytotoxin
|
Others
|
|
NH2-Gly-PAB-Exatecan-D-glucuronic acid (Compound 8) is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
|
-
- HY-100216
-
SPDP
5 Publications Verification
SPDP Crosslinker; Py-ds-Prp-OSu
|
ADC Linker
|
Cancer
|
|
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
- HY-141385
-
|
3-(2-Bromoacetamido)propanoic acid NHS ester
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131030
-
|
JF669, SE; JF669, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-130735
-
|
JF646, SE; JF646, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-130736
-
|
JF549, SE; JF549, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-131020
-
|
JF525, SE; JF525, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 525, SE (JF525, SE) is a yellow fluorescent dye (Ex = 525 nm; Em = 549 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D1085
-
|
|
Fluorescent Dye
|
Others
|
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
-
- HY-D1372
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
-
- HY-W440706
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
|
-
- HY-D1372A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
-
- HY-126493
-
|
|
Drug-Linker Conjugates for ADC
Microtubule/Tubulin
|
Cancer
|
|
DM4-SPDP is a agent-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody agent conjugate . SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls .
|
-
- HY-P99239
-
|
HUJ-591
|
PSMA
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 ( 177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency .
|
-
- HY-W440945
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-amine, MW 2000 is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.
|
-
- HY-42972
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690) . DBCO-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-141147
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-D1363
-
|
|
Fluorescent Dye
|
Others
|
|
BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .
|
-
- HY-W712314
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG-amine (MW 5000) is a PEG Linker. The reactive primary amine or NH2 rapidly react with aldehyde, ketone to form imine. Imine upon further reduction forms secondary amine via reductive amination. Amine reacts with activated carboxyl acid, NHS ester to form stable amide bonds. 4-Arm PEG reagents are useful crosslinking reagent and used for drug delivery .
|
-
- HY-141148
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Cbz-N-amido-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-160885A
-
|
|
ADC Cytotoxin
|
Cancer
|
|
NH2-Gly-PAB-Exatecan-D-glucuronic acid formic (Compound 8) is the formic salt form of H2N-Gly-PAB-Exatecan-D-glucuronic acid. H2N-Gly-PAB-Exatecan-D-glucuronic acid formic is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
|
-
- HY-140677
-
|
mPEG-NH2 (MW 5000)
|
PROTAC Linkers
|
Cancer
|
|
mPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies .
|
-
- HY-42972G
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690) . DBCO-acid is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-145547
-
|
14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine
|
Liposome
|
Metabolic Disease
|
|
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0802
-
|
Biotin N-hydroxysuccinimide ester; NHS-Biotin
|
Fluorescent Dyes/Probes
|
|
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
|
-
- HY-D1567
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study .
|
-
- HY-D2178
-
|
|
Fluorescent Dyes/Probes
|
|
AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
|
-
- HY-D0167
-
|
|
Fluorescent Dyes/Probes
|
|
NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
|
-
- HY-D2291
-
|
|
Fluorescent Dyes/Probes
|
|
BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-D1568
-
|
|
Dyes
|
|
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
|
-
- HY-D2290
-
|
|
Fluorescent Dyes/Probes
|
|
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
|
-
- HY-D2105
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.
|
-
- HY-D2106
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.
|
-
- HY-D2107
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.
|
-
- HY-D2477
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-QSY21-NHS is a fluorescent dye, which contains a NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. Sulfo-QSY21-NHS can be used in the synthesis of activity-based probes (ABPs) .
|
-
- HY-D1848
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-D2329
-
|
|
Fluorescent Dyes/Probes
|
|
Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-D1309
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-cyanine3 NHS ester sodium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
-
- HY-141085
-
|
|
Fluorescent Dyes/Probes
|
|
Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D0893
-
|
|
Fluorescent Dyes/Probes
|
|
NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed .
|
-
- HY-D1239
-
|
|
Dyes
|
|
BODIPY R6G NHS ester is a borondipyrromethene dye. BODIPY R6G NHS ester can be conjugated with proteins. BODIPY R6G NHS ester can be used for intracellular traces .
|
-
- HY-D1615
-
|
|
Dyes
|
|
BODIPY 530/550 NHS ester can be used for the stain of protein. BODIPY 530/550 NHS ester can be used for fluorescence OIM (oblique illumination microscopic) image .
|
-
- HY-D1653
-
|
|
Fluorescent Dyes/Probes
|
|
BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules.
|
-
- HY-D2166
-
|
|
Fluorescent Dyes/Probes
|
|
AF 594 NHS ester is a derivative of the red fluorescent dye AF 594 with high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 NHS ester can form an ester bond by reacting the NHS group with ammonia, with maximum excitation wavelength of 594 nm .
|
-
- HY-111496
-
|
|
Dyes
|
|
Sulfo-NHS-SS-biotin is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin can be used for the labeling and purifying of cell-surface protein .
|
-
- HY-D2365
-
|
|
Dyes
|
|
QSY 21 NHS, a dark quencher is an efficient energy transfer acceptor of the far red and NIR fluorescent probes. QSY 21 NHS works in
the wavelength range of 540-750 nm, and is frequently used in FRET applications. QSY 21 NHS does not emit fluorescence in normal conditions. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-D1310
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-cyanine3.5 NHS ester tripotassium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
-
- HY-D1119C
-
|
|
Fluorescent Dyes/Probes
|
|
AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection) .
|
-
- HY-D2238
-
-
- HY-D1315
-
|
|
Dyes
|
|
Cyanine7 NHS ester tetrafluoroborate is a Cyanine7 dye.
|
-
- HY-123687
-
|
|
Dyes
|
|
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D1119
-
|
|
Fluorescent Dyes/Probes
|
|
AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light .
|
-
- HY-D1917
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 390 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 390 NHS ester is an NHS ester derivative of ATTO 390 that can be used to label proteins or antibodies.
|
-
- HY-D1929
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 594 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 594 NHS ester is an NHS ester derivative of ATTO 594 that can be used to label proteins or antibodies.
|
-
- HY-D1932
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 590 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 NHS ester is an NHS ester derivative of ATTO 590 that can be used to label proteins or antibodies.
|
-
- HY-D1935
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
|
-
- HY-D1957
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
|
-
- HY-D1959
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 565 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 NHS ester is an NHS ester derivative of ATTO 565 that can be used to label proteins or antibodies.
|
-
- HY-D1993
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 647 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 647 NHS ester is an NHS ester derivative of ATTO 647 that can be used to label proteins or antibodies.
|
-
- HY-D1999
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 665 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 665 NHS ester is an NHS ester derivative of ATTO 665 that can be used to label proteins or antibodies.
|
-
- HY-D2001
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 488 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 NHS ester is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
-
- HY-153524
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.
|
-
- HY-D2019
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
|
-
- HY-D2026
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 514 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 NHS ester is an NHS ester derivative of ATTO 514 that can be used to label proteins or antibodies.
|
-
- HY-D2046
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 532 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 NHS ester is an NHS ester derivative of ATTO 532 that can be used to label proteins or antibodies.
|
-
- HY-D2058
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
|
-
- HY-D2062
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 740 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 NHS ester is an NHS ester derivative of ATTO 740 that can be used to label proteins or antibodies.
|
-
- HY-D2073
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.
|
-
- HY-135414A
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
|
-
- HY-D1691
-
|
|
Fluorescent Dyes/Probes
|
|
BODIPY-581/591 NHS ester is a bright, red fluorescent dye (excitation: 581 nm; emission: 591 nm). BODIPY-581/591 NHS ester shows unique hydrophobic properties for staining lipids, membranes, and other lipophilic compounds .
|
-
- HY-D1662
-
|
BODIPY 558/568SE
|
Fluorescent Dyes/Probes
|
|
BDP 558/568 NHS ester is a borondipyrromethene fluorophore with emission in the yellow part of the spectrum. BDP 558/568 NHS ester is an amine reactive NHS ester, and the absorption and emission spectra of BDP 558/568 NHS ester are similar with TAMRA, BDP TMR, Cyanine3, and sulfo-Cyanine3 .
|
-
- HY-D1568A
-
|
|
Dyes
|
|
Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications .
|
-
- HY-149117
-
|
|
Fluorescent Dyes/Probes
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-W414380
-
|
|
Fluorescent Dyes/Probes
|
|
Bdp tr nhs ester is a chemiluminescent coupling compound with a long excited state lifetime for immunoassays and is suitable for microscopy and fluorescence polarization analysis applications. NHS ester can react specifically and efficiently with the side chains of primary amines such as lysine residues or amino silane coated surfaces under neutral or weakly basic conditions to form covalent bonds .
|
- HY-134620
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine 5 NHS ester tetrafluoroborate (Compound Cy5) is a cyanine dye that is used to in fluorescence detection of macromolecules. Cyanine 5 NHS ester tetrafluoroborate exhibits an excitation wavelength of 638 nm .
|
- HY-135414
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
- HY-D1389
-
|
Sulfo-Cyanine5.5 NHS ester tripotassium
|
Fluorescent Dyes/Probes
|
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
|
- HY-D1352
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
- HY-133535
-
|
PA-JF646-NHS
|
Dyes
|
|
PA Janelia Fluor® 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag ® and SNAP-tag ®. PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λExcitation/emission~650/664 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-110210
-
|
BODIPY FL,SE
|
Fluorescent Dyes/Probes
|
|
BODIPY-FL NHS ester (BODIPY FL, SE) is an amine-reactive fluorescent probe. The maximum excitation/emission values are 502/511 nm. BODIPY-FL NHS ester can be used to synthesize protease substrates .
|
- HY-D1872
-
|
|
Fluorescent Dyes/Probes
|
|
800CW NHS ester is a near infrared probe that can be used for labeling lysine residues (λmax=776 nm) .
|
- HY-133536
-
|
PA-JF549-NHS
|
Dyes
|
|
PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D1119A
-
|
|
Fluorescent Dyes/Probes
|
|
AF647-NHS ester (tripotassium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
- HY-D1119B
-
|
|
Fluorescent Dyes/Probes
|
|
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
- HY-135415
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5.5 NHS ester chloride is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
- HY-D0923
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3.5 NHS ester is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .
|
- HY-D1730A
-
|
|
Fluorescent Dyes/Probes
|
|
AF488 NHS ester TEA is an amine specific fluorescence probe (λem=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
- HY-135414B
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
- HY-D1352A
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
- HY-D2157
-
|
Coumarin 343-aminohexanoic acid-NHS ester
|
Fluorescent Dyes/Probes
|
|
Coumarin 343 X NHS ester is a homologue of Coumarin 343 (HY-W267364). Coumarin 343 is a hydrophilic fluorescent probe for use in microfluids.
|
- HY-D1661
-
|
|
Fluorescent Dyes/Probes
|
|
BDP 564/570 NHS ester is a lypophilic orange fluorescein dye, can be used for the labeling of amine containing biomolecules, including amine-modified oligonucleotides.
|
- HY-D0923A
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3.5 NHS ester TEA is a reactive dye for the labeling of amino groups in peptides, proteins, and oligonucleotides .
|
- HY-135415A
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5.5 NHS ester chloride TEA is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
- HY-D2175
-
|
|
Fluorescent Dyes/Probes
|
|
AF 555 NHS ester is a bright, orange-red fluorescence probe. AF 555 NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. AF 555 exhibits average excitation wavelengths under green laser and red laser of 510 nm and 610 nm, respectively .
|
- HY-D0799A
-
|
|
Dyes
|
|
Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
|
- HY-D1041
-
|
ICG NHS ester
|
Fluorescent Dyes/Probes
|
|
ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
|
- HY-D1611
-
|
|
Fluorescent Dyes/Probes
|
|
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .
|
- HY-D1974
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 610 NHS-Ester is an activated ester derivative of ATTO 610, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 616/633 nm.
|
- HY-D1979
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 725 NHS-Ester is an activated ester derivative of ATTO 725, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
- HY-D1983
-
|
|
Fluorescent Dyes/Probes
|
|
ATTO 620 NHS-Ester is an activated ester derivative of ATTO 620, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 620/642 nm.
|
- HY-D1849
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.
|
- HY-D1496
-
|
|
Fluorescent Dyes/Probes
|
|
Fluorescent Red Mega 485 NHS-ester is an amine conjugating fluorescent biolabel that can be used to label proteins .
|
- HY-D2189
-
|
IRDye 700DX NHS ester
|
Dyes
|
|
IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
|
- HY-D1692
-
|
|
Fluorescent Dyes/Probes
|
|
BODIPY 650/665 NHS ester is bright, far-red fluorescent dye that can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules . Ex / Em = 646 / 660 nm
|
- HY-D2096
-
|
|
Dyes
|
|
Alexa fluor 647 NHS ester can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
- HY-D1322
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5.5 NHS ester tetrafluoroborate belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
- HY-112498
-
|
Cyanine3 NHS ester
|
Fluorescent Dyes/Probes
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D1756
-
|
|
Fluorescent Dyes/Probes
|
|
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.
|
- HY-D1232
-
|
|
Dyes
|
|
BDP TMR NHS ester is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2328
-
|
Alexa Fluor 680 succinimidyl ester
|
Dyes
|
|
Alexa Fluor 680 NHS ester is a near-infrared (NIR) fluorescent dye. The Alexa Fluor 680 group has an absorption maximum at 679 nm and an emission maximum at 720 nm .
|
- HY-D1800
-
|
VF 680 SE
|
Fluorescent Dyes/Probes
|
|
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1801
-
|
VF 488 SE
|
Dyes
|
|
Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1790
-
|
VF 640 SE
|
Dyes
|
|
Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1802
-
|
VF 425 SE
|
Dyes
|
|
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1803
-
|
VF 565 SE
|
Dyes
|
|
Vari Fluor 565 SE (VF 565 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=563 nm/594 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1797
-
|
VF 660 SE
|
Dyes
|
|
Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1798
-
|
VF 350 SE
|
Dyes
|
|
Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1799
-
|
VF 568 SE
|
Dyes
|
|
Vari Fluor 568 SE (VF 568 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=573 nm/595 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1791
-
|
VF 750 SE
|
Dyes
|
|
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1792
-
|
VF 555 SE
|
Dyes
|
|
Vari Fluor 555 SE (VF 555 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=550 nm/561 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1794
-
|
VF 405 SE
|
Dyes
|
|
Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1795
-
|
VF 532 SE
|
Dyes
|
|
Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1796
-
|
VF 594 SE
|
Dyes
|
|
Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D0049
-
|
6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester
|
Oligonucleotide Labeling
|
|
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .
|
- HY-D1388
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D1223
-
|
|
Dyes
|
|
AF488 NHS ester diTEA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
- HY-110212
-
|
BODIPY TR-X NHS Ester
|
Protein Labeling
|
|
BODIPY TR-X (BODIPY TR-X NHS Ester) is a potent fluorescent dye. BODIPY TR-X can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, red fluorescent light. (λex=545 nm, λem=560 nm) .
|
- HY-D1596
-
|
Cy3.5 NHS ester chloride; Cy 3.5 chloride
|
Fluorescent Dyes/Probes
|
|
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
- HY-131026
-
|
JF635, SE; JF635, NHS
|
Dyes
|
|
Janelia Fluor® 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D0819A
-
|
Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt
|
Fluorescent Dyes/Probes
|
|
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
|
- HY-D1596A
-
|
Cy3.5 NHS ester bromide; Cy 3.5 bromide
|
Fluorescent Dyes/Probes
|
|
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
- HY-D0819
-
CY5-SE
Maximum Cited Publications
15 Publications Verification
Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
|
Fluorescent Dyes/Probes
|
|
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm):649, Emission (nm): 670.
|
- HY-138658
-
|
JF526, SE; JF526, NHS
|
Fluorescent Dyes/Probes
|
|
Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D0925
-
|
Cyanine5.5 NHS ester
|
Fluorescent Dyes/Probes
|
|
Cy5.5-SE (Cyanine5.5 NHS ester) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
- HY-131025
-
|
JF585, SE; JF585, NHS
|
Fluorescent Dyes/Probes
|
|
Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D0925B
-
|
Cyanine5.5 NHS ester TEA
|
Fluorescent Dyes/Probes
|
|
Cy5.5-SE TEA (Cyanine5.5 NHS ester TEA) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
- HY-D1106
-
|
|
Fluorescent Dyes/Probes
|
|
BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
|
- HY-D0823
-
|
Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester
|
Protein Labeling
|
|
Storage: protect from light.
|
- HY-D1906
-
|
|
Fluorescent Dyes/Probes
|
|
CellTracker Green BODIPY (compound 31) is a green fluorescent dye that acts as an intracellular environmental tracer .
|
- HY-D2309
-
|
|
Dyes
|
|
IRDye700Dx (IRDye 700DX NHS ester) Maleimide is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
|
- HY-D1111
-
|
AFDye 568 NHS Ester
|
Fluorescent Dyes/Probes
|
|
TFAX 568, SE is an orange fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 568, SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
|
- HY-D1658
-
|
|
Fluorescent Dyes/Probes
|
|
BDP 581/591 amine hydrochloride is a BODIPY dye linker. BDP 581/591 is a universal, photostable fluorophore. The addition of the amine group allows for the compound to react with carboxylic acids, activated NHS esters and other carbonyl groups .
|
- HY-D0048
-
|
5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester
|
Fluorescent Dyes/Probes
|
|
5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability.
|
- HY-131030
-
|
JF669, SE; JF669, NHS
|
Fluorescent Dyes/Probes
|
|
Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-130735
-
|
JF646, SE; JF646, NHS
|
Fluorescent Dyes/Probes
|
|
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-130736
-
|
JF549, SE; JF549, NHS
|
Fluorescent Dyes/Probes
|
|
Janelia Fluor® 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-131020
-
|
JF525, SE; JF525, NHS
|
Fluorescent Dyes/Probes
|
|
Janelia Fluor 525, SE (JF525, SE) is a yellow fluorescent dye (Ex = 525 nm; Em = 549 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D1085
-
|
|
Fluorescent Dyes/Probes
|
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
- HY-D1372
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
- HY-D1372A
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
- HY-D1363
-
|
|
Fluorescent Dyes/Probes
|
|
BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .
|
- HY-42972G
-
|
|
Fluorescent Dye
|
|
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690) . DBCO-acid is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
| Cat. No. |
Product Name |
Type |
-
- HY-136304
-
|
|
Drug Delivery
|
|
NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecule. NHS-PEG1-SS-PEG1-NHS can be used in proteins liposomes or nanoparticles .
|
-
- HY-W441011
-
|
|
Drug Delivery
|
|
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
|
-
- HY-150241
-
|
|
Drug Delivery
|
|
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
|
-
- HY-158072
-
|
|
Chelators
|
|
DOTAM-NHS-esteris a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester can be used for conjugation of peptides and radionuclides.
|
-
- HY-W437745
-
|
|
Biochemical Assay Reagents
|
|
Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .
|
-
- HY-W777012
-
|
|
Cell Assay Reagents
|
|
Acridinium C2 NHS ester is a chemiluminescent label that is active for the development of protein and nucleic acid probes. Acridinium C2 NHS ester can be used in bioanalysis and diagnostics to provide highly sensitive detection solutions. Acridinium C2 NHS ester is widely used in medical research, especially in the monitoring and analysis of biomolecules.
|
-
- HY-128890A
-
|
|
Chelators
|
|
DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.
|
-
- HY-163792
-
-
- HY-W440704
-
|
|
Carbohydrates
|
|
Cholesterol-PEG-NHS (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 5000) can be used in drug delivery research .
|
-
- HY-W440697
-
|
|
Drug Delivery
|
|
Cholesterol-PEG-NHS (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 1000) can be used in drug delivery research .
|
-
- HY-W440702
-
|
|
Drug Delivery
|
|
Cholesterol-PEG-NHS (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 2000) can be used in drug delivery research .
|
-
- HY-W440703
-
|
|
Drug Delivery
|
|
Cholesterol-PEG-NHS (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 3400) can be used in drug delivery research .
|
-
- HY-W544595
-
-
- HY-W441013
-
|
|
Drug Delivery
|
|
DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.
|
-
- HY-W143136
-
-
- HY-W441014
-
|
DSPE-PEG2000-NHS
|
Drug Delivery
|
|
DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-136158A
-
|
Sulfo-EMCS
|
Drug Delivery
|
|
6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W441015A
-
|
|
Drug Delivery
|
|
DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-W441012
-
|
|
Drug Delivery
|
|
DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-W123004
-
|
N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid
|
Biochemical Assay Reagents
|
|
PEG NHS ester disulfide (N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid) is a biochemical reagent.
|
-
- HY-155909
-
|
mPEG-SC (MW 3400); mPEG-Succinimidyl ester (MW 3400)
|
Drug Delivery
|
|
m-PEG-NHS ester (MW 3400) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909A
-
|
mPEG-SC (MW 1000); mPEG-Succinimidyl ester (MW 1000)
|
Drug Delivery
|
|
m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909B
-
|
mPEG-SC (MW 550); mPEG-Succinimidyl ester (MW 550)
|
Drug Delivery
|
|
m-PEG-NHS ester (MW 550) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909C
-
|
mPEG-SC (MW 350); mPEG-Succinimidyl ester (MW 350)
|
Drug Delivery
|
|
m-PEG-NHS ester (MW 350) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-W591424
-
|
mPEG-SC (MW 2000); mPEG-Succinimidyl ester (MW 2000)
|
Drug Delivery
|
|
m-PEG-NHS ester (MW 2000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-140698
-
|
mPEG-SC (MW 5000); mPEG-Succinimidyl ester (MW 5000)
|
Drug Delivery
|
|
m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140699
-
|
mPEG-SC (MW 10000); mPEG-Succinimidyl ester (MW 10000)
|
Drug Delivery
|
|
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140700
-
|
mPEG-SC (MW 20000); mPEG-Succinimidyl ester (MW 20000)
|
Drug Delivery
|
|
m-PEG-NHS ester (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W011412
-
|
|
Biochemical Assay Reagents
|
|
TSTU is able to converse carboxylic acid to the corresponding N-hydroxysuccinimidyl (NHS) ester, and is utilized as coupling reagent in peptide chemistry .
|
-
- HY-W440926
-
|
|
Drug Delivery
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-W440928
-
|
|
Drug Delivery
|
|
DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.
|
-
- HY-D0975
-
|
|
Biochemical Assay Reagents
|
|
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
|
-
- HY-140677
-
|
mPEG-NH2 (MW 5000)
|
Drug Delivery
|
|
mPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies .
|
-
- HY-42972G
-
|
|
Biochemical Assay Reagents
|
|
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690) . DBCO-acid is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P6021A
-
|
|
|
Others
|
|
HBpep-SP TFA is the TFA salt form of HBpep-SP (HY-P6021). HBpep-SP TFA is utilized for delivery and release of proteins, peptides and mRNA .
|
-
- HY-P6020A
-
|
|
Peptides
|
Others
|
|
HBpep-SA is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines .
|
-
- HY-P6020B
-
|
|
Peptides
|
Others
|
|
HBpep-SA acetate is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA acetate is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA acetate can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines .
|
-
- HY-P6020
-
|
|
Peptides
|
Others
|
|
HBpep-SA is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines .
|
-
- HY-P6021
-
|
|
Peptides
|
Others
|
|
HBpep-SP is a peptide. HBpep-SP can be used for delivery and release of proteins .
|
-
- HY-K0227
-
|
|
|
MCE NHS Magnetic Beads (200 nm, 10 mg/mL) contain N-hydroxysuccinimide (NHS) functional groups, which react with primary amines on proteins or
other molecules to form stable amide linkages，can covalently immobilize proteins for the affinity purification of antibodies, antigens and other
biomolecules.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P99239
-
|
HUJ-591
|
PSMA
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 ( 177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-151727
-
|
|
|
Tetrazine
|
|
Norbornene-NHS is a click chemistry reagent. Norbornene-NHS is a dienophile for conjugation via copper-free Click reaction with tetrazines .
|
-
- HY-141170
-
|
|
|
TCO
ADC Synthesis
PROTAC Synthesis
|
|
TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126885
-
|
|
|
ADC Synthesis
PROTAC Synthesis
DBCO
|
|
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-126974
-
|
|
|
ADC Synthesis
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130376
-
|
|
|
PROTAC Synthesis
ADC Synthesis
Alkynes
|
|
Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141166A
-
|
|
|
TCO
|
|
(S,E)-TCO2-PEG3-NHS ester is NH2 reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .
|
-
- HY-160773
-
|
|
|
DBCO
|
|
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-151758
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG12-NHS ester is a click chemistry reagent containing an azide group. Methyltetrazine-PEG12-NHS ester reacts with compounds containing TCO to form stable covalent bonds .
|
-
- HY-130381
-
|
|
|
PROTAC Synthesis
Alkynes
ADC Synthesis
|
|
Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130385
-
|
|
|
ADC Synthesis
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130388
-
|
|
|
PROTAC Synthesis
ADC Synthesis
Alkynes
|
|
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126511
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126512
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140273
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140271
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140272
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140274
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133439
-
|
|
|
BCN
PROTAC Synthesis
|
|
BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138744
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138734
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126513
-
|
|
|
Alkynes
ADC Synthesis
|
|
Propargyl-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126516
-
|
|
|
Alkynes
ADC Synthesis
|
|
Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141167A
-
|
|
|
TCO
PROTAC Synthesis
|
|
TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-111456
-
|
|
|
DBCO
ADC Synthesis
PROTAC Synthesis
|
|
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141166
-
|
|
|
TCO
|
|
TCO-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141168
-
|
|
|
TCO
|
|
TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141169
-
|
|
|
TCO
|
|
TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141272
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141171
-
|
|
|
TCO
|
|
TCO-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141271
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141269
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141270
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-145090
-
|
|
|
DBCO
ADC Synthesis
PROTAC Synthesis
|
|
DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141167B
-
|
|
|
ADC Synthesis
TCO
|
|
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-130184
-
|
|
|
ADC Synthesis
Azide
PROTAC Synthesis
|
|
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130474
-
|
|
|
PROTAC Synthesis
ADC Synthesis
Azide
|
|
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-156313
-
|
|
|
Tetrazine
|
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156476
-
|
|
|
Tetrazine
|
|
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156490
-
|
|
|
Tetrazine
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156491
-
|
|
|
Tetrazine
|
|
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-140068
-
|
|
|
BCN
PROTAC Synthesis
|
|
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140275
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140070
-
|
|
|
PROTAC Synthesis
BCN
|
|
endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140069
-
|
|
|
BCN
PROTAC Synthesis
|
|
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140276
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133375
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-NHCO-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138756
-
|
|
|
DBCO
PROTAC Synthesis
|
|
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130551
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133371
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-NHCO-C4-NHS ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-C4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-42973
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-141165
-
|
|
|
PROTAC Synthesis
TCO
|
|
TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-140139
-
|
|
|
Alkynes
ADC Synthesis
|
|
PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-156323
-
|
|
|
BCN
|
|
BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-156324
-
|
|
|
BCN
|
|
BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-140759
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140758
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG9-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140757
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140756
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140764
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140761
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG16-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG16-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140762
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG24-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140760
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-138463
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG36-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG36-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-138707
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG7-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-151835
-
|
|
|
DBCO
|
|
DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
|
- HY-140755
-
|
|
|
Azide
PROTAC Synthesis
|
|
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Aeide-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W096079
-
|
|
|
BCN
|
|
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-151827
-
|
|
|
DBCO
|
|
DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
|
- HY-151686
-
|
|
|
Tetrazine
|
|
Bz-(Me)Tz-NHS is a click chemistry reagent containing an methyltetrazine group. Bz-(Me)Tz-NHS is 3rd generation Click-Linker for Cu-free click conjugation .
|
- HY-140141
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133479
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-C3-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-141169A
-
|
|
|
TCO
|
|
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-151698
-
|
|
|
TCO
|
|
TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-123687
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-135973
-
|
|
|
ADC Synthesis
BCN
|
|
BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-126908
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130283
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136032
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136033
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-126520
-
|
|
|
Azide
ADC Synthesis
|
|
N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-126521
-
|
|
|
Azide
ADC Synthesis
|
|
N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-126522
-
|
|
|
Azide
ADC Synthesis
|
|
N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-126523
-
|
|
|
ADC Synthesis
Azide
|
|
N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-115524
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry . DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-151698B
-
|
|
|
TCO
|
|
(R,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
- HY-151698A
-
|
|
|
TCO
|
|
(S,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
- HY-140142
-
|
|
|
Azide
PROTAC Synthesis
|
|
PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Azido-PEG11-NHS carbonate ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-141268
-
|
|
|
Tetrazine
|
|
Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-135959
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-NH-PEG7-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NH-PEG7-C2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-130390
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140067
-
|
|
|
BCN
|
|
endo-BCN-PEG2-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
- HY-140767
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG8-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-148840
-
|
|
|
DBCO
|
|
Sulfo DBCO-PEG3-NHS ester is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .
|
- HY-130931
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-NH-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-133539
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-C8-amido-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-115545
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC) . DBCO-NHS ester 3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-154802
-
|
|
|
TCO
|
|
TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-164085
-
|
|
|
Azide
|
|
Azide-C3-NHCO-C3-NHS ester is utilized as a linker in chemical synthesis, especially when rapid and specific ligation via click chemistry is required .
|
- HY-130312
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140582
-
|
|
|
DBCO
PROTAC Synthesis
|
|
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133412
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133413
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-126526
-
|
|
|
Azide
ADC Synthesis
|
|
N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-126528
-
|
|
|
Azide
ADC Synthesis
|
|
N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-130109
-
|
|
|
ADC Synthesis
Azide
|
|
N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140585
-
|
|
|
DBCO
PROTAC Synthesis
|
|
N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-DBCO-N-bis(PEG2-C2-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-151742
-
|
|
|
TCO
|
|
Norbornene-methyl-NHS is a click chemistry reagent containing a TCO group. Dienophile for conjugation via Diels-Alder-reaction, i.e. copper-free click reaction with tetrazines .
|
- HY-140766
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-138350
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG10-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-133431
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-SS-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140102
-
|
|
|
ADC Synthesis
Azide
|
|
Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-141172
-
|
|
|
TCO
|
|
TCO-PEG2-Sulfo-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141172A
-
|
|
|
TCO
|
|
TCO-PEG2-Sulfo-NHS ester sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-140763
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-136040
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133466
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-126524
-
|
|
|
ADC Synthesis
Azide
|
|
N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-Ph-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140765
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W035129
-
|
|
|
BCN
|
|
endo-BCN-NHS carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-126514
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-O-C1-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-126515
-
|
|
|
Alkynes
ADC Synthesis
|
|
Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140561
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140560
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140559
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W096149
-
|
|
|
BCN
|
|
exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-133583
-
|
|
|
Alkynes
ADC Synthesis
|
|
Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-O-C1-amido-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-151769
-
|
|
|
Labeling and Fluorescence Imaging
TCO
|
|
TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-140866
-
|
|
|
PROTAC Synthesis
Azide
|
|
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140768
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-O-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-126525
-
|
|
|
Azide
ADC Synthesis
|
|
4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-135966
-
|
|
|
Azide
ADC Synthesis
|
|
Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG3-SS-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-141048
-
|
|
|
PROTAC Synthesis
Azide
|
|
N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140770
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-aminoacetic acid-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140865
-
|
|
|
PROTAC Synthesis
Azide
|
|
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-24592
-
|
|
|
TCO
|
|
(S,E)-Cyclooct-2-enol is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
- HY-42972
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690) . DBCO-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W441011
-
|
|
|
Phospholipids
|
|
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
|
-
- HY-W440927
-
|
|
|
Pegylated Lipids
|
|
Stearic acid-PEG-NHS, MW 2,000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.
|
-
- HY-W441014
-
|
DSPE-PEG2000-NHS
|
|
Pegylated Lipids
|
|
DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-W441016
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-NHS, MW 5000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
|
-
- HY-RS09290
-
|
|
|
siRNAs
Pre-designed siRNA Sets
|
|
NHS Human Pre-designed siRNA Set A contains three designed siRNAs for NHS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
- HY-150241
-
|
|
|
Phospholipids
|
|
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
|
-
- HY-W441013
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.
|
-
- HY-W441015A
-
|
|
|
Pegylated Lipids
|
|
DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-W441012
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-155909
-
|
mPEG-SC (MW 3400); mPEG-Succinimidyl ester (MW 3400)
|
|
Polymers
|
|
m-PEG-NHS ester (MW 3400) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909A
-
|
mPEG-SC (MW 1000); mPEG-Succinimidyl ester (MW 1000)
|
|
Polymers
|
|
m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909B
-
|
mPEG-SC (MW 550); mPEG-Succinimidyl ester (MW 550)
|
|
Polymers
|
|
m-PEG-NHS ester (MW 550) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909C
-
|
mPEG-SC (MW 350); mPEG-Succinimidyl ester (MW 350)
|
|
Polymers
|
|
m-PEG-NHS ester (MW 350) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-W591424
-
|
mPEG-SC (MW 2000); mPEG-Succinimidyl ester (MW 2000)
|
|
Polymers
|
|
m-PEG-NHS ester (MW 2000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-157745
-
|
mPEG-SC (MW 40000); mPEG-Succinimidyl ester (MW 40000)
|
|
Polymers
|
|
m-PEG-NHS ester (MW 40000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects .
|
-
- HY-W441005
-
|
|
|
Phospholipids
|
|
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.
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- HY-W440706
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Pegylated Lipids
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Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
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- HY-W440945
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Pegylated Lipids
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Stearic acid-PEG-amine, MW 2000 is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.
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- HY-145547
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14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine
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Phospholipids
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1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .
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