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dC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) ADC Cytotoxin (10) Adrenergic Receptor (4) Akt (4) Amyloid-β (1) Anaplastic lymphoma kinase (ALK) (2) Androgen Receptor (9) ANGPTL (1) Antibiotic (7) Apoptosis (33) Atg8/LC3 (1) ATM/ATR (1) Aurora Kinase (1) Autophagy (10) AUTOTACs (3) Bacterial (4) Bcl-2 Family (4) BCL6 (1) Bcr-Abl (12) Btk (10) Casein Kinase (2) Caspase (1) CDK (13) Checkpoint Kinase (Chk) (1) Cytochrome P450 (1) Dengue virus (2) Deubiquitinase (3) Discoidin Domain Receptor (1) DNA Alkylator/Crosslinker (2) DNA Methyltransferase (4) DNA/RNA Synthesis (20) E3 Ligase Ligand-Linker Conjugates (4) Early 2 Factor (E2F) (1) EGFR (13) Endogenous Metabolite (3) Enterovirus (1) Epigenetic Reader Domain (54) ERK (2) Estrogen Receptor/ERR (13) FAK (8) Ferroptosis (5) FGFR (4) FKBP (1) FLT3 (4) Fluorescent Dye (3) Free Fatty Acid Receptor (1) G-quadruplex (1) Glucosidase (1) Glutathione Peroxidase (3) GSK-3 (1) HBV (1) HCV (1) HDAC (6) Histone Acetyltransferase (4) Histone Methyltransferase (7) HSP (2) IAP (1) IFNAR (1) IKK (2) IKZF Family (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Integrin (1) Interleukin Related (1) IRAK (14) Itk (1) JAK (2) Ligands for E3 Ligase (7) Ligands for Target Protein for PROTAC (3) Liposome (8) LRRK2 (1) mAChR (2) MAP4K (4) MDM-2/p53 (2) MEK (1) Methylenetetrahydrofolate Dehydrogenase (MTHFD) (1) MicroRNA (2) Molecular Glues (13) NF-κB (5) NOD-like Receptor (NLR) (1) Nucleoside Antimetabolite/Analog (17) Oxytocin Receptor (1) p38 MAPK (5) p62 (1) Parasite (2) PARP (1) PCSK9 (1) PD-1/PD-L1 (1) Phosphatase (1) Phosphodiesterase (PDE) (2) PIKfyve (2) PIN1 (1) PKA (1) Polo-like Kinase (PLK) (1) PPAR (1) Prostaglandin Receptor (1) PROTAC Linkers (3) PROTAC-Linker Conjugates for PAC (3) PROTACs (206) Raf (2) RAR/RXR (1) Ras (7) Reactive Oxygen Species (3) ROS Kinase (1) SARS-CoV (2) SGK (1) Sirtuin (1) Small Interfering RNA (siRNA) (2) SNIPERs (11) Sodium Channel (1) Src (2) STAT (5) STING (5) Target Protein Ligand-Linker Conjugates (1) Tim3 (1) TNF Receptor (1) Toll-like Receptor (TLR) (4) Topoisomerase (2) Trk Receptor (1) Vasopressin Receptor (1) VEGFR (1) Virus Protease (1) Wee1 (1) YAP (2) α-synuclein (1)
By Research Areas:	Cancer (347) Cardiovascular Disease (6) Endocrinology (2) Infection (25) Inflammation/Immunology (47) Metabolic Disease (13) Neurological Disease (7)
Click Chemistry:	PROTAC Synthesis (1) Azide (16) Alkynes (3)
Oligonucleotides:	Nucleosides and their Analogs (5) Nucleoside Phosphoramidites (15) Aptamers (1) Pre-designed siRNA Sets (2) CpG ODNs (2) Cationic Lipids (5) Phospholipids (1) Antisense Oligonucleotides (2) Cholesterol (2) siRNAs (2)

439

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

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Recombinant Proteins

Isotope-Labeled Compounds

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-137131

DC-Chol hydrochloride dC-Cholesterol hydrochloride	Amyloid-β Liposome	Neurological Disease
DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner .

HY-12746

DC-05 1 Publications Verification	DNA Methyltransferase	Cancer
DC-05 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC₅₀ and a K_d of 10.3 μM and 1.09 μM, respectively.

HY-12747

DC_517 2 Publications Verification	DNA Methyltransferase	Cancer
DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC₅₀ and a K_d of 1.7 μM and 0.91 μM, respectively.

HY-129379

DC0-NH2	ADC Cytotoxin	Cancer
DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer agents (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component .

HY-107767

Antibiotic DC 81 dC 81	Antibiotic Apoptosis DNA/RNA Synthesis	Cancer
Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct .

HY-126788

Antibiotic DC 102 dC 102	Antibiotic	Infection Metabolic Disease
Antibiotic DC 102 is a new glycosidic pyrrole(1,4)benzodiazepine antibiotic with a MIC value of 42 μg/mL target Bacillus subtilis No. 10707. Antibiotic DC 102 has an LD₅₀ value of 1.5mg/mL(i.p) in mouse .

HY-112901

DC41	ADC Cytotoxin	Cancer
DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer .

HY-163794

DC371739	ANGPTL PCSK9	Metabolic Disease
DC371739 is a potent and orally activity PCSK9 inhibitor. DC371739 decreases the mRNA expression of PCSK9 and ANGPTL3. DC371739 decreases the protein expression of PCSK9 and increases the protein expression of LDLR. DC371739 has the potential for the research of hyperlipidemia .

HY-130596

DC-86-M	Antibiotic Bacterial	Infection Cancer
DC-86-M is an antibiotic, which can be isolated from Streptomyces luteogriseus. DC-86-M exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Vibrio anguillarum, and Proteus vulgaris, with MIC <1 μg/mL. DC-86-M exhibits antitumor activity against mouse sarcoma 180 with LD₅₀ of 25 mg/kg .

HY-135125

DC4	ADC Cytotoxin	Cancer
DC4, an ADC cytotoxin, can be used in the synthesis of antibody-drug conjugate (ADC). DC4 can be used for the targeted treatment of cancer .

HY-W800782

DC-6-14	Liposome	Others
DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .

HY-126621

DC-TEADin02	YAP	Cancer
DC-TEADin02 is a potent TEAD autopalmitoylation inhibitor. DC-TEADin02 has TEAD autopalmitoylation inhibitory with the IC₅₀ value of 197 nM. DC-TEADin02 can be used for the research of development, regeneration and tissue homeostasis .

HY-112899

DC1	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

HY-135124

DC44SMe	ADC Cytotoxin	Cancer
DC44SMe, a phosphate proagent of cytotoxic DNA alkylator DC44, can be used in the synthesis of antibody-drug conjugate (ADC). DC44SMe exhibits IC₅₀s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer .

HY-135123

DC4SMe	ADC Cytotoxin	Cancer
DC4SMe, a phosphate proagent of cytotoxic DNA alkylator DC4, can be used in the synthesis of antibody-drug conjugate (ADC). DC4SMe exhibits IC₅₀s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer .

HY-112898

DC1SMe	ADC Cytotoxin	Cancer
DC1Sme, a DC1 derivative, exhibits IC₅₀ values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

HY-154919

DC-Y13-27 2 Publications Verification	Others	Cancer
DC-Y13-27, a derivative of DC-Y13, is a YTHDF2 inhibitor (K_D: 37.9 μM). DC-Y13-27 enhances tumor responses to radiotherapy and immunotherapy .

HY-101906

DC260126 3 Publications Verification	Free Fatty Acid Receptor Apoptosis	Metabolic Disease
DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca ²⁺ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC₅₀: 6.28, 5.96, 7.07, 4.58 μM, respectively) . DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis .

HY-112900

DC41SMe	ADC Cytotoxin	Cancer
DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC₅₀s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer .

HY-P5162

Dc1a	Sodium Channel	Inflammation/Immunology
Dc1a potently promotes opening of the German cockroach Na_v channel (BgNa_v1). Dc1a is a toxin can be isolated from the desert bush spider Diguetia canities .

HY-121093

DC-S239	Histone Methyltransferase	Cancer
DC-S239 is a selective histone methyltransferase SET7 inhibitor with an IC₅₀ value of 4.59 μM. DC-S239 also displays selectivity for DNMT1, DOT1L, EZH2, NSD1, SETD8 and G9a. DC-S239 has anticancer activity .

HY-D1190

DC271	RAR/RXR	Inflammation/Immunology
DC271 is a RAR agonist that can be considered a retinoid, eliciting cellular responses consistent with the endogenous retinoid ATRA and the synthetic retinoid EC23. DC271 binds to retinoid protein machinery, including CRABPII, to translocate the endogenous retinoid ATRA into the nucleus .

HY-150505

DC-U4106	Deubiquitinase Apoptosis	Cancer
DC-U4106 is a USP8 targeting inhibitor with the K_dvalue of 4.7 μM and the IC₅₀ value of 1.2 μM. DC-U4106 can target the ubiquitin pathway and facilitate the degradation of Erα. DC-U4106 inhibits tumor growth with minimal toxicity and has the potential for the research of breast cancer .

HY-160477

DC-SX029	PIKfyve NF-κB IKK	Inflammation/Immunology
DC-SX029 is a potent SNX10 protein-protein interaction (PPI) inhibitor with an estimated K_D constant of ~0.935 μM by surface plasmon resonance (SPR). DC-SX029 blocks the SNX10-PIKfyve interaction, thereby decreased the TBK1/c-Rel signaling activation. DC-SX029 does not affect the protein level of SNX10. DC-SX029 has the potential for inflammatory bowel disease (IBD) research .

HY-141703

DC-BPi-11	Epigenetic Reader Domain	Cancer
DC-BPi-11 is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC₅₀ value of 698 nM. DC-BPi-11 shows remarkable inhibition against leukemia cell proliferation .

HY-141703A

DC-BPi-11 hydrochloride	Epigenetic Reader Domain	Cancer
DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC₅₀ value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation .

HY-120937

DC4 Crosslinker	Others	Others
DC4 Crosslinker is a stable crosslinking reagent with improved activity and solubility. DC4 Crosslinker is labile cleavable with collision-induced dissociation (CID), that will be fragmented into four rearrange products containing mobilized protons .

HY-147868

DC-CPin711	Epigenetic Reader Domain Apoptosis	Cancer
DC-CPin711 is a potent and selective inhibitor of CREB-binding protein (CBP) bromodomain with an IC₅₀ of 0.0626 μM. DC-CPin711 arrests cell cycle at G1 phase and induces apoptosis .

HY-123517

DC07090 dihydrochloride	Enterovirus	Infection
DC07090 dihydrochloride is a low toxicity, potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC₅₀ and a K_i value for 21.72 μM and 23.29 μM. DC07090 dihydrochloride could also inhibit coxsackievirus A16 (CVA16) replication with an EC₅₀ value of 27.76 μM .

HY-119975

Carazostatin dC118	Reactive Oxygen Species	Cancer
Carazostatin (DC118), an antioxidant, can be isolated from Streptomycs chromofuscus. Carazostatin (DC118) exhibits strong inhibitory activity against free radical-induced lipid peroxidation and shows stronger antioxidant activity in liposomal membranes than α-tocopherol (VE) .

HY-135122

DC10SMe	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
DC10SMe is a DNA alkylator, can be used in the synthesis of antibody-drug conjugate (ADC). DC10SMe exhibits IC₅₀s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/s cancer cells, respectively .

HY-160657

DC-TEADin04	Others	Others
DC-TEADin04 has weak inhibitory activity against TEAD4 palmitoylation .

HY-111621

DC661 4 Publications Verification	Autophagy Apoptosis	Cancer
DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity .

HY-139890

DC-Srci-6649	Src	Others
DC-Srci-6649 is a c-Src kinase inhibitor that inhibits the phosphorylation and locks c-Src in the inactive state.

HY-100855

DC_C66	Histone Methyltransferase	Cancer
DC_C66 is a cell-permeable, selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC₅₀ of 1.8 μM. DC_C66 has a good selectivity for CARM1 against PRMT1 (IC₅₀=21 μM), PRMT6 (IC₅₀= 47μM), and PRMT5 .

HY-147869

DC-CPin7	Epigenetic Reader Domain	Cancer
DC-CPin7 is a potent inhibitor of CREB-binding protein (CBP) bromodomain with an IC₅₀ of 2.5 μM .

HY-150211

DC-BPi-03	Epigenetic Reader Domain	Cancer
DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC₅₀ of 698.3 nM and a K_d of 2.81 μM .

HY-141882

DC-LC3in-D5	Atg8/LC3 Autophagy	Infection Inflammation/Immunology Cancer
DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC₅₀ of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy .

HY-129292

Quinocarcin Quinocarmycin; dC-52; KW2152 free base	Antibiotic Bacterial	Infection Cancer
Quinocarcin (DC-52) is a potent antitumor antibiotic. Quinocarcin inhibits Bacillus subtilis DNA, RNA and protein syntheses .

HY-107636

DC_AC50 2 Publications Verification	Apoptosis	Cancer
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance .

HY-P99892

Serclutamab PR-1594407; dC-1630423	EGFR	Others
Serclutamab is a humanized chimeric antibody targeting EGFR IgG1-κ. Mainly expressed by CHO (Chinese Hamster Ovary) cells .

HY-149664

3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol dC-Chol	Liposome	Cancer
3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .

HY-151509

A2-Iso5-2DC18	Others	Cancer
A2-Iso5-2DC18 is a dihydroimidazole-linked lipid, served as potent mRNA delivery vehicle. A2-Iso5-2DC18 can be used for antitumor research, including B16F10 melanoma. .

HY-153469

Benzyl DC-81	ADC Cytotoxin	Cancer
Benzyl DC-81 (Compound 6a) is an anticancer agent with antiproliferative activity against A375 and MCF-7 cells .

HY-116893

Diethyl bipy55'DC	Others	Cancer
Diethyl bipy55'DC is an inhibitor of collagen proline 4-hydroxylases (CP4Hs) with antifibrotic and anti-metastatic activities. Diethyl bipy55'DC can inhibit CP4H activity in cultured cells at concentrations that do not cause iron deficiency .

HY-45491

Dmt-2'-f-dc(ac) amidite 2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite	Nucleoside Antimetabolite/Analog	Others
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .

HY-138584

IBU-DC Phosphoramidite	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Infection Cancer
IBU-DC Phosphoramidite is used for synthesis of oligonucleotides .

HY-151510

A2-Iso5-4DC19	Liposome	Others
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .

HY-151512

A12-Iso5-4DC19	Liposome	Inflammation/Immunology Cancer
A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .

HY-W008849

DMT-dC(bz) Phosphoramidite	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Others
DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0119

Naringin Dihydrochalcone 1 Publications Verification Naringin dC	Structural Classification Classification of Application Fields Source classification Plants Dihydrochalcones Sweeteners Food Research Flavonoids other families Phenols Polyphenols Disease Research Fields Cancer	NF-κB
Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.

HY-N0154

Neohesperidin dihydrochalcone 1 Publications Verification Neohesperidin dC; NHdC	Structural Classification Classification of Application Fields Source classification Plants Dihydrochalcones Sweeteners Food Research Flavonoids other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species
Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener.

HY-N2120

Dichotomitin	Flavonoids Iridaceae Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Isoflavones	Others
Dichotomitin is an isoflavonoid isolated from the rhizomes of Belamcanda chinensis (L.) DC .

HY-N10886

Eupatolitin Eupatoletin	Structural Classification Flavonols Flavonoids Source classification Centaurea aspera stenophylla Plants Umbelliferae	Others
Eupatoletin is a flavonol compound isolated from Eupatorium ligustrinum D.C. .

HY-N8922

Platycodin A	Triterpenes Classification of Application Fields Terpenoids Source classification Other Diseases Campanulaceae Plants Disease Research Fields	Others
Platycodin A is monoacetylated saponin compound isolated fromhe roots of Platycodon grandiflorum A. DC. .

HY-126788

Antibiotic DC 102 dC 102	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic
Antibiotic DC 102 is a new glycosidic pyrrole(1,4)benzodiazepine antibiotic with a MIC value of 42 μg/mL target Bacillus subtilis No. 10707. Antibiotic DC 102 has an LD₅₀ value of 1.5mg/mL(i.p) in mouse .

HY-130596

DC-86-M	Structural Classification Microorganisms Antibiotics Source classification Disease Research Anticancer	Antibiotic Bacterial
DC-86-M is an antibiotic, which can be isolated from Streptomyces luteogriseus. DC-86-M exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Vibrio anguillarum, and Proteus vulgaris, with MIC <1 μg/mL. DC-86-M exhibits antitumor activity against mouse sarcoma 180 with LD₅₀ of 25 mg/kg .

HY-117818

Sapurimycin Antibiotic dC 116	Structural Classification Microorganisms Antibiotics Source classification Disease Research Anticancer	Antibiotic
Sapurimycin is an antitumor antibiotic isolated from Streptomyces DO-116 and belongs to the capramycin family. Sapurimycin exhibits potent activity against Gram-positive bacteria and exhibits significant antitumor effects against leukemia P388 and sarcoma 180 in mouse models. In vitro studies have shown that Sapurimycin can induce single-strand breaks in supercoiled plasmid DNA .

HY-N11032

Menisporphine	Structural Classification Alkaloids Source classification Plants Isoquinoline Alkaloids Menispermaceae Menispermum dauricum	Others
Menisporphine is an alkaloid that can be found in Menisperum dauricum DC .

HY-N11029

Dauriporphine	Structural Classification Alkaloids Source classification Plants Isoquinoline Alkaloids Menispermaceae Menispermum dauricum	Others
Dauriporphine, an alkaloid, can be isolated from the vines of Menispermum dauricum DC .

HY-N1303

Shoreic acid Shoric acid	Structural Classification Ketones, Aldehydes, Acids Source classification Cabralea eichleriana DC. Plants Meliaceae	Others
Shoreic acid (compound 8a) is a dammarane skeleton compound isolated from Cabralea eichleriana DC .

HY-N3017

Artemitin	Flavonols Structural Classification Monophenols Flavonoids other families Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Antibiotic
Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity .

HY-N3309

Mearnsitrin	Myrcia multiflora (Lam.) DC. Structural Classification Flavonols Flavonoids Source classification Phenols Polyphenols Myrtaceae Plants	Others
Mearnsitrin (compound 8) is a flavonol that can be isolated from methanolic extract Myrcia multiflora DC .

HY-N12499

Eupalitin	Structural Classification Flavonols Flavonoids Melilotus albus Desr. Source classification Plants Compositae	Others
Eupalitin, flavonol, is an active natural product. Eupalitin can be isolated from Eupatorium ligustrinum D.C .

HY-N4258

Panasenoside	Panax ginseng C. A. Meyer Flavonols Classification of Application Fields Source classification Metabolic Disease Plants Lilium pumilum DC. Flavonoids Liliaceae Phenols Polyphenols Disease Research Fields Araliaceae	Glucosidase
Panasenoside is a flavonoid isolated from Lilium pumilum DC. Panasenoside exhibits α-glucosidase inhibitory activity .

HY-N3741

Didrovaltrate Didrovaltratum	Natural Products Classification of Application Fields Source classification Valeriana officinalis Linn. Plants Valerianaceae Disease Research Fields Cancer	Others
Didrovaltrate (Didrovaltratum) can be isolated from the roots of Valeriana wallichii D.C. Didrovaltrate is an antitumor agent with cytotoxicity .

HY-N8379

Morolic acid	Triterpenes Structural Classification Phoradendron brachystachyum (DC.) Nutt. Ketones, Aldehydes, Acids Terpenoids Source classification Plants Santalaceae	Others
Morolic acid (compound 6) can be isolated from Phoradendron brachystachyum DC Nutt. Morolic acid has antiretroviral activity .

HY-N2358

Blumeatin	Flavonoids Classification of Application Fields Flavonones Source classification Phenols Polyphenols Plants Acacia confusa Merr. Compositae Disease Research Fields Inflammation/Immunology	Others
Blumeatin, isolated from Blumea balsamifera DC, could protect liver against injury induced by CCl4 and thioacetamide (TAA) .

HY-N3017R

Artemitin (Standard)	Flavonols Structural Classification Monophenols Flavonoids other families Source classification Phenols Plants	Antibiotic
Artemitin (Standard) is the analytical standard of Artemitin. This product is intended for research and analytical applications. Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity .

HY-N4157

Isopteropodine	Uncaria rhynchophylla (Miq.) Miq. ex Havil. Iridoids Terpenoids Source classification Rubiaceae Plants	mAChR 5-HT Receptor
Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors .

HY-113042

Prostaglandin B2	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw .

HY-N7665

Prosaikogenin G	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Metabolic Disease Umbelliferae Plants Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray	Others
Prosaikogenin G, isolated from the roots of Bupleurum chinensis DC., exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney . Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract .

HY-N4157R

Isopteropodine (Standard)	Uncaria rhynchophylla (Miq.) Miq. ex Havil. Structural Classification Iridoids Terpenoids Source classification Rubiaceae Plants	mAChR 5-HT Receptor
Isopteropodine (Standard) is the analytical standard of Isopteropodine. This product is intended for research and analytical applications. Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors .

HY-130801

5-Hydroxy-2'-deoxyuridine 5-OHdU	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase .

HY-P99742

Mitazalimab AdC-1013; JNJ-64457107	Classification of Application Fields Disease Research Fields Cancer	TNF Receptor
Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment .

HY-N4215

11(α)-Methoxysaikosaponin F	Triterpenes Classification of Application Fields Terpenoids Source classification Plants Umbelliferae Disease Research Fields Inflammation/Immunology Carphephorus corymbosus (Nutt.) Torr. & A.Gray	Others
11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC₅₀ of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity .

HY-N0498

Nitidine chloride 3 Publications Verification	Alkaloids Structural Classification Classification of Application Fields Source classification Rutaceae Zanthoxylum nitidum (Roxb.) DC. Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields	Parasite Apoptosis STAT Topoisomerase ERK FAK p38 MAPK NF-κB
Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway .

HY-P2358

PSMα3	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Toll-like Receptor (TLR)
PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA) .

HY-N0498R

Nitidine chloride (Standard)	Alkaloids Structural Classification Source classification Rutaceae Zanthoxylum nitidum (Roxb.) DC. Plants Isoquinoline Alkaloids	Parasite Apoptosis STAT Topoisomerase ERK FAK p38 MAPK NF-κB
Nitidine (chloride) (Standard) is the analytical standard of Nitidine (chloride). This product is intended for research and analytical applications. Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway .

HY-N11507

Tibesaikosaponin V TKV	Triterpenes Structural Classification Terpenoids Source classification Plants Umbelliferae Sideritis congesta P.H.Davis & Hub.-Mor.	PPAR
Tibesaikosaponin V (TKV) is a triterpene diglycoside, which can be isolated from the methanol extract of the roots of Bupleurum chinense DC.. Tibesaikosaponin V inhibits lipid accumulation and triacylglycerol content occurred without cytotoxicity to adipocytes. Tibesaikosaponin V suppresses the mRNA expression of nuclear transcription factors, such as peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα). Tibesaikosaponin V inhibits 3T3-L1 preadipocyte differentiation. Tibesaikosaponin V can be used fro research of obesity and its associated metabolic disorders .

HY-N10922

(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone	Structural Classification Terpenoids Source classification Celastraceae Diterpenoids Celastrus Plants	Others
(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3), a Palmitate, can be isolated from the root tissue of Salvia miltiorrhiza. (3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3) shows anti-cancer activity against human cancer cell lines with DC₅₀s of 25.5 μg/mL (HeLa), 37.5 μg/mL (HepG2), 30.2 μg/mL (OVCAR-3), respectively .

Cat. No.	Product Name	Chemical Structure

HY-W008849S

DMT-dC(bz) Phosphoramidite-13C9,15N3
DMT-dC(bz) Phosphoramidite- ¹³C₉, ¹⁵N₃ is the ¹³C and ¹⁵N labeled DMT-dC(bz) Phosphoramidite[1]. DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA[2].

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Species:	Human (18) Rhesus Macaque (5) Mouse (4) Rat (2) Cynomolgus (3)
Tag:	His (16) SUMO (1) Tag Free (1) Avi (2) GST (1) Fc (11) Flag (1)
Source:	HEK293 (23) E. coli (6)


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