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polymerization

" in MedChemExpress (MCE) Product Catalog:

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-143446

*Tubulin polymerization-IN-7*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-7 (compound 5) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-7 has the potential for the research of cancer diseases .

HY-145868

*Tubulin polymerization-IN-3*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-3 (compound 4c) is a potent tubulin polymerization inhibitor, with an IC₅₀ of 3.84 µM. Tubulin polymerization-IN-3 can induce apoptosis in colon cancer cells .

HY-Y0850U2

*PVA (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization)* Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization) (Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization)) is a biodegradable of polymer. PVA (Mw 130000, 87-89% hydrolyzed, ～2700 polymerization) can be used to blend with various biopolymers and hydrophilic synthetic polymers to improve mechanical properties of films .

HY-146362

*Tubulin polymerization-IN-17*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-17 (compound 23g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-17 exhibits tubulin depolymerization and induced cell apoptosis and inhibits migration. Tubulin polymerization-IN-17 has the potential for the research of cancer diseases .

HY-147896

*Tubulin polymerization-IN-29*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-29 (compound 6g) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-29 exhibits potent antiproliferative activity. Tubulin polymerization-IN-29 can induce HeLa cells arrest in G2/M phase .

HY-146377

*Tubulin polymerization-IN-19*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-19 (compound 4) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers .

HY-146378

*Tubulin polymerization-IN-20*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-20 (compound 11) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers .

HY-146376

*Tubulin polymerization-IN-18*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-18 (compound 8) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-18 has the potential for the research of breast cancers and chemoresistant colon cancers .

HY-Y0850U1

*PVA (Mw 61000, 98-99% hydrolyzed, ～1400 polymerization)* Polyvinyl alcohol (Mw 61000, 98-99% hydrolyzed, ～1400 polymerization); Poly(Ethenol) (Mw 61000, 98-99% hydrolyzed, ～1400 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 61000, 98-99% hydrolyzed, ～1400 polymerization) (Polyvinyl alcohol (Mw 61000, 98-99% hydrolyzed, ～1400 polymerization); Poly(Ethenol) (Mw 61000, 98-99% hydrolyzed, ～1400 polymerization)) is a biodegradable of polymer. PVA (Mw 61000, 98-99% hydrolyzed, ～1400 polymerization) can be used to produce bio-composite films .

HY-146310

*Tubulin polymerization-IN-15*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-15 (compound 4) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-15 has the potential for the research of cancer diseases .

HY-146211

*Tubulin polymerization-IN-14*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-14 (Compound 20a) is a tubulin polymerization inhibitor with an IC₅₀ of 3.15 μM. Tubulin polymerization-IN-14 shows potent anti-vascular and anticancer activities, induces cancer cell apoptosis .

HY-151982

*Tubulin polymerization-IN-39*	Microtubule/Tubulin	Cardiovascular Disease Cancer
Tubulin polymerization-IN-39 is a tubulin polymerization inhibitor (IC₅₀: 4.9 μM). Tubulin polymerization-IN-39 occupies the colchicine-binding site. Tubulin polymerization-IN-39 inhibits cancer cell proliferation .

HY-162126

*Tubulin polymerization-IN-58*	Microtubule/Tubulin YAP	Cancer
Tubulin polymerization-IN-58 (Compound K18) is a tubulin polymerization inhibitor with an IC₅₀ of 0.446 μM. Tubulin polymerization-IN-58 also induces the degradation of oncogenic protein YAP via the UPS pathway, thus can be used for cancer research .

HY-143447

*Tubulin polymerization-IN-8*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-8 (compound IIc) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-8 concentration-dependently causes cell cycle arrest at the G2/M phase in HCT116 tumor cells, and displays a significant inhibition of tubulin polymerization with an IC₅₀ value of 12.7 μM. Tubulin polymerization-IN-8 has the potential for the research of cancer diseases ^{[ 1]}.

HY-156737

*Tubulin polymerization-IN-49*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-49 (compound 12d) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-49 bound to colchicine site on tubulin and inhibited tubulin polymerization. Tubulin polymerization-IN-49 induces cell cycle arrest at G2/M phase and apoptosis. Tubulin polymerization-IN-49 has anticancer active and prevents tumor generation, inhibits tumor proliferation and angiogenesis .

HY-146164

*Tubulin polymerization-IN-21*	Microtubule/Tubulin	Metabolic Disease Cancer
Tubulin polymerization-IN-21 (compound 9a) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-21 exhibits anti-cancer activity through disrupting cellular integrity and affecting glucose metabolism .

HY-149363

*Tubulin polymerization-IN-43*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-43 disrupts cellular microtubule networks by targeting the Colchicine (HY-16569) site, and promots cell cycle arrest of leukemia cells at G2/M phase and cell apoptosis, as well as inhibiting angiogenesis .

HY-147824

*Tubulin polymerization-IN-22*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-22 is a tubulin polymerization inhibitor with an IC₅₀ of 8.1 μM. Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase and induces apoptosis .

HY-146311

*Tubulin polymerization-IN-16*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC₅₀ values of 0.084-0.221 μM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells .

HY-155314

*Tubulin polymerization-IN-50*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-50 (compound 7n) is a inhibitor of tubulin polymerization, with the IC₅₀ of 5.05 μM in SK-Mel-28 cells. Tubulin polymerization-IN-50 induces the cell cycle arrest in the G2/M phase .

HY-152143

*Tubulin polymerization-IN-41*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-41 is a potent tubulin polymerization inhibitor with the IC₅₀ of 2.61 μM. Tubulin polymerization-IN-41 targets the Colchicine-binding site of tubulin. Tubulin polymerization-IN-41 has anticancer effects .

HY-146863

*Tubulin polymerization-IN-10*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-10 is a potent tubulin polymerization inhibitor with an IC₅₀ of 4.25±0.75 μM. Tubulin polymerization-IN-10 has anti-tumor effects .

HY-155139

*Tubulin polymerization-IN-45*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-45, a tubulin-targeting agent, is a tubulin polymerization inhibitor. Tubulin polymerization-IN-45 binds to the colchicine site of tubulin. Tubulin polymerization-IN-45 induces apoptotic cell death in hepatocellular cancer (HCC) cells .

HY-Y0850U

*PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)* Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) (Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)) is a biocompatible, biodegradable, nontoxic and hydrophilic synthetic polymer. PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) can be used to produce bone tissue engineering scaffold ^[1]

HY-Y0850U3

*PVA (Mw 125000, 98-99% hydrolyzed, ～2800 polymerization)* Polyvinyl alcohol (Mw 125000, 98-99% hydrolyzed, ～2800 polymerization); Poly(Ethenol) (Mw 125000, 98-99% hydrolyzed, ～2800 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 125000, 98-99% hydrolyzed, ～2800 polymerization) is a polyvinyl alcohol with molecular weight of 125000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 125000, 98-99% hydrolyzed, ～2800 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .

HY-Y0850U5

*PVA (Mw 27000, 98-99% hydrolyzed, ～600 polymerization)* Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ～600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ～600 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 27000, 98-99% hydrolyzed, ～600 polymerization) is a polyvinyl alcohol with molecular weight of 27000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 27000, 98-99% hydrolyzed, ～600 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .

HY-Y0850U7

*PVA (Mw 195000, 98-99% hydrolyzed, ～4300 polymerization)* Polyvinyl alcohol (Mw 195000, 98-99% hydrolyzed, ～4300 polymerization); Poly(Ethenol) (Mw 195000, 98-99% hydrolyzed, ～4300 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 195000, 98-99% hydrolyzed, ～4300 polymerization) is a polyvinyl alcohol with molecular weight of 195000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 195000, 98-99% hydrolyzed, ～4300 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .

HY-Y0850U8

*PVA (Mw 47000, 98-99% hydrolyzed, ～1000 polymerization)* Polyvinyl alcohol (Mw 47000, 98-99% hydrolyzed, ～1000 polymerization); Poly(Ethenol) (Mw 47000, 98-99% hydrolyzed, ～1000 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 47000, 98-99% hydrolyzed, ～1000 polymerization) is a polyvinyl alcohol with molecular weight of 47000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 47000, 98-99% hydrolyzed, ～1000 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .

HY-Y0850U9

*PVA (Mw 67000, 87-89% hydrolyzed, ～1400 polymerization)* Polyvinyl alcohol (Mw 67000, 87-89% hydrolyzed, ～1400 polymerization); Poly(Ethenol) (Mw 67000, 87-89% hydrolyzed, ～1400 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 67000, 87-89% hydrolyzed, ～1400 polymerization) is a polyvinyl alcohol with molecular weight of 67000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 67000, 87-89% hydrolyzed, ～1400 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .

HY-155841

*Tubulin polymerization-IN-46*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/Tubulin inhibitor that inhibits tubulin polymerization and induces apoptosis. Tubulin polymerization-IN-46 inhibits mitosis and arrests MCF-7 cells in the G2/M phase. Tubulin polymerization-IN-46 has anti-proliferative activity against MCF-7 breast cancer cells with an IC₅₀ of 10 nM .

HY-155362

*Tubulin polymerization-IN-56*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-56 (compound 8l), an indazole derivative, is a potent tubulin polymerization inhibitor through interacting with the colchicine site, resulting in cell cycle arrest and cellular apoptosis. polymerization-IN-56 reduces cell migration and leads to more potent inhibition of tumor growth in vivo .

HY-149016

*Tubulin polymerization-IN-25*	Microtubule/Tubulin Farnesyl Transferase	Cancer
Tubulin polymerization-IN-25 (compound 17f) is a dual inhibitor of tubulin polymerization and farnesyl transferase (FTase) with IC₅₀s of 1.11 μM and 0.39 μM, respectively. Tubulin polymerization-IN-25 displays cytotoxicity and excellent antitumor activity .

HY-155359

*Tubulin polymerization-IN-55*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-55 is a potent inhibitor of Tubulin Polymerization. Tubulin polymerization-IN-55 has antiproliferative activity against A549, K562, HepG2, MDA-MB-231 and HFL-1 with IC₅₀ s of 8, 3, 9, 24 and 62 nM, respectively .

HY-143247

*Tubulin polymerization-IN-2*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-2 is a potent anticancer agent targeting to β-tubulin with an IC₅₀ value of 0.92 μM. Tubulin polymerization-IN-2 shows promising activity against various leukemia, non-small lung, renal, prostate, and breast cancer cell lines .

HY-151394

*Tubulin polymerization-IN-33*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-33 is an inhibitor of [1,2]oxazoloisoindoles tubulin polymerization, exhibits high antiproliferative activity against the NCI panel .

HY-151395

*Tubulin polymerization-IN-34*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-34 is an inhibitor of [1,2]oxazoloisoindoles tubulin polymerization, demonstrates high selectivity against marginal zone lymphoma VL51 cell line .

HY-151396

*Tubulin polymerization-IN-35*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-35 is an inhibitor of [1,2]oxazoloisoindoles tubulin polymerization, demonstrates high selectivity against marginal zone lymphoma VL51 cell line .

HY-151393

*Tubulin polymerization-IN-32*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-32 is a tubulin polymerization inhibitor. Tubulin polymerization-IN-32 inhibits cancer cell proliferation. Tubulin polymerization-IN-32 can be used in the research of cancers like lymphomas .

HY-168565

*Tubulin polymerization-IN-70*	Apoptosis Microtubule/Tubulin Reactive Oxygen Species	Cancer
Tubulin polymerization-IN-70 (compound Q19) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-70 shows antiproliferative activity. Tubulin polymerization-IN-70 target the colchicine binding site of tubulin and inhibited tubulin polymerization. Tubulin polymerization-IN-70 induces apoptosis and cell cycle arrest at G2/M phase. Tubulin polymerization-IN-70 induces mitochondrial membrane potential decrease and increases the levels of reactive oxygen species (ROS). Tubulin polymerization-IN-70 shows antiangiogenic and anticancer activity .

HY-163664

*Tubulin polymerization-IN-63*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-63 (compound 6) is a tubulin polymerization inhibitor. The IC₅₀ value of Tubulin polymerization-IN-63 for MES-SA cells is 0.29 μM. Tubulin polymerization-IN-63 can be used in cancer research .

HY-151397

*Tubulin polymerization-IN-36*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-36 is a tubulin polymerization inhibitor (IC₅₀: 2.8 μΜ). Tubulin polymerization-IN-36 binds to the colchicine site of tubulin and inhibits colchicine binding. Tubulin polymerization-IN-36 can be used in the research of cancers, such as lymphomas .

HY-151398

*Tubulin polymerization-IN-37*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-37 is a tubulin polymerization inhibitor (IC₅₀: 2.3 μΜ). Tubulin polymerization-IN-37 binds to the colchicine site of tubulin and inhibits colchicine binding. Tubulin polymerization-IN-37 can be used in the research of cancers, such as lymphomas .

HY-101989

*Tubulin polymerization-IN-24*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-24 (compound HMBA) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-24 inhibits MCF-7 cells proliferation. Tubulin polymerization-IN-24 induces apoptosis and cell cycle arrest at G2/M phase. Tubulin polymerization-IN-24 increase the GTP hydrolysis rate and inhibits microtubule assembly .

HY-144786

*Tubulin polymerization-IN-4*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-4 is a potent tubulin polymerization inhibitor with IC₅₀ value of 4.6 μM. Tubulin polymerization-IN-4 can disrupt tubulin polymerization and vasculature, arrest the cell cycle at the G2/M phase, induce apoptosis, and suppress clonogenesis and migration in HeLa cells. Tubulin polymerization-IN-4 can be used for researching cervical cancer .

HY-157543

*Tubulin polymerization-IN-59*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-59 ((R)-9k) is a potent inhibitor of colchicine binding site inhibitor (CBSI). Tubulin polymerization-IN-59 inhibits tubulin polymerization .

HY-147981

*Tubulin polymerization-IN-31*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-31 (Compound 4c) is a tubulin polymerization inhibitor with an IC₅₀ of 3.64 μM. Tubulin polymerization-IN-31 induces cancer cell apoptosis and shows antitumor activity .

HY-155963

*Tubulin polymerization-IN-48*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-48 (Compound 4k) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-48 has a moderate effect on disruption of the microtubule network. Tubulin polymerization-IN-48 inhibits neuroblastoma cancer cell proliferation, with IC₅₀s of 79 and 165 nM for Chp-134 and Kelly cell line .

HY-147848

*Tubulin polymerization-IN-27*	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-27 (compound 5j) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-27 can arrest cell cycle at G2/M phase and induce apoptosis .

HY-146817

*Tubulin polymerization-IN-11*	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-11 is a potent tubulin polymerization inhibitor with an IC₅₀ value of 3.4 µM. Tubulin polymerization-IN-11 shows antiproliferative activity. Tubulin polymerization-IN-11 induces Apoptosis and cell cycle arrest at G2/M phase. Tubulin polymerization-IN-11 decreases the expression of cyclin B1, p-cdc2, and Bcl-2 protein levels and increases the expression of cleaved PARP .

HY-146505

*Tubulin polymerization-IN-6*	Microtubule/Tubulin Apoptosis Reactive Oxygen Species	Cancer
Tubulin polymerization-IN-6 (compound 5f) is a potent tubulin polymerization inhibitor, with an IC₅₀ of 1.09 μM. Tubulin polymerization-IN-6 inhibits cell migration and tube formation and contributes to the anti-angiogenesis. Tubulin polymerization-IN-6 can greatly inhibit tumor growth on HT29 xenograft Balb/c nude mice .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W000800

cis,cis-Muconic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
cis,cis-Muconic acid, a metabolic intermediate of Klebsiella pneumonia, can be converted to adipic acid and terephthalic acid, which are important monomers of synthetic polymers. cis,cis-Muconic acid is also a biochemical material that can be used for the production of various plastics and polymers and is particularly gaining attention as an adipic acid precursor for the synthesis of nylon-6,6 .

HY-N2567

(±)-Decursinol	Infection other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields	Bacterial
(±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC₅₀ of 102 μM .

HY-Y0932

Isophorone	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Biochemical Assay Reagents
Isophorone, an α,β-unsaturated cyclic ketone, is used as a precursor to polymers .

HY-N6682

Cytochalasin D 45+ Cited Publications Zygosporin A; NSC 209835	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Arp2/3 Complex Antibiotic YAP
Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap .

HY-Y0520

Itaconic acid 1 Publications Verification Methylenesuccinic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Ferroptosis
Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .

HY-N1131

Triacetonamine 1 Publications Verification 2,2,6,6-Tetramethyl-4-piperidone	Tribulus terrester Linn. Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Zygophyllaceae Source classification Other Diseases Plants Disease Research Fields	Biochemical Assay Reagents
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats .

HY-127042

6,7-Epoxy-latrunculin A 6,7-Epoxy-LAT-A	Structural Classification Natural Products Microorganisms Source classification	Arp2/3 Complex
6,7-Epoxy-latrunculin A can be isolated from the Red Sea sponge Negombata magnifica and is initially identified as an inhibitor of actin polymerization by its morphological effects .

HY-N1915

Cellohexaose	Structural Classification Natural Products Polysaccharides Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
Cellohexaose is a glucose polymer with two or more glucose monomers produced from the breakdown of cellulose, consisting of a condensation of beta (1-4) linked D-glucose monomers .

HY-N9842

Violanone	Infection Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Isoflavones	Microtubule/Tubulin
Violanone, an isoflavanone compound, can inhibit tubulin polymerization. Violanone also exhibits larvicidal activity against A. aegypti .

HY-Y0932R

Isophorone (Standard)	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Biochemical Assay Reagents
Isophorone (Standard) is the analytical standard of Isophorone. This product is intended for research and analytical applications. Isophorone, an α,β-unsaturated cyclic ketone, is used as a precursor to polymers .

HY-N1131B

Triacetonamine monohydrate 2,2,6,6-Tetramethyl-4-piperidone monohydrate	Alkaloids Piperidine Alkaloids Structural Classification other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Biochemical Assay Reagents
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats .

HY-101848

Latrunculin B	Infection Animals Classification of Application Fields Marine natural products Sponge Disease Research Fields	Fungal
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .

HY-126989

19-O-Acetylchaetoglobosin A	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	Arp2/3 Complex
19-O-Acetylchaetoglobosin A, a cytochalasan alkaloid, is a fungal metabolite originally isolated from C. globosum that has actin polymerization inhibitory and cytotoxic activities. 19-O-Acetylchaetoglobosin A is cytotoxic to HeLa cervical cancer cells .

HY-Y0335

1,3-Dihydroxyacetone Dihydroxyacetone	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .

HY-P0027

Jasplakinolide 5 Publications Verification	Structural Classification Antifungal Classification of Application Fields Marine natural products Source classification Disease Research Other Antibiotics Infection Monophenols Animals Antibiotics Cyclopeptides Phenols Sponge Anticancer Disease Research Fields	Arp2/3 Complex Fungal
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a K_d of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .

HY-Y0335R

1,3-Dihydroxyacetone (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
1,3-Dihydroxyacetone (Standard) is the analytical standard of 1,3-Dihydroxyacetone. This product is intended for research and analytical applications. 1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .

HY-125527

Resolvin D1 RvD1	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	Endogenous Metabolite
Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .

HY-15580

Dolastatin 10 DLS 10; NSC 376128	Structural Classification Natural Products Classification of Application Fields Source classification Marine natural products Other marine organisms Disease Research Fields Cancer	Microtubule/Tubulin ADC Cytotoxin
Dolastatin 10 (DLS 10) is a potent antimitotic peptide that inhibits tubulin polymerization.

HY-N11766

Calythropsin	Structural Classification Faramea salicifolia Presi Source classification Rubiaceae Phenols Polyphenols Plants	Others
Calythropsin is a cytotoxic chalcone, with weak effect on mitosis, and presumably also on tubulin polymerization .

HY-107378

L-Valyl-L-phenylalanine Valylphenylalanine; H-VAL-PHE-OH	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
L-Valyl-L-phenylalanine (Valylphenylalanine; H-VAL-PHE-OH) has been reported as biocompatible polymer.

HY-Y0479

L-Lactic acid 5 Publications Verification (S)-2-Hydroxypropanoic acid	Structural Classification Classification of Application Fields Source classification Endocrine diseases Endogenous metabolite Infection Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder	Bacterial Endogenous Metabolite Antibiotic
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-13503

Epothilone A Epo A	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Cancer	Microtubule/Tubulin Apoptosis
Epothilone A is a competitive inhibitor of the binding of [ ³H] paclitaxel to tubulin polymers, with a K_i of 0.6-1.4 μM.

HY-N2415

Podophyllotoxone 1 Publications Verification	Structural Classification Classification of Application Fields Source classification Lignans Dysosma versipellis (Hance) M. Cheng ex Ying Phenylpropanoids Plants Berberidaceae Disease Research Fields Cancer	Microtubule/Tubulin
Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization .

HY-N3950

Glochidiol	Triterpenes Structural Classification Phyllanthaceae Glochidion eriocarpum Champ. ex Benth. Terpenoids Source classification Plants	Microtubule/Tubulin
Glochidiol is an orally active tubulin polymerization inhibitor with an IC₅₀ of 2.76 μM. Glochidiol shows anti-cancer activity .

HY-N6070

Ricinoleic acid (purity≥85%)	Structural Classification Classification of Application Fields Ricinus communis L. Ketones, Aldehydes, Acids Source classification Other Diseases Euphorbiaceae Plants Disease Research Fields	Biochemical Assay Reagents
Ricinoleic acid (purity≥85%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings .

HY-142013

Blestriarene B (-)-Blestriarene B	Bletilla striata (Thunb. ex Murray) Rchb. f. Structural Classification Natural Products Orchidaceae Source classification Plants	Others
Blestriarene B ((-)-Blestriarene B) a stilbenoid isolated by the guidance of inhibitory effect of tubulin polymerization from the tubers of Bletilla striata (Orchidaceae) .

HY-20584

10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyltaxol; 10-Deacetylpaclitaxel 7-Xyloside; 10-Deacetyltaxol 7-Xyloside	Classification of Application Fields Terpenoids Source classification Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.	Microtubule/Tubulin ADC Cytotoxin
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel (a microtubule stabilizing agent; enhances tubulin polymerization) derivative with improved pharmacological features.

HY-N8287

Oxaline	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Microtubule/Tubulin
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-N8039

Ganoderic acid T-Q Ganodermic acid T-Q	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Microtubule/Tubulin
Ganoderic acid T-Q (Ganodermic acid T-Q) (compound 1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid T-Q stimulates tubulin polymerization .

HY-N8745

α-Peltatin	Structural Classification Podophyllum peltatum L. Source classification Lignans Phenylpropanoids Plants Berberidaceae	Fungal
α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

HY-16929

Latrunculin A 5+ Cited Publications LAT-A	Structural Classification Macrolide Antibiotics Animals Classification of Application Fields Antibiotics Marine natural products Source classification Other Diseases Sponge Disease Research Anticancer Disease Research Fields	Arp2/3 Complex
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K_ds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .

HY-B0015

Paclitaxel Maximum Cited Publications 231 Publications Verification	Structural Classification Classification of Application Fields Terpenoids Taxaceae Diterpenoids Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	Microtubule/Tubulin ADC Cytotoxin Apoptosis Autophagy
Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .

HY-111830

Lignin 1 Publications Verification Lignine	Structural Classification other families Classification of Application Fields Source classification Lignans Other Diseases Phenylpropanoids Plants Disease Research Fields	Others
Lignin (Lignine) is a natural complex biopolymer with biodegradable and biocompatible. Lignin is the main component of plant cell walls and is a renewable aromatic polymer. Lignin has strongly antioxidant activity .

HY-13503R

Epothilone A (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Disease Research Anticancer	Microtubule/Tubulin Apoptosis
Epothilone A (Standard) is the analytical standard of Epothilone A. This product is intended for research and analytical applications. Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.

HY-Y0479R

L-Lactic acid (Standard)	Infection Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder	Bacterial Endogenous Metabolite Antibiotic
L-Lactic acid (Standard) is the analytical standard of L-Lactic acid. This product is intended for research and analytical applications. L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-19474

Maytansinol Ansamitocin P-0	Alkaloids Microorganisms Other Alkaloids Source classification Disease Research Fields Cancer	Microtubule/Tubulin ADC Cytotoxin Apoptosis
Maytansinol (Ansamitocin P-0) is a derivative of Maytansine. Maytansinol can inhibit tubulin polymerization and induce apoptosis. Maytansinol has antitumor activity. Maytansinol can be used in cancer drug research .

HY-16928

Cytochalasin B 25+ Cited Publications Phomin	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	Arp2/3 Complex
Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with K_d value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.

HY-32004

Coumalic acid	Structural Classification Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Smilacis Glabrae Rhizoma Plants Disease Research Fields	Biochemical Assay Reagents
Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity .

HY-132188

Manganese peroxidase	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization .

HY-Y1004

1-Decanol Decyl alcohol	Microorganisms Source classification	Biochemical Assay Reagents
1-Decanol is used in the production of lubricants, surfactants, plasticizers and solvents. It has also been used to study the thermal properties of polymeric monolithic stationary phases and to enhance homopolyglycine acceptor function. Used in cosmetics, daily flavors, and food flavors.

HY-N7428

1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is an endogenous metabolite. The imprinted polymer P-1 shows affinity for 1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol .

HY-B0015R

Paclitaxel (Standard)	Structural Classification Terpenoids Taxaceae Diterpenoids Plants Taxus chinensis (Pilger) Rehd.	Microtubule/Tubulin ADC Cytotoxin Apoptosis Autophagy
Paclitaxel (Standard) is the analytical standard of Paclitaxel. This product is intended for research and analytical applications. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .

HY-N6070R

Ricinoleic acid (purity≥85%) (Standard)	Structural Classification Ricinus communis L. Ketones, Aldehydes, Acids Source classification Euphorbiaceae Plants	Biochemical Assay Reagents
Ricinoleic acid (purity≥85%) (Standard) is the analytical standard of Ricinoleic acid (purity≥85%). This product is intended for research and analytical applications. Ricinoleic acid (purity≥85%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings .

HY-N6773

Cytochalasin A	Infection Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields	HIV Protease Fungal
Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC₅₀=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives .

HY-138962

κ-Carrageenan K-Carrageenan Karra Type	Structural Classification Natural Products other families Classification of Application Fields Source classification Red seaweeds Plants Inflammation/Immunology Disease Research Fields Cancer	Apoptosis
κ-Carrageenan is a natural polymer which predominantly available in red seaweeds. κ-Carrageenan is an effective agent carrier to deliver curcumin in cancer cells and to induce apoptosis. κ-carrageenan serves as a potential inflammatory agent that magnifies existing intestinal inflammation .

HY-N0282

Demecolcine 3 Publications Verification	Alkaloids Structural Classification other families Classification of Application Fields Other Alkaloids Source classification Plants Inflammation/Immunology Disease Research Fields	Microtubule/Tubulin Apoptosis
Demecolcine is a potent mitotic inhibitor with an IC₅₀ value of 2.4 μM for inhibition of tubulin polymerization. Colcemid (Demecolcine) can interact with tubulin dimers to induce anti-mitotic action and inhibit microtubule growth. Colcemid (Demecolcine) can be used for inflammatory disorders and cancer research .

HY-N6613

Polygalacturonic acid Galacturonic acid polymer	Infection Structural Classification Natural Products Polysaccharides Classification of Application Fields Malus pumila Mill. Rosaceae Plants Inflammation/Immunology Disease Research Fields Saccharides	Others
Polygalacturonic acid (Galacturonic acid polymer) is transparent colloid, is a major component of the cell wall. Polygalacturonic acid can be used to prepare silver nanoparticles (AgNPs), as an antioxidant and anti-inflammatory that protect cells from destructive effect of elevated ROS and accelerate wound healing. Polygalacturonic acid nanoparticles also displays anti-bacterial activity .

HY-N6834

Fructo-oligosaccharide DP10/GF9	Structural Classification Polysaccharides Classification of Application Fields Source classification Other Diseases Rubiaceae Plants Morinda officinalis How Disease Research Fields Saccharides	Others
Fructo-oligosaccharide DP10/GF9 belongs to fructooligosaccharides (FOS) with degree of polymerization (DP=10). Fructo-oligosaccharides (FOS) are composed of 9 fructose units linked by (2→1)-β-glycosidic bonds and having a single D-glucosyl unit at the non-reducing end .

HY-N6835

Fructo-oligosaccharide DP9/GF8	Polysaccharides Classification of Application Fields Gramineae Source classification Other Diseases Plants Disease Research Fields Saccharum officinarum Saccharides	Others
Fructo-oligosaccharide DP9/GF8 belongs to fructooligosaccharides (FOS) with degree of polymerization (DP=9). Fructo-oligosaccharides (FOS) are composed of 8 fructose units linked by (2→1)-β-glycosidic bonds and having a single D-glucosyl unit at the non-reducing end .

HY-N6836

Fructo-oligosaccharide DP8/GF7	Polysaccharides Classification of Application Fields Gramineae Source classification Other Diseases Plants Disease Research Fields Saccharum officinarum Saccharides	Others
Fructo-oligosaccharide DP8/GF7 belongs to fructooligosaccharides (FOS) with degree of polymerization (DP=8). Fructo-oligosaccharides (FOS) are composed of 7 fructose units linked by (2→1)-β-glycosidic bonds and having a single D-glucosyl unit at the non-reducing end .

Cat. No.	Product Name	Chemical Structure

HY-Y0520S

Itaconic acid-13C5
Itaconic acid- ¹³C₅ is the ¹³C labeled Itaconic acid. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors[1][2].

HY-116852S

Thiocolchicine-d3

Thiocolchicine-d₃ is deuterium labeled Thiocolchicine. Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 µM) and competitively binds to tubulin with a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis[1][2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.

HY-Y0932S

Isophorone-d5
Isophorone-d₅ is the deuterium labeled Isophorone. Isophorone, an α,β-unsaturated cyclic ketone, is used as a precursor to polymers[1].

HY-Y0932S1

Isophorone-d8
Isophorone-d₈ is the deuterium labeled Isophorone[1]. Isophorone, an α,β-unsaturated cyclic ketone, is used as a precursor to polymers[2].

HY-W728761

Voxelotor-d7
Voxelotor-d7 is the deuterium labeled Voxelotor (HY-18681). Voxelotor is a potent inhibitor of haemoglobin S (HbS) polymerization .

HY-Y0479S3

L-Lactic acid-2-13C1
L-Lactic acid-2- ¹³C₁ is the ¹³C-labeled L-Lactic acid. L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-B0015S1

Paclitaxel-d5 (benzoyloxy)
Paclitaxel-d₅ (benzoyloxy) is the deuterium labeled Paclitaxel. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy[1][2].

HY-16569S

Colchicine-d6
Colchicine-d₆ is the deuterium labeled Colchicine. Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM[1][2][3]. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs)[4].

HY-16569S1

Colchicine-d3
Colchicine-d₃ is the deuterium labeled Colchicine. Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM[1][2][3]. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs)[4].

HY-107116S

MAP4343-d4
MAP4343-d₄ is the deuterium labeled MAP4343. MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents[1][2][3].

HY-125527S

Resolvin D1-d5

Resolvin D1-d₅ is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages[1][2].

HY-W011188S

Glycidyl stearate-d5

Glycidyl stearate-d₅ is a deuterium labeled Glycidyl stearate (HY-W011188). Oxiran-2-ylmethyl stearate is a compound belonging to the class of esters. It contains reactive oxirane or epoxy groups that give the molecule its unique properties. Oxiran-2-ylmethyl stearate is derived from stearic acid and epichlorohydrin, which are naturally occurring substances. Glycidyl stearate is commonly used in various industrial applications such as the production of coatings, adhesives and surfactants. It can also be used as a crosslinking agent in the manufacture of polymers and resins.

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