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NF-kB,bioactive peptide,reduce fat accumulation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fat Mass and Obesity-associated Protein (FTO) (15) NF-κB (16) 5-HT Receptor (5) Acyltransferase (4) ADC Cytotoxin (1) Adenosine Deaminase (2) Adenosine Receptor (7) Adrenergic Receptor (13) Akt (9) Aldehyde Dehydrogenase (ALDH) (2) Aldose Reductase (3) Amino Acid Derivatives (1) Aminopeptidase (2) AMPK (5) Amyloid-β (4) Androgen Receptor (1) Angiotensin-converting Enzyme (ACE) (3) Antibiotic (6) Apoptosis (71) Aryl Hydrocarbon Receptor (1) Atg8/LC3 (3) Aurora Kinase (3) Autophagy (32) Bacterial (22) Bcl-2 Family (5) BCRP (1) Biochemical Assay Reagents (19) Bombesin Receptor (1) c-Met/HGFR (1) Calcium Channel (3) Cannabinoid Receptor (5) Caspase (9) Cathepsin (1) CCR (1) CDK (1) Ceramidase (3) CFTR (2) CGRP Receptor (2) Chloride Channel (2) Cholinesterase (ChE) (5) COX (4) CRFR (1) Cytochrome P450 (8) Disulfidptosis (1) DNA/RNA Synthesis (1) Dopamine Receptor (2) Drug Metabolite (1) Drug-Linker Conjugates for ADC (1) DYRK (1) E1/E2/E3 Enzyme (3) EGFR (1) Endogenous Metabolite (131) Epigenetic Reader Domain (1) ERK (6) Estrogen Receptor/ERR (7) FAP (1) FATP (1) Fatty Acid Synthase (FASN) (1) Ferroptosis (13) Fluorescent Dye (9) Fungal (25) G protein-coupled Bile Acid Receptor 1 (1) G Protein-coupled Receptor Kinase (GRK) (1) GABA Receptor (1) Gap Junction Protein (8) GCGR (2) GHSR (2) GLP Receptor (4) Glucocorticoid Receptor (4) Glucokinase (2) GLUT (1) Glutaminase (2) Glutathione Peroxidase (4) GnRH Receptor (1) GPR52 (1) GPR84 (1) GSK-3 (1) Guanylate Cyclase (2) HBV (1) HCV (1) HDAC (16) Hedgehog (3) HIF/HIF Prolyl-Hydroxylase (10) Histamine Receptor (1) Histone Acetyltransferase (1) Histone Demethylase (1) Histone Methyltransferase (1) HIV (10) HMG-CoA Reductase (HMGCR) (2) HPPD (2) HSP (5) ICMT (2) IGF-1R (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (5) Insulin Receptor (2) Interleukin Related (4) IRE1 (1) Isotope-Labeled Compounds (24) JAK (2) JNK (2) Keap1-Nrf2 (4) Ketohexokinase (1) Lactate Dehydrogenase (1) LDLR (1) Leukotriene Receptor (2) Ligands for E3 Ligase (1) Lipase (1) Liposome (2) Lipoxygenase (2) LPL Receptor (1) LXR (3) mAChR (3) MCHR1 (GPR24) (2) MDM-2/p53 (7) MetAP (2) mGluR (6) Microtubule/Tubulin (2) Mitochondrial Metabolism (7) Mitophagy (5) MMP (3) Monoamine Oxidase (1) Monoamine Transporter (1) mTOR (2) Necroptosis (3) NO Synthase (3) NOD-like Receptor (NLR) (5) Notch (5) Nuclear Hormone Receptor 4A/NR4A (1) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (2) Organoid (4) Oxidative Phosphorylation (1) P-glycoprotein (6) P2Y Receptor (2) p38 MAPK (3) p62 (3) PAK (1) Parasite (6) PARP (6) PCSK9 (3) PD-1/PD-L1 (3) PERK (1) PGC-1α (2) PGE synthase (2) Phosphatase (1) Phosphodiesterase (PDE) (2) Photosystem II (1) PI3K (8) PINK1/Parkin (1) PKA (4) PKC (2) Potassium Channel (3) PPAR (15) Prostaglandin Receptor (4) PROTACs (5) Protease Activated Receptor (PAR) (1) Proteasome (2) Pyroptosis (1) Radionuclide-Drug Conjugates (RDCs) (1) Raf (1) RAR/RXR (1) Ras (3) Reactive Oxygen Species (39) RIP kinase (1) ROS Kinase (2) Ser/Thr Protease (1) SF3B1 (1) Sirtuin (6) Small Interfering RNA (siRNA) (6) Smo (4) SOD (4) Sodium Channel (2) Src (1) STAT (2) Stearoyl-CoA Desaturase (SCD) (2) Tau Protein (1) TGF-beta/Smad (1) TGF-β Receptor (1) Thyroid Hormone Receptor (6) TMV (1) TNF Receptor (7) Toll-like Receptor (TLR) (2) TRP Channel (1) TrxR (1) Tyrosinase (2) Vasopressin Receptor (1) VDAC (1) VEGFR (2) Wnt (5) Xanthine Oxidase (2) α-synuclein (4) β-catenin (3)
By Research Areas:	Cancer (201) Cardiovascular Disease (54) Endocrinology (37) Infection (72) Inflammation/Immunology (99) Metabolic Disease (211) Neurological Disease (101)
Click Chemistry:	Alkynes (3)
Oligonucleotides:	Nucleosides and their Analogs (1) Pre-designed siRNA Sets (4) Emulsifiers (2) Phospholipids (1) Cholesterol (1) siRNAs (6)

661

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

135

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: NF-κB Fat Mass and Obesity-associated Protein (FTO)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-134577

Clorprenaline	Adrenergic Receptor	Endocrinology
Clorprenaline is a potent agonist of β2-adrenergic. Clorprenaline promotes animal muscular mass growth and decreases fat accumulation. Clorprenaline is a potential new lean meat-boosting feed additive .

HY-N7515

Pinocembrin chalcone 2',4',6'-Trihydroxychalcone	Bacterial AMPK	Infection Metabolic Disease Inflammation/Immunology
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle FAO and reduces fat accumulation in the liver and skeletal muscles in high-fat diet-induced (HFD) diabetic mice. Pinocembrin chalcone is promising for research of gastric ulcers and diabetes .

HY-P5275

Tripeptide-41 CG-Lipoxyn	NF-κB	Metabolic Disease
Tripeptide-41(CG-Lipoxyn)isa bioactive peptide withreduce fat accumulationeffect and has been reported used as a cosmetic ingredient .

HY-N10755

(+)-ε-Viniferin	PGE synthase	Metabolic Disease Inflammation/Immunology
(+)-ε-Viniferin is a stilbenes compound with PGE2 inhibition effect, and is an orally active anti-inflammatory agent. ε-viniferin is also able to reduce fat accumulation, thus can be used for research of inflammation or obesity .

HY-134577R

Clorprenaline (Standard)	Adrenergic Receptor	Endocrinology
Clorprenaline (Standard) is the analytical standard of Clorprenaline. This product is intended for research and analytical applications. Clorprenaline is a potent agonist of β2-adrenergic. Clorprenaline promotes animal muscular mass growth and decreases fat accumulation. Clorprenaline is a potential new lean meat-boosting feed additive .

HY-118634

trans-Resveratrol-4'-O-D-Glucuronide R-4G	FATP	Metabolic Disease
Trans-Resveratrol-4'-O-D-Glucuronide (R-4G) is a metabolite of resveratrol with anti-fat accumulation property, and can be used for metabolic research .

HY-RS04760

FAT1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FAT1 Human Pre-designed siRNA Set A contains three designed siRNAs for FAT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FAT1 Human Pre-designed siRNA Set A FAT1 Human Pre-designed siRNA Set A

HY-RS04761

FAT2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FAT2 Human Pre-designed siRNA Set A contains three designed siRNAs for FAT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FAT2 Human Pre-designed siRNA Set A FAT2 Human Pre-designed siRNA Set A

HY-RS04762

FAT3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FAT3 Human Pre-designed siRNA Set A contains three designed siRNAs for FAT3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FAT3 Human Pre-designed siRNA Set A FAT3 Human Pre-designed siRNA Set A

HY-RS04763

FAT4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FAT4 Human Pre-designed siRNA Set A contains three designed siRNAs for FAT4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FAT4 Human Pre-designed siRNA Set A FAT4 Human Pre-designed siRNA Set A

HY-P1067A

Enterostatin(human,mouse,rat) TFA	Endogenous Metabolite	Metabolic Disease
Enterostatin (human,mouse,rat) TFA is a pentapeptide mainly formed in the intestine by the cleavage of secreted pancreatic procolipase. Enterostatin selectively reduces fat intake, bodyweight, and body fat in vivo .

HY-161985

PPARγ-IN-3	PPAR	Metabolic Disease
PPARγ-IN-3 (compound 9ga) is a potent and orally active PPARγ inhibitor. PPARγ-IN-3 reduces triglyceride (TG) accumulation with low cytotoxicity. PPARγ-IN-3 preventes the excessive growth of body weight and lessened fat mass as well as liver mass, decreases lipid accumulation in the liver and blood. PPARγ-IN-3 has the potential for the research of diet-induced obesity .

HY-P3704

Enterostatin (rat)	Endogenous Metabolite	Metabolic Disease
Enterostatin (rat), an orally active activation peptide of procolipase, selectively reduces fat intake. Enterostatin (rat) reduces serum cholesterol levels by way of a CCK1 receptor-dependent mechanism .

HY-W588293

3-Methylthymidine	Fat Mass and Obesity-associated Protein (FTO)	Others
3-Methylthymidine can be used to detect fat mass and obesity-associated protein (FTO) activity .

HY-101082

N6,2′-O-Dimethyladenosine	Fat Mass and Obesity-associated Protein (FTO)	Metabolic Disease
N6,2′-O-Dimethyladenosine, a substrate of fat mass and obesity-associated gene (FTO), is a reversible modification widely occurred on varied RNA molecules. N6,2′-O-Dimethyladenosine can regulate obesity .

HY-114611

BDM44768	IRE1	Metabolic Disease
BDM44768 is an inhibitior of IDE. BDM44768 exacerbates ER stress-induced IRE1 activation and promotes lipid accumulation in hepatocytes. BDM44768 potentiates activation of the IRE1 pathway in the liver and exacerbates liver lipid accumulation in an acute mice model of ER stress .

HY-133180

YW1128	Wnt β-catenin	Metabolic Disease
YW1128 (compound 3a) is a potent Wnt/β-Catenin inhibitor. YW1128 induces the proteasome degradation of β-catenin and subsequent inhibits the Wnt/β-catenin signaling in cells. YW1128 significantly decreases hepatic lipid accumulation. YW1128 improves glucose tolerance of high fat diet-fed mice without noticeable toxicity. YW1128 down regulates the genes involved in the glucose and fatty acid anabolism .

HY-13766

Timcodar VX-853	Others	Others
Timcodar is a macrolide agent, and studies have shown that during adipogenesis, timcodar can significantly inhibit fat accumulation, with an effect similar to that of rapamycin. However, unlike rapamycin, timcodar does not cause immunosuppression and glucose resistance. In addition, timcodar can effectively inhibit the adipogenic transcriptional regulators PPAR?? and C/EBP??, thereby inhibiting genes involved in fat accumulation. These studies lay the foundation for timcodar as a potential anti-obesity therapy, as obesity is becoming a global epidemic.

HY-N9535

tert-OMe-byakangelicin	Others	Metabolic Disease
tert-OMe-byakangelicin is a coumarin that can enhances the adrenaline-induced lipolytic effect and inhibits insulin-stimulated triglyceride synthesis from glucose in fat cells .

HY-135505

JTP-103237	Acyltransferase	Metabolic Disease
JTP-103237 is a MGAT2 inhibitor (IC₅₀: 0.019 μM and 6.423 μM for hMGAT2 and hMGAT3 respectively). JTP-103237 modulates fat absorption, decreases plasma glucose levels and prevents diet-induced obesity .

HY-D1353

LipidGreen 2	Fluorescent Dye	Others
LipidGreen 2 is a second generation small molecule probe for lipid imaging. LipidGreen 2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish .

HY-13626

Spisulosine ES-285	PKC	Cancer
Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation .

HY-W051298

Distearin Stearic diglyceride	Biochemical Assay Reagents	Metabolic Disease
Distearin is a diacylglycerol containing stearic acid at two positions. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils .

HY-143712

Allolithocholic acid	Endogenous Metabolite	Metabolic Disease
Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver .

HY-101607

KT-362	Calcium Channel	Cardiovascular Disease
KT-362 is an intracellular calcium antagonist. KT-362 can inhibit NE-induced contractions and IP accumulation in vivo experiments .

HY-161817

TGR5 agonist 5	G protein-coupled Bile Acid Receptor 1	Others
TGR5 agonist 5 (compound K91) is a potent agonist of TGR5, with EC₅₀s of 19 μM and 30 μM in CRE-Luciferase assay anf cAMP accumulation assay, respectively .

HY-147501

TRβ agonist 3	Thyroid Hormone Receptor	Metabolic Disease
TRβ agonist 3 (Compound 3) is a potent agonist of TRβ. TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 3 is a new potential TRβ-selective thyromimetics .

HY-147500

TRβ agonist 2	Thyroid Hormone Receptor	Metabolic Disease
TRβ agonist 2 (Compound 1) is a potent agonist of TRβ. TRβ agonist 2 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 2 is a new potential TRβ-selective thyromimetics .

HY-120872

AJS1669 free acid	Others	Metabolic Disease
AJS1669 free acid is a potent and orally available glycogen synthase (GS) activator. AJS1669 improves glucose metabolism and reduces body fat mass in mice[1].

HY-W018791

Bifendate DDB	HBV Autophagy Cytochrome P450 Atg8/LC3 p62 P-glycoprotein	Infection Cardiovascular Disease Cancer
Bifendate (DDB), extracted from Schisandrae chinensis, is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins (CYPs) and reverse P-gp-mediated multi-drug resistance (MDR) .

HY-138843

FTO-IN-1	Fat Mass and Obesity-associated Protein (FTO)	Metabolic Disease Cancer
FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC₅₀ of <1 μM. FTO-IN-1 can be used for the research of cancer .

HY-133100

5-ALA benzyl ester hydrochloride Benzyl-ALA hydrochloride	Endogenous Metabolite	Cancer
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .

HY-138843A

FTO-IN-1 TFA	Fat Mass and Obesity-associated Protein (FTO)	Metabolic Disease Cancer
FTO-IN-1 TFA is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC₅₀ of <1 μM. FTO-IN-1 TFA can be used for the research of cancer .

HY-P3579

*Gastric Inhibitory Peptide, porcine* GIP (1-42), porcine	Insulin Receptor	Endocrinology
Gastric Inhibitory Peptide, porcine is a glucose-dependent insulinotropic polypeptide, is a 42 amino acid intestinal hormone with effects on fat and glucose metabolism .

HY-Y1125

6-Methyluracil Pseudothymine	Endogenous Metabolite	Metabolic Disease
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo .

HY-113957

MPI_5a	HDAC	Cancer
MPI_5a is a potent and selective HDAC6 inhibitor (IC₅₀=36 nM). MPI_5a weakly inhibits other HDAC isoforms. MPI_5a inhibits acyl-tubulin accumulation in cells with an IC₅₀ value of 210 nM .

HY-125096

C108297	Glucocorticoid Receptor	Metabolic Disease Inflammation/Immunology
C108297 is a selective glucocorticoid receptor (GR) modulator (GR binding K_i 0.7 nM; GR reporter gene functional K_i 0.6 nM). C108297 attenuates obesity by reducing caloric intake and increasing lipolysis and fat oxidation, and in addition attenuates inflammation .

HY-156680

TNG-462	Histone Methyltransferase	Cancer
TNG-462 is an orally active and selective PRMT5 inhibitor with anti-tumor activity against methylthioadenosine phosphorylase (MTAP) deficiency and/or methylthioadenosine (MTA) accumulation cancers .

HY-135737

Dicaprylyl carbonate 1 Publications Verification	Others	Others
Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .

HY-131032

KI-7	Adenosine Receptor	Others
KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC₅₀=445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC₅₀s of 2390 nM and 2550 nM, respectively .

HY-50001

Nucleozin 5 Publications Verification	Influenza Virus	Infection
Nucleozin, a potent inhibitor of influenza A virus infection, induces the formation of nucleoprotein (NP) aggregates and antagonizes its nuclear accumulation, leading to cessation of viral replication. Nucleozin impedes influenza A virus replication in vitro with a nanomolar EC₅₀ .

HY-133707

β-Muricholic acid	Endogenous Metabolite	Metabolic Disease
β-Muricholic acid is a potent and orally active biliary cholesterol-desaturating agent. β-Muricholic acid prevents cholesterol gallstones. β-Muricholic acid inhibits lipid accumulation. β-Muricholic acid has the potential for the research of nonalcoholic fatty liver disease (NAFLD) .

HY-107420

AY 9944 3 Publications Verification	Others	Metabolic Disease
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme with an IC₅₀ of 13 nM. AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol .

HY-152199

AMPD2 inhibitor 2	Adenosine Deaminase	Metabolic Disease
AMPD2 inhibitor 2 (compound 21) is a potent AMP deaminase 2 (AMPD2) inhibitor with IC₅₀s of 0.1 μM and 0.28μM for hAMPD2 and mAMPD2, respectively. AMPD2 inhibitor 2 has the potential for evaluating the physiological role of AMPD2 in mice maintained on a high fat diet .

HY-131370B

Intralipid 20%	Others	Cancer
Intralipid 20% is a safe fat emulsion that can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response .

HY-149453

MCUF-651	Guanylate Cyclase	Cardiovascular Disease
MCUF-651 is an orally active guanylyl cyclase A receptor (GC-A) positive allosteric modulator (PAM) (K_D: 397 nM ). MCUF-651 binds to GC-A and selectively enhances the binding of atrial natriuretic peptide (ANP) to GC-A. MCUF-651 enhances ANP-mediated cGMP generation in human cardiac, renal, and fat cells. MCUF-651 inhibits cardiomyocyte hypertrophy .

HY-115319

CP-24879 hydrochloride 1 Publications Verification	Ferroptosis	Inflammation/Immunology
CP-24879 (hydrochloride) is a potent, selective and combined delta5D/delta6D inhibitor. CP-24879 (hydrochloride) can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 (hydrochloride) exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ω-3-treated hepatocytes, and can be used for non-alcoholic steatohepatitis research .

HY-P5815

GLP-1 (1-36) amide (human, rat) Glucagon-like Peptide 1 (1-36) amide (human, rat)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells .

HY-135507

NAS-181	5-HT Receptor	Neurological Disease
NAS-181 is a potent and selective rat 5-hydroxytryptamine1B (r5-HT1B) antagonist with an K_i value of 47 nM. NAS-181 increases the 5-HTP accumulation in rat brain regions .

HY-P5815A

GLP-1 (1-36) amide (human, rat) (TFA) Glucagon-like Peptide 1 (1-36) amide (human, rat) (TFA)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7515

Pinocembrin chalcone 2',4',6'-Trihydroxychalcone	Structural Classification Chalcones Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Bacterial AMPK
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle FAO and reduces fat accumulation in the liver and skeletal muscles in high-fat diet-induced (HFD) diabetic mice. Pinocembrin chalcone is promising for research of gastric ulcers and diabetes .

HY-13626

Spisulosine ES-285	Alkaloids Classification of Application Fields Animals Source classification Marine natural products Other marine organisms Disease Research Fields Cancer	PKC
Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation .

HY-143712

Allolithocholic acid	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver .

HY-133100

5-ALA benzyl ester hydrochloride Benzyl-ALA hydrochloride	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .

HY-Y1125

6-Methyluracil Pseudothymine	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo .

HY-135737

Dicaprylyl carbonate 1 Publications Verification	Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .

HY-133707

β-Muricholic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
β-Muricholic acid is a potent and orally active biliary cholesterol-desaturating agent. β-Muricholic acid prevents cholesterol gallstones. β-Muricholic acid inhibits lipid accumulation. β-Muricholic acid has the potential for the research of nonalcoholic fatty liver disease (NAFLD) .

HY-17462

Adrenosterone (+)-Adrenosterone	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Androgen Receptor Endogenous Metabolite
Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor. Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells .

HY-N10755

(+)-ε-Viniferin	Structural Classification Source classification Phenols Polyphenols Vitis sinocinerea W. T. Wang Plants Vitaceae	PGE synthase
(+)-ε-Viniferin is a stilbenes compound with PGE2 inhibition effect, and is an orally active anti-inflammatory agent. ε-viniferin is also able to reduce fat accumulation, thus can be used for research of inflammation or obesity .

HY-N9535

tert-OMe-byakangelicin	Structural Classification Classification of Application Fields Source classification Coumarins Metabolic Disease Phenylpropanoids Umbelliferae Helogyne apaloidea Nutt. Plants Disease Research Fields	Others
tert-OMe-byakangelicin is a coumarin that can enhances the adrenaline-induced lipolytic effect and inhibits insulin-stimulated triglyceride synthesis from glucose in fat cells .

HY-N8466

(-)-Lyoniresinol 9'-O-glucoside	Structural Classification Albizia julibrissin Durazz. Leguminosae Source classification Plants Saccharides Monosaccharides	Reactive Oxygen Species
(-)-Lyoniresinol 9'-O-glucoside is an inhibitor of ROS. (-)-Lyoniresinol 9'-O-glucoside reduces lipid accumulation and lipid metabolic disorders in FFAs-exposed HepG2 cells. (-)-Lyoniresinol 9'-O-glucoside inhibits high glucose-induced reactive oxygen species production .

HY-129143

Delphinidin-3-sambubioside chloride Dp3‐Sam chloride	Malvaceae Structural Classification Flavonoids Hibiscus sabdariffa Linn. Plants Other Flavonoids	Others
Delphinidin-3-sambubioside (Dp3‐Sam) chloride is an anthocyanin that has orally active anti-inflammatory activity. Delphinidin-3-sambubioside chloride inhibits LPS-induced inflammatory factors release. Delphinidin-3-sambubioside chloride also alleviates hepatic lipid accumulation in HFD rats. Delphinidin-3-sambubioside chloride can be isolated from Hibiscus sabdariffa L. .

HY-129143R

Delphinidin-3-sambubioside chloride (Standard)	Malvaceae Structural Classification Flavonoids Hibiscus sabdariffa Linn. Plants Other Flavonoids	Others
Delphinidin-3-sambubioside (chloride) (Standard) is the analytical standard of Delphinidin-3-sambubioside (chloride). This product is intended for research and analytical applications. Delphinidin-3-sambubioside (Dp3‐Sam) chloride is an anthocyanin that has orally active anti-inflammatory activity. Delphinidin-3-sambubioside chloride inhibits LPS-induced inflammatory factors release. Delphinidin-3-sambubioside chloride also alleviates hepatic lipid accumulation in HFD rats. Delphinidin-3-sambubioside chloride can be isolated from Hibiscus sabdariffa L. .

HY-B1131

Taurocholic acid sodium salt hydrate 10+ Cited Publications Sodium taurocholate hydrate; N-Choloyltaurine sodium salt hydrate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is a bile acid involved in the emulsification of fats.

HY-Y0781

Pyruvic acid 5+ Cited Publications Acetylformic acid	Structural Classification Classification of Application Fields Source classification Endocrine diseases Endogenous metabolite Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Other Diseases Nervous System Disorder Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-P1067

Enterostatin(human,mouse,rat)	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.

HY-N12440

Sarmenoside II	Structural Classification Source classification Crassulaceae Sedum sarmentosum Bunge Phenols Polyphenols Plants	Others
Sarmenoside II is a flavonol glycoside with activity that inhibits lipid accumulation. Sarmenoside II inhibits albumin-oleate-induced lipid accumulation in HepG2 cells by approximately 30% at 100 μM.

HY-113016

Elaidic acid 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent.

HY-N10063

Penispidin A	Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Others
Penispidin A inhibits hepatic lipid accumulation in HepG2 cells.

HY-B2219A

Calcium stearate 5+ Cited Publications	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Calcium stearate is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N2041

Myristic acid 3 Publications Verification	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite NF-κB Bacterial
Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

HY-N3686

D-Arabitol	Structural Classification Microorganisms Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in human.

HY-N7074

Lanolin	Structural Classification Natural Products Animals Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Bacterial
Lanolin is a yellow fat obtained from sheep's wool. Lanolin is used topically for sore, cracked nipples during breastfeeding .

HY-N0378

D-Mannitol 5+ Cited Publications Mannitol; Mannite	Structural Classification Natural Products Microorganisms other families Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Sweeteners Food Research	Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA
D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

HY-Y0781R

Pyruvic acid (Standard)	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder	Endogenous Metabolite
Pyruvic acid (Standard) is the analytical standard of Pyruvic acid. This product is intended for research and analytical applications. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-113152

Hypogeic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hypogeic acid can be isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters .

HY-124557

Mahanimbine	Structural Classification Alkaloids Classification of Application Fields Source classification Rutaceae Murraya koenigii (L.) Spreng Carbazole Alkaloids Plants Inflammation/Immunology Disease Research Fields Murraya exotica L. Mant. Indole Alkaloids	Others
Mahanimbine is an orally active alkaloid from Murraya koenigii. Mahanimbine inhibits progression of high-fat diet (HFD)-induced metabolic complications in mice .

HY-N2041R

Myristic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Myristicaceae Plants Myristica fragrans Houtt. Endogenous metabolite	Endogenous Metabolite NF-κB Bacterial
Myristic acid (Standard) is the analytical standard of Myristic acid. This product is intended for research and analytical applications. Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

HY-N0324

Cholic acid 5+ Cited Publications	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-N0324A

Cholic acid sodium 5+ Cited Publications Sodium cholate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active .

HY-129297

CMPF	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice .

HY-N10788

Pomonic acid	Triterpenes Structural Classification Terpenoids Verbenaceae Source classification Plants Lantana camaraLinn.	Acyltransferase
Pomonic acid is a triterpenoid that significantly inhibits cholesterol ester accumulation and suppresses the acyl coenzyme A:cholesterol acyltransferase (ACAT) activity .

HY-124141

Myristelaidic acid trans-9-Tetradecenoic acid	Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
Myristelaidic acid (trans-9-Tetradecenoic acid), a 14-carbon trans fatty acid, is the trans isomer of Myristoleic acid. Myristelaidic acid is found in most animal fats .

HY-N0324B

Cholic acid sodium hydrate	Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Cholic acid sodium hydrate is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid sodium hydrate facilitates fat absorption and cholesterol excretion. Cholic acid sodium hydrate is orally active .

HY-126400

Tocopherols	Structural Classification Natural Products Nitrariaceae Peganum harmala L. Source classification Plants	Endogenous Metabolite
Tocopherols are an important class of fat-soluble vitamins, the most common form of which is gamma-tocopherol, followed by beta-tocopherol and alpha-tocopherol .

HY-133823

11-Hexadecenoic acid C16:1 (cis-11/trans-11) fatty acid	Microorganisms Source classification	Endogenous Metabolite
11-Hexadecenoic acid is a monounsaturated fatty acid. 11-cis-Hexadecenoic acid and 11-trans-hexadecenoic acid have been found in ewe milk fat, and levels of each increase with dietary lipid supplementation of linseed, sunflower, olive, or fish oils. 11-trans-Hexadecenoic acid has also been found in intramuscular fat samples isolated from male and female foals. This product is a mixture of 11-cis- and 11-trans-hexadecenoic acids.

HY-B2219

Stearic acid 5+ Cited Publications	Structural Classification Immune System Disorder Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis
Stearic acid is a long-chain dietary saturated fatty acid that can significantly reduce visceral fat by inducing apoptosis of preadipocytes. Stearic acid can be used in the study of cardiovascular and metabolic diseases .

HY-113016R

Elaidic acid (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Elaidic acid (Standard) is the analytical standard of Elaidic acid. This product is intended for research and analytical applications. Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent.

HY-N4219

Saikosaponin B3	Triterpenes Terpenoids Source classification Plants Umbelliferae Carphephorus corymbosus (Nutt.) Torr. & A.Gray	Others
Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L., with analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells .

HY-10585A

Valproic acid sodium 40+ Cited Publications Sodium Valproate sodium	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	Organoid HDAC Autophagy Mitophagy HIV Notch Apoptosis Endogenous Metabolite
Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC₅₀ in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC₅₀, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .

HY-10585

Valproic acid 40+ Cited Publications Dipropylacetic Acid	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	Organoid HDAC Autophagy Mitophagy HIV Notch Apoptosis Endogenous Metabolite
Valproic acid (VPA) is an orally active HDAC inhibitor, with IC₅₀ in the range of 0.5 and 2 mM. Valproic acid inhibits HDAC1 (IC₅₀, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .

HY-10585B

Valproic acid (sodium)(2:1) VPA (sodium)(2:1); 2-Propylpentanoic Acid (sodium)(2:1)	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	HDAC Autophagy Mitophagy HIV Notch Apoptosis Endogenous Metabolite
Valproic acid (VPA) sodium (2:1) is an orally active HDAC inhibitor, with IC₅₀ in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC₅₀, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium (2:1) activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium (2:1) is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .

HY-10585AR

Valproic acid sodium (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Organoid HDAC Autophagy Mitophagy HIV Notch Apoptosis Endogenous Metabolite
Valproic acid (sodium) (Standard) is the analytical standard of Valproic acid (sodium). This product is intended for research and analytical applications. Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC₅₀ in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC₅₀, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .

HY-N8144

Niga-ichigoside F1	Cardiovascular Disease Rhynchosia volubilis Lour. Triterpenes Classification of Application Fields Terpenoids Labiatae Source classification Plants Disease Research Fields	Others
Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis .

HY-N10428

Ganoapplanoid F	Terpenoids Source classification Polyporaceae Plants	Others
Ganoapplanoid F, a highly oxygenated lanostane triterpenoid from Ganoderma applanatum, inhibits lipid accumulation in adipocytes. Ganoapplanoid F can be used for the research of obesity .

HY-B0234

Estrone 5 Publications Verification E1; Oestrone	Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Phenols Endogenous metabolite Disease Research Fields Steroids Cancer	Estrogen Receptor/ERR Endogenous Metabolite
Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells .

HY-N10340

Clausine E Clauszoline I	Structural Classification Alkaloids Classification of Application Fields Source classification Rutaceae Plants Disease Research Fields Clausena harmandiana (Pierre) Guillaumin Cancer	Others
Clausine E, is a alkaloid which can be isolated from Clausena excavata, is a inhibitor of fat mass and obesity-associated protein (FTO) demethylase. Clausine E shows inhibitory activities against proliferation of synoviocytes and cancer cells.

HY-N0023

Cistanoside A	Classification of Application Fields Simple Phenylpropanols Source classification Cistanche deserticola Ma Phenols Polyphenols Orobanchaceae Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology	NO Synthase
Cistanoside A is a phenylethanoid isolated from Cistanche deserticola, reduces NO accumulation, but shows no effect on iNOS mRNA, iNOS protein levels or iNOS activity. Anti-inflammatory effect .

HY-N0723

Neomangiferin	Structural Classification Liliaceae Xanthones Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Anemarrhena asphodeloides Bunge Plants Disease Research Fields	Others
Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats .

HY-N6985

Baccatin III	Structural Classification Classification of Application Fields Terpenoids Taxaceae Source classification Diterpenoids Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	Others
Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs .

Cat. No.	Product Name	Chemical Structure

HY-Y0781S1

Pyruvic acid-13C
Pyruvic acid- ¹³C is the ¹³C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].

HY-B1788S

Taurocholic acid-d4 sodium
Taurocholic acid-d₄ (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

HY-Y0781S

Pyruvic acid-13C sodium
Pyruvic acid- ¹³C (sodium) is the ¹³C-labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-B1788S1

Taurocholic acid-d4
Taurocholic acid-d₄ is deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

HY-B2219S3

Stearic acid-d3
Stearic acid-d₃ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-Y0781S3

Pyruvic acid-13C-2 sodium
Pyruvic acid- ¹³C-2 (sodium) is the ¹³C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].

HY-Y0781S5

Pyruvic acid-13C,d4
Pyruvic acid- ¹³C,d₄ is the deuterium and ¹³C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].

HY-W753983

Pyruvic acid-13C3
Pyruvic acid-13C is isotype-labeled compound of Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats .

HY-B0896S1

Triacetin-d5
Triacetin-d₅ is the deuterium labeled Triacetin. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.

HY-B2219S8

Stearic acid-d1
Stearic acid-d is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S1

Stearic acid-d2
Stearic acid-d₂ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S4

Stearic Acid-d35
Stearic Acid-d₃₅ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S6

Stearic acid-d5
Stearic acid-d₅5 is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S9

Stearic acid-d7
Stearic acid-d₇ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S2

Stearic acid-13C18
Stearic acid- ¹³C₁₈is the ¹³C-labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B0896S2

Triacetin-d9
Glyceryl Triacetate-d₉ is the deuterium labeled Triacetin[1]. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.

HY-N0324S

Cholic acid-d4
Cholic acid-d₄ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N0324S1

Cholic acid-d5
Cholic acid-d₅ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-B2219S

Stearic acid-1-13C
Stearic acid-1- ¹³C is the ¹³C labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N0324S2

Cholic acid-13C
Cholic acid- ¹³C is the ¹³C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-B2219S7

Stearic acid-d4
Stearic acid-d₄ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils[1].

HY-N2041S5

Myristic acid-d1
Myristic acid-d is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S2

Myristic acid-13C
Myristic acid- ¹³C the ¹³C is labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-B2219S5

Stearic acid-9,10-d2
Stearic acid-9,10-d₂ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N2041S4

Myristic acid-13C3
Myristic acid- ¹³C₃ is the ¹³C labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S3

Myristic acid-d3
Myristic acid-d₃3 is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S

Myristic acid-d27 1 Publications Verification
Myristic acid-d₂₇ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S1

Myristic acid-d2
Myristic acid-d₂ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S6

Myristic acid-d5
Myristic acid-d₅ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S7

Myristic acid-d7
Myristic acid-d₇ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N3686S

D-Arabitol-13C
D-Arabitol- ¹³C is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-145612S

Sudan red 7B-d5
Sudan Red 7B-d5 is a deuterated labeled Sudan red 7B . Sudan red 7B is a red non-fluorescent stain that can be used to stain fat bodies .

HY-D0932S

Sudan IV-d6
Sudan IV-d6 is the deuterium labeled Sudan IV(HY-D0932).Sudan IV is a lysochrome (fat-soluble dye) diazo dye used for the staining of lipids, triglycerides and lipoproteins on frozen paraffin sections .

HY-N2334AS

Glycochenodeoxycholic acid-d7 sodium

Glycochenodeoxycholic acid-d₇ (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

HY-N2334S

Glycochenodeoxycholic acid-d4
Glycochenodeoxycholic acid-d₄ is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2].

HY-N3686S1

D-Arabitol-13C-1
D-Arabitol- ¹³C-1 is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-N3686S2

D-Arabitol-13C-2
D-Arabitol- ¹³C-2 is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-B0234S1

Estrone-d2
Estrone-d₂ is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B0234S2

Estrone-d4
Estrone-d₄ is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B0234S4

Estrone-d2-1
Estrone-d₂-1 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B0234S

Estrone-13C3
Estrone- ¹³C₃ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B0234S3

Estrone-13C2
Estrone- ¹³C₂ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-13626S

Spisulosine-d3
Spisulosine-d₃ is deuterium labeled Spisulosine. Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKC

HY-117275S1

Meclofenamic acid-13C6
Meclofenamic acid- ¹³C₆ is the ¹³C₆ labeled Meclofenamic acid. Meclofenamic Acid (Meclofenamate), a non-steroidal, anti-inflammatory agent, is a highly selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic Acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker.

HY-117275S

Meclofenamic acid-d4
Meclofenamic acid-d₄ is the deuterium labeled Meclofenamic acid. Meclofenamic Acid (Meclofenamate), a non-steroidal, anti-inflammatory agent, is a highly selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic Acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker[1][2][3].

HY-W012974S

3-Amino-2-methylpropanoic acid-d3
3-Amino-2-methylpropanoic acid-d₃ is the deuterium labeled 3-Amino-2-methylpropanoic acid[1]. 3-Amino-2-methylpropanoic acid could induce browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors[2].

HY-100935S

Cimaterol-d7
Cimaterol-d₇ is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.

HY-B1885S

Fenitrothion-d6
Fenitrothion-d₆ is the deuterium labeled Fenitrothion[1]. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols[2][3].

HY-135119

Salmeterol-d3
Salmeterol-d₃ is a deuterium labeled Salmeterol. Salmeterol is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1].

HY-14302S1

Salmeterol-d5
Salmeterol-d5 is a deuterated labeled Salmeterol . Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC₅₀s of 9.6, 6.1, and 5.9, respectively .

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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks