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CuAAC

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1677

Inhibitors & Agonists

82

Fluorescent Dye

36

Biochemical Assay Reagents

14

Peptides

23

Natural
Products

48

Isotope-Labeled Compounds

1403

Click Chemistry

120

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16986B
    EPZ011989 hydrochloride
    2 Publications Verification

    		 Histone Methyltransferase Cancer
    EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of <3 nM. EPZ011989 shows anti-tumor activity. EPZ011989 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    EPZ011989 hydrochloride
  • HY-W879007
    ICG-azide

    		Fluorescent Dye Others
    ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
    ICG-azide
  • HY-160893
    PSMA-Val-Cit-PAB-Azide

    		Drug-Linker Conjugates for ADC PSMA Cancer
    PSMA-Val-Cit-PAB-Azide is a drug-linker conjugate for ADC. PSMA-Val-Cit-PAB-Azide contains the cleavable ADCs linker (Val-Cit-PAB) and a novel small-molecule PSMA-targeted conjugate. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups .
    PSMA-Val-Cit-PAB-Azide
  • HY-155639
    Tyramide alkyne
    1 Publications Verification

    		 Others Others
    Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction. Tyramide alkyne can be used for ascorbate peroxidase 2 (APEX2) labeling .
    Tyramide alkyne
  • HY-130109
    N3-PEG4-C2-NHS ester

    		ADC Linker Cancer
    N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    N3-PEG4-C2-NHS ester
  • HY-159708
    Ionizable lipid Az1

    		Liposome Others
    Ionizable lipid Az1is an ionizable lipid which can react with a variety of terminal alkynes under the CuAAC standard condition .
    Ionizable lipid Az1
  • HY-W051612
    DL-Propargylglycine hydrochloride

    		Amino Acid Derivatives Others
    DL-Propargylglycine hydrochloride is a Glycine (HY-Y0966) derivative. DL-Propargylglycine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    DL-Propargylglycine hydrochloride
  • HY-D2230
    Cy3.5 alkyne

    		Fluorescent Dye Others
    Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .
    Cy3.5 alkyne
  • HY-106203B
    (R)-Crinecerfont

    (R)-SSR-125543

    		 CFTR Metabolic Disease
    (R)-Crinecerfont is the R-enantiomer of Crinecerfont (HY-106203). Crinecerfont (SSR-125543) is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research. Crinecerfont is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    (R)-Crinecerfont
  • HY-157510
    Thalidomide-O-C3-azide

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide-O-C3-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C3-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C3-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
    Thalidomide-O-C3-azide
  • HY-157511
    Thalidomide-O-C5-azide

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide-O-C5-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C5-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C5-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
    Thalidomide-O-C5-azide
  • HY-157515
    Thalidomide 4'-ether-PEG2-azide

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide 4'-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4'-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4'-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
    Thalidomide 4'-ether-PEG2-azide
  • HY-B0110
    Gestodene

    SHB 331; WL 70

    		 Progesterone Receptor Endocrinology
    Gestodene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Gestodene
  • HY-B1012
    Quinestrol

    W-3566

    		 Estrogen Receptor/ERR Endocrinology Cancer
    Quinestrol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Quinestrol
  • HY-B1089
    Ethynodiol diacetate

    Ethynodiol acetate

    		 Progesterone Receptor Endocrinology
    Ethynodiol diacetate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ethynodiol diacetate
  • HY-13967
    AMG 837

    		Free Fatty Acid Receptor Metabolic Disease
    AMG 837 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    AMG 837
  • HY-13967A
    AMG 837 sodium salt

    		Free Fatty Acid Receptor Metabolic Disease
    AMG 837 (sodium salt) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    AMG 837 sodium salt
  • HY-G0018
    Norgestimate metabolite Norelgestromin

    17-Deacetyl norgestimate; 17-Deacylnorgestimate

    		 Drug Metabolite Others
    Norgestimate metabolite Norelgestromin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate metabolite Norelgestromin
  • HY-W615104
    BTTP

    		Others Others
    BTTP is a tris(triazolylmethyl)amine-based ligand. BTTP can accelerate the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), the prototypical reaction in click chemistry .
    BTTP
  • HY-D1320
    Cyanine5 azide chloride

    		Fluorescent Dye Others
    Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Cyanine5 azide chloride
  • HY-13971
    GPR40 Activator 1

    		Free Fatty Acid Receptor Metabolic Disease
    GPR40 Activator 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    GPR40 Activator 1
  • HY-W007319
    Phenylpropiolic acid

    		Endogenous Metabolite Metabolic Disease
    Phenylpropiolic acid is an endogenous metabolite. Phenylpropiolic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Phenylpropiolic acid
  • HY-50713
    Calcium-Sensing Receptor Antagonists I

    		CaSR Others
    Calcium-Sensing Receptor Antagonists I is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Calcium-Sensing Receptor Antagonists I
  • HY-N11835
    Asparenyldiol

    Asparenydiol

    		 Others Others
    Asparenyldiol (Asparenydiol) is a antioxidant agent . Asparenyldiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Asparenyldiol
  • HY-101658
    Pargolol hydrochloride

    Ko 1400 hydrochloride

    		 Adrenergic Receptor Neurological Disease Endocrinology
    Pargolol hydrochloride is a β adrenergic receptor antagonist. Pargolol hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Pargolol hydrochloride
  • HY-139672
    BRD5018

    		Parasite Infection
    BRD5018 is an antimalarial agent. BRD5018 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    BRD5018
  • HY-W440998
    DSPE-alkyne

    		Liposome Others
    DSPE-alkyne is a phospholipid . DSPE-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    DSPE-alkyne
  • HY-124031
    Lobetyolinin

    		Others Cardiovascular Disease
    Lobetyolinin shows anti-arrhythmic activity . Lobetyolinin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Lobetyolinin
  • HY-U00055
    Temiverine hydrochloride

    		mAChR Neurological Disease
    Temiverine hydrochloride is a synthesized agent that is expected to have anticholinergic action. Temiverine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Temiverine hydrochloride
  • HY-B1710
    Norethindrone acetate

    19-Norethindrone acetate

    		 Progesterone Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Norethindrone acetate is a female hormone used for the research of endometriosis . Norethindrone acetate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norethindrone acetate
  • HY-107362
    CH7057288

    		Trk Receptor Cancer
    CH7057288 is a potent and selective TRK inhibitor. CH7057288 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CH7057288
  • HY-N3114
    Panaxydiol

    		Histamine Receptor Inflammation/Immunology
    Panaxydiol exhibits histamine-release inhibition activity . Panaxydiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Panaxydiol
  • HY-D1321
    Cy 5 amine hydrochloride

    Cyanine5 amine hydrochloride

    		 Fluorescent Dye Others
    Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) .
    Cy 5 amine hydrochloride
  • HY-147420
    Xelaglifam

    IDG-16177

    		 Free Fatty Acid Receptor Metabolic Disease
    Xelaglifam is a potent GPR40 agonist. Antihyperglycaemic activity . Xelaglifam is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Xelaglifam
  • HY-148793
    Resencatinib

    		c-Met/HGFR Cancer
    Resencatinib is a potent tyrosine kinase inhibitor with antineoplastic activity . Resencatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Resencatinib
  • HY-132050
    Azido-PEG4-propargyl

    		PROTAC Linkers Cancer
    Azido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Azido-PEG4-propargyl
  • HY-138391
    Azido-PEG8-propargyl

    		PROTAC Linkers Cancer
    Azido-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Azido-PEG8-propargyl
  • HY-138739
    Azido-PEG10-propargyl

    		PROTAC Linkers Cancer
    Azido-PEG10-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Azido-PEG10-propargyl
  • HY-138741
    Azido-PEG12-propargyl

    		PROTAC Linkers Cancer
    Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG12-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Azido-PEG12-propargyl
  • HY-151823
    8-Azido-octanoyl-OSu

    		ADC Linker Others
    8-Azido-octanoyl-OSu is a click chemistry reagent containing an azide group. Used as a building block to introduce 8-azidooctanoic acid (CAS 217180-76-2) fragment. This fragment is used for further modifications using Click-chemistry (CuAAC), as a protected aminogroup or is used in physico-chemical investigations . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    8-Azido-octanoyl-OSu
  • HY-N7622
    Acetylatractylodinol

    Tractylodinol acetate

    		 Others Others
    Acetylatractylodinol, isolated from Atractylodes lancea, possesses antioxidant activity . Acetylatractylodinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Acetylatractylodinol
  • HY-135636
    Ponatinib Acid

    		Fluorescent Dye Others
    Ponatinib Acid, an analogue of Ponatinib, is usually used as a labeled chemical or fluorescent probe. Ponatinib Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ponatinib Acid
  • HY-105102
    Netivudine

    882C87

    		 Nucleoside Antimetabolite/Analog HSV Infection
    Netivudine is a nucleoside analogue with potent anti-varicella zoster virus activity. Netivudine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Netivudine
  • HY-W004784
    3-Butynoic acid

    		Endogenous Metabolite Others
    3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase . 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    3-Butynoic acid
  • HY-12008
    Erlotinib Hydrochloride
    Maximum Cited Publications
    88 Publications Verification

    CP-358774 hydrochloride; NSC 718781 hydrochloride; OSI-774 hydrochloride

    		 EGFR Autophagy Cancer
    Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib Hydrochloride
  • HY-15458
    SAR131675
    5+ Cited Publications

    		 VEGFR Cancer
    SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    SAR131675
  • HY-12008A
    Erlotinib mesylate

    CP-358774 mesylate; NSC 718781 mesylate; OSI-774 mesylate

    		 EGFR Autophagy Cancer
    Erlotinib mesylate (CP-358774 mesylate) inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib mesylate
  • HY-102033
    Oxamflatin

    Metacept-3

    		 HDAC Cancer
    Oxamflatin (Metacept-3) is a potent HDAC inhibitor with an IC50 of 15.7 nM. Oxamflatin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Oxamflatin
  • HY-147621
    FGFR-IN-6

    		FGFR Cancer
    FGFR-IN-6 (Compound 5) is a FGFR inhibitor . FGFR-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    FGFR-IN-6
  • HY-W040124
    DL-Propargylglycine

    		Amino Acid Derivatives Others
    DL-Propargylglycine is a Glycine (HY-Y0966) derivative . DL-Propargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    DL-Propargylglycine

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