Egfr - epidermal growth factor receptor Gene

Mus musculus

Also known as Wa5; wa2; Erbb; Errp; wa-2; Errb1; 9030024J15Rik

Gene ID: 13649 | Gene type: protein coding

About Egfr

Chromosome 11: 16,702,203-16,868,158 forward strand.GRCm39:CM001004.3

This gene has 5 transcripts (splice variants), 283 orthologues, 53 paralogues and is associated with 180 phenotypes. Broad expression in liver adult (RPKM 26.7), liver E18 (RPKM 8.7) and 15 other tissues.

Summary

Enables epidermal growth factor binding activity and epidermal growth factor-activated receptor activity. Involved in cellular response to amino acid stimulus and positive regulation of fibroblast proliferation. Acts upstream of or within several processes, including animal organ development; epidermal growth factor receptor signaling pathway; and protein autophosphorylation. Located in several cellular components, including basolateral plasma membrane; endocytic vesicle; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; integumental system; limb; and respiratory system. Used to study Coronavirus infectious disease and aortic valve disease. Human ortholog(s) of this gene implicated in several diseases, including colorectal cancer; lung non-small cell carcinoma (multiple); pancreatic cancer; prostate cancer; and pulmonary tuberculosis. Orthologous to human EGFR (epidermal growth factor receptor). [provided by Alliance of Genome Resources, Apr 2022]

Egfr Products(2)

mRNA	Protein	Name
NM_207655.2	NP_997538.1	epidermal growth factor receptor isoform 1 precursor
NM_007912.4	NP_031938.1	epidermal growth factor receptor isoform 2 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables epidermal growth factor binding	IDA IDA: Inferred from direct assay	7678348	MGI
enables epidermal growth factor receptor activity	IDA IDA: Inferred from direct assay	6248866	MGI
enables epidermal growth factor receptor activity	IGI IGI: Inferred from genetic interaction	16357442	MGI
enables epidermal growth factor receptor activity	IMP IMP: Inferred from mutant phenotype	18701712	MGI
enables kinase activity	IDA IDA: Inferred from direct assay	12808090	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	11274221	MGI
enables protein tyrosine kinase activity	IDA IDA: Inferred from direct assay	15383614	MGI
enables protein tyrosine kinase activity	IMP IMP: Inferred from mutant phenotype	11823423	MGI
enables transmembrane receptor protein tyrosine kinase activity	IDA IDA: Inferred from direct assay	7752576	MGI
enables transmembrane receptor protein tyrosine kinase activity	IGI IGI: Inferred from genetic interaction	28783046	MGI
enables transmembrane receptor protein tyrosine kinase activity	IMP IMP: Inferred from mutant phenotype	12399441	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in ERBB2-EGFR signaling pathway	IDA IDA: Inferred from direct assay	8702723	MGI
involved in ERBB2-EGFR signaling pathway	IMP IMP: Inferred from mutant phenotype	18701712	MGI
acts upstream of or within cell morphogenesis	IGI IGI: Inferred from genetic interaction	17686994	MGI
acts upstream of cell population proliferation	IGI IGI: Inferred from genetic interaction	18656477	MGI
involved in cellular response to amino acid stimulus	IDA IDA: Inferred from direct assay	22711986	MGI
acts upstream of or within cellular response to growth factor stimulus	IDA IDA: Inferred from direct assay	8702723	MGI
acts upstream of or within cerebral cortex cell migration	IMP IMP: Inferred from mutant phenotype	7618084	MGI
acts upstream of or within digestive tract morphogenesis	IMP IMP: Inferred from mutant phenotype	7618084	MGI
acts upstream of or within embryonic placenta development	IMP IMP: Inferred from mutant phenotype	7618084	MGI
acts upstream of or within epidermal growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	14712229	MGI
involved in epidermal growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	6248866	MGI
acts upstream of or within epidermal growth factor receptor signaling pathway	IGI IGI: Inferred from genetic interaction	7641815	MGI
involved in epidermal growth factor receptor signaling pathway	IGI IGI: Inferred from genetic interaction	28783046	MGI
acts upstream of or within epidermal growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	17686994	MGI
involved in epidermal growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	12399441	MGI
acts upstream of or within epidermis development	IMP IMP: Inferred from mutant phenotype	7618084	MGI
acts upstream of epithelial cell proliferation	IMP IMP: Inferred from mutant phenotype	7618084	MGI
acts upstream of or within eyelid development in camera-type eye	IGI IGI: Inferred from genetic interaction	9030684	MGI
acts upstream of or within hair follicle development	IGI IGI: Inferred from genetic interaction	9030684	MGI
acts upstream of or within hair follicle development	IMP IMP: Inferred from mutant phenotype	7618084	MGI
acts upstream of or within morphogenesis of an epithelial fold	IMP IMP: Inferred from mutant phenotype	7618084	MGI
involved in negative regulation of epidermal growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	23457600	MGI
involved in negative regulation of epidermal growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	11823423	MGI
acts upstream of or within positive regulation of cell population proliferation	IDA IDA: Inferred from direct assay	14712229	MGI
acts upstream of or within positive regulation of cell population proliferation	IGI IGI: Inferred from genetic interaction	7641815	MGI
acts upstream of or within positive regulation of epithelial cell proliferation	IMP IMP: Inferred from mutant phenotype	7618084	MGI
involved in positive regulation of fibroblast proliferation	IMP IMP: Inferred from mutant phenotype	20208556	MGI
acts upstream of or within protein autophosphorylation	IDA IDA: Inferred from direct assay	15314156	MGI
acts upstream of or within regulation of cell population proliferation	IGI IGI: Inferred from genetic interaction	11818567	MGI
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation	IMP IMP: Inferred from mutant phenotype	11940581	MGI
acts upstream of or within salivary gland morphogenesis	IMP IMP: Inferred from mutant phenotype	10521784	MGI
acts upstream of or within signal transduction	IDA IDA: Inferred from direct assay	11940581	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	7723235	MGI
located in cell surface	IDA IDA: Inferred from direct assay	23918928	MGI
located in endocytic vesicle	IDA IDA: Inferred from direct assay	10534613	MGI
located in intracellular anatomical structure	IDA IDA: Inferred from direct assay	10534613	MGI
located in nucleus	IDA IDA: Inferred from direct assay	20208556	MGI
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	20208556	MGI
is active in plasma membrane	IDA IDA: Inferred from direct assay	6248866	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	7641815	MGI
is active in plasma membrane	IGI IGI: Inferred from genetic interaction	28783046	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Egfr Protein Structure

Recep_L_domain

Furin-like

Recep_L_domain

GF_recep_IV

TM_ErbB1

PTKc_EGFR

0
200
400
600
800
1000
1210 a.a.

Protein Preferred Names

Protein Names

epidermal growth factor receptor

avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

waved 2

Recombinant Egfr Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72988	EGFR Protein, Mouse (HEK293, Fc)	Q01279 (L25-S647)	≥95%
HY-P72989	EGFR Protein, Mouse (HEK293, His)	Q01279 (L25-S647)	≥95%

Related Agents

Approval

Bioactive Molecules (46)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15772	Osimertinib	Inhibitor	99.96%	Yes
HY-50895	Gefitinib	Inhibitor	99.95%	Yes
HY-50896	Erlotinib	Inhibitor	99.99%	Yes
HY-138298A	Trastuzumab deruxtecan	Inhibitor	99.68%	Unkown
HY-10261	Afatinib	Inhibitor	99.92%	Yes
HY-50898	Lapatinib	Inhibitor	99.83%	Yes
HY-138298	Trastuzumab deruxtecan (solution)	Inhibitor	99.64%	Unkown
HY-P9921	Trastuzumab emtansine	Inhibitor	99.74%	Unkown
HY-16069	Tucatinib	Inhibitor	99.82%	Yes
HY-32721	Neratinib	Inhibitor	99.94%	Yes
HY-P9985	Disitamab vedotin	Inhibitor	≥99.0%	Unkown
HY-13272	Dacomitinib	Inhibitor	99.74%	Yes
HY-15772A	Osimertinib mesylate	Inhibitor	99.97%	Yes
HY-109061	Lazertinib	Inhibitor	99.87%	Unkown
HY-12008	Erlotinib Hydrochloride	Inhibitor	99.94%	Yes
HY-112823	Almonertinib	Inhibitor	99.83%	Unkown
HY-135815	Mobocertinib	Inhibitor	99.60%	Yes
HY-104065	Pyrotinib	Inhibitor	99.89%	Unkown
HY-10261A	Afatinib dimaleate	Inhibitor	99.74%	Yes
HY-112870A	Firmonertinib mesylate	Inhibitor	99.97%	Unkown
HY-15164A	Icotinib	Inhibitor	99.99%	Yes
HY-50895A	Gefitinib hydrochloride	Inhibitor	99.85%	Yes
HY-N0281	Daphnetin	Inhibitor	99.86%	Unkown
HY-P9921A	Trastuzumab emtansine (solution)		99.01%	Unkown
HY-19730	Olmutinib	Inhibitor	99.88%	Unkown
HY-79077	Osimertinib dimesylate	Inhibitor	99.96%	Yes
HY-50898A	Lapatinib ditosylate	Inhibitor	99.98%	Yes
HY-104065B	Pyrotinib dimaleate	Inhibitor	98.56%	Unkown
HY-112823A	Almonertinib mesylate	Inhibitor	99.67%	Unkown
HY-50898B	Lapatinib ditosylate monohydrate	Inhibitor	99.93%	Yes
HY-15164	Icotinib Hydrochloride	Inhibitor	99.81%	Yes
HY-112870	Firmonertinib	Inhibitor	99.89%	Unkown
HY-32721B	Neratinib maleate	Inhibitor	99.83%	Yes
HY-135815A	Mobocertinib succinate	Inhibitor	99.83%	Yes
HY-112823B	Almonertinib hydrochloride	Inhibitor	99.77%	Unkown
HY-16069A	Tucatinib hemiethanolate	Inhibitor	99.97%	Yes
HY-118263	Dacomitinib hydrate	Inhibitor	99.03%	Unkown
HY-101820	Simotinib	Inhibitor	99.39%	Unkown
HY-50895R	Gefitinib (Standard)	Inhibitor	/	Unkown
HY-15772R	Osimertinib (Standard)	Inhibitor	/	Unkown
HY-135815B	Mobocertinib mesylate	Inhibitor	/	Unkown
HY-50898C	Lapatinib tosylate	Inhibitor	/	Unkown
HY-50895B	Gefitinib dihydrochloride	Inhibitor	/	Unkown
HY-10261D	Afatinib oxalate	Inhibitor	/	Unkown
HY-101820A	Simotinib hydrochloride	Inhibitor	/	Unkown
HY-12008A	Erlotinib mesylate	Inhibitor	/	Unkown

Inhibitory Antibodies (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9907	Trastuzumab	Inhibitor	99.80%	Unkown
HY-P9905	Cetuximab	Inhibitor	99.70%	Unkown
HY-P9977	Amivantamab	Inhibitor	99.90%	Unkown
HY-P9912	Pertuzumab	Inhibitor	99.80%	Unkown
HY-P99041	Panitumumab	Inhibitor	98.80%	Unkown
HY-P99380	Zanidatamab	Inhibitor	96.38%	Unkown
HY-P99507	Zenocutuzumab	Inhibitor	99.20%	Unkown
HY-P9968	Nimotuzumab	Inhibitor	96.80%	Unkown
HY-P99030	Margetuximab	Inhibitor	≥99.0%	Unkown
HY-P9964	Necitumumab	Inhibitor	99.51%	Unkown

Clinical Phase

Bioactive Molecules (67)

Cat. No.	Product Name	Effect	Purity	Phase
HY-14596	Genistein	Inhibitor	99.82%	Phase 4
HY-50895G	Gefitinib (GMP)	Inhibitor	/	Phase 4
HY-132842	Sunvozertinib	Inhibitor	99.71%	Phase 3
HY-18750	Zorifertinib	Inhibitor	99.37%	Phase 3
HY-19816	Avitinib	Inhibitor	99.95%	Phase 3
HY-15729	Rociletinib	Inhibitor	99.79%	Phase 3
HY-13314	Tesevatinib	Inhibitor	99.41%	Phase 3
HY-10530	Varlitinib	Inhibitor	98.03%	Phase 3
HY-12872	Nazartinib	Inhibitor	99.03%	Phase 3
HY-138751	limertinib	Inhibitor	99.12%	Phase 3
HY-19816A	Avitinib maleate	Inhibitor	99.86%	Phase 3
HY-132259	Depatuxizumab mafodotin		99.73%	Phase 3
HY-19803	Naquotinib mesylate	Inhibitor	98.05%	Phase 3
HY-19729	Naquotinib	Inhibitor	98.71%	Phase 3
HY-15729A	Rociletinib hydrobromide	Inhibitor	98.04%	Phase 3
HY-18750A	Zorifertinib hydrochloride	Inhibitor	/	Phase 3
HY-139920A	Oritinib mesylate	Inhibitor	/	Phase 3
HY-118998	TX2-121-1	Inhibitor	/	Phase 3
HY-10530A	Varlitinib tosylate	Inhibitor	/	Phase 3
HY-137433A	Befotertinib mesylate	Inhibitor	/	Phase 3
HY-106204	Nelipepimut-S		/	Phase 3
HY-13050	Sapitinib	Inhibitor	99.93%	Phase 2
HY-144680	BLU-945	Inhibitor	99.80%	Phase 2
HY-32718	Pelitinib	Inhibitor	99.13%	Phase 2
HY-10367	Canertinib	Inhibitor	99.74%	Phase 2
HY-14674	CP-724714	Inhibitor	98.37%	Phase 2
HY-10333	BMS-690514	Inhibitor	99.07%	Phase 2
HY-10045	AEE788	Inhibitor	99.13%	Phase 2
HY-112299	Zipalertinib	Inhibitor	99.81%	Phase 2
HY-153268	Silevertinib	Inhibitor	99.03%	Phase 2
HY-12972	Mavelertinib	Inhibitor	99.34%	Phase 2
HY-13427	Allitinib tosylate	Inhibitor	99.83%	Phase 2
HY-136789	Tuxobertinib	Inhibitor	99.90%	Phase 2
HY-19985	PF-06459988	Inhibitor	98.87%	Phase 2
HY-157229	STX-721	Inhibitor	98.25%	Phase 2
HY-10367A	Canertinib dihydrochloride	Inhibitor	99.68%	Phase 2
HY-107367A	Epertinib hydrochloride	Inhibitor	98.15%	Phase 2
HY-17632	Tarloxotinib bromide	Inhibitor	99.26%	Phase 2
HY-156640	Rocbrutinib	Inhibitor	99.76%	Phase 2
HY-19909	NRC-2694	Antagonist	99.45%	Phase 2
HY-107367	Epertinib	Inhibitor	≥98.0%	Phase 2
HY-12872A	Nazartinib mesylate	Inhibitor	/	Phase 2
HY-19981B	Derazantinib dihydrochloride	Inhibitor	/	Phase 2
HY-10223	CUDC-101	Inhibitor	99.05%	Phase 1
HY-18957	Lifirafenib	Inhibitor	98.73%	Phase 1
HY-13501	Mubritinib	Inhibitor	99.91%	Phase 1
HY-14346	PD153035	Inhibitor	98.83%	Phase 1
HY-15196	TAK-285	Inhibitor	99.70%	Phase 1
HY-10322	Falnidamol	Inhibitor	99.41%	Phase 1
HY-B0794B	AZ7550 Mesylate	Inhibitor	99.24%	Phase 1
HY-103443	HKI-357	Inhibitor	99.24%	Phase 1
HY-116437	Selatinib	Inhibitor	99.83%	Phase 1
HY-12010	BMS-599626 Hydrochloride	Inhibitor	99.68%	Phase 1
HY-111553	TAS0728	Inhibitor	99.71%	Phase 1
HY-143319	SPH5030	Inhibitor	99.40%	Phase 1
HY-10346A	AV-412 free base	Inhibitor	98.33%	Phase 1
HY-104066	Theliatinib	Inhibitor	99.77%	Phase 1
HY-10346	AV-412	Inhibitor	99.17%	Phase 1
HY-128778	Gozanertinib	Inhibitor	98.37%	Phase 1
HY-139300A	Epitinib succinate	Inhibitor	99.01%	Phase 1
HY-B0794	AZ7550	Inhibitor	/	Phase 1
HY-B0794A	AZ7550 hydrochloride	Inhibitor	98.66%	Phase 1
HY-15732	BGB-102	Inhibitor	99.52%	Phase 1
HY-104066A	Theliatinib tartrate		/	Phase 1
HY-139300	Epitinib	Inhibitor	/	Phase 1
HY-10251	BMS-599626	Inhibitor	/	Phase 1
HY-18957B	Lifirafenib maleate	Inhibitor	/	Phase 1

Inhibitory Antibodies (36)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P9907A	Trastuzumab (anti-HER2)	Inhibitor	99.72%	Phase 4
HY-P99854	Disitamab	Inhibitor	98.70%	Phase 4
HY-P99041A	Panitumumab (anti-EGFR)	Inhibitor	98.00%	Phase 4
HY-P99969	Inetetamab	Inhibitor	96.54%	Phase 4
HY-P99275	Patritumab	Inhibitor	98.95%	Phase 3
HY-P99406	Petosemtamab	Degrader	96.95%	Phase 3
HY-P99676	Izalontamab	Inhibitor	99.89%	Phase 3
HY-P99849	Depatuxizumab	Inhibitor	99.58%	Phase 3
HY-P99155	Zalutumumab		98.34%	Phase 3
HY-P99455	Bafisontamab	Inhibitor	96.00%	Phase 3
HY-P990049	Becotatug	Inhibitor	98.44%	Phase 3
HY-P99437	Anbenitamab	Inhibitor	99.22%	Phase 3
HY-P99630	Gancotamab	Inhibitor	/	Phase 3
HY-P99831	Coprelotamab		/	Phase 3
HY-P990697	Anvatabart	Inhibitor	/	Phase 3
HY-P99268	Seribantumab	Inhibitor	≥95.0%	Phase 2
HY-P9969	Matuzumab		98.12%	Phase 2
HY-P99936	Elgemtumab	Inhibitor	99.00%	Phase 2
HY-P99778	Ontuxizumab		99.85%	Phase 2
HY-P99866	Duligotuzumab		97.93%	Phase 2
HY-P990314	AFM24	Inhibitor	96.26%	Phase 2
HY-P99216	Ponezumab	Inhibitor	99.39%	Phase 2
HY-P99715	Losatuxizumab	Inhibitor	99.44%	Phase 2
HY-P99296	Intetumumab	Inhibitor	99.24%	Phase 2
HY-P99306	Modotuximab	Inhibitor	99.08%	Phase 2
HY-P99618	Fidasimtamab	Inhibitor	95.00%	Phase 2
HY-P99605	Cinrebafusp alfa	Inhibitor	98.53%	Phase 2
HY-P99295	Imgatuzumab	Inhibitor	99.41%	Phase 2
HY-P99628	Futuximab	Inhibitor	98.09%	Phase 2
HY-P99672	Istiratumab	Inhibitor	98.45%	Phase 2
HY-P99500	Cetuximab sarotalocan	Inhibitor	/	Phase 2
HY-P99921	Enapotamab vedotin	Inhibitor	/	Phase 2
HY-P99386	Vesencumab	Inhibitor	≥99.0%	Phase 1
HY-P99896	Runimotamab		99.00%	Phase 1
HY-P99304	Lumretuzumab	Inhibitor	≥99.0%	Phase 1
HY-P99461	Barecetamab	Inhibitor	97.96%	Phase 1

Pre-clinical Phase

Bioactive Molecules (643)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12000	AG490	Inhibitor	99.86%	Unkown
HY-13524	AG-1478	Inhibitor	99.57%	Unkown
HY-101084	NSC 228155	Activator	≥98.0%	Unkown
HY-N0280	Corosolic acid		99.67%	Unkown
HY-N2409	Delphinidin chloride	Inhibitor	≥98.0%	Unkown
HY-13595	Chrysophanol	Inhibitor	99.77%	Unkown
HY-16558	Butein	Inhibitor	99.95%	Unkown
HY-100848	TX1-85-1	Inhibitor	98.04%	Unkown
HY-P10408	Candidalysin	Activator	99.38%	Unkown
HY-12461	WS6	Activator	99.94%	Unkown
HY-B0793	AZ-5104	Inhibitor	99.69%	Unkown
HY-123921	Gefitinib-based PROTAC 3	Inhibitor	99.98%	Unkown
HY-15730	Poziotinib	Inhibitor	99.96%	Unkown
HY-100958	4-DAMP	Inhibitor	99.99%	Unkown
HY-N0447	8-Gingerol	Inhibitor	99.82%	Unkown
HY-100213	EAI045	Inhibitor	99.08%	Unkown
HY-15644	Tyrphostin 23	Inhibitor	98.19%	Unkown
HY-13896	PD168393	Inhibitor	98.58%	Unkown
HY-18609	PD158780	Inhibitor	99.56%	Unkown
HY-112411	PD 174265	Inhibitor	98.72%	Unkown
HY-12026	WZ4002	Inhibitor	98.99%	Unkown
HY-108052	Delphinidin 3-glucoside chloride	Inhibitor	99.89%	Unkown
HY-141676	HyT36	Degrader	/	Unkown
HY-14596R	Genistein (Standard)	Inhibitor	99.31%	Unkown
HY-147183B	JBJ-09-063 hydrochloride	Inhibitor	99.37%	Unkown
HY-109189	Rezivertinib	Inhibitor	99.43%	Unkown
HY-162713	MTX-531	Inhibitor	99.87%	Unkown
HY-129550	BI-4020	Inhibitor	99.28%	Unkown
HY-15844	AG-825	Inhibitor	98.02%	Unkown
HY-120852	JG26	Inhibitor	98.01%	Unkown
HY-W016412	Coenzyme Q0	Inhibitor	99.88%	Unkown
HY-14596S	Genistein-d4	Inhibitor	98.81%	Unkown
HY-164992	Trastuzumab MMAE	Inhibitor	96.02%	Unkown
HY-125168	EGA	Modulator	≥99.0%	Unkown
HY-12001	WZ-3146	Inhibitor	99.63%	Unkown
HY-100434	PD-161570	Inhibitor	99.82%	Unkown
HY-P1845A	PACAP-38 (31-38), human, mouse, rat TFA	Inducer	98.33%	Unkown
HY-111138	CZC-8004	Inhibitor	99.81%	Unkown
HY-P1845	PACAP-38 (31-38), human, mouse, rat	Inducer	99.98%	Unkown
HY-N0211	Cyasterone	Inhibitor	99.58%	Unkown
HY-137433	Befotertinib	Inhibitor	99.86%	Unkown
HY-N2450	Sulforaphene	Inhibitor	99.80%	Unkown
HY-10325	CL-387785	Inhibitor	98.05%	Unkown
HY-144880	SC209	Inhibitor	99.52%	Unkown
HY-137191	CH7233163	Inhibitor	99.61%	Unkown
HY-147941A	MS9427 TFA	Degrader	99.01%	Unkown
HY-N2510	Myristicin	Inhibitor	99.89%	Unkown
HY-78869	Mutated EGFR-IN-1	Inhibitor	99.89%	Unkown
HY-134877	BAY 2476568	Inhibitor	99.88%	Unkown
HY-141640	MS154	Inhibitor	99.42%	Unkown
HY-13895	WHI-P154	Inhibitor	99.39%	Unkown
HY-124813	PDZ1i	Inhibitor	99.29%	Unkown
HY-101219	VEGFR-IN-1	Inhibitor	98.42%	Unkown
HY-41404	Piperonylic acid		99.91%	Unkown
HY-123578	NSC689857	Inhibitor	99.65%	Unkown
HY-20878	Tyrphostin AG 879	Inhibitor	99.85%	Unkown
HY-155537	Pruvonertinib	Inhibitor	99.50%	Unkown
HY-19815	Olafertinib	Inhibitor	99.51%	Unkown
HY-107364	MTX-211	Inhibitor	99.81%	Unkown
HY-130616	EGFR-IN-11	Inhibitor	99.30%	Unkown
HY-103442	CGP52411	Inhibitor	99.82%	Unkown
HY-150611	EGFR-IN-70	Inhibitor	99.16%	Unkown
HY-10261B	(E/Z)-Afatinib	Inhibitor	99.98%	Unkown
HY-103440	EGFR/ErbB-2/ErbB-4 inhibitor-3	Inhibitor	98.19%	Unkown
HY-15375	Allitinib	Inhibitor	99.36%	Unkown
HY-18603	FIIN-3	Inhibitor	99.66%	Unkown
HY-142283AS	Dosimertinib mesylate	Inhibitor	99.44%	Unkown
HY-128576	DS21360717		99.80%	Unkown
HY-147219A	SIAIS164018 hydrochloride	Inhibitor	99.84%	Unkown
HY-101450	PF-6274484	Inhibitor	98.76%	Unkown
HY-120590	Ruserontinib	Inhibitor	99.82%	Unkown
HY-162299	EGFR kinase inhibitor 3	Inhibitor	99.03%	Unkown
HY-B1394	Khellin	Inhibitor	99.89%	Unkown
HY-18963	Lavendustin A	Inhibitor	98.02%	Unkown
HY-155736	MAPK-IN-2	Inhibitor	98.54%	Unkown
HY-N1166	Tephrosin		98.02%	Unkown
HY-N2184	Furanodienone		99.90%	Unkown
HY-43533	Tarlox-TKI	Inhibitor	98.84%	Unkown
HY-107459	(E/Z)-AG490	Inhibitor	99.71%	Unkown
HY-101041	(E)-AG 556	Inhibitor	99.92%	Unkown
HY-12029	WZ8040	Inhibitor	99.22%	Unkown
HY-139920	Oritinib	Inhibitor	99.59%	Unkown
HY-150023	BI-1622	Inhibitor	98.97%	Unkown
HY-138627A	AST5902 trimesylate	Inhibitor	98.75%	Unkown
HY-12013	PD153035 Hydrochloride	Inhibitor	99.48%	Unkown
HY-153110A	Larotinib mesylate hydrate	Inhibitor	98.66%	Unkown
HY-N4201	β-Hydroxyisovalerylshikonin	Inhibitor	99.83%	Unkown
HY-112293	GW2974		99.54%	Unkown
HY-P5314	OK2	Inhibitor	95.95%	Unkown
HY-15801	HG-14-10-04	Inhibitor	99.09%	Unkown
HY-103566	LY456236	Inhibitor	99.81%	Unkown
HY-157581	MS39	Degrader	99.89%	Unkown
HY-115481	EphB1-IN-1	Inhibitor	99.87%	Unkown
HY-124674A	CCT365623 hydrochloride	Inhibitor	98.07%	Unkown
HY-123952	RTC-5	Inhibitor	99.89%	Unkown
HY-17499	EGFR-IN-12	Inhibitor	99.40%	Unkown
HY-131865	SJF-1521	Degrader	99.65%	Unkown
HY-147942	MS9449		98.95%	Unkown
HY-150024	BI-4142	Inhibitor	98.39%	Unkown
HY-15336	AG 555	Inhibitor	≥98.0%	Unkown
HY-144304	PROTAC EGFR degrader 2	Inhibitor	95.61%	Unkown
HY-112345	PD-089828	Inhibitor	98.07%	Unkown
HY-108016	Peruvoside	Inhibitor	99.32%	Unkown
HY-117155	PKI-166	Inhibitor	99.58%	Unkown
HY-112420	EGFR/ErbB-2/ErbB-4 inhibitor-2	Inhibitor	99.45%	Unkown
HY-12008S	Erlotinib-d6 hydrochloride	Inhibitor	98.13%	Unkown
HY-P1828A	EGFRvIII peptide (PEPvIII) TFA		98.73%	Unkown
HY-113599	Isoprocurcumenol	Activator	95.41%	Unkown
HY-15772S	Osimertinib-d6	Inhibitor	99.97%	Unkown
HY-126320	EGFR-IN-8	Inhibitor	98.01%	Unkown
HY-111415	EGFR-IN-5	Inhibitor	99.49%	Unkown
HY-100214	EAI001	Inhibitor	99.88%	Unkown
HY-15769	WHI-P180	Inhibitor	99.84%	Unkown
HY-155079	DZD1516		98.31%	Unkown
HY-147183A	JBJ-09-063 TFA	Inhibitor	99.64%	Unkown
HY-136430	JCN037	Inhibitor	99.76%	Unkown
HY-164762	Trastuzumab rezetecan	Inhibitor	98.61%	Unkown
HY-149530	EGFR-IN-86	Inhibitor	99.92%	Unkown
HY-108484	PP 3	Inhibitor	98.78%	Unkown
HY-153901	PROTAC EGFR degrader 8	Inhibitor	98.90%	Unkown
HY-13984	Mutant EGFR inhibitor	Inhibitor	99.51%	Unkown
HY-10261S	Afatinib-d6	Inhibitor	≥99.0%	Unkown
HY-135805B	(Rac)-JBJ-04-125-02 acetate		96.58%	Unkown
HY-101042	AG-494	Inhibitor	99.31%	Unkown
HY-101960A	Tyrphostin A51	Inhibitor	≥99.0%	Unkown
HY-15772S1	Osimertinib-13C,d3		99.14%	Unkown
HY-142512	EGFR-IN-24	Inhibitor	98.71%	Unkown
HY-163094	EGFR-IN-95	Inhibitor	98.76%	Unkown
HY-133780	Afatinib impurity 11	Inhibitor	99.10%	Unkown
HY-131864	SJF-1528	Degrader	99.71%	Unkown
HY-157480	EGFR/AURKB-IN-1	Inhibitor	99.43%	Unkown
HY-W087187	DOTAGA-anhydride		99.80%	Unkown
HY-13897	CNX-2006	Inhibitor	98.42%	Unkown
HY-131864A	SJF-1528 hemihydrate	Degrader	98.90%	Unkown
HY-135805A	(Rac)-JBJ-04-125-02	Inhibitor	/	Unkown
HY-171135	Cetuximab MMAE	Inhibitor	/	Unkown
HY-115716	EGFR-IN-17	Inhibitor	98.18%	Unkown
HY-141481	DP-C-4	Inhibitor	98.15%	Unkown
HY-50898S	Lapatinib-d4	Inhibitor	99.02%	Unkown
HY-P10224A	G7-18NATE TFA		98.59%	Unkown
HY-152098	HX103	Inhibitor	99.10%	Unkown
HY-118532	Tyrphostin AG30	Inhibitor	99.70%	Unkown
HY-156284	EGFR-IN-89	Inhibitor	98.75%	Unkown
HY-161927	EGFR-TK-IN-4	Inhibitor	99.90%	Unkown
HY-146349	PROTAC EGFR degrader 4	Inhibitor	99.70%	Unkown
HY-101429	RG13022	Inhibitor	96.74%	Unkown
HY-161536	PROTAC EGFR degrader 9	Inhibitor	98.35%	Unkown
HY-100499	Tyrphostin AG 528	Inhibitor	≥98.0%	Unkown
HY-161633	PROTAC EGFR degrader 11	Degrader	99.20%	Unkown
HY-100923	H-9 Dihydrochloride	Inhibitor	98.98%	Unkown
HY-RS04472	ERBB4 Human Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-151159	DHFR-IN-4	Inhibitor	99.19%	Unkown
HY-161275	BI-4732	Inhibitor	99.30%	Unkown
HY-W013857	Lavendustin C	Inhibitor	98.32%	Unkown
HY-P1855	HER2/neu (654-662) GP2		98.26%	Unkown
HY-161537	EGFR ligand-9	Inhibitor	98.80%	Unkown
HY-103441	JNJ28871063 hydrochloride	Inhibitor	98.36%	Unkown
HY-138072	EMI1	Inhibitor	99.78%	Unkown
HY-U00002	ZD-4190	Inhibitor	98.08%	Unkown
HY-147858	PROTAC EGFR degrader 7	Inhibitor	99.99%	Unkown
HY-161126	EGFR-IN-98	Inhibitor	99.12%	Unkown
HY-101426	RG14620	Inhibitor	98.09%	Unkown
HY-N6577	Astragaloside VI		99.95%	Unkown
HY-153111	EGFR/HER2-IN-9	Inhibitor	98.73%	Unkown
HY-149889	EGFR-IN-78	Inhibitor	99.57%	Unkown
HY-163428	Perzebertinib	Inhibitor	/	Unkown
HY-50895S	Gefitinib-d8	Inhibitor	98.42%	Unkown
HY-19617	EGFR-IN-1	Inhibitor	/	Unkown
HY-100962	(E)-AG 99	Inhibitor	98.36%	Unkown
HY-128862	EGFR-IN-7	Inhibitor	99.76%	Unkown
HY-19617A	EGFR-IN-1 hydrochloride	Inhibitor	/	Unkown
HY-145960	MC-Val-Cit-PAB-Amide-TLR7 agonist 4	Agonist	99.39%	Unkown
HY-119944	JND3229	Inhibitor	99.78%	Unkown
HY-153110	Larotinib	Inhibitor	99.50%	Unkown
HY-132842A	(S)-Sunvozertinib	Inhibitor	99.14%	Unkown
HY-147941	MS9427	Degrader	95.29%	Unkown
HY-147219	SIAIS164018	Inhibitor	/	Unkown
HY-138627	AST5902	Inhibitor	/	Unkown
HY-147183	JBJ-09-063	Inhibitor	/	Unkown
HY-130608	Mutated EGFR-IN-3	Inhibitor	/	Unkown
HY-100064	O-Desmethyl gefitinib	Inhibitor	99.40%	Unkown
HY-144677	pan-HER-IN-2	Inhibitor	98.10%	Unkown
HY-161618	MJ04	Inhibitor	98.08%	Unkown
HY-P3744	pp60v-src Autophosphorylation site		99.93%	Unkown
HY-143337	EGFR-IN-47	Inhibitor	96.01%	Unkown
HY-101006	Methyl 2,5-dihydroxycinnamate	Inhibitor	99.70%	Unkown
HY-W013852	PKC-IN-6	Inhibitor	99.63%	Unkown
HY-126319	SU5204	Inhibitor	99.46%	Unkown
HY-111452	EGFR-IN-85	Inhibitor	/	Unkown
HY-101007A	(+)-Tyrphostin B44	Inhibitor	97.01%	Unkown
HY-164307	Pebezertinib	Inhibitor	99.56%	Unkown
HY-168438	ERBB agonist-1	Agonist	99.16%	Unkown
HY-164702	BL-B01D1	Inhibitor	99.53%	Unkown
HY-101522	CHMFL-EGFR-202	Inhibitor	99.75%	Unkown
HY-157413	YS-67	Inhibitor	99.41%	Unkown
HY-149636	Multi-target kinase inhibitor 2	Inhibitor	99.82%	Unkown
HY-157579	MS154N		99.30%	Unkown
HY-10531	ARRY-380 analog	Inhibitor	99.19%	Unkown
HY-W423595	BEBT-109	Inhibitor	98.72%	Unkown
HY-13272S2	Dacomitinib-d10 dihydrochloride	Inhibitor	≥95.0%	Unkown
HY-19985A	(3S,4S)-PF-06459988		98.97%	Unkown
HY-50895S1	Gefitinib-d6	Inhibitor	≥98.0%	Unkown
HY-19617B	EGFR-IN-1 TFA	Inhibitor	99.38%	Unkown
HY-P4082	ErbB-2-binding peptide		99.83%	Unkown
HY-135805	JBJ-04-125-02	Inhibitor	/	Unkown
HY-14347	EBE-A22	Control	99.76%	Unkown
HY-150610	EGFR-IN-69	Inhibitor	99.58%	Unkown
HY-161408	GePhos1		/	Unkown
HY-P2673	Lys-Arg-Thr-Leu-Arg-Arg		/	Unkown
HY-12872B	Nazartinib S-enantiomer		98.66%	Unkown
HY-158149	T-1-PMPA	Inhibitor	99.70%	Unkown
HY-162254	EGFR/ACK1-IN-1	Inhibitor	/	Unkown
HY-50896S	Erlotinib-d6	Inhibitor	/	Unkown
HY-155005	EGFR mutant-IN-2	Inhibitor	≥97.0%	Unkown
HY-P2503	EGFR Protein Tyrosine Kinase Substrate		99.72%	Unkown
HY-12806	AG1557	Inhibitor	99.54%	Unkown
HY-158310	SOS1/EGFR-IN-1	Inhibitor	99.54%	Unkown
HY-155285	YS-363	Inhibitor	99.52%	Unkown
HY-155358	Os30	Inhibitor	98.34%	Unkown
HY-103439	GW583340 dihydrochloride	Inhibitor	/	Unkown
HY-P2673A	Lys-Arg-Thr-Leu-Arg-Arg acetate		/	Unkown
HY-13450	ZM 449829	Inhibitor	99.73%	Unkown
HY-138751A	limertinib diTFA	Inhibitor	≥98.0%	Unkown
HY-101756	SDZ281-977		98.00%	Unkown
HY-100520	EGFR-IN-2	Inhibitor	/	Unkown
HY-135914	JBJ-02-112-05	Inhibitor	/	Unkown
HY-142283	Dosimertinib	Inhibitor	/	Unkown
HY-132883	EGFR/CSC-IN-1	Inhibitor	/	Unkown
HY-163354	EGFR-IN-103	Inhibitor	/	Unkown
HY-131067	EMI56	Inhibitor	99.72%	Unkown
HY-143734	HER2-IN-6		/	Unkown
HY-128860	Mutated EGFR-IN-2	Inhibitor	/	Unkown
HY-144048	EGFR-IN-31		/	Unkown
HY-115951	EGFR/HER2-IN-2	Inhibitor	/	Unkown
HY-125841	EGFR mutant-IN-1	Inhibitor	/	Unkown
HY-131066	EMI48	Inhibitor	99.02%	Unkown
HY-147407	Imbotolimod	Inhibitor	/	Unkown
HY-138746	EGFR-IN-15	Inhibitor	/	Unkown
HY-147303	Sacibertinib	Inhibitor	/	Unkown
HY-10407G	SU 5402 (GMP)	Inhibitor	/	Unkown
HY-150782	UNC-CA359	Inhibitor	/	Unkown
HY-144053	EGFR-IN-36	Inhibitor	/	Unkown
HY-146170	Anticancer agent 69	Inhibitor	/	Unkown
HY-131710	PDE5-IN-3	Inhibitor	/	Unkown
HY-15268	PP487	Inhibitor	/	Unkown
HY-P10793	Cyclic(YCDGFYACYMDV)	Inhibitor	/	Unkown
HY-155118	EGFR-IN-81	Inhibitor	/	Unkown
HY-146210	EGFR-IN-50	Inhibitor	/	Unkown
HY-100064S1	O-Desmethyl gefitinib-d6	Inhibitor	/	Unkown
HY-157912	EGFR-IN-102	Inhibitor	/	Unkown
HY-162482	EGFR kinase inhibitor 5	Inhibitor	/	Unkown
HY-146136	EGFR-IN-56	Inhibitor	/	Unkown
HY-101959	Tyrphostin AG213	Inhibitor	/	Unkown
HY-155178	Antiproliferative agent-34	Inhibitor	/	Unkown
HY-139884	EGFR-IN-18	Inhibitor	/	Unkown
HY-10368	EGFR/VEGFR2-IN-4	Inhibitor	/	Unkown
HY-161067	EGFR-IN-96	Inhibitor	/	Unkown
HY-164503	Neptinib	Inhibitor	/	Unkown
HY-147798	EGFR/HER2/CDK9-IN-3	Inhibitor	/	Unkown
HY-RS04467	Erbb2 Mouse Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-164392	TAS-121	Inhibitor	/	Unkown
HY-172470	DSPE-PEG2000-GE11		/	Unkown
HY-151162	HER2-IN-12	Inhibitor	/	Unkown
HY-162602	EGFR-IN-115	Inhibitor	/	Unkown
HY-144605	PROTAC EGFR degrader 3	Inhibitor	97.39%	Unkown
HY-161146	EGFR-IN-100	Inhibitor	/	Unkown
HY-147862	EGFR-IN-62	Inhibitor	/	Unkown
HY-146228	HSP90-IN-13	Inhibitor	/	Unkown
HY-153557A	HER2-IN-14	Inhibitor	/	Unkown
HY-19730A	Olmutinib hydrochloride	Inhibitor	/	Unkown
HY-162323	EGFR-IN-106	Inhibitor	/	Unkown
HY-P5742	ELAAWCRWGFLLALLPPGIAG		/	Unkown
HY-143323	HER2-IN-9	Inhibitor	/	Unkown
HY-149846	SIQ17	Inhibitor	/	Unkown
HY-100064S	O-Desmethyl gefitinib-d8	Inhibitor	99.84%	Unkown
HY-10261E	(R)-Afatinib	Inhibitor	/	Unkown
HY-170559	EGFR-IN-141	Inhibitor	/	Unkown
HY-151981	EGFR-IN-74	Inhibitor	/	Unkown
HY-103437	EGFR-IN-80	Inhibitor	/	Unkown
HY-162360	EGFR-IN-109	Inhibitor	/	Unkown
HY-158178	EGFR T790M/L858R-IN-7	Inhibitor	/	Unkown
HY-172469	DSPE-PEG1000-GE11		/	Unkown
HY-149556	MTX-241F	Inhibitor	/	Unkown
HY-149407	Multi-kinase-IN-4	Inhibitor	/	Unkown
HY-163860	EGFR-TK-IN-3	Inhibitor	/	Unkown
HY-138627B	AST5902 mesylate	Inhibitor	/	Unkown
HY-N3634	Corylifol C		/	Unkown
HY-163000	EGFR-IN-129	Inhibitor	/	Unkown
HY-P2548	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated		/	Unkown
HY-168433	LSD1/EGFR-IN-1	Inhibitor	/	Unkown
HY-115952	EGFR/HER2-IN-3	Inhibitor	/	Unkown
HY-155079A	(R)-DZD1516	Control	98.80%	Unkown
HY-149517	EGFR/BRAFV600E-IN-2	Inhibitor	/	Unkown
HY-126850	4-Epidoxycycline		/	Unkown
HY-162890	EGFR-IN-122	Inhibitor	/	Unkown
HY-144056	EGFR-IN-39	Inhibitor	/	Unkown
HY-168627	EGFR-IN-135	Inhibitor	/	Unkown
HY-144054	EGFR-IN-37	Inhibitor	/	Unkown
HY-153557	HER2-IN-13	Inhibitor	/	Unkown
HY-173146	EGFR-IN-153	Inhibitor	/	Unkown
HY-146471	EGFR-IN-51	Inhibitor	/	Unkown
HY-162483	EGFR kinase inhibitor 6	Inhibitor	/	Unkown
HY-161603	EGFR/HER2-IN-14	Inhibitor	/	Unkown
HY-168064	EGFR-IN-124	Inhibitor	/	Unkown
HY-144441	NSC81111	Inhibitor	/	Unkown
HY-163657	HER2-IN-20	Inhibitor	/	Unkown
HY-162332	EGFR-PK/JNK-2-IN-1	Inhibitor	/	Unkown
HY-160682	EGFR/HER2-IN-12	Inhibitor	/	Unkown
HY-164489	KU004	Inhibitor	/	Unkown
HY-147796	EGFR/HER2/CDK9-IN-1	Inhibitor	/	Unkown
HY-153856A	TAS2940 fumarate	Inhibitor	/	Unkown
HY-162300	EGFR kinase inhibitor 4	Inhibitor	/	Unkown
HY-172091	CZY43	Degrader	/	Unkown
HY-169427	FRF-06-057	Inhibitor	/	Unkown
HY-P10659	Self-assembling peptide pY1		/	Unkown
HY-144444	NSC381467	Inhibitor	/	Unkown
HY-159101	EP26	Inhibitor	/	Unkown
HY-145824	EGFR-IN-43	Inhibitor	/	Unkown
HY-13524A	AG-1478 hydrochloride	Inhibitor	/	Unkown
HY-151154	EGFR/HER2/DHFR-IN-1	Inhibitor	/	Unkown
HY-168514	SOS1/EGFR-IN-2	Inhibitor	/	Unkown
HY-120857	BPIQ-II hydrochloride	Inhibitor	/	Unkown
HY-173038	EGFR-IN-151	Inhibitor	/	Unkown
HY-147997	EGFR-IN-68	Inhibitor	/	Unkown
HY-161968	EGFR/PI3Kα-IN-1	Inhibitor	/	Unkown
HY-P10224	G7-18NATE		/	Unkown
HY-168623	EGFR-IN-134	Inhibitor	/	Unkown
HY-156639	EGFR/ErbB-2 inhibitor-1	Inhibitor	/	Unkown
HY-156912	Tyrosine kinase-IN-7	Inhibitor	99.25%	Unkown
HY-110406	13(S)-HPODE	Activator	/	Unkown
HY-171252	EGFR-IN-145	Inhibitor	/	Unkown
HY-155227	ALK/EGFR-IN-1	Inhibitor	/	Unkown
HY-161632	PROTAC EGFR degrader 10	Degrader	/	Unkown
HY-115933	EGFR/BRAF-IN-1	Inhibitor	/	Unkown
HY-13050A	Sapitinib fumarate	Inhibitor	/	Unkown
HY-164988	TX2-120-1	Degrader	/	Unkown
HY-13314A	Tesevatinib tosylate	Inhibitor	/	Unkown
HY-152144	EGFR-IN-75	Inhibitor	/	Unkown
HY-149695	EGFR-IN-91	Inhibitor	/	Unkown
HY-145844	EGFR-IN-44	Inhibitor	/	Unkown
HY-146474	EGFR-IN-54	Inhibitor	/	Unkown
HY-162964	EGFR-IN-126	Inhibitor	/	Unkown
HY-168876	AZ14240475	Inhibitor	/	Unkown
HY-143445	EGFR-IN-48	Inhibitor	/	Unkown
HY-146132	EGFR-IN-55	Inhibitor	/	Unkown
HY-112405	BPIQ-I	Inhibitor	/	Unkown
HY-149401	EGFR-IN-82	Inhibitor	/	Unkown
HY-143901	EGFR-IN-40	Inhibitor	/	Unkown
HY-170543	Dual Galectin-3/EGFR-IN-1	Inhibitor	/	Unkown
HY-13595R	Chrysophanol (Standard)	Inhibitor	/	Unkown
HY-171265	MRG003	Degrader	/	Unkown
HY-158018	EGFR-TK-IN-2	Inhibitor	/	Unkown
HY-RS04474	Erbb4 Rat Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-172156	EGFR-TK-IN-5	Inhibitor	/	Unkown
HY-18957A	rel-Lifirafenib	Control	/	Unkown
HY-149632	EGFR/HER2/DHFR-IN-2	Inhibitor	/	Unkown
HY-168492	TrxR/EGFR-IN-1	Inhibitor	/	Unkown
HY-142678	EGFR-IN-21	Inhibitor	/	Unkown
HY-163723	EGFR-IN-116	Inhibitor	/	Unkown
HY-110328	PKI-166 hydrochloride	Inhibitor	/	Unkown
HY-163418	HER2-IN-17	Inhibitor	/	Unkown
HY-113549	Erbstatin	Inhibitor	/	Unkown
HY-155074	EGFR-IN-79	Inhibitor	/	Unkown
HY-163726	GLUT1/EGFR-IN-1	Inhibitor	99.75%	Unkown
HY-168173	EGFR-IN-130	Inhibitor	/	Unkown
HY-139997	DDC-01-163	Degrader	/	Unkown
HY-152019	EGFR/C797S-IN-1	Inhibitor	/	Unkown
HY-101960	(Z)-Tyrphostin A51	Inhibitor	/	Unkown
HY-116138	RG-14467	Inhibitor	/	Unkown
HY-143729	EGFR-IN-29	Inhibitor	/	Unkown
HY-142681	EGFR-IN-28	Inhibitor	/	Unkown
HY-152169	BIHC	Inhibitor	/	Unkown
HY-116277	Z118332870	Inhibitor	/	Unkown
HY-144445	NSC114126	Inhibitor	/	Unkown
HY-155227S	ALK/EGFR-IN-1-d5	Inhibitor	/	Unkown
HY-164718	Sevabertinib	Inhibitor	/	Unkown
HY-W174279	Tyrphostin 8	Inhibitor	≥98.0%	Unkown
HY-P1085	Epidermal Growth Factor Receptor Peptide (985-996)	Chemical	/	Unkown
HY-108931	AG 1406	Inhibitor	99.03%	Unkown
HY-163419	HER2-IN-18	Inhibitor	/	Unkown
HY-15772S3	Asandeutertinib	Inhibitor	/	Unkown
HY-144055	EGFR-IN-38	Inhibitor	/	Unkown
HY-147995	EGFR-IN-64	Inhibitor	/	Unkown
HY-156470	Multi-kinase-IN-6	Inhibitor	/	Unkown
HY-159512	EGFR kinase inhibitor 7	Inhibitor	/	Unkown
HY-162062	EGFR WT/T790M/L858R-IN-1	Inhibitor	/	Unkown
HY-149633	EGFR/HER2/DHFR-IN-3	Inhibitor	/	Unkown
HY-163722	EGFR/DHFR-IN-1	Inhibitor	/	Unkown
HY-161320	EGFR-IN-105	Inhibitor	/	Unkown
HY-163377	AZ5385	Inhibitor	/	Unkown
HY-170968	EGFR-IN-150	Inhibitor	/	Unkown
HY-168427	Avitinib maleate dihydrate	Inhibitor	/	Unkown
HY-163663	AZ14133346	Inhibitor	/	Unkown
HY-13272S3	Dacomitinib-d10	Inhibitor	/	Unkown
HY-144794	EGFR-IN-46	Inhibitor	/	Unkown
HY-147802	EGFR-IN-59	Inhibitor	/	Unkown
HY-112474	Tyrphostin AG 112	Inhibitor	98.55%	Unkown
HY-164413	CLM3	Inhibitor	/	Unkown
HY-172179	EGFR/VEGFR2-IN-5	Inhibitor	/	Unkown
HY-110039	BIBX 1382 dihydrochloride	Inhibitor	/	Unkown
HY-164056	EGFR T790M/L858R-IN-8	Inhibitor	99.20%	Unkown
HY-158016	Antiproliferative agent-49	Inhibitor	/	Unkown
HY-172111	EGFR-IN-144	Inhibitor	/	Unkown
HY-169982	EGFR-IN-136	Inhibitor	/	Unkown
HY-50898S2	Lapatinib-d5	Inhibitor	/	Unkown
HY-149518	EGFR/BRAFV600E-IN-3	Inhibitor	/	Unkown
HY-169428	EGFR-IN-138		/	Unkown
HY-142680	EGFR-IN-23	Inhibitor	/	Unkown
HY-173218	anti-NSCLC agent-1	Inhibitor	/	Unkown
HY-142283BS	N-Desmethyl dosimertinib-d5		/	Unkown
HY-141486A	PROTAC PARP/EGFR ligand 1		/	Unkown
HY-160564	ZNL-0056	Inhibitor	/	Unkown
HY-RS04210	Egfr Mouse Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-156457	EGFR-IN-90	Inhibitor	/	Unkown
HY-170932	EGFR/COX-2-IN-1	Inhibitor	/	Unkown
HY-RS04471	Erbb3 Rat Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-168112	EGFR-IN-127	Inhibitor	/	Unkown
HY-147996	EGFR-IN-67	Inhibitor	/	Unkown
HY-123891	NS-062	Inhibitor	/	Unkown
HY-157398	EGFR T790M/L858R-IN-3	Inhibitor	/	Unkown
HY-168170	EGFR/VEGFR2-IN-2	Inhibitor	/	Unkown
HY-170438	EGFR-IN-139		/	Unkown
HY-146238	EGFR/HER2/TS-IN-1	Inhibitor	/	Unkown
HY-10261S1	Afatinib-d4	Inhibitor	/	Unkown
HY-146423	PROTAC EGFR degrader 6	Inhibitor	/	Unkown
HY-162788	EGFR-IN-121	Inhibitor	/	Unkown
HY-168968S	ZJY-54	Inhibitor	/	Unkown
HY-155969	EGFR-IN-83	Inhibitor	/	Unkown
HY-164490	LS-106	Inhibitor	/	Unkown
HY-146782	EGFR-IN-49	Inhibitor	/	Unkown
HY-172471	DSPE-PEG5000-GE11		/	Unkown
HY-164694	Emupertinib	Inhibitor	/	Unkown
HY-RS04473	Erbb4 Mouse Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-163420	HER2-IN-16	Inhibitor	/	Unkown
HY-173164	EGFR/BRAFV600E-IN-4	Inhibitor	/	Unkown
HY-169216	Multi-target kinase inhibitor 3	Inhibitor	/	Unkown
HY-170787	TZEP7	Inhibitor	/	Unkown
HY-RS04469	ERBB3 Human Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-18298	PD 173955 analog 1	Inhibitor	/	Unkown
HY-159519	EGFR/HER2-IN-16	Inhibitor	/	Unkown
HY-161045	T-1-DOCA	Inhibitor	/	Unkown
HY-156116	EGFR/CDK2-IN-4	Inhibitor	/	Unkown
HY-161891	EGFR/Akt-IN-1	Inhibitor	/	Unkown
HY-147994	EGFR/HER2-IN-5	Inhibitor	/	Unkown
HY-162148	HNPMI	Inhibitor	99.57%	Unkown
HY-168151	EGFR-IN-128	Inhibitor	/	Unkown
HY-RS04211	Egfr Rat Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-170665	EGFR T790M/L858R-IN-9	Inhibitor	/	Unkown
HY-150781	EGFR-IN-71	Inhibitor	/	Unkown
HY-127067	Yuanhuadin	Inhibitor	/	Unkown
HY-W008914	(E/Z)-CP-724714	Inhibitor	/	Unkown
HY-157399	EGFR/HER2-IN-10	Inhibitor	/	Unkown
HY-157324	EGFR-IN-94	Inhibitor	/	Unkown
HY-P1828	EGFRvIII peptide (PEPvIII)		/	Unkown
HY-161785	EGFR-IN-117	Inhibitor	/	Unkown
HY-172160	HER2-IN-21	Inhibitor	/	Unkown
HY-P5745A	TYVPANASL TFA		/	Unkown
HY-149344	Anticancer agent 133	Inhibitor	/	Unkown
HY-172104	EGFR-IN-143	Inhibitor	/	Unkown
HY-163402	EGFR-IN-108 chloride	Inhibitor	/	Unkown
HY-151882	EGFR-IN-73	Inhibitor	/	Unkown
HY-155200	EGFR-IN-84	Inhibitor	/	Unkown
HY-146472	EGFR-IN-52	Inhibitor	/	Unkown
HY-151158	EGFR/HER2-IN-7	Inhibitor	/	Unkown
HY-P10569	Biotin HER-2 substrate peptide		/	Unkown
HY-129510	4-Methyl erlotinib	Inhibitor	/	Unkown
HY-118175	RG 14921	Inhibitor	/	Unkown
HY-161781	HVH-2930	Inhibitor	/	Unkown
HY-18213	EGFR-IN-9	Inhibitor	98.84%	Unkown
HY-P10792	HER2-targeted peptide H6F		/	Unkown
HY-158176	EGFR T790M/L858R-IN-5	Inhibitor	/	Unkown
HY-110333	BMS-599626 dihydrochloride	Inhibitor	/	Unkown
HY-168655	EGFR/VEGFR2-IN-3	Inhibitor	/	Unkown
HY-137028	2′-Thioadenosine	Inhibitor	/	Unkown
HY-164387A	Sutetinib maleate	Inhibitor	/	Unkown
HY-B0794S	AZ7550-d5	Inhibitor	/	Unkown
HY-161136	EGFR/STAT3-IN-1	Inhibitor	/	Unkown
HY-RS04466	ERBB2 Human Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-168469	EGFR-IN-148	Inhibitor	/	Unkown
HY-144097	HER2-IN-8	Inhibitor	/	Unkown
HY-147741	DPPY	Inhibitor	/	Unkown
HY-158175	EGFR T790M/L858R-IN-4	Inhibitor	/	Unkown
HY-151156	EGFR/HER2-IN-6	Inhibitor	/	Unkown
HY-RS04470	Erbb3 Mouse Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-153856	TAS2940	Inhibitor	/	Unkown
HY-144050	EGFR-IN-33	Inhibitor	/	Unkown
HY-151377	RET-IN-19	Inhibitor	/	Unkown
HY-157526	EGFR-TK-IN-1	Inhibitor	/	Unkown
HY-168073	EGFR/VEGFR2-IN-1	Inhibitor	/	Unkown
HY-161866	EGFR-IN-118	Inhibitor	/	Unkown
HY-147797	EGFR/HER2/CDK9-IN-2	Inhibitor	/	Unkown
HY-121828	TX-1123	Inhibitor	/	Unkown
HY-172110	Apoptosis inducer 35	Inhibitor	/	Unkown
HY-144044	EGFR-IN-30	Inhibitor	/	Unkown
HY-157432	EGFR-IN-97	Inhibitor	/	Unkown
HY-146422	PROTAC EGFR degrader 5	Inhibitor	/	Unkown
HY-157994	EGFR WT/T790M-IN-2	Inhibitor	/	Unkown
HY-147826	EGFR-IN-60	Inhibitor	/	Unkown
HY-144676	pan-HER-IN-1	Inhibitor	/	Unkown
HY-157402	Topoisomerase II/EGFR-IN-1		/	Unkown
HY-100663	Gefitinib impurity 2		99.56%	Unkown
HY-153744	JGK-068S	Inhibitor	/	Unkown
HY-169408	EGFR-IN-137	Inhibitor	/	Unkown
HY-162099	VEGFR-IN-4	Inhibitor	/	Unkown
HY-158153	EGFR-IN-108	Inhibitor	/	Unkown
HY-114535	Jaceidin	Inhibitor	/	Unkown
HY-169568	EGFR-IN-147	Inhibitor	/	Unkown
HY-147992	EGFR/HER2-IN-4	Inhibitor	/	Unkown
HY-146138	EGFR-IN-57	Inhibitor	/	Unkown
HY-156033	EGFR-IN-88	Inhibitor	/	Unkown
HY-145867	EGFR-IN-45	Inhibitor	/	Unkown
HY-10261AS	Afatinib-d6 dimaleate	Inhibitor	/	Unkown
HY-161269	EGFR-IN-101	Inhibitor	/	Unkown
HY-116504	WB-308	Inhibitor	/	Unkown
HY-160613	EGFR/HER2-IN-11	Inhibitor	/	Unkown
HY-173314	EGFR-IN-155	Inhibitor	/	Unkown
HY-12008S1	Erlotinib-13C6 hydrochloride		/	Unkown
HY-161031	EGFR-IN-93	Inhibitor	/	Unkown
HY-169308	EGFR-IN-132	Inhibitor	/	Unkown
HY-149824	EGFR T790M/L858R-IN-2	Inhibitor	99.66%	Unkown
HY-163880	EGFR-IN-119	Inhibitor	/	Unkown
HY-137786	EGFR-IN-16	Inhibitor	/	Unkown
HY-169346	Pred17	Inhibitor	/	Unkown
HY-164399	SST0116CL1	Degrader	/	Unkown
HY-161030	EGFR-IN-92	Inhibitor	/	Unkown
HY-162623	EGFR/HER2-IN-15	Inhibitor	/	Unkown
HY-161602	EGFR/HER2-IN-13	Inhibitor	/	Unkown
HY-156741	EGFR-IN-87	Inhibitor	/	Unkown
HY-163006	EGFR/c-Met-IN-1	Inhibitor	/	Unkown
HY-147248	Opadotina	Inhibitor	/	Unkown
HY-50898S1	Lapatinib-d7 dihydrochloride	Inhibitor	/	Unkown
HY-160068	2-2(t) aptamer sodium	Chemical	/	Unkown
HY-163371	EGFR WT/T790M-IN-1	Inhibitor	/	Unkown
HY-135216	Antiproliferative agent-54	Inhibitor	/	Unkown
HY-147860	EGFR-IN-61	Inhibitor	/	Unkown
HY-144051	EGFR-IN-34	Inhibitor	/	Unkown
HY-402309	IGF-1R modulator 1	Modulator	/	Unkown
HY-169309	EGFR-IN-133	Inhibitor	/	Unkown
HY-164387	Sutetinib	Inhibitor	/	Unkown
HY-151573	EGFR/CDK2-IN-1	Inhibitor	/	Unkown
HY-143246	EGFR kinase inhibitor 1	Inhibitor	/	Unkown
HY-P10686	CH401 peptide		/	Unkown
HY-147825	EGFR/BRAFV600E-IN-1	Inhibitor	/	Unkown
HY-150905	EGFR ligand-2	Inhibitor	/	Unkown
HY-142283CS	N-Methyl-dosimertinib-d5		/	Unkown
HY-100636	Gefitinib N-oxide	Inhibitor	/	Unkown
HY-167948	Dacomitinib metabolite M1/2	Inhibitor	/	Unkown
HY-156097	Anticancer agent 158	Inhibitor	/	Unkown
HY-170928	DA-0157	Inhibitor	/	Unkown
HY-172429	Enozertinib	Inhibitor	/	Unkown
HY-146127	Grb2 SH2 domain inhibitor 1	Inhibitor	/	Unkown
HY-143733	HER2-IN-5	Inhibitor	/	Unkown
HY-170661	EGFR-IN-142	Inhibitor	/	Unkown
HY-163453	HER2-IN-19	Inhibitor	/	Unkown
HY-142517	EGFR-IN-25	Inhibitor	/	Unkown
HY-147967	EGFR-IN-63	Inhibitor	/	Unkown
HY-146154	EGFR-IN-58	Inhibitor	/	Unkown
HY-172414	Andamertinib	Inhibitor	/	Unkown
HY-161145	EGFR/microtubule-IN-1	Inhibitor	/	Unkown
HY-161923	EGFR-IN-120	Inhibitor	/	Unkown
HY-144052	EGFR-IN-35	Inhibitor	/	Unkown
HY-158177	EGFR T790M/L858R-IN-6	Inhibitor	/	Unkown
HY-161731	DS08701581	Inhibitor	/	Unkown
HY-163417	HER2-IN-15	Inhibitor	/	Unkown
HY-146473	EGFR-IN-53	Inhibitor	/	Unkown
HY-161319	EGFR-IN-104	Inhibitor	/	Unkown
HY-100636A	Gefitinib N-oxide hydrochloride	Inhibitor	/	Unkown
HY-RS04209	EGFR Human Pre-designed siRNA Set A	Inhibitor	/	Unkown
HY-173188	EGFR-IN-154	Inhibitor	/	Unkown
HY-168577	KRAS G12D inhibitor 25	Degrader	/	Unkown
HY-123035	Gamendazole	Inhibitor	/	Unkown
HY-101958	Tyrphostin 25	Inhibitor	99.00%	Unkown
HY-158154	EGFR-IN-110	Inhibitor	/	Unkown
HY-157166	EGFR kinase inhibitor 2	Inhibitor	/	Unkown
HY-144049	EGFR-IN-32	Inhibitor	/	Unkown
HY-P5742A	ELAAWCRWGFLLALLPPGIAG TFA		/	Unkown
HY-168559	EGFR-IN-131	Inhibitor	/	Unkown
HY-146239	EGFR/HER2/TS-IN-2	Inhibitor	/	Unkown
HY-163434	PRMT5/EGFR-IN-1	Inhibitor	/	Unkown
HY-145823	EGFR-IN-42	Inhibitor	/	Unkown
HY-170497	EGFR-IN-140	Inhibitor	/	Unkown
HY-156114	EGFR/CDK2-IN-2	Inhibitor	/	Unkown
HY-144760	EGFR-IN-3	Inducer	/	Unkown
HY-163632	EGFR-IN-112	Inhibitor	/	Unkown
HY-142679	EGFR-IN-22	Inhibitor	/	Unkown
HY-162891	EGFR-IN-123	Inhibitor	/	Unkown
HY-P5258	Oligopeptide-41	Inducer	/	Unkown
HY-151161	EGFR/HER2-IN-8	Inhibitor	/	Unkown
HY-B0793S1	AZ-5104-d2	Inhibitor	/	Unkown
HY-149275	PKM2/PDK1-IN-1	Inhibitor	/	Unkown
HY-151048	JBJ-07-149	Inhibitor	/	Unkown
HY-142519	EGFR-IN-27	Inhibitor	/	Unkown
HY-162881	DS06652923	Inhibitor	/	Unkown
HY-143874	HER2-IN-7	Inhibitor	/	Unkown
HY-50896S1	Erlotinib-13C6	Inhibitor	/	Unkown
HY-50898S3	Lapatinib-d4-1	Inhibitor	/	Unkown
HY-156115	EGFR/CDK2-IN-3	Inhibitor	/	Unkown
HY-15769A	WHI-P180 hydrochloride	Inhibitor	/	Unkown
HY-163396	EGFR-IN-107	Inhibitor	/	Unkown
HY-164919	Calotatug ginistinag	Inhibitor	/	Unkown
HY-158828	SSO111 sodium		/	Unkown
HY-19909A	NRC-2694-A	Inhibitor	/	Unkown
HY-50895S2	Gefitinib-d3	Inhibitor	/	Unkown
HY-158829	SSOe26 sodium		/	Unkown
HY-135725	D-69491 hydrochloride	Inhibitor	/	Unkown
HY-156872	MTX-216	Inhibitor	/	Unkown
HY-138916	PF-06672131	Inhibitor	/	Unkown
HY-117523	(Z)-RG-13022	Inhibitor	/	Unkown
HY-171443	Lyso-Monosialoganglioside GM3	Inhibitor	/	Unkown
HY-169948	BML-265	Inhibitor	/	Unkown
HY-N14640	Paeciloquinone F	Inhibitor	/	Unkown
HY-110045	ZM-306416 hydrochloride	Inhibitor	/	Unkown
HY-32721S	Neratinib-d6	Inhibitor	/	Unkown
HY-P10648	Herceptide		/	Unkown
HY-50896S2	Erlotinib-d4	Inhibitor	/	Unkown
HY-157582	MS39N	Control	/	Unkown
HY-129288	GW837016X	Inhibitor	/	Unkown
HY-N14635	Paeciloquinone A	Inhibitor	/	Unkown
HY-164476	ES-072	Inhibitor	/	Unkown
HY-164763	SHR-A1201	Inhibitor	/	Unkown
HY-164527	Si306	Inhibitor	/	Unkown
HY-169566	EGFR-IN-146	Inhibitor	/	Unkown
HY-103443A	HKI-357 dimaleate	Inhibitor	/	Unkown
HY-135727	PF-6422899	Inhibitor	/	Unkown
HY-N14349	Asterriquinone	Inhibitor	/	Unkown
HY-N14636	Paeciloquinone B	Inhibitor	/	Unkown
HY-16069S	Tucatinib-d6	Inhibitor	/	Unkown
HY-N14638	Paeciloquinone D	Inhibitor	/	Unkown
HY-50898S4	Lapatinib-d7	Inhibitor	/	Unkown
HY-21291	SU-4313	Modulator	99.31%	Unkown
HY-N14637	Paeciloquinone C	Inhibitor	/	Unkown
HY-169570	EGFR-IN-149	Inhibitor	/	Unkown
HY-123766	EGFR-IN-99	Inhibitor	/	Unkown
HY-N14639	Paeciloquinone E	Inhibitor	/	Unkown
HY-114667	Lavendustin C6	Inhibitor	/	Unkown
HY-164464	BPI-15086	Inhibitor	/	Unkown
HY-50898CS	Lapatinib-d4 tosylate	Inhibitor	/	Unkown
HY-W740378	1,2,3,4-Tetrahydro Staurosporin	Inhibitor	/	Unkown
HY-153887	HyT36(-Cl)	Control	/	Unkown
HY-156991	NODAGA-NHS		/	Unkown
HY-169755	Tyrphostin 63	Inhibitor	/	Unkown
HY-168305	EGFR ligand-11		/	Unkown
HY-146262	LDC0496	Inhibitor	/	Unkown

Inhibitory Antibodies (28)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9912A	Pertuzumab (anti-HER2)	Inhibitor	99.10%	Unkown
HY-P99684	Laprituximab	Inhibitor	≥95.0%	Unkown
HY-P990238	Anti-Human/Rat HER2 (neu) Antibody (7.16.4)	Inhibitor	95.00%	Unkown
HY-P99892	Serclutamab		99.97%	Unkown
HY-P990071	Fepixnebart	Inhibitor	96.40%	Unkown
HY-P9S0008	Cetuximab (PBS)	Inhibitor	/	Unkown
HY-P990957	Ficerafusp alfa		/	Unkown
HY-P990909	Calotatug		/	Unkown
HY-P990978	Caxmotabart		/	Unkown
HY-P99888	Pimurutamab		/	Unkown
HY-P990962	Vislarafusp alfa		/	Unkown
HY-P990972	Azerutamig		/	Unkown
HY-P99324	Tomuzotuximab	Inhibitor	/	Unkown
HY-P990698	Umizortamig		/	Unkown
HY-P99948	Etevritamab		/	Unkown
HY-P991159	Ruzaltatug	Inhibitor	/	Unkown
HY-P990408	Anti-ERBB1/EGFR/HER1 Antibody	Inhibitor	/	Unkown
HY-P990695	Lunaxafusp	Inhibitor	/	Unkown
HY-P99558	Timigutuzumab	Inhibitor	/	Unkown
HY-P99406A	Petosemtamab (FUT8-KO)		/	Unkown
HY-P990755	Pamvatamig		/	Unkown
HY-P990055	Nezutatug	Inhibitor	/	Unkown
HY-P99685	Laprituximab emtansine	Inhibitor	/	Unkown
HY-P990913	Dalmitamig		/	Unkown
HY-P990947	Tilatamig		/	Unkown
HY-P9977A	Amivantamab (FUT8-KO)	Inhibitor	/	Unkown
HY-P991090	YH32367	Inhibitor	/	Unkown
HY-P991092	IBI-334	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Egfr	NCBI	NCBI:1956
Canis familiaris	Egfr	NCBI	NCBI:404306
Macaca fascicularis	Egfr	NCBI	NCBI:102138724
Rattus norvegicus	Egfr	NCBI	NCBI:24329
Macaca mulatta	Egfr	NCBI	NCBI:613027

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