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CAMP

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (76) Cardiovascular Disease (75) Endocrinology (47) Infection (17) Inflammation/Immunology (93) Metabolic Disease (70) Neurological Disease (125)
Click Chemistry:	Azide (1)
Oligonucleotides:	Antioxidants (1) Pre-designed siRNA Sets (2) Antisense Oligonucleotides (2) Chelating Agents (1) siRNAs (2)

414

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1511

Cyclic AMP 5+ Cited Publications Cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; CAMP	Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .

HY-B1511A

Cyclic AMP sodium 5+ Cited Publications Cyclic adenosine monophosphate sodium; Adenosine cyclic 3', 5'-monophosphate sodium; CAMP sodium; Cyclic AMP sodium	Biochemical Assay Reagents	Neurological Disease Metabolic Disease Cancer
Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .

HY-B1511R

Cyclic AMP (Standard) Cyclic adenosine monophosphate (Standard); Adenosine cyclic 3', 5'-monophosphate (Standard); CAMP (Standard)	Endogenous Metabolite	Cancer
Cyclic AMP (Standard) is the analytical standard of Cyclic AMP. Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .

HY-131768

2'-O-Succinyl-cAMP	Cholinesterase (ChE)	Others
2'-O-Succinyl-cAMP is a cAMP analog that can be covalently coupled to acetylcholinesterase. 2'-O-Succinyl-cAMP conjugate has been used as tracers in a classical heterogeneous competitive enzyme immunoassay allowing the determination of cAMP .

HY-123396

8-Chloro-cAMP	PKA	Cancer
8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity .

HY-RS01870

CAMP Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CAMP Human Pre-designed siRNA Set A contains three designed siRNAs for CAMP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CAMP Human Pre-designed siRNA Set A CAMP Human Pre-designed siRNA Set A

HY-RS16241

Camp Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Camp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Camp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Camp Mouse Pre-designed siRNA Set A Camp Mouse Pre-designed siRNA Set A

HY-B1511S

Cyclic AMP-13C5 Cyclic adenosine monophosphate-¹³C₅; Adenosine cyclic 3', 5'-monophosphate-¹³C₅; CAMP-¹³C₅	Isotope-Labeled Compounds	Others
Cyclic AMP- ¹³C₅ is a deuterated cyclic AMP.

HY-134254

8-AHA-cAMP 8-(6-Aminohexylamino)-CAMP	Others	Others
8-AHA-cAMP (8-(6-Aminohexylamino)-cAMP) is a cAMP derivative that modulates the function of proteins by interacting with their cAMP binding domain (CNBD). 8-AHA-cAMP can be used to reveal the mechanism of action of cAMP in cell signaling .

HY-123396A

*8-Chloro-cAMP* sodium**	PKA	Cancer
8-Chloro-cAMP sodium is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP sodium has anticancer activity .

HY-137628

Sp-8-PIP cAMP	PKA	Cancer
Sp-8-PIP cAMP sodium is a non-corresponding isomer of 8-Piperidino-cAMP. 8-Piperidino-cAMP binds with high affinity to site A of the regulatory subunit of cAMP-dependent protein kinase type I (AI). Sp-8-PIP cAMP sodium can be used as an antagonist of cAMP-induced activation .

HY-134299

*8-CPT-cAMP-AM* 8-(4-Chlorophenylthio)-CAMP-AM	Others	Others
8-CPT-cAMP-AM is a highly membrane-permeant analogue of signal molecule cAMP. 8-CPT-cAMP-AM is an activator of cAMP- and cGMP-dependent protein kinases and of Epac (exchange protein activated by cAMP) .

HY-137530

8-MA-cAMP 8-Methylamino-CAMP	PKA	Others
8-MA-cAMP (8-Methylamino-cAMP) is a cyclic AMP analog that acts as a site-selective PKA agonist with similar affinity for the B site of type I and type II protein kinase A. 8-MA-cAMP is used in conjunction with priming analogs that show site A preference, such as 8-piperidinyl cAMP, to achieve selective stimulation of type I .

HY-137381

6-Bnz-cAMP N6-Benzoyl-CAMP	Potassium Channel	Others
6-Bnz-cAMP (N6-Benzoyl-cAMP), a derivative of cyclic adenosine monophosphate (cAMP), is a potent inhibitor of the bTREK-1 potassium channel. 6-Bnz-cAMP can strongly inhibit the bTREK-1 potassium channel through a protein kinase A (PKA) independent mechanism. 6-Bnz-cAMP can be used to explore potential signal transduction proteins in the cAMP signaling pathway .

HY-134340

8-pMeOPT-2'-O-Me-cAMP 8-(4-Methoxyphenylthio)-2'-O-Me-CAMP	Others	Others
8-pMeOPT-2'-O-Me-cAMP is an analogue of the signal molecule cAMP and a potent stimulator of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP does .

HY-131777

2-Cl-cAMP	Others	Others
2-Cl-cAMP is an analog of cAMP and a potent stimulator of cAMP-dependent protein kinases such as PKA type I and II. 2-Cl-cAMP can be used as starting material for cyclic nucleotides .

HY-134321

8-Azido-cAMP	Fluorescent Dye	Others
8-Azido-cAMP is a fluorescent cAMP analog, acting as the model target of detecting cAMP . 8-Azido-cAMP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-134325

8-OH-cAMP 8-Hydroxy-CAMP	PKA	Cardiovascular Disease Metabolic Disease
8-OH-cAMP (8-Hydroxy-cAMP) is a polar, membrane-impermeable cyclic adenosine monophosphate analog that is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. As a polar PKA agonist, 8-OH-cAMP is used to study the role of cAMP in the development and progression of cardiovascular and metabolic diseases .

HY-134302

8-HA-cAMP 8-Hexylamino-CAMP	PKA	Others
8-HA-cAMP is a membrane-permeable cAMP analogue and an activator of cAMP-dependent protein kinase and PKA I. 8-HA-cAMP exerts metabolic stability towards mammalian cyclic nucleotide-responsive phosphodiesterases .

HY-134308

*8-NBD-cAMP* sodium**	Fluorescent Dye	Others
8-NBD-cAMP sodium is a fluorescently labeled cyclic adenosine phosphate (cAMP) analogue. 8-NBD-cAMP sodium retains a similar biological activity to cAMP, regulating their activity by binding to specific proteins such as EPACs or PKA. 8-NBD-cAMP sodium can be used in fluorescent competitive binding experiments to evaluate the binding affinity of newly synthesized EPAC1 agonists to EPAC1 proteins .

HY-131772

2-AHA-cAMP	Others	Others
2-AHA-cAMP is an analogue of natural signal molecule cAMP and an activator of cAMP-dependent protein kinase. 2-AHA-cAMP has a free terminal primary amino group, which can be used for coupling to gels or fluorescent dyes .

HY-134348

8-pHPT-2'-O-Me-cAMP 8-(4-Hydroxyphenylthio)-2'-O-Me-CAMP	Ras	Cardiovascular Disease
8-pHPT-2'-O-Me-cAMP is a cAMP analog and an Epac agonist. 8-pHPT-2'-O-Me-cAMP can be used in cardiac research .

HY-134283

8-Benzylthio-cAMP	PKA Apoptosis	Others
8-Benzylthio-cAMP is a derivative of cyclic adenosine monophosphate (cAMP). 8-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinases. Compared with cyclic adenosine monophosphate, it is more stable to phosphodiesterase (PDE) hydrolysis and has higher membrane permeability. 8-Bn-cAMP can be used to study the role of cAMP in regulating cell proliferation, differentiation and apoptosis .

HY-134298

8-CPT-6-Phe-cAMP 8-(4-Chlorophenylthio)-N6-phenyl-CAMP	PKA	Others
8-CPT-6-Phe-cAMP is an analogue of signal molecule cAMP and a potent protein kinase A (PKA) activator .

HY-134264

8-Br-2'-O-Me-cAMP	Others	Cardiovascular Disease Neurological Disease
8-Br-2'-O-Me-cAMP is an analogue of the signal molecule cyclic AMP (cAMP). 8-Br-2'-O-Me-cAMP is an agonist of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP do. 8-Br-2'-O-Me-cAMP can be used in cardiovascular disease research .

HY-134263

*8-Br-cAMP-AM*	PKA Ras	Cardiovascular Disease
8-Br-cAMP-AM is a cyclic adenosine monophosphate (cAMP) analog that activates two major signal transduction pathways in the heart by mimicking the effects of cAMP: protein kinase A (PKA) and guanosine nucleotide exchange factor (Epac), which is directly activated by cAMP. 8-Br-cAMP-AM can be used to study cardiac ischemia and reperfusion injury .

HY-B0764

Bucladesine sodium 25+ Cited Publications Dibutyryl CAMP sodium salt; DBCAMP sodium salt	PKA Phosphodiesterase (PDE)	Inflammation/Immunology
Bucladesine sodium salt (Dibutyryl-cAMP sodium salt) is a stabilized cyclic AMP (cAMP) analog and a selective PKA activator. Bucladesine sodium salt raises the intracellular levels of cAMP. Bucladesine sodium salt is also a phosphodiesterase (PDE) inhibitor. Bucladesine sodium salt has anti-inflammatory activity and can be used for impaired wound healing .

HY-131842

6-Bn-cAMP N6-Benzyladenosine-3',5'-cyclic monophosphate	PKA	Cancer
6-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinase (PKA) which does not activate Epac. 6-Bn-cAMP increases hydrolytic stability against PDE, esterases, amidases and considerably higher membrane permeability compared to cAMP .

HY-131766

2'-O-Me-cAMP 2'-O-Methyladenosine-3',5'-cyclic monophosphate	Others	Others
2'-O-Me-cAMP is an analogue of natural signal molecule cAMP and a selective stimulator of the exchange factors activated by cAMP (Epac) with low membrane permeability .

HY-134395

6-MB-cAMP N6-Monobutyryl-CAMP	Biochemical Assay Reagents	Others
6-MB-cAMP is a cAMP agonist. 6-MB-cAMP is a membrane permeable analog of cAMP .

HY-B0764B

Bucladesine Dibutyryl CAMP; DBCAMP	PKA	Neurological Disease
Bucladesine (DBcAMP) is a membrane permeable selective activator that activates cyclic adenosine phosphate dependent protein kinase A (PKA). The main regulatory mechanism of Bucladesine involves the cAMP/PKA signaling pathway. When Bucladesine activates PKA, it can promote a variety of cellular processes, including neurodevelopment, growth and plasticity. In particular, the cAMP/PKA signaling pathway plays a key role in the expression of long-term enhancement (LTP) and long-term inhibition (LTD), as well as in the formation of long-term memory in the hippocampus. Bucladesine can be used to study memory formation and neuroplasticity .

HY-103322

*6-Bnz-cAMP* sodium salt**	PKA	Cancer
6-Bnz-cAMP sodium salt is a cell-permeable cAMP analog. 6-Bnz-cAMP selectively activates cAMP-dependent PKA but not Epac signaling pathways .

HY-12306

*8-Bromo-cAMP* sodium salt** 15+ Cited Publications 8-Br-CAMP sodium salt	PKA Apoptosis	Cancer
8-Bromo-cAMP sodium (8-Br-Camp) sodium salt, a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Bromo-cAMP sodium salt has anti-proliferative and apoptotic effects against cancer cells .

HY-12306A

8-Bromo-cAMP 15+ Cited Publications 8-Br-CAMP	PKA Apoptosis	Cancer
8-Bromo-cAMP (8-Br-Camp), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Bromo-cAMP has anti-proliferative and apoptotic effects against cancer cells .

HY-107543

*8-CPT-2Me-cAMP* sodium**	Ras	Others
8-CPT-2Me-cAMP sodium is a selective activator of *exchange proteins activated by cAMP* (Epac)*, the cAMP* sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium activates Epac1 (EC₅₀ = 2.2 μM), but not PKA (EC₅₀> 10 μM) . 8-CPT-2Me-cAMP sodium stimulates Epac-mediated Ca ²⁺ release in pancreatic β-cells in vitro .

HY-B0764A

Bucladesine calcium 25+ Cited Publications Dibutyryl CAMP calcium salt; DBCAMP calcium salt	PKA Phosphodiesterase (PDE) Apoptosis	Others
Bucladesine calcium salt (Dibutyryl-cAMP calcium salt;DC2797 calcium salt) is a cell-permeable cyclic AMP (cAMP) analog and selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP. Bucladesine calcium salt acts as a phosphodiesterase (PDE) inhibitor.

HY-131421

8-PIP-cAMP 8-Piperidino-cyclic AMP	PKA	Cancer
8-PIP-cAMP is a selective cAMP-dependent protein kinase activator and can be used for study of cancer .

HY-116312

8-CPT-2'-O-Me-cAMP	Ras	Cardiovascular Disease
8-CPT-2'-O-Me-cAMP is a Rap1 activator. 8-CPT-2'-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration .

HY-107544

*8-pCPT-2'-O-Me-cAMP-AM*	PKA	Metabolic Disease
8-pCPT-2'-O-Me-cAMP-AM is a cyclic AMP analogue, selectively activates Epac-Rap signaling pathway. 8-pCPT-2'-O-Me-cAMP-AM protects renal function by activating Epac from ischemia injury. 8-pCPT-2'-O-Me-cAMP-AM also stimulates insulin secretion by interaction with PKA pathway .

HY-134389

6-Phe-cAMP N6-Phenyladenosine-3',5'-cyclic monophosphate	PKA	Cancer
6-Phe-cAMP is a site-selective and highly membrane-permeant activator of protein kinase A (PKA), with a strong preference for site A of both isozymes. 6-Phe-cAMP can undergo phosphorothioate modification .

HY-120994

Rp-8-CPT-cAMPS sodium	PKA	Neurological Disease Inflammation/Immunology
Rp-8-CPT-cAMPS sodium, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependent PKA I and II. Rp-8-CPT-cAMPS sodium preferentially selects site A of RI compares to site A of RII and site B of RII compares to site B of RI .

HY-120994A

Rp-8-CPT-cAMPS	PKA	Neurological Disease Inflammation/Immunology
Rp-8-CPT-cAMPS, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependent PKA I and II. Rp-8-CPT-cAMPS preferentially selects site A of RI compares to site A of RII and site B of RII compares to site B of RI .

HY-131763

*2'-O-MB-cAMP* sodium** 2'-O-Monobutyryl cyclic AMP sodium	Others	Others
2'-O-MB-cAMP (2'-O-Monobutyryl cyclic AM) sodium is an activatable proagent of Cyclic AMP (HY-B1511) .

HY-100530A

Rp-cAMPS	PKA	Neurological Disease
Rp-cAMPS, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (K_is of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS is resistant to hydrolysis by phosphodiesterases .

HY-100530D

Rp-cAMPS sodium salt 3 Publications Verification	PKA	Neurological Disease
Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (K_is of 12.5 µM and 4.5 µM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis by phosphodiesterases .

HY-100530

Rp-cAMPS triethylammonium salt	PKA	Neurological Disease
Rp-cAMPS triethylammonium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (K_is of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS triethylammonium salt is resistant to hydrolysis by phosphodiesterases .

HY-P3770

Phosphate acceptor peptide	PKC	Others
Phosphate acceptor peptide is a substrate for cAMP-dependent protein kinase (PKA). phosphate acceptor peptide is also a weak PKC inhibitor .

HY-P3786

H-Arg-Gly-Tyr-Ala-Leu-Gly-OH	PKA PKC	Cancer
H-Arg-Gly-Tyr-Ala-Leu-Gly-OH is a competitive and CAMP dependent protein kinase inhibitor .

HY-111673

8-CPT-Cyclic AMP sodium 8-CPT-CAMP sodium; 8-(p-Chlorophenylthio)-CAMP sodium	PKA Phosphodiesterase (PDE)	Inflammation/Immunology
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). 8-CPT-Cyclic AMP sodium is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC₅₀ of 0.9 μM. 8-CPT-Cyclic AMP sodium also inhibits PDE III and PDE IV with IC₅₀Epac and is a potent Epac activator .

HY-D1187

2-Aza-ε-cAMP	Fluorescent Dye	Others
2-Aza-ε-cAMP is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1511

Cyclic AMP 5+ Cited Publications Cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; CAMP	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .

HY-124151

Adenosine-2'-monophosphate 2'-AMP; Adenosine 2'-phosphate; AMP 2'-phosphate	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Adenosine Receptor Endogenous Metabolite
Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2’,3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2’,3’-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A_2A receptor activation .

HY-N2168

Pinoresinol 4-O-β-D-glucopyranoside (+)-Pinoresinol 4-O-β-D-glucopyranoside	Cardiovascular Disease Monophenols other families Classification of Application Fields Source classification Lignans Phenols Phenylpropanoids Plants Disease Research Fields	Others
Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is the major active furofuran type lignans in Fructus Forsythiae. Pinoresinol 4-O-β-D-glucopyranoside shows antioxidant, blood pressure reducing, and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory effects .

HY-15371

Forskolin Maximum Cited Publications 116 Publications Verification Coleonol; Colforsin; HL 362	Structural Classification Classification of Application Fields Terpenoids Labiatae Source classification Metabolic Disease Diterpenoids Plants Inflammation/Immunology Disease Research Fields Endocrinology Pueraria montana (Lour.) Merr.	Organoid Adenylate Cyclase FXR Autophagy PKC
Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC₅₀ of 41 nM and an EC₅₀ of 0.5 μM for type I adenylyl cyclase . Forskolin is also an inducer of intracellular *cAMP* formation . Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR . Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy .

HY-N1189

DL-Syringaresinol diacetate Syringaresinol Diacetate	Structural Classification Natural Products Source classification Plants Menispermaceae	Others
DL-Syringaresinol diacetate is a glucoside. DL-Syringaresinol inhibits cAMP phosphodiesterase and alleviation of stress .

HY-N3550

Catalponol	Other Terpenoids Structural Classification Catalpa ovata G. Don Classification of Application Fields Terpenoids Source classification Bignoniaceae Plants Disease Research Fields Cancer	Others
Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells .

HY-N2658

5,7-Diacetoxy-8-methoxyflavone	Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Phosphodiesterase (PDE)
5,7-Diacetoxy-8-methoxyflavone is a natural product that could come from scutellaria genus plants. 5,7-Diacetoxy-8-methoxyflavone has inhibitory activity for cAMP phosphodiesterase .

HY-N2168R

Pinoresinol 4-O-β-D-glucopyranoside (Standard)	Structural Classification Monophenols other families Source classification Lignans Phenols Phenylpropanoids Plants	Others
Pinoresinol 4-O-β-D-glucopyranoside (Standard) is the analytical standard of Pinoresinol 4-O-β-D-glucopyranoside. This product is intended for research and analytical applications. Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is the major active furofuran type lignans in Fructus Forsythiae. Pinoresinol 4-O-β-D-glucopyranoside shows antioxidant, blood pressure reducing, and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory effects .

HY-15371R

Forskolin (Standard)	Structural Classification Terpenoids Labiatae Source classification Diterpenoids Plants Pueraria montana (Lour.) Merr.	Organoid Adenylate Cyclase FXR Autophagy PKC
Forskolin (Standard) is the analytical standard of Forskolin. This product is intended for research and analytical applications. Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC₅₀ of 41 nM and an EC₅₀ of 0.5 μM for type I adenylyl cyclase . Forskolin is also an inducer of intracellular cAMP formation . Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR . Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy .

HY-126754

Archangelicin	Structural Classification Source classification Pseudodictamnus aucheri (Boiss.) Salmaki & Siadati Coumarins Phenylpropanoids Umbelliferae Plants	Nuclear Factor of activated T Cells (NFAT) Phosphodiesterase (PDE)
Archangelicin is an inhibitor for cAMP-phosphodiesterase (cAMP-PDE) with IC₅₀ >400 μM. Archangelicin inhibits nuclear factor of activated T cell (NFAT) with IC₅₀ of 9 μM. Archangelicin exhibits antitumor and anti-inflammatory .

HY-N0113

Hordenine 1 Publications Verification Ordenina; Peyocactine	Cardiovascular Disease Alkaloids Structural Classification Monophenols other families Classification of Application Fields Other Alkaloids Source classification Phenols Plants Disease Research Fields	Bacterial Antibiotic
Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-N0113B

Hordenine hydrochloride 1 Publications Verification Ordenina hydrochloride; Peyocactine hydrochloride	Coryphantha vivipara var arizonica Structural Classification Alkaloids Monophenols Cactaceae Other Alkaloids Source classification Phenols Plants	Antibiotic
Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-N13132

Hellicoside	Plantaginaceae Structural Classification Source classification Phenols Polyphenols Plantago asiatica L. Plants	Phosphodiesterase (PDE) Lipoxygenase
Hellicoside is a natural product that can be obtained from plantain. Hellicoside has inhibitory activity against cAMP phosphodiesterase and 5-lipoxygenase .

HY-N3324

Mangostanol (+)-Mangostanol	Structural Classification Flavonoids Source classification Guttiferae Plants Garcinia hanburyi Hook. f. Other Flavonoids	Phosphodiesterase (PDE)
Mangostanol ((+)-Mangostanol) is a polyoxygenated xanthone mangostanol, which can be isolated from the shell of Garcinia mangostana, and has inhibitory effect on cAMP phosphodiesterase (PDE) .

HY-124371

Amentoflavone hexaacetate	Structural Classification Flavonoids Viburnaceae Source classification Plants Biflavones Viburnum lantana L.	Others
Amentoflavone hexaacetate is a 3,5-cyclic nucleotide phosphodiesterase inhibitor with antiplatelet aggregation activity. Amentoflavone hexaacetate can inhibit the aggregation of eluted human platelets induced by ADP or collagen. Amentoflavone hexaacetate can also inhibit the cAMP phosphodiesterase activity in human platelets. Amentoflavone hexaacetate can significantly increase the cAMP level of platelets in the presence of prostaglandin E1. Amentoflavone hexaacetate has anti-angiogenic and anti-metastatic effects .

HY-111896

7-Methoxyrosmanol 7-O-Methoxyrosmanol	Structural Classification other families Classification of Application Fields Terpenoids Source classification Other Diseases Phenols Polyphenols Diterpenoids Plants Disease Research Fields	PEPCK
7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters .

HY-N0113R

Hordenine (Standard) Ordenina (Standard); Peyocactine (Standard)	Cardiovascular Disease Structural Classification Alkaloids other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields	Bacterial Antibiotic
Hordenine (Standard) is the analytical standard of Hordenine. This product is intended for research and analytical applications. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-N8092

Kushenol B	Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology	Phosphodiesterase (PDE)
Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities . Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC₅₀ of 31 µM .

HY-B1505

Acefylline 1 Publications Verification Theophyllineacetic acid; Theophylline-7-acetic acid	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	HDAC Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE)
Acefylline, a xanthine derivative, is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .

HY-N3464

Isopedicin	Structural Classification Flavonoids Flavonones Source classification Plants Annonaceae Fissistigma oldhamii (Hemsl.) Merr.	Phosphodiesterase (PDE)
Isopedicin potently and concentration-dependently inhibits superoxide anion (O2 U?) production in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated cells. Isopedicin increases cAMP formation and PKA activity in FMLP-activated cells by inhibiting phosphodiesterase (PDE) activity .

HY-126383

Spilanthol	Structural Classification Natural Products Source classification Plants Compositae Medicago truncatula Gaertn.	Bacterial
Spilanthol is an orally active analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial and insecticidal compound.pilanthol can induce *cAMP* to inhibit negative regulation of urinary concentration mechanism. Spilanthol can be use as diuretic research .

HY-W012980

Isovaleric acid	Structural Classification Classification of Application Fields Source classification Endocrine diseases Metabolic Disease Endogenous metabolite Biological Pesticide Research Agricultural Research Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Disease Research Fields	Endogenous Metabolite AMPK PKA
Isovaleric acid is an oral active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the *cAMP/PKA* pathway. Isovaleric acid can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders .

HY-N6901

Luteolin 7-sulfate	Structural Classification Flavonoids other families Classification of Application Fields Flavones Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	Epigenetic Reader Domain
Luteolin 7-sulfate is isolated from Phyllospadix iwatensis Makino, a marine plant. Luteolin 7-sulfate attenuates TYR gene expression through the intervention of a cAMP-responsive element binding protein (CREB)- and microphthalmia-associated transcription factor (MITF)-mediated signaling pathway, leading to the decreased melanin synthesis .

HY-B1505R

Acefylline (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	HDAC Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE)
Acefylline (Standard) is the analytical standard of Acefylline. This product is intended for research and analytical applications. Acefylline, a xanthine derivative, is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .

HY-W012980R

Isovaleric acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite	Endogenous Metabolite AMPK PKA
Isovaleric acid (Standard) is the analytical standard of Isovaleric acid. This product is intended for research and analytical applications. Isovaleric acid is an oral active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. Isovaleric acid can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders .

HY-N6256

Ilexsaponin B2	Cardiovascular Disease Aquifoliaceae Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Ilex pubescens Hook. et Arn. Plants Disease Research Fields	Phosphodiesterase (PDE)
Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC₅₀ values of 48.8 μM and 477.5 μM, respectively .

HY-P2878

Phosphodiesterase I PDE	Classification of Application Fields Disease Research Fields Cancer	Phosphodiesterase (PDE)
Phosphodiesterase (PDE) is an enzyme that can catalyze the hydrolysis of the 3' ring phosphate bond of cyclic nucleotides, and is often used in biochemical research. Phosphodiesterase acts as an important regulator of signal transduction mediated by the second messenger molecules cAMP and cGMP. According to their specificity to cyclic nucleotides, they can also be divided into different types, such as PDE1-PDE11, which also have certain potential in various diseases .

HY-16558

Butein 4 Publications Verification 2’,3,4,4’-tetrahydroxy Chalcone	Structural Classification Chalcones Flavonoids other families Classification of Application Fields Anti-aging Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	EGFR Autophagy Apoptosis Phosphodiesterase (PDE)
Butein is a cAMP-specific PDE inhibitor with an IC₅₀ of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC₅₀s of 16 and 65 μM for EGFR and p60 ^c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).

HY-N3773

Dodoviscin A	Structural Classification Flavonoids Flavones Source classification Dodonaea viscosa (L.) Jacq. Sapindaceae Plants	Tyrosinase
Dodoviscin A is a pigmentation-altering agent, which can be isolated from the aerial parts of Dodonaea viscosa. Dodoviscin A inhibits melanin production in B16-F10 melanoma cells. Dodoviscin A suppresses mushroom tyrosinase activity, and tyrosinase activity induced by 3-isobutyl-1-methylxanthine. Dodoviscin A also inhibits the phorphosylation of cAMP response element binding protein, induced by 3-isobutyl-1-methylxanthine and forskolin .

HY-N0113A

Hordenine sulfate Ordenina sulfate; Peyocactine sulfate	Structural Classification Monophenols Gramineae Source classification Hordeum vulgare Phenols Plants	Antibiotic
Hordenine sulfate (Ordenina sulfate) is an active compound extracted from malted barley that has melanin-inhibiting activity. Hordenine sulfate significantly reduced melanin content and reduced intracellular cAMP levels. Hordenine sulfate inhibits the expression of proteins related to melanogenesis, including microblind transcription factor (MITF), tyrosinase, tyrosinase-related protein (TRP)-1, and TRP-2. Therefore, Hordenine sulfate can be used as an active ingredient to inhibit pigmentation .

HY-N2118

Bilobetin 1 Publications Verification	Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Plants Biflavones Ginkgo biloba Disease Research Fields	PPAR PKA Akt p38 MAPK ERK
Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity .

HY-N1860

3-O-Methylquercetin	Rhamnus nakaharai (Hayata) Hayata Structural Classification Flavonoids Classification of Application Fields Flavones Plants Rhamnaceae Inflammation/Immunology Disease Research Fields	Phosphodiesterase (PDE)
3-O-Methylquercetin (3-MQ) is a major component from the plant Rhamnus nakaharai and has antiviral activity and potential antiasthmatic efficacy. 3-O-Methylquercetin inhibits total cAMP and cGMP-phosphodiesterase (PDE). The IC₅₀ values of 3-O-Methylquercetin (3-MQ) against PDE1-PDE5 are in the range of 1.6-86.9 μM. 3-O-Methylquercetin is a non-competitive inhibitor of PDE2 and a competitive inhibitor of PDE4 .

HY-16558R

Butein (Standard)	Structural Classification Chalcones Flavonoids other families Source classification Phenols Polyphenols Plants	EGFR Autophagy Apoptosis Phosphodiesterase (PDE)
Butein (Standard) is the analytical standard of Butein. This product is intended for research and analytical applications. Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).

HY-N6727

Gliotoxin Aspergillin	Structural Classification Anti-inflammation/Immunoregulatory Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Biological Pesticide Research Agricultural Research Infection Microorganisms Antibiotics Inflammation/Immunology Disease Research Fields	Apoptosis PKA NF-κB Bacterial Fungal Antibiotic
Gliotoxin is a secondary metabolite, the most abundant mycotoxin secreted by A. fumigatus, inhibits the phagocytosis of macrophages and the immune functions of other immune cells . Gliotoxin inhibits inducible NF-κB activity by preventing IκB degradation, which consequently induces host-cell apoptosis . Gliotoxin activates PKA and increases intracellular cAMP concentration; modulates actin cytoskeleton rearrangement to facilitate A. fumigatus internalization into lung epithelial cells . Gliotoxin is a potent NOTCH2 transactivation inhibitor, can effectively induce apoptosis of chronic lymphocytic leukemia (CLL) cells .

HY-N2118R

Bilobetin (Standard)	Structural Classification Flavonoids Ginkgoaceae Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba	PPAR PKA Akt p38 MAPK ERK
Bilobetin (Standard) is the analytical standard of Bilobetin. This product is intended for research and analytical applications. Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity .

HY-124717

YC-001	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
YC-001 is an inverse agonist and antagonist of rod opsin. YC-001 reversibly binds rod opsin and stabilizes the rod opsin structure. YC-001 protects mice from bright light-induced retinal degeneration. YC-001 has the potential for the research of retinal degeneration .

HY-N2038

3,5,6,7,8,3',4'-Heptemthoxyflavone	Structural Classification Flavonols Flavonoids Rutaceae Plants Citrus reticulata Blanco	Phosphodiesterase (PDE)
3,5,6,7,8,3',4'-Heptemthoxyflavone, a flavonoid from satsuma peel, is an orally available CREB activator with anti-tumor and anti-neuroinflammatory activity. 3,5,6,7,8,3',4'-Heptemthoxyflavone inhibits collagenase activity and increases the content of type I procollagen in human dermal fibroblast neoblast (HDFn) cells. 3,5,6,7,8,3',4'-Heptemthoxyflavone induces brain-derived neurotrophic factor (BDNF) expression through the cAMP/ERK/CREB signaling pathway and reduces phosphodiesterase activity in C6 glioma .

HY-N3945

Glaucine O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396	Infection Alkaloids Structural Classification other families Classification of Application Fields Source classification Plants Isoquinoline Alkaloids Glaucium flavum Inflammation/Immunology Disease Research Fields Papaveraceae	Phosphodiesterase (PDE) Calcium Channel MMP NF-κB
Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 (PDE4), with a K_i of 3.4 µM in human bronchial tissues and polymorphonuclear leukocytes. Glaucine induces relaxation of human isolated bronchi by antagonizing calcium channels. Additionally, Glaucine inhibits the activation of NF-κB, leading to a reduction in the expression of the MMP-9 gene, thereby suppressing the migration and invasion of breast cancer cells. Therefore, Glaucine holds potential for research in asthma and breast cancer .

HY-N3945R

Glaucine (Standard)	Alkaloids Structural Classification other families Source classification Plants Isoquinoline Alkaloids Glaucium flavum Papaveraceae	Phosphodiesterase (PDE) Calcium Channel Adrenergic Receptor Dopamine Receptor Influenza Virus
Glaucine (Standard) is the analytical standard of Glaucine. This product is intended for research and analytical applications. Glaucine (O,O-Dimethylisoboldine) is an alkaloid isolated from Glaucium flavum with antitussive, bronchodilation and anti-inflammatory properties. Glaucine is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor with Kis of 3.4 μM in human bronchus and polymorphonuclear leukocytes. Glaucine is also a non-selective α-adrenoceptor antagonist, a Ca2+ entry blocker, and a weak dopamine D1 and D2 receptor antagonist. Glaucine has antioxidative and antiviral activities .

HY-113513

5-HEPE	Microorganisms Source classification	Others
5(S)-HEPE is an active metabolite of eicosapentaenoic acid. It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of G protein-coupled receptor 119 (GPR119). It increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration of 10 μM. 5(S)-HEPE increases glucose-induced insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells when used at a concentration of 10 μM. Serum levels of 5(S)-HEPE are elevated in patients with hyperlipidemia.

HY-N0092R

Inosine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Adenosine Receptor Endogenous Metabolite
Inosine (Standard) is the analytical standard of Inosine. This product is intended for research and analytical applications. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors . In Vitro:Inosine dose-dependently stimulates cAMP production mediated through the A_2AR . Inosine dose-dependently induces hA_2AR-mediated ERK1/2 phosphorylation . Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes . In Vivo:Inosine (10-100 mg/kg; i.p.) exhibits antinociceptive effect in mice .

HY-B1009

Ethylenediaminetetraacetic acid trisodium salt 5+ Cited Publications EDTA trisodium salt; Trisodium EDTA	Classification of Application Fields Disease Research Fields Cancer	Ferroptosis Bacterial SOD
Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .

HY-Y0682

Ethylenediaminetetraacetic acid 5+ Cited Publications EDTA	Classification of Application Fields Disease Research Fields Cancer	Biochemical Assay Reagents Bacterial SOD
Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .

HY-N2038R

3,5,6,7,8,3',4'-Heptemthoxyflavone (Standard)	Structural Classification Flavonols Flavonoids Rutaceae Plants Citrus reticulata Blanco	Phosphodiesterase (PDE)
3,?5,?6,?7,?8,?3',?4'-Heptemthoxyflavone (Standard) is the analytical standard of 3,?5,?6,?7,?8,?3',?4'-Heptemthoxyflavone. This product is intended for research and analytical applications. 3,5,6,7,8,3',4'-Heptemthoxyflavone, a flavonoid from satsuma peel, is an orally available CREB activator with anti-tumor and anti-neuroinflammatory activity. 3,5,6,7,8,3',4'-Heptemthoxyflavone inhibits collagenase activity and increases the content of type I procollagen in human dermal fibroblast neoblast (HDFn) cells. 3,5,6,7,8,3',4'-Heptemthoxyflavone induces brain-derived neurotrophic factor (BDNF) expression through the cAMP/ERK/CREB signaling pathway and reduces phosphodiesterase activity in C6 glioma .

Cat. No.	Product Name	Chemical Structure

HY-N0113S

Hordenine-d6
Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-135119

Salmeterol-d3
Salmeterol-d₃ is a deuterium labeled Salmeterol. Salmeterol is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1].

HY-B1511S

Cyclic AMP-13C5
Cyclic AMP- ¹³C₅ is a deuterated cyclic AMP.

HY-14773S

(Rac)-Mirabegron-d5
(Rac)-Mirabegron-d₅ is a deuterium labeled (Rac)-Mirabegron. (Rac)-Mirabegron is the racemate of Mirabegron. Mirabegron is a selective β3-adrenoceptor agonist[1].

HY-14302S1

Salmeterol-d5
Salmeterol-d5 is a deuterated labeled Salmeterol . Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC₅₀s of 9.6, 6.1, and 5.9, respectively .

HY-17453S

Salmeterol-d3 xinafoate
Salmeterol-d₃ (xinafoate) is the deuterium labeled Salmeterol xinafoate. Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1].

HY-17453S1

Salmeterol-13C6 xinafoate
Salmeterol- ¹³C₆ (xinafoate) is the ¹³C₆ labeled Salmeterol (xinafoate). Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.

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