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Results for "

Lymphocyte

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CTLA-4 (5) LAG-3 (3) Adenosine Receptor (2) Akt (2) Antibiotic (8) Apoptosis (34) Arenavirus (4) Aryl Hydrocarbon Receptor (1) Autophagy (8) Bacterial (15) Bcl-2 Family (1) Biochemical Assay Reagents (4) Calcium Channel (2) CD20 (4) CD28 (1) CD3 (1) CXCR (1) Cyclophilin (1) Deubiquitinase (1) DGK (1) Dihydroorotate Dehydrogenase (2) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (4) DOCK (2) Drug Metabolite (4) EBV (2) EGFR (1) Endogenous Metabolite (13) Epigenetic Reader Domain (1) ERK (1) Ferroptosis (2) FKBP (5) Fluorescent Dye (3) Fungal (6) Glutathione S-transferase (2) HBV (2) Histamine Receptor (1) Histone Methyltransferase (3) HIV (12) HIV Protease (1) HPV (3) HSV (3) IFNAR (1) Influenza Virus (2) Integrin (10) Interleukin Related (8) IRAK (1) Isotope-Labeled Compounds (4) Itk (1) JAK (5) Leukotriene Receptor (1) LPL Receptor (25) Microtubule/Tubulin (1) Monoamine Oxidase (1) Na+/H+ Exchanger (NHE) (1) Na+/K+ ATPase (1) Necroptosis (1) NF-κB (3) NOD-like Receptor (NLR) (1) Nucleoside Antimetabolite/Analog (7) Orthopoxvirus (6) p38 MAPK (3) Parasite (3) PD-1/PD-L1 (5) PDI (1) Phosphatase (6) Phosphodiesterase (PDE) (2) PI3K (1) PIN1 (1) PKC (6) Polo-like Kinase (PLK) (1) Potassium Channel (3) PPAR (1) Prostaglandin Receptor (4) PROTACs (1) Proton Pump (2) Pyroptosis (1) Radionuclide-Drug Conjugates (RDCs) (1) ROR (4) RSV (1) SHP2 (1) Sodium Channel (1) Src (5) STAT (3) STING (1) Tim3 (1) TNF Receptor (2) Toll-like Receptor (TLR) (1) Topoisomerase (8) TRP Channel (1) Tyrosinase (1) VEGFR (1)
By Research Areas:	Cancer (111) Cardiovascular Disease (4) Endocrinology (3) Infection (43) Inflammation/Immunology (130) Metabolic Disease (10) Neurological Disease (10)
Oligonucleotides:	Aptamers (2) Adjuvant (1)

228

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

170

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Triptonine B	HIV	Infection
Triptonine B, a sesquiterpene pyridine alkaloid, inhibits HIV replication in H9 lymphocytes with an EC₅₀ value of <0.10 μg/mL .

CellTracker CM-DiI CM-DiI	Fluorescent Dye	Others
CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome that can be used for tracking the migration of lymphocytes. CellTracker CM-DiI is feasible to detect labeled cells in histological sections (excitation 553 nm; emission 570 nm) .

Saucerneol (-)-Saucerneol	Others	Inflammation/Immunology
Saucerneol is a lignans that can be isolated from Saururus chinensis. Saucerneol inhibits LPS-induced or Con A-induced lymphocytes proliferation. Saucerneol inhibits mixed lymphocyte response. Saucerneol also inhibits mitogens-induced cytokines secretion .

Brazilein	Apoptosis	Inflammation/Immunology
Brazilein is an important immunosuppressive component isolated from Caesalpinia sappan L. Brazilein induces apoptosis in mice spleen lymphocytes .

Mycestericin C	Others	Cancer
Mycestericin C is a compound isolated from the culture broth of Mycelia sterilia ATCC 20349. Mycestericin C suppresses the proliferation of lymphocytes in the mouse allogeneic mixed lymphocyte reaction .

BMS 488043 BMS 043	HIV	Infection Inflammation/Immunology
BMS 488043 (BMS 043) is an orally active and well-tolerated inhibitor of the attachment of human immunodeficiency virus type 1 (HIV-1) to CD4+ lymphocytes .

Neotripterifordin	HIV	Infection
Neotripterifordin is a inhibitor of HIV. Neotripterifordin has anti-HIV replication activity in H9 lymphocyte cells with an EC₅₀ of 25 nM .

Cerebroside D	Endogenous Metabolite	Inflammation/Immunology
Cerebroside D, a glycoceramide compound, improves experimental colitis in mice with multiple targets against activated T lymphocytes .

BI-1950	Integrin	Inflammation/Immunology
BI-1950 is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor. LFA-1 is an essential component in normal immune system function and a target for agent discovery .

Suberosol	HIV	Infection
Suberosol, a C31 lanostane-type triterpene, is an anti-HIV drug. Suberosol shows anti-HIV replication activity in H9 lymphocyte cells with an EC₅₀ of 3 μg/mL .

NU/ICRF 500	Topoisomerase	Inflammation/Immunology
NU/ICRF 500 is a topo II catalytic inhibitor which increases CREST negative micronuclei in human lymphocytes .

W140 hydrobromide	LPL Receptor	Inflammation/Immunology
W140 hydrobromide is a S1P1 antagonist with the K_i of 2.84 μM, and can enhanceof capillary leakage and restoration of lymphocyte egress .

TC-SP 14	LPL Receptor	Inflammation/Immunology
TC-SP 14 (compound 14) is an orally active and potent S1P1 agonist (EC₅₀ = 0.042 μM) with minimal activity at S1P3 (EC₅₀ = 3.47 μM). TC-SP 14 significantly reduces blood lymphocyte counts and attenuates a delayed type hypersensitivity (DTH) response to antigen challenge .

5-Carboxyfluorescein diacetate N-succinimidyl ester 5+ Cited Publications	Fluorescent Dye	Others
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye (Ex=492 nm, Em=517 nm). 5-Carboxyfluorescein diacetate N-succinimidyl ester can label cells by covalently binding to intracellular molecules. 5-Carboxyfluorescein diacetate N-succinimidyl ester is used to track lymphocyte migration and proliferation .

Tyrosinase (206-214), human	Tyrosinase	Inflammation/Immunology Cancer
Tyrosinase (206-214), human (AFLPWHRLF), a 9-amino acid peptide, is a tyrosinase epitope. Tyrosinase (206-214), human can be recognized by HLA-A24 restricted, tumor-infiltrating lymphocytes (TIL) .

Bimolane AT-1727	Topoisomerase	Cancer
Bimolane (AT-1727), a human topoisomerase II inhibitor, can be used as an anti-neoplastic agent and for the research of psoriasis. Bimolane shows leukemogenic activity and induces multiple types of chromosomal aberrations in human lymphocytes .

Panobacumab KBPA101	Bacterial	Infection
Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of *P. aeruginosa* .

BIRT 377 2 Publications Verification	Integrin Interleukin Related	Inflammation/Immunology
BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1), with a K_i of 25.8 nM. BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders .

SWS1	PD-1/PD-L1 Monoamine Oxidase	Cancer
SWS1 is a d-(+)-biotin-conjugated PD-L1 inhibitor (IC₅₀: 1.8 nM) with anticancer activity. SWS1 can increase the number of tumor-infiltrating lymphocytes and exhibit anti-tumor efficacy in the B16-F10 mouse model (TGI=66.1%) .

CAY10410 11-Oxo-prosta-5Z,12E,14Z-trien-1-oic acid	PPAR	Cancer
CAY10410 (11-Oxo-prosta-5Z), a 15d-PGJ2 analog, is a potent PPARγ agonist. CAY10410 has the ability to activate PPARγ in human B cells without killing B lymphocytes .

L-Leucyl-L-Leucine methyl ester hydrochloride 5+ Cited Publications LLOMe hydrochloride; Leu-Leu methyl ester hydrochloride; H-Leu-Leu-OMe hydrochloride	Endogenous Metabolite	Inflammation/Immunology
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrochloride, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress .

L-Leucyl-L-Leucine methyl ester hydrobromide 5+ Cited Publications LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide	Endogenous Metabolite	Inflammation/Immunology
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress .

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

Sivifene A-007	Others	Inflammation/Immunology Cancer
Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors .

MRE3008F20	Adenosine Receptor	Inflammation/Immunology
MRE3008F20 is a highly efficient, highly selective and radioactive adenosine A₃ receptor (AA₃R) antagonist (K_i=1.8 nM). MRE3008F20 effectively antagonises Cl-IB-MECA-induced cAMP production in resting lymphocytes with an IC₅₀ value of 5 nM. MRE3008F20 can be used in the study of AA3R .

Phyllodulcin	Phosphodiesterase (PDE)	Metabolic Disease Inflammation/Immunology
Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling .

RS-25344 hydrochloride	Phosphodiesterase (PDE)	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
RS-25344 hydrochloride is a selective cAMP-phosphodiesterase 4 (PDE 4; PDE IV) inhibitor with an IC₅₀ of 0.28 nM in human lymphocytes. RS-25344 hydrochloride has only weak inhibitory effects on PDE I, II, III (IC₅₀ of >100 μM, 160 μM, 330 μM, respectively). RS-25344 hydrochloride has anti-inflammatory, memory- and cognition enhancing, and antineoplastic effects .

Ezatiostat hydrochloride TER199; TLK199 hydrochloride	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment .

LF 1695	Interleukin Related	Others
LF 1695 is an immunomodulator. LF 1695 enhances the proliferative response of T cells by increasing the production of IL2 (interleukin-2) or the expression of the IL2 receptor. LF 1695 also increases CONA-induced inhibitory activity in human lymphocytes. LF 1695 can be used to study the proliferative and inhibitory activity of T cell subpopulations, as well as their role in immune regulation .

Ezatiostat 5+ Cited Publications TER199(free base); TLK199	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment .

TASP0277308	LPL Receptor	Inflammation/Immunology
TASP0277308 is a highly selective S1P₁ antagonist. TASP0277308 possesses immunomodulatory activities, including lymphopenia, a block in T cell egress from the thymus, marginal zone B cell displacement, and the upregulation of CD69 expression on lymphocytes. TASP0277308 can be used for the research of collagen-induced arthritis in mice .

RORγt agonist 3	ROR	Inflammation/Immunology
RORγt agonist 3 is a potent agonist of RORγt. RORγt agonist 3 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 3 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136326A1, compound 23) .

RORγt agonist 2	ROR	Inflammation/Immunology
RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17) .

LX2931	LPL Receptor	Others Inflammation/Immunology
LX2931 is an inhibitor of Sphingosine 1-Phosphate Lyase (S1PL). LX2931 works by increasing levels of S1P inside and outside the cell. The decrease in S1PL activity leads to a significant increase in S1P content in tissues, especially in lymphoid tissues which may lead to a restricted exodus of lymphocytes from secondary immune tissues, resulting in lymphocytopenic and immunosuppressive effects in the peripheral circulation. LX2931 can be used in research for the treatment of autoimmune diseases, especially rheumatoid arthritis .

CXCR2 antagonist 3	CXCR	Inflammation/Immunology Cancer
CXCR2 antagonist 3 (compound 11h) is a potent antagonist of CXC chemokine receptor 2 (CXCR2). CXCR2 antagonist 3 demonstrates double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch. CXCR2 antagonist 3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3 ⁺ T lymphocytes into the Pan02 tumor tissues .

XP-524	Epigenetic Reader Domain	Cancer
XP-524 is a potent BET and EP300 inhibitor. XP-524 shows great tumoricidal activity in vivo. XP-524 prevents KRAS-induced, neoplastic transformation in vivo and extends survival in two transgenic mouse models of aggressive PDAC. XP-524 also enhances the presentation of self-peptide and tumor recruitment of cytotoxic T lymphocytes. XP-524 has the potential for the research of pancreatic ductal adenocarcinoma (PDAC) .

S1P1 agonist 5	LPL Receptor	Inflammation/Immunology
S1P1 agonist 5 is a selective and orally active S1P1 agonist. S1P1 agonist 5 inhibits the lymphocyte egress from the lymphoid tissue to the peripheral blood. S1P1 agonist 5 has the potential for the research of multiple sclerosis (MS) .

Lapachol 2 Publications Verification	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite	Infection Inflammation/Immunology Cancer
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

UK-78282 hydrochloride	Potassium Channel	Inflammation/Immunology
UK-78282, a novel piperidine, potent and selective Kv1.3 blocker with an IC₅₀ of 200 nM. UK-78,282 effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil .

Alemtuzumab Campath-IH	Apoptosis	Cancer
Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research .

Firategrast 5+ Cited Publications SB 683699	Integrin	Neurological Disease
Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist. Firategrast reduces trafficking of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity .

Quin C1	Others	Inflammation/Immunology
Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury .

G6PDi-1 2 Publications Verification	PDI	Metabolic Disease Inflammation/Immunology
G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC₅₀ of 0.07 μM for human G6PD. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells .

Lapachol (Standard)	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite	Infection Inflammation/Immunology Cancer
Lapachol (Standard) is the analytical standard of Lapachol. This product is intended for research and analytical applications. Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

Tubulin polymerization/V-ATPase-IN-1	Microtubule/Tubulin Proton Pump Apoptosis	Inflammation/Immunology Cancer
Tubulin polymerization/V-ATPase-IN-1 (compound F10) is a Tubulin polymerization/V-ATPase inhibitor. Tubulin polymerization/V-ATPase-IN-1 shows robust antiproliferation activity against four human cancer cell lines, and exerts antiproliferative activity by inhibiting tubulin and V-ATPase. Tubulin polymerization/V-ATPase-IN-1 induces immunogenic cell death in addition to apoptosis, and inhibits tumor growth in an RM-1 homograft model with enhanced T lymphocyte infiltration .

Cat. No.	Product Name

HY-L172

Immunopotentiator Compound Library

86 compounds

Immunity refers to the ability of the body to resist the invasion of pathogenic microorganisms and resist a variety of diseases. Immunocompromised will inevitably lead to a series of diseases. Immunopotentiator are a class of compounds that enhance immune function and induce immune response. Immunopotentiator can activate the proliferation and differentiation of one or more kinds of immune active cells in the body, promote the secretion of lymphocytes, and then enhance the immune function of the body. Immunopotentiator are mainly used in the treatment of tumors, infectious diseases and immunodeficiency diseases. In addition, immunopotentiator are often used as adjuvants in combination with vaccine antigens to enhance the immunogenicity of vaccines.

MCE designs a unique collection of 86 compounds with definite or potential Immunopotentiating effect, mainly targeting the NOD-like Receptor (NLR), Toll-like Receptor (TLR), NF-κB, etc. It is an effective tool for development and research of anti-cancer, anti-infectious diseases and anti-immunodeficiency diseases compounds.

HY-L031

Small Molecule Immuno-Oncology Compound Library

494 compounds

Immuno-Oncology is a type of immunotherapy that has the specific purpose of treating cancer. It works by stimulating our immune system to fight back. Normally, our immune system is able to destroy cancer cells in our body, however sometimes cancer cells can adapt and mutate, effectively hiding from our immune system. This is when tumors can develop and become a threat to our health. Immuno-oncology involves mobilizing lymphocytes to recognize and eliminate cancer cells using the body’s immune system. There are several immuno-oncology treatments available, including Immune cell therapy (CAR-T), monoclonal antibodies (mABs) and checkpoint inhibitors, cytokines and cancer vaccines.

MCE Small Molecule Immuno-Oncology Compound Library offers 494 bioactive tumor immunology compounds that target some important checkpoints such as PD1/PD-L1, CXCR, Sting, IDO, TLR, etc. This library is a useful tool for Immuno-oncology research.

Cat. No.	Product Name	Type

HY-D1627

CellTracker CM-DiI CM-DiI	Fluorescent Dyes/Probes
CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome that can be used for tracking the migration of lymphocytes. CellTracker CM-DiI is feasible to detect labeled cells in histological sections (excitation 553 nm; emission 570 nm) .

HY-D0056

5-Carboxyfluorescein diacetate N-succinimidyl ester 5+ Cited Publications	Fluorescent Dyes/Probes
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye (Ex=492 nm, Em=517 nm). 5-Carboxyfluorescein diacetate N-succinimidyl ester can label cells by covalently binding to intracellular molecules. 5-Carboxyfluorescein diacetate N-succinimidyl ester is used to track lymphocyte migration and proliferation .

HY-153209G

ISATM51 (GMP)	Fluorescent Dye
ISATM51 (GMP) is a GMP grade ISATM51. ISATM51 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses .

Cat. No.	Product Name	Type

HY-P0001

Thymus factor X TFX-Jelfa	Native Proteins
Thymic factor X (TFX-Jelfa) is an aqueous extract from juvenile calf thymuses and a natural stimulator of lymphocyte function .

HY-D1005A22

Poloxamer 338 (F108) PEG-PPG-PEG, 14600 (Averag)	Co-solvents
Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats .

HY-NP086

Jacalin	Native Proteins
Jacalin is a lectin, that can be extracted from jackfruit seeds. Jacalin interacts with human immunoglobulins and lymphocytes, and can be used in immunology research .

HY-153209G

ISATM51 (GMP)	Biochemical Assay Reagents
ISATM51 (GMP) is a GMP grade ISATM51. ISATM51 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses .

HY-D1005A14

Poloxamer 217 (F77) PEG-PPG-PEG, 6600 (Averag)	Co-solvents
Poloxamer 217 F77 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 6600. Poloxamer 217 F77 inhibits proliferation of human lymphocyte cell IIBR1 .

Cat. No.	Product Name	Target	Research Area

HY-P3813

Tyrosinase (206-214), human	Tyrosinase	Inflammation/Immunology Cancer
Tyrosinase (206-214), human (AFLPWHRLF), a 9-amino acid peptide, is a tyrosinase epitope. Tyrosinase (206-214), human can be recognized by HLA-A24 restricted, tumor-infiltrating lymphocytes (TIL) .

HY-P3333

KSPWFTTL	Peptides	Inflammation/Immunology Cancer
KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes .

HY-P3333A

KSPWFTTL TFA	Peptides	Inflammation/Immunology Cancer
KSPWFTTL TFA is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL TFA can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes .

HY-P2665

Lymphocyte activating pentapeptide	Peptides	Others
Lymphocyte activating pentapeptide is a short peptide sequence found in the Fc region of human IgG1 that has the ability to activate lymphocytes. Lymphocyte activating pentapeptide can be used to study the activation mechanisms of B cells and T cells, and their role in immune responses .

HY-106171

NBI-6024	Peptides	Metabolic Disease
NBI-6024, an altered peptide ligand (APL), is an epitope recognized by inflammatory interferon-gamma-producing T helper lymphocytes in type 1 diabetic patients .

HY-106187

MART-1 (27-35) (human)	Peptides	Inflammation/Immunology
MART-1 (27-35) (human) is an immunogenic epitope recognized by HLA-A2-restricted melanoma-specific tumor-infiltrating lymphocytes (TIL) .

HY-P5742

ELAAWCRWGFLLALLPPGIAG	Peptides	Cancer
ELAAWCRWGFLLALLPPGIAG (P5) is derived from rat HER2/neu protein with 21 amino acid length (aa 5-25). ELAAWCRWGFLLALLPPGIAG can induce cytotoxic T lymphocyte (CTL) responses in mice bearing HER2-positive tumours .

HY-P5742A

ELAAWCRWGFLLALLPPGIAG TFA	Peptides	Cancer
ELAAWCRWGFLLALLPPGIAG TFA (P5) is derived from rat HER2/neu protein with 21 amino acid length (aa 5-25). ELAAWCRWGFLLALLPPGIAG TFA can induce cytotoxic T lymphocyte (CTL) responses in mice bearing HER2-positive tumours .

HY-113963

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

HY-106374

Elpamotide	Peptides	Cancer
Elpamotide is an epitope peptide derived from VEGFR2. Elpamotide induces cytotoxic T lymphocytes (CTLs) to kill VEGFR2-expressing endothelial cells. Elpamotide has potential immunostimulatory and antineoplastic activities. Elpamotide can be used in the research of cancer, such as pancreatic cancer .

HY-13634

Ezatiostat hydrochloride TER199; TLK199 hydrochloride	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment .

HY-13634A

Ezatiostat Maximum Cited Publications 7 Publications Verification TER199(free base); TLK199	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

HY-P5581

Alloferon 1	Peptides	Infection Inflammation/Immunology Cancer
Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera) .

HY-P3736

Myelopeptide-2 MP-2	Interleukin Related	Cancer
Myelopeptide-2 is a peptide originally isolated from the supernatant of porcine bone marrow cell cultures, can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. Myelopeptide-2 also recover depressed interleukin-2 (IL-2) synthesis and interleukin-2 receptor (IL-2R) expression. Myelopeptide-2 involves in immunity homeostasis, is perspective to be applied in antitumor and antivirus research .

HY-P5058

Cyclolinopeptide B	Peptides	Inflammation/Immunology
Cyclolinopeptide B is a cyclic nonapeptide with immunosuppressive activity on human peripheral blood lymphocytes .

HY-P1870

OVA sequence (323-336)	Peptides	Inflammation/Immunology
OVA sequence (323-336) is a cognate helper T-lymphocyte peptide that is employed to enhance CTL epitope immunogenicity.

HY-P4720

Interleukin-6 fragment (human)	Peptides	Inflammation/Immunology Cancer
Interleukin-6 fragment (human) is a pleiotropic cytokine produced by lymphocytes and non-lymphocytes. The Interleukin-6 fragment (human) coding gene is located on human chromosome 7, with a length of approximately 5 kilobases. Interleukin-6 fragment (human) has potential applications in immune response, acute response, inflammation, tumors, and hematopoiesis .

HY-P2495

OVA (241-270)	Peptides	Cancer
OVA (241-270), a non-specific cytotoxic T lymphocyte (CTL) peptide, is a fragmented peptide of OVA (ovalbumin) antigen .

HY-P2495A

OVA (241-270) (TFA)	Peptides	Inflammation/Immunology
OVA (241-270) TFA, a non-specific cytotoxic T lymphocyte (CTL) peptide, is a fragmented peptide of OVA (ovalbumin) antigen .

HY-105039

Disomotide G209-2M; GP100:209-217(210M); MPS-22	Peptides	Cancer
Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma .

HY-105025A

Thymocartin TFA Thymopoietin II (32-35) (TFA); TP 4 TFA	Apoptosis	Inflammation/Immunology
Thymocartin TFA is the TFA salt form of Thymocartin (HY-105025). Thymocartin TFA inhibits apoptosis of peripheral blood lymphocytes in HIV infected individuals. Thymocartin TFA is potential for immunodeficiency diseases research .

HY-P1569

LCMV gp33-41 2 Publications Verification	Arenavirus	Inflammation/Immunology
LCMV gp33-41, the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .

HY-P10264

MAGE-3 peptide MAGE-3(168-176), human	Peptides	Cancer
MAGE-3 peptide (MAGE-3 168-176, human) is a peptide encoded by human MAGE-3 gene, which is expressed in tumor cells, presented by HLA and recognized by cytolytic T lymphocytes (CTL) as tumor antigen .

HY-P1569A

LCMV gp33-41 TFA 2 Publications Verification	Arenavirus	Inflammation/Immunology
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .

HY-P3410

Trichomide A	SHP2 Phosphatase	Inflammation/Immunology
Trichomide A is a potent activator of SHP2. Trichomide A is a natural cyclodepsipeptide. Trichomide A displays immunosuppressive activity against activated T lymphocyte–mediated immune responses in Con A-activated T cells. Trichomide A have the potential for the research of immune-related skin diseases .

HY-P1835

CEF8, Influenza Virus NP (383-391)	Influenza Virus	Inflammation/Immunology
CEF8, Influenza Virus NP (383-391), an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B ^2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated with escape from cytotoxic T lymphocytes*-mediated immunity .

HY-P2521

NS2 (114-121), Influenza	Influenza Virus	Infection Inflammation/Immunology
NS2 (114-121), Influenza, the 114-121 fragment of influenza nonstructural protein 2 (NS2), is a influenza-derived epitope. NS2 (114-121), Influenza can be used for the research of CD8 ⁺ cytotoxic T lymphocyte (CTL) in antiviral immune responses .

HY-148663

Mitogenic Pentapeptide Tripalmitoyl pentapeptide	Peptides	Inflammation/Immunology
Mitogenic Pentapeptide (Tripalmitoyl pentapeptide) is an effective activator of *B lymphocyte* mitogen and polyclonal*. Mitogen Pentapeptide is a synthetic N-terminal analog of E. coli* outer membrane lipoproteins (cysteinyl-seryl-seryl-asparaginyl-alanine). Mitogenic Pentapeptide can be used for the study of immune adjuvants .

HY-P10245

Fusion glycoprotein (92-106)	RSV	Inflammation/Immunology
Fusion glycoprotein 92-106 is a polypeptide from fusion protein of respiratory syncytial virus (RSV). Fusion glycoprotein 92-106 acts as MHC class I-restricted CTL epitope, that all 15 amino acids are required for efficient recognition by cytotoxic T lymphocyte (CTL) .

HY-P1862

HSV-gB2 (498-505)	HSV	Infection
HSV-gB2 (498-505) is an immunodominant epitope from herpes simplex virus (HSV) glycoprotein B residues 498-505, acts as H-2Kb-restricted and HSV-1/2-cross-reactive cytotoxic T-lymphocyte (CTL) recognition epitope .

HY-P1855

HER2/neu (654-662) GP2	EGFR	Cancer
HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers .

HY-P1812

AUNP-12 3 Publications Verification NP-12	PD-1/PD-L1	Cancer
AUNP-12 (NP-12) is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. AUNP-12 exhibits immune activation, excellent antitumor activity, and potential for better management of immune-related adverse events (irAEs) .

HY-P1881

HPV16-E711-20 epitope	HPV	Cancer
HPV16-E711-20 epitope is a well-known HLA-A ^0201-restricted human cytotoxic T lymphocyte* (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. HPV16 CTL epitopes may be good candidates for the development of an effective peptide-based antitumor vaccine .

HY-P10402

BMAP 28 (bovine)	Bacterial	Infection Cancer
BMAP 28, bovine is an antibacterial peptide. BMAP 28, bovine exhibits antimicrobial activity against gram-positive and gram-negative bacteria, by increasing cell membrane permeability, and causing leakage of cell contents. BMAP 28, bovine exhibits cytotoxicity to cancer cells and activated human lymphocytes. BMAP 28, bovine induces apoptosis through depolarization of mitochondrial membrane potential .

HY-P1812A

AUNP-12 TFA 3 Publications Verification NP-12 TFA	PD-1/PD-L1	Cancer
AUNP-12 TFA (NP-12 TFA) is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. AUNP-12 TFA exhibits immune activation, excellent antitumor activity, and potential for better management of immune-related adverse events (irAEs) .

HY-P10593

Influenza A NP (383-391) (HLA-B27)	Peptides	Cancer
Influenza A NP (383-391) (HLA-B27) is a peptide sequence derived from tetanus toxin. Influenza A NP (383-391) (HLA-B27) is a broadly immunogenic CD4+ T helper cell epitope that enhances CD8+ cytotoxic T lymphocyte (CTL) responses. Influenza A NP (383-391) (HLA-B27) can be used in breast cancer research .

HY-P2524

MAGE-3 (271-279)	Peptides	Cancer
MAGE-3 (271-279) is a 271-279 residue peptide derived from melanoma antigens encoded by MAGE-3. MAGE-3 is a cytolytic T lymphocyte (CTL)-defined MAGE-3 protein associated with the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is overexpressed in different human tumor types, including malignant melanoma, but not by normal tissues except for testis and placenta .

HY-P1920

CEF19, Epstein-Barr Virus latent NA-3A (458-466)	EBV	Inflammation/Immunology
CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain). CEF19, Epstein-Barr Virus latent NA-3A (458-466) can significantly affect cytotoxic T-lymphocyte (CTL) recognition .

HY-P10607

IALYLQQNW	EBV	Cancer
IALYLQQNW is a specific nonapeptide sequence derived from the tumor-associated antigen latent membrane protein 1 (LMP1) encoded by Epstein-Barr virus (EBV). As a latent T-cell epitope, IALYLQQNW is able to activate EBV-specific cytotoxic T lymphocytes (CTLs), which are able to recognize and kill EBV-infected cells expressing LMP1. IALYLQQNW plays an important role in the immune response against EBV-associated tumors and can be used in the study of Hodgkin's disease and nasopharyngeal carcinoma .

HY-P10496

MAGE-A1-derived peptide	Peptides	Cancer
MAGE-A1-derived peptide is a short peptide sequence derived from MAGE-A1 protein. As a tumor-specific antigen, MAGE-A1-derived peptide can be recognized and activated by cytotoxic T lymphocytes (CTLs), thereby generating an immune response to tumor cells expressing MAGE-A1. This immune response can lead to the lysis and death of tumor cells. MAGE-A1-derived peptide can be used in the study of tumor immunity .

HY-P3644

EEKLIVVAF	Peptides	Cancer
EEKLIVVAF is a pepitide, can be recognized on HLA-B44 by the anti-melanoma cytolytic T-cell (CTL) clone LB33- CTL-159/5 .

HY-P10424

OPBP-1	PD-1/PD-L1	Cancer
OPBP-1 is a D-peptide obtained by phage display screening, molecular docking and molecular dynamics simulation. OPBP-1 has high stability and strong antitumor and oral activity. OPBP-1 can selectively bind PD-L1 protein, significantly block the interaction between PD-1 and PD-L1, and this blocking effect helps to restore and improve the function of T lymphocytes and reduce the proportion of bone marrow derived suppressor cells (MDSCs) to combat tumor-induced immune escape. OPBP-1 can be used in cancer immunotherapy research .

HY-P3070

H2-D b restricted epitopes VSV Nucleoprotein (52-59)	Peptides	Infection Others
H2-D b restricted epitopes VSV Nucleoprotein (52-59) is a 9-mer peptide derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). H2-D b restricted epitopes VSV Nucleoprotein (52-59) binds to MHC class I molecules and presents itself to CD8+ T cells, thereby activating cytotoxic T lymphocytes (CTLs), which can recognize and kill cells expressing the corresponding antigen. H2-D b restricted epitopes VSV Nucleoprotein (52-59) can be used in the development of CTL vaccines against Ebola virus .

HY-P1571

Nucleoprotein (396-404) NP 396	Arenavirus	Inflammation/Immunology
Nucleoprotein (396-404) is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .

HY-P1571A

Nucleoprotein (396-404) (TFA) NP 396 TFA	Arenavirus	Inflammation/Immunology
Nucleoprotein (396-404) TFA is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) TFA is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .

HY-P0263A

Dermaseptin TFA	Bacterial Fungal	Infection
Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .

Cat. No.	Product Name	Target	Research Area

HY-P99568

Telitacicept RC18	Inhibitory Antibodies	Inflammation/Immunology
Telitacicept (RC18) is a fully human TACI-Fc fusion protein. Telitacicept is a dual B lymphocyte stimulator (BLyS)/APRIL (a proliferation-inducing ligand) inhibitor that effectively blocks proliferation of B lymphocytes. Telitacicept can be used in research of B-cell autoimmune disease .

HY-P99214

Panobacumab KBPA101	Bacterial	Infection
Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of *P. aeruginosa* .

HY-P99429

Alefacept BG 9273; Human LFA 3IgG fusion protein; LFA 3TIP	Inhibitory Antibodies	Others
Alefacept (BG 9273) is a human lymphocyte function-associated antigen 3/immunoglobulin 1 fusion protein. Alefacept can be used for the research of chronic plaque psoriasis .

HY-P9948

Alemtuzumab Campath-IH	Apoptosis	Cancer
Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research .

HY-P9952

Belimumab 2 Publications Verification LymphoStat B	TNF Receptor CD20	Inflammation/Immunology Cancer
Belimumab (LymphoStat B) is a humanized IgG1λ monoclonal antibody against B-lymphocyte stimulator (BLyS) protein. Belimumab antagonizes BLyS activity in autoimmune diseases and B-lymphocyte malignancies. Belimumab can be used for systemic lupus erythematosus (SLE) research .

HY-P99326

Tositumomab Anti-Human CD20 Recombinant Antibody	Radionuclide-Drug Conjugates (RDCs) CD20	Cancer
Tositumomab is a murine IgG2a lambda monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes .

HY-P9918

Tremelimumab Ticilimumab; CP-675206	CTLA-4	Inflammation/Immunology Cancer
Tremelimumab (Ticilimumab) is a fully human monoclonal antibody specific for cytotoxic T-lymphocyte antigen-4 (CTLA-4) and can be used for metastatic melanoma research .

HY-P99607

Clenoliximab IDEC-151	Inhibitory Antibodies	Inflammation/Immunology
Clenoliximab (IDEC-151) is a macaque-human chimeric monoclonal antibody (immunoglobulin G4) specific for the CD4 molecule on the surface of T lymphocytes. Clenoliximab can be used for the research of rheumatoid arthritis .

HY-P990056

Oberotatug	Inhibitory Antibodies	Inflammation/Immunology
Oberotatug is a human IgG1κ antibody targeting the lymphocyte antigen LY75 .

HY-P990054

Eramkafusp Alfa	CD20	Cancer
Eramkafusp Alfa is a human IgG1 antibody targeting the mouse B lymphocyte CD20 antigen MS4A1 .

HY-P990041

Firastotug	CTLA-4	Inflammation/Immunology Cancer
Firastotug is an IgG1κ antibody targeting CTLA4. CTLA4 is a cytotoxic T lymphocyte-associated protein and a key immune checkpoint in the fields of autoimmunity and cancer .

HY-P99484

Botensilimab AGEN 1181	CTLA-4	Cancer
Botensilimab (AGEN 1181), a human anti-*cytotoxic T-lymphocyte* antigen 4 (CTLA-4)** monoclonal antibody, is an innate and adaptive immune activator. Botensilimab can be used for the research of cancer .

HY-P99760

Nurulimab BCD-145	CTLA-4	Cancer
Nurulimab (BCD-145) is an anti-*cytotoxic T lymphocyte* antigen-4 (anti-CTLA-4)** human monoclonal antibody. Nurulimab can be can be used in research of melanoma .

HY-P9961

Ofatumumab	CD20	Cancer
Ofatumumab is a fully human anti-CD20 monoclonal antibody that induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity in CD20-expressing B lymphocytes .

HY-P9901

Ipilimumab 4 Publications Verification MDX-010; BMS-734016	CTLA-4	Cancer
Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 (CTLA-4) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies .

HY-P99961

Tifcemalimab JS004	CD28	Cancer
Tifcemalimab (JS004) is a humanized anti-*BTLA (B and T lymphocyte* attenuation factor)** monoclonal antibody. Tifcemalimab blocks the interaction of HVEM-BTLA by binding to BTLA, and thus blocks the inhibitory signaling pathway mediated by BTLA. Tifcemalimab can be used in research of cancer .

HY-P99446

Atacicept TACI-Ig; TACI-Fc 5	Inhibitory Antibodies	Inflammation/Immunology
Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease .

HY-P9911

Vedolizumab 1 Publications Verification Anti-Human Lymphocyte α4β7 integrin, Humanized Antibody	Integrin	Inflammation/Immunology Cancer
Vedolizumab is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.

HY-P99387

TSR-033	LAG-3	Cancer
TSR-033 is a high affinity human IgG4 antibody targeting LAG-3 (lymphocyte activation gene-3), a co-receptor associated with impaired T cell function and often co-expressed with PD-1, that enhances T cell function and PD-1 blocking activity in vitro and in vivo. TSR-033 has anti-tumor activity .

HY-P99762

Obrindatamab MGD009	CD3	Cancer
Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer .

HY-P99219

Sifalimumab MEDI-545; MDX 1103	IFNAR	Inflammation/Immunology
Sifalimumab (MEDI-545) is an anti-IFNα monoclonal antibody. Sifalimumab suppresses the abnormal immune activity by binding to multiple interferon-alpha (IFNα) subtypes. Sifalimumab can be used in systemic lupus erythematosus (SLE) research .

HY-108831

Natalizumab 2 Publications Verification	Integrin	Inflammation/Immunology Cancer
Natalizumab is a recombinant, humanized IgG4 monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses .

HY-108831A

Natalizumab (Solution) 2 Publications Verification	Integrin	Inflammation/Immunology Cancer
Natalizumab (Solution) is a recombinant, humanized IgG4 monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses .

HY-P99052

Tislelizumab 2 Publications Verification	PD-1/PD-L1	Inflammation/Immunology Cancer
Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma .

HY-P99933

Eftilagimod alfa IMP321; LAG-3Ig	LAG-3	Cancer
Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II. Eftilagimod alfa mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Eftilagimod alfa can be used for metastatic melanoma and metastatic breast carcinoma research .

Species:	Human (79) Marmoset (1) Rhesus Macaque (13) Mouse (47) Rat (10) Bovine (1) Cynomolgus (12) Rabbit (2) Dog (1) Canine (3) Pig (2)
Tag:	His (110) SUMO (3) T7 (1) Tag Free (21) Avi (6) Myc (3) GST (3) Trx (2) Fc (39) Flag (2)
Source:	HEK293 (122) CHO (4) P. pastoris (8) Sf9 insect cells (2) E. coli (34)

Cat. No.	Compare	Product Name	Species	Source

HY-P74441

	Lymphocyte antigen 86/MD-1 Protein, Mouse (HEK293, His) LY86; Lymphocyte antigen 86; MD-1; MMD-1; RP105-associated	Mouse	HEK293
	Lymphocyte antigen 86/MD-1 acts synergistically with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and influence cytokine production.It plays a crucial role in promoting the high expression of CD180 on the cell surface, forming an M-shaped tetramer with two CD180-LY86 heterodimers.Lymphocyte antigen 86/MD-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Lymphocyte antigen 86/MD-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71801

	Lymphocyte antigen 6G/LY6G Protein, Mouse (P.pastoris) Ly6g; Lymphocyte antigen 6G; Ly-6G; Ly-6G.1	Mouse	P. pastoris
	Lymphocyte antigen 6G/LY6G protein is uniquely expressed in bone marrow, indicating its involvement in the hematopoietic microenvironment. This suggests a role in regulating immune cell development or function within the bone marrow niche. Lymphocyte antigen 6G/LY6G Protein, Mouse (P.pastoris) is the recombinant mouse-derived Lymphocyte antigen 6G/LY6G protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Lymphocyte antigen 6G/LY6G Protein, Mouse (P.pastoris) is 93 a.a., with molecular weight (glycosylation form) of ~34 kDa.

HY-P74441A

	Lymphocyte antigen 86/MD-1 Protein, Mouse (HEK293, C-6His) LY86; Lymphocyte* antigen 86; MD-1; MMD-1; RP105-associated	Mouse	HEK293

HY-P70223

	Lymphocyte antigen 86/LY86 Protein, Human (HEK293, Fc) rHuLymphocyte antigen 86/MD-1, Fc; Lymphocyte antigen 86; LY86; MD1; Protein MD-1	Human	HEK293
	Lymphocyte antigen 86/LY86 acts synergistically with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and influence cytokine production. It plays a crucial role in promoting the high expression of CD180 on the cell surface, forming an M-shaped tetramer with two CD180-LY86 heterodimers. Lymphocyte antigen 86/LY86 Protein, Human (HEK293, Fc) is the recombinant human-derived Lymphocyte antigen 86/LY86 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Lymphocyte antigen 86/LY86 Protein, Human (HEK293, Fc) is 142 a.a., with molecular weight of 45-55 kDa.

HY-P75920

	Lymphocyte antigen 6A-2/LY6A Protein, Mouse (His) Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; SCA-1; TAP; Ly6	Mouse	E. coli
	Lymphocyte antigen 6A-2/LY6A Protein, crucial for T-cell activation, plays a key role in immune responses. Its ability to facilitate T-cell activation underscores its importance in regulating T-cell responses and immune surveillance. The molecular interactions and signaling pathways in which LY6A participates during T-cell activation highlight its significance as a key orchestrator in immune responses, contributing to immune homeostasis. Lymphocyte antigen 6A-2/LY6A Protein, Mouse (His) is the recombinant mouse-derived Lymphocyte antigen 6A-2/LY6A protein, expressed by E. coli , with N-His labeled tag. The total length of Lymphocyte antigen 6A-2/LY6A Protein, Mouse (His) is 93 a.a., with molecular weight of ~10.9 kDa.

HY-P71539

	Lymphocyte antigen 6E/LY6E Protein, Human (His-SUMO) LY6E; 9804; RIGE; SCA2; TSA1; Lymphocyte antigen 6E; Ly-6E; Retinoic acid-induced gene E protein; RIG-E; Stem cell antigen 2; SCA-2; Thymic shared antigen 1; TSA-1	Human	E. coli
	Lymphocyte antigen 6E/LY6E protein is a GPI-anchored cell surface regulator that regulates T cell receptor signaling through interaction with CD3Z/CD247. It limits the entry of human coronaviruses, serves as the primary receptor for syncytin-A, and may modulate nicotinic acetylcholine receptor activity. Lymphocyte antigen 6E/LY6E Protein, Human (His-SUMO) is the recombinant human-derived Lymphocyte antigen 6E/LY6E protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P74328

	CD19 Protein, Mouse (HEK293, His) B-Lymphocyte antigen CD19; CD19; B-Lymphocyte surface antigen B4	Mouse	HEK293
	The CD19 protein acts as a coreceptor for B cell antigen receptors, lowering the signaling threshold and initiating B cell responses to antigens. It activates a cascade leading to PI3K activation and Ca(2+) mobilization. CD19 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD19 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD19 Protein, Mouse (HEK293, His) is 271 a.a., with molecular weight of ~51 kDa.

HY-P71796

	Lymphocyte antigen 6C1/LY6C1 Protein, Mouse (P.pastoris, His) Ly6c1; Lymphocyte antigen 6C1; Ly-6C1	Mouse	P. pastoris
	Lymphocyte antigen 6C1 enables acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity.Lymphocyte antigen 6C1 is involved in acetylcholine receptor signaling pathway.Lymphocyte antigen 6C1/LY6C1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Lymphocyte antigen 6C1/LY6C1 protein, expressed by P.pastoris , with N-6*His labeled tag.

HY-P70217

	Lymphocyte antigen 6H/LY6H Protein, Human (HEK293, His) rHuLymphocyte antigen 6H/LY6H, His; Lymphocyte Antigen 6H; Ly-6H; LY6H	Human	HEK293
	LY6H mediates the myelin trophic and neurotrophic effects of PSAP/Prosaposin protein through GPR37 and GPR37L1 receptors. Ligand-mediated internalization of these receptors results in ERK phosphorylation signaling. Lymphocyte antigen 6H/LY6H Protein, Human (HEK293, His) is the recombinant human-derived Lymphocyte antigen 6H/LY6H protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Lymphocyte antigen 6H/LY6H Protein, Human (HEK293, His) is 90 a.a., with molecular weight of ~18.0 kDa.

HY-P71830

	Lymphocyte antigen 6E/LY6E Protein, Mouse (P.pastoris, His, SUMO) Ly6e; Ly67; Sca-2; Tsa-1Lymphocyte antigen 6E; Ly-6E; Stem cell antigen 2; Thymic shared antigen 1; TSA-1	Mouse	P. pastoris
	LY6E is a GPI-anchored cell surface protein that regulates T lymphocyte function by binding to CD3Z/CD247, affecting proliferation, differentiation and activation.It modulates T cell receptor signaling and exhibits antiviral activity against mouse hepatitis virus.Lymphocyte antigen 6E/LY6E Protein, Mouse (P.pastoris, His, SUMO) is the recombinant mouse-derived Lymphocyte antigen 6E/LY6E protein, expressed by P.pastoris , with N-His, N-SUMO labeled tag.

HY-P74330

	CD19 Protein, Human (HEK293, His) B-Lymphocyte antigen CD19; CD19; B-Lymphocyte surface antigen B4	Human	HEK293
	The CD19 protein is a B cell antigen receptor coreceptor that enhances downstream signaling pathways, lowers the activation threshold, and helps B cells respond to antigens. It activates phosphatidylinositol 3-kinase and mobilizes intracellular Ca(2+). CD19 Protein, Human (HEK293, His) is the recombinant human-derived CD19 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD19 Protein, Human (HEK293, His) is 291 a.a., with molecular weight of ~47 kDa.

HY-P77527

	CD19 Protein, Mouse (Biotinylated, HEK293, His) B-Lymphocyte antigen CD19; CD19; B-Lymphocyte surface antigen B4	Mouse	HEK293
	The CD19 protein acts as a coreceptor for B cell antigen receptors, lowering the signaling threshold and initiating B cell responses to antigens. It activates a cascade leading to PI3K activation and Ca(2+) mobilization. CD19 Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived CD19 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD19 Protein, Mouse (Biotinylated, HEK293, His) is 271 a.a., with molecular weight of ~31 KDa.

HY-P701243

	CD19 Protein, Human (FITC, HEK293, His) B-Lymphocyte antigen CD19; CD19; B-Lymphocyte surface antigen B4	Human	HEK293
	CD19 Protein, a B-cell antigen receptor coreceptor, enhances downstream signaling pathways, lowers activation threshold, and aids B-cell responses to antigens. It activates phosphatidylinositol 3-kinase and mobilizes intracellular Ca(2+). CD19 is essential for B-1 cell differentiation and influences B cell proliferation, immunoglobulin levels, and high-affinity antibody production. It complexes with CD21, CD81, and CD225, interacts with CD81 for receptor trafficking, and binds to VAV, GRB2, SOS, PLCG2, LYN, and p85 subunit of phosphatidylinositol 3-kinase when phosphorylated. CD19 Protein, Human (FITC, HEK293, His) is the recombinant human-derived CD19 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD19 Protein, Human (FITC, HEK293, His) is 272 a.a., with molecular weight of 68-72 kDa.

HY-P70001

	CTLA-4 Protein, Human (HEK293, Fc) rHuCytotoxic T-Lymphocyte protein 4/CTLA-4, Fc; Cytotoxic T-Lymphocyte protein 4; Cytotoxic T-Lymphocyte-associated antigen 4; CTLA4; CD152	Human	HEK293
	The CTLA-4 protein is a key inhibitory receptor and a major negative regulator of T cell responses in coordination of immune regulation. Its unique property is its significantly increased affinity for B7 ligands (CD80/CD86) compared with CD28. CTLA-4 Protein, Human (HEK293, Fc) is the recombinant human-derived CTLA-4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CTLA-4 Protein, Human (HEK293, Fc) is 126 a.a., with molecular weight of ~50-58 kDa.

HY-P75439

	CD19 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) B-Lymphocyte antigen CD19; CD19; B-Lymphocyte surface antigen B4	Rhesus Macaque;Cynomolgus	HEK293
	CD19 is a signaling component of the B-cell receptor complex that lowers the threshold for antigen-driven activation. CD19 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque, cynomolgus-derived CD19 protein, expressed by HEK293 , with C-His labeled tag.

HY-P7838

	CTLA-4 Protein, Cynomolgus (HEK293, His) rCynCytotoxic T-Lymphocyte protein 4/CTLA-4, His; Cytotoxic T-Lymphocyte protein 4; Cytotoxic T-Lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4	Cynomolgus	HEK293
	CTLA-4 Protein, a pivotal inhibitory receptor, is a primary negative modulator of T-cell responses in immune regulation. Its distinctive property lies in significantly higher affinity for B7 ligands (CD80/CD86) than the stimulatory coreceptor CD28. Outcompeting CD28 for ligand engagement, CTLA-4 exerts a suppressive influence on T-cell activation, mitigating excessive immune responses in the intricate landscape of immune regulation. CTLA-4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CTLA-4 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of CTLA-4 Protein, Cynomolgus (HEK293, His) is 124 a.a., with molecular weight of 17-25 kDa.

HY-P76857

	CD19 Protein, Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, His) B-Lymphocyte antigen CD19; CD19; B-Lymphocyte surface antigen B4	Rhesus Macaque	HEK293
	CD19 is a signaling component of the B-cell receptor complex that lowers the threshold for antigen-driven activation. CD19 Protein, Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, His) is the recombinant Rhesus Macaque-derived CD19 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD19 Protein, Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, His) is 272 a.a., with molecular weight of ~31.4 KDa.

HY-P7035

	IL-16 Protein, Human rHuIL-16; Lymphocyte chemoattractant factor; LCF	Human	E. coli
	IL-16 Protein, Human is a proinflammatory cytokine containing 130 amino acids.

HY-P70691

	CTLA-4 Protein, Human (HEK293, GST) Cytotoxic T-Lymphocyte protein 4, Cytotoxic T-Lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4	Human	HEK293
	CTLA-4 Protein, Human (HEK293, GST) is negative regulator of T-cell immune function.

HY-P70684

	CTLA-4 Protein, Human (HEK293, His) Cytotoxic T-Lymphocyte protein 4; Cytotoxic T-Lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4	Human	HEK293
	The CTLA-4 protein is a key inhibitory receptor and a major negative regulator of T cell responses in coordination of immune regulation. Its unique property is its significantly increased affinity for B7 ligands (CD80/CD86) compared with CD28. CTLA-4 Protein, Human (HEK293, His) is the recombinant human-derived CTLA-4 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70706

	CTLA-4 Protein, Mouse (HEK293, Fc) Cytotoxic T-Lymphocyte protein 4; Cytotoxic T-Lymphocyte-associated antigen 4; CTLA-4; CD152; Ctla4	Mouse	HEK293
	CTLA-4 is a key inhibitory receptor that serves as a major negative regulator of T cell responses in immune regulation. Its unique property is that its affinity to B7 ligands (CD80/CD86) is significantly higher than that of CD28. CTLA-4 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CTLA-4 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72363

	CTLA-4 Protein, Human (Biotinylated, HEK293, hFc-Avi) Cytotoxic T-Lymphocyte protein 4; Cytotoxic T-Lymphocyte-associated antigen 4; CTLA-4; CD152	Human	HEK293
	The CTLA-4 protein is a key inhibitory receptor and a major negative regulator of T cell responses in coordination of immune regulation. Its unique property is its significantly increased affinity for B7 ligands (CD80/CD86) compared with CD28. CTLA-4 Protein, Human (Biotinylated, HEK293, hFc-Avi) is the recombinant human-derived CTLA-4 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.

HY-P790057

	LAG-3 Protein, Canine (HEK293, Flag, His) Lymphocyte activating 3	Canine	HEK293
	LAG-3 (lymphocyte activation gene 3) protein is expressed on antigen-activated T cells and transmits inhibitory signals by binding to ligands such as FGL1. FGL1 is the main ligand responsible for the suppressive function of LAG3 T cells. LAG-3 Protein, Canine (HEK293, Flag, His) is the recombinant canine-derived LAG-3 protein, expressed by HEK293 , with C-His, C-Flag labeled tag.

HY-P70505

	CD19 Protein, Human (HEK293, Fc) B-Lymphocyte Antigen CD19; B-Lymphocyte Surface Antigen B4; Differentiation Antigen CD19; T-Cell Surface Antigen Leu-12; CD19	Human	HEK293
	The CD19 protein is a B cell antigen receptor coreceptor that enhances downstream signaling pathways, lowers the activation threshold, and helps B cells respond to antigens. It activates phosphatidylinositol 3-kinase and mobilizes intracellular Ca(2+). CD19 Protein, Human (HEK293, Fc) is the recombinant human-derived CD19 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD19 Protein, Human (HEK293, Fc) is 272 a.a., with molecular weight of ~85.0 kDa.

HY-P71991

	CTLA-4 Protein, Mouse (HEK293, His) Ctla4; Cd152; Cytotoxic T-Lymphocyte protein 4; Cytotoxic T-Lymphocyte-associated antigen 4; CTLA-4; CD antigen CD152	Mouse	HEK293
	CTLA-4 Protein, Mouse (HEK293, His) is a recombinant CTLA-4 protein with a His-flag. CTLA-4 Protein is a single-pass type I membrane protein and belongs to the CD28 receptor family. CTLA-4 is a negative immune regulator constitutively expressed on Treg cells.

HY-P72590

	IL-16 Protein, Mouse (His) Pro-interleukin-16; Interleukin-16; IL-16; Lymphocyte chemoattractant factor; LCF	Mouse	E. coli
	IL-16 Protein, a cytokine, plays a significant role in immune regulation and inflammation. It modulates the activation and migration of various immune cells, such as T cells and monocytes. Understanding the functions of IL-16 Protein can aid in studying immune responses and developing targeted therapies for inflammatory and autoimmune diseases. IL-16 Protein, Mouse (His) is the recombinant mouse-derived IL-16 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-16 Protein, Mouse (His) is 118 a.a., with molecular weight of 14-16 kDa.

HY-P75466

	BTLA/CD272 Protein, Rat (HEK293, mFc) B- and T-Lymphocyte attenuator; CD272; BTLA	Rat	HEK293
	BTLA/CD272 protein inhibits antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. It regulates immune responses through cis and trans interactions with TNFRSF14. In cis, it maintains resting state in naive T cells, while in trans, it supports survival signals in effector T cells. BTLA/CD272 interacts with PTPN6/SHP-1, PTPN11/SHP-2, and TNFRSF14/HVEM. BTLA/CD272 Protein, Rat (HEK293, mFc) is the recombinant rat-derived BTLA/CD272 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of BTLA/CD272 Protein, Rat (HEK293, mFc) is 154 a.a., with molecular weight of ~55-77 kDa.

HY-P75467

	BTLA/CD272 Protein, Mouse (HEK293, hFc) B- and T-Lymphocyte attenuator; CD272; BTLA	Mouse	HEK293
	The BTLA/CD272 protein is expressed on lymphocytes and is a negative regulator of antigen receptor signaling. It interacts with the tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2 to regulate immune responses and maintain lymphocyte homeostasis. BTLA/CD272 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived BTLA/CD272 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of BTLA/CD272 Protein, Mouse (HEK293, hFc) is 147 a.a., with molecular weight of 57-62 kDa.

HY-P7042

	IL-4 Protein, Human (CHO) 3 Publications Verification rHuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra	Human	CHO
	IL-4 Protein, Human (CHO) is a CHO cell derived, potent lymphoid cell growth factor, which stimulates the growth and survivability of B-cells and T-cells.

HY-P7080

	IL-4 Protein, Mouse (CHO) 5+ Cited Publications rMuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra	Mouse	CHO
	IL-4 Protein, Mouse (CHO) is a species-specific cytokine which promotes the proliferation, differentiation and cell-surface protein modulation of B lymphocytes.

HY-P72030

	BTLA/CD272 Protein, Human (HEK293, hFc-Myc) B- and T-Lymphocyte-associated protein; CD272;	Human	HEK293
	The BTLA/CD272 protein is expressed on lymphocytes and is a negative regulator of antigen receptor signaling. It interacts with the tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2 to regulate immune responses and maintain lymphocyte homeostasis. BTLA/CD272 Protein, Human (HEK293, hFc-Myc) is the recombinant human-derived BTLA/CD272 protein, expressed by HEK293 , with C-hFc, C-Myc labeled tag.

HY-P72853

	BLK Protein, Human (sf9, GST) Tyrosine-protein kinase Blk; B Lymphocyte kinase; p55-Blk; BLK	Human	Sf9 insect cells
	The BLK protein is a key non-receptor tyrosine kinase that is essential for B lymphocyte development and signal transduction. It regulates pro-B to pre-B transition, growth arrest, and apoptosis downstream of B cell receptors by binding and phosphorylating CD79A and CD79B. BLK Protein, Human (sf9, GST) is the recombinant human-derived BLK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of BLK Protein, Human (sf9, GST) is 505 a.a., with molecular weight of ~84 kDa.

HY-P73844

	LAG-3 Protein, Mouse (HEK293) Lymphocyte activation gene 3 protein; Protein FDC; CD223	Mouse	HEK293
	LAG-3 (lymphocyte activation gene 3) protein is expressed on antigen-activated T cells and transmits inhibitory signals by binding to ligands such as FGL1.FGL1 is the main ligand responsible for the suppressive function of LAG3 T cells.LAG-3 Protein, Mouse (HEK293) is the recombinant mouse-derived LAG-3 protein, expressed by HEK293 , with tag free.

HY-P76751

	BTLA/CD272 Protein, Rhesus Macaque (HEK293, Fc) B- and T-Lymphocyte attenuator; CD272; BTLA	Rhesus Macaque	HEK293
	BTLA/CD272 Protein, expressed on lymphocytes, is a negative regulator of antigen receptor signaling. Interacting with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, it modulates immune responses and maintains lymphocyte homeostasis. BTLA engages in cis and trans interactions with TNFRSF14; cis interactions regulate naive T cells, inhibiting trans interactions to maintain a resting state. During adaptive immune responses, predominant trans interactions provide survival signals to effector T cells. The intricate interplay highlights BTLA's multifaceted role in immune regulation. BTLA/CD272 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived BTLA/CD272 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of BTLA/CD272 Protein, Rhesus Macaque (HEK293, Fc) is 125 a.a., with molecular weight of ~41.4 KDa.

HY-P76752

	BTLA/CD272 Protein, Rhesus Macaque (HEK293, His) B- and T-Lymphocyte attenuator; CD272; BTLA	Rhesus Macaque	HEK293
	BTLA/CD272 Protein, expressed on lymphocytes, is a negative regulator of antigen receptor signaling. Interacting with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, it modulates immune responses and maintains lymphocyte homeostasis. BTLA engages in cis and trans interactions with TNFRSF14; cis interactions regulate naive T cells, inhibiting trans interactions to maintain a resting state. During adaptive immune responses, predominant trans interactions provide survival signals to effector T cells. The intricate interplay highlights BTLA's multifaceted role in immune regulation. BTLA/CD272 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived BTLA/CD272 protein, expressed by HEK293 , with C-His labeled tag. The total length of BTLA/CD272 Protein, Rhesus Macaque (HEK293, His) is 125 a.a., with molecular weight of ~19.3 KDa.

HY-P7833

	CD19 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) rRhCD19 molecule/CD19, Fc; B-Lymphocyte Antigen CD19; B-Lymphocyte Surface Antigen B4; Differentiation Antigen CD19; T-Cell Surface Antigen Leu-12; CD19	Rhesus Macaque	HEK293
	CD19 is a signaling component of the B-cell receptor complex that lowers the threshold for antigen-driven activation. CD19 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CD19 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P71986

	CTLA-4 Protein, Guinea pig (P.pastoris, His) Cytotoxic T-Lymphocyte associated protein 4; CTLA4	Others	P. pastoris
	CTLA-4 protein, a potent inhibitory receptor, plays a crucial role in suppressing T-cell responses by binding strongly to its ligands CD80 and CD86, surpassing the affinity of CD28. This heightened affinity allows CTLA-4 to act as a major negative regulator, maintaining immune homeostasis and preventing excessive T-cell activation. The balance between CTLA-4 and its ligands is pivotal for immune regulation. CTLA-4 Protein, Guinea pig (P.pastoris, His) is the recombinant CTLA-4 protein, expressed by P. pastoris , with C-6*His labeled tag. The total length of CTLA-4 Protein, Guinea pig (P.pastoris, His) is 125 a.a., with molecular weight of ~18.0 kDa.

HY-P72959

	CTLA-4 Protein, Human (HEK293) Cytotoxic T-Lymphocyte associated protein 4; CTLA4; CD152	Human	HEK293
	The CTLA-4 protein is a key inhibitory receptor and a major negative regulator of T cell responses in coordination of immune regulation. Its unique property is its significantly increased affinity for B7 ligands (CD80/CD86) compared with CD28. CTLA-4 Protein, Human (HEK293) is the recombinant human-derived CTLA-4 protein, expressed by HEK293 , with tag free. The total length of CTLA-4 Protein, Human (HEK293) is 126 a.a., with molecular weight of ~13.5 kDa.

HY-P73843

	LAG-3 Protein, Mouse (HEK293, Fc) Lymphocyte activation gene 3 protein; Protein FDC; CD223	Mouse	HEK293
	LAG-3 (lymphocyte activation gene 3) protein is expressed on antigen-activated T cells and transmits inhibitory signals by binding to ligands such as FGL1.FGL1 is the main ligand responsible for the suppressive function of LAG3 T cells.LAG-3 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived LAG-3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74788

	LAG-3 Protein, Rat (HEK293, His) Lymphocyte activation gene 3 protein; Protein FDC; CD223	Rat	HEK293
	LAG-3 (lymphocyte activation gene 3) protein is an inhibitory receptor on antigen-activated T cells, which transmits inhibitory signals by binding to ligands such as FGL1. LAG-3 is associated with CD3-TCR at the immune synapse, hinders T cell activation, and may cooperate with PDCD1/PD-1 to act as a co-receptor for PD-1. LAG-3 Protein, Rat (HEK293, His) is the recombinant rat-derived LAG-3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77081

	MD-2/LY96 Protein, Mouse (HEK293, Fc) Lymphocyte antigen 96; Ly-96; ESOP-1	Mouse	HEK293
	MD-2/LY96 Protein, acting as a monomer, robustly and specifically binds to interleukin-13 (IL13), distinguishing it from interleukin-4 (IL4) with which it does not interact.This selective binding highlights MD-2/LY96's pivotal role in mediating cellular responses to IL13, underscoring its significance in IL13-related biological activities.MD-2/LY96 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived MD-2/LY96 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P700103AF

	Animal-Free IL-16 Protein, Human (His) Pro-interleukin-16; Interleukin-16; IL-16; Lymphocyte chemoattractant factor; LCF	Human	E. coli
	Animal-Free IL-16 Protein, Human (His) is the recombinant human-derived animal-FreeIL-16 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-16 Protein, Human (His) is 129 a.a., with molecular weight of ~14.12 kDa.

HY-P700104AF

	Animal-Free IL-17A Protein, Human (His) Cytotoxic T-Lymphocyte-associated antigen 8; CTLA-8	Human	E. coli
	The IL-17A protein is an important effector cytokine that is critical in both innate and adaptive immunity to defend against microorganisms and maintain tissue integrity. It acts through the IL17RA-IL17RC heterodimeric receptor complex, triggering signaling pathways, activating immune-related gene transcription and promoting strong immune inflammation. Animal-Free IL-17A Protein, Human (His) is the recombinant human-derived animal-FreeIL-17A protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-17A Protein, Human (His) is 136 a.a., with molecular weight of ~16.47 kDa.

HY-P700186AF

	Animal-Free IL-1 alpha Protein, Mouse (His) Hematopoietin-1; Lymphocyte-Activating Factor (LAF); Endogenous Pyrogen (EP); Leukocyte	Mouse	E. coli
	IL-1 alpha protein is an important cytokine found intracellularly in non-hematopoietic cells that bridges innate and adaptive immunity. Binds to IL1R1 and IL1RAP to form a high-affinity receptor complex, initiates signaling through MYD88, IRAK1 or IRAK4, and activates the NF-kappa-B and MAPK pathways. Animal-Free IL-1 alpha Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-1 alpha protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-1 alpha Protein, Mouse (His) is 156 a.a., with molecular weight of ~18.93 kDa.

HY-P701066

	MD2 Protein, Cynomolgus (His) Lymphocyte antigen 96; LY96; ESOP1; ESOP-1; MD-2	Cynomolgus	E. coli
	MD2 protein binds bacterial lipopolysaccharide (LPS) and collaborates with TLR4 in the innate immune response to LPS. It also interacts with TLR2 in the response to cell wall components from bacteria. MD2 enhances TLR4-dependent NF-kappa-B activation and forms a heterogeneous homomer, participating in a multi-protein complex with CD14 and TLR4. Ligand binding induces complex oligomerization, crucial for the cellular response to LPS. MD2 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived MD2 protein, expressed by E. coli , with C-His labeled tag. The total length of MD2 Protein, Cynomolgus (His) is 142 a.a., with molecular weight of 17.97 kDa.

HY-P701093

	IL-4 Protein, Mouse (HEK293) rMuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra	Mouse	HEK293
	IL-4 Protein, Mouse (HEK293) is a species-specific cytokine which promotes the proliferation, differentiation and cell-surface protein modulation of B lymphocytes.

HY-P71758

	CD20/MS4A1 Protein, Mouse (P.pastoris, His) Ms4a1; Cd20; Ly-44; Ms4a2; B-Lymphocyte antigen CD20; B-cell differentiation antigen Ly-44; Lymphocyte antigen 44; CD antigen	Mouse	P. pastoris
	CD20/MS4A1 protein regulates cellular calcium influx, essential for B-lymphocyte development, differentiation, and activation. It activates store-operated calcium channels, allowing calcium influx through B-cell receptor/BCR activation. CD20/MS4A1 protein forms homotetramers and interacts with cell surface IgM chains, the antigen-binding parts of the BCR. CD20/MS4A1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived CD20/MS4A1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of CD20/MS4A1 Protein, Mouse (P.pastoris, His) is 181 a.a., with molecular weight (glycosylation form) of ~33 kDa.

HY-P74215

	CTLA-4 Protein, Rat (HEK293, His) Cytotoxic T-Lymphocyte associated protein 4; CTLA4; CD152	Rat	HEK293
	CTLA-4 protein inhibits T-cell responses by binding strongly to CD80 and CD86 receptors, surpassing CD28. This affinity allows CTLA-4 to effectively regulate T-cell activation and immune responses. The balance between inhibitory and stimulatory signals controlled by CTLA-4 and its ligands modulates T-cell-mediated immune reactions. CTLA-4 Protein, Rat (HEK293, His) is the recombinant rat-derived CTLA-4 protein, expressed by HEK293 , with C-His labeled tag. The total length of CTLA-4 Protein, Rat (HEK293, His) is 161 a.a., with molecular weight of 21-30 kDa.

HY-P74216

	CTLA-4 Protein, Rat (HEK293, Fc) Cytotoxic T-Lymphocyte associated protein 4; CTLA4; CD152	Rat	HEK293
	CTLA-4 protein inhibits T-cell responses by binding strongly to CD80 and CD86 receptors, surpassing CD28. This affinity allows CTLA-4 to effectively regulate T-cell activation and immune responses. The balance between inhibitory and stimulatory signals controlled by CTLA-4 and its ligands modulates T-cell-mediated immune reactions. CTLA-4 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CTLA-4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CTLA-4 Protein, Rat (HEK293, Fc) is 161 a.a., with molecular weight of ~40.5 kDa.

HY-P75320

	CTLA-4 Protein, Canine (HEK293, His) Cytotoxic T-Lymphocyte associated protein 4; CTLA4; CD152	Canine	HEK293
	CTLA-4 protein inhibits T-cell responses as a critical negative regulator, with a stronger affinity for CD80 and CD86 than CD28. This affinity allows CTLA-4 to effectively suppress T-cell activation and regulate immune responses, maintaining a delicate equilibrium in T-cell-mediated immunity. CTLA-4 Protein, Canine (HEK293, His) is the recombinant canine-derived CTLA-4 protein, expressed by HEK293 , with C-His labeled tag.

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HY-P81619

	BTLA Antibody (YA1364) BTLA; B- and T-Lymphocyte attenuator; B- and T-Lymphocyte-associated protein; CD antigen CD272	FC, ELISA	Human
	BTLA Antibody (YA1364) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1364), targeting BTLA. BTLA Antibody (YA1364) can be used for FC, ELISA experiment in human background.

HY-P80446

	CD19 Antibody (YA543) CD19_HUMAN; B-Lymphocyte antigen CD19; B-Lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD_antigen: CD19; B-Lymphocyte surface antigen B4; Leu 12; Leu12	WB, ICC/IF, IHC-P, FC	Human
	CD19 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 61 kDa, targeting to CD19. It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human.

HY-P80597

	CD19 Antibody (YA807) CD19; B-Lymphocyte antigen CD19; B-Lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD19	ICC/IF, FC	Human
	CD19 Antibody (YA807) is a non-conjugated and Mouse origined monoclonal antibody, targeting to CD19 (3G7). It can be used for ICC/IF,FC assays with tag free, in the background of Human.

HY-P81075

	CTLA4 Antibody CD 152; CD152; CD152 antigen; Celiac disease 3; CELIAC3; CTLA 4; CTLA-4; Cytotoxic T cell associated 4; Cytotoxic T Lymphocyte associated 4; Cytotoxic T Lymphocyte associated antigen 4; Cytotoxic T Lymphocyte associated protein 4; Cytotoxic T Lymphocyte associated serine esterase 4; Cytotoxic T Lymphocyte protein 4; Cytotoxic T-Lymphocyte-associated antigen 4; Cytotoxic T-Lymphocyte-associated protein 4; GSE; IDDM12; CD152 isoform; CTLA4_HUMAN; GRD4; ICOS; Ligand and transmembrane spliced cytotoxic T Lymphocyte associated antigen 4.	WB, ICC/IF	Human, Mouse, Rat
	CTLA4 Antibody is a rabbit-derived non-conjugated IgG antibody, targeting CTLA4, with a predicted molecular weight of 25 kDa. CTLA4 Antibody can be used for WB,ICC/IF experiments in human, mouse, rat backgrounds.

HY-P83306

	Integrin alpha E Antibody (YA3051) Integrin alpha-E; HML-1 antigen; Integrin alpha-IEL; Mucosal Lymphocyte 1 antigen; CD103; ITGAE	IHC-P	Human
	Integrin alpha E Antibody (YA3051) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3051), targeting Integrin alpha E. Integrin alpha E Antibody (YA3051) can be used for IHC-P experiment in human background.

HY-P81344

	LSP1 Antibody (YA1089) Lymphocyte-specific protein 1; Protein pp52; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; 47 kDa actin-binding protein	IHC-P	Human
	LSP1 Antibody (YA1089) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1089), targeting LSP1. LSP1 Antibody (YA1089) can be used for IHC-P experiment in human background.

HY-P81498

	CD103 Antibody (YA1243) Integrin alpha-E; HML-1 antigen; Integrin alpha-IEL; Mucosal Lymphocyte 1 antigen; CD103; ITGAE; Integrin alpha E	IHC-P	Human
	CD103 Antibody (YA1243) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1243), targeting CD103. CD103 Antibody (YA1243) can be used for IHC-P experiment in human background.

HY-P81467

	ICOS Antibody (YA1212) ICOS; AILIM; CD278; Inducible T-cell costimulator; Activation-inducible Lymphocyte immunomediatory molecule	IHC-P	Human
	ICOS Antibody (YA1212) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1212), targeting ICOS. ICOS Antibody (YA1212) can be used for IHC-P experiment in human background.

HY-P81716

	LAG3 Antibody (YA1461) LAG3; FDC; Lymphocyte activation gene 3 protein; LAG-3; Protein FDC; CD223	FC, ELISA	Human
	LAG3 Antibody (YA1461) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1461), targeting LAG3. LAG3 Antibody (YA1461) can be used for FC, ELISA experiment in human background.

HY-P83711M

	Armenian Hamster Anti-Mouse CD80 Antibody (PE) T-Lymphocyte activation antigen CD80; Cd80; Activation B7-1 antigen; B7	FC	Mouse

HY-P82773

	Ly6A/E Antibody (YA2518) Ly-6A.2/Ly-6E.1; Ly6a; Ly6al; Lymphocyte antigen 6A-2/6E-1; Lymphocyte antigen Ly 6A.2/Ly 6E.1; SCA-1; Stem cell antigen 1; T cell activating protein; TAP	WB, IHC-P	Mouse
	Ly6A/E Antibody (YA2518) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2518), targeting Ly6A/E, with a predicted molecular weight of 14 kDa (observed band size: 18 kDa). Ly6A/E Antibody (YA2518) can be used for WB, IHC-P experiment in mouse background.

HY-P81659

	CD5 Antibody (YA1404) CD5; LEU1; T-cell surface glycoprotein CD5; Lymphocyte antigen T1/Leu-1; CD antigen CD5	WB, IHC-P, ICC/IF, IP	Human
	CD5 Antibody (YA1404) is a biotin-conjugated non-conjugated IgG antibody, targeting CD5, with a predicted molecular weight of 55 kDa. CD5 Antibody (YA1404) can be used for WB,IHC-P,ICC/IF,IP experiment in human background.

HY-P83720

	CD5 Antibody (YA3453) CD5; LEU1; T-cell surface glycoprotein CD5; Lymphocyte antigen T1/Leu-1; CD antigen CD5	WB, IHC-P, FC, ELISA	Human, Mouse
	CD5 Antibody (YA3453) is a non-conjugated IgG1 antibody, targeting CD5, with a predicted molecular weight of 55 kDa. CD5 Antibody (YA3453) can be used for WB,IHC-P,FC,ELISA experiment in human，mouse background.

HY-P80722

	IL-4 Antibody (YA343) IL4; Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra	WB	Human, Mouse, Rat
	IL-4 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 17 kDa, targeting to IL-4. It can be used for WB assays with tag free, in the background of Transfected.

HY-P81114

	IL17A Antibody Interleukin-17A; CTLA-8; CTLA 8; CTLA8; Cytotoxic T Lymphocyte associated antigen 8; Cytotoxic T Lymphocyte associated serine esterase 8; IL 17A; IL-17A; IL-17; Interleukin 17; Interleukin-17; Interleukin 17A; Interleukin17; Interleukin17A; IL17_HUMAN; IL17_MOUSE.	WB, ELISA, IHC-P, IHC-F, ICC/IF	Mouse, Rat,
	IL17A Antibody is an unconjugated, approximately 15 kDa, rabbit-derived, anti-IL17A polyclonal antibody. IL17A Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in mouse, rat, background without labeling.

HY-P80607

	CD8 alpha Antibody CD8A; MAL; T-cell surface glycoprotein CD8 alpha chain; T-Lymphocyte differentiation antigen T8/Leu-2; CD antigen CD8a	WB, IHC-P	Human, Hamster
	CD8 alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 26 kDa, targeting to CD8 alpha. It can be used for WB,IHC-P assays with tag free, in the background of Human, Hamster.

HY-P83710M

	Rat Anti-Mouse CD86 Antibody (FITC) T-Lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1	FC	Mouse
	CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

HY-P81366

	CD48 Antibody (YA1111) CD48; BCM1; BLAST1; CD48 antigen; B-Lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; TCT.1; CD48	IHC-P	Human
	CD48 Antibody (YA1111) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1111), targeting CD48. CD48 Antibody (YA1111) can be used for IHC-P experiment in human background.

HY-P81148

	CD8 Antibody CD8 antigen, alpha polypeptide (p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; CD8A_HUMAN; Leu2; Leu2 T Lymphocyte antigen; MAL; OKT8 T cell antigen; p32; T cell antigen Leu2; T cell co receptor; T-cell surface glycoprotein CD8 alpha chain; T-Lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen.	WB, IHC-P, ICC/IF	Mouse
	CD8 Antibody is an unconjugated, approximately 27 kDa, rabbit-derived, anti-CD8 polyclonal antibody. CD8 Antibody can be used for: WB, IHC-P, IHC-F, IF expriments in human, mouse, background without labeling.

HY-P80743

	Lck Antibody (YA712) LCK; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK	WB	Human
	Lck Antibody (YA712) is a non-conjugated and Mouse origined monoclonal antibody about 58 kDa, targeting to Lck (3E5). It can be used for WB assays with tag free, in the background of Human.

HY-P82663

	Interferon Regulatory Factor 4 Antibody (YA2408) IRF4; MUM1; Interferon regulatory factor 4; IRF-4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5	WB, IHC-P, ICC/IF, IP, FC	Human
	Interferon Regulatory Factor 4 Antibody (YA2408) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2408), targeting Interferon Regulatory Factor 4, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). Interferon Regulatory Factor 4 Antibody (YA2408) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human background.

HY-P80609

	CD86 Antibody CD86; CD28LG2; T-Lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86	WB, IHC-P, ICC/IF, IP, FC	Human, Rat
	CD86 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 38 kDa, targeting to CD86. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Rat.

HY-P80602

	CD44 Antibody (YA801) CD44; LHR; MDU2; MDU3; MIC4; CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 Lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycopr	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	CD44 Antibody (YA801) is a non-conjugated and Mouse origined monoclonal antibody about 82 kDa, targeting to CD44 (2H12). It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human.

HY-P81522

	CD22 Antibody (YA1267) CD22; SIGLEC2; B-cell receptor CD22; B-Lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14; CD antigen CD22	IHC-P	Human
	CD22 Antibody (YA1267) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1267), targeting CD22. CD22 Antibody (YA1267) can be used for IHC-P experiment in human background.

HY-P81668

	B7-1 Antibody (YA1413) CD80; CD28LG; CD28LG1; LAB7; T-Lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80	FC, ELISA	Human
	B7-1 Antibody (YA1413) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1413), targeting B7-1. B7-1 Antibody (YA1413) can be used for FC, ELISA experiment in human background.

HY-P81184

	CD80 Antibody (YA3386) Activation B7-1 antigen; B Lymphocyte activation antigen B7; B7; B7-1; B7-1 antigen; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 antigen; CD80 molecule; CD80_HUMAN; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-Lymphocyte activation antigen CD80; CD80_RAT.	WB, IHC-P, FC, ICC/IF	Human, Mouse
	CD80 Antibody is an unconjugated, approximately 30 kDa, mouse-derived, anti-CD80 monoclonal antibody. CD80 Antibody can be used for: WB, IHC-P,FC ICC expriments in mouse,human, and predicted: rat background without labeling.

HY-P80711

	Hsp60 Antibody (YA730) HSPD1; HSP60; 60 kDa heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 Lymphocyte protein	WB, ICC/IF, IP	Human, Mouse, Rat
	Hsp60 Antibody (YA730) is a non-conjugated and Mouse origined monoclonal antibody about 61 kDa, targeting to Hsp60 (6C8). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P83008

	IL-12 beta Antibody (YA2753) IL12B; NKSF2; Interleukin-12 subunit beta; IL-12B; Cytotoxic Lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; NKSF2	WB	Human
	IL-12 beta Antibody (YA2753) is a biotin-conjugated non-conjugated IgG antibody, targeting IL-12 beta, with a predicted molecular weight of 37 kDa (observed band size: 40 kDa). IL-12 beta Antibody (YA2753) can be used for WB experiment in human background.

HY-P80763

	NF-KB p100 Antibody NFKB2; LYT10; Nuclear factor NF-kappa-B p100 subunit; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; Oncogene Lyt-10; Lyt10	WB, ICC/IF, IP	Human, Mouse, Rat
	NF-KB p100 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 97 kDa, targeting to NF-KB p100. It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P81765

	BAFF Antibody (YA1510) TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B Lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD257	FC, ELISA	Human
	BAFF Antibody (YA1510) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1510), targeting BAFF. BAFF Antibody (YA1510) can be used for FC, ELISA experiment in human background.

HY-P81150

	GPR30 Antibody G Protein Coupled Receptor 30; G-protein coupled receptor 30; G-protein coupled estrogen receptor 1; Membrane estrogen receptor; mER; Chemokine receptor-like 2; IL8-related receptor DRY12; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; Lymphocyte-derived G-protein coupled receptor; LYGPR; GPCR-BR; CEPR; CMKRL2; DRY12; GPER.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF,	Human, Mouse, Rat
	GPR30 Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-GPR30 polyclonal antibody. GPR30 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, and predicted: chicken, cow, horse, rabbit background without labeling.

HY-P83701

	HLA E Antibody (YA3437) HLA class I histocompatibility antigen E alpha chain antibody; EA1.2 antibody; EA2.1 antibody; HLA 6.2 antibody; HLA class I histocompatibility antigen alpha chain E antibody; HLA class I histocompatibility antigen E alpha chain precursor antibody; HLA class I histocompatibility antigen E alpha chain precursor antibody; HLA6.2 antibody; HLAE antibody; Lymphocyte antigen antibody; Major histocompatibility complex class I E antibody; MHC antibody; MHC class I antigen E antibody; MHC HLA E alpha 1 antibody; MHC HLA E alpha 2.1 antibody; QA1 antibody	WB, IP, FC	Human
	HLA E Antibody is a non-conjugated and Mouse origined monoclonal antibody about 40 kDa, targeting to HLA E . It can be used for WB, IP, FC assays with tag free, in the background of Human.

HY-P81083

	ADGRE1 (F4/80) Antibody (YA920) F4/80 (mouse); Adhesion G protein-coupled receptor E1; Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone receptor like 1; Egf like module containing mucin like hormone receptor like sequence 1; EGF like module receptor 1; EGF TM7; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGFTM7; EMR 1; EMR1; EMR-1; EMR1 hormone receptor; EMR1_HUMAN; AGRE1_HUMAN; Gpf480; Ly71; Lymphocyte antigen 71; TM7LN3.	WB, IHC-P, IHC-F, ICC/IF	Mouse, Rat
	ADGRE1 (F4/80) Antibody (YA920) is an unconjugated, approximately 102 kDa, rabbit-derived, anti-ADGRE1 (F4/80) (YA920) monoclonal antibody. ADGRE1 (F4/80) Antibody (YA920) can be used for: WB, IHC-P, IF-Tissue, IHC-Fr expriments in mouse, rat background without labeling.

HY-P81143

	CCR7 Antibody CCR7_HUMAN; BLR 2; BLR2; C C chemokine receptor type 7; C C CKR 7; CC chemokine receptor 7; CC chemokine receptor type 7; CC CKR 7; CCCKR7; CCR 7; CD 197; CD197; CD197 antigen; CDW197; Chemokine C C motif receptor 7; Chemokine C C receptor 7; Chemokine receptor 7-like protein; EBI 1; EBI1; Ebi1h; EBV Induced G Protein Coupled Receptor 1; Epstein Barr virus induced G protein coupled receptor; Epstein Barr virus induced gene 1; EVI 1; EVI1; Lymphocyte Specific G Protein Coupled Peptide Receptor; MGC108519; MIP 3 beta receptor; MIP3 Beta Receptor.	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	CCR7 Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-CCR7 polyclonal antibody. CCR7 Antibody can be used for: WB, ELISA, IHC-P, ICC, IF expriments in human, mouse, rat, and predicted: dog background without labeling.

HY-P80062

	CD44 Antibody LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule (Indian blood group) antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; Cell surface glycoprotein CD44 antibody; chondroitin sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 Lymphocyte homing/adhesion receptor antibody; HCELL antibody; hematopoietic cell E- and L-selectin ligand antibody; Heparan sulfate proteoglycan antibody; Hermes antigen antibody; homing function and Indian blood group system antibody; HSA antibody; HUTCH-I antibody; HUTCH1 antibody; Hyaluronate receptor antibody; IN antibody; MC56 antibody; MDU2 antibody; MDU3 antibody; MGC10468 antibody; MIC4 antibody; MUTCH1 antibody; PGP-1 antibody; PGP-I antibody; PGP1 antibody; Phagocytic glycoprotein 1 antibody; Phagocytic glycoprotein I antibody; Soluble CD44 antibody;	WB, IHC-P, FC	Human, Mouse
	CD44 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 82 kDa, targeting to CD44. It can be used for WB,IHC-P,FC assays with tag free, in the background of Human, Mouse.

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Cat. No.	Product Name		Classification

HY-153209

ISATM51		Adjuvant
ISATM51 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses .

HY-160055

GMT 4 aptamer sodium		Aptamers
GMT 4 aptamer sodium is a nucleic acid aptamer targeting different glioblastoma cell lines and exhibits high affinity. GMT 4 aptamer sodium also shows high binding affinity to the T lymphocyte cell line CCRF-CEM .

HY-160057

GMT 8 aptamer sodium		Aptamers
GMT 8 aptamer sodium is a nucleic acid aptamer targeting different glioblastoma cell lines and exhibits high affinity. GMT 4 aptamer sodium also shows high binding affinity to the T lymphocyte cell line CCRF-CEM .

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