Tnf - tumor necrosis factor Gene

Mus musculus

Also known as DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha

Gene ID: 21926 | Gene type: protein coding

About Tnf

Chromosome 17: 35,418,357-35,420,983 reverse strand.GRCm39:CM001010.3

This gene has 2 transcripts (splice variants), 246 orthologues, 8 paralogues and is associated with 214 phenotypes. Broad expression in spleen adult (RPKM 4.1), thymus adult (RPKM 3.) and 16 other tissues.

Summary

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to Bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Tnf Products(2)

mRNA	Protein	Name
NM_013693.3	NP_038721.1	tumor necrosis factor isoform 1
NM_001278601.1	NP_001265530.1	tumor necrosis factor isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables cytokine activity	IDA IDA: Inferred from direct assay	11588035	MGI
enables cytokine activity	IGI IGI: Inferred from genetic interaction	16260493	MGI
enables death receptor agonist activity	IDA IDA: Inferred from direct assay	14985352	MGI
enables protease binding	IPI IPI: Inferred from physical interaction	12135759	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	16702408	MGI
enables receptor ligand activity	IDA IDA: Inferred from direct assay	2989794	MGI
enables tumor necrosis factor receptor binding	IDA IDA: Inferred from direct assay	11588035	MGI
enables tumor necrosis factor receptor binding	IPI IPI: Inferred from physical interaction	1645445	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of JNK cascade	IDA IDA: Inferred from direct assay	16260493	MGI
acts upstream of JNK cascade	IGI IGI: Inferred from genetic interaction	16260493	MGI
acts upstream of or within JNK cascade	IGI IGI: Inferred from genetic interaction	17015619	MGI
acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA IDA: Inferred from direct assay	16183742	MGI
acts upstream of or within animal organ morphogenesis	IMP IMP: Inferred from mutant phenotype	8879212	MGI
acts upstream of or within apoptotic signaling pathway	IDA IDA: Inferred from direct assay	8208546	MGI
acts upstream of or within cellular extravasation	IDA IDA: Inferred from direct assay	10528208	MGI
acts upstream of or within cellular response to amino acid stimulus	IDA IDA: Inferred from direct assay	20548288	MGI
acts upstream of or within cellular response to lipopolysaccharide	IDA IDA: Inferred from direct assay	19047410	MGI
involved in cellular response to lipopolysaccharide	IMP IMP: Inferred from mutant phenotype	29849090	MGI
involved in cellular response to type II interferon	IMP IMP: Inferred from mutant phenotype	29849090	MGI
acts upstream of or within defense response	IMP IMP: Inferred from mutant phenotype	8395024	MGI
acts upstream of or within defense response to Gram-positive bacterium	IGI IGI: Inferred from genetic interaction	9834074	MGI
acts upstream of or within defense response to bacterium	IDA IDA: Inferred from direct assay	10899905	MGI
involved in endothelial cell apoptotic process	IDA IDA: Inferred from direct assay	26808574	MGI
acts upstream of or within epithelial cell proliferation involved in salivary gland morphogenesis	IDA IDA: Inferred from direct assay	11241200	MGI
acts upstream of or within extracellular matrix organization	IDA IDA: Inferred from direct assay	15381731	MGI
acts upstream of or within extrinsic apoptotic signaling pathway	IGI IGI: Inferred from genetic interaction	19498109	MGI
acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors	IGI IGI: Inferred from genetic interaction	12431371	MGI
acts upstream of or within glucose metabolic process	IDA IDA: Inferred from direct assay	12068289	MGI
acts upstream of or within humoral immune response	IMP IMP: Inferred from mutant phenotype	8879212	MGI
acts upstream of or within inflammatory response	IGI IGI: Inferred from genetic interaction	21148126	MGI
involved in inflammatory response to wounding	IDA IDA: Inferred from direct assay	27830702	MGI
acts upstream of interleukin-6 production	IDA IDA: Inferred from direct assay	11894098	MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage	IDA IDA: Inferred from direct assay	17242187	MGI
acts upstream of or within leukocyte migration	IDA IDA: Inferred from direct assay	15034066	MGI
involved in macrophage activation involved in immune response	IMP IMP: Inferred from mutant phenotype	29849090	MGI
involved in microglial cell activation	IDA IDA: Inferred from direct assay	22950459	MGI
acts upstream of or within multicellular organism development	IMP IMP: Inferred from mutant phenotype	9368616	MGI
acts upstream of or within necroptotic signaling pathway	IGI IGI: Inferred from genetic interaction	19498109	MGI
acts upstream of or within negative regulation of D-glucose import	IDA IDA: Inferred from direct assay	12068289	MGI
involved in negative regulation of alkaline phosphatase activity	IDA IDA: Inferred from direct assay	21689636	MGI
involved in negative regulation of amyloid-beta clearance	IGI IGI: Inferred from genetic interaction	17255335	MGI
involved in negative regulation of endothelial cell proliferation	IDA IDA: Inferred from direct assay	26808574	MGI
acts upstream of or within negative regulation of gene expression	IDA IDA: Inferred from direct assay	26427354	MGI
involved in negative regulation of mitotic cell cycle	IDA IDA: Inferred from direct assay	26808574	MGI
acts upstream of or within negative regulation of myoblast differentiation	IMP IMP: Inferred from mutant phenotype	23844157	MGI
involved in negative regulation of osteoblast differentiation	IDA IDA: Inferred from direct assay	21689636	MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	9305915	MGI
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	21689636	MGI
acts upstream of or within osteoclast differentiation	IGI IGI: Inferred from genetic interaction	15485831	MGI
acts upstream of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA IDA: Inferred from direct assay	20080598	MGI
acts upstream of or within positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	12761567	MGI
acts upstream of or within positive regulation of JNK cascade	IDA IDA: Inferred from direct assay	16260493	MGI
acts upstream of or within positive regulation of JNK cascade	IGI IGI: Inferred from genetic interaction	16260493	MGI
involved in positive regulation of amide metabolic process	IDA IDA: Inferred from direct assay	10411298	MGI
involved in positive regulation of amyloid-beta formation	IDA IDA: Inferred from direct assay	17255335	MGI
involved in positive regulation of canonical NF-kappaB signal transduction	IDA IDA: Inferred from direct assay	2989794	MGI
involved in positive regulation of canonical NF-kappaB signal transduction	IGI IGI: Inferred from genetic interaction	7525730	MGI
involved in positive regulation of cellular metabolic process	IDA IDA: Inferred from direct assay	10411298	MGI
acts upstream of or within positive regulation of chronic inflammatory response to antigenic stimulus	IGI IGI: Inferred from genetic interaction	9834074	MGI
involved in positive regulation of fever generation	IDA IDA: Inferred from direct assay	19940926	MGI
involved in positive regulation of gene expression	IDA IDA: Inferred from direct assay	17255335	MGI
involved in positive regulation of hair follicle development	IMP IMP: Inferred from mutant phenotype	16702408	MGI
involved in positive regulation of heterotypic cell-cell adhesion	IDA IDA: Inferred from direct assay	26808574	MGI
acts upstream of or within positive regulation of humoral immune response mediated by circulating immunoglobulin	IGI IGI: Inferred from genetic interaction	9834074	MGI
acts upstream of or within positive regulation of interleukin-6 production	IDA IDA: Inferred from direct assay	11894098	MGI
involved in positive regulation of lipid metabolic process	IDA IDA: Inferred from direct assay	10411298	MGI
involved in positive regulation of neuron apoptotic process	IDA IDA: Inferred from direct assay	22950459	MGI
involved in positive regulation of non-canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	21689636	MGI
acts upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA IDA: Inferred from direct assay	20080598	MGI
involved in positive regulation of protein localization to plasma membrane	IMP IMP: Inferred from mutant phenotype	16547515	MGI
involved in positive regulation of synaptic transmission	IMP IMP: Inferred from mutant phenotype	16547515	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	9305915	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	18025219	MGI
acts upstream of or within positive regulation of translational initiation by iron	IDA IDA: Inferred from direct assay	11588035	MGI
acts upstream of or within positive regulation of type II interferon production	IGI IGI: Inferred from genetic interaction	9834074	MGI
involved in positive regulation of vascular associated smooth muscle cell proliferation	IDA IDA: Inferred from direct assay	26808574	MGI
acts upstream of or within regulation of branching involved in salivary gland morphogenesis	IDA IDA: Inferred from direct assay	11241200	MGI
acts upstream of or within regulation of branching involved in salivary gland morphogenesis	IMP IMP: Inferred from mutant phenotype	11241200	MGI
acts upstream of or within regulation of cell population proliferation	IDA IDA: Inferred from direct assay	11799106	MGI
acts upstream of or within regulation of immunoglobulin production	IDA IDA: Inferred from direct assay	12958312	MGI
acts upstream of or within regulation of inflammatory response	IDA IDA: Inferred from direct assay	24349514	MGI
involved in regulation of membrane lipid metabolic process	IDA IDA: Inferred from direct assay	10411298	MGI
involved in regulation of metabolic process	IGI IGI: Inferred from genetic interaction	7715705	MGI
acts upstream of or within regulation of osteoclast differentiation	IDA IDA: Inferred from direct assay	12490655	MGI
acts upstream of or within regulation of protein phosphorylation	IDA IDA: Inferred from direct assay	15169905	MGI
acts upstream of or within regulation of protein secretion	IDA IDA: Inferred from direct assay	19293336	MGI
acts upstream of or within regulation of reactive oxygen species metabolic process	IDA IDA: Inferred from direct assay	21052097	MGI
involved in regulation of synapse organization	IMP IMP: Inferred from mutant phenotype	16547515	MGI
acts upstream of or within tumor necrosis factor-mediated signaling pathway	IDA IDA: Inferred from direct assay	3898078	MGI
involved in tumor necrosis factor-mediated signaling pathway	IDA IDA: Inferred from direct assay	10411298	MGI
acts upstream of type II interferon production	IGI IGI: Inferred from genetic interaction	9834074	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in external side of plasma membrane	IDA IDA: Inferred from direct assay	16282525	MGI
is active in extracellular region	IDA IDA: Inferred from direct assay	25049354	MGI
is active in extracellular space	IDA IDA: Inferred from direct assay	14985352	MGI
located in extracellular space	IDA IDA: Inferred from direct assay	1577194	MGI
located in intracellular anatomical structure	IDA IDA: Inferred from direct assay	19723499	MGI
located in membrane raft	IDA IDA: Inferred from direct assay	17010968	MGI
located in phagocytic cup	IDA IDA: Inferred from direct assay	16282525	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	15155767	MGI
located in recycling endosome	IDA IDA: Inferred from direct assay	16282525	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Tnf Protein Structure

TNF

0
100
200
235 a.a.

Protein Preferred Names

Protein Names

tumor necrosis factor

cachectin	tumor necrosis factor ligand 1f
tumor necrosis factor ligand superfamily member 2	tumor necrosis factor-alpha

Recombinant Tnf Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7090	TNF-alpha/TNFSF2 Protein, Mouse (156a.a)	P06804 (L80-L235)	≥95%
HY-P7090A	TNF-alpha/TNFSF2 Protein, Mouse (P. pastoris)	P06804 (S84-L235)	≥95%
HY-P7417	TNF-alpha/TNFSF2 Protein, Mouse (His)	P06804 (L80-L235)	≥95%
HY-P70571	TNF-alpha/TNFSF2 Protein, Mouse (147a.a)	P06804 (D89-L235)	≥95%
HY-P7417AF	Animal-Free TNF-alpha/TNFSF2 Protein, Mouse (His)	P06804 (L80-L235)	≥95%
HY-P700510	TNF-alpha/TNFSF2 Protein, Mouse (His-SUMO)	P06804 (G57-L235)	≥95%

Related Agents

Approval

Bioactive Molecules (18)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12085	Apremilast		99.91%	Yes
HY-103399	Trovafloxacin mesylate	Inhibitor	99.56%	Unkown
HY-N0281	Daphnetin		99.86%	Unkown
HY-B1077	Penfluridol		99.93%	Unkown
HY-13682	Mifamurtide		≥99.0%	Unkown
HY-A0170	Trovafloxacin	Inhibitor	98.99%	Unkown
HY-B1201	Tiratricol	Inhibitor	99.60%	Yes
HY-30235A	Benzydamine hydrochloride	Inhibitor	98.22%	Unkown
HY-B0164	Mizolastine	Antagonist	99.82%	Unkown
HY-B0446	Naphazoline hydrochloride		98.12%	Unkown
HY-13682B	Mifamurtide sodium		98.19%	Unkown
HY-B0513	Methylthiouracil	Inhibitor	≥98.0%	Unkown
HY-111326A	Naphazoline nitrate		≥98.0%	Unkown
HY-13682C	Mifamurtide TFA		≥98.0%	Unkown
HY-B1615	Clenbuterol	Agonist	/	Unkown
HY-111326	Naphazoline		/	Unkown
HY-30235	Benzydamine	Inhibitor	/	Unkown
HY-B0164A	Mizolastine dihydrochloride	Antagonist	/	Unkown

Inhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9970	Infliximab	Inhibitor	90.30%	Unkown
HY-P9908	Adalimumab	Inhibitor	98.12%	Unkown
HY-108847	Etanercept	Inhibitor	99.20%	Unkown
HY-P9953	Certolizumab pegol	Inhibitor	99.30%	Unkown
HY-P99111	Golimumab		99.71%	Unkown
HY-P99796	Ozoralizumab	Inhibitor	99.80%	Unkown

Clinical Phase

Bioactive Molecules (25)

Cat. No.	Product Name	Effect	Purity	Phase
HY-N3021	D-chiro-Inositol	Inhibitor	≥98.0%	Phase 4
HY-N8277	Kdo2-Lipid A ammonium		99.00%	Phase 4
HY-114360AS1	Taurohyodeoxycholic acid-d4 sodium	Inhibitor	/	Phase 4
HY-11109	Resatorvid	Inhibitor	99.95%	Phase 3
HY-13743	Roquinimex	Inhibitor	99.69%	Phase 3
HY-13740	Resiquimod		99.95%	Phase 2
HY-16591	Birinapant		99.70%	Phase 2
HY-110133	JTE-607	Inhibitor	99.27%	Phase 2
HY-15509A	Semapimod tetrahydrochloride	Inhibitor	98.43%	Phase 2
HY-119307	Apratastat	Inhibitor	99.67%	Phase 2
HY-N9965	2'-Fucosyllactose	Inhibitor	99.95%	Phase 2
HY-145726	ISIS 104838	Inhibitor	/	Phase 2
HY-100376	CPI-1189	Inhibitor	98.49%	Phase 2
HY-105017	Evodenoson	Agonist	99.74%	Phase 2
HY-114766	Pumafentrine	Inhibitor	/	Phase 2
HY-18862	PF-03715455	Inhibitor	/	Phase 2
HY-U00179	CDC801	Inhibitor	98.94%	Phase 2
HY-10172	IMD-0354	Inhibitor	99.51%	Phase 1
HY-13518	Piceatannol		98.90%	Phase 1
HY-107390	AX-024	Inhibitor	99.29%	Phase 1
HY-19717	DCVC	Inhibitor	99.83%	Phase 1
HY-15507	VGX-1027	Inhibitor	99.76%	Phase 1
HY-107390A	AX-024 hydrochloride	Inhibitor	99.75%	Phase 1
HY-N0803	Myrcene	Inhibitor	≥75.0%	Phase 1
HY-N8691	2',6'-Dihydroxy-4'-methoxydihydrochalcone	Inhibitor	/	Phase 1

Inhibitory Antibodies (16)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99252	Itolizumab		/	Phase 3
HY-P990070	Zigakibart	Inhibitor	98.37%	Phase 3
HY-P99499	Cetrelimab		≥99.0%	Phase 3
HY-P99578	Tanfanercept	Inhibitor	/	Phase 3
HY-P99692	Lenercept	Inhibitor	/	Phase 3
HY-P99772	Onfekafusp alfa		/	Phase 3
HY-P99670	Iscalimab	Inhibitor	99.25%	Phase 2
HY-P99315	Ruplizumab	Inhibitor	99.84%	Phase 2
HY-P99810	Quisovalimab		96.18%	Phase 2
HY-P99940	Remtolumab	Inhibitor	99.24%	Phase 2
HY-P9983	Lintuzumab	Inhibitor	/	Phase 2
HY-P99704	Licaminlimab	Inhibitor	96.10%	Phase 2
HY-P99775	Placulumab	Inhibitor	/	Phase 2
HY-P99945	Revdofilimab	Activator	99.35%	Phase 1
HY-P99178	CTX-471		99.42%	Phase 1
HY-P99361	Enavatuzumab	Inhibitor	≥95.0%	Phase 1

Pre-clinical Phase

Bioactive Molecules (438)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13453	BAY 11-7082		99.98%	Unkown
HY-N0822	Shikonin	Inhibitor	99.80%	Unkown
HY-15648B	GSK-J4		99.64%	Unkown
HY-108473	CU-CPT 4a	Inhibitor	99.34%	Unkown
HY-P0224	N-Formyl-Met-Leu-Phe	Inhibitor	99.83%	Unkown
HY-103490	Takinib		98.92%	Unkown
HY-12326A	c-di-AMP disodium	Agonist	99.71%	Unkown
HY-110203	R-7050	Antagonist	98.55%	Unkown
HY-138682	STING-IN-2	Inhibitor	99.71%	Unkown
HY-13812	QNZ	Inhibitor	99.50%	Unkown
HY-123942	Diprovocim	Agonist	98.35%	Unkown
HY-P1860	TNF-α (31-45), human		99.77%	Unkown
HY-133122	UCB-9260	Inhibitor	99.96%	Unkown
HY-122882	HOIPIN-8		99.89%	Unkown
HY-109804	CORM-401	Inhibitor	98.27%	Unkown
HY-126360	Oxazolone		≥98.0%	Unkown
HY-13229	BOC-D-FMK	Inhibitor	≥95.0%	Unkown
HY-N0633	Muscone	Inhibitor	≥98.0%	Unkown
HY-100339	GSK583	Inhibitor	98.74%	Unkown
HY-156798	ADS032		99.74%	Unkown
HY-N0029	Forsythoside B		99.99%	Unkown
HY-15648F	GSK-J4 hydrochloride	Inhibitor	98.83%	Unkown
HY-N0297	Sinensetin	Inhibitor	99.87%	Unkown
HY-100211	TAPI-2	Inhibitor	99.46%	Unkown
HY-134471	TNF-α-IN-2	Inhibitor	98.75%	Unkown
HY-N6796	Manumycin A		99.27%	Unkown
HY-110353	CU-T12-9	Agonist	98.94%	Unkown
HY-N0194	Asiatic acid		99.40%	Unkown
HY-N0509	Astilbin		99.97%	Unkown
HY-N0472	Geraniin	Inhibitor	99.84%	Unkown
HY-107737	1,2-DLPC	Activator	≥98.0%	Unkown
HY-111255	SPD304	Inhibitor	99.35%	Unkown
HY-19744	T6167923	Inhibitor	99.08%	Unkown
HY-147141	HS-276	Inhibitor	98.59%	Unkown
HY-107427	PF-3644022	Inhibitor	99.65%	Unkown
HY-N0405	Orientin	Inhibitor	99.73%	Unkown
HY-N0043	Ginsenoside Rd	Inhibitor	99.88%	Unkown
HY-N0722	Neochlorogenic acid	Inhibitor	99.77%	Unkown
HY-142618	TNF-α-IN-6	Inhibitor	99.58%	Unkown
HY-125402	GSK-843		99.18%	Unkown
HY-N0619	Mulberroside A	Inhibitor	99.86%	Unkown
HY-148141	JPE-1375	Antagonist	99.94%	Unkown
HY-14622	Necrostatin 2	Inhibitor	99.92%	Unkown
HY-147045	UCB-5307	Inhibitor	97.37%	Unkown
HY-15511	Tyrphostin A9	Inhibitor	99.87%	Unkown
HY-19975	RN-1734	Antagonist	99.86%	Unkown
HY-N6607	Tryptanthrin		99.89%	Unkown
HY-150725	ODN 1585	Inducer	/	Unkown
HY-101448	TMI-1		99.59%	Unkown
HY-103360	J-113863	Antagonist	≥99.0%	Unkown
HY-N0936	Coixol	Inhibitor	99.58%	Unkown
HY-133807	Benpyrine	Inhibitor	99.74%	Unkown
HY-110177	SP-100030	Inhibitor	99.86%	Unkown
HY-N0042	Ginsenoside Rc		≥98.0%	Unkown
HY-N1949	Homoplantaginin	Inhibitor	99.90%	Unkown
HY-N7637	Tubuloside B	Inhibitor	99.95%	Unkown
HY-108642B	AMG-548 dihydrochloride	Inhibitor	99.91%	Unkown
HY-32018	Cot inhibitor-2	Inhibitor	99.65%	Unkown
HY-101849	Fasentin		≥98.0%	Unkown
HY-12700	RO5256390		98.75%	Unkown
HY-131249	MK2-IN-3	Inhibitor	99.58%	Unkown
HY-111255A	SPD304 dihydrochloride	Inhibitor	99.96%	Unkown
HY-156454	UCB-6876	Inhibitor	99.96%	Unkown
HY-N0316	Mollugin		99.48%	Unkown
HY-103435	Vialinin A	Inhibitor	99.89%	Unkown
HY-N0569	Madecassic acid	Inhibitor	99.23%	Unkown
HY-N2350	Cynaropicrin	Inhibitor	99.79%	Unkown
HY-N0604	Ginsenoside Rh1	Inhibitor	≥98.0%	Unkown
HY-125527	Resolvin D1		99.60%	Unkown
HY-P1832A	PTD-p65-P1 Peptide TFA		99.14%	Unkown
HY-124750	NecroX-7	Inhibitor	99.69%	Unkown
HY-W010201	Citronellol		98.60%	Unkown
HY-130252	YQ128	Inhibitor	99.83%	Unkown
HY-12511	SKF-86002	Inhibitor	99.66%	Unkown
HY-134911	HS-243	Inhibitor	99.88%	Unkown
HY-160412	TNFα activity modulator 3	Inhibitor	98.30%	Unkown
HY-104073	CAY10602	Activator	98.65%	Unkown
HY-118922	IW927	Antagonist	99.04%	Unkown
HY-123984	LTβR-IN-1	Activator	99.79%	Unkown
HY-P1847A	IKKγ NBD Inhibitory Peptide TFA		98.20%	Unkown
HY-B0392	(S)-(+)-Rolipram		99.77%	Unkown
HY-114360A	Taurohyodeoxycholic acid sodium	Inhibitor	99.60%	Unkown
HY-N4288	4-Methylesculetin	Inhibitor	98.21%	Unkown
HY-N7056	4'-Hydroxychalcone	Inhibitor	99.66%	Unkown
HY-128598	MD2-TLR4-IN-1	Inhibitor	99.62%	Unkown
HY-128686	KAG-308	Agonist	99.88%	Unkown
HY-113402A	Gamma-glutamylcysteine TFA		95.20%	Unkown
HY-152956	STING agonist-23	Agonist	99.16%	Unkown
HY-N0041	Ginsenoside Rb3	Inhibitor	99.12%	Unkown
HY-N2086	Ethyl palmitate	Inhibitor	99.05%	Unkown
HY-112275	TNF-α-IN-1	Inhibitor	99.42%	Unkown
HY-116626	SM-7368	Inhibitor	99.77%	Unkown
HY-139066	Punicic acid		≥98.0%	Unkown
HY-N0613	Sauchinone	Inhibitor	99.88%	Unkown
HY-N2055	Kaempferol 3-O-sophoroside		99.84%	Unkown
HY-12557	γ-Glutamylvaline		99.73%	Unkown
HY-128348	PK68	Inhibitor	99.92%	Unkown
HY-W082785A	L6H21		99.46%	Unkown
HY-N1356	Reticuline	Inhibitor	98.91%	Unkown
HY-N2110	Phellopterin		99.94%	Unkown
HY-N6246	Asperulosidic Acid	Inhibitor	99.72%	Unkown
HY-32015	Cot inhibitor-1	Inhibitor	98.45%	Unkown
HY-113953	Z-Asp-CH2-DCB	Inhibitor	99.28%	Unkown
HY-124151	Adenosine-2'-monophosphate	Activator	99.91%	Unkown
HY-131945	CU-115	Antagonist	99.55%	Unkown
HY-155998	NF-κB-IN-11	Inhibitor	98.42%	Unkown
HY-N0617	Sanggenon C		98.50%	Unkown
HY-107818	4-Hydroxychalcone	Inhibitor	99.73%	Unkown
HY-118694	TAPI-0	Inhibitor	98.01%	Unkown
HY-120823	PF-05381941	Inhibitor	99.73%	Unkown
HY-132248	C5 Lenalidomide	Inhibitor	99.62%	Unkown
HY-150725C	ODN 1585 sodium	Inducer	93.90%	Unkown
HY-100735	C 87	Inhibitor	98.06%	Unkown
HY-135674	SR-318	Inhibitor	99.89%	Unkown
HY-102040	Hispidol	Inhibitor	98.70%	Unkown
HY-19667A	BMS-561392 formate	Inhibitor	99.38%	Unkown
HY-12326B	c-di-AMP diammonium	Agonist	99.36%	Unkown
HY-N0358	1,4-Dicaffeoylquinic acid	Inhibitor	99.80%	Unkown
HY-N2252	Licarin A	Inhibitor	98.48%	Unkown
HY-N3316	Martynoside	Antagonist	≥99.0%	Unkown
HY-N6253	Pinoresinol	Inducer	98.35%	Unkown
HY-162734	BRD5075	Inhibitor	98.08%	Unkown
HY-N0506	Rosarin		99.94%	Unkown
HY-N1987	Cucurbitacin IIb	Inducer	99.74%	Unkown
HY-N9445	Lacto-N-neotetraose		99.71%	Unkown
HY-P2612A	WP9QY TFA	Antagonist	99.83%	Unkown
HY-12326	c-di-AMP	Agonist	99.29%	Unkown
HY-133807A	(Rac)-Benpyrine	Inhibitor	99.30%	Unkown
HY-147263	Dovramilast	Inhibitor	99.83%	Unkown
HY-110077	API-1		99.62%	Unkown
HY-N0907	Ginsenoside Rg6		99.13%	Unkown
HY-N2855	Alphitolic acid		≥97.0%	Unkown
HY-N3063	Pimaric acid		99.83%	Unkown
HY-N4323	14-Deoxyandrographolide	Inhibitor	99.47%	Unkown
HY-141582	Ceramide 3		≥98.0%	Unkown
HY-N0857	Deoxyandrographolide	Activator	99.87%	Unkown
HY-N0906	Ginsenoside Rk3	Inhibitor	98.85%	Unkown
HY-N3807	Enniatin B1	Inhibitor	99.34%	Unkown
HY-N6857	Armepavine	Inhibitor	99.53%	Unkown
HY-N9315	Episappanol	Inhibitor	98.57%	Unkown
HY-P3722A	Mca-PLAQAV-Dpa-RSSSR-NH2 TFA		99.21%	Unkown
HY-101041	(E)-AG 556	Inhibitor	99.92%	Unkown
HY-13740S	Resiquimod-d5		99.84%	Unkown
HY-150612	(R)-STU104	Inhibitor	99.91%	Unkown
HY-112389	p38 MAP Kinase Inhibitor III	Inhibitor	98.77%	Unkown
HY-129113	α-Chaconine	Inhibitor	99.04%	Unkown
HY-145498	HDMAPP triammonium	Activator	≥90.0%	Unkown
HY-145726A	ISIS 104838 sodium		93.70%	Unkown
HY-148454	Necroptosis-IN-3	Inhibitor	99.77%	Unkown
HY-P3585	Epobis	Inhibitor	99.34%	Unkown
HY-123194	SIRT2/6-IN-1	Inhibitor	98.44%	Unkown
HY-157325	RIPK2-IN-5	Inhibitor	99.73%	Unkown
HY-131707	LEO 39652	Inhibitor	99.51%	Unkown
HY-110246	Quin C1		98.47%	Unkown
HY-112456	IKK2-IN-4	Inhibitor	99.89%	Unkown
HY-151966	TD1092		99.49%	Unkown
HY-152959	STING agonist-26	Agonist	99.56%	Unkown
HY-N1940	β-Anhydroicaritin	Inhibitor	99.09%	Unkown
HY-N3595	Cleomiscosin A	Inhibitor	99.15%	Unkown
HY-N4285	Negletein	Inhibitor	99.55%	Unkown
HY-N6073	Soyasapogenol A	Inhibitor	99.06%	Unkown
HY-N6927	Isoforskolin	Inhibitor	≥98.0%	Unkown
HY-P1860A	TNF-α (31-45), human TFA		/	Unkown
HY-P2320	IDR-1	Inhibitor	99.01%	Unkown
HY-150219A	ODN M326 sodium	Inhibitor	/	Unkown
HY-106359A	Delmitide acetate	Inhibitor	98.55%	Yes
HY-108623	Atizoram	Inhibitor	96.3%	Unkown
HY-117082	UTL-5g	Inhibitor	99.92%	Unkown
HY-12085S	Apremilast-d5		98.63%	Unkown
HY-122786	3-O-Methylviridicatin	Inhibitor	/	Unkown
HY-123936	SR12343	Inhibitor	/	Unkown
HY-125527S	Resolvin D1-d5		99.2%	Unkown
HY-129151	Ganoderic acid C1		≥95.0%	Unkown
HY-133807B	(R)-Benpyrine		99.17%	Unkown
HY-135808	BIZ 114	Inhibitor	≥98.0%	Unkown
HY-147086	CAY10789		99.84%	Unkown
HY-147506	NOD2 antagonist 1	Antagonist	99.57%	Unkown
HY-147696	SMTIN-T140		99.58%	Unkown
HY-151369	AV123	Inhibitor	99.60%	Unkown
HY-151876	Glucocorticoid receptor modulator 1		99.79%	Unkown
HY-153579	Anti-inflammatory agent 42	Inhibitor	≥98.0%	Unkown
HY-156025	HCAR2 agonist 1		/	Unkown
HY-160178	Glucocorticoid receptor agonist-3 Ala-Ala-Mal		99.72%	Unkown
HY-160179	Glucocorticoid receptor agonist-4	Agonist	99.80%	Unkown
HY-161016	TNF/IFN-γ-IN-1	Inhibitor	99.39%	Unkown
HY-169004	CBT-295	Inhibitor	99.34%	Unkown
HY-18754A	FR 167653	Inhibitor	99.87%	Unkown
HY-N0569R	Madecassic acid (Standard)	Inhibitor	/	Unkown
HY-N0619A	cis-Mulberroside A	Inhibitor	≥96.0%	Unkown
HY-N0811	Anemarsaponin B	Inhibitor	/	Unkown
HY-N8413	Chlojaponilactone B	Inhibitor	≥98.0%	Unkown
HY-P1875A	TNF-α (46-65), human TFA		99.20%	Unkown
HY-P3149B	LEESGGGLVQPGGSMK acetate		99.01%	Unkown
HY-P3203A	DSTYSLSSTLTLSK TFA		98.11%	Unkown
HY-114531	Lomifylline		99.67%	Unkown
HY-118157	3,5,7-Trimethoxyflavone		98.94%	Unkown
HY-156060	NCI126224	Inhibitor	99.88%	Unkown
HY-W013557	3-Hydroxyxanthone	Inhibitor	≥98.0%	Unkown
HY-131340	LASSBio-1632	Inhibitor	/	Unkown
HY-132195	RORγt inverse agonist 14	Inhibitor	/	Unkown
HY-19667	BMS-561392	Inhibitor	/	Unkown
HY-100211A	(R)-TAPI-2	Control	/	Unkown
HY-100702	SH-5		/	Unkown
HY-101961	Tyrphostin AG 1288	Inhibitor	98.68%	Unkown
HY-106359	Delmitide	Inhibitor	/	Unkown
HY-108162A	Ataquimast	Inhibitor	/	Unkown
HY-108641	SKF-86002 dihydrochloride	Inhibitor	/	Unkown
HY-108642A	AMG-548 hydrochloride	Inhibitor	/	Unkown
HY-108953	(S)-Quinolactacine A	Inhibitor	/	Unkown
HY-111317	SIRT1 activator 3	Activator	/	Unkown
HY-114221	Org 48762-0	Inhibitor	99.99%	Unkown
HY-114592	M199		/	Unkown
HY-114981	SRTCX1002	Activator	/	Unkown
HY-115351	GW-3333	Inhibitor	/	Unkown
HY-115913	PDE4-IN-6	Inhibitor	/	Unkown
HY-115976	COX-2-IN-10	Inhibitor	/	Unkown
HY-117356A	MRS2693 ammonium		/	Unkown
HY-118101	15-Deoxy-Δ12,14-prostaglandin A1		/	Unkown
HY-120041	ND-2158	Inhibitor	/	Unkown
HY-120600	Sibiriline	Inhibitor	/	Unkown
HY-121401	Myrtenal		/	Unkown
HY-121996	Prostaglandin E2 Ethanolamide		/	Unkown
HY-122292	Celastramycin A	Inhibitor	/	Unkown
HY-122521	Sootepin D	Inhibitor	/	Unkown
HY-123542	ONO-3403		/	Unkown
HY-123736	Ro 32-7315	Inhibitor	/	Unkown
HY-124003	Phytomonic acid		/	Unkown
HY-124388	PDE4-IN-20		/	Unkown
HY-126026	NF-κB-IN-17	Inhibitor	/	Unkown
HY-126414	Methylenedihydrotanshinquinone		/	Unkown
HY-128423AS	Tylvalosin-d9		/	Unkown
HY-134950	(E)-C-HDMAPP ammonium	Activator	/	Unkown
HY-136010	RIP2 Kinase Inhibitor 4	Inhibitor	/	Unkown
HY-142069	KB-R7785	Inhibitor	/	Unkown
HY-142958	NF-κB-IN-2		/	Unkown
HY-14305	BMS-582949		/	Unkown
HY-143410	Anti-inflammatory agent 16	Inhibitor	/	Unkown
HY-144368	CO delivery molecule 1		/	Unkown
HY-144727	Anti-inflammatory agent 11	Inhibitor	/	Unkown
HY-144737	Anti-inflammatory agent 15	Inhibitor	/	Unkown
HY-145492	Δ7(Z)-C14-HSL		/	Unkown
HY-146419	Anti-inflammatory agent 20	Inhibitor	/	Unkown
HY-146435	Anti-inflammatory agent 22	Inhibitor	/	Unkown
HY-146483	Anti-Aβ agent 1A	Inhibitor	/	Unkown
HY-146547	Anti-inflammatory agent 17	Inhibitor	/	Unkown
HY-146723	IKKβ-IN-1	Inhibitor	/	Unkown
HY-146765	AMS-17	Inhibitor	/	Unkown
HY-147078	EJMC-1	Inhibitor	99.69%	Unkown
HY-147697	LSD1-IN-21	Inhibitor	/	Unkown
HY-147712	PKC-IN-4	Inhibitor	/	Unkown
HY-147924	Keap1-Nrf2-IN-11	Inhibitor	/	Unkown
HY-147950	PDE4-IN-10	Inhibitor	/	Unkown
HY-148606	STING modulator-3	Inhibitor	/	Unkown
HY-148908	TNF-α-IN-8	Inhibitor	/	Unkown
HY-149331	TNF-α-IN-11	Inhibitor	/	Unkown
HY-149485	JNK2-IN-1	Inhibitor	/	Unkown
HY-149816	Anti-inflammatory agent 41	Inhibitor	/	Unkown
HY-149984	MAO-B-IN-21	Inhibitor	/	Unkown
HY-150219	ODN M326	Agonist	/	Unkown
HY-150725A	Biotin-labeled ODN 1585 sodium		/	Unkown
HY-150725B	FITC-labeled ODN 1585 sodium	Inducer	/	Unkown
HY-151188	DHU-Se1	Inhibitor	/	Unkown
HY-152213	BET-IN-13	Inhibitor	/	Unkown
HY-152957	STING agonist-24	Agonist	/	Unkown
HY-152958	STING agonist-25	Agonist	/	Unkown
HY-152961	STING agonist-28	Agonist	/	Unkown
HY-153329	TNF-α-IN-9	Inhibitor	/	Unkown
HY-153330	TNF-α-IN-10	Inhibitor	/	Unkown
HY-153952	Immuno modulator-1	Inhibitor	/	Unkown
HY-154698	Homouridine		/	Unkown
HY-155027	DPP-4-IN-8	Inhibitor	/	Unkown
HY-15509	Semapimod	Inhibitor	/	Unkown
HY-155179	ZMF-23	Inhibitor	/	Unkown
HY-155199	PDE1-IN-5	Inhibitor	/	Unkown
HY-155243	12R-LOX-IN-1	Inhibitor	/	Unkown
HY-155405	Anti-inflammatory agent 64	Inhibitor	/	Unkown
HY-155753	Anti-inflammatory agent 50	Inhibitor	/	Unkown
HY-155759	HMGB1-IN-2	Inhibitor	/	Unkown
HY-155820	Anti-inflammatory agent 54	Inhibitor	/	Unkown
HY-155821	Anti-inflammatory agent 55	Inhibitor	/	Unkown
HY-15616	BMS-470539	Agonist	/	Unkown
HY-156297	β5i-IN-1	Inhibitor	/	Unkown
HY-156367	RIPK1-IN-16	Inhibitor	/	Unkown
HY-157456	RIPK1-IN-19	Inhibitor	≥98.0%	Unkown
HY-157546	VEGFR-2-IN-40	Inhibitor	/	Unkown
HY-157809	Anti-inflammatory agent 74	Inhibitor	/	Unkown
HY-157992	LM-021	Inhibitor	/	Unkown
HY-159100	PVP-037	Agonist	/	Unkown
HY-159516	Sabialimon P	Inhibitor	/	Unkown
HY-159614	PG-PS	Activator	/	Unkown
HY-159669	Stercobilin hydrochloride (mixture of isomers)	Inhibitor	/	Unkown
HY-159884	MG-T-19		/	Unkown
HY-160027	TNF-alpha-IN-1	Inhibitor	/	Unkown
HY-160180	Glucocorticoid receptor agonist-4 Ala-Ala-Mal		/	Unkown
HY-160231	ssRNA42 sodium	Activator	/	Unkown
HY-160433	TNF-α-IN-12	Inhibitor	/	Unkown
HY-160434	TNF-α-IN-13	Inhibitor	/	Unkown
HY-160435	TNF-α-IN-14	Inhibitor	/	Unkown
HY-160436	TNF-α-IN-15	Inhibitor	/	Unkown
HY-160437	TNF-α-IN-16	Inhibitor	/	Unkown
HY-161240	MAO-B-IN-30	Inhibitor	98.53%	Unkown
HY-161381	PDE4-IN-15	Inhibitor	/	Unkown
HY-161520	Glucocorticoid receptor/NF-κB modulator-1		/	Unkown
HY-161620	DW18134	Inhibitor	/	Unkown
HY-161629	TLR8 agonist 7	Agonist	/	Unkown
HY-161630	TLR8 agonist 8	Agonist	/	Unkown
HY-161631	TLR8 agonist 9	Agonist	/	Unkown
HY-161674	Monoamine Oxidase B inhibitor 4	Inhibitor	/	Unkown
HY-161757	Anti-inflammatory agent 86		/	Unkown
HY-161833	HSP90-IN-31	Inhibitor	/	Unkown
HY-161901	BC-1293	Inhibitor	/	Unkown
HY-161936	Z21115	Inhibitor	/	Unkown
HY-161991	Caspase-3 activator 4		/	Unkown
HY-162097	RIPK1-IN-20	Inhibitor	/	Unkown
HY-162116	TLR7 agonist 18	Agonist	/	Unkown
HY-162316	NF-κB-IN-15	Inhibitor	/	Unkown
HY-162599	Spirohypertone B	Inhibitor	/	Unkown
HY-162600	CDK8-IN-15	Inhibitor	/	Unkown
HY-162641	AF-45	Inhibitor	/	Unkown
HY-162649	TIC10g	Inhibitor	/	Unkown
HY-162797	PDE4-IN-18	Inhibitor	/	Unkown
HY-162850	DOR agonist 2		/	Unkown
HY-162861	3-Methyl-chuangxinmycin	Inhibitor	/	Unkown
HY-162963	PPARδ agonist 11	Agonist	/	Unkown
HY-163102	IA-14069		/	Unkown
HY-163280	JGB-1-155	Activator	/	Unkown
HY-163368	HDAC6-IN-34	Inhibitor	/	Unkown
HY-163670	TLR7 agonist 21	Inhibitor	/	Unkown
HY-163673	Glucocorticoid receptor modulator 4	Modulator	/	Unkown
HY-163747	VEGFR-2-IN-47	Inhibitor	/	Unkown
HY-163748	GSK-3β inhibitor 17	Inhibitor	/	Unkown
HY-163755	GPER activator 1		/	Unkown
HY-163777	Talaroterphenyl A	Inhibitor	/	Unkown
HY-163998	TLR4-IN-1		/	Unkown
HY-164102	TNF-α-IN-18	Inhibitor	/	Unkown
HY-164893	ABBV-154	Inhibitor	/	Unkown
HY-164894	ABBV-3373	Inhibitor	/	Unkown
HY-167877	PS-166276	Inhibitor	/	Unkown
HY-168130	TNF-α/IL-1β-IN-1	Inhibitor	/	Unkown
HY-169103	Neuroprotective agent 5	Inhibitor	/	Unkown
HY-18754	FR 167653 free base	Inhibitor	/	Unkown
HY-18759	BMS-751324	Inhibitor	/	Unkown
HY-19717S	DCVC-13C3,15N		/	Unkown
HY-N0041R	Ginsenoside Rb3 (Standard)	Inhibitor	/	Unkown
HY-N0043R	Ginsenoside Rd (Standard)	Inhibitor	/	Unkown
HY-N0604R	Ginsenoside Rh1 (Standard)	Inhibitor	/	Unkown
HY-N0803S	Myrcene-d6	Inhibitor	/	Unkown
HY-N0976	1,11b-Dihydro-11b-hydroxymedicarpin		/	Unkown
HY-N10009	Cudraflavone B		/	Unkown
HY-N10047	7,8-Didehydrocimigenol	Inhibitor	/	Unkown
HY-N10448	Sinulatumolin E	Inhibitor	/	Unkown
HY-N10453	Sinulatumolin D		/	Unkown
HY-N10454	Sinulatumolin C	Inhibitor	/	Unkown
HY-N10835	Gnetumontanin B		/	Unkown
HY-N1125	Triptobenzene H		/	Unkown
HY-N11768	4-Methoxylonchocarpin	Inhibitor	/	Unkown
HY-N11892	7-O-Methylaloesinol	Inhibitor	/	Unkown
HY-N11996	Aloenin aglycone		/	Unkown
HY-N12042	Taxamairin B	Inhibitor	/	Unkown
HY-N12186	Sibiricine		/	Unkown
HY-N12653	Exserohilone	Inhibitor	/	Unkown
HY-N12743	Farobin A	Inhibitor	/	Unkown
HY-N13114	8-Gingerdione		/	Unkown
HY-N1326	Santamarine		/	Unkown
HY-N3364	Lucidone	Inhibitor	/	Unkown
HY-N3380	Linderaspirone A	Inhibitor	/	Unkown
HY-N3421	Koaburaside	Inhibitor	/	Unkown
HY-N3552	Catalposide	Inhibitor	≥98.0%	Unkown
HY-N3625	Coronalolic acid	Inhibitor	/	Unkown
HY-N4061	Hedycoronen A	Inhibitor	/	Unkown
HY-N4275	Oleaside A		/	Unkown
HY-N6969A	Dicentrine hydrochloride	Antagonist	/	Unkown
HY-N7699A	D-Trimannuronic acid	Activator	/	Unkown
HY-N8371	Shizukaol B	Inhibitor	/	Unkown
HY-N8593	Undecane	Inhibitor	≥98.0%	Unkown
HY-N8593S	Undecane-d24		/	Unkown
HY-N8816	Stipuleanoside R2		/	Unkown
HY-N8936	Narchinol B		/	Unkown
HY-N9000	Loganic acid 6′-O-β-D-glucoside		/	Unkown
HY-N9587	Tricin 7-O-β-D-glucopyranoside	Inducer	/	Unkown
HY-N9699	8α-Hydroxyhirsutinolide	Inhibitor	/	Unkown
HY-N9867	Gnetifolin E	Inhibitor	/	Unkown
HY-P10241	Ac-LEHD-CHO	Inhibitor	/	Unkown
HY-P10350	PapRIV	Agonist	/	Unkown
HY-P10354	SPA4		/	Unkown
HY-P10693	CZEN-002	Inhibitor	/	Unkown
HY-P1832	PTD-p65-P1 Peptide		/	Unkown
HY-P1847	IKKγ NBD Inhibitory Peptide		/	Unkown
HY-P2612	WP9QY	Antagonist	/	Unkown
HY-P3149	LEESGGGLVQPGGSMK		/	Unkown
HY-P3149A	LEESGGGLVQPGGSMK TFA		/	Unkown
HY-P3722	Mca-PLAQAV-Dpa-RSSSR-NH2		/	Unkown
HY-RS14784	TNF Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS14785	Tnf Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS14786	TNF Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W010201R	Citronellol (Standard)		/	Unkown
HY-W014049	N'-Nitro-D-arginine	Inhibitor	/	Unkown
HY-W104821	Rosolic acid	Activator	/	Unkown
HY-10320A	Doramapimod hydrochloride	Inhibitor	/	Unkown
HY-108162	Ataquimast free base	Inhibitor	/	Unkown
HY-110133A	JTE-607 free base	Inhibitor	/	Unkown
HY-110343	DBM 1285 dihydrochloride	Inhibitor	/	Unkown
HY-116426	IDT	Modulator	/	Unkown
HY-117569	KF24345 free base	Inhibitor	/	Unkown
HY-117622	ND-2110	Inhibitor	/	Unkown
HY-118316	GSK223	Inhibitor	/	Unkown
HY-118984	CRX-526	Antagonist	/	Unkown
HY-119799	UK-500001	Inhibitor	/	Unkown
HY-121200	Azadirone		/	Unkown
HY-122566	SMU127		/	Unkown
HY-12348	LEO 29102	Inhibitor	/	Unkown
HY-123882	IRAK4-IN-29		/	Unkown
HY-125980	LX-3	Inhibitor	/	Unkown
HY-126211	KBH-A42	Inhibitor	/	Unkown
HY-137370	2-Hexynyl-5′-N-ethylcarboxamidoadenosine		/	Unkown
HY-138063	Siegeskaurolic acid	Inhibitor	/	Unkown
HY-156431	Anti-inflammatory agent 61	Inhibitor	/	Unkown
HY-158650	10-OAHSA	Inhibitor	/	Unkown
HY-162579	TLR7 agonist 22	Agonist	/	Unkown
HY-163642	TNF-α agonistic 1		/	Unkown
HY-163712	17-Epiestriol	Agonist	/	Unkown
HY-16658C	Z-VA-DL-D-FMK	Inhibitor	/	Unkown
HY-169118	EGR-1-IN-2	Inhibitor	/	Unkown
HY-20070	BMS-566394	Inhibitor	/	Unkown
HY-N1159	Teuclatriol	Inhibitor	/	Unkown
HY-N11994	Aloeresin G	Inhibitor	/	Unkown
HY-N12116	Maceneolignan A	Inhibitor	/	Unkown
HY-N12905	Celastramycin A (isomer)	Inhibitor	/	Unkown
HY-N13184	Giraldoid B	Inhibitor	/	Unkown
HY-N8015S1	Octanal-d2	Inhibitor	/	Unkown
HY-N9541	Chaetoglobosin Vb		/	Unkown
HY-W015879S	2-Heptanol-d5	Inhibitor	/	Unkown
HY-W030338	aPKC-IN-2		/	Unkown
HY-W071581	Glucocorticoid receptor activator 1	Activator	/	Unkown
HY-W322573	(R)-Ketoprofen		/	Unkown
HY-W505984	TPNA10168	Activator	/	Unkown
HY-W753791	(±)-Perillaldehyde		/	Unkown
HY-W923189	Neral	Inhibitor	/	Unkown

Inhibitory Antibodies (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990008	Atrosab		96.93%	Unkown
HY-P99148	Anti-Mouse TNF alpha Antibody (TN3-19.12)	Inhibitor	95.00%	Unkown
HY-P9970A	Infliximab (Anti-TNF-α)	Inhibitor	/	Unkown
HY-P99782	Opinercept	Inhibitor	/	Unkown
HY-P99565	Tengonermin	Inhibitor	/	Unkown
HY-P99753	Nerelimomab	Inhibitor	/	Unkown
HY-P9S0009	Adalimumab (Powder)	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tnf	NCBI	NCBI:7124
Canis familiaris	Tnf	NCBI	NCBI:403922
Macaca fascicularis	Tnf	NCBI	NCBI:102139631
Susscrofa domestica	Tnf	NCBI
Leporidae	Tnf	NCBI
Rattus norvegicus	Tnf	NCBI	NCBI:24835
Macaca mulatta	Tnf	NCBI	NCBI:715467

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