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Gram-negative

" in MedChemExpress (MCE) Product Catalog:

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100577

Ticarcillin sodium 3 Publications Verification	Bacterial Antibiotic	Infection
Ticarcillin sodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections .

HY-103095

Enmetazobactam 5 Publications Verification AAI101	Beta-lactamase Bacterial	Infection
Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor, against many resistant Gram-negative pathogens .

HY-A0246A

Flucloxacillin sodium 1 Publications Verification	Bacterial Antibiotic	Infection
Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria .

HY-164036

Lolamicin	Antibiotic Bacterial	Infection
Lolamicin is a Gram-negative specific antibiotic. Lolamicin is active against more than 130 multidrug-resistant clinical isolates, has shown efficacy in multiple mouse models of acute pneumonia and sepsis infection, and protects the gut microbiome of mice against secondary infection with Clostridium difficile. The selective killing of pathogenic gram-negative bacteria by Lolamicin is a result of the low sequence homology of pathogenic bacteria and symbiotic bacteria. Lolamicin can be used in the study of infection caused by Gram-negative pathogens .

HY-139748

ETX0462	Antibiotic Bacterial	Infection
ETX0462 is a gram-negative chemotype antibiotic. ETX0462 has potent in vitro and in vivo activity against Pseudomonas aeruginosa plus all other Gram-negative ESKAPE pathogens, Stenotrophomonas maltophilia and biothreat pathogens .

HY-130581

Lipid X	Bacterial Antibiotic	Infection
Lipid X is a novel monosaccharide precursor of Lipid A (the active moiety of gram-negative endotoxin). Lipid X is protective against endotoxin administered to mice and sheep and against life-threatening gram-negative infections in mice .

HY-A0246

Flucloxacillin	Antibiotic Bacterial	Infection
Flucloxacillin is an active antibiotic against gram-positive and gram-negative bacteria .

HY-158682

LpxC-IN-13	Bacterial	Infection
LpxC-IN-13 (Compound 13) is a LpxC inhibitor, with an IC₅₀ 18.06 nM. LpxC-IN-13 effectively inhibits Gram-negative bacterial infection .

HY-121347

Enterocin Vulgamycin	Antibiotic Bacterial	Inflammation/Immunology
Enterocin, an antibiotic, has static activities against gram-positive and gram-negative bacteria and no activity against fungi and yeast .

HY-103095A

Enmetazobactam iodide AAI101 iodide	Bacterial Antibiotic	Others
Enmetazobactam (iodide) (AAI101 (iodide)) is an extended-spectrum β-lactamase inhibitor, against many resistant Gram-negative pathogens .

HY-P1649B

SPR741 acetate 3 Publications Verification NAB741 acetate	Bacterial Antibiotic	Infection
SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate .

HY-P1649

SPR741 NAB741	Bacterial Antibiotic	Infection
SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 .

HY-P2523

Temporin L	Bacterial Fungal	Infection
Temporin L is a potent antimicrobial peptide and is active against Gram-negative bacteria and yeast strains. Temporin L also has antiendotoxin properties .

HY-A0253

Cefacetrile Cephacetrile; Cephacetril	Bacterial Antibiotic	Infection
Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection .

HY-P1649A

SPR741 TFA NAB741 TFA	Bacterial Antibiotic	Infection
SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 TFA inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA .

HY-W749146

Raja 42	Antibiotic Bacterial	Infection
Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains .

HY-149309

Topoisomerase inhibitor 2	Topoisomerase	Infection
Topoisomerase inhibitor 2 (18C) is a bacterial topoisomeraseinhibitor that exhibits potent broad-spectrum activity against multidrug-resistant Gram-negative bacteria .

HY-P10546

Polyalanine peptide pALA	Bacterial	Infection
Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research .

HY-W002677

Fluoroquinolonic acid	Antibiotic Bacterial	Infection
Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria .

HY-122071

Bicyclomycin	Antibiotic Bacterial	Infection
Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa .

HY-B0875B

Cefmenoxime sodium SCE-1365 sodium	Antibiotic Bacterial	Infection
Cefmenoxime sodium is a new semisynthetic cephalosporin antibiotic. Cefmenoxime sodium has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-157315

Fabl inhibitor 21272541	Bacterial	Infection
21272541 is a potent inhibitor of FabI protein. 21272541 significantly inhibits the infections caused by Gram-negative organisms .

HY-Q50147

Antimicrobial agent-21	Bacterial	Infection
Antimicrobial agent-21 (Compound IIm) is a bacterial inhibitor. Antimicrobial agent-21 is active against gram-positive and gram-negative bacterial .

HY-N3640

Crenatine	Bacterial	Infection
Crenatine is an antibacterial agent. Crenatine is more effective against *Gram-positive* than *Gram-negative* bacteria .

HY-W040128

Kanamycins sulfate	Antibiotic Bacterial	Infection
Kanamycins sulfate is a broad-spectrum antibiotic, can be used in certain severe staphylococcal or Gram-negative bacillary infections. Kanamycin sulfate has certain ototoxicity .

HY-163887

PBZ1038	Bacterial	Infection
PBZ1038 is a highly effective inhibitor of Gram-negative chaperone proteins, achieving its antibacterial effect by inhibiting GroES/GroEL .

HY-B0525

Carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-145440

Colistin adjuvant-2	Bacterial	Infection
Colistin adjuvant-2 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria .

HY-B0875

Cefmenoxime hydrochloride SCE-1365 hydrochloride	Antibiotic Bacterial	Infection
Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-B0875A

Cefmenoxime SCE-1365	Antibiotic Bacterial	Infection
Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-B1174

Bekanamycin Kanamycin B	Antibiotic Bacterial	Infection
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-142127

Ribostamycin Vistamycin; SF-733	Bacterial Antibiotic PDI	Infection
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .

HY-P5555

LMW peptide	Bacterial	Infection
LMW peptide is an antimicrobial peptide. LMW peptide is active against Gram-positive and Gram-negative bacterial, such as B. subtilis, L. monocytogenes, E. coli, P. aeruginosa, V. cholera .

HY-B0525A

Carbenicillin disodium 4 Publications Verification Sodium carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-P10228

S-Thanatin	Fungal Bacterial	Infection
S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na ⁺/K ⁺) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner .

HY-145158

Temocillin	Bacterial Antibiotic	Infection
Temocillin, a 6-alpha-methoxy penicillin derivative, is a semisynthetic beta-lactam antibiotic with a spectrum of activity against most aerobic Gram-negative bacteria .

HY-N12262

(+)-Epieudesmin	Bacterial	Infection Cancer
(+)-Epieudesmin is an antineoplastic agent. (+)-Epieudesmin has marginal cancer cell line inhibitory activities. (+)-Epieudesmin inhibits the growth of *Gram-negative* pathogen .

HY-114938

Fumaramidmycin	Antibiotic Bacterial	Infection
Fumaramidmycin is an antibiotic found in Streptomyces kurssanovii NR-7GG1. Fumaramidmycin shows an antimicrobial activity against both *Gram-positive* and Gram-negative bacteria .

HY-116271

Sperabillin C	Antibiotic Bacterial	Infection
Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus .

HY-106922A

Sanfetrinem sodium GV104326 sodium	Antibiotic Bacterial	Infection
Sanfetrinem (GV104326) sodium is a beta-lactamase-stable antibiotic. Sanfetrinem sodium has broad-spectrum activity against gram-positive and gram-negative bacteria .

HY-122394

Thiolactomycin	Antibiotic Bacterial	Infection
Thiolactomycin is an antibiotic. Thiolactomycin is active against Gram-negative anaerobes. Thiolactomycin also inhibits malaria and trypanosomes. Thiolactomycin is a FabB inhibitor. Thiolactomycin inhibits the synthesis of fatty acids and mycolic acids .

HY-P4816

Pseudin-2	Bacterial Fungal	Infection Inflammation/Immunology
Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria .

HY-B2170

Octenidine	Bacterial	Infection
Octenidine is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine can inhibit the expression of biofilm genes and destroy the formation of biofilms .

HY-B0187A

Doripenem monohydrate 5 Publications Verification S 4661 monohydrate	Bacterial Antibiotic	Infection
Doripenem (S 4661) monohydrate, a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria .

HY-B0187

Doripenem 5 Publications Verification S 4661	Bacterial Antibiotic	Infection
Doripenem (S 4661), a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria .

HY-105180

Lenapenem BO-2727 free acid	Bacterial	Infection
Lenapenem (BO-2727 free acid), a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa .

HY-113678

Colistin Polymyxin E	Antibiotic Bacterial	Infection
Colistin (Polymyxin E) is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli .

HY-N10097

Chamigrenol	Na+/K+ ATPase Bacterial	Infection
Chamigrenol is a Na ⁺/K ⁺-ATPase inhibitor with an IC₅₀ value of 15.9 μg/mL. Chamigrenol shows strong inhibitory activities against *Gram-positive* and Gram-negative bacteria except Escherichia coli, with MIC values of 50 µg/mL .

HY-D1697

OGDA	Fluorescent Dye	Infection
OGDA is a green fluorescent D-amino acid. OGDA is suitable for labeling peptidoglycan in Gram-positive and Gram-negative bacteria .

HY-P2794

G0775	Bacterial	Infection Neurological Disease Inflammation/Immunology
G0775 is a molecule with potent, broad-spectrum activity against Gram-negative bacteria. G0775 is active against MDR bacteria. G0775 binds the LepB protease domain .

Cat. No.	Product Name	Type

HY-D2208

SYTM Green	Fluorescent Dyes/Probes
SYTM Green is a permeable DNA dye that fluoresces green by binding to dsDNA (Ex/Em=503/530 nm). SYTM Green can also be used to stain bacteria, including Gram-positive and Gram-negative bacteria. Note: SYTM Green cannot penetrate living cells, and this product is equivalent to SYTOX Green .

HY-43520

BODIPY-FL

Fluorescent Dyes/Probes

BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. BODIPY-FL-labeled sphingolipid analogs can be used to investigate sphingolipid internalization, transport, and endocytosis in mouse embryonic stem cells. BODIPY-FL-labeled monoterpenes can quickly penetrate bacteria, mammalian, and fungal cells, allowing for the detection of characteristics of a broad spectrum of Gram-positive and Gram-negative bacteria, as well as pathogenic fungi. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Fluorescent Dye

Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

Cat. No.	Product Name	Type

HY-W016473

Adamantane-carboxylic acid	Biochemical Assay Reagents
Adamantane-carboxylic acid is an antibacterial agent that is effective in inhibiting the growth of Gram-positive bacteria but is less sensitive to Gram-negative bacteria .

HY-NP023

Lactoferrin (human) CKRX; GIG12	Native Proteins
Lactoferrin (human) is an iron-binding protein. Lactoferrin (human) has antimicrobial activity against a wide range of microorganisms, including *Gram-positive* and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin (human) can be used to culture mutans Streptococcus in iron-restricted medium .

HY-D1056

Lipopolysaccharides, from E. coli O55:B5

245+ Cited Publications

LPS

Carbohydrates

Lipopolysaccharides, from E. coli O55:B5 (LPS, from Escherichia coli (O55:B5)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O55:B5) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O55:B5 possess the typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activate TLR-4 in immune cells, exhibit high pyrogenicity, and demonstrate dose and serotype specificity. Lipopolysaccharides, from E. coli O55:B5 can cause multiphasic and non-dose-dependent increases in body temperature in rats .

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Biochemical Assay Reagents

HY-W354851

Pisiferic acid	Biochemical Assay Reagents
Pisiferic acid is an antibacterial agent with inhibitory activity against Gram-negative/positive bacteria such as P. vulgaris, S. aureus and B. subtilis. Pisiferic acid can be used to study bacterial infections .

HY-W740053

Meropenem sodium	Microbial Culture
Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

Cat. No.	Product Name

HY-K1044

Polymyxin B (1,000×), Sterile

Polymixin B is a mixture of B1 and B2 polypeptides obtained from different strains of Bacillus polymyxa, with antibacterial activity against gram-negative bacteria. It can bind lipopolysaccharide (LPS) of the outer membrane of gram-negative bacteria and disrupts the cytoplasmic membrane by inducing large pores to allow nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.

HY-K1006

Penicillin-Streptomycin (100×), Sterile 35+ Cited Publications
MCE MCE Penicillin-Streptomycin (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria.

HY-K1010

Penicillin-Streptomycin-Glutamine (100×), Sterile
MCE Penicillin-Streptomycin-Glutamine (100×), sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria.

HY-K1050

Gentamicin, Sterile
MCE Gentamicin, Sterile acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria, mainly for gram-negative and gram-positive bacteria.

HY-K0014

Penicillin-Streptomycin-Neomycin (PSN) (100×), Sterile
MCE Penicillin-Streptomycin-Neomycin (PSN) (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria.

HY-K1008

Gentamicin-Amphotericin B (500×), Sterile 1 Publications Verification
MCE Gentamicin-Amphotericin B (500×), sterile is used to prevent contamination of cell culture due to their effective combined action against gram-positive bacteria, gram-negative bacteria, fungi and yeasts.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1174

Bekanamycin Kanamycin B	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-122071

Bicyclomycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa .

HY-N3640

Crenatine	Structural Classification Alkaloids Simaroubaceae Source classification Plants Quassia undulata (Guill. & Perr.) D.Dietr. Indole Alkaloids	Bacterial
Crenatine is an antibacterial agent. Crenatine is more effective against *Gram-positive* than *Gram-negative* bacteria .

HY-142127

Ribostamycin Vistamycin; SF-733	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic PDI
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .

HY-N12262

(+)-Epieudesmin	Structural Classification other families Hernandia nymphaeifolia (C. Presl) Kubitzki Source classification Lignans Phenylpropanoids Plants	Bacterial
(+)-Epieudesmin is an antineoplastic agent. (+)-Epieudesmin has marginal cancer cell line inhibitory activities. (+)-Epieudesmin inhibits the growth of *Gram-negative* pathogen .

HY-114938

Fumaramidmycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Fumaramidmycin is an antibiotic found in Streptomyces kurssanovii NR-7GG1. Fumaramidmycin shows an antimicrobial activity against both *Gram-positive* and Gram-negative bacteria .

HY-116271

Sperabillin C	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus .

HY-113678

Colistin Polymyxin E	Microorganisms Source classification	Antibiotic Bacterial
Colistin (Polymyxin E) is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli .

HY-N10097

Chamigrenol	Structural Classification Cupressaceae Terpenoids Sesquiterpenes Source classification Plants Thujopsis dolabrata (Thunberg ex L. f.) Sieb. et Zucc.	Na+/K+ ATPase Bacterial
Chamigrenol is a Na ⁺/K ⁺-ATPase inhibitor with an IC₅₀ value of 15.9 μg/mL. Chamigrenol shows strong inhibitory activities against *Gram-positive* and Gram-negative bacteria except Escherichia coli, with MIC values of 50 µg/mL .

HY-N1240

Sissotrin Biochanin A 7-glucoside; Sissonin	Structural Classification Flavonoids Leguminosae Source classification Sophora japonica (L.) Schott Plants Isoflavones	Bacterial
Sissotrin (Biochanin A 7-glucoside) has potent antimicrobial and antioxidant activities. Sissotrin is active against the yeasts and Gram-positive and Gram-negative bacteria with MICs of 32-256 μg/mL .

HY-P5708

Adenoregulin Dermaseptin b2	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Antibiotic Fungal Bacterial
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

HY-113801

N-(3-Oxooctanoyl)-DL-homoserine lactone (Rac)-3-oxo-C8-HSL	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots .

HY-111190

Thiotropocin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Thiotropocin is a tropothione Antibiotic with antibacterial activities against Gram-positive and Gram-negative bacteria, some phytopathogens and mycoplasma. Thiotropocin causes morphological changes of Proteus mirabilis and Escherichia coli .

HY-W012595A

trans-Benzylideneacetone trans-Benzalacetone	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Inflammation/Immunology Disease Research Fields	Phospholipase
trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant .

HY-A0089

Colistin sulfate 15+ Cited Publications Polymyxin E sulfate	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Autophagy Antibiotic
Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.

HY-125496

A201A	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation .

HY-117108

Nocardicin A	Structural Classification Microorganisms Antibiotics Source classification Beta-lactam Antibiotics	Antibiotic Bacterial
Nocardicin A is a beta-lactam antibiotic with selective antibacterial activity. Nocardicin A has moderate antibacterial activity against a broad spectrum of Gram-negative bacteria including Proteus and Pseudomonas; it has no inhibitory effect on Staphylococcus, Mycobacterium, fungi, and yeast .

HY-B1174R

Bekanamycin (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Antibiotic Bacterial
Bekanamycin (Standard) is the analytical standard of Bekanamycin. This product is intended for research and analytical applications. Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-N10271

SCH 38519	Infection Quinones Monophenols Microorganisms Classification of Application Fields Anthraquinones Source classification Phenols Disease Research Fields	Bacterial
SCH 38519 is a platelet aggregation inhibitor. SCH 38519 inhibits thrombin-induced aggregation of human platelets with an IC₅₀ of 68 μg/mL. SCH 38519 is also active against Gram-positive and Gram-negative bacteria .

HY-133683

N-(3-Oxotetradecanoyl)-DL-homoserine lactone 3-Oxo-C14-AHL	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Bacterial
N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule .

HY-A0089R

Colistin (sulfate) (Standard)	Structural Classification Microorganisms Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Other Antibiotics	Bacterial Autophagy Antibiotic
Colistin (sulfate) (Standard) is the analytical standard of Colistin (sulfate). This product is intended for research and analytical applications. Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.

HY-B1802A

Tosufloxacin tosylate hydrate 2 Publications Verification A-61827 tosylate hydrate; T-3262	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-N3138

Ombuoside	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Cucurbitaceae Phenols Polyphenols Plants Gynostemma pentaphyllum (Thunb.) Makino Disease Research Fields	Bacterial
Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.Ombuoside has antimicrobial activity against several strains of gram-positive and gram-negative bacteria and the yeast Candida albicans . Ombuoside has antioxidant effects by scavenging free radicals and ROS .

HY-N7505

Norchelerythrine	Infection Alkaloids Classification of Application Fields Source classification Macleaya cordata (Willd.) R. Br. Plants Isoquinoline Alkaloids Disease Research Fields Papaveraceae	Bacterial
Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL .

HY-N13883

Aerocavin	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Aerocavin is an antibiotic that is active against both Gram-positive and Gram-negative bacteria in vitro .

HY-B1908

Midecamycin 2 Publications Verification SF-837; Antibiotic SF-837	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.

HY-B0275

Oxytetracycline 5 Publications Verification	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Endogenous metabolite Other Antibiotics Plant agriculture research Infection Monophenols Microorganisms Antibiotics Resistance Selection Animal Husbandry Phenols Disease Research Fields	Bacterial HSV Endogenous Metabolite Antibiotic
Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

HY-B0275A

Oxytetracycline hydrochloride 5 Publications Verification	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Endogenous metabolite Other Antibiotics Infection Monophenols Microorganisms Antibiotics Phenols Disease Research Fields	Bacterial HSV Antibiotic Endogenous Metabolite
Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity .

HY-N7112

Leucomycin Kitasamycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses .

HY-B0474

Tetracycline hydrochloride 35+ Cited Publications	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Plant agriculture research Infection Monophenols Microorganisms Antibiotics Resistance Selection Animal Husbandry Phenols Mammalian Cell Culture Disease Research Fields	Bacterial Antibiotic
Tetracycline (hydrochloride) is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.

HY-N3296

Meridinol (-)-Meridinol	Zanthoxylum bungeanum Maxim. Structural Classification Source classification Lignans Rutaceae Phenylpropanoids Plants	Bacterial Fungal
Meridinol ((-)-Meridinol) shows antimicrobial activity against a wide range of gram-positive and gram-negative bacteria and fungi.

HY-B0275C

Oxytetracycline calcium	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Endogenous metabolite Disease Research Fields	Bacterial HSV Antibiotic Endogenous Metabolite
Oxytetracycline calcium is an antibiotic belonging to the tetracycline class. Oxytetracycline calcium potently inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline calcium is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline calcium also possesses anti-HSV-1 activity .

HY-B0275B

Oxytetracycline dihydrate 5 Publications Verification	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Endogenous metabolite Other Antibiotics Infection Monophenols Microorganisms Antibiotics Phenols Disease Research Fields	Bacterial HSV Antibiotic Endogenous Metabolite
Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. Oxytetracycline dihydrate potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1 activity .

HY-N0195

Azomycin 2-Nitroimidazole	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.

HY-121144

Cefazedone Refosporen	Infection Structural Classification Animals Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Cefazedone (Refosporen), a first-generation cephalosporin, is a time-dependent antibiotic with activity against Gram-positive and Gram-negative bacteria .

HY-129673

Sarubicin A U-58431	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Sarubicin A (U-58431) is an antibiotic that inhibits Gram-positive and Gram-negative bacteria and has antitumor activity .

HY-129493

Lateropyrone	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Antibiotic Endogenous Metabolite
Lateropyrone is a type of pyranone antibiotic that can inhibit Gram-negative bacteria, and it's a secondary metabolite produced by the oat fungal pathogen .

HY-N13884

Amythiamicin D	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Amythiamicin D is a thiopeptide antibiotic that inhibits the growth of many Gram-positive bacteria, but not Gram-negative bacteria such as E.coli .

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-B0438

Spectinomycin dihydrochloride 3 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Resistance Selection Source classification Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an K_i value of 7.2 mM ^- .

HY-B0275AR

Oxytetracycline (hydrochloride) (Standard)	Structural Classification Monophenols Microorganisms Antibiotics Source classification Phenols Antibacterial Disease Research Endogenous metabolite Other Antibiotics	Bacterial HSV Antibiotic Endogenous Metabolite
Oxytetracycline (hydrochloride) (Standard) is the analytical standard of Oxytetracycline (hydrochloride). This product is intended for research and analytical applications. Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity .

HY-B0275R

Oxytetracycline (Standard)	Structural Classification Source classification Antibacterial Disease Research Endogenous metabolite Other Antibiotics Plant agriculture research Monophenols Microorganisms Antibiotics Resistance Selection Animal Husbandry Phenols	Bacterial HSV Endogenous Metabolite Antibiotic
Oxytetracycline (Standard) is the analytical standard of Oxytetracycline. This product is intended for research and analytical applications. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

HY-N12096

Galbinic acid α-Acetylsalazinic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Polyphenols	Bacterial
Galbinic acid (α-Acetylsalazinic acid), a lichen acid, shows antibacterial activities against the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus (MICs=62.5, 62.5, 250 μg/ml, respectively). Galbinic acid inhibits the Gram-negative bacterium E. coli (MIC=125 μg/ml) .

HY-Y0264

4-Hydroxybenzoic acid	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Monophenols Microorganisms Leguminosae Ketones, Aldehydes, Acids Phenols Glycyrrhiza uralensis Fisch. Disease Research Fields	Endogenous Metabolite Bacterial
4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC₅₀ of 160 μg/mL.

HY-13212

(Z)-2-Decenoic acid cis-2-Decenoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Cancer	Bacterial
(Z)-2-decenoic acid (cis-2-Decenoic acid) is an unsaturated fatty acid produced by Pseudomonas aeruginosa. (Z)-2-decenoic acid induces a dispersion response in biofilms formed by a range of gram-negative bacteria, including P. aeruginosa, and by gram-positive bacteria. (Z)-2-decenoic acid inhibits biofilm development .

HY-120733

Calpinactam FKI-4905	Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Inflammation/Immunology	Bacterial Endogenous Metabolite
Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively .

HY-P0270

Magainin 2 Magainin II	Infection Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial Antibiotic Fungal
Magainin 2 (Magainin II) is an?antimicrobial?peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-B0132

Norfloxacin 3 Publications Verification MK-0366	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Bacterial Endogenous Metabolite Antibiotic
Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

HY-B0275BR

Oxytetracycline (dihydrate) (Standard)	Structural Classification Monophenols Microorganisms Antibiotics Source classification Phenols Antibacterial Disease Research Endogenous metabolite Other Antibiotics	Bacterial HSV Antibiotic Endogenous Metabolite
Oxytetracycline (dihydrate) (Standard) is the analytical standard of Oxytetracycline (dihydrate). This product is intended for research and analytical applications. Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. Oxytetracycline dihydrate potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1 activity .

HY-30219

D-(+)-Phenyllactic acid D-3-Phenyllactic acid	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Bacterial Endogenous Metabolite
D-(+)-Phenyllactic acid is an anti-bacterial agent, excreted by Geotrichum candidum, inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans .

Cat. No.	Product Name	Chemical Structure

HY-B0522S

Ampicillin-d5
Ampicillin-d₅ is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1][2][3].

HY-B0132S

Norfloxacin-d5
Norfloxacin-d₅ is the deuterium labeled Norfloxacin. Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase[1][2].

HY-N0285S

Imperatorin-d6
Imperatorin-d6 (Ammidin-d6) is the deuterium labeled Imperatorin. Imperatorin is a BChE inhibitor and HIV-1 replication inhibitor. Imperatorin shows mild activity against Gram-negative bacteria .

HY-B1085S

Cinoxacin-d5

Cinoxacin-d₅ is the deuterium-labeled Cinoxacin (HY-B1085) . Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis .

HY-B1190S

Cefadroxil-d4 hydrate
Cefadroxil-d₄ (hydrate) is the deuterium labeled Cefadroxil. Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.

HY-A0107S

Tetracycline-d6
Tetracycline-d₆ is the deuterium labeled Tetracycline. Tetracycline is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.

HY-B1781S

Sulfachloropyridazine-13C6
Sulfachloropyridazine- ¹³C₆ is the ¹³C₆ labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.

HY-136382S

Sulfachloropyridazine-d4
Sulfachloropyridazine-d₄ is the deuterium labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria[1].

HY-A0269S

Mecillinam-d12
Mecillinam-d₁₂ is deuterium labeled Mecillinam. Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms[1].

HY-B0132S1

Norfloxacin-d8
Norfloxacin-d₈ is the deuterium labeled Norfloxacin. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

HY-19581S

Baquiloprim-d6
Baquiloprim-d₆ is deuterium labeled Baquiloprim. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2].

HY-B1282S

Sulfaquinoxaline-d4
Sulfaquinoxaline-d₄ is the deuterium labeled Sulfaquinoxaline. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections[1][2].

HY-Y0264S1

4-Hydroxybenzoic acid-d4
4-Hydroxybenzoic acid-d₄ is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.

HY-B1256S

Cefuroxime-d3
Cefuroxime-d₃ is deuterium labeled Cefuroxime (sodium). Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria[1].

HY-B0712S

Ceftriaxone-d3 disodium
Ceftriaxone-d₃ (disodium) is the deuterium labeled Ceftriaxone. Ceftriaxone is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics[1][2].

HY-106257S

Ceftolozane-d6 TFA
Ceftolozane-d₆ TFA is a deuterated labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .

HY-Y0264S2

4-Hydroxybenzoic acid-13c
4-Hydroxybenzoic acid- ¹³C is the ¹³C labeled 4-Hydroxybenzoic acid[1]. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL[2].

HY-A0088S

Cefotaxime-d3 sodium
Cefotaxime-d₃ (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria[1][2][3][4][5].

HY-B0126AS

Marbofloxacin-d8 hydrochloride
Marbofloxacin-d₈ (hydrochloride) is deuterium labeled Marbofloxacin (hydrochloride). Marbofloxacin hydrochloride is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin hydrochloride can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma .

HY-B0126S

Marbofloxacin-d8
Marbofloxacin-d₈ is the deuterium labeled Marbofloxacin. Marbofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma[1][2][3].

HY-W654101

Cefotaxime-d3
Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-Y0264S

4-Hydroxybenzoic acid-13C6
4-Hydroxybenzoic acid- ¹³C6 is the ¹³C labeled isotope of 4-Hydroxybenzoic acid- ¹³C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL.

HY-17628S1

Cefiderocol-d6
Cefiderocol-d₆ (S-649266-d₆) is a deuterated labeled Cefiderocol (HY-17628). Cefiderocol is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less .

HY-B0510S

Trimethoprim-d9
Trimethoprim-d₉ is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment[1][2][3].

HY-B0450S1

Ciclopirox-d11 sodium
Ciclopirox-d₁₁ (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

HY-N1500S1

Pulegone-d8
Pulegone-d₈ is deuterated labeled Tetracycline (HY-A0107). Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .

HY-B0450S

Ciclopirox-d11
Ciclopirox-d₁₁ is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

HY-B0479S

Thiamphenicol-d3
Thiamphenicol-d₃ is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria)[1][2].

HY-B0510S2

Trimethoprim-d3
Trimethoprim-d₃is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment[1][2][3].

HY-B1923S

Piperacillin-d5
Piperacillin-d₅ is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins[1].

HY-W011117S

Danofloxacin-d3
Danofloxacin-d₃ is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase[1][2].

HY-W011117S1

Danofloxacin-d3-1
Danofloxacin-d3-1 is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase .

HY-B0113S

Omeprazole-d₃ 1 Publications Verification
Omeprazole-d₃ is deuterium labeled Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].

HY-B1729S1

Phenoxyethanol-d4

Phenoxyethanol-d₄ is the deuterium labeled Phenoxyethanol[1]. Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al[2].

HY-B0398S

Nalidixic Acid-d5

Nalidixic Acid-d₅ is the deuterium labeled Nalidixic acid. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria[1].

HY-B1729S

Phenoxyethanol-d2

Phenoxyethanol-d₂ is the deuterium labeled Phenoxyethanol[1]. Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al[2].

HY-17395S

Terbinafine-d3 hydrochloride

Terbinafine-d₃ (hydrochloride) is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-17395AS

Terbinafine-d7
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-B0275S

Oxytetracycline-d6
Oxytetracycline-d₆ is deuterium labeled Oxytetracycline. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

HY-B1002S

Oxolinic acid-d5
Oxolinic acid-d₅ is the deuterium labeled Oxolinic acid. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice[1][2][3].

HY-130187S

Sapienic acid-d19

Sapienic acid-d19 is a deuterated labeled Sapienic acid . Sapienic acid is a fatty acid commonly found on the skin and in mucosa. Sapienic acid has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively .

HY-B0330BS1

Levofloxacin-d3 hydrochloride

Levofloxacin-d₃ ((-)-Ofloxacin-d₃) hydrochlorideis deuterium labeled Levofloxacin (hydrochloride). Levofloxacin ((-)-Ofloxacin) hydrochloride is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrochloride can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrochloride shows anti-orthopoxvirus activity .

HY-B0395S

Sitafloxacin-d4

Sitafloxacin-d₄ (DU6859a-d₄) is deuterium labeled Sitafloxacin. Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .

HY-B0510S3

Trimethoprim-13C3

Trimethoprim- ¹³C₃ is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .

HY-W653936

Cephalexin-d5 hydrate

Cephalexin-d₅ (hydrate) is deuterium labeled Cephalexin (monohydrate). Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-B0136S

Cefdinir-13C,15N2

Cefdinir- ¹³C, ¹⁵N₂ (FK-482- ¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-B0479S1

Thiamphenicol-d3-1

Thiamphenicol-d₃-1 (Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-N6948S

Linalyl acetate-d6

Linalyl acetate-d₆ is deuterated labeled Omeprazole (HY-B0113). Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a K_i of 2 to 6 μM . Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria .Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) .

HY-B0113S1

Omeprazole-d3-1

Omeprazole-d₃-1 is the deuterium labeled Omeprazole. Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[3].

HY-B1118S2

Secnidazole-d4

Secnidazole-d₄ is the deuterium labeled Secnidazole[1]. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis[1][2][3].

Cat. No.	Product Name		Classification

HY-130379

Propargyl-PEG8-acid		ADC Synthesis PROTAC Synthesis Alkynes
Propargyl-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria . Propargyl-PEG8-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-105674

Azidamfenicol		Azide
Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic. Azidamfenicol inhibits ribosomal peptidyltransferase (K_i=22 μM) . Azidamfenicol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-W089856

Chlorobutanol hemihydrate		Preservatives
Chlorobutanol hemihydrate is an antimicrobial agent with oral activity, also possessing preservative effects. Chlorobutanol hemihydrate exhibits resistance to a variety of Gram-positive and Gram-negative bacteria, as well as several fungal spores and fungi, and is widely used in the food and cosmetics industries .

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