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Synthetic

" in MedChemExpress (MCE) Product Catalog:

866

Inhibitors & Agonists

13

Screening Libraries

46

Fluorescent Dye

65

Biochemical Assay Reagents

188

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2

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69

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104

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20

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34

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1662
    Hexestrol
    1 Publications Verification

    Estrogen Receptor/ERR Endocrinology
    Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle .
    Hexestrol
  • HY-P10462

    Synthetic anti-inflammatory peptide 15

    HDAC NF-κB Inflammation/Immunology
    SAP15 (Synthetic anti-inflammatory peptide 15) is a synthetic anti-inflammatory peptide consisting of 15 amino acids designed from human beta-defensin 3. SAP15 has the ability to penetrate cells and is able to induce downregulation of intracellular inflammation. SAP15 inhibits inflammation by inhibiting the phosphorylation of HDAC5 and thereby reducing the phosphorylation of NF-κB p65. In LPS-induced macrophages, SAP15 inhibits HDAC5 and NF-κB p65 phosphorylation. In addition, SAP15 treatment increased the expression of aggrecan and type II collagen and decreased the expression of osteocalcin in LPS-induced chondrocytes. SAP15 can be used in the study of inflammation regulation and anti-inflammatory therapy of biomaterials .
    SAP15
  • HY-166863

    Biochemical Assay Reagents Others
    L-erythro-Sphingosine(synthetic) is a biochemical assay reagent.
    L-erythro-Sphingosine(synthetic)
  • HY-P1459

    Bacterial Infection
    Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.
    Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)
  • HY-114582

    Others Others
    Lexitropsin is a netropsin derivative which is determined the binding and specificity properties in interaction with DNA and synthetic polynucleotides .
    Lexitropsin
  • HY-P10082

    Caspase Others
    Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. Ac-VETD-AMC also has potential to assess functional activity of recombinant phytaspase .
    Ac-VETD-AMC
  • HY-161752

    Bacterial Infection
    Antibacterial agent 224 is a potent and selective synthetic hydrazone inhibitor against the Salmonella PhoP/PhoQ system .
    Antibacterial agent 224
  • HY-106365

    Others Endocrinology
    Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models .
    Rofleponide
  • HY-122245

    Others Cancer
    Sortin2 is a synthetic compound. Sortin2 can affect protein targeting to the vacuole in Saccharomyces cerevisiae .
    Sortin2
  • HY-B1662R

    Estrogen Receptor/ERR Endocrinology
    Hexestrol (Standard) is the analytical standard of Hexestrol. This product is intended for research and analytical applications. Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle .
    Hexestrol (Standard)
  • HY-117444

    LPL Receptor Cancer
    ONO-9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC50 value of 2.7 nM .
    ONO-9780307
  • HY-D1373

    HBC 530

    DNA Stain Cancer
    HBC is a green fluorescent protein (GFP) fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is used to detect RNA localization .
    HBC
  • HY-W351340

    Fluorescent Dye Others
    4-(Benzyloxy)-2-nitrophenol is a synthetic building block that can be used in the synthesis of fluorescent ion indicators .
    4-(Benzyloxy)-2-nitrophenol
  • HY-P1701

    Opioid Receptor Cardiovascular Disease Neurological Disease
    Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors .
    Morphiceptin
  • HY-N8495

    Others Metabolic Disease
    4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. 4'-Hydroxyflavanone is a synthetic analogue of flavanone, has potential for hepatic steatosis and dyslipidemia research .
    4'-Hydroxyflavanone
  • HY-W250152

    Biochemical Assay Reagents Inflammation/Immunology
    Polycytidylic acid potassium is an immunostimulant and synthetic double-stranded RNA. Polycytidylic acid potassium can be used experimentally to model viral infections in vivo. Polycytidylic acid potassium is a common tool in immune system research .
    Polycytidylic acid potassium
  • HY-112205

    Legumain Cancer
    RR-11a is a synthetic enzyme inhibitor of Legumain (IC50=31-55 nM). RR-11a can be used for the research of cancer and acute myocardial infarction (AMI) .
    RR-11a
  • HY-167545

    POPE

    Liposome Biochemical Assay Reagents Others
    1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid that can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine can be used in drug delivery research .
    1-Palmitoyl-2-oleoylphosphatidylethanolamine
  • HY-109127A
    Berotralstat dihydrochloride
    1 Publications Verification

    BCX7353 dihydrochloride

    Kallikrein Others
    Berotralstat dihydrochloride is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat dihydrochloride works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE .
    Berotralstat dihydrochloride
  • HY-109127
    Berotralstat
    1 Publications Verification

    BCX7353

    Kallikrein Others
    Berotralstat (BCX7353) is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE .
    Berotralstat
  • HY-N4115
    Syrosingopine
    4 Publications Verification

    Su 3118

    Monocarboxylate Transporter Cardiovascular Disease Cancer
    Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine .
    Syrosingopine
  • HY-P5309

    Biochemical Assay Reagents Inflammation/Immunology
    (Thr(GalNAc)4,7,15,Ser(GalNAc)9,11)-IgA1 Hinge Region Peptide is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .
    (Thr(GalNAc)4,7,15,Ser(GalNAc)9,11)-IgA1 Hinge Region Peptide
  • HY-109127R

    Ser/Thr Protease Others
    Berotralstat (Standard) is the analytical standard of Berotralstat. This product is intended for research and analytical applications. Berotralstat (BCX7353) is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE .
    Berotralstat (Standard)
  • HY-145860

    Phosphoglycerate Dehydrogenase (PHGDH) Cancer
    PHGDH-IN-2 is a potent and NAD + competitive PHGDH inhibitor with an IC50 of 5.2 µM. PHGDH-IN-2 inhibits the serine synthetic pathway in MDA-MB-468 cells. PHGDH-IN-2 inhibits the growth of PHGDH-dependent cancer cells .
    PHGDH-IN-2
  • HY-151661

    L-azidovaline (CHA)

    ADC Linker Others
    N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    N3-L-Val-OH (CHA)
  • HY-B1278B

    (±)-Vitamin E acetate

    Biochemical Assay Reagents Infection
    (±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases .
    (±)-α-Tocopherol acetate
  • HY-145268

    Others Cancer
    SLEC-11 acts as a potential synthetic lethal lead for the research of gastric cancer. AL-GDa62 shows EC50 of 12.2 μM and 8.2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1 -/- .
    SLEC-11
  • HY-145269

    Others Cancer
    AL-GDa62 acts as a potential synthetic lethal lead for the research of gastric cancer. AL-GDa62 shows EC50 of 3.2 μM and 2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1 -/- .
    AL-GDa62
  • HY-114671

    CG-4203

    Prostaglandin Receptor Cardiovascular Disease
    Taprostene (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2). Taprostene exhibits endothelium and myocardial protecting actions after acute myocardial ischemia and reperfusion in cats. Taprostene enhances cytoprotective actions, while minimizing unwanted hemodynamic effects .
    Taprostene
  • HY-134581A
    Enpatoran hydrochloride
    5 Publications Verification

    M5049 hydrochloride

    Toll-like Receptor (TLR) Inflammation/Immunology
    Enpatoran (M5049) hydrochloride is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran hydrochloride is inactive against TLR3, TLR4 and TLR9. Enpatoran hydrochloride can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran hydrochloride exhibits excellent pharmacokinetic properties in vivo. Enpatoran hydrochloride can be used for both innate and adaptive autoimmunity blocking research .
    Enpatoran hydrochloride
  • HY-131701

    C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine; Lyso-Lactosylceramide (Synthetic)

    Endogenous Metabolite Metabolic Disease
    Lactosyl-C18-sphingosine (C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine) is a bioactive sphingolipid that is a form of lactosylceramide but lacks the fatty acyl group. Lysolactosylceramide (1-50 μM) reduces the viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosyl-C18-sphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosyl-C18-sphingosine is a lysoganglioside GM3.
    Lactosyl-C18-sphingosine
  • HY-119506
    KL044
    1 Publications Verification

    Cryptochrome Metabolic Disease
    KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity .
    KL044
  • HY-P1626

    Opioid Receptor Neurological Disease
    Acetyl tetrapeptide-15 is a synthetic peptide used in the cosmetics for sensitive skin. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway .
    Acetyl tetrapeptide-15
  • HY-B1182

    Chromone-2-carboxylic acid

    Others Cardiovascular Disease
    Chromocarb is a synthetic vasoprotectant.
    Chromocarb
  • HY-17405
    Alarelin Acetate
    1 Publications Verification

    Alarelin

    GnRH Receptor Endocrinology
    Alarelin acetate is a synthetic GnRH agonist.
    Alarelin Acetate
  • HY-100268

    Xenazoic acid; CV58903

    Antibiotic Infection
    Xenalamine is a synthetic antiviral agent.
    Xenalamine
  • HY-P3375

    IBI-362; LY-3305677; OXM-3

    GCGR GLP Receptor Metabolic Disease
    Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide binds human and mouse GCGR (Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC50: 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D) .
    Mazdutide
  • HY-101829

    Sulfaproxylin; Sulfaproxyline

    Bacterial Infection
    Sulfaproxiline is a synthetic antimicrobial agent that is sulfonamide.
    Sulfaproxiline
  • HY-P3375A

    IBI-362 TFA; LY-3305677 TFA; OXM-3 TFA

    GCGR GLP Receptor Metabolic Disease
    Mazdutide (IBI-362; LY-3305677) TFA is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide TFA binds human and mouse GCGR (Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC50: 5.2 nM). Mazdutide TFA is used in studies of obesity and type 2 diabetes (T2D) .
    Mazdutide TFA
  • HY-101575

    Acetylkelfizina; Acetylsulfamethoxypyrazine; FI6073

    Bacterial Antibiotic Infection
    Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.
    Acetylazide
  • HY-B0896

    Glyceryl triacetate; 1,2,3-Triacetoxypropane

    Fungal Endogenous Metabolite Others
    Triacetin is a synthetic compound that is a triester of glycerol and acetic acid.
    Triacetin
  • HY-B0989

    4-Sulfamoylbenzoic acid

    Others Others
    Carzenide is an organic synthesis intermediate, for synthetic drug.
    Carzenide
  • HY-B1203

    9α-Fludrocortisone; 9α-Fluorcortisol

    Mineralocorticoid Receptor Inflammation/Immunology
    Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.
    Fludrocortisone
  • HY-U00089

    Glucocorticoid Receptor Inflammation/Immunology Endocrinology
    Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
    Hydrocortisone cypionate
  • HY-101703
    Ro 31-9790
    1 Publications Verification

    GI4747

    MMP Inflammation/Immunology
    Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor.
    Ro 31-9790
  • HY-B1072

    Parasite Infection
    Phenothrin is a synthetic pyrethroid that kills adult fleas and ticks.
    Phenothrin
  • HY-P0290
    GRGDSP
    4 Publications Verification

    Integrin Cancer
    GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
    GRGDSP
  • HY-U00098

    Glucocorticoid Receptor Inflammation/Immunology Endocrinology
    Prednisolone tebutate is a synthetic glucocorticoid used as an antiinflammatory and immunosuppressant.
    Prednisolone Tebutate
  • HY-100245

    Thrombin Cardiovascular Disease
    OM-189 is a selective synthetic thrombin inhibitor.
    OM-189
  • HY-U00043

    Glucocorticoid Receptor Inflammation/Immunology Endocrinology
    Triamcinolone benetonide is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
    Triamcinolone Benetonide

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