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C2

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780

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7

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8

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37

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31

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220

Isotope-Labeled Compounds

14

Antibodies

58

Click Chemistry

36

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101180
    C2 Ceramide
    1 Publications Verification

    Ceramide 2

    		 Phosphatase Mitochondrial Metabolism Apoptosis Autophagy Metabolic Disease Endocrinology
    C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis, inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss [2] .
    C2 Ceramide
  • HY-W590664
    C2 Dihydroceramide

    		Endogenous Metabolite Cardiovascular Disease
    C2 Dihydroceramide is a derivative of C2 Ceramide (HY-101180). C2 Dihydroceramide enhances the ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I) without causing cytotoxicity .
    C2 Dihydroceramide
  • HY-W590667
    C2 Ceramide-1-phosphate

    		Biochemical Assay Reagents Others
    C2 Ceramide-1-phosphate is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. C2 Ceramide-1-phosphatecan be used in drug delivery research .
    C2 Ceramide-1-phosphate
  • HY-165072
    C2 3'-Sulfo galactosylceramide (d18:1/2:0)

    C2 Sulfatide; N-Acetyl sulfatide

    		 Others Others
    C2 3'-Sulfo galactosylceramide (d18:1/2:0) (C2 Sulfatide) is one of the sulfatide class of glycolipids. C2 3'-Sulfo galactosylceramide (d18:1/2:0) can be used in the quantification of lysosulfatides in mouse brain tissue and plasma .
    C2 3'-Sulfo galactosylceramide (d18:1/2:0)
  • HY-RS01738
    C2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    C2 Human Pre-designed siRNA Set A contains three designed siRNAs for C2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C2 Human Pre-designed siRNA Set A
    C2 Human Pre-designed siRNA Set A
  • HY-166226
    C2 Sphingomyelin (d18:1/2:0)

    		Biochemical Assay Reagents Metabolic Disease
    C2 Sphingomyelin (d18:1/2:0) is an ester product.
    C2 Sphingomyelin (d18:1/2:0)
  • HY-116877
    C2 Ceramide (d14:1/2:0)

    		COX Cancer
    C2 Ceramide (d14:1/2:0) is a composition for diagnosing diseases associated with cyclooxygenase 2 (COX2) overexpression. C2 Ceramide (d14:1/2:0) exhibits a strong binding activity to COX2 protein (extracted from patent WO2019235824A1).
    C2 Ceramide (d14:1/2:0)
  • HY-131992
    N-Acetylpsychosine

    C2 Galactosylceramide (d18:1/2:0)

    		 Apoptosis Inflammation/Immunology
    N-Acetylpsychosine (C2 Galactosylceramide (d18:1/2:0)), α-galactosylated C2-ceramide, has immunostimulatory activity. N-Acetylpsychosine can be a useful tool to investigate the mechanism of apoptosis and the immune reponses induced by dendritic cells (DCs) .
    N-Acetylpsychosine
  • HY-165064
    C2 L-Erythro ceramide (d18:1/2:0)

    L-Erythro cer(d18:1/2:0); N-Acetyl-L-erythro-sphingosine; Acetyl-L-erythro-sphingosine

    		 Others Cancer
    C2 L-Erythro ceramide (d18:1/2:0) is a cell-permeable sphingolipid. C2 L-Erythro ceramide (d18:1/2:0) induces cell cycle arrest in the G0/G1 phase and inhibits cell growth [2].
    C2 L-Erythro ceramide (d18:1/2:0)
  • HY-124273
    C2 L-threo Ceramide (d18:1/2:0)

    L-threo Cer(d18:1/2:0); L-threo Ceramide (d18:1/2:0); N-acetyl-L-threo-Sphingosine

    		 Endogenous Metabolite Cardiovascular Disease
    C2 L-threo Ceramide (d18:1/2:0) (L-threo Cer(d18:1/2:0); L-threo Ceramide (d18:1/2:0)) is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide. C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.
    C2 L-threo Ceramide (d18:1/2:0)
  • HY-163078
    C2-Gal-Dox

    		Drug Derivative Cancer
    C2-Gal-Dox is a galactose conjugate with high cytotoxicity. C2-Gal-Dox inhibits the growth of a variety of cancer cells .
    C2-Gal-Dox
  • HY-141323
    C2-Bis-phosphoramidic acid diethyl ester

    		PROTAC Linkers Cancer
    C2-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    C2-Bis-phosphoramidic acid diethyl ester
  • HY-148472A
    C2-Amide-C4-NH2

    		ADC Linker Others
    C2-Amide-C4-NH2 is a potent linker .
    C2-Amide-C4-NH2
  • HY-RS01742
    C2orf69 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    C2orf69 Human Pre-designed siRNA Set A contains three designed siRNAs for C2orf69 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C2orf69 Human Pre-designed siRNA Set A
    C2orf69 Human Pre-designed siRNA Set A
  • HY-RS01741
    C2CD5 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    C2CD5 Human Pre-designed siRNA Set A contains three designed siRNAs for C2CD5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C2CD5 Human Pre-designed siRNA Set A
    C2CD5 Human Pre-designed siRNA Set A
  • HY-RS01740
    C2CD3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    C2CD3 Human Pre-designed siRNA Set A contains three designed siRNAs for C2CD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C2CD3 Human Pre-designed siRNA Set A
    C2CD3 Human Pre-designed siRNA Set A
  • HY-N12447
    C-2′-Decoumaroylaloeresin G

    		Others Others
    1059182-21-6
    C-2′-Decoumaroylaloeresin G
  • HY-103708
    Nezukone

    C2-deoxyhinokitiol; 4-Isopropyltropone

    		 Drug Derivative Others
    Nezukone is a derivative of hinokitiol. Hinokitiol can restore iron transports, however, Nezukone cannot bind or transport iron.
    Nezukone
  • HY-P99163
    Tilavonemab

    ABBV-8E12; C2N-8E12

    		 Tau Protein Neurological Disease
    Tilavonemab (ABBV-8E12) is a humanized anti-tau antibody that targets the extracellular form of pathological tau protein aggregates by binding to the N-terminal 25-30 amino acid residues of tau protein. Tilavonemab blocks the ability of human and mouse neurons to take up tau aggregates, reduces the loss of brain volume, slows the progression of tau pathology, and improves cognitive abilities in transgenic mice expressing mutant human tau. Tilavonemab is used in Alzheimer's disease research [2] .
    Tilavonemab
  • HY-138083
    Parvodicin C2

    		Bacterial Antibiotic Infection
    Parvodicin C2 is a glycopeptide antibiotic that can be isolated from parvosata. Parvodicin C2 has antibacterial activity .
    Parvodicin C2
  • HY-N1517A
    (Rac)-Ganoderic acid C2

    		Aldose Reductase Cancer
    (Rac)-Ganoderic acid C2 is the racemate of Ganoderic acid C2 (HY-N1517). Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses anti-tumor, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM[ [2].
    (Rac)-Ganoderic acid C2
  • HY-N12297
    Ciwujianoside C2

    		Lipase Others
    Ciwujianoside C2 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C2 enhances pancreatic lipase activity in vitro .
    Ciwujianoside C2
  • HY-N7521
    Procyanidin C2

    Procyanidine C2

    		 Others Others
    Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .
    Procyanidin C2
  • HY-N1517R
    Ganoderic acid C2 (Standard)

    		Aldose Reductase Cancer
    Ganoderic acid C2 (Standard) is the analytical standard of Ganoderic acid C2. This product is intended for research and analytical applications. Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM [2].
    Ganoderic acid C2 (Standard)
  • HY-N1517
    Ganoderic acid C2

    		Aldose Reductase Cancer
    Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM [2].
    Ganoderic acid C2
  • HY-W777012
    Acridinium C2 NHS ester

    		Fluorescent Dye
    Acridinium C2 NHS ester is a chemiluminescent label that is active for the development of protein and nucleic acid probes. Acridinium C2 NHS ester can be used in bioanalysis and diagnostics to provide highly sensitive detection solutions. Acridinium C2 NHS ester is widely used in medical research, especially in the monitoring and analysis of biomolecules.
    Acridinium C2 NHS ester
  • HY-126830
    Antifolate C2

    		Antifolate Apoptosis Cancer
    Antifolate C2 is an anti-folate compound that has inhibitory effects on the proliferation of non-squamous non-small cell lung cancer (NS-NSCLC). Antifolate C2 achieves tumor selectivity by targeting proton-coupled folate transporter (PCFT), which is more selective to PCFT than the commonly used anti-folate drug Pemetrexed (HY-10820). Antifolate C2 blocks the biosynthesis of deoxypurine nucleotides by inhibiting glycinamide ribonucleotide formyltransferase (GARFTase), ultimately inhibiting the proliferation of tumor cells. Antifolate C2 can be used in studies of NS-NSCLC, especially in patients who do not respond well to Pemetrexed .
    Antifolate C2
  • HY-130155
    AMPK activator C2

    		AMPK Neurological Disease
    AMPK activator C2 is a potent allosteric AMPK activator that is promising for research of epilepsy and convulsions .
    AMPK activator C2
  • HY-N6910
    Pseudolaric Acid C2

    		Others Metabolic Disease
    Pseudolaric Acid C2, a diterpenoid isolated from Pseudolarix kaempferi, is identified as the specific metabolite of Pseudolaric acid B in plasma, urine, bile and feces after both oral and intravenous administration to rats [2].
    Pseudolaric Acid C2
  • HY-169480
    Lipid C2

    		Liposome Infection Cancer
    Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3 +CD8 + central and CD3 +CD8 + effector memory T cells and decrease the percentage of CD3 + T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model .
    Lipid C2
  • HY-135868
    Mito-apocynin (C2)

    		Mitochondrial Metabolism Neurological Disease
    Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect .
    Mito-apocynin (C2)
  • HY-N6980
    Licorice glycoside C2
    1 Publications Verification

    		 HIV Infection Cancer
    Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .
    Licorice glycoside C2
  • HY-48394A
    Bis-S-C2-N(N-Me)-C2-OH dihydrochloride

    		Drug Derivative Others
    Bis-S-C2-N(N-Me)-C2-OH (dihydrochloride) is an active compound. Bis-S-C2-N(N-Me)-C2-OH (dihydrochloride) can be used for various biochemical studies.
    Bis-S-C2-N(N-Me)-C2-OH dihydrochloride
  • HY-130713
    Thalidomide-C2-amido-C2-COOH

    		E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-C2-amido-C2-COOH incorporates a CRBN ligand for the E3 ubiquitin ligase, and a linker. Thalidomide-C2-amido-C2-COOH can be used to design PROTAC CDK2/9 Degrader-1 (HY-130709) .
    Thalidomide-C2-amido-C2-COOH
  • HY-148080
    Indole-C2-amide-C2-NH2

    		ADC Linker Others
    Indole-C2-amide-C2-NH2 is a potent linker .
    Indole-C2-amide-C2-NH2
  • HY-130436
    Acid-C2-PEG4-C2-NHS ester

    		PROTAC Linkers Cancer
    Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Acid-C2-PEG4-C2-NHS ester
  • HY-161191
    Thalidomide-azetidine-piperazine-C2-O-C2-OH

    		Ligands for E3 Ligase Autophagy Cancer
    Thalidomide-azetidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-azetidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
    Thalidomide-azetidine-piperazine-C2-O-C2-OH
  • HY-140127
    Azide-C2-SS-C2-biotin

    		ADC Linker Cancer
    Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azide-C2-SS-C2-biotin
  • HY-140101
    Azido-C2-SS-PEG2-C2-acid

    		ADC Linker Cancer
    Azido-C2-SS-PEG2-C2-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-C2-SS-PEG2-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-C2-SS-PEG2-C2-acid
  • HY-157759
    (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH

    		Ligands for E3 Ligase Autophagy Cancer
    (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN proteins and serve as a key intermediate for the synthesis of complete PROTAC molecules.
    (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH
  • HY-123439
    FTY720-C2

    		Others Neurological Disease
    FTY720-C2 is a derivative of FTY72 (HY-12005). FTY720-C2 promotes the expression of brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) in multiple system atrophy (MSA) models, without causing immunosuppression. FTY720-C2 improves motor dysfunction and reduces the levels of insoluble alpha-synuclein (αSyn) in MSA mouse models. FTY720-C2 is blood-brain barrier penetrate .
    FTY720-C2
  • HY-N3671
    Cycloshizukaol A

    		Others Others
    Cycloshizukaol A is a symmetrical cyclic lindenane dimer with C2 symmetry. Cycloshizukaol A can be isolated from the root of Chloranthus serratus .
    Cycloshizukaol A
  • HY-164210
    DBCO-PEG2-C2-acid

    		ADC Linker Cancer
    DBCO-PEG2-C2-acid is an ADC Linker. DBCO-PEG2-C2-acid can be used to synthesize Antibody-Drug Conjugates (ADCs) .
    DBCO-PEG2-C2-acid
  • HY-168723
    Piperidine-C-Pip-C2-Pip-C2-OH

    		PROTAC Linkers Cancer
    Piperidine-C-Pip-C2-Pip-C2-OH is a PROTAC Linker that can be used to synthesize the PROTAC PARP1 degrader-3 (HY-168722) for tumor research .
    Piperidine-C-Pip-C2-Pip-C2-OH
  • HY-169437
    Nitro-Naphthalimide-C2-acylamide

    		DNA Alkylator/Crosslinker Cancer
    Nitro-Naphthalimide-C2-acylamide is a DNA intercalator. Nitro-Naphthalimide-C2-acylamide can be used for the synthesis of PROTAC-like Naph-Se-TMZ (HY-169433) .
    Nitro-Naphthalimide-C2-acylamide
  • HY-115384
    Amino-PEG5-C2-acid

    		ADC Linker PROTAC Linkers Cancer
    Amino-PEG5-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    Amino-PEG5-C2-acid
  • HY-W040165
    Amino-PEG3-C2-acid

    		ADC Linker PROTAC Linkers Cancer
    Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG3-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Amino-PEG3-C2-acid
  • HY-135928
    Biotin-C2-S-S-pyridine

    		ADC Linker Cancer
    Biotin-C2-S-S-pyridine is a cleavable ADC linker. Biotin-C2-S-S-pyridine can be used in the synthesis of antibody-drug conjugates (ADCs) .
    Biotin-C2-S-S-pyridine
  • HY-168244
    TsO-C2-Piperidine-O-azetidine-CO-Ph-C2-OH

    		PROTAC Linkers Cancer
    TsO-C2-Piperidine-O-azetidine-CO-Ph-C2-OH is a PROTAC linker, and can be used for PROTAC synthesis, such as PROTAC BRM/BRG1 degrader-1 (HY-168242) .
    TsO-C2-Piperidine-O-azetidine-CO-Ph-C2-OH
  • HY-148484
    Pomalidomide-5'-PEG5-C2-COOH

    		Drug Derivative Others
    Pomalidomide-5'-PEG5-C2-COOH is an active compound. Pomalidomide-5'-PEG5-C2-COOH can be used for the research of various biochemical .
    Pomalidomide-5'-PEG5-C2-COOH

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