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Pathways Recommended:	PROTAC Antibody-drug Conjugate/ADC Related

Results for "

linker conjugates for PROTACs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (201) E3 Ligase Ligand-Linker Conjugates (465) Ligands for E3 Ligase (42) Ligands for Target Protein for PROTAC (2) PROTAC Linkers (202) PROTAC-Linker Conjugates for PAC (4) PROTACs (33) Target Protein Ligand-Linker Conjugates (12) 17β-HSD (1) ADC Cytotoxin (1) Androgen Receptor (1) Apoptosis (125) AUTACs (1) Autophagy (164) Bacterial (1) BCL6 (1) Btk (3) c-Myc (1) EGFR (3) Epigenetic Reader Domain (8) Estrogen Receptor/ERR (3) Ferroptosis (1) Glutathione Peroxidase (1) HDAC (1) HIF/HIF Prolyl-Hydroxylase (1) Histone Acetyltransferase (1) Histone Demethylase (1) Mixed Lineage Kinase (2) PARP (1) STAT (1) WDR5 (1) YAP (1) β-catenin (1)
By Research Areas:	Cancer (747) Infection (3) Inflammation/Immunology (19)
Click Chemistry:	ADC Synthesis (54) TCO (2) DBCO (9) PROTAC Synthesis (55) Azide (50) BCN (1) Alkynes (26)

762

Inhibitors & Agonists

Natural
Products

Click Chemistry

Targets Recommended: PROTAC-Linker Conjugates for PAC Drug-Linker Conjugates for ADC Target Protein Ligand-Linker Conjugates ADC Linker E3 Ligase Ligand-Linker Conjugates PROTACs Ligands for Target Protein for PROTAC Antibody-Drug Conjugates (ADCs) PROTAC Linkers Radionuclide-Drug Conjugates (RDCs) Peptide-Drug Conjugate (PDC) Ligands for E3 Ligase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-44148

FAK ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates	Cancer
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation .

HY-132943A

BRD4 ligand-Linker Conjugate 1 TFA	Target Protein Ligand-Linker Conjugates	Cancer
BRD4 ligand-Linker Conjugate 1 TFA (compound 106-1) is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs .

HY-138965A

Pomalidomide-5-C2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-5-C2-NH2 (hydrochloride) is a conjugate of E3 ligase ligand and linker, which can be used for *PROTACs* synthesis .

HY-125906

VHL Ligand-Linker Conjugates 15 E3 Ligase Ligand-linker conjugates 56	E3 Ligase Ligand-Linker Conjugates	Cancer
VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs .

HY-132943

BRD4 ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates	Cancer
BRD4 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs.

HY-139655

cIAP1 Ligand-Linker Conjugates 16	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 16 is an E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.

HY-168245

E3 Ligase Ligand-linker Conjugate 126	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 126 is an E3 Ligase Ligand-linker Conjugate, and can be used for synthesis of PROTACs, such as PROTAC BRM/BRG1 degrader-1 (HY-168242) .

HY-157589

E3 ligase Ligand-Linker Conjugate 31	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 31 is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.

HY-162188

E3 Ligase Ligand-linker Conjugate 15	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 15 is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.

HY-162201

E3 Ligase Ligand-linker Conjugate 48	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 48 is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.

HY-168228

E3 Ligase Ligand-linker Conjugate 123	E3 Ligase Ligand-Linker Conjugates	Others
E3 Ligase Ligand-linker Conjugate 123 is the E3 ligand-linker part of PROTAC SMARCA2/4-degrader-35 (HY-168225). E3 Ligase Ligand-linker Conjugate 123 can be utilized in the synthesis of PROTACs .

HY-128813A

cIAP1 Ligand-Linker Conjugates 15 hydrochloride E3 ligase Ligand-linker conjugates 34 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 15 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 hydrochloride can be used to design SNIPERs .

HY-128815

cIAP1 Ligand-Linker Conjugates 14 E3 ligase Ligand-linker conjugates 36	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 14 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 14 can be used to design SNIPERs .

HY-128820

cIAP1 Ligand-Linker Conjugates 1 E3 ligase Ligand-linker conjugates 41	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 1 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 1 can be used to design SNIPERs .

HY-128819

cIAP1 Ligand-Linker Conjugates 3 E3 ligase Ligand-linker conjugates 40	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 3 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 3 can be used to design SNIPERs .

HY-128812A

cIAP1 Ligand-Linker Conjugates 11 Hydrochloride E3 ligase Ligand-linker conjugates 33 Hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride can be used to design SNIPERs .

HY-128813

cIAP1 Ligand-Linker Conjugates 15 E3 ligase Ligand-linker conjugates 34	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 15 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 can be used to design SNIPERs .

HY-128812

cIAP1 Ligand-Linker Conjugates 11 E3 ligase Ligand-linker conjugates 33	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 11 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 can be used to design SNIPERs .

HY-128817

cIAP1 Ligand-Linker Conjugates 12 E3 ligase Ligand-linker conjugates 38	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 12 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 12 can be used to design SNIPERs .

HY-128818

cIAP1 Ligand-Linker Conjugates 5 E3 ligase Ligand-linker conjugates 39	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 5 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 5 can be used to design SNIPERs .

HY-128816

cIAP1 Ligand-Linker Conjugates 2 E3 ligase Ligand-linker conjugates 37	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 2 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 can be used to design SNIPERs .

HY-128822

cIAP1 Ligand-Linker Conjugates 13 E3 ligase Ligand-linker conjugates 43	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 13 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 13 can be used to design SNIPERs .

HY-128816A

cIAP1 Ligand-Linker Conjugates 2 Hydrochloride E3 ligase Ligand-linker conjugates 37 Hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 Hydrochloride can be used to design SNIPERs .

HY-128826

cIAP1 Ligand-Linker Conjugates 10 E3 ligase Ligand-linker conjugates 47	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 10 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 10 can be used to design SNIPERs .

HY-128824

cIAP1 Ligand-Linker Conjugates 9 E3 ligase Ligand-linker conjugates 45	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 9 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 9 can be used to design SNIPERs .

HY-128825

cIAP1 Ligand-Linker Conjugates 8 E3 ligase Ligand-linker conjugates 46	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 8 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 8 can be used to design SNIPERs .

HY-128823

cIAP1 Ligand-Linker Conjugates 7 E3 ligase Ligand-linker conjugates 44	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 7 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 7 can be used to design SNIPERs .

HY-128821

cIAP1 Ligand-Linker Conjugates 4 E3 ligase Ligand-linker conjugates 42	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs .

HY-128814

cIAP1 Ligand-Linker Conjugates 6 hydrochloride E3 ligase Ligand-linker conjugates 35 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 6 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 6 hydrochloride can be used to design SNIPERs .

HY-130499

ERRα Ligand-Linker Conjugates 1	Target Protein Ligand-Linker Conjugates	Cancer
ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. ERRα Ligand-Linker Conjugates 1 can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1 (HY-128838). PROTAC ERRalpha Degrader-1 is an ERRα degrader .

HY-168233

E3 Ligase Ligand-linker Conjugate 124	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 124 is an E3 ubiquitinase ligand + linker conjugate. E3 Ligase Ligand-linker Conjugate 124 can be used to synthesize PROTAC SMARCA2 degrader-27 (HY-168229) .

HY-168612

E3 Ligase Ligand-linker Conjugate 125	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 125 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 125 can be used to synthesize PROTAC IRAK4 degrader-12 (HY-168586) .

HY-159677

E3 Ligase Ligand-linker Conjugate 115	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 115 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 115 can be used to synthesize PROTAC SMARCA2/4-degrader-27 (HY-162834) .

HY-159679

E3 Ligase Ligand-linker Conjugate 116	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 116 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 116 can be used to synthesize PROTAC SMARCA2/4-degrader-28 (HY-162835) .

HY-159683A

E3 Ligase Ligand-linker Conjugate 119	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 119 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 119 can be used to synthesize PROTAC SMARCA2/4-degrader-31 (HY-162744) .

HY-159683

E3 Ligase Ligand-linker Conjugate 117	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 117 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 117 can be used to synthesize PROTAC SMARCA2/4-degrader-29 (HY-162743) .

HY-159685

E3 Ligase Ligand-linker Conjugate 118	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 118 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 118 can be used to synthesize PROTAC SMARCA2/4-degrader-30 (HY-162748) .

HY-168696

E3 Ligase Ligand-linker Conjugate 148	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 148 is an E3 Ligase Ligand-linker Conjugate for PROTAC synthesis. E3 Ligase Ligand-linker Conjugate 148 is compoused of an E3 Ligase Ligand (HY-W247437) and a linker (HY-W126831) .

HY-161638

E3 Ligase Ligand-linker Conjugate 108	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 108 is a E3 ligase ligand-linker conjugate, used for the the synthesis of PROTAC SOS1 degrader (HY-161634) .

HY-161640

E3 Ligase Ligand-linker Conjugate 109	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 109 is a E3 ligase ligand-linker conjugate, used for the the synthesis of PROTAC SOS1 degrader (HY-161636) .

HY-159733

E3 Ligase Ligand-linker Conjugate 120	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 120 is a conjugate of the E3 ubiquitin ligase ligand and linker of PROTAC PRMT3 degrader 1 (HY-159728) .

HY-W034918

Docosanedioic acid	ADC Linker PROTAC Linkers	Cancer
Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-168693

Target Protein Ligand-Linker Conjugates 2	Target Protein Ligand-Linker Conjugates
Target Protein Ligand-Linker Conjugates 2 is a conjugate of the Target Protein Ligand and Linker, consisting of Desmethyl-QCA276 (HY-44103) and the corresponding Linker. Target Protein Ligand-Linker Conjugates 2 can be used to synthesize PROTAC BD-9136 (HY-149878) .

HY-133046

VHL Ligand-Linker Conjugates 17	E3 Ligase Ligand-Linker Conjugates	Cancer
VHL Ligand-Linker Conjugates 17 incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 17 can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 is a highly potent androgen receptor (AR) PROTAC degrader . VHL Ligand-Linker Conjugates 17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-168254

E3 Ligase Ligand-linker Conjugate 127	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 127 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 127 can be used to synthesize PROTAC BRM/BRG1 degrader-3 (HY-168251) .

HY-129938

PROTAC BRD4 Degrader-24	PROTAC-Linker Conjugates for PAC	Cancer
PROTAC BRD4 Degrader-24 (compound 5), a PROTAC-linker Conjugate for PAC, comprises the chimeric BET degrader GNE-987 and disulfide-containing linker .

HY-126894

Bis-PEG9-acid	PROTAC Linkers ADC Linker	Cancer
Bis- PEG9- acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis- PEG9- acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-169976

E3 Ligase Ligand-linker Conjugate 140	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 140 (intermediate I-11) is an E3 ubiquitinase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 140 can be used to synthesize PROTAC AR Degrader-6 (HY-156751) .

HY-157587

E3 ligase Ligand-Linker Conjugate 29	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 29 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 29 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157588

(S)-Thalidomide-Piperazine-CH2-Pyrrolidine-C2-OH	Ligands for E3 Ligase Autophagy	Cancer
E3 ligase Ligand-Linker Conjugate 30 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 30 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

Cat. No.	Product Name		Classification

HY-141170

TCO-PEG12-NHS ester		TCO ADC Synthesis PROTAC Synthesis
TCO-PEG12-NHS ester is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-126458

Thalidomide-O-PEG2-propargyl E3 ligase Ligand-linker conjugates 32		Alkynes
Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology . Thalidomide-O-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130346

DBCO-PEG4-DBCO		ADC Synthesis PROTAC Synthesis DBCO
DBCO-PEG4-DBCO is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-159165

Pomalidomide-cyclopentane-amide-Alkyne		Alkynes
Pomalidomide-cyclopentane-amide-Alkyne is an E3 ligase ligand-linker conjugate that incorporates the Pomalidomide (HY-10984) and the linker cyclopentane-amide-Alkyne. Pomalidomide-cyclopentane-amide-Alkyne is used to form PROTACs, such as RGB110 (HY-159087) .

HY-124386

DBCO-NHCO-PEG4-amine		PROTAC Synthesis DBCO ADC Synthesis
DBCO-NHCO-PEG4-amine is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB−MMAE and DBCO-TRX−MMAE with EC₅₀s of 280 nM and 22 nM in SKBR3 cells, respectively) .

HY-130383

Propargyl-PEG7-acid		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG7-acid is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG7-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130386

Propargyl-PEG6-acid		ADC Synthesis Alkynes PROTAC Synthesis
Propargyl-PEG6-acid is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG6-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-139343

Pomalidomide 4'-alkylC2-azide		Azide
Pomalidomide 4'-alkylC2-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC2-azide can be used in the synthesis of PROTAC .

HY-139341

Pomalidomide 4'-alkylC3-azide		Azide
Pomalidomide 4'-alkylC3-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC3-azide can be used in the synthesis of PROTAC .

HY-125541

DBCO-NHCO-PEG4-acid		DBCO ADC Synthesis PROTAC Synthesis
DBCO-Amide-PEG5-acid is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-126976

Propargyl-PEG5-amine		ADC Synthesis PROTAC Synthesis Alkynes
Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs . Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130372

Propargyl-PEG9-bromide		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG9-bromide is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG9-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG9-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130377

Propargyl-PEG8-bromide		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG8-bromide is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130591

Propargyl-PEG4-Br		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG4-Br is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-116427

Propargyl-PEG4-thiol		PROTAC Synthesis ADC Synthesis Alkynes
Propargyl-PEG4-thiol is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-thiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-118808

Propargyl-PEG2-NHBoc		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs . Propargyl-PEG2-NHBoc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130387

Propargyl-PEG4-Tos		ADC Synthesis Alkynes PROTAC Synthesis
Propargyl-PEG4-Tos is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-118764

Propargyl-PEG2-acid		Alkynes ADC Synthesis PROTAC Synthesis
Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-acid is also a PEG-based **PROTAC linker** that can be used in the synthesis of PROTACs . Propargyl-PEG2-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-111456

DBCO-NHCO-PEG4-NHS ester		ADC Synthesis PROTAC Synthesis DBCO
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based **PROTAC linker** can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-126885

DBCO-PEG5-NHS ester		ADC Synthesis PROTAC Synthesis DBCO
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based **PROTAC linker** can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-126974

Propargyl-PEG3-NHS ester		PROTAC Synthesis Alkynes ADC Synthesis
Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130376

Propargyl-PEG8-NHS ester		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130381

Propargyl-PEG7-NHS ester		ADC Synthesis Alkynes PROTAC Synthesis
Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130385

Propargyl-PEG6-NHS ester		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130388

Propargyl-PEG5-NHS ester		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W051634

Propargyl-PEG2-amine		Alkynes PROTAC Synthesis ADC Synthesis
Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs . Propargyl-PEG2-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-139332

Pomalidomide 4'-PEG6-azide		Azide
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .

HY-130572

Azido-PEG5-acid		ADC Synthesis Azide PROTAC Synthesis
Azido-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs, such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)). Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-148556

Thalidomide-O-C6-azide		Azide
Thalidomide-O-C6-azide is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates) that incorporates the Thalidomide (Thalidomide (HY-14658)) based cereblon ligand and a linker used in PROTAC technology . Thalidomide-O-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-159608

PROTAC Cbl-b-IN-1		Azide
PROTAC Cbl-b-IN-1 (compound 64) is a PROTAC targeting Cbl-b. PROTAC Cbl-b-IN-1 is composed of PROTAC target protein ligand Cbl-b-IN-21 (HY-159615), PROTAC Linker Cbz-Pip-2C-Pip-C-Pip (HY-159617) and E3 ubiquitin ligase ligand (3S) Lenalidomide-5-Br (HY-W797329), where the E3 ubiquitin ligase ligand + Linker conjugate is (3S) Lenalidomide-5-Pip-C-Pip-2C-Pip (HY-159618) ^{[1] ^.}

HY-126884

DBCO-NHCO-PEG4-NH-Boc		ADC Synthesis PROTAC Synthesis DBCO
DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based **PROTAC linker** can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-130379

Propargyl-PEG8-acid		ADC Synthesis Alkynes PROTAC Synthesis
Propargyl-PEG8-acid is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria . Propargyl-PEG8-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-157510

Thalidomide-O-C3-azide		Azide
Thalidomide-O-C3-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C3-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C3-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of *PROTAC*s .

HY-157511

Thalidomide-O-C5-azide		Azide
Thalidomide-O-C5-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C5-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C5-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .

HY-140055

Thalidomide-PEG4-Propargyl		Alkynes
Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology . Thalidomide-PEG4-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-163647

Lenalidomide-COCH-PEG2-azido		Azide
Lenalidomide-COCH-PEG2-azido is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide (HY-A0003) based cereblon ligand and a linker. Lenalidomide-COCH-PEG2-azido can be used in the synthesis of PROTAC AKR1C3 degrader-1 (HY-163609) .

HY-130435

DBCO-PEG4-amine		DBCO PROTAC Synthesis ADC Synthesis
DBCO-PEG4-amine is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker) . DBCO-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-126676

DBCO-(PEG2-Val-Cit-PAB)2		PROTAC Synthesis DBCO ADC Synthesis
DBCO-(PEG2-Val-Cit-PAB)2 is a dual cleavable ADC linker for antibody-drug conjugates (ADCs). DBCO-(PEG2-Val-Cit-PAB)2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-(PEG2-Val-Cit-PAB)2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-130182

Propargyl-PEG8-NH2		ADC Synthesis PROTAC Synthesis Alkynes
Propargyl-PEG8-NH2 (compound 3b) is a PEG-based **PROTAC linker** can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140081

Boc-gly-PEG3-endo-BCN		ADC Synthesis BCN PROTAC Synthesis
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-157515

Thalidomide 4'-ether-PEG2-azide		Azide
Thalidomide 4'-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4'-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4'-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of *PROTACs* .

HY-101157

Propargyl-PEG5-acid		PROTAC Synthesis Alkynes ADC Synthesis
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based **PROTAC linker** that can be used in the synthesis of PROTACs . Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130475

Azido-PEG9-acid		Azide PROTAC Synthesis ADC Synthesis
Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG9-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-133736

PROTAC BRD4 Degrader-5-CO-PEG3-N3		Azide
PROTAC BRD4 Degrader-5-CO-PEG3-N3 (Compound 2) is a PROTAC-linker Conjugate for PAC, comprises the BRD4 degrader GNE-987 and PEG-based linker . PROTAC BRD4 Degrader-5-CO-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-159777

CPI-203-PEG5-Alkyne		Alkynes
CPI-203-PEG5-Alkyne is a conjugate of E3 ligase and linker. CPI-203-PEG5-Alkyne can be used for synthesis of PROTAC BRD4-DCAF1 degrader-1 (HY-169151) .

HY-128767

VH032-PEG3-acetylene		Alkynes
VH032-PEG3-acetylene is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in *PROTAC* technology . VH032-PEG3-acetylene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130169

Azido-PEG9-amine		ADC Synthesis PROTAC Synthesis Azide
Azido-PEG9-amine is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG9-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-130324

Azido-PEG7-amine		Azide ADC Synthesis PROTAC Synthesis
Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG7-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG7-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140454

Azido-PEG8-acid		ADC Synthesis PROTAC Synthesis Azide
Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-acid is also a PEG-based **PROTAC linker** that can be used in the synthesis of PROTACs . Azido-PEG8-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-113931

Aminooxy-PEG2-azide		ADC Synthesis PROTAC Synthesis Azide
Aminooxy-PEG2-azide is a PEG-based **PROTAC linker** that can be used in the synthesis of PROTACs . Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Aminooxy-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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