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Results for "

Src homology phosphatase 2

" in MedChemExpress (MCE) Product Catalog:

646

Inhibitors & Agonists

2

Screening Libraries

15

Fluorescent Dye

23

Biochemical Assay Reagents

62

Peptides

4

MCE Kits

97

Natural
Products

120

Recombinant Proteins

19

Isotope-Labeled Compounds

52

Antibodies

4

Click Chemistry

7

Oligonucleotides

Cat. No. Product Name Target Research Area
  • HY-P3744
    pp60v-src Autophosphorylation site

    		Peptides Others
    pp60v-src Autophosphorylation site is a synthetic peptide. pp60v-src Autophosphorylation site can be used for various biochemical studies .
  • HY-P1199
    pp60 c-src (521-533) (phosphorylated)

    		Peptides Others
    pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527 .
  • HY-P2513
    Src Optimal Peptide Substrate

    		Peptides Others
    Src Optimal Peptide Substrate is a highly specific Src substrate. Src Optimal Peptide Substrate can used to measure the Src activity .
  • HY-P0200
    RR-SRC

    		Src Inflammation/Immunology
    RR-SRC is a substrate for src-tyrosine-specific protein kinase .
  • HY-P5464
    SRC-1 NR box peptide

    		Peptides Others
    SRC-1 NR box peptide is a biological active peptide. (This peptide is a 14-amino acid fragment from the steroid receptor cofactor SRC-1 NR II.)
  • HY-P5458
    SRC-1 (686-700)

    		Mineralocorticoid Receptor Others
    SRC-1 (686-700) is a biological active peptide. (This peptide is amino acids 686 to 700 fragment containing the second LXXLL motif, derived from NR box II of steroid receptor coactivator (SRC1). Coactivator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription.)
  • HY-P3743
    p60c-src Substrate

    		Src Peptides Others
    p60c-src Substrate is an efficient and specific substrate for p60c-src protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides [2].
  • HY-P3773
    p60c-src substrate II

    		Src Cancer
    p60c-src substrate II is an efficient pentapeptide substrate for the tyrosine kinase pp60c-src .
  • HY-P2372
    P60v-src(137-157)

    		Peptides Others
    P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60 v-src (IC50: 7.5 μM) [2].
  • HY-P3771
    p60c-src substrate II, phosphorylated

    		Src Others
    p60c-src substrate II, phosphorylated is a pentapeptide. p60c-src substrate II, phosphorylated is a p60c-src substrate II phosphorylated polypeptide. Protein phosphorylation is an important post-translationmodification of protein that is indispensible in biological regulations .
  • HY-P3279
    EPQpYEEIPIYL
    1 Publications Verification

    		 Src Cancer
    EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains [2].
  • HY-P2548
    pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

    		EGFR Others
    pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification .
  • HY-P3633
    Locustatachykinin II

    Lom-TK II

    		 Peptides Neurological Disease
    Locustatachykinin II (Lom-TK II) is an insect neuropeptide with homology to peptides of the vertebrate tachykinin family. Locustatachykinin II can be used for the research of insect endocrine .
  • HY-P2040
    Nodularin

    		Phosphatase Cancer
    Nodularin is a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor .
  • HY-P5363
    PAP 248–286

    Prostatic Acid phosphatase(248-286)

    		 HIV Others
    PAP 248–286 is a biological active peptide. (Prostatic Acid Phosphatase (248-286), PAP (248-286) peptide is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells.)
  • HY-P5996
    MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2

    		Fluorescent Dye Others
    MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2 is a protein tyrosine phosphatase fluorogenic substrate that can be detected at 393 nm (with excitation at 325 nm) .
  • HY-W141781
    Cysteamine S-phosphate sodium

    Cystaphos sodium

    		 Phosphatase Metabolic Disease
    Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant [2].
  • HY-P0320A
    EGF Receptor Substrate 2 (Phospho-Tyr5) (TFA)

    		Phosphatase Biochemical Assay Reagents Others
    EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .
  • HY-P0320B
    EGF Receptor Substrate 2 (Phospho-Tyr5) (acetate)

    		Phosphatase Biochemical Assay Reagents Others
    EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .
  • HY-P1247
    Calcineurin autoinhibitory peptide

    		Phosphatase Neurological Disease
    Calcineurin autoinhibitory peptide is a selective inhibitor of Ca 2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. Calcineurin autoinhibitory peptide could protect neurons from excitatory neuronal death [2].
  • HY-P1247A
    Calcineurin autoinhibitory peptide TFA

    		Phosphatase Neurological Disease
    Calcineurin autoinhibitory peptide TFA is a selective inhibitor of Ca 2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. Calcineurin autoinhibitory peptide TFA could protect neurons from excitatory neuronal death [2].
  • HY-P10527
    CSK substrate

    		Src Others
    CSK substrate is a specific substrate for C-terminal Src kinase (CSK), which binds CSK and downregulates the Src family members. CSK substrate preferentially phosphorylates certain amino acid residues that are distinct from the conserved Src C-terminal sequence .
  • HY-W007599
    (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid

    		Peptides Cancer
    (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer, as a nonviral gene vectors, realizes the method in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid also involves in the synthesis of an organic substance that increases the luminescence intensity of alkaline phosphatase substrates [2].
  • HY-P1183
    Locustatachykinin I

    		Peptides Neurological Disease Endocrinology
    Locustatachykinin I is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I is also a substrate for a deamidase [2].
  • HY-P0139
    Gap 27
    5 Publications Verification

    		 Gap Junction Protein Cardiovascular Disease
    Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment [2].
  • HY-P1183A
    Locustatachykinin I TFA

    		Peptides Neurological Disease Endocrinology
    Locustatachykinin I TFA is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I TFA exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I TFA is also a substrate for a deamidase [2].
  • HY-P2547
    Tyrosine Kinase Peptide 1

    		Src Others
    Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay .
  • HY-P2413
    Ac-PPPHPHARIK-NH2

    		Peptides Others
    Ac-PPPHPHARIK-NH2 (compound S1) is a compound that inhibits the interaction between androgen receptor and Src. It can inhibit the binding of androgen or estrogen-induced receptor and Src in cancer cells, as well as the activation of related signaling pathways, and can also inhibit cell cycle progression and tumor growth.
  • HY-P5447
    RRLIEDAEpYAARG

    		Phosphatase Others
    RRLIEDAEpYAARG is a biological active peptide. (Phosphatase substrate.)
  • HY-P1984
    Alphostatin

    		Phosphatase Others
    Alphostatin is a bovine liver alkaline phosphatase inhibitor .
  • HY-P3284
    Mastoparan M tetraacetate

    		Peptides Cancer
    Mastoparan M tetraacetate is a tetrapeptide amide isolated from the Chinese giant hornet (Vespa mandarinia). The amino acid sequence of Mastoparan M tetraacetate shares some structural homology with Mastoparan X, a wasp venom isolated from the Chinese giant hornet as well .
  • HY-P10697
    VH4127

    		LDLR Metabolic Disease
    VH4127 is a cyclic peptide targeting the low density lipoprotein receptor (LDLR) with a KD of 18 nM for hLDLR. VH4127, bearing non-natural amino acid residues, specifically binds to rodent and human epidermal growth factor (EGF) homology domain of LDLR [2].
  • HY-P10372
    pFYN peptide

    		Src Cancer
    pFYN peptide is a biotin-labled phosphorylated peptide substrate derived from FYN (a Src family kinase) .
  • HY-P5559
    ND1-YL2

    		PROTACs Cancer
    ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research .
  • HY-P5441A
    KRpTIRR acetate

    		Phosphatase Others
    KRpTIRR acetate is a phosphothreonine-containing peptide that serves as a substrate for phosphatases .
  • HY-P5441
    KRpTIRR

    		Phosphatase Others
    KRpTIRR is a phosphothreonine-containing peptide and can serve as a substrate for phosphatases .
  • HY-P1816
    Fibronectin CS1 Peptide

    		Integrin Cancer
    The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models .
  • HY-P6028
    GSNKSKPK-NH2

    		Peptides Others
    GSNKSKPK-NH2 is a model peptide based on a c-Src N-terminal peptide that can be used as NMT substrate .
  • HY-P6028A
    GSNKSKPK-NH2 TFA

    		Peptides Others
    GSNKSKPK-NH2 TFA is a model peptide based on a c-Src N-terminal peptide that can be used as NMT substrate .
  • HY-P5489
    IGRP(206-214)

    		Phosphatase Others
    IGRP(206-214) is a biological active peptide. (This peptide corresponds to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). This peptide is T cells specific for proinsulin and IGRP induces diabetes in non-obese diabetic (NOD) mice.)
  • HY-P10665
    pYEEI

    		Src Cancer
    pYEEI is a phosphotyrosine-containing tetrapeptide binds to Src SH2 domain with the Kd of 100 nM and with the IC50 of 6.5 μM. pYEEI plays an important role in cancer research .
  • HY-P1200
    Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

    		Src Cancer
    Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions .
  • HY-P3463
    Beinaglutide

    GLP-1 (human)

    		 GCGR Metabolic Disease Inflammation/Immunology
    Beinaglutide is a human GLP-1 polypeptide that shares almost 100% homology with human GLP-1 (7–36). Beinaglutide displays does-dependent effects in glycemic control, inhibiting food intake and gastric empty and promoting weight loss. Beinaglutide has the potential for the research of overweight/obesity and nonalcoholic steatohepatitis (NASH) [2].
  • HY-P1200A
    Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA

    		Src Cancer
    Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions .
  • HY-P10544
    Humanized anti-tac (HAT) binding peptide

    		Interleukin Related Others
    Humanized anti-tac (HAT) binding peptide is a peptide that can specifically bind to the Fc region of HAT. HAT is a humanized monoclonal antibody against the low affinity p55 subunit of the interleukin IL-2 receptor. Humanized anti-tac (HAT) binding peptide can be used to develop affinity chromatography media to purify specific monoclonal antibodies .
  • HY-P10671
    WVSAV

    		Phosphatase Others
    WVSAV is a ligand of the PDZ2 domain (Tyrosine Phosphatase) with a Kd value of 111 μM. WVSAV can be used for binding studies in the field of protein-ligand interactions .
  • HY-P1784
    Secretin, canine

    		Secretin Receptor Endocrinology
    Secretin, canine is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Secretin, canine can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway .
  • HY-P3677
    Neuropeptide Y (2-36) (porcine)

    		Neuropeptide Y Receptor Neurological Disease
    Neuropeptide Y (2-36) (porcine) is a porcine-derived neuropeptide with 97.14% homology to rat/human origin. Neuropeptide Y (2-36) (porcine) is also a rat neuropeptide receptor agonist, with EC50 values of 1.2, 1.6 and 3.4 nM for receptor of Y5, Y2 and Y1 respectively. Neuropeptide Y (2-36) (porcine) can be used in studies related to obesity and eating disorders .
  • HY-P4835
    pTH (2-34) (human)

    		Phosphatase Others
    pTH (2-34) (human) (80 μg/kg) slightly increases serum osteocalcin levels and alkaline phosphatase activity of bone extract (markers of bone formation) in mice. pTH (2-34) is not as effective as pTH (1-34) .
  • HY-P0320
    EGF Receptor Substrate 2 (Phospho-Tyr5)

    		Phosphatase Others
    EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

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