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Results for "

anti-fungal activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fungal (535) Acetolactate Synthase (ALS) (1) Akt (2) AMPK (1) Amylases (1) Antibiotic (81) Apoptosis (62) Atg8/LC3 (2) ATP Synthase (1) Autophagy (27) Bacterial (168) Bcl-2 Family (4) Biochemical Assay Reagents (3) Calcineurin (1) Cannabinoid Receptor (2) Caspase (2) Cholinesterase (ChE) (1) COX (3) Cytochrome P450 (23) Dihydrofolate reductase (DHFR) (1) DNA/RNA Synthesis (4) Dopamine β-hydroxylase (1) E1/E2/E3 Enzyme (2) Endogenous Metabolite (25) ERK (2) Estrogen Receptor/ERR (1) FAAH (1) FATP (1) Fatty Acid Synthase (FASN) (2) Ferroptosis (14) FKBP (1) Fluorescent Dye (1) GABA Receptor (2) Glucosidase (1) GPR55 (2) GSK-3 (1) HBV (2) HCV (1) HDAC (2) Histone Acetyltransferase (1) HIV (9) HIV Integrase (2) HMG-CoA Reductase (HMGCR) (1) HSP (2) HSV (2) IFNAR (1) IGF-1R (1) Influenza Virus (11) Isotope-Labeled Compounds (16) JAK (3) JNK (1) Leukotriene Receptor (1) Lipase (1) Lipoxygenase (3) LRRK2 (1) MDM-2/p53 (3) Microtubule/Tubulin (5) Mitochondrial Metabolism (5) Mitophagy (2) MMP (1) Monoamine Oxidase (1) mTOR (1) Myosin (1) Necroptosis (2) NF-κB (10) NO Synthase (1) NOD-like Receptor (NLR) (2) Oxidative Phosphorylation (2) p38 MAPK (4) p62 (2) Parasite (31) PARP (1) PD-1/PD-L1 (4) Phosphatase (1) Phospholipase (2) Photosystem II (1) PI3K (5) PPAR (8) Reactive Oxygen Species (16) Reverse Transcriptase (1) ROS Kinase (1) RSV (2) SARS-CoV (6) Ser/Thr Protease (2) Src (1) Succinate Dehydrogenase (6) Tau Protein (2) Thrombopoietin Receptor (2) TNF Receptor (2) Topoisomerase (3) TRP Channel (2) Tyrosinase (1) VEGFR (2) Virus Protease (4) Wee1 (1) Wnt (2) Xanthine Oxidase (1)
By Research Areas:	Cancer (147) Cardiovascular Disease (14) Endocrinology (3) Infection (571) Inflammation/Immunology (116) Metabolic Disease (26) Neurological Disease (20)
Oligonucleotides:	Nucleosides and their Analogs (1)

617

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

270

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: Fungal

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148054

Antifungal agent 36	Fungal	Infection
Antifungal agent 36 is a potent *anti-fungal* agent. Antifungal agent 36 shows anti-fungal activity for Basidiomycetes .

HY-123777

VT-1598	Fungal	Infection Inflammation/Immunology
VT-1598 is an orally active and selective *fungal* inhibitor targeting CYP51. VT-1598 shows anti-fungal activity against Candida auris . VT-1598 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N0126

Xanthone 1 Publications Verification	Bacterial Influenza Virus Fungal Apoptosis	Infection Inflammation/Immunology Cancer
Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities .

HY-B1747

Pyrithione 3 Publications Verification	Bacterial Fungal	Infection
Pyrithione, a Transition metal complexe, is a zinc ionophore that causes increased zinc levels within mammalian cells. Pyrithione has potent bactericidal and *anti-fungal* activity .

HY-N6656

6-Hydroxycoumarin	Fungal Bacterial	Inflammation/Immunology Cancer
6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity .

HY-N0363

(+)-Columbianetin (S)-Columbianetin	Fungal	Infection Inflammation/Immunology
(+)-Columbianetin is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N13284

13-Hydroxy-9-octadecenoic acid	Fungal	Infection
13-Hydroxy-9-octadecenoic acid is a hydroxy unsaturated fatty acid (HUFA) that has anti-fungal activity .

HY-19584

Variotin	Fungal	Infection
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .

HY-N0334

(+)-Magnoflorine Magnoflorine; α-Magnoflorine; Thalictrine	Fungal	Infection Metabolic Disease
(+)-Magnoflorine (Magnoflorine), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm . (+)-Magnoflorine has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-138145

8-Acetyl-7-hydroxycoumarin	Fungal Bacterial	Infection
8-Acetyl-7-hydroxycoumarin is a coumarin-like compound found in Mexican patchouli (Tagetes lucida) that has anti-bacterial and anti-fungal activities .

HY-N0535

(+)-Magnoflorine chloride Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride	Fungal	Infection Metabolic Disease
Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm . Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-16589

Oligomycin A 30+ Cited Publications MCH 32	ATP Synthase Fungal Antibiotic	Infection Cancer
Oligomycin A (MCH 32), created by Streptomyces, acts as a mitochondrial F₀F₁-ATPase inhibitor, with a K_i of 1 μM; Oligomycin A shows anti-fungal activity.

HY-N0363A

(+)-Columbianetin acetate (S)-Columbianetin acetate	Fungal	Infection Inflammation/Immunology
(S)-Columbianetin acetate is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N2014

Verbenalin 1 Publications Verification	SARS-CoV	Infection Inflammation/Immunology
Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury .

HY-N0334A

(+)-Magnoflorine iodide Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide	Fungal	Infection Metabolic Disease
(+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm . (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-W097994

DHMB 2,3-Dihydroxy-4-methoxybenzaldehyde	Fungal	Infection Inflammation/Immunology
DHMB (2,3-Dihydroxy-4-methoxybenzaldehyde) is a small organic molecule with *anti-fungal* and anti-inflammatory activity. DHMB has protective effect on intestinal epithelial cells .

HY-N8105

Protoneogracillin	Fungal	Infection Cancer
Protoneogracillin, a furostanol glycoside, shows anti-fungal activity against the plant pathogenic fungus P.oryzae (MMDC=94.0 μM) and cytotoxic activity on K562 cancer cells (IC₅₀=6.6 μM) .

HY-129055

Isoeleutherin	Fungal	Inflammation/Immunology
Isoeleutherin is a naphthopyran derivative isolated from E. americana Merr. Et Heyne with anti-fungal, anti-viral, and anti-tumor activities. Isoeleutherin plays an important role in selective modulation of T helper cell-mediated immune responses .

HY-109706

(Rac)-CPI-098	Bacterial Fungal	Infection
(Rac)-CPI-098 shows antibacterial activity. (Rac)-CPI-098 exhibits superior anti-fungal activity against Monascus ruber, better activity against Aspergillus fumigates, good activity against Aspergillus niger and Aspergillus parasites and moderate activity against Candida albicans .

HY-N0889

Ginkgetin 4 Publications Verification	COX Wnt Apoptosis Autophagy	Inflammation/Immunology Cancer
Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

HY-N0363R

(+)-Columbianetin (Standard)	Fungal	Infection Inflammation/Immunology
(+)-Columbianetin (Standard) is the analytical standard of (+)-Columbianetin. This product is intended for research and analytical applications. (+)-Columbianetin is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N0535R

(+)-Magnoflorine chloride (Standard)	Fungal	Infection Metabolic Disease
(+)-Magnoflorine (chloride) (Standard) is the analytical standard of (+)-Magnoflorine (chloride). This product is intended for research and analytical applications. Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm . Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-N0363AR

(+)-Columbianetin acetate (Standard)	Fungal	Infection Inflammation/Immunology
(+)-Columbianetin acetate (Standard) is the analytical standard of (+)-Columbianetin acetate. This product is intended for research and analytical applications. (S)-Columbianetin acetate is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N2014R

Verbenalin (Standard)	SARS-CoV	Infection Inflammation/Immunology
Verbenalin (Standard) is the analytical standard of Verbenalin. This product is intended for research and analytical applications. Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury .

HY-N0393

Glabridin 3 Publications Verification	PPAR Reactive Oxygen Species Bacterial	Infection Inflammation/Immunology Cancer
Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ, with an EC₅₀ of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .

HY-17643

Oteseconazole VT-1161	Fungal Cytochrome P450	Infection
Oteseconazole (VT-1161) is a potent and orally active *anti-fungal* agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (K_d ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .

HY-126810

NP213	Fungal	Infection
NP213 is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has *anti-fungal* activities. NP213 targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 is effective and well-tolerated in resolving nail fungal infections .

HY-N6635

trans-Nerolidol	Fungal	Infection Cancer
trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity .

HY-N7030

5,7,3',4'-Tetramethoxyflavone	Fungal Parasite Bacterial	Infection
5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling .

HY-130703

5-Dehydroepisterol	Fungal	Infection
5-Dehydroepisterol is an episterol derivative and an intermediate in steroid biosynthesis. 5-Dehydroepisterol can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase. 5-Dehydroepisterol has *anti-fungal* activities .

HY-P2365

Histatin-8	Fungal	Infection
Histatin-8 is a part of the Histatin-3 central sequence and is known as hemagglutination-inhibiting peptide. Histatin-8 is a potent *anti-fungal* peptide. Histatin-8 shows antimicrobial activity against yeast strains. Histatin-8 can be used for oral thrush research .

HY-13557

Ascomycin 5+ Cited Publications Immunomycin; FR-900520; FK520	FKBP Parasite Fungal Antibiotic	Infection Neurological Disease Inflammation/Immunology
Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-126810A

NP213 TFA	Fungal	Infection
NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has *anti-fungal* activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .

HY-N6869

Dehydroabietic acid	Antibiotic PPAR Bacterial Fungal	Infection Metabolic Disease Inflammation/Immunology Cancer
Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .

HY-N0126R

Xanthone (Standard) 1 Publications Verification	Bacterial Influenza Virus Fungal Apoptosis	Infection Inflammation/Immunology Cancer
Xanthone (Standard) is the analytical standard of Xanthone. This product is intended for research and analytical applications. Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities .

HY-N0889R

Ginkgetin (Standard)	COX Wnt Apoptosis Autophagy	Inflammation/Immunology Cancer
Ginkgetin (Standard) is the analytical standard of Ginkgetin. This product is intended for research and analytical applications. Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

HY-123777A

VT-1598 tosylate	Cytochrome P450	Infection
VT-1598 tosylate is an orally active and selective *fungal* inhibitor targeting CYP51. VT-1598 tosylate shows anti-fungal activity against C. auris . VT-1598 (tosylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N0393R

Glabridin (Standard)	PPAR Reactive Oxygen Species Bacterial	Infection Inflammation/Immunology Cancer
Glabridin (Standard) is the analytical standard of Glabridin. This product is intended for research and analytical applications. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC₅₀ of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .

HY-17643R

Oteseconazole (Standard)	Fungal Cytochrome P450	Infection
Oteseconazole (Standard) is the analytical standard of Oteseconazole. This product is intended for research and analytical applications. Oteseconazole (VT-1161) is a potent and orally active *anti-fungal* agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (K_d ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .

HY-129555

Surfactin 5 Publications Verification	Bacterial HSV Antibiotic	Infection
Surfactin is a potent cyclic lipopeptide biosurfactants consists of four isomers (Surfactin A, B, C and D), which mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects . Surfactin also has antiviral activity against a variety of enveloped viruses .

HY-108485

Damnacanthal	Src Apoptosis Fungal	Infection Inflammation/Immunology Cancer
Damnacanthal is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56 ^lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 ^lck autophosphorylation and phosphorylation of exogenous substrates with IC₅₀s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity against *Candida albicans* .

HY-N0662R

Amentoflavone (Standard)	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N6635R

trans-Nerolidol (Standard)	Fungal	Infection Cancer
trans-Nerolidol (Standard) is the analytical standard of trans-Nerolidol. This product is intended for research and analytical applications. trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity .

HY-N6869R

Dehydroabietic acid (Standard)	Antibiotic PPAR Bacterial Fungal	Infection Metabolic Disease Inflammation/Immunology Cancer
Dehydroabietic acid (Standard) is the analytical standard of Dehydroabietic acid. This product is intended for research and analytical applications. Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .

HY-N7135

Tropolone	Tyrosinase Fungal	Metabolic Disease Inflammation/Immunology Cancer
Tropolone is a seven-membered non-benzenoid aromatic compound, which is the precursor of many Azulene derivatives. Tropolone is a potent mushroom tyrosinase inhibitor with an IC₅₀ value of 0.4 μM. Its inhibitory effect can be achieved by dialysis or excess CU ²⁺ Reversa. Tropolone exhibits broad anti-viral and anti-fungal activity and is synergistic upon co-treatment with nucleos(t)ide analog drugs. Tropolone is a promising candidate for research in osteosarcoma .

HY-10863

Anandamide 1 Publications Verification AEA	Cannabinoid Receptor PPAR TRP Channel GPR55 Fungal Tau Protein Endogenous Metabolite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential *anti-fungal* and *anti-inflammatory* activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis .

HY-B0914A

10-Undecenoic acid zinc salt 1 Publications Verification Zinc undecylenate	Fungal DNA/RNA Synthesis	Infection
10-Undecenoic acid zinc salt is a RNA-dependent RNA polymerase (RdRp) inhibitor, with an IC₅₀ of 1.13, 21.33 and 1.79 μM for WT-RdRp, D535ARdRp and D692A-RdRp, respectively. 10-Undecenoic acid zinc salt reduces infectious virus yield in Huh7 cells with an EC₅₀ of 7.43 μM. 10-Undecenoic acid zinc salt has anti-infective and anti-fungal activity. 10-Undecenoic acid zinc salt can be used for the research of Zika virus (ZIKV) .

HY-10863S

Anandamide-d8 AEA-d₈	Isotope-Labeled Compounds Cannabinoid Receptor PPAR Endogenous Metabolite Tau Protein GPR55 Fungal TRP Channel	Infection
Anandamide-d8 is a deuterated labeled Anandamide . Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential *anti-fungal* and *anti-inflammatory* activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis .

HY-146464

Antifungal agent 30	Fungal	Infection
Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51 .

Cat. No.	Product Name

HY-L002

Anti-Infection Compound Library

3,141 compounds

An infection occurs when another organism enters a person’s body and causes disease. The organisms that cause infections are very diverse and can include things like viruses, bacteria, fungi, and parasites. The immune system is an effective barrier against infectious agents.

MCE provides a unique collection of 3,141 anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities that can be used for drug screening and other research in anti-microbial area.

HY-L048

Antifungal Compound Library

380 compounds

The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is challenging because there are many similarities between fungal and human cells. The most common antifungal targets include fungal RNA synthesis and cell wall and membrane components, though new antifungal targets are being investigated. Nonetheless, fungi have developed resistance mechanisms, such as overexpression of efflux pump proteins, overexpression and changes in drug targets and biofilm formation, emphasizing the importance of discovering new antifungal drugs and therapies. Due to the limited antifungal arsenal, researchers have sought to improve treatment via different approaches, such as the combination of antifungal drugs, development of new formulations for antifungal agents and modifications to the chemical structures of traditional antifungals, etc.

MCE offers a unique collection of 380 compounds with validated antifungal activities. MCE antifungal compound library is an effective tool for drug repurposing screening, combination screening and biological investigation.

HY-L071

Alkaloids Library

547 compounds

Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds.

MCE designs a unique collection of 547 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

HY-L138

Heterocyclic Compound Library

6,133 compounds

Heterocyclic compounds are cyclic organic compounds which contain at least one hetero atom, the most common heteroatoms are nitrogen, oxygen ,and sulfur. Heterocycles are common in biology, featuring a wide range of structures from enzyme co-factors to amino acids and proteins. On the one hand, heterocycles are common structural units in approved drugs and in medicinal chemistry targets in the drug discovery process. In addition, heterocycles have been found as a key structure in medical chemistry and also they are frequently found in large percent of biomolecules such as vitamins, natural products ,and biologically active compounds including antifungal, anti-inflammatory, antibacterial, antioxidant, antiallergic, anti-HIV, antidiabetic, anticancer activity.

MCE offers a unique collection of 6,133 heterocyclic compounds which can be used for drug discovery for high throughput screening (HTS) and high content screening (HCS). MCE heterocyclic compound library is critical for drug discovery and development.

Cat. No.	Product Name	Type

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Fluorescent Dye

Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

Cat. No.	Product Name	Type

HY-138540

1-Dodecylimidazole 1 Publications Verification N-Dodecylimidazole	Cell Assay Reagents
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity .

HY-119445A

Sophorose monohydrate

2-O-beta-D-Glucopyranosyl-D-glucopyranose monohydrate

Carbohydrates

Sophorose (2-O-beta-D-Glucopyranosyl-D-glucopyranose) monohydrate is the disaccharide component of microbial glycolipids, which are often used as biosurfactants due to their hydrophobicity. Sophorolipids also exhibit antibacterial, antifungal, spermicidal, virucidal, and anticancer activities. In studies of Trichoderma reesei fermentation, sophorose monohydrate has been identified as a potent inducer of cellulase gene expression .

HY-D0837

Imidazole

2 Publications Verification

Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene

Cell Assay Reagents

Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG₂ and PGH₂) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL ^Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

HY-W008864

Lactose octaacetate β-Octaacetyllactose	Cell Assay Reagents
Lactose octaacetate shows mild to moderate antifungal activity against some fungi, but it has low or no activity against bacteria and yeast. Lactose octaacetate shows low cytotoxicity to MDBK cells, Hep-2 and MDCK cells. Lactose octaacetate has antiviral activity against PV-1 .

HY-119445

Sophorose

2-O-beta-D-Glucopyranosyl-D-glucopyranose

Carbohydrates

Sophorose is a disaccharide component of microbial glycolipids produced by yeast called sophorolipids. Due to their hydrophobic nature, sophorolipids are commonly used as biosurfactants. Sophorolipids also exhibit antibacterial, antifungal, spermicidal, virucidal, and anticancer activities. Sophorose has been identified as a potent inducer of cellulase gene expression in Trichoderma reesei fermentation studies.

HY-W037200

2,3,5-Tri-O-benzyl-D-ribose 2,3,5-Tri-O-benzyl-D-ribofuranose	Cell Assay Reagents
2,3,5-Tri-O-benzyl-D-ribose (Compound 1) is an effective inhibitor of Botrytis cinerea chitin synthase (CHS) with an IC₅₀ value of 1.8 μM. 2,3,5-Tri-O-benzyl-D-ribose exhibits antifungal activity and is able to inhibit the B. cinerea BD90 strain, with a MIC value of 190 μM .

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Biochemical Assay Reagents

HY-D0837R

Imidazole (Standard)

Cell Assay Reagents

Imidazole (Standard) is the analytical standard of Imidazole. This product is intended for research and analytical applications. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CLPro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

Cat. No.	Product Name	Target	Research Area

HY-126810A

NP213 TFA	Fungal	Infection
NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has *anti-fungal* activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .

HY-P1975

Aureobasidin A 2 Publications Verification Basifungin	Fungal Parasite	Infection Inflammation/Immunology
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has *antifungal* and antiparasitic activity .

HY-P2322

Iturin A 1 Publications Verification	Fungal	Infection
IturinA exhibits strong *antifungal* activity against pathogenic yeast and fungi. Iturin A interacts with the cytoplasmic membrane of the target cell forming ion conducting pores.

HY-P2365

Histatin-8	Fungal	Infection
Histatin-8 is a part of the Histatin-3 central sequence and is known as hemagglutination-inhibiting peptide. Histatin-8 is a potent *anti-fungal* peptide. Histatin-8 shows antimicrobial activity against yeast strains. Histatin-8 can be used for oral thrush research .

HY-P5572

Aurein 2.5	Antibiotic Fungal Bacterial	Infection
Aurein 2.5 is an antibiotic antimicrobial peptide. Aurein 2.5 has antibacterial and antifungal activity

HY-113560

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

HY-P0068

Aminocandin HMR 3270; IP960; NXL201	Fungal	Infection
Aminocandin (HMR 3270) is water-soluble *antifungal* agent of the echinocandin class with excellent activity against Aspergillus and Candida spp. .

HY-105267

LY 121019	Fungal Antibiotic	Infection
LY 121019 is a semi-synthetic *antifungal* antibiotic with strong anticandida activity with MIC₅₀ value of 0.625 μg/mL .

HY-P3917

LfcinB (20–30)	Bacterial	Infection
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

HY-P5696

Xenopsin precursor fragment	Bacterial Parasite Fungal	Infection
Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity .

HY-P5569

SP-B peptide	Fungal	Infection
SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against strains of Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus

HY-P5639

Gageotetrin A	Peptides	Infection
Gageotetrin A is an antimicrobial peptide derived from the marine bacterium Bacillus subtilis. Gageotetrin A has antifungal activity, but none toxic to numerous human cancer cells .

HY-P5729

LL-25	Fungal	Infection
LL-25 is a fragment of LL-37 (HY-P1222) but devoid of the immunomodulatory properties of LL-37. LL-25 has antifungal and candidacidal activity .

HY-P5701

EP2	Bacterial Fungal	Infection
EP2 is an antimicrobial peptide. EP2 has antibacterial and antifungal activities. EP2 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 11.4 μg/mL .

HY-P10410

AEC5	Fungal	Infection
AEC5 is a Lipopeptoid with antifungal activity against Cryptococcus neoformans. AEC5 has no observable cytotoxicity against human lung, liver, or red blood cells at the MIC value (6.3 μg/mL) for Cryptococcus neoformans .

HY-P5703

EP5-1	Bacterial Apoptosis Fungal	Infection
EP5-1 is an antimicrobial peptide. EP5-1 has antibacterial and antifungal activities. EP5-1 also shows antitumor activity against cancer cells, and induces cell apoptosis. EP5-1 has antiviral activity against pseudorabies virus (PRV) .

HY-P5016

CRAMP-18 (mouse)	Antibiotic Bacterial Fungal	Infection Cancer
CRAMP-18 (mouse) is an antibiotic peptide without hemolytic activity. CRAMP-18 (mouse) has good inhibitory activity against Gram-negative bacteria, such as S. typhimurium and P. aeruginosa. CRAMP-18 (mouse) has the potential to study antifungal, antibacterial and antitumor .

HY-P5702

EP3	Bacterial Apoptosis Fungal	Infection
EP3 is an antimicrobial peptide. EP3 has antibacterial and antifungal activities. EP3 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 12.85 μg/mL. EP3 also shows antitumor activity against cancer cells, and induces cell apoptosis .

HY-P5071

EcAMP3	Bacterial	Infection
EcAMP3 is a hairpin-like peptide. EcAMP3 has *antifungal* and antibacterial activity. EcAMPs precursor family contains seven identical cysteine motifs: C1XXXC2(11–13)C3XXXC4 .

HY-P10596

Lasioglossin-III	Bacterial Fungal	Infection Cancer
Lasioglossin-III is an antimicrobial peptide that can be isolated from the venom of wild bees. Lasioglossin-III has high antibacterial activity against Gram-positive and Gram-negative bacteria, antifungal activity and antitumor activity. Lasioglossin-III has certain cytotoxicity against three cancer cell lines (HeLa S3, CRC SW 480 and CCRF-CEM T) with IC₅₀ values of 4, 18 and 5 μM, respectively .

HY-P4370

Hepcidin-20 (human)	Bacterial Fungal	Infection
Hepcidin-20 (human) is a histidine-containing, cysteine-rich, β-sheet structured peptide. Hepcidin-20 (human) shows antifungal activity. Hepcidin-20 (human) inhibits biofilm formation and bacterial cell metabolism of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains .

HY-P1629

Temporin A	Bacterial Fungal Antibiotic	Infection
Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans) .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P3906

Melittin free acid	Fungal Apoptosis Phospholipase Reactive Oxygen Species	Infection
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .

HY-P2098

Alamethicin F 50	Antibiotic Bacterial Fungal	Infection
Alamethicin F 50 is an antibiotic. Alamethicin F 50 is composed of membrane-active peptide, containing 75% Alamethicin F 50/5 and 10% Alamethicin F 50/7. Alamethicin F 50 is exhibits antifungal and antibacterial activity by disrupting the integrity of microbial cell membranes, resulting in leakage of cell contents and death of the microorganisms. Alamethicin F 50 is able to reduce the surface tension of water, which can be used as a surfactant or detergent .

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

HY-P10281

RW3	Bacterial	Infection
RW3 is a small cationic hexapeptide with amphiphilic properties. RW3 targets the plasma membrane of bacteria and works by inhibiting cell respiration and cell wall synthesis. RW3 shows high biological activity against gram-positive bacteria and does not show significant cytotoxic or hemolytic effects in previous studies. RW3 quickly kills 97% of the initial colony forming units (CFU) within 10 minutes at twice the minimum inhibitory concentration (MIC). RW3 can be used in antimicrobial and antifungal studies .

Cat. No.	Product Name	Target	Research Area

HY-P9962

Efungumab	Fungal	Infection
Efungumab is a monoclonal antibody with *antifungal* activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0126

Xanthone 1 Publications Verification	Infection Structural Classification Xanthones Classification of Application Fields Guttiferae Source classification Phenols Garcinia mangostana Linn. Plants Inflammation/Immunology Disease Research Fields	Bacterial Influenza Virus Fungal Apoptosis
Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities .

HY-N6656

6-Hydroxycoumarin	Structural Classification Monophenols other families Classification of Application Fields Source classification Coumarins Phenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Fungal Bacterial
6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity .

HY-N0363

(+)-Columbianetin (S)-Columbianetin	Structural Classification Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Umbelliferae Seriphidium transiliense Inflammation/Immunology Disease Research Fields	Fungal
(+)-Columbianetin is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N0535

(+)-Magnoflorine chloride Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Aristolochiaceae Infection Alkaloids Piperidine Alkaloids other families Aristolochia debilis Sieb. et Zucc. Phenols Polyphenols Disease Research Fields	Fungal
Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm . Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-16589

Oligomycin A Maximum Cited Publications 31 Publications Verification MCH 32	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields	ATP Synthase Fungal Antibiotic
Oligomycin A (MCH 32), created by Streptomyces, acts as a mitochondrial F₀F₁-ATPase inhibitor, with a K_i of 1 μM; Oligomycin A shows anti-fungal activity.

HY-N0363A

(+)-Columbianetin acetate (S)-Columbianetin acetate	Structural Classification other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Fungal
(S)-Columbianetin acetate is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N13284

13-Hydroxy-9-octadecenoic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
13-Hydroxy-9-octadecenoic acid is a hydroxy unsaturated fatty acid (HUFA) that has anti-fungal activity .

HY-19584

Variotin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .

HY-N0334

(+)-Magnoflorine Magnoflorine; α-Magnoflorine; Thalictrine	Alkaloids Classification of Application Fields Source classification Ranunculaceae Coptis chinensis Franch. Phenols Polyphenols Metabolic Disease Plants Isoquinoline Alkaloids Disease Research Fields	Fungal
(+)-Magnoflorine (Magnoflorine), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm . (+)-Magnoflorine has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-138145

8-Acetyl-7-hydroxycoumarin	Structural Classification Source classification Coumarins Tagetes lucida Cav. Phenylpropanoids Plants Compositae	Fungal Bacterial
8-Acetyl-7-hydroxycoumarin is a coumarin-like compound found in Mexican patchouli (Tagetes lucida) that has anti-bacterial and anti-fungal activities .

HY-N2014

Verbenalin 1 Publications Verification	Infection Structural Classification Iridoids Classification of Application Fields Terpenoids Verbenaceae Source classification Verbena officinalis Linn. Plants Inflammation/Immunology Disease Research Fields	SARS-CoV
Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury .

HY-N0334A

(+)-Magnoflorine iodide Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide	Alkaloids Classification of Application Fields Source classification Magnoliaceae Phenols Polyphenols Metabolic Disease Magnolia Liliflora Desr. Plants Isoquinoline Alkaloids Disease Research Fields	Fungal
(+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm . (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-N8105

Protoneogracillin	Infection Structural Classification Dioscorea collettii Hook. f. Classification of Application Fields Source classification Plants Disease Research Fields Steroids Dioscoreaceae	Fungal
Protoneogracillin, a furostanol glycoside, shows anti-fungal activity against the plant pathogenic fungus P.oryzae (MMDC=94.0 μM) and cytotoxic activity on K562 cancer cells (IC₅₀=6.6 μM) .

HY-129055

Isoeleutherin	Quinones Iridaceae Classification of Application Fields Source classification Eleutherine plicata Herb. Plants Naphthalene Quinones Disease Research Fields Inflammation/Immunology	Fungal
Isoeleutherin is a naphthopyran derivative isolated from E. americana Merr. Et Heyne with anti-fungal, anti-viral, and anti-tumor activities. Isoeleutherin plays an important role in selective modulation of T helper cell-mediated immune responses .

HY-N0889

Ginkgetin 4 Publications Verification	Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba Disease Research Fields Cancer	COX Wnt Apoptosis Autophagy
Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

HY-N0363R

(+)-Columbianetin (Standard)	Structural Classification Source classification Coumarins Phenylpropanoids Umbelliferae Plants Seriphidium transiliense	Fungal
(+)-Columbianetin (Standard) is the analytical standard of (+)-Columbianetin. This product is intended for research and analytical applications. (+)-Columbianetin is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N0535R

(+)-Magnoflorine chloride (Standard)	Alkaloids Piperidine Alkaloids Structural Classification other families Aristolochia debilis Sieb. et Zucc. Source classification Phenols Polyphenols Plants Aristolochiaceae	Fungal
(+)-Magnoflorine (chloride) (Standard) is the analytical standard of (+)-Magnoflorine (chloride). This product is intended for research and analytical applications. Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm . Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity .

HY-N0363AR

(+)-Columbianetin acetate (Standard)	Structural Classification other families Source classification Coumarins Phenylpropanoids Plants	Fungal
(+)-Columbianetin acetate (Standard) is the analytical standard of (+)-Columbianetin acetate. This product is intended for research and analytical applications. (S)-Columbianetin acetate is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N2014R

Verbenalin (Standard)	Structural Classification Iridoids Terpenoids Verbenaceae Source classification Verbena officinalis Linn. Plants	SARS-CoV
Verbenalin (Standard) is the analytical standard of Verbenalin. This product is intended for research and analytical applications. Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury .

HY-N0393

Glabridin 3 Publications Verification	Structural Classification Classification of Application Fields Source classification Plants Infection Flavonoids Leguminosae Phenols Polyphenols Glycyrrhiza uralensis Fisch. Inflammation/Immunology Disease Research Fields Isoflavones	PPAR Reactive Oxygen Species Bacterial
Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ, with an EC₅₀ of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .

HY-N6635

trans-Nerolidol	Structural Classification Natural Products Source classification Celastraceae Celastrus angulatus Maxim. Plants	Fungal
trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity .

HY-N7030

5,7,3',4'-Tetramethoxyflavone	Infection Structural Classification Flavonoids Classification of Application Fields Flavones Source classification Rutaceae Plants Disease Research Fields Murraya exotica L. Mant.	Fungal Parasite Bacterial
5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling .

HY-13557

Ascomycin 5+ Cited Publications Immunomycin; FR-900520; FK520	Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Antifungal Macrolide Antibiotics Neurological Disease Classification of Application Fields Antibiotics Source classification Disease Research Inflammation/Immunology Disease Research Fields	FKBP Parasite Fungal Antibiotic
Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N6869

Dehydroabietic acid	Infection Structural Classification Microorganisms other families Classification of Application Fields Anti-aging Terpenoids Source classification Diterpenoids Plants Inflammation/Immunology Disease Research Fields	Antibiotic PPAR Bacterial Fungal
Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .

HY-N0126R

Xanthone (Standard) 1 Publications Verification	Infection Structural Classification Classification of Application Fields Source classification Guttiferae Phenols Garcinia mangostana Linn. Plants Inflammation/Immunology Disease Research Fields	Bacterial Influenza Virus Fungal Apoptosis
Xanthone (Standard) is the analytical standard of Xanthone. This product is intended for research and analytical applications. Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities .

HY-N0889R

Ginkgetin (Standard)	Structural Classification Flavonoids Ginkgoaceae Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba	COX Wnt Apoptosis Autophagy
Ginkgetin (Standard) is the analytical standard of Ginkgetin. This product is intended for research and analytical applications. Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

HY-N0393R

Glabridin (Standard)	Infection Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Plants Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch.	PPAR Reactive Oxygen Species Bacterial
Glabridin (Standard) is the analytical standard of Glabridin. This product is intended for research and analytical applications. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC₅₀ of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .

HY-129555

Surfactin 5 Publications Verification	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Bacterial HSV Antibiotic
Surfactin is a potent cyclic lipopeptide biosurfactants consists of four isomers (Surfactin A, B, C and D), which mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects . Surfactin also has antiviral activity against a variety of enveloped viruses .

HY-108485

Damnacanthal	Structural Classification Classification of Application Fields Source classification Plants Infection Quinones Monophenols Anthraquinones Morinda citrifolia Linn. Rubiaceae Phenols Inflammation/Immunology Disease Research Fields	Src Apoptosis Fungal
Damnacanthal is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56 ^lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 ^lck autophosphorylation and phosphorylation of exogenous substrates with IC₅₀s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity against *Candida albicans* .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N6635R

trans-Nerolidol (Standard)	Structural Classification Natural Products Source classification Celastraceae Celastrus angulatus Maxim. Plants	Fungal
trans-Nerolidol (Standard) is the analytical standard of trans-Nerolidol. This product is intended for research and analytical applications. trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity .

HY-N6869R

Dehydroabietic acid (Standard)	Structural Classification Microorganisms other families Terpenoids Source classification Diterpenoids Plants	Antibiotic PPAR Bacterial Fungal
Dehydroabietic acid (Standard) is the analytical standard of Dehydroabietic acid. This product is intended for research and analytical applications. Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .

HY-N7135

Tropolone	Olax imbricata Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Olacaceae Source classification Other Diseases Plants Disease Research Fields	Tyrosinase Fungal
Tropolone is a seven-membered non-benzenoid aromatic compound, which is the precursor of many Azulene derivatives. Tropolone is a potent mushroom tyrosinase inhibitor with an IC₅₀ value of 0.4 μM. Its inhibitory effect can be achieved by dialysis or excess CU ²⁺ Reversa. Tropolone exhibits broad anti-viral and anti-fungal activity and is synergistic upon co-treatment with nucleos(t)ide analog drugs. Tropolone is a promising candidate for research in osteosarcoma .

HY-10863

Anandamide 1 Publications Verification AEA	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Cannabinoid Receptor PPAR TRP Channel GPR55 Fungal Tau Protein Endogenous Metabolite
Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential *anti-fungal* and *anti-inflammatory* activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis .

HY-B0914A

10-Undecenoic acid zinc salt 1 Publications Verification Zinc undecylenate	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal DNA/RNA Synthesis
10-Undecenoic acid zinc salt is a RNA-dependent RNA polymerase (RdRp) inhibitor, with an IC₅₀ of 1.13, 21.33 and 1.79 μM for WT-RdRp, D535ARdRp and D692A-RdRp, respectively. 10-Undecenoic acid zinc salt reduces infectious virus yield in Huh7 cells with an EC₅₀ of 7.43 μM. 10-Undecenoic acid zinc salt has anti-infective and anti-fungal activity. 10-Undecenoic acid zinc salt can be used for the research of Zika virus (ZIKV) .

HY-N0957

(±)-Pinoresinol	Structural Classification Source classification Melia azedarach L. Phenols Polyphenols Plants Meliaceae	Fungal
(±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity .

HY-N2071

Cedrol 1 Publications Verification (+)-Cedrol; α-Cedrol	Structural Classification Cedrus deodara (Roxburgh) G. Don Classification of Application Fields Pinaceae Terpenoids Sesquiterpenes Source classification Plants Inflammation/Immunology Disease Research Fields Cancer	Cytochrome P450 Fungal
Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with K_i of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes . Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, insecticidal, and anti-fungal activities .

HY-B0914AR

10-Undecenoic acid zinc salt (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal DNA/RNA Synthesis
10-Undecenoic acid (zinc salt) (Standard) is the analytical standard of 10-Undecenoic acid (zinc salt). This product is intended for research and analytical applications. 10-Undecenoic acid zinc salt is a RNA-dependent RNA polymerase (RdRp) inhibitor, with an IC₅₀ of 1.13, 21.33 and 1.79 μM for WT-RdRp, D535ARdRp and D692A-RdRp, respectively. 10-Undecenoic acid zinc salt reduces infectious virus yield in Huh7 cells with an EC₅₀ of 7.43 μM. 10-Undecenoic acid zinc salt has anti-infective and anti-fungal activity. 10-Undecenoic acid zinc salt can be used for the research of Zika virus (ZIKV) .

HY-N12621

Antifungal agent 91	Structural Classification Flavanonols Flavonoids Artocarpus elasticus Reinw. ex Blume Source classification Plants Moraceae	Phosphatase
Antifungal agent 91(compound 1) is a dihydroflavonol that can be isolated from the leaves of Artocarpus elasticus. Antifungal agent 91 is a PTP1B inhibitor with an IC₅₀ value of 0.17 μM. Antifungal agent 91 has antifungal activity .

HY-137794

Tetramethylkaempferol	Structural Classification Flavonoids Flavones Source classification Kaempferia parviflora Wall. ex Baker Plants Zingiberaceae	Fungal
Tetramethylkaempferol is an antifungal agent. Tetramethylkaempferol shows antifungal activity against Candida albicansCandida albicans with an IC₅₀ value of 17.63 µg/mL .

HY-N10288

Eucalyptacid A	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Endogenous Metabolite
Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM .

HY-N2502

Tetradehydropodophyllotoxin Dehydropodophyllotoxin	Infection Structural Classification Natural Products Monophenols Classification of Application Fields Source classification Phenols Dysosma versipellis (Hance) M. Cheng ex Ying Plants Berberidaceae Disease Research Fields	Fungal
Tetradehydropodophyllotoxin possesses antifungal activity .

HY-W010201

Citronellol 2 Publications Verification (±)-Citronellol; (±)-β-Citronellol	Structural Classification Other Monoterpenes Microorganisms Classification of Application Fields Terpenoids Source classification Plants Geraniaceae Disease Research Fields Cancer	Reactive Oxygen Species ERK PI3K TNF Receptor Atg8/LC3 p62 Apoptosis Necroptosis Autophagy Fungal
Citronellol ((±)-Citronellol) is an orally active inducer of apoptosis. Citronellol can prevent oxidative stress, mitochondrial dysfunction, and apoptosis in the SH-SY5Y cell Parkinson's disease model induced by 6-OHDA by regulating the ROS-NO, MAPK/ERK, and PI3K/Akt signaling pathways. Citronellol can induce necroptosis in human lung cancer cells through the TNF-α pathway and accumulation of ROS. Citronellol can reduce the levels of LC-3 and p62 to regulate the autophagy pathway, inhibit oxidative stress and neuroinflammation, and thus have neuroprotective effects on Parkinson's rats. Citronellol exhibits anti-fungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis .

HY-N2071R

Cedrol (Standard)	Structural Classification Cedrus deodara (Roxburgh) G. Don Pinaceae Terpenoids Sesquiterpenes Source classification Plants	Cytochrome P450 Fungal
Cedrol (Standard) is the analytical standard of Cedrol. This product is intended for research and analytical applications. Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes . Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, insecticidal, and anti-fungal activities .

HY-118118

Phlebiakauranol aldehyde	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Others
Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .

HY-N9378

3-Oxobetulin	Infection Structural Classification other families Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Plants Disease Research Fields Other Antibiotics	Fungal
3-Oxobetulin, an *antifungal* agent, shows antifungal activities against white rot fungus L. betulina and the brown rot fungus L. sulphureus .

HY-120753

Rimocidin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Fields	Fungal
Rimocidin, a polyene macrolide, is an *antifungal* compound. Rimocidin shows broad‐spectrum antifungal activity against multiple plant‐pathogenic fungi .

HY-19965

UK-2A antibiotic UK 2A	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Fungal
UK-2A (Antibiotic UK 2A) is a potent antifungal antibiotic. UK-2A shows antifungal activity .

HY-N1448

Vincetoxicoside B	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Erythrina stricta Roxb. Plants Compositae Disease Research Fields	Fungal
Vincetoxicoside B shows antifungal activity .

Cat. No.	Product Name	Chemical Structure

HY-17373S

Posaconazole-d5
Posaconazole-d₅ is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity[1].

HY-17373S1

Posaconazole-d4
Posaconazole-d₄ is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity[1].

HY-76200S

Voriconazole-d3
Voriconazole-d₃ is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].

HY-N0415S

Trigonelline-d3 chloride
Trigonelline-d₃ (chloride) is the deuterium labeled Trigonelline chloride. Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee. Trigonelline chloride has anti-HSV-1 , antibacterial, and antifungal activities.

HY-14273S

Isavuconazole-d4
Isavuconazole-d₄ is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi[1].

HY-10863S

Anandamide-d8

Anandamide-d8 is a deuterated labeled Anandamide . Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis .

HY-10882S

Clotrimazole-d5
Clotrimazole-d₅ is the deuterium labeled Clotrimazole. Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity[1][2].

HY-10882S1

Clotrimazole-d10
Clotrimazole-d₁₀ is deuterated labeled Clotrimazole (HY-10882). Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.

HY-77995S

2-Methoxybenzaldehyde-d3
2-Methoxybenzaldehyde-d₃ is the deuterium labeled 2-Methoxybenzaldehyde[1]. 2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity[2].

HY-B0518AS

Naftifine-d3 hydrochloride
Naftifine-d₃ (hydrochloride) is the deuterium labeled Naftifine hydrochloride. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition[1].

HY-W782079

Geraniol-d6 (Major)
Geraniol-d6 (Major) is the deuterated labeled Geraniol (Major). Geraniol is an olefin terpene with oral activity. Geraniol inhibits cell proliferation and promotes apoptosis. Geraniol has antibacterial, antifungal, antioxidant, anti-inflammatory and antitumor activities. Geraniol can be used to study diabetes .

HY-40354AS

Tofacitinib-d3 citrate
Tofacitinib-d₃ (citrate) is deuterium labeled Tofacitinib (citrate). Tofacitinib citrate is an orally available JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively. Tofacitinib citrate has antibacterial, antifungal and antiviral activities.

HY-N7364S

(E)-β-Farnesene-d6
(E)-β-Farnesene-d₆ is deuterated labeled Nerol (HY-N7063). Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca ²⁺ and ROS. *Antifungal* activity .

HY-N7436S

Methyl propyl disulfide-d3
Methyl propyl disulfide-d₃ is deuterated labeled Nerol (HY-N7063). Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca ²⁺ and ROS. *Antifungal* activity .

HY-N0367S

Trans-Anethole-d3
Trans-Anethole-d₃ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria . α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption .

HY-W015551S

trans-2-Decenal-d2
trans-2-Decenal-d₂ is deuterated labeled Coumarin (HY-N0709). Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity .

HY-N5142S

α-Terpineol-d3
α-Terpineol-d₃ is the deuterium labeled α-Terpineol[1]. α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria[2].α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption[2].

HY-B0450S

Ciclopirox-d11
Ciclopirox-d₁₁ is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

HY-B0450S1

Ciclopirox-d11 sodium
Ciclopirox-d₁₁ (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

HY-17395S

Terbinafine-d3 hydrochloride

Terbinafine-d₃ (hydrochloride) is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-B0101S

Fluconazole-d4
Fluconazole-d₄ is the deuterium labeled Fluconazole. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL[1].

HY-17395AS

Terbinafine-d7
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-15660S

Efinaconazole-d4
Efinaconazole-d₄ is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].

HY-B0101S1

Fluconazole-13C2,15N
Fluconazole-13C2,15N (UK-49858-13C2,15N) is the ¹³C and ¹⁵N labeled isotope of Fluconazole (HY-B0101). Fluconazole (UK-49858) is a triazole *antifungal* agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

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